JP7109784B2 - 遺伝子編集のための進化したＣａｓ９蛋白質 - Google Patents

遺伝子編集のための進化したＣａｓ９蛋白質 Download PDF

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JP7109784B2
JP7109784B2 JP2018521045A JP2018521045A JP7109784B2 JP 7109784 B2 JP7109784 B2 JP 7109784B2 JP 2018521045 A JP2018521045 A JP 2018521045A JP 2018521045 A JP2018521045 A JP 2018521045A JP 7109784 B2 JP7109784 B2 JP 7109784B2
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cas9
amino acid
seq
protein
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JP2018537963A5 (enExample
JP2018537963A (ja
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リウ，デイビッド，アール．
フー，ジョニー，ハオ
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Harvard University
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JP2018521045A 2015-10-23 2016-10-22 遺伝子編集のための進化したＣａｓ９蛋白質 Active JP7109784B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2022058736A JP7525174B2 (ja) 2015-10-23 2022-03-31 遺伝子編集のための進化したＣａｓ９蛋白質
JP2024058782A JP2024125281A (ja) 2015-10-23 2024-04-01 遺伝子編集のための進化したＣａｓ９蛋白質
JP2026052200A JP2026116287A (ja) 2015-10-23 2026-03-26 遺伝子編集のための進化したＣａｓ９蛋白質

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US201562245828P 2015-10-23 2015-10-23
US62/245,828 2015-10-23
US201662279346P 2016-01-15 2016-01-15
US62/279,346 2016-01-15
US201662311763P 2016-03-22 2016-03-22
US62/311,763 2016-03-22
US201662322178P 2016-04-13 2016-04-13
US62/322,178 2016-04-13
US201662357352P 2016-06-30 2016-06-30
US201662357332P 2016-06-30 2016-06-30
US62/357,352 2016-06-30
US62/357,332 2016-06-30
US201662370700P 2016-08-03 2016-08-03
US62/370,700 2016-08-03
US201662398490P 2016-09-22 2016-09-22
US62/398,490 2016-09-22
US201662408686P 2016-10-14 2016-10-14
US62/408,686 2016-10-14
PCT/US2016/058345 WO2017070633A2 (en) 2015-10-23 2016-10-22 Evolved cas9 proteins for gene editing

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JP2018537963A JP2018537963A (ja) 2018-12-27
JP2018537963A5 JP2018537963A5 (enExample) 2020-02-27
JP7109784B2 true JP7109784B2 (ja) 2022-08-01

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JP2018521045A Active JP7109784B2 (ja) 2015-10-23 2016-10-22 遺伝子編集のための進化したＣａｓ９蛋白質
JP2018521096A Active JP7067793B2 (ja) 2015-10-23 2016-10-22 核酸塩基編集因子およびその使用
JP2022000227A Active JP7531923B2 (ja) 2015-10-23 2022-01-04 核酸塩基編集因子およびその使用
JP2022058736A Active JP7525174B2 (ja) 2015-10-23 2022-03-31 遺伝子編集のための進化したＣａｓ９蛋白質
JP2024058782A Pending JP2024125281A (ja) 2015-10-23 2024-04-01 遺伝子編集のための進化したＣａｓ９蛋白質
JP2024118365A Pending JP2024164012A (ja) 2015-10-23 2024-07-24 核酸塩基編集因子およびその使用
JP2026052200A Pending JP2026116287A (ja) 2015-10-23 2026-03-26 遺伝子編集のための進化したＣａｓ９蛋白質

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JP2018521096A Active JP7067793B2 (ja) 2015-10-23 2016-10-22 核酸塩基編集因子およびその使用
JP2022000227A Active JP7531923B2 (ja) 2015-10-23 2022-01-04 核酸塩基編集因子およびその使用
JP2022058736A Active JP7525174B2 (ja) 2015-10-23 2022-03-31 遺伝子編集のための進化したＣａｓ９蛋白質
JP2024058782A Pending JP2024125281A (ja) 2015-10-23 2024-04-01 遺伝子編集のための進化したＣａｓ９蛋白質
JP2024118365A Pending JP2024164012A (ja) 2015-10-23 2024-07-24 核酸塩基編集因子およびその使用
JP2026052200A Pending JP2026116287A (ja) 2015-10-23 2026-03-26 遺伝子編集のための進化したＣａｓ９蛋白質

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US (6) US12043852B2 (enExample)
EP (4) EP3365357B1 (enExample)
JP (7) JP7109784B2 (enExample)
KR (1) KR20180069898A (enExample)
CN (2) CN108513575A (enExample)
AU (3) AU2016342380B2 (enExample)
CA (1) CA3002827A1 (enExample)
IL (4) IL310721B2 (enExample)
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Cited By (1)

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JP2022124487A (ja) * 2015-10-23 2022-08-25 プレジデント アンド フェローズ オブ ハーバード カレッジ 遺伝子編集のための進化したＣａｓ９蛋白質

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US9163284B2 (en) 2013-08-09 2015-10-20 President And Fellows Of Harvard College Methods for identifying a target site of a Cas9 nuclease
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