US6399296B1
(en)
*
|
1994-07-20 |
2002-06-04 |
The General Hospital Corporation |
Interaction trap systems for detecting protein interactions
|
US5731168A
(en)
*
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
US6066617A
(en)
*
|
1996-04-03 |
2000-05-23 |
Human Genome Sciences, Inc. |
Human cystatin F
|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
IL127892A0
(en)
*
|
1996-07-12 |
1999-10-28 |
Genentech Inc |
Gamma-heregulin
|
EP0938556B1
(en)
|
1996-07-12 |
2005-03-09 |
Genentech, Inc. |
Gamma-heregulin
|
IL130061A
(en)
|
1996-11-27 |
2001-09-13 |
Genentech Inc |
Affinity purification of polypeptide on protein a matrix
|
US20040038894A1
(en)
*
|
1996-12-31 |
2004-02-26 |
Institut National De La Sante Et De La Recherche Medicale (I.N.S.E.R.M.) |
Compounds for modulating cell negative regulations and biological applications thereof
|
US6045774A
(en)
*
|
1997-01-10 |
2000-04-04 |
Epicyte Pharmaceutical Inc. |
J chain polypeptide targeting molecule linked to an imaging agent
|
KR100856995B1
(ko)
|
1997-04-07 |
2008-09-04 |
제넨테크, 인크. |
인간화 항체 및 인간화 항체의 제조 방법
|
DE122007000021I1
(de)
|
1997-04-07 |
2007-05-24 |
Genentech Inc |
Anti-vefg Antibodies
|
US7951917B1
(en)
|
1997-05-02 |
2011-05-31 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
US20030207346A1
(en)
*
|
1997-05-02 |
2003-11-06 |
William R. Arathoon |
Method for making multispecific antibodies having heteromultimeric and common components
|
US20020062010A1
(en)
*
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
EP0979281B1
(en)
*
|
1997-05-02 |
2005-07-20 |
Genentech, Inc. |
A method for making multispecific antibodies having heteromultimeric and common components
|
JP2001510483A
(ja)
|
1997-06-13 |
2001-07-31 |
ジェネンテク,インコーポレイテッド |
タンパク質の回収
|
DE69714035T2
(de)
|
1997-08-14 |
2003-03-06 |
Sulzer Innotec Ag, Winterthur |
Zusammensetzung und Vorrichtung zur Reparatur von Knorpelgewebe in vivo bestehend aus Nanokapseln mit osteoinduktiven und/oder chondroinduktiven Faktoren
|
US8088386B2
(en)
|
1998-03-20 |
2012-01-03 |
Genentech, Inc. |
Treatment of complement-associated disorders
|
ATE293994T1
(de)
*
|
1997-12-01 |
2005-05-15 |
Fang Fang |
Multivalente rekombinante antikörper zur behandlung von hrv infektionen
|
US6451977B1
(en)
*
|
1998-02-26 |
2002-09-17 |
Genentech, Inc. |
Fused polypeptides
|
EP1941905A1
(en)
|
1998-03-27 |
2008-07-09 |
Genentech, Inc. |
APO-2 Ligand-anti-her-2 antibody synergism
|
US6194551B1
(en)
*
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
US6528624B1
(en)
*
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
NZ508878A
(en)
|
1998-05-15 |
2003-08-29 |
Genentech Inc |
IL-17B and IL-17Cactive variants of IL-17 which stimulates epithelial, endothelial and fibroblastic cells
|
EP3112468A1
(en)
|
1998-05-15 |
2017-01-04 |
Genentech, Inc. |
Il-17 homologous polypeptides and therapeutic uses thereof
|
EP1865061A3
(en)
|
1998-05-15 |
2007-12-19 |
Genentech, Inc. |
IL-17 homologous polypeptides and therapeutic uses thereof
|
JP2002517223A
(ja)
|
1998-06-12 |
2002-06-18 |
ジェネンテック・インコーポレーテッド |
モノクローナル抗体、交叉反応性抗体およびそれを生成する方法
|
US20020172678A1
(en)
|
2000-06-23 |
2002-11-21 |
Napoleone Ferrara |
EG-VEGF nucleic acids and polypeptides and methods of use
|
WO2000029431A1
(en)
*
|
1998-11-17 |
2000-05-25 |
Tanox, Inc. |
Bispecific molecules cross-linking itim and itam for therapy
|
EP1950300A3
(en)
|
1998-11-18 |
2011-03-23 |
Genentech, Inc. |
Antibody variants with higher binding affinity compared to parent antibodies
|
US20030035798A1
(en)
*
|
2000-08-16 |
2003-02-20 |
Fang Fang |
Humanized antibodies
|
EP1484338B1
(en)
|
1998-12-22 |
2007-02-07 |
Genentech, Inc. |
Methods and compositions for inhibiting neoplastic cell growth
|
US7833529B1
(en)
|
1999-01-07 |
2010-11-16 |
Zymogenetics, Inc. |
Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor
|
US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
PL209786B1
(pl)
*
|
1999-01-15 |
2011-10-31 |
Genentech Inc |
Przeciwciało zawierające wariant regionu Fc ludzkiej IgG1, przeciwciało wiążące czynnik wzrostu śródbłonka naczyń oraz immunoadhezyna
|
US6737056B1
(en)
*
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
WO2000064327A2
(en)
*
|
1999-04-26 |
2000-11-02 |
Duke University |
Inhibition of complement action
|
EP1953173B1
(en)
|
1999-06-15 |
2009-11-18 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids endoding the same
|
WO2001000244A2
(en)
|
1999-06-25 |
2001-01-04 |
Genentech, Inc. |
METHODS OF TREATMENT USING ANTI-ErbB ANTIBODY-MAYTANSINOID CONJUGATES
|
DE10084743T1
(de)
|
1999-06-25 |
2002-08-14 |
Genentech Inc |
Humanisierte Anti-ErbB2-Antikörper und Behandlung mit Anti-ErbB2-Antikörpern
|
SK782002A3
(en)
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
GB9919597D0
(en)
*
|
1999-08-18 |
1999-10-20 |
Oxford Glycosciences Uk Ltd |
Methods and compositions for diagnosis of hepatoma
|
TR200200472T2
(tr)
|
1999-08-27 |
2002-06-21 |
Genentech, Inc. |
Anti-Erb B2 antikorları ile tedavi için dozajlar
|
EP1686134A3
(en)
|
1999-12-01 |
2006-08-09 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
EP1897945B1
(en)
|
1999-12-23 |
2012-01-18 |
Genentech, Inc. |
IL-17 homologous polypeptides and therapeutic uses thereof
|
ATE424457T1
(de)
|
2000-01-13 |
2009-03-15 |
Genentech Inc |
Menschliche stra6 polypeptide
|
KR20020073181A
(ko)
|
2000-01-25 |
2002-09-19 |
제넨테크, 인크. |
Liv-1 관련 단백질, 이를 코딩하는 폴리뉴클레오티드및 암의 치료를 위한 그의 용도
|
US6740520B2
(en)
|
2000-03-21 |
2004-05-25 |
Genentech, Inc. |
Cytokine receptor and nucleic acids encoding the same
|
KR20020093029A
(ko)
|
2000-04-11 |
2002-12-12 |
제넨테크, 인크. |
다가 항체 및 그의 용도
|
US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
US6696620B2
(en)
|
2000-05-02 |
2004-02-24 |
Epicyte Pharmaceutical, Inc. |
Immunoglobulin binding protein arrays in eukaryotic cells
|
EP1299128A2
(en)
|
2000-06-20 |
2003-04-09 |
Idec Pharmaceuticals Corporation |
Cold anti-cd20 antibody/radiolabeled anti-cd22 antibody combination
|
ATE415978T1
(de)
|
2000-07-27 |
2008-12-15 |
Genentech Inc |
Sequentielle verabreichung von cpt-11 und apo-2l polypeptid
|
US6984522B2
(en)
|
2000-08-03 |
2006-01-10 |
Regents Of The University Of Michigan |
Isolation and use of solid tumor stem cells
|
UA81743C2
(uk)
|
2000-08-07 |
2008-02-11 |
Центокор, Инк. |
МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
|
US6902734B2
(en)
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
US7288390B2
(en)
|
2000-08-07 |
2007-10-30 |
Centocor, Inc. |
Anti-dual integrin antibodies, compositions, methods and uses
|
ATE412009T1
(de)
|
2000-08-24 |
2008-11-15 |
Genentech Inc |
Methode zur inhibierung von il-22 induziertem pap1
|
EP1944317A3
(en)
|
2000-09-01 |
2008-09-17 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
CA2420475A1
(en)
|
2000-09-26 |
2002-04-04 |
Genentech, Inc. |
Ige receptor antagonists
|
US8153121B2
(en)
|
2000-10-06 |
2012-04-10 |
Los Angeles Biomedical Research Institute at Harbor—UCLA Medical Center |
Diagnosis and therapy of antibody-mediated inflammatory autoimmune disorders
|
US8178304B2
(en)
*
|
2000-10-06 |
2012-05-15 |
Smith Terry J |
Diagnostic methods relating to Graves' disease and other autoimmune disorders
|
SI1324776T2
(en)
|
2000-10-12 |
2018-06-29 |
Genentech, Inc. |
Concentrated protein formulations with reduced viscosity
|
US7408041B2
(en)
|
2000-12-08 |
2008-08-05 |
Alexion Pharmaceuticals, Inc. |
Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
|
EP1341902A2
(en)
|
2000-12-08 |
2003-09-10 |
Alexion Pharmaceuticals, Inc. |
Chronic lymphocytic leukemia cell line and its use for producing an antibody
|
US9249229B2
(en)
|
2000-12-08 |
2016-02-02 |
Alexion Pharmaceuticals, Inc. |
Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
|
US20060057651A1
(en)
|
2000-12-08 |
2006-03-16 |
Bowdish Katherine S |
Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
|
US6492327B2
(en)
*
|
2000-12-19 |
2002-12-10 |
Sulzer Biologics Inc. |
Isolation of purified TGF- β1 and TGF -β2 from bone tissue
|
US20020159996A1
(en)
|
2001-01-31 |
2002-10-31 |
Kandasamy Hariharan |
Use of CD23 antagonists for the treatment of neoplastic disorders
|
EP2301971A1
(en)
|
2001-02-20 |
2011-03-30 |
ZymoGenetics, L.L.C. |
Antibodies that bind both BCMA and TACI
|
US20020155109A1
(en)
*
|
2001-04-20 |
2002-10-24 |
Lynch David H. |
Bispecific antibodies that bind TRAIL-R1 and TRAIL-R2
|
KR101021124B1
(ko)
|
2001-05-24 |
2011-03-14 |
지모제넥틱스, 인코포레이티드 |
Taci-면역글로불린 융합 단백질
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
CA2633413C
(en)
|
2001-06-20 |
2012-08-21 |
Genentech, Inc. |
Antibodies against tumor-associated antigenic target (tat) polypeptides
|
AR034749A1
(es)
*
|
2001-07-09 |
2004-03-17 |
Schering Ag |
Formulaciones de interferon beta humano
|
JP2005522192A
(ja)
|
2001-07-19 |
2005-07-28 |
パーラン セラピューティクス, インコーポレイテッド |
マルチマータンパク質およびマルチマータンパク質を作製および使用する方法
|
US6833441B2
(en)
|
2001-08-01 |
2004-12-21 |
Abmaxis, Inc. |
Compositions and methods for generating chimeric heteromultimers
|
US20040235068A1
(en)
*
|
2001-09-05 |
2004-11-25 |
Levinson Arthur D. |
Methods for the identification of polypeptide antigens associated with disorders involving aberrant cell proliferation and compositions useful for the treatment of such disorders
|
ATE516042T1
(de)
|
2001-09-18 |
2011-07-15 |
Genentech Inc |
Zusammensetzungen und verfahren zur behandlung und diagnose von tumoren
|
US7981863B2
(en)
|
2001-09-19 |
2011-07-19 |
Neuronova Ab |
Treatment of Parkinson's disease with PDGF
|
WO2003029436A2
(en)
|
2001-10-04 |
2003-04-10 |
Immunex Corporation |
Ul16 binding protein 4
|
US7122351B2
(en)
*
|
2001-10-19 |
2006-10-17 |
Zymogenetics, Inc. |
Dimerized PDGF-D and materials and methods for producing it
|
MXPA04003798A
(es)
*
|
2001-10-25 |
2004-07-30 |
Genentech Inc |
Composiciones de glicoproteina.
|
US7175983B2
(en)
*
|
2001-11-02 |
2007-02-13 |
Abmaxis, Inc. |
Adapter-directed display systems
|
ES2624547T3
(es)
|
2001-11-14 |
2017-07-14 |
Janssen Biotech, Inc. |
Anticuerpos anti il 6, composiciones, métodos y usos
|
US20050171339A1
(en)
|
2001-12-28 |
2005-08-04 |
Izumi Sugo |
Method of stabilizing protein
|
EP2067472A1
(en)
|
2002-01-02 |
2009-06-10 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
WO2003066662A2
(en)
|
2002-02-05 |
2003-08-14 |
Genentech, Inc. |
Protein purification
|
EP2388265A1
(en)
|
2002-02-22 |
2011-11-23 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
US8188231B2
(en)
|
2002-09-27 |
2012-05-29 |
Xencor, Inc. |
Optimized FC variants
|
US20080260731A1
(en)
*
|
2002-03-01 |
2008-10-23 |
Bernett Matthew J |
Optimized antibodies that target cd19
|
US20080254027A1
(en)
*
|
2002-03-01 |
2008-10-16 |
Bernett Matthew J |
Optimized CD5 antibodies and methods of using the same
|
US7317091B2
(en)
*
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
US20040132101A1
(en)
*
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
US20070148171A1
(en)
*
|
2002-09-27 |
2007-06-28 |
Xencor, Inc. |
Optimized anti-CD30 antibodies
|
US7662925B2
(en)
*
|
2002-03-01 |
2010-02-16 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
SI2289942T1
(sl)
|
2002-04-10 |
2013-11-29 |
Genentech, Inc. |
Variante protitelesa proti HER2
|
AU2003230874A1
(en)
|
2002-04-16 |
2003-11-03 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
US7622562B2
(en)
|
2002-06-26 |
2009-11-24 |
Zimmer Orthobiologics, Inc. |
Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
|
AU2003247806B2
(en)
|
2002-07-08 |
2009-11-12 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
CA2490758C
(en)
|
2002-07-15 |
2014-09-23 |
Genentech, Inc. |
Dosage form of recombinant humanized monoclonal antibody 2c4
|
ZA200500480B
(en)
|
2002-07-15 |
2006-10-25 |
Wyeth Corp |
Methods and compositions for modulating T helper (TH) cell development and function
|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
PT1523496E
(pt)
|
2002-07-18 |
2011-09-29 |
Merus B V |
Produção de misturas de anticorpos de forma recombinante
|
CA2496400A1
(en)
|
2002-09-09 |
2004-03-18 |
Dana-Farber Cancer Institute, Inc. |
Bh3 peptides and method of use thereof
|
HUE033623T2
(en)
|
2002-09-11 |
2017-12-28 |
Genentech Inc |
protein purification
|
EP2116551A1
(en)
|
2002-09-11 |
2009-11-11 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
AU2003270439B2
(en)
|
2002-09-11 |
2009-09-24 |
Genentech, Inc. |
Novel composition and methods for the treatment of immune related diseases
|
EP2444409A2
(en)
|
2002-09-16 |
2012-04-25 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
DE10244457A1
(de)
|
2002-09-24 |
2004-04-01 |
Johannes-Gutenberg-Universität Mainz |
Verfahren zur rationalen Mutagenese von alpha/beta T-Zell Rezeptoren und entsprechend mutierte MDM2-Protein spezifische alpha/beta T-Zell Rezeptoren
|
AU2003279084A1
(en)
|
2002-09-25 |
2004-04-19 |
Genentech, Inc. |
Novel compositions and methods for the treatment of psoriasis
|
US20060235208A1
(en)
*
|
2002-09-27 |
2006-10-19 |
Xencor, Inc. |
Fc variants with optimized properties
|
US9701754B1
(en)
|
2002-10-23 |
2017-07-11 |
City Of Hope |
Covalent disulfide-linked diabodies and uses thereof
|
EP2322200A3
(en)
|
2002-10-29 |
2011-07-27 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
AU2003287345A1
(en)
*
|
2002-10-31 |
2004-06-07 |
Genentech, Inc. |
Methods and compositions for increasing antibody production
|
CA2503748A1
(en)
|
2002-11-08 |
2004-05-27 |
Genentech, Inc. |
Compositions and methods for the treatment of natural killer cell related diseases
|
WO2004047728A2
(en)
|
2002-11-26 |
2004-06-10 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
US8084582B2
(en)
|
2003-03-03 |
2011-12-27 |
Xencor, Inc. |
Optimized anti-CD20 monoclonal antibodies having Fc variants
|
US20070275460A1
(en)
*
|
2003-03-03 |
2007-11-29 |
Xencor.Inc. |
Fc Variants With Optimized Fc Receptor Binding Properties
|
US8388955B2
(en)
*
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
CA2519241A1
(en)
|
2003-04-01 |
2004-11-11 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
AU2004229335C1
(en)
|
2003-04-04 |
2010-06-17 |
Genentech, Inc. |
High concentration antibody and protein formulations
|
JP2006522811A
(ja)
|
2003-04-09 |
2006-10-05 |
ジェネンテック・インコーポレーテッド |
TNFαインヒビターに対して不十分な反応を示す患者の自己免疫疾患治療法
|
US9051373B2
(en)
|
2003-05-02 |
2015-06-09 |
Xencor, Inc. |
Optimized Fc variants
|
US7348004B2
(en)
|
2003-05-06 |
2008-03-25 |
Syntonix Pharmaceuticals, Inc. |
Immunoglobulin chimeric monomer-dimer hybrids
|
PL2298347T3
(pl)
|
2003-05-06 |
2016-03-31 |
Bioverativ Therapeutics Inc |
Białka chimeryczne czynnika krzepnięcia do leczenia zaburzenia hemostazy
|
US20050037947A1
(en)
*
|
2003-05-06 |
2005-02-17 |
Bitonti Alan J. |
Inhibition of drug binding to serum albumin
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
WO2004106375A1
(en)
|
2003-05-30 |
2004-12-09 |
Merus Biopharmaceuticals B.V. I.O. |
Fab library for the preparation of anti vegf and anti rabies virus fabs
|
US9708410B2
(en)
|
2003-05-30 |
2017-07-18 |
Janssen Biotech, Inc. |
Anti-tissue factor antibodies and compositions
|
MXPA05012723A
(es)
|
2003-05-30 |
2006-02-08 |
Genentech Inc |
Tratamiento con anticuerpos anti-vgf.
|
AU2004251161A1
(en)
*
|
2003-05-30 |
2005-01-06 |
Genentech, Inc. |
Polypeptides that bind an anti-tissue factor antibody and uses thereof
|
ES2538469T3
(es)
|
2003-06-05 |
2015-06-22 |
Genentech, Inc. |
Terapia de combinación para trastornos de células B
|
US20050118181A1
(en)
|
2003-06-05 |
2005-06-02 |
Stapleton Jack T. |
GB virus C (hepatitis G virus) for the treatment of HIV
|
ATE425463T1
(de)
|
2003-06-06 |
2009-03-15 |
Genentech Inc |
Modulation der wechselwirkung zwischen hgf-beta- kette und c-met
|
US8597911B2
(en)
|
2003-06-11 |
2013-12-03 |
Chugai Seiyaku Kabushiki Kaisha |
Process for producing antibodies
|
WO2005042582A1
(ja)
*
|
2003-11-04 |
2005-05-12 |
Chugai Seiyaku Kabushiki Kaisha |
抗体の製造方法
|
NZ544924A
(en)
*
|
2003-06-27 |
2009-03-31 |
Biogen Idec Inc |
Modified binding molecules comprising connecting peptides
|
KR100835786B1
(ko)
|
2003-07-08 |
2008-06-09 |
제넨테크, 인크. |
Il-17a/f 이종 폴리펩티드 및 그의 치료 용도
|
AU2004261941B2
(en)
|
2003-07-25 |
2008-04-10 |
Amgen Inc. |
Antagonists and agonists of LDCAM and methods of use
|
SI1648940T1
(sl)
|
2003-07-28 |
2016-08-31 |
Genentech, Inc. |
Zmanjševanje izluževanja proteina A med afinitetno kromatografijo proteina A
|
JP2007501011A
(ja)
*
|
2003-08-01 |
2007-01-25 |
ジェネンテック・インコーポレーテッド |
制限多様性配列を有する結合型ポリペプチド
|
WO2005014818A1
(ja)
|
2003-08-08 |
2005-02-17 |
Perseus Proteomics Inc. |
癌高発現遺伝子
|
WO2005019258A2
(en)
|
2003-08-11 |
2005-03-03 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
WO2005027966A2
(en)
*
|
2003-09-05 |
2005-03-31 |
Genentech, Inc. |
Antibodies with altered effector functions
|
US8101720B2
(en)
|
2004-10-21 |
2012-01-24 |
Xencor, Inc. |
Immunoglobulin insertions, deletions and substitutions
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
CN1326881C
(zh)
*
|
2003-09-29 |
2007-07-18 |
中国人民解放军军事医学科学院基础医学研究所 |
一种三价双特异性抗体,其制备方法及用途
|
WO2005035753A1
(ja)
|
2003-10-10 |
2005-04-21 |
Chugai Seiyaku Kabushiki Kaisha |
機能蛋白質を代替する二重特異性抗体
|
DK2489364T3
(en)
|
2003-11-06 |
2015-03-02 |
Seattle Genetics Inc |
Monomethylvaline compounds conjugated to antibodies
|
JP2008504002A
(ja)
|
2003-11-12 |
2008-02-14 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
新生児Fcレセプター(FcRn)結合ポリペプチド改変体、ダイマーFc結合タンパク質、およびそれらに関連する方法
|
CA2747871C
(en)
|
2003-11-17 |
2018-04-10 |
Genentech, Inc. |
Compositions and methods for the treatment of tumor of hematopoietic origin
|
US7312320B2
(en)
|
2003-12-10 |
2007-12-25 |
Novimmune Sa |
Neutralizing antibodies and methods of use thereof
|
KR101195291B1
(ko)
|
2003-12-11 |
2012-10-26 |
제넨테크, 인크. |
C-met 이량체화 및 활성화를 억제하는 방법 및조성물
|
US20070281327A1
(en)
*
|
2003-12-12 |
2007-12-06 |
Kiyotaka Nakano |
Methods of Screening for Modified Antibodies With Agonistic Activities
|
EP1710255A4
(en)
*
|
2003-12-12 |
2008-09-24 |
Chugai Pharmaceutical Co Ltd |
MODIFIED ANTIBODIES RECOGNIZING A TRIMER OR LARGER RECEPTOR
|
US7371381B2
(en)
*
|
2003-12-12 |
2008-05-13 |
Amgen Inc. |
Anti-galanin antibodies and uses thereof
|
TW200530269A
(en)
*
|
2003-12-12 |
2005-09-16 |
Chugai Pharmaceutical Co Ltd |
Anti-Mpl antibodies
|
NZ547438A
(en)
*
|
2003-12-19 |
2010-01-29 |
Genentech Inc |
Monovalent antibody fragments useful as therapeutics
|
US20050249723A1
(en)
*
|
2003-12-22 |
2005-11-10 |
Xencor, Inc. |
Fc polypeptides with novel Fc ligand binding sites
|
US20050266425A1
(en)
*
|
2003-12-31 |
2005-12-01 |
Vaccinex, Inc. |
Methods for producing and identifying multispecific antibodies
|
CA2552750C
(en)
|
2004-01-07 |
2021-11-09 |
Chiron Corporation |
M-csf-specific monoclonal antibody and uses thereof
|
CA2554054C
(en)
|
2004-01-20 |
2013-06-04 |
Merus B.V. |
Mixtures of binding proteins
|
US20060122377A1
(en)
|
2004-02-19 |
2006-06-08 |
Genentech, Inc. |
CDR-repaired antibodies
|
WO2005087810A2
(en)
|
2004-03-08 |
2005-09-22 |
Zymogenetics, Inc. |
Dimeric fusion proteins and materials and methods for producing them
|
WO2005092925A2
(en)
*
|
2004-03-24 |
2005-10-06 |
Xencor, Inc. |
Immunoglobulin variants outside the fc region
|
RU2386638C2
(ru)
|
2004-03-31 |
2010-04-20 |
Дженентек, Инк. |
Гуманизированные анти-тфр-бета-антитела
|
US7794713B2
(en)
|
2004-04-07 |
2010-09-14 |
Lpath, Inc. |
Compositions and methods for the treatment and prevention of hyperproliferative diseases
|
US20150017671A1
(en)
|
2004-04-16 |
2015-01-15 |
Yaping Shou |
Methods for detecting lp-pla2 activity and inhibition of lp-pla2 activity
|
BRPI0509412A
(pt)
*
|
2004-04-16 |
2007-09-04 |
Genentech Inc |
método de tratamento de policondrite ou mononeurite multiplex em mamìferos e artigo industrializado
|
MXPA06011805A
(es)
*
|
2004-04-16 |
2006-12-15 |
Genentech Inc |
Metodo para aumentar agotamiento de celulas b.
|
AU2005249490B2
(en)
|
2004-06-01 |
2010-07-29 |
Genentech, Inc. |
Antibody drug conjugates and methods
|
EP3130349A1
(en)
|
2004-06-04 |
2017-02-15 |
Genentech, Inc. |
Method for treating multiple sclerosis
|
US7973134B2
(en)
|
2004-07-07 |
2011-07-05 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways
|
US20150010550A1
(en)
|
2004-07-15 |
2015-01-08 |
Xencor, Inc. |
OPTIMIZED Fc VARIANTS
|
JP4947717B2
(ja)
|
2004-07-20 |
2012-06-06 |
ジェネンテック, インコーポレイテッド |
アンジオポエチン様4タンパク質のインヒビター、組み合わせ、およびそれらの使用
|
US7846438B2
(en)
|
2004-08-03 |
2010-12-07 |
Biogen Idec Ma Inc. |
Methods of promoting neurite outgrowth with soluble TAJ polypeptides
|
DE602005020799D1
(de)
*
|
2004-08-05 |
2010-06-02 |
Genentech Inc |
Humanisierte anti-cmet-antagonisten
|
US7662926B2
(en)
*
|
2004-09-02 |
2010-02-16 |
Genentech, Inc. |
Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor
|
US20060204493A1
(en)
*
|
2004-09-02 |
2006-09-14 |
Genentech, Inc. |
Heteromultimeric molecules
|
US7655229B2
(en)
*
|
2004-09-02 |
2010-02-02 |
Chan Andrew C |
Anti-FC-gamma RIIB receptor antibody and uses therefor
|
KR101247908B1
(ko)
*
|
2004-09-02 |
2013-03-26 |
제넨테크, 인크. |
항-fc-감마 riib 수용체 항체 및 그의 용도
|
ES2377979T3
(es)
*
|
2004-09-03 |
2012-04-03 |
Genentech, Inc. |
Antagonistas anti-beta7 humanizados y utilizaciones para los mismos
|
US20060074225A1
(en)
*
|
2004-09-14 |
2006-04-06 |
Xencor, Inc. |
Monomeric immunoglobulin Fc domains
|
US7935790B2
(en)
|
2004-10-04 |
2011-05-03 |
Cell Singaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
NZ598502A
(en)
*
|
2004-10-21 |
2013-07-26 |
Genentech Inc |
Use of vegf antagonists in intraocular neovascular disease treatment
|
US8546543B2
(en)
|
2004-11-12 |
2013-10-01 |
Xencor, Inc. |
Fc variants that extend antibody half-life
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
CN102746404B
(zh)
|
2004-11-12 |
2016-01-20 |
赞科股份有限公司 |
对FcRn的结合被改变的Fc变体
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
US7807789B2
(en)
|
2004-12-21 |
2010-10-05 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
|
MY146381A
(en)
|
2004-12-22 |
2012-08-15 |
Amgen Inc |
Compositions and methods relating relating to anti-igf-1 receptor antibodies
|
WO2006074399A2
(en)
*
|
2005-01-05 |
2006-07-13 |
Biogen Idec Ma Inc. |
Multispecific binding molecules comprising connecting peptides
|
DK1841793T3
(da)
|
2005-01-07 |
2010-07-19 |
Diadexus Inc |
Ovr110-antistofsammensætninger og fremgangsmåder til anvendelse deraf
|
AU2006204791A1
(en)
*
|
2005-01-12 |
2006-07-20 |
Xencor, Inc |
Antibodies and Fc fusion proteins with altered immunogenicity
|
CN102580084B
(zh)
|
2005-01-21 |
2016-11-23 |
健泰科生物技术公司 |
Her抗体的固定剂量给药
|
US8029783B2
(en)
|
2005-02-02 |
2011-10-04 |
Genentech, Inc. |
DR5 antibodies and articles of manufacture containing same
|
AU2006214121B9
(en)
|
2005-02-15 |
2013-02-14 |
Duke University |
Anti-CD19 antibodies and uses in oncology
|
EP1871807B1
(en)
|
2005-02-18 |
2012-11-28 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against cxcr4 and methods of use thereof
|
SI1850874T1
(sl)
|
2005-02-23 |
2014-01-31 |
Genentech, Inc. |
Podaljšanje časa za napredovanje bolezni ali za preživetje pri pacientkah z rakom na jajčnikih ob uporabi pertuzumaba
|
TW200714289A
(en)
*
|
2005-02-28 |
2007-04-16 |
Genentech Inc |
Treatment of bone disorders
|
TW200642695A
(en)
*
|
2005-03-08 |
2006-12-16 |
Genentech Inc |
Methods for identifying tumors responsive to treatment with her dimerization inhibitors (HDIs)
|
WO2006106905A1
(ja)
*
|
2005-03-31 |
2006-10-12 |
Chugai Seiyaku Kabushiki Kaisha |
会合制御によるポリペプチド製造方法
|
US9493569B2
(en)
|
2005-03-31 |
2016-11-15 |
Chugai Seiyaku Kabushiki Kaisha |
Structural isomers of sc(Fv)2
|
PE20061324A1
(es)
|
2005-04-29 |
2007-01-15 |
Centocor Inc |
Anticuerpos anti-il-6, composiciones, metodos y usos
|
EP2221316A1
(en)
|
2005-05-05 |
2010-08-25 |
Duke University |
Anti-CD19 antibody therapy for autoimmune disease
|
RS54876B1
(sr)
|
2005-05-10 |
2016-10-31 |
Incyte Holdings Corp |
Modulatori indoleamina 2,3-dioksigenaze i metode za upotrebu istih
|
CA2608474C
(en)
|
2005-05-17 |
2019-11-12 |
University Of Connecticut |
Compositions and methods for immunomodulation in an organism
|
US7858843B2
(en)
|
2005-06-06 |
2010-12-28 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
WO2006132341A1
(ja)
*
|
2005-06-10 |
2006-12-14 |
Chugai Seiyaku Kabushiki Kaisha |
sc(Fv)2部位特異的変異体
|
CA2610987C
(en)
|
2005-06-10 |
2013-09-10 |
Chugai Seiyaku Kabushiki Kaisha |
Stabilizer for protein preparation comprising meglumine and use thereof
|
CN101262885B
(zh)
|
2005-06-10 |
2015-04-01 |
中外制药株式会社 |
含有sc(Fv)2的药物组合物
|
US7491391B2
(en)
|
2005-06-30 |
2009-02-17 |
Centocor, Inc. |
Anti-IL-23 antibodies, compositions, methods and uses
|
US8871720B2
(en)
|
2005-07-07 |
2014-10-28 |
Seattle Genetics, Inc. |
Monomethylvaline compounds having phenylalanine carboxy modifications at the C-terminus
|
AU2006269422B2
(en)
|
2005-07-07 |
2012-12-06 |
Seagen Inc. |
Monomethylvaline compounds having phenylalanine side-chain modifications at the C-terminus
|
EP2394661A1
(en)
|
2005-07-08 |
2011-12-14 |
Biogen Idec MA Inc. |
Sp35 antibodies and uses thereof
|
EP2311876A3
(en)
|
2005-07-28 |
2011-04-27 |
Novartis AG |
M-CSF-specific monoclonal antibody and uses thereof
|
JP5118037B2
(ja)
|
2005-08-09 |
2013-01-16 |
ザイモジェネティクス, インコーポレイテッド |
Taci融合分子を用いた異常細胞増殖の処置及び予防のための方法
|
ZA200801354B
(en)
|
2005-08-09 |
2009-08-26 |
Ares Trading Sa |
Methods for treating B-cell malignancies using TACI-lg fusion molecule
|
US7931902B2
(en)
|
2005-08-15 |
2011-04-26 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
WO2007024649A2
(en)
*
|
2005-08-19 |
2007-03-01 |
X-Cell Medical Incorporated |
Methods of treating and preventing acute myocardial infarction
|
WO2007027906A2
(en)
|
2005-08-31 |
2007-03-08 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in leukemia signaling pathways
|
EP1931709B1
(en)
*
|
2005-10-03 |
2016-12-07 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
US7422899B2
(en)
*
|
2005-10-05 |
2008-09-09 |
Biogen Idec Ma Inc. |
Antibodies to the human prolactin receptor
|
CA2625998C
(en)
|
2005-10-06 |
2015-12-01 |
Xencor, Inc. |
Optimized anti-cd30 antibodies
|
AR056142A1
(es)
|
2005-10-21 |
2007-09-19 |
Amgen Inc |
Metodos para generar el anticuerpo igg monovalente
|
EP1961065A4
(en)
|
2005-10-31 |
2009-11-11 |
Oncomed Pharm Inc |
COMPOSITIONS AND METHOD FOR DIAGNOSIS AND TREATMENT OF CANCER
|
EP1957531B1
(en)
|
2005-11-07 |
2016-04-13 |
Genentech, Inc. |
Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
|
KR20080082629A
(ko)
*
|
2005-11-10 |
2008-09-11 |
리셉터 바이오로직스 인크 |
간세포 성장인자 인트론 융합 단백질
|
MY149159A
(en)
|
2005-11-15 |
2013-07-31 |
Hoffmann La Roche |
Method for treating joint damage
|
CN101360826B
(zh)
|
2005-11-18 |
2014-04-30 |
格兰马克药品股份有限公司 |
抗α2整联蛋白抗体及它们的用途
|
CA2630432A1
(en)
|
2005-11-21 |
2007-07-19 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
WO2007064919A2
(en)
*
|
2005-12-02 |
2007-06-07 |
Genentech, Inc. |
Binding polypeptides with restricted diversity sequences
|
WO2007064911A1
(en)
*
|
2005-12-02 |
2007-06-07 |
Biogen Idec Inc. |
Anti-mouse cd20 antibodies and uses thereof
|
JP5808070B2
(ja)
*
|
2005-12-02 |
2015-11-10 |
ジェネンテック, インコーポレイテッド |
結合ポリペプチド及びその使用
|
CA2631961A1
(en)
|
2005-12-02 |
2007-11-08 |
Genentech, Inc. |
Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling relating to antibodies that bind to il-22
|
EP1973948B1
(en)
|
2005-12-15 |
2015-02-11 |
Genentech, Inc. |
Methods and compositions for targeting polyubiquitin
|
ES2622602T3
(es)
|
2005-12-29 |
2017-07-06 |
Janssen Biotech, Inc. |
Anticuerpos anti-IL-23 humanos, composiciones, procedimientos y usos
|
WO2007081879A2
(en)
|
2006-01-05 |
2007-07-19 |
Novartis Ag |
Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
|
SG10201400426XA
(en)
|
2006-01-12 |
2014-07-30 |
Alexion Pharma Inc |
Antibodies to ox-2/cd200 and uses thereof
|
US7803561B2
(en)
|
2006-02-06 |
2010-09-28 |
Rhode Island Hospital |
GPR30 estrogen receptor in breast cancers
|
EP2050335A1
(en)
|
2006-02-17 |
2009-04-22 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
EP1999253B1
(en)
*
|
2006-03-02 |
2019-05-22 |
Viacyte, Inc. |
Endocrine precursor cells, pancreatic hormone-expressing cells and methods of production
|
EP1999148B8
(en)
|
2006-03-06 |
2014-03-05 |
Medlmmune, LLC |
Humanized anti-cd22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
WO2007106769A2
(en)
|
2006-03-10 |
2007-09-20 |
Zymogenetics, Inc. |
Antibodies that bind both il-17a and il-17f and methods of using the same
|
EP2010569A4
(en)
|
2006-03-20 |
2009-09-09 |
Xoma Technology Ltd |
FOR GASTRIN SPECIFIC HUMAN ANTIBODIES, MATERIALS AND METHODS
|
CA2646329C
(en)
*
|
2006-03-20 |
2018-07-03 |
The Regents Of The University Of California |
Engineered anti-prostate stem cell antigen (psca) antibodies for cancer targeting
|
CN101437536A
(zh)
|
2006-03-23 |
2009-05-20 |
诺华有限公司 |
抗肿瘤细胞抗原抗体治疗
|
WO2007110205A2
(en)
*
|
2006-03-24 |
2007-10-04 |
Merck Patent Gmbh |
Engineered heterodimeric protein domains
|
US7566565B2
(en)
|
2006-03-24 |
2009-07-28 |
Syntonix Pharmaceuticals, Inc. |
PC5 as a factor IX propeptide processing enzyme
|
US11046784B2
(en)
|
2006-03-31 |
2021-06-29 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for controlling blood pharmacokinetics of antibodies
|
EP4218801A3
(en)
|
2006-03-31 |
2023-08-23 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody modification method for purifying bispecific antibody
|
WO2007123791A2
(en)
|
2006-03-31 |
2007-11-01 |
Dana-Farber Cancer Institute |
Methods of determining cellular chemosensitivity
|
US20090288176A1
(en)
|
2006-04-19 |
2009-11-19 |
Genentech, Inc. |
Novel Gene Disruptions, Compositions and Methods Relating Thereto
|
BRPI0711823A2
(pt)
|
2006-05-15 |
2012-01-17 |
Ares Trading Sa |
métodos para tratamento de doenças auto-imunes com uma molécula de fusão taci-ig
|
TWI523864B
(zh)
|
2006-05-30 |
2016-03-01 |
建南德克公司 |
抗體及免疫接合物及其用途
|
US7862812B2
(en)
|
2006-05-31 |
2011-01-04 |
Lpath, Inc. |
Methods for decreasing immune response and treating immune conditions
|
CA2655205A1
(en)
*
|
2006-06-12 |
2007-12-21 |
Receptor Biologix Inc. |
Pan-cell surface receptor- specific therapeutics
|
CN101505793A
(zh)
*
|
2006-06-22 |
2009-08-12 |
瓦西尼斯公司 |
用于治疗癌症的抗c35抗体
|
FR2902799B1
(fr)
|
2006-06-27 |
2012-10-26 |
Millipore Corp |
Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
|
CA2657934C
(en)
|
2006-07-19 |
2017-04-04 |
The Trustees Of The University Of Pennsylvania |
Wsx-1/p28 as a target for anti-inflammatory responses
|
JP5406027B2
(ja)
|
2006-08-04 |
2014-02-05 |
ノバルティス アーゲー |
EphB3特異的抗体およびその使用
|
US8586006B2
(en)
|
2006-08-09 |
2013-11-19 |
Institute For Systems Biology |
Organ-specific proteins and methods of their use
|
US7939636B2
(en)
|
2006-08-11 |
2011-05-10 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in c-Src signaling pathways
|
AU2007285976B2
(en)
|
2006-08-14 |
2011-08-18 |
Xencor, Inc |
Optimized antibodies that target CD19
|
KR101433544B1
(ko)
|
2006-08-18 |
2014-08-27 |
노바르티스 아게 |
Prlr 특이적 항체 및 그 용도
|
RU2009110154A
(ru)
|
2006-08-22 |
2010-09-27 |
Джи2 ИНФЛЕММЕЙШН ПТИ ЛТД (AU) |
АНТИТЕЛА ПРОТИВ C5aR С УЛУЧШЕННЫМИ СВОЙСТВАМИ
|
EP2423332A1
(en)
|
2006-08-25 |
2012-02-29 |
Oncotherapy Science, Inc. |
Prognostic markers and therapeutic targets for lung cancer
|
CA2660795C
(en)
|
2006-09-18 |
2014-11-18 |
Xencor, Inc. |
Optimized antibodies that target hm1.24
|
US20080076139A1
(en)
|
2006-09-21 |
2008-03-27 |
Sharat Singh |
Methods and compositions for detecting the activation states of multiple signal transducers in rare circulating cells
|
CA2664738C
(en)
|
2006-09-29 |
2017-03-07 |
Oncomed Pharmaceuticals, Inc. |
Compositions and methods for diagnosing and treating cancer
|
KR20090078349A
(ko)
*
|
2006-10-12 |
2009-07-17 |
제넨테크, 인크. |
림포톡신-알파에 대한 항체
|
GB0620705D0
(en)
|
2006-10-18 |
2006-11-29 |
Opsona Therapeutics |
Compounds for the modulation of toll-like receptor activity and assay methods for the identification of said compounds
|
SI2087002T1
(sl)
*
|
2006-10-27 |
2014-11-28 |
Lpath, Inc. |
Sestavki in postopki za vezavo sfingozin-1-fosfata
|
PT2061814E
(pt)
|
2006-10-27 |
2012-09-10 |
Genentech Inc |
Anticorpos e imunoconjugados e suas utilizações
|
US8614103B2
(en)
|
2006-10-27 |
2013-12-24 |
Lpath, Inc. |
Compositions and methods for treating sphingosine-1-phosphate (S1P) related ocular diseases and conditions
|
ES2437110T3
(es)
|
2006-11-14 |
2014-01-08 |
Genentech, Inc. |
Moduladores de la regeneración neuronal
|
WO2008067283A2
(en)
|
2006-11-27 |
2008-06-05 |
Diadexus, Inc. |
Ovr110 antibody compositions and methods of use
|
JP2010510794A
(ja)
|
2006-11-28 |
2010-04-08 |
ハナル ファーマシューティカル カンパニー リミテッド |
修飾型エリスロポエチンポリペプチド及びこの治療用用途
|
AU2007329307B2
(en)
|
2006-12-07 |
2012-08-02 |
Novartis Ag |
Antagonist antibodies against EphB3
|
US8163886B2
(en)
|
2006-12-21 |
2012-04-24 |
Emd Millipore Corporation |
Purification of proteins
|
US8569464B2
(en)
|
2006-12-21 |
2013-10-29 |
Emd Millipore Corporation |
Purification of proteins
|
US8362217B2
(en)
|
2006-12-21 |
2013-01-29 |
Emd Millipore Corporation |
Purification of proteins
|
WO2008079849A2
(en)
*
|
2006-12-22 |
2008-07-03 |
Genentech, Inc. |
Antibodies to insulin-like growth factor receptor
|
JP2011502954A
(ja)
*
|
2006-12-27 |
2011-01-27 |
ザ ジョンズ ホプキンス ユニバーシティー |
免疫応答を刺激する組成物および方法
|
US7989173B2
(en)
|
2006-12-27 |
2011-08-02 |
The Johns Hopkins University |
Detection and diagnosis of inflammatory disorders
|
JP2010515456A
(ja)
|
2007-01-09 |
2010-05-13 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
Sp35抗体およびその使用
|
EP2106439B1
(en)
*
|
2007-01-24 |
2014-11-12 |
The Regents of the University of Michigan |
Compositions and methods for treating and diagnosing pancreatic cancer
|
RU2009133784A
(ru)
|
2007-02-09 |
2011-03-20 |
Дженентек, Инк. (Us) |
АНТИ-Robo4-АНТИТЕЛА И ИХ ПРИМЕНЕНИЯ
|
WO2008100995A1
(en)
|
2007-02-14 |
2008-08-21 |
Vaccinex, Inc. |
Humanized anti-cd100 antibodies
|
US9023352B2
(en)
|
2007-02-20 |
2015-05-05 |
Tufts University |
Methods, compositions and kits for treating a subject using a recombinant heteromultimeric neutralizing binding protein
|
BRPI0807635A2
(pt)
|
2007-02-22 |
2014-06-03 |
Genentech Inc |
Métodos para detecção de doença inflamatória intestinal
|
AU2008223069B2
(en)
|
2007-03-02 |
2012-12-13 |
F. Hoffmann-La Roche Ag |
Predicting response to a HER dimerisation inhibitor based on low HER3 expression
|
US20090081659A1
(en)
|
2007-03-07 |
2009-03-26 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
WO2008118324A2
(en)
|
2007-03-26 |
2008-10-02 |
Macrogenics, Inc. |
Composition and method of treating cancer with an anti-uroplakin ib antibody
|
US20090068684A1
(en)
|
2007-03-26 |
2009-03-12 |
Cell Signaling Technology, Inc. |
Serine and threoninephosphorylation sites
|
CN104497143B
(zh)
|
2007-03-29 |
2020-08-25 |
健玛保 |
双特异性抗体及其制造方法
|
WO2008119566A2
(en)
*
|
2007-04-03 |
2008-10-09 |
Micromet Ag |
Cross-species-specific bispecific binders
|
US7807168B2
(en)
*
|
2007-04-10 |
2010-10-05 |
Vaccinex, Inc. |
Selection of human TNFα specific antibodies
|
US20080260738A1
(en)
|
2007-04-18 |
2008-10-23 |
Moore Margaret D |
Single chain fc, methods of making and methods of treatment
|
US7977462B2
(en)
|
2007-04-19 |
2011-07-12 |
Cell Signaling Technology, Inc. |
Tyrosine phosphorylation sites
|
EP1983003A3
(en)
|
2007-04-19 |
2009-03-11 |
Peter Hornbeck |
Tyrosine phosphorylation sites and antibodies specific for them
|
EP2145902A3
(en)
|
2007-04-19 |
2010-09-29 |
Peter Hornbeck |
Tyrosine phosphorylation sites and antibodies specific for them
|
WO2008134659A2
(en)
|
2007-04-27 |
2008-11-06 |
Zymogenetics, Inc. |
Antagonists to il-17a, il-17f, and il-23p19 and methods of use
|
US20090053831A1
(en)
|
2007-05-01 |
2009-02-26 |
Cell Signaling Technology, Inc. |
Tyrosine phosphorylation sites
|
US20080279851A1
(en)
|
2007-05-07 |
2008-11-13 |
Medlmmune, Llc |
Anti-icos antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
US20090252729A1
(en)
*
|
2007-05-14 |
2009-10-08 |
Farrington Graham K |
Single-chain Fc (scFc) regions, binding polypeptides comprising same, and methods related thereto
|
US8604172B2
(en)
|
2009-04-17 |
2013-12-10 |
Lpath, Inc. |
Humanized antibody compositions and methods for binding lysophosphatidic acid
|
AU2008260135A1
(en)
|
2007-05-30 |
2008-12-11 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
US9163091B2
(en)
|
2007-05-30 |
2015-10-20 |
Lpath, Inc. |
Compositions and methods for binding lysophosphatidic acid
|
EP2171090B1
(en)
|
2007-06-08 |
2013-04-03 |
Genentech, Inc. |
Gene expression markers of tumor resistance to her2 inhibitor treatment
|
US7580304B2
(en)
*
|
2007-06-15 |
2009-08-25 |
United Memories, Inc. |
Multiple bus charge sharing
|
SI2158315T1
(sl)
*
|
2007-06-25 |
2016-05-31 |
Esbatech, An Alcon Biomedical Research Unit Llc |
Postopki za spreminjanje protiteles in spremenjena protitelesa z izboljšanimi funkcionalnimi lastnostmi
|
CL2008001887A1
(es)
|
2007-06-29 |
2008-10-03 |
Amgen Inc |
Proteinas de union a antigeno que se unen al receptor activado por proteasas 2 (par-2); acido nucleico que las codifica; vector y celula huesped; metodo de produccion; y composicion que las comprende.
|
AU2008270972B2
(en)
|
2007-07-02 |
2013-10-24 |
Oncomed Pharmaceuticals, Inc. |
Compositions and methods for treating and diagnosing cancer
|
DE17196350T1
(de)
|
2007-07-09 |
2018-12-27 |
Genentech, Inc. |
Verhindern der disulfid-bindungsreduktion während der rekombinanten herstellung von polypeptiden
|
PE20140625A1
(es)
|
2007-07-16 |
2014-05-29 |
Genentech Inc |
ANTICUERPOS ANTI-CD79b E INMUNOCONJUGADOS HUMANIZADOS
|
EP2474557B1
(en)
|
2007-07-16 |
2014-08-20 |
Genentech, Inc. |
Anti-CD79b antibodies and immunoconjugates and methods of use
|
EP2185593B1
(en)
|
2007-07-25 |
2017-12-13 |
Alexion Pharmaceuticals, Inc. |
Compositions for treating autoimmune disease
|
EP2626371A1
(en)
|
2007-07-31 |
2013-08-14 |
MedImmune, LLC |
Multispecific epitope binding proteins and uses thereof
|
JP5659014B2
(ja)
|
2007-08-02 |
2015-01-28 |
ジリード バイオロジクス,インク. |
線維症、腫瘍浸潤、血管新生及び転移の治療及び診断のための方法及び組成物
|
MX2010001307A
(es)
|
2007-08-02 |
2010-07-30 |
Novimmune Sa |
Anticuerpos anti-proteína regulada con la activación, expresada y secretada por los linfocitos t normales y metodos de uso de los mismos.
|
EP2190987B1
(en)
*
|
2007-08-21 |
2012-11-14 |
MorphoSys AG |
Methods for the formation of disulphide bonds
|
EP2197491A4
(en)
*
|
2007-09-04 |
2011-01-12 |
Univ California |
HIGHAFFINE ANTI-PROSTATE STEM CELL ANTIGEN (PSCA) ANTIBODIES TO CANCER AND TO THE DETECTION OF CANCER
|
SI2202245T1
(sl)
|
2007-09-26 |
2016-10-28 |
Chugai Seiyaku Kabushiki Kaisha |
Postopek modificiranja izoelektrične točke protitelesa preko aminokislinske substitucije v CDR
|
ES2687808T3
(es)
|
2007-09-26 |
2018-10-29 |
Chugai Seiyaku Kabushiki Kaisha |
Región constante de anticuerpo modificado
|
EP2200631A1
(en)
|
2007-10-16 |
2010-06-30 |
Zymogenetics, Inc. |
Combination of blys inhibition and anti-cd 20 agents for treatment of autoimmune disease
|
US8361465B2
(en)
*
|
2007-10-26 |
2013-01-29 |
Lpath, Inc. |
Use of anti-sphingosine-1-phosphate antibodies in combination with chemotherapeutic agents
|
KR20160129099A
(ko)
|
2007-11-07 |
2016-11-08 |
제넨테크, 인크. |
미생물 질환의 치료를 위한 조성물 및 방법
|
US20110033476A1
(en)
*
|
2007-11-12 |
2011-02-10 |
Theraclone Sciences Inc. |
Compositions and methods for the therapy and diagnosis of influenza
|
US20090203043A1
(en)
|
2007-11-21 |
2009-08-13 |
Peter Hornbeck |
Protein phosphorylation by basophilic serine/threonine kinases in insulin signaling pathways
|
AU2008329529B2
(en)
|
2007-11-27 |
2015-02-19 |
The University Of British Columbia |
14-3-3 eta antibodies and uses thereof for the diagnosis and treatment of arthritis
|
JP5490714B2
(ja)
*
|
2007-11-28 |
2014-05-14 |
メディミューン,エルエルシー |
タンパク質製剤
|
MX2010005893A
(es)
|
2007-11-29 |
2011-03-04 |
Genentech Inc Star |
Marcadores de expresion genica para enfermedad inflamatoria de intestino.
|
TWI580694B
(zh)
|
2007-11-30 |
2017-05-01 |
建南德克公司 |
抗-vegf抗體
|
KR101643005B1
(ko)
|
2007-12-05 |
2016-07-28 |
추가이 세이야쿠 가부시키가이샤 |
항nr10 항체 및 그의 이용
|
US8242247B2
(en)
|
2007-12-21 |
2012-08-14 |
Hoffmann-La Roche Inc. |
Bivalent, bispecific antibodies
|
US20090162359A1
(en)
*
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
EP2261254A3
(en)
|
2007-12-21 |
2011-04-13 |
Amgen, Inc |
Anti-amyloid antibodies and uses thereof
|
AU2008341050B2
(en)
|
2007-12-26 |
2013-10-24 |
Vaccinex, Inc. |
Anti-C35 antibody combination therapies and methods
|
PL2235059T3
(pl)
|
2007-12-26 |
2015-08-31 |
Xencor Inc |
Warianty FC o zmodyfikowanym wiązaniu do FCRN
|
CA3023887A1
(en)
|
2007-12-27 |
2009-07-09 |
Abbott Laboratories |
Anti-t. cruzi antibodies and methods of use
|
EP2235064B1
(en)
|
2008-01-07 |
2015-11-25 |
Amgen Inc. |
Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
|
CA2965198C
(en)
|
2008-01-15 |
2021-02-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Markers of acute myeloid leukemia stem cells
|
EP2080770A1
(en)
*
|
2008-01-21 |
2009-07-22 |
MorphoSys AG |
Proteinaceous binding molecules comprising purification tags
|
WO2009094551A1
(en)
|
2008-01-25 |
2009-07-30 |
Amgen Inc. |
Ferroportin antibodies and methods of use
|
TWI472339B
(zh)
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
包含結合至her2結構域ii之抗體及其酸性變異體的組合物
|
RU2553566C2
(ru)
|
2008-01-31 |
2015-06-20 |
Дженентек, Инк. |
АНТИ-CD79b АНТИТЕЛА И ИММУНОКОНЪЮГАТЫ И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
WO2009108637A1
(en)
|
2008-02-25 |
2009-09-03 |
Prometheus Laboratories, Inc. |
Drug selection for breast cancer therapy using antibody-based arrays
|
WO2009111644A2
(en)
*
|
2008-03-05 |
2009-09-11 |
The Regents Of The University Of Michigan |
Compositions and methods for diagnosing and treating pancreatic cancer
|
CL2009000542A1
(es)
*
|
2008-03-06 |
2010-11-05 |
Genentech Inc |
Uso de un antagonista de c-met y egfr de formula general i para preparar un medicamento para tratar el cancer.
|
US20090226455A1
(en)
*
|
2008-03-06 |
2009-09-10 |
Genentech, Inc. |
Combination therapy with c-met and her antagonists
|
JP5544309B2
(ja)
|
2008-03-10 |
2014-07-09 |
セラクローン サイエンシーズ, インコーポレイテッド |
サイトメガロウイルス感染の治療および診断のための組成物および方法
|
KR20100131003A
(ko)
*
|
2008-03-31 |
2010-12-14 |
제넨테크, 인크. |
천식을 치료 및 진단하기 위한 조성물 및 방법
|
CA2719189C
(en)
|
2008-04-09 |
2020-08-04 |
Genentech, Inc. |
Novel compositions and methods for the treatment of immune related diseases
|
US10000568B2
(en)
|
2008-04-10 |
2018-06-19 |
Cell Signaling Technology, Inc. |
Compositions and methods for detecting EGFR in cancer
|
PL2275443T3
(pl)
|
2008-04-11 |
2016-05-31 |
Chugai Pharmaceutical Co Ltd |
Cząsteczka wiążąca antygen zdolna do wiązania dwóch lub więcej cząsteczek antygenu w sposób powtarzalny
|
JP2011519279A
(ja)
|
2008-05-01 |
2011-07-07 |
アムジエン・インコーポレーテツド |
抗ヘプシジン抗体及び使用の方法
|
BRPI0908665A2
(pt)
*
|
2008-05-16 |
2020-08-18 |
Genentech Inc |
método para a determinação da eficácia de um antagonista de integrina beta7 para o tratamento de um distúrbio inflamatório gastrointestinal, método de predição da responsividade de um paciente, método para a determinaçao da dosagem de um antagonista de integrina beta7, método para determinaçao do regime terapêutico de um antagonista de integrina beta7, método para predição de prognóstico de uma doença inflamatória intestinal, método de elaboração de um tratamento e método de identificação de uma população de linfócitos
|
WO2009147781A1
(ja)
|
2008-06-02 |
2009-12-10 |
国立大学法人東京大学 |
抗がん剤
|
WO2009151514A1
(en)
|
2008-06-11 |
2009-12-17 |
Millipore Corporation |
Stirred tank bioreactor
|
WO2009158432A2
(en)
|
2008-06-27 |
2009-12-30 |
Amgen Inc. |
Ang-2 inhibition to treat multiple sclerosis
|
MY171866A
(en)
|
2008-07-08 |
2019-11-05 |
Incyte Holdings Corp |
1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase
|
SI2307051T1
(sl)
|
2008-07-08 |
2015-04-30 |
Oncomed Pharmaceuticals, Inc. |
Notch-vezavna sredstva in antagonisti ter postopki njihove uporabe
|
CA2997870A1
(en)
|
2008-07-09 |
2010-01-14 |
Biogen Ma Inc. |
Compositions comprising antibodies to lingo or fragments thereof
|
ES2442024T3
(es)
|
2008-07-15 |
2014-02-07 |
Academia Sinica |
Matrices de glucano sobre portaobjetos de vidrio revestidos con aluminio de tipo PTFE y métodos relacionados
|
US20100069616A1
(en)
*
|
2008-08-06 |
2010-03-18 |
The Regents Of The University Of California |
Engineered antibody-nanoparticle conjugates
|
WO2010019702A2
(en)
|
2008-08-12 |
2010-02-18 |
Oncomed Pharmaceuticals, Inc. |
Ddr1-binding agents and methods of use thereof
|
AU2009288730B2
(en)
|
2008-08-25 |
2013-06-20 |
Amplimmune, Inc. |
Compositions of PD-1 antagonists and methods of use
|
US20110159023A1
(en)
|
2008-08-25 |
2011-06-30 |
Solomon Langermann |
Pd-1 antagonists and methods for treating infectious disease
|
CA2736799A1
(en)
|
2008-08-25 |
2010-03-11 |
Burnham Institute For Medical Research |
Conserved hemagglutinin epitope, antibodies to the epitope, and methods of use
|
US8790642B2
(en)
|
2008-08-29 |
2014-07-29 |
Genentech, Inc. |
Cross-reactive and bispecific anti-IL-17A/F antibodies
|
TW201014605A
(en)
|
2008-09-16 |
2010-04-16 |
Genentech Inc |
Methods for treating progressive multiple sclerosis
|
CN102264763B
(zh)
|
2008-09-19 |
2016-04-27 |
米迪缪尼有限公司 |
定向于dll4的抗体及其用途
|
TWI440469B
(zh)
|
2008-09-26 |
2014-06-11 |
Chugai Pharmaceutical Co Ltd |
Improved antibody molecules
|
MX2011002928A
(es)
|
2008-10-01 |
2011-04-11 |
Genentech Inc |
Anticuerpos anti-notch2 y metodos de uso.
|
KR20170091801A
(ko)
|
2008-10-02 |
2017-08-09 |
압테보 리서치 앤드 디벨롭먼트 엘엘씨 |
Cd86 길항제 다중-표적 결합 단백질
|
US8268314B2
(en)
|
2008-10-08 |
2012-09-18 |
Hoffmann-La Roche Inc. |
Bispecific anti-VEGF/anti-ANG-2 antibodies
|
EA032828B1
(ru)
*
|
2008-10-10 |
2019-07-31 |
Аптево Рисёрч Энд Девелопмент Ллс |
Иммунотерапевтические средства против комплекса tcr
|
SG195558A1
(en)
|
2008-10-14 |
2013-12-30 |
Genentech Inc |
Immunoglobulin variants and uses thereof
|
KR20110081862A
(ko)
|
2008-10-22 |
2011-07-14 |
제넨테크, 인크. |
축삭 변성의 조절
|
US8871202B2
(en)
|
2008-10-24 |
2014-10-28 |
Lpath, Inc. |
Prevention and treatment of pain using antibodies to sphingosine-1-phosphate
|
EP2346900A1
(en)
|
2008-10-29 |
2011-07-27 |
Wyeth LLC |
Methods for purification of single domain antigen binding molecules
|
CN104740631B
(zh)
|
2008-10-29 |
2019-04-16 |
阿布林克斯公司 |
单域抗原结合性分子的制剂
|
AU2009312532B2
(en)
|
2008-11-06 |
2013-05-16 |
Ichnos Sciences SA |
Treatment with anti-alpha2 integrin antibodies
|
US8298533B2
(en)
|
2008-11-07 |
2012-10-30 |
Medimmune Limited |
Antibodies to IL-1R1
|
DK2894165T3
(da)
|
2008-11-10 |
2023-03-20 |
Alexion Pharma Inc |
Fremgangsmåder og sammensætninger til behandling af komplementforbundne forstyrrelser
|
LT2356462T
(lt)
|
2008-11-11 |
2017-03-10 |
The Regents Of The University Of Michigan |
Anti-cxcr1 kompozicijos ir būdai
|
BRPI0921845A2
(pt)
|
2008-11-12 |
2019-09-17 |
Medimmune Llc |
formulação aquosa estéril estável, forma de dosagem unitária farmacêutica, seringa pré-carregada, e, métodos para tratar uma doença ou distúrbio, para tratar ou prevenir rejeição, para esgotar células t que expressam icos em um paciente humano, e para interromper arquitetura central germinal em um órgão linfóide secundário de um primata
|
BRPI0916092A2
(pt)
|
2008-11-25 |
2015-11-17 |
Genentech Inc |
"isoformas específicas de anticorpos anti-her4"
|
US8211434B2
(en)
*
|
2008-11-26 |
2012-07-03 |
Allergan, Inc. |
KLK-13 antibody inhibitor for treating dry eye
|
KR20110097923A
(ko)
*
|
2008-12-05 |
2011-08-31 |
엘파스, 인크. |
항-지질 항체 결정 구조를 이용한 항체 설계
|
US8401799B2
(en)
*
|
2008-12-05 |
2013-03-19 |
Lpath, Inc. |
Antibody design using anti-lipid antibody crystal structures
|
CN114835812A
(zh)
|
2008-12-09 |
2022-08-02 |
霍夫曼-拉罗奇有限公司 |
抗-pd-l1抗体及它们用于增强t细胞功能的用途
|
JP2012512244A
(ja)
|
2008-12-16 |
2012-05-31 |
イー・エム・デイー・ミリポア・コーポレイシヨン |
タンパク質の精製
|
EP2370561B1
(en)
|
2008-12-16 |
2019-08-07 |
EMD Millipore Corporation |
Stirred tank reactor and method
|
SG172219A1
(en)
|
2008-12-17 |
2011-07-28 |
Genentech Inc |
Hepatitis c virus combination therapy
|
WO2010075249A2
(en)
|
2008-12-22 |
2010-07-01 |
Genentech, Inc. |
A method for treating rheumatoid arthritis with b-cell antagonists
|
CN102264759B
(zh)
|
2008-12-23 |
2016-05-11 |
弗·哈夫曼-拉罗切有限公司 |
与蛋白a的结合改变的免疫球蛋白变体
|
JP2012513194A
(ja)
|
2008-12-23 |
2012-06-14 |
アストラゼネカ アクチボラグ |
α5β1に向けられた標的結合剤およびその使用
|
CN102341411A
(zh)
|
2008-12-31 |
2012-02-01 |
比奥根艾迪克Ma公司 |
抗-淋巴细胞毒素抗体
|
WO2010096394A2
(en)
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
JP5906090B2
(ja)
|
2009-02-17 |
2016-04-20 |
コーネル・リサーチ・ファンデーション・インコーポレイテッドCornell Research Foundation, Incorporated |
癌の診断のための方法およびキットならびに治療価の推定
|
SI3260136T1
(sl)
|
2009-03-17 |
2021-05-31 |
Theraclone Sciences, Inc. |
Humani imunodeficientni virus (HIV)-nevtralizirajoča protitelesa
|
JP5717624B2
(ja)
|
2009-03-19 |
2015-05-13 |
中外製薬株式会社 |
抗体定常領域改変体
|
TWI544077B
(zh)
|
2009-03-19 |
2016-08-01 |
Chugai Pharmaceutical Co Ltd |
Antibody constant region change body
|
CA2889453C
(en)
|
2009-03-20 |
2018-11-06 |
Amgen Inc. |
Carrier immunoglobulins and uses thereof
|
SG10201801337WA
(en)
|
2009-03-20 |
2018-03-28 |
Amgen Inc |
Alpha-4-Beta-7 Heterodimer Specific Antagonist Antibody
|
PE20120770A1
(es)
|
2009-03-25 |
2012-07-10 |
Genentech Inc |
ANTICUERPOS ANTI alfa5ß1 CON ACTIVIDAD SOBRE GLIOBLASTOMAS
|
MX347978B
(es)
|
2009-04-01 |
2017-05-22 |
Genentech Inc * |
Uso de los anticuerpos anti-il-17a y anti-il-17f en el tratamiento de la resistentes a insulina.
|
AU2010236787A1
(en)
|
2009-04-01 |
2011-11-10 |
Genentech, Inc. |
Anti-FcRH5 antibodies and immunoconjugates and methods of use
|
RU2598248C2
(ru)
|
2009-04-02 |
2016-09-20 |
Роше Гликарт Аг |
Полиспецифичные антитела, включающие антитела полной длины и одноцепочечные фрагменты fab
|
WO2010112194A1
(en)
|
2009-04-02 |
2010-10-07 |
F. Hoffmann-La Roche Ag |
Antigen-binding polypeptides and multispecific antibodies comprising them
|
CN102361884A
(zh)
|
2009-04-07 |
2012-02-22 |
罗氏格黎卡特股份公司 |
双特异性抗-ErbB-2/抗-c-Met抗体
|
EP2417156B1
(en)
|
2009-04-07 |
2015-02-11 |
Roche Glycart AG |
Trivalent, bispecific antibodies
|
PE20120550A1
(es)
|
2009-04-07 |
2012-05-21 |
Roche Glycart Ag |
ANTICUERPOS BIESPECIFICOS ANTI-ErbB-3/ANTI-C-MET
|
WO2010118243A2
(en)
|
2009-04-08 |
2010-10-14 |
Genentech, Inc. |
Use of il-27 antagonists to treat lupus
|
WO2010124163A2
(en)
*
|
2009-04-23 |
2010-10-28 |
Theraclone Sciences, Inc. |
Granulocyte-macrophage colony-stimulating factor (gm-csf) neutralizing antibodies
|
ES2708124T3
(es)
|
2009-04-27 |
2019-04-08 |
Oncomed Pharm Inc |
Procedimiento para preparar moléculas heteromultiméricas
|
MX2011011729A
(es)
|
2009-05-05 |
2012-04-10 |
Novimmune Sa |
Anticuerpo anti il-17f y metodos de uso de los mismos.
|
EA025245B1
(ru)
|
2009-05-08 |
2016-12-30 |
Вэксинекс, Инк. |
Антитела против cd100 и способы их применения
|
US8858948B2
(en)
|
2009-05-20 |
2014-10-14 |
Theraclone Sciences, Inc. |
Compositions and methods for the therapy and diagnosis of influenza
|
TW201100543A
(en)
|
2009-05-27 |
2011-01-01 |
Hoffmann La Roche |
Tri-or tetraspecific antibodies
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
AU2010264520A1
(en)
|
2009-06-23 |
2012-01-19 |
Alexion Pharmaceuticals, Inc. |
Bispecific antibodies that bind to complement proteins
|
MX342623B
(es)
|
2009-06-26 |
2016-10-06 |
Regeneron Pharma |
Anticuerpos biespecificos facilmente aislados con formato de inmunoglobulina original.
|
KR101962476B1
(ko)
|
2009-07-03 |
2019-03-26 |
아비펩 피티와이 리미티트 |
면역성 접합체 및 그 제조방법
|
MX2012000417A
(es)
|
2009-07-07 |
2012-02-08 |
Genentech Inc |
Diagnostico y tratamiento de enfermedades desmielinizantes autoinmunitarias.
|
AU2010273319B2
(en)
|
2009-07-15 |
2015-01-22 |
Nestec S.A. |
Drug selection for gastric cancer therapy using antibody-based arrays
|
EP2757160A3
(en)
|
2009-07-20 |
2014-07-30 |
Genentech, Inc. |
Gene expression markers for Crohn's disease
|
AR077595A1
(es)
|
2009-07-27 |
2011-09-07 |
Genentech Inc |
Tratamientos de combinacion
|
AU2010278959A1
(en)
|
2009-07-31 |
2012-02-02 |
Amgen Inc. |
Polypeptides that bind tissue inhibitor of metalloproteinase type three (TIMP-3), compositions and methods
|
ES2513292T3
(es)
|
2009-07-31 |
2014-10-24 |
Genentech, Inc. |
Inhibición de metástasis tumoral usando anticuerpos anti-G-CSF
|
WO2011031397A1
(en)
|
2009-08-06 |
2011-03-17 |
Genentech, Inc. |
Method to improve virus removal in protein purification
|
WO2011019620A1
(en)
|
2009-08-10 |
2011-02-17 |
Genentech, Inc. |
Antibodies with enhanced adcc function
|
US20110038871A1
(en)
|
2009-08-11 |
2011-02-17 |
Veena Viswanth |
Ccr2 inhibitors for treating conditions of the eye
|
KR20180114966A
(ko)
|
2009-08-11 |
2018-10-19 |
제넨테크, 인크. |
글루타민-비함유 세포 배양 배지에서의 단백질의 생성
|
BR112012003064B8
(pt)
|
2009-08-13 |
2021-05-25 |
Crucell Holland Bv |
anticorpo ou fragmento de ligação de antígeno do mesmo, combinação que os compreende, método de detecção de infecção por rsv, moléculas de ácido nucléico, e método de produção de um anticorpo ou fragmento de ligação de antígeno do mesmo
|
WO2011019622A1
(en)
|
2009-08-14 |
2011-02-17 |
Genentech, Inc. |
Cell culture methods to make antibodies with enhanced adcc function
|
EP2473523A2
(en)
|
2009-08-31 |
2012-07-11 |
Amplimmune, Inc. |
Methods and compositions for the inhibition of transplant rejection
|
MX2012002565A
(es)
|
2009-09-01 |
2012-05-29 |
Genentech Inc |
Purificacion de proteina mejorada a traves de una elucion de proteina a modificada.
|
US20110059111A1
(en)
|
2009-09-01 |
2011-03-10 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Mammalian receptors as targets for antibody and active vaccination therapy against mold infections
|
DK2473522T3
(en)
|
2009-09-02 |
2016-11-28 |
Genentech Inc |
Smoothened MUTANT AND METHODS OF USING THE SAME
|
US9493578B2
(en)
*
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
RU2573915C2
(ru)
*
|
2009-09-16 |
2016-01-27 |
Дженентек, Инк. |
Содержащие суперспираль и/или привязку белковые комплексы и их применение
|
CA2772670A1
(en)
|
2009-09-17 |
2011-03-24 |
F. Hoffmann-La Roche Ag |
Methods and compositions for diagnostics use in cancer patients
|
EP2481752B1
(en)
|
2009-09-24 |
2016-11-09 |
Chugai Seiyaku Kabushiki Kaisha |
Modified antibody constant regions
|
US8926976B2
(en)
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
AU2010298036B2
(en)
|
2009-09-25 |
2015-05-21 |
Xoma Technology Ltd. |
Screening methods
|
EP2483289B1
(en)
|
2009-10-02 |
2019-03-20 |
Biogen MA Inc. |
Methods of preventing and removing trisulfide bonds
|
US9096877B2
(en)
|
2009-10-07 |
2015-08-04 |
Macrogenics, Inc. |
Fc region-containing polypeptides that exhibit improved effector function due to alterations of the extent of fucosylation, and methods for their use
|
MX2012004303A
(es)
|
2009-10-15 |
2012-06-25 |
Genentech Inc |
Factores de crecimiento de fibroblasto quimericos con especificacion de receptor alterada.
|
WO2011047383A1
(en)
|
2009-10-16 |
2011-04-21 |
Oncomed Pharmaceuticals, Inc. |
Therapeutic combination and methods of treatment with a dll4 antagonist and an anti-hypertensive agent
|
JP5889794B2
(ja)
|
2009-10-19 |
2016-03-22 |
ジェネンテック, インコーポレイテッド |
肝細胞増殖因子アクチベーターの調節
|
WO2011050069A1
(en)
|
2009-10-20 |
2011-04-28 |
Prometheus Laboratories Inc. |
Proximity-mediated assays for detecting oncogenic fusion proteins
|
KR20120105446A
(ko)
|
2009-10-22 |
2012-09-25 |
제넨테크, 인크. |
대식세포-자극 단백질의 헵신 활성화를 조정하기 위한 방법 및 조성물
|
SG10201406763WA
(en)
|
2009-10-22 |
2014-11-27 |
Genentech Inc |
Modulation of axon degeneration
|
TW201120210A
(en)
|
2009-11-05 |
2011-06-16 |
Hoffmann La Roche |
Glycosylated repeat-motif-molecule conjugates
|
AU2010321832B2
(en)
|
2009-11-20 |
2014-08-14 |
Amgen Inc. |
Anti-Orai1 antigen binding proteins and uses thereof
|
AU2010321720B2
(en)
|
2009-11-23 |
2017-03-02 |
Amgen Inc. |
Monomeric antibody Fc
|
CA2992770A1
(en)
|
2009-11-24 |
2011-06-03 |
Medimmune Limited |
Targeted binding agents against b7-h1
|
NZ599707A
(en)
|
2009-11-30 |
2014-07-25 |
Genentech Inc |
Antibodies for treating and diagnosing tumors expressing slc34a2 (tat211 = seqid2 )
|
US10087236B2
(en)
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
US11377485B2
(en)
|
2009-12-02 |
2022-07-05 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
CA2782333C
(en)
|
2009-12-02 |
2019-06-04 |
Imaginab, Inc. |
J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use
|
RU2016105962A
(ru)
|
2009-12-04 |
2018-11-23 |
Дженентек, Инк. |
Мультиспецифические антитела, аналоги антител, композиции и способы
|
TWI505836B
(zh)
|
2009-12-11 |
2015-11-01 |
Genentech Inc |
抗-vegf-c抗體及其使用方法
|
CA2783846C
(en)
|
2009-12-21 |
2021-01-19 |
Genentech, Inc. |
Antibody formulation
|
KR101961495B1
(ko)
|
2009-12-23 |
2019-03-22 |
아비펩 피티와이 리미티트 |
면역-컨쥬게이트 및 그 제조방법 2
|
AR079704A1
(es)
|
2009-12-23 |
2012-02-15 |
Genentech Inc |
Anticuerpos anti-bv8 y sus usos
|
DK2519542T3
(en)
|
2009-12-28 |
2019-01-14 |
Onco Therapy Science Inc |
ANTI-CDH3 ANTIBODIES AND APPLICATIONS THEREOF.
|
JP5856073B2
(ja)
*
|
2009-12-29 |
2016-02-09 |
エマージェント プロダクト デベロップメント シアトル, エルエルシー |
Ron結合構築体およびその使用方法
|
CN102958534B
(zh)
|
2010-01-13 |
2014-11-05 |
昂考梅德药品有限公司 |
Notch1结合剂及其使用方法
|
WO2011091078A2
(en)
|
2010-01-19 |
2011-07-28 |
Xencor, Inc. |
Antibody fc variants with enhanced complement activity
|
US9796788B2
(en)
|
2010-02-08 |
2017-10-24 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|
US20130045492A1
(en)
|
2010-02-08 |
2013-02-21 |
Regeneron Pharmaceuticals, Inc. |
Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
|
NZ719253A
(en)
|
2010-02-08 |
2022-08-26 |
Regeneron Pharma |
Common light chain mouse
|
CN102933231B
(zh)
|
2010-02-10 |
2015-07-29 |
伊缪诺金公司 |
Cd20抗体及其用途
|
KR20120117931A
(ko)
|
2010-02-12 |
2012-10-24 |
온코메드 파마슈티칼스, 인크. |
폴리펩타이드를 발현하는 세포를 확인 및 분리하는 방법
|
CN102892779B
(zh)
|
2010-02-18 |
2016-12-21 |
基因泰克公司 |
神经调节蛋白拮抗剂及其在治疗癌症中的用途
|
WO2011106297A2
(en)
|
2010-02-23 |
2011-09-01 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
CN102933604B
(zh)
|
2010-02-23 |
2016-04-06 |
赛诺菲 |
抗-α2整联蛋白抗体及其用途
|
KR101637138B1
(ko)
|
2010-02-24 |
2016-07-06 |
이뮤노젠 아이엔씨 |
엽산염 수용체 1 항체와 면역접합체 및 이들의 용도
|
WO2011106723A2
(en)
*
|
2010-02-26 |
2011-09-01 |
Lpath, Inc. |
Anti-paf antibodies
|
WO2011107989A1
(en)
*
|
2010-03-01 |
2011-09-09 |
Lostam Biopharmaceuticals Ltd |
Improved therapeutic antibodies against flagellated pseudomonas aeruginosa
|
WO2011108714A1
(ja)
|
2010-03-04 |
2011-09-09 |
中外製薬株式会社 |
抗体定常領域改変体
|
US8802091B2
(en)
|
2010-03-04 |
2014-08-12 |
Macrogenics, Inc. |
Antibodies reactive with B7-H3 and uses thereof
|
CN106279416B
(zh)
|
2010-03-04 |
2019-08-30 |
宏观基因有限公司 |
与b7-h3反应性的抗体、其免疫学活性片段及其用途
|
CN106046159B
(zh)
|
2010-03-12 |
2020-06-16 |
德彪发姆国际有限公司 |
Cd37结合分子及其免疫缀合物
|
KR101899835B1
(ko)
|
2010-03-24 |
2018-09-19 |
제넨테크, 인크. |
항-lrp6 항체
|
TW201138821A
(en)
|
2010-03-26 |
2011-11-16 |
Roche Glycart Ag |
Bispecific antibodies
|
US10745467B2
(en)
|
2010-03-26 |
2020-08-18 |
The Trustees Of Dartmouth College |
VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
|
CA3079122A1
(en)
|
2010-03-26 |
2011-09-29 |
Trustees Of Dartmouth College |
Vista regulatory t cell mediator protein, vista binding agents and use thereof
|
US20150231215A1
(en)
|
2012-06-22 |
2015-08-20 |
Randolph J. Noelle |
VISTA Antagonist and Methods of Use
|
AR080794A1
(es)
|
2010-03-26 |
2012-05-09 |
Hoffmann La Roche |
Anticuerpos bivalentes biespecificos anti- vegf/ anti-ang-2
|
BR112012024786A2
(pt)
|
2010-03-30 |
2017-01-10 |
Janssen Biotech Inc |
anticorpos humanizados il-25
|
ES2566602T3
(es)
|
2010-04-09 |
2016-04-14 |
Aveo Pharmaceuticals, Inc. |
Anticuerpos anti-ErbB3
|
US20130101590A1
(en)
|
2010-04-09 |
2013-04-25 |
Heather A. Arnett |
Btnl9 proteins, nucleic acids, and antibodies and uses thereof
|
WO2011130332A1
(en)
|
2010-04-12 |
2011-10-20 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
CN103097417B
(zh)
|
2010-04-20 |
2019-04-09 |
根马布股份公司 |
含异二聚体抗体fc的蛋白及其制备方法
|
AU2013203221B2
(en)
*
|
2010-04-20 |
2016-06-02 |
Genmab A/S |
Heterodimeric antibody FC-containing proteins and methods for production thereof
|
JP2019048814A
(ja)
*
|
2010-04-20 |
2019-03-28 |
ゲンマブ エー/エス |
ヘテロ二量体抗体Fc含有タンパク質およびその産生方法
|
WO2011133931A1
(en)
|
2010-04-22 |
2011-10-27 |
Genentech, Inc. |
Use of il-27 antagonists for treating inflammatory bowel disease
|
EP2560683B2
(en)
*
|
2010-04-23 |
2022-07-20 |
F. Hoffmann-La Roche AG |
Production of heteromultimeric proteins
|
SI2563813T1
(sl)
|
2010-04-30 |
2015-12-31 |
Alexion Pharmaceuticals, Inc. |
Protitelesa anti-C5A in postopki uporabe protiteles
|
WO2011135040A1
(en)
|
2010-04-30 |
2011-11-03 |
F. Hoffmann-La Roche Ag |
Fluorescent antibody fusion protein, its production and use
|
MX2012012743A
(es)
|
2010-05-03 |
2012-11-23 |
Genentech Inc |
Composiciones y metodos utiles para reducir la viscosidad de formulaciones que contienen proteina.
|
CN107090045A
(zh)
|
2010-05-03 |
2017-08-25 |
霍夫曼-拉罗奇有限公司 |
用于肿瘤诊断和治疗的组合物和方法
|
CA2798432A1
(en)
|
2010-05-06 |
2011-11-10 |
Novartis Ag |
Compositions and methods of use for therapeutic low density lipoprotein -related protein 6 (lrp6) antibodies
|
CN103237811A
(zh)
|
2010-05-06 |
2013-08-07 |
诺瓦提斯公司 |
用于治疗性低密度脂蛋白相关蛋白质6(lrp6)多价抗体的组合物及使用方法
|
JP6022444B2
(ja)
*
|
2010-05-14 |
2016-11-09 |
ライナット ニューロサイエンス コーポレイション |
ヘテロ二量体タンパク質ならびにそれを生産および精製するための方法
|
US8691918B2
(en)
|
2010-05-17 |
2014-04-08 |
Emd Millipore Corporation |
Stimulus responsive polymers for the purification of biomolecules
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
MY161534A
(en)
|
2010-05-25 |
2017-04-28 |
Genentech Inc |
Methods of purifying polypeptides
|
WO2011147834A1
(en)
|
2010-05-26 |
2011-12-01 |
Roche Glycart Ag |
Antibodies against cd19 and uses thereof
|
CN103154035B
(zh)
|
2010-05-27 |
2017-05-10 |
根马布股份公司 |
针对her2的单克隆抗体
|
ES2599412T3
(es)
|
2010-05-28 |
2017-02-01 |
F. Hoffmann-La Roche Ag |
Disminución del nivel de lactato y aumento de la producción de polipéptidos regulando por disminución la expresión de la lactato deshidrogenasa y de la piruvato deshidrogenasa quinasa
|
NZ602840A
(en)
|
2010-06-03 |
2014-11-28 |
Genentech Inc |
Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
|
US20110311527A1
(en)
|
2010-06-16 |
2011-12-22 |
Allergan, Inc. |
IL23p19 ANTIBODY INHIBITOR FOR TREATING OCULAR AND OTHER CONDITIONS
|
CA2794731C
(en)
|
2010-06-18 |
2019-03-19 |
Genentech, Inc. |
Anti-axl antibodies and methods of use
|
US9315585B2
(en)
|
2010-06-19 |
2016-04-19 |
Memorial Sloan Kettering Cancer Center |
Anti-GD2 antibodies
|
CA2803588A1
(en)
|
2010-06-22 |
2011-12-29 |
The Regents Of The University Of Colorado, A Body Corporate |
Antibodies to the c3d fragment of complement component 3
|
WO2011161119A1
(en)
|
2010-06-22 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Antibodies against insulin-like growth factor i receptor and uses thereof
|
WO2011161189A1
(en)
|
2010-06-24 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Anti-hepsin antibodies and methods of use
|
US20130209463A1
(en)
|
2010-06-30 |
2013-08-15 |
Compugen Ltd. |
Polypeptides and uses thereof as a drug for treatment of multiple sclerosis, rheumatoid arthritis and other autoimmune disorders
|
US8735548B2
(en)
|
2010-06-30 |
2014-05-27 |
Amgen Inc. |
Antibodies which bind to SCNN1A/TNFRSF1A fusion proteins and methods of use thereof
|
JP5744196B2
(ja)
|
2010-07-09 |
2015-07-08 |
クルセル ホランド ベー ヴェー |
抗ヒト呼吸器多核体ウイルス(rsv)抗体および使用の方法
|
WO2012006503A1
(en)
|
2010-07-09 |
2012-01-12 |
Genentech, Inc. |
Anti-neuropilin antibodies and methods of use
|
US20120100166A1
(en)
|
2010-07-15 |
2012-04-26 |
Zyngenia, Inc. |
Ang-2 Binding Complexes and Uses Thereof
|
CN108314733A
(zh)
|
2010-07-16 |
2018-07-24 |
埃博灵克斯股份有限公司 |
修饰的单结构域抗原结合分子及其应用
|
CN103270418A
(zh)
|
2010-07-19 |
2013-08-28 |
霍夫曼-拉罗奇有限公司 |
鉴定响应抗癌疗法的可能性升高的患者的方法
|
CN103109189A
(zh)
|
2010-07-19 |
2013-05-15 |
霍夫曼-拉罗奇有限公司 |
鉴定响应抗癌疗法的可能性升高的患者的方法
|
WO2012009760A1
(en)
|
2010-07-20 |
2012-01-26 |
Cephalon Australia Pty Ltd |
Anti-il-23 heterodimer specific antibodies
|
WO2012010582A1
(en)
|
2010-07-21 |
2012-01-26 |
Roche Glycart Ag |
Anti-cxcr5 antibodies and methods of use
|
CA2806252C
(en)
|
2010-07-29 |
2019-05-14 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
RU2013106216A
(ru)
|
2010-08-03 |
2014-09-10 |
Ф. Хоффманн-Ля Рош Аг |
Биомаркеры хронической лимфоцитарной лейкемии
|
WO2012019024A2
(en)
|
2010-08-04 |
2012-02-09 |
Immunogen, Inc. |
Her3-binding molecules and immunoconjugates thereof
|
JP2013541937A
(ja)
|
2010-08-05 |
2013-11-21 |
エフ.ホフマン−ラ ロシュ アーゲー |
抗mhc抗体−抗ウイルス性サイトカイン融合タンパク質
|
WO2012019061A2
(en)
|
2010-08-05 |
2012-02-09 |
Stem Centrx, Inc. |
Novel effectors and methods of use
|
JP2013540701A
(ja)
|
2010-08-12 |
2013-11-07 |
セラクローン サイエンシーズ, インコーポレイテッド |
抗赤血球凝集素抗体組成物およびその使用方法
|
EP2420250A1
(en)
|
2010-08-13 |
2012-02-22 |
Universitätsklinikum Münster |
Anti-Syndecan-4 antibodies
|
LT2603530T
(lt)
|
2010-08-13 |
2018-01-25 |
Roche Glycart Ag |
Anti-fap antikūnai ir jų naudojimo metodai
|
WO2012021773A1
(en)
|
2010-08-13 |
2012-02-16 |
Genentech, Inc. |
Antibodies to il-1beta and il-18, for treatment of disease
|
RU2584597C2
(ru)
|
2010-08-13 |
2016-05-20 |
Рош Гликарт Аг |
Антитела против а2 тенасцина с и способы их применения
|
CN105440134A
(zh)
|
2010-08-16 |
2016-03-30 |
安姆根公司 |
结合肌肉生长抑制素的抗体、组合物和方法
|
WO2012022734A2
(en)
|
2010-08-16 |
2012-02-23 |
Medimmune Limited |
Anti-icam-1 antibodies and methods of use
|
NZ604510A
(en)
|
2010-08-17 |
2013-10-25 |
Csl Ltd |
Dilutable biocidal compositions and methods of use
|
CN103068847B
(zh)
*
|
2010-08-24 |
2019-05-07 |
罗切格利卡特公司 |
可活化的双特异性抗体
|
WO2012025530A1
(en)
|
2010-08-24 |
2012-03-01 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies comprising a disulfide stabilized - fv fragment
|
AR082518A1
(es)
|
2010-08-25 |
2012-12-12 |
Hoffmann La Roche |
Anticuerpos contra il-18r1 y usos de los mismos
|
PE20140190A1
(es)
|
2010-08-27 |
2014-02-10 |
Stem Centrx Inc |
Moduladores de proteinas notum y metodos de uso
|
EP2611465A4
(en)
|
2010-08-31 |
2014-06-04 |
Theraclone Sciences Inc |
NEUTRALIZING ANTI-VIRUS ANTIBODIES FOR HUMAN IMMUNODEFICIENCY (HIV)
|
DK2612151T3
(en)
|
2010-08-31 |
2017-10-02 |
Genentech Inc |
BIOMARKETS AND METHODS OF TREATMENT
|
SG188285A1
(en)
|
2010-09-02 |
2013-04-30 |
Vaccinex Inc |
Anti-cxcl13 antibodies and methods of using the same
|
US9458231B2
(en)
|
2010-09-03 |
2016-10-04 |
Stemcentrx, Inc. |
Modulators and methods of use
|
US8551479B2
(en)
|
2010-09-10 |
2013-10-08 |
Oncomed Pharmaceuticals, Inc. |
Methods for treating melanoma
|
US8999335B2
(en)
|
2010-09-17 |
2015-04-07 |
Compugen Ltd. |
Compositions and methods for treatment of drug resistant multiple myeloma
|
CA2814780C
(en)
|
2010-09-22 |
2017-05-16 |
Amgen Inc. |
Carrier immunoglobulins and uses thereof
|
US8481680B2
(en)
|
2010-10-05 |
2013-07-09 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
AR083546A1
(es)
|
2010-10-25 |
2013-03-06 |
Genentech Inc |
Tratamiento de inflamacion gastrointestinal, soriasis y asma
|
JP5828901B2
(ja)
|
2010-10-29 |
2015-12-09 |
イミュノジェン, インコーポレイテッド |
新規egfr結合分子およびその免疫抱合体
|
CN105399831A
(zh)
|
2010-10-29 |
2016-03-16 |
伊缪诺金公司 |
非拮抗性egfr结合分子及其免疫偶联物
|
EP2635674A4
(en)
|
2010-11-05 |
2014-11-05 |
Transbio Ltd |
MARKERS FOR ENDOTHELIAL STORAGE CELLS AND USES THEREOF
|
AU2011325833C1
(en)
*
|
2010-11-05 |
2017-07-13 |
Zymeworks Bc Inc. |
Stable heterodimeric antibody design with mutations in the Fc domain
|
CA2817015A1
(en)
|
2010-11-09 |
2012-05-18 |
Altimab Therapeutics, Inc. |
Protein complexes for antigen binding and methods of use
|
ES2607086T3
(es)
|
2010-11-10 |
2017-03-29 |
F. Hoffmann-La Roche Ag |
Métodos y composiciones para la inmunoterapia de enfermedades neuronales
|
US9511151B2
(en)
|
2010-11-12 |
2016-12-06 |
Uti Limited Partnership |
Compositions and methods for the prevention and treatment of cancer
|
KR101398363B1
(ko)
|
2010-11-17 |
2014-05-22 |
추가이 세이야쿠 가부시키가이샤 |
혈액응고 제viii 인자의 기능을 대체하는 기능을 갖는 다중특이성 항원 결합 분자
|
EP2643353A1
(en)
|
2010-11-24 |
2013-10-02 |
Novartis AG |
Multispecific molecules
|
WO2012071436A1
(en)
|
2010-11-24 |
2012-05-31 |
Genentech, Inc. |
Method of treating autoimmune inflammatory disorders using il-23r loss-of-function mutants
|
CA2818173C
(en)
|
2010-11-30 |
2022-05-03 |
Genentech, Inc. |
Low affinity blood brain barrier receptor antibodies and uses therefor
|
MX365235B
(es)
|
2010-11-30 |
2019-05-28 |
Chugai Pharmaceutical Co Ltd |
Molécula de unión a antígeno capaz de unir repetidamente a la pluralidad de moléculas de antígeno.
|
PL2647707T3
(pl)
|
2010-11-30 |
2019-02-28 |
Chugai Seiyaku Kabushiki Kaisha |
Środek terapeutyczny wywołujący cytotoksyczność
|
BR112013014321A2
(pt)
|
2010-12-08 |
2019-09-24 |
Stem Centrx Inc |
moduladores inovadores e métodos de uso
|
CN112168962A
(zh)
|
2010-12-16 |
2021-01-05 |
弗·哈夫曼-拉罗切有限公司 |
与th2抑制相关的诊断和治疗
|
KR20140014116A
(ko)
|
2010-12-20 |
2014-02-05 |
제넨테크, 인크. |
항-메소텔린 항체 및 면역접합체
|
AU2011348232A1
(en)
|
2010-12-22 |
2013-07-18 |
Genentech, Inc. |
Anti-PCSK9 antibodies and methods of use
|
KR20140002711A
(ko)
|
2010-12-23 |
2014-01-08 |
네스텍 소시에테아노님 |
항체-기반 어레이를 사용한 악성 암 치료를 위한 약물 선별법
|
JP5766296B2
(ja)
|
2010-12-23 |
2015-08-19 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用
|
GB2559498B
(en)
|
2011-01-10 |
2018-10-24 |
Univ Michigan Regents |
Stem cell factor inhibitor
|
KR20140016262A
(ko)
|
2011-01-14 |
2014-02-07 |
레드우드 바이오사이언스 인코포레이티드 |
알데하이드-태깅된 면역글로불린 폴리펩타이드 및 이의 사용 방법
|
CN103649126B
(zh)
|
2011-01-19 |
2016-11-09 |
菲卢马克斯制药公司 |
用于调节铁稳态的组合物及其使用方法
|
CA2825894C
(en)
|
2011-02-02 |
2021-11-30 |
Amgen Inc. |
Prognosis of cancer using a circulating biomarker
|
US9447187B2
(en)
|
2011-02-03 |
2016-09-20 |
Alexion Pharmaceuticals, Inc. |
Use of an anti-CD200 antibody for prolonging the survival of allografts
|
MX355255B
(es)
|
2011-02-04 |
2018-04-11 |
Genentech Inc |
Variantes de fc y métodos para su producción.
|
US10689447B2
(en)
|
2011-02-04 |
2020-06-23 |
Genentech, Inc. |
Fc variants and methods for their production
|
SG192673A1
(en)
|
2011-02-10 |
2013-09-30 |
Roche Glycart Ag |
Mutant interleukin-2 polypeptides
|
BR112013020743A2
(pt)
|
2011-02-14 |
2016-10-18 |
Theraclone Sciences Inc |
composições e métodos para a terapia e diagnóstico de influenza
|
SA112330278B1
(ar)
|
2011-02-18 |
2015-10-09 |
ستيم سينتركس، انك. |
مواد ضابطة جديدة وطرق للاستخدام
|
MX342034B
(es)
|
2011-02-28 |
2016-09-12 |
Hoffmann La Roche |
Proteinas monovalentes que se unen a antigenos.
|
EP2681239B8
(en)
|
2011-02-28 |
2015-09-09 |
F. Hoffmann-La Roche AG |
Antigen binding proteins
|
AU2012222833B2
(en)
|
2011-03-03 |
2017-03-16 |
Zymeworks Inc. |
Multivalent heteromultimer scaffold design and constructs
|
WO2012119989A2
(en)
|
2011-03-04 |
2012-09-13 |
Oryzon Genomics, S.A. |
Methods and antibodies for the diagnosis and treatment of cancer
|
JP2014515598A
(ja)
|
2011-03-10 |
2014-07-03 |
エイチシーオー アンティボディ, インク. |
二重特異性三鎖抗体様分子
|
WO2012122512A1
(en)
|
2011-03-10 |
2012-09-13 |
Hco Antibody, Inc. |
Recombinant production of mixtures of single chain antibodies
|
EP2686016B1
(en)
|
2011-03-14 |
2019-05-01 |
Cellmid Limited |
Antibody recognizing n-domain of midkine
|
JP2014509591A
(ja)
|
2011-03-15 |
2014-04-21 |
セラクローン サイエンシーズ, インコーポレイテッド |
インフルエンザの治療および診断のための組成物および方法
|
AU2012229048B2
(en)
|
2011-03-16 |
2016-01-21 |
Amgen Inc |
Fc variants
|
BR112013023653A2
(pt)
|
2011-03-17 |
2016-12-13 |
Univ Ramot |
anticorpo biespecífico, método de preparação do anticorpo, e composição farmacêutica
|
BR112013023918A2
(pt)
|
2011-03-25 |
2016-12-13 |
Glenmark Pharmaceuticals Sa |
imunoglobulina hetero-dimérica ou fragmento hetero-dimérico da mesma, método para produzir uma imunoglobulina hetero-dimérica ou fragmento hetero-dimérico da mesma, método para construir uma interface proteína-proteína de um domínio de uma proteína de múltiplos domínios e uso de um domínio doador de um primeiro e de um segundo membro de uma super-família de imunoglobulina de ocorrência natural
|
RU2607014C2
(ru)
|
2011-03-29 |
2017-01-10 |
Рош Гликарт Аг |
Fc варианты антитела
|
AU2012237287B2
(en)
|
2011-03-30 |
2016-09-08 |
Ablynx Nv |
Methods of treating immune disorders with single domain antibodies against TNF-alpha
|
DK2698431T3
(da)
|
2011-03-30 |
2020-11-30 |
Chugai Pharmaceutical Co Ltd |
Opretholdelse af antigen-bindende molekyler i blodplasma og fremgangsmåde til modifikation af immunogenicitet
|
JP6248029B2
(ja)
|
2011-03-31 |
2017-12-13 |
ジェネンテック, インコーポレイテッド |
ベータ7インテグリンアンタゴニストの投与方法
|
KR20140021589A
(ko)
|
2011-04-07 |
2014-02-20 |
제넨테크, 인크. |
항-fgfr4 항체 및 사용 방법
|
DK2697257T3
(en)
|
2011-04-13 |
2017-01-30 |
Bristol Myers Squibb Co |
FC FUSION PROTEINS INCLUDING UNKNOWN LINKERS OR EVENTS
|
CA2830923A1
(en)
|
2011-04-15 |
2012-10-18 |
Compugen Ltd. |
Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer
|
WO2012143524A2
(en)
|
2011-04-20 |
2012-10-26 |
Genmab A/S |
Bispecific antibodies against her2 and cd3
|
BR112013026306A2
(pt)
|
2011-04-20 |
2017-09-05 |
Roche Glycart Ag |
MÉTODO E CONSTRUTOS PARA A PASSAGEM DE PENDENTE DO pH DA BARREIRA SANGUE-CÉREBRO
|
AU2012245073B2
(en)
|
2011-04-21 |
2016-02-11 |
Garvan Institute Of Medical Research |
Modified variable domain molecules and methods for producing and using them b
|
EA201892619A1
(ru)
|
2011-04-29 |
2019-04-30 |
Роше Гликарт Аг |
Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
|
WO2012155019A1
(en)
|
2011-05-12 |
2012-11-15 |
Genentech, Inc. |
Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature pepides
|
EP3388443A1
(en)
|
2011-05-13 |
2018-10-17 |
Biogen MA Inc. |
Methods of preventing and removing trisulfide bonds
|
WO2012158818A2
(en)
|
2011-05-16 |
2012-11-22 |
Fabion Pharmaceuticals, Inc. |
Multi-specific fab fusion proteins and methods of use
|
EA030462B1
(ru)
|
2011-05-16 |
2018-08-31 |
Дженентек, Инк. |
Агонисты fgfr1 и способы их применения
|
CA2837169C
(en)
|
2011-05-24 |
2021-11-09 |
Zyngenia, Inc. |
Multispecific complexes comprising angiopoietin-2-binding peptide and their uses
|
MX351600B
(es)
|
2011-06-03 |
2017-10-20 |
Xoma Technology Ltd |
Anticuerpo especificos para tgf-beta.
|
DK2718326T3
(da)
|
2011-06-13 |
2020-10-26 |
Csl Ltd |
Antistoffer mod g-csfr og anvendelser deraf
|
CA2837914A1
(en)
|
2011-06-15 |
2012-12-20 |
F. Hoffmann-La Roche Ag |
Anti-human epo receptor antibodies and methods of use
|
CA2836855C
(en)
|
2011-06-30 |
2020-07-14 |
Compugen Ltd. |
Polypeptides and uses thereof for treatment of autoimmune disorders and infection
|
TW201306866A
(zh)
|
2011-06-30 |
2013-02-16 |
Genentech Inc |
抗-c-met抗體調配物
|
BR112013032630B1
(pt)
|
2011-06-30 |
2022-06-14 |
Chugai Seiyaku Kabushiki Kaisha |
Polipeptídeo heterodimerizado compreendendo região fc de igg
|
JP2013040160A
(ja)
|
2011-07-01 |
2013-02-28 |
Genentech Inc |
自己免疫疾患を治療するための抗cd83アゴニスト抗体の使用
|
EP2543680A1
(en)
|
2011-07-07 |
2013-01-09 |
Centre National de la Recherche Scientifique |
Multispecific mutated antibody Fab fragments
|
CN106167526A
(zh)
|
2011-07-15 |
2016-11-30 |
昂考梅德药品有限公司 |
Rspo结合剂和其应用
|
EP2734239A2
(en)
|
2011-07-18 |
2014-05-28 |
Arts Biologics A/S |
Long acting luteinizing hormone (lh) compound
|
SG2014007686A
(en)
|
2011-08-05 |
2014-03-28 |
Regeneron Pharma |
Humanized universal light chain mice
|
CN103890007A
(zh)
|
2011-08-17 |
2014-06-25 |
霍夫曼-拉罗奇有限公司 |
神经调节蛋白抗体及其用途
|
MX2014001736A
(es)
|
2011-08-17 |
2014-03-31 |
Genentech Inc |
Inhibicion de angiogenesis en tumores refractarios.
|
RU2014109038A
(ru)
|
2011-08-23 |
2015-09-27 |
Рош Гликарт Аг |
Антитела к хондроитинсульфат протеогликану меланомы
|
BR112014003598B1
(pt)
|
2011-08-23 |
2022-05-31 |
Roche Glycart Ag |
Molécula de ligação de antígeno biespecífica, composição farmacêutica e uso da molécula de ligação de antígeno biespecífica
|
RU2605390C2
(ru)
|
2011-08-23 |
2016-12-20 |
Рош Гликарт Аг |
Биспецифические антитела, специфичные к антигенам, активирующим т-клетки, и опухолевому антигену, и способы их применения
|
WO2013026837A1
(en)
|
2011-08-23 |
2013-02-28 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
PE20141521A1
(es)
|
2011-08-23 |
2014-10-25 |
Roche Glycart Ag |
Moleculas biespecificas de union a antigeno activadoras de celulas t
|
AU2012300279A1
(en)
|
2011-08-26 |
2014-04-03 |
Merrimack Pharmaceuticals, Inc. |
Tandem Fc bispecific antibodies
|
WO2013033069A1
(en)
|
2011-08-30 |
2013-03-07 |
Theraclone Sciences, Inc. |
Human rhinovirus (hrv) antibodies
|
KR101851425B1
(ko)
|
2011-09-02 |
2018-04-23 |
네스텍 소시에테아노님 |
치료 효능 결정을 위한 신호 경로 단백질의 프로파일링
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
CN103930781A
(zh)
|
2011-09-15 |
2014-07-16 |
霍夫曼-拉罗奇有限公司 |
促进分化的方法
|
GB201116092D0
(en)
|
2011-09-16 |
2011-11-02 |
Bioceros B V |
Antibodies and uses thereof
|
US20130078252A1
(en)
|
2011-09-19 |
2013-03-28 |
Genentech, Inc. |
Combination treatments comprising c-met antagonists and b-raf antagonists
|
ES2707580T3
(es)
|
2011-09-23 |
2019-04-04 |
Oncomed Pharm Inc |
Agentes de unión a VEGF/DLL4 y usos de los mismos
|
EP2758435A1
(en)
|
2011-09-23 |
2014-07-30 |
Roche Glycart AG |
Bispecific anti-egfr/anti igf-1r antibodies
|
KR101982899B1
(ko)
|
2011-09-30 |
2019-05-27 |
테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 |
TL1a에 대한 항체 및 그의 용도
|
US9663573B2
(en)
|
2011-10-05 |
2017-05-30 |
Genentech, Inc. |
Methods of treating liver conditions using Notch2 antagonists
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
CA2850818A1
(en)
*
|
2011-10-11 |
2013-04-18 |
Genentech, Inc. |
Improved assembly of bispecific antibodies
|
CN108373506A
(zh)
|
2011-10-14 |
2018-08-07 |
霍夫曼-拉罗奇有限公司 |
抗HtrA1抗体及使用方法
|
EP2766000A2
(en)
|
2011-10-15 |
2014-08-20 |
F.Hoffmann-La Roche Ag |
Scd1 antagonists for treating cancer
|
WO2013059531A1
(en)
|
2011-10-20 |
2013-04-25 |
Genentech, Inc. |
Anti-gcgr antibodies and uses thereof
|
EP2771028A2
(en)
|
2011-10-24 |
2014-09-03 |
Halozyme, Inc. |
Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
|
HUE044633T2
(hu)
|
2011-10-27 |
2019-11-28 |
Genmab As |
Heterodimer fehérjék elõállítása
|
AU2012328980A1
(en)
|
2011-10-28 |
2014-04-24 |
Genentech, Inc. |
Therapeutic combinations and methods of treating melanoma
|
US9265817B2
(en)
|
2011-10-28 |
2016-02-23 |
Patrys Limited |
PAT-LM1 epitopes and methods for using same
|
RU2681885C2
(ru)
|
2011-10-31 |
2019-03-13 |
Чугаи Сейяку Кабусики Кайся |
Антигенсвязывающая молекула с регулируемой конъюгацией между тяжелой цепью и легкой цепью
|
DK2773438T4
(da)
|
2011-11-02 |
2022-01-03 |
Hoffmann La Roche |
Overladnings- og elueringskromatografi
|
CA2854233C
(en)
|
2011-11-04 |
2020-05-12 |
Zymeworks Inc. |
Stable heterodimeric antibody design with mutations in the fc domain
|
MX2014005411A
(es)
|
2011-11-04 |
2015-02-12 |
Novartis Ag |
Construcciones prolongadas de la vida media de la proteina relacionada con lipoproteina de baja densidad 6 (lrp6).
|
MX2014006087A
(es)
|
2011-11-21 |
2014-08-01 |
Immunogen Inc |
Metodo de tratamiento de tumores que son resistentes a terapias contra el receptor del factor de crecimiento epidermico (egfr) con agentes citotoxicos conjugados con anticuerpos dirigidos contra el receptor del factor de crecimiento epidermico.
|
BR112014012005A2
(pt)
|
2011-11-21 |
2017-12-19 |
Genentech Inc |
composições, métodos, formulação farmacêutica e artigo
|
JP2015505300A
(ja)
|
2011-11-23 |
2015-02-19 |
アムジエン・インコーポレーテツド |
インターフェロンγに対する抗体を使用した治療方法
|
CN104080909A
(zh)
|
2011-11-30 |
2014-10-01 |
中外制药株式会社 |
包含进入细胞内以形成免疫复合体的搬运体(载体)的药物
|
WO2013083497A1
(en)
|
2011-12-06 |
2013-06-13 |
F. Hoffmann-La Roche Ag |
Antibody formulation
|
BR112014015078A2
(pt)
|
2011-12-21 |
2017-06-13 |
Amgen Inc |
polipeptídeos-fc variantes com ligação melhorada ao receptor fc neonatal
|
MX355624B
(es)
|
2011-12-22 |
2018-04-25 |
Hoffmann La Roche |
Combinaciones de elementos de vector de expresion, metodos novedosos de generacion de celulas de produccion y su uso para la produccion recombinante de polipeptidos.
|
MX2014007262A
(es)
*
|
2011-12-22 |
2014-08-01 |
Hoffmann La Roche |
Sistema de exhibicion de anticuerpos de longitud completa para celulas eucarioticas y su uso.
|
SG10201805622QA
(en)
|
2011-12-22 |
2018-08-30 |
Hoffmann La Roche |
Expression Vector Organization, Novel Production Cell Generation Methods And Their Use For The Recombinant Production Of Polypeptides
|
AR089434A1
(es)
|
2011-12-23 |
2014-08-20 |
Genentech Inc |
Procedimiento para preparar formulaciones con alta concentracion de proteinas
|
US20130195851A1
(en)
|
2011-12-23 |
2013-08-01 |
Genentech, Inc. |
Articles of manufacture and methods for co-administration of antibodies
|
WO2013101771A2
(en)
|
2011-12-30 |
2013-07-04 |
Genentech, Inc. |
Compositions and method for treating autoimmune diseases
|
KR20140119114A
(ko)
|
2012-01-18 |
2014-10-08 |
제넨테크, 인크. |
Fgf19 조절제의 사용 방법
|
SG11201404198TA
(en)
|
2012-01-18 |
2014-08-28 |
Genentech Inc |
Anti-lrp5 antibodies and methods of use
|
SG11201404486QA
(en)
|
2012-01-31 |
2014-11-27 |
Genentech Inc |
Anti-ig-e m1' antibodies and methods using same
|
RU2693264C2
(ru)
|
2012-02-03 |
2019-07-01 |
Ф.Хоффман-Ля Рош Аг |
Молекулы биспецифических антител и т-клетки, трансфецированные антигеном, и их применение в медицине
|
EP2812443B1
(en)
|
2012-02-06 |
2019-05-29 |
Inhibrx, Inc. |
Cd47 antibodies and methods of use thereof
|
MX2014009565A
(es)
|
2012-02-10 |
2014-11-10 |
Genentech Inc |
Anticuerpos monocatenarios y otros heteromultimeros.
|
US20130209473A1
(en)
|
2012-02-11 |
2013-08-15 |
Genentech, Inc. |
R-spondin translocations and methods using the same
|
CA2860600C
(en)
|
2012-02-15 |
2022-07-26 |
F. Hoffmann-La Roche Ag |
Fc-receptor based affinity chromatography
|
ES2795419T3
(es)
|
2012-02-24 |
2020-11-23 |
Chugai Pharmaceutical Co Ltd |
Molécula de unión al antígeno que promueve la desaparición del antígeno vía Fc RIIB
|
PE20150090A1
(es)
|
2012-02-24 |
2015-02-16 |
Stem Centrx Inc |
Moduladores y metodos de empleo novedosos referencia cruzada a solicitudes
|
JP6193275B2
(ja)
|
2012-03-02 |
2017-09-06 |
ヴァクシネックス, インコーポレイテッド |
B細胞媒介炎症性疾患を治療するための方法
|
WO2013134414A1
(en)
*
|
2012-03-06 |
2013-09-12 |
Galaxy Biotech, Llc |
Bispecific antibodies with an fgf2 binding domain
|
US10988516B2
(en)
|
2012-03-26 |
2021-04-27 |
Uti Limited Partnership |
Methods and compositions for treating inflammation
|
JP2015514710A
(ja)
|
2012-03-27 |
2015-05-21 |
ジェネンテック, インコーポレイテッド |
Her3阻害剤に関する診断及び治療
|
CA2862516C
(en)
|
2012-03-27 |
2023-02-14 |
Ngm Biopharmaceuticals, Inc. |
Compositions and methods of use for treating metabolic disorders
|
HUE037613T2
(hu)
|
2012-03-29 |
2018-09-28 |
Novimmune Sa |
Anti-TLR4 antitestek és azok felhasználása
|
CA2868883C
(en)
|
2012-03-30 |
2022-10-04 |
Sorrento Therapeutics Inc. |
Fully human antibodies that bind to vegfr2
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
BR112014024903A2
(pt)
|
2012-04-05 |
2017-07-11 |
Hoffmann La Roche |
anticorpos biespecíficos contra tweak humanao e il17 humana e seus usos
|
WO2013180834A2
(en)
|
2012-04-06 |
2013-12-05 |
Omeros Corporation |
Compositions and methods of inhibting masp-1 and/or masp-3 for the treatment of paroxysmal nocturnal hemoglobinuria
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
JP6509724B2
(ja)
|
2012-04-20 |
2019-05-08 |
アプティーボ リサーチ アンド デベロップメント エルエルシー |
Cd3結合ポリペプチド
|
SI2838918T1
(sl)
|
2012-04-20 |
2019-11-29 |
Merus Nv |
Postopki in sredstva za proizvodnjo heterodimernih IG-podobnih molekul
|
US9212227B2
(en)
|
2012-04-30 |
2015-12-15 |
Janssen Biotech, Inc. |
ST2L antibody antagonists for the treatment of ST2L-mediated inflammatory pulmonary conditions
|
EP2844300B1
(en)
|
2012-05-01 |
2018-10-17 |
Genentech, Inc. |
Anti-pmel17 antibodies and immunoconjugates
|
WO2013164325A1
(en)
*
|
2012-05-02 |
2013-11-07 |
F. Hoffmann-La Roche Ag |
Multispecific antigen binding proteins
|
CN104583239B
(zh)
|
2012-05-10 |
2018-09-18 |
生物蛋白有限公司 |
多特异单克隆抗体
|
WO2013170191A1
(en)
|
2012-05-11 |
2013-11-14 |
Genentech, Inc. |
Methods of using antagonists of nad biosynthesis from nicotinamide
|
KR102293061B1
(ko)
|
2012-05-21 |
2021-08-23 |
제넨테크, 인크. |
혈액-뇌 장벽 수송의 안전성을 개선하는 방법
|
RU2625771C2
(ru)
|
2012-05-23 |
2017-07-18 |
Дженентек, Инк. |
Способ отбора терапевтических средств
|
CA2869529A1
(en)
|
2012-05-24 |
2013-11-28 |
Raffaella CASTOLDI |
Multispecific antibodies
|
JPWO2013180200A1
(ja)
|
2012-05-30 |
2016-01-21 |
中外製薬株式会社 |
標的組織特異的抗原結合分子
|
CA2872030A1
(en)
|
2012-05-31 |
2013-12-05 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind pd-l1
|
JP2015520192A
(ja)
|
2012-06-06 |
2015-07-16 |
オンコメッド ファーマシューティカルズ インコーポレイテッド |
Hippo経路を調節する結合剤およびその使用
|
EP4310191A3
(en)
|
2012-06-14 |
2024-05-15 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule containing modified fc region
|
US9266961B2
(en)
|
2012-06-15 |
2016-02-23 |
Genentech, Inc. |
Anti-PCSK9 antibodies, formulations, dosing, and methods of use
|
ES2864857T3
(es)
|
2012-06-18 |
2021-10-14 |
Omeros Corp |
Composiciones y métodos para la inhibición de MASP-1 y/o MASP-2 y/o MASP-3 para el tratamiento de diversas enfermedades y trastornos
|
JP6429771B2
(ja)
|
2012-06-21 |
2018-11-28 |
ソレント・セラピューティクス・インコーポレイテッドSorrento Therapeutics, Inc. |
c−Metに結合する抗原結合タンパク質
|
US9890215B2
(en)
|
2012-06-22 |
2018-02-13 |
King's College London |
Vista modulators for diagnosis and treatment of cancer
|
CA2877814A1
(en)
|
2012-06-22 |
2013-12-27 |
Dingqiu HUANG |
Antigen binding proteins that bind ccr2
|
WO2014004586A1
(en)
|
2012-06-25 |
2014-01-03 |
Zymeworks Inc. |
Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
|
MX2014014804A
(es)
|
2012-06-27 |
2015-02-12 |
Hoffmann La Roche |
Metodo para la elaboracion de conjugados de la region fc de anticuerpos que comprenden por lo menos una entidad de union que se une especificamente a un objetivo y usos del mismo.
|
MX354862B
(es)
|
2012-06-27 |
2018-03-23 |
Hoffmann La Roche |
Método para la producción de entidades dirigidas altamente selectivas hechas a la medida y biespecíficas que contienen dos entidades de unión diferentes.
|
SI2869848T1
(sl)
|
2012-07-04 |
2017-01-31 |
F. Hoffmann-La Roche Ag |
Kovalentno vezani konjugati antigen-protitelo
|
EP2870180B1
(en)
|
2012-07-04 |
2024-08-28 |
F. Hoffmann-La Roche AG |
Anti-biotin antibodies and methods of use
|
BR112014030843A2
(pt)
|
2012-07-04 |
2019-10-15 |
Hoffmann La Roche |
anticorpo anti-teofilina, formulação farmacêutica e uso do anticorpo
|
CN110042114B
(zh)
|
2012-07-05 |
2024-09-10 |
弗·哈夫曼-拉罗切有限公司 |
表达和分泌系统
|
EP2869845B1
(en)
|
2012-07-06 |
2019-08-28 |
Genmab B.V. |
Dimeric protein with triple mutations
|
BR112015000437A2
(pt)
|
2012-07-09 |
2017-06-27 |
Genentech Inc |
imunoconjugados, formulação farmacêutica, métodos de tratamento e de inbir a proliferação de uma célula
|
TW201406785A
(zh)
|
2012-07-09 |
2014-02-16 |
Genentech Inc |
抗cd22抗體及免疫結合物
|
WO2014011520A1
(en)
|
2012-07-09 |
2014-01-16 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd22 antibodies
|
TR201802376T4
(tr)
|
2012-07-09 |
2018-03-21 |
Genentech Inc |
Anti-CD79b antikorları içeren immünokonjugatlar.
|
EP2684896A1
(en)
|
2012-07-09 |
2014-01-15 |
International-Drug-Development-Biotech |
Anti-DR5 family antibodies, bispecific or multivalent anti-DR5 family antibodies and methods of use thereof
|
AR092027A1
(es)
|
2012-07-13 |
2015-03-18 |
Roche Glycart Ag |
Anticuerpos biespecificos anti-vegf/anti-ang-2 y su utilizacion en el tratamiento de enfermedades vasculares oculares
|
EP3730512A1
(en)
|
2012-07-13 |
2020-10-28 |
The Trustees of the University of Pennsylvania |
Enhancing activity of car t cells by co-introducing a bispecific antibody
|
CN104768571B
(zh)
|
2012-07-13 |
2018-11-09 |
酵活有限公司 |
多价异多聚体支架设计和构建体
|
EP2875046B1
(en)
|
2012-07-19 |
2020-02-26 |
Amgen Inc. |
Human btnl3 proteins, nucleic acids, and antibodies and uses thereof
|
ES2848732T3
(es)
|
2012-08-07 |
2021-08-11 |
Roche Glycart Ag |
Inmunoterapia mejorada
|
PE20150645A1
(es)
|
2012-08-08 |
2015-05-11 |
Roche Glycart Ag |
Proteinas de fusion de interleuquina 10 y usos de las mismas
|
CN104704001B
(zh)
|
2012-08-09 |
2019-02-12 |
罗切格利卡特公司 |
Asgpr抗体及其用途
|
US20140044675A1
(en)
|
2012-08-10 |
2014-02-13 |
Roche Glycart Ag |
Interleukin-2 fusion proteins and uses thereof
|
FR2994390B1
(fr)
|
2012-08-10 |
2014-08-15 |
Adocia |
Procede d'abaissement de la viscosite de solutions de proteines a concentration elevee
|
AU2013306098A1
(en)
|
2012-08-18 |
2015-02-12 |
Academia Sinica |
Cell-permeable probes for identification and imaging of sialidases
|
US9758591B2
(en)
|
2012-08-24 |
2017-09-12 |
The Regents Of The University Of California |
Antibodies and vaccines for use in treating ROR1 cancers and inhibiting metastasis
|
US10919953B2
(en)
|
2012-08-24 |
2021-02-16 |
Chugai Seiyaku Kabushiki Kaisha |
FcgammaRIIB-specific Fc region variant
|
KR20200079565A
(ko)
|
2012-08-31 |
2020-07-03 |
이뮤노젠 아이엔씨 |
엽산 수용체 1의 검출을 위한 진단성 검정 및 키트
|
CN109793893B
(zh)
|
2012-09-07 |
2023-05-26 |
达特茅斯大学理事会 |
用于诊断和治疗癌症的vista调节剂
|
KR101963231B1
(ko)
|
2012-09-11 |
2019-03-28 |
삼성전자주식회사 |
이중특이 항체의 제작을 위한 단백질 복합체 및 이를 이용한 이중특이 항체 제조 방법
|
US10393733B2
(en)
|
2012-09-19 |
2019-08-27 |
Dana-Farber Cancer Institute, Inc. |
Dynamic BH3 profiling
|
AU2013318047A1
(en)
|
2012-09-19 |
2015-03-12 |
Genentech, Inc. |
Methods and compositions for preventing norleucine misincorporation into proteins
|
IN2015MN00139A
(fi)
|
2012-09-25 |
2015-10-16 |
Glenmark Pharmaceuticals Sa |
|
SG10201705787VA
(en)
|
2012-09-27 |
2017-08-30 |
Merus Nv |
BISPECIFIC IgG ANTIBODIES AS T CELL ENGAGERS
|
WO2014055784A1
(en)
|
2012-10-03 |
2014-04-10 |
Zymeworks Inc. |
Methods of quantitating heavy and light chain polypeptide pairs
|
BR112015007528A2
(pt)
|
2012-10-05 |
2018-09-04 |
Genentech Inc |
método para prever a resposta, para prever a responsividade, para identificar e para tratar um paciente que tem uma disfunção inflamatória gastrointestinal.
|
US9598489B2
(en)
|
2012-10-05 |
2017-03-21 |
The Trustees Of The Univeristy Of Pennsylvania |
Human alpha-folate receptor chimeric antigen receptor
|
RU2015117393A
(ru)
|
2012-10-08 |
2016-12-10 |
Роше Гликарт Аг |
Лишенные fc антитела, содержащие два Fab-фрагмента, и способы их применения
|
US9603948B2
(en)
|
2012-10-11 |
2017-03-28 |
Uti Limited Partnership |
Methods and compositions for treating multiple sclerosis and related disorders
|
WO2014062856A1
(en)
|
2012-10-16 |
2014-04-24 |
Halozyme, Inc. |
Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods
|
US9309318B2
(en)
|
2012-10-17 |
2016-04-12 |
Amgen, Inc. |
Compositions relating to anti-IL-21 receptor antibodies
|
EP2914961A4
(en)
|
2012-10-31 |
2016-04-20 |
Oncomed Pharm Inc |
METHODS AND MONITORING A TREATMENT BY AN ANTAGONIST OF DLL4
|
WO2014071358A2
(en)
|
2012-11-05 |
2014-05-08 |
Foundation Medicine, Inc. |
Novel ntrk1 fusion molecules and uses thereof
|
MX2015005831A
(es)
|
2012-11-08 |
2015-09-24 |
Eleven Biotherapeutics Inc |
Antagonistas de il-6 y usos de los mismos.
|
EP2917243B1
(en)
|
2012-11-08 |
2018-03-14 |
F.Hoffmann-La Roche Ag |
Her3 antigen binding proteins binding to the beta-hairpin of her3
|
SG11201503734UA
(en)
|
2012-11-13 |
2015-06-29 |
Genentech Inc |
Anti-hemagglutinin antibodies and methods of use
|
EP2920586A4
(en)
|
2012-11-15 |
2017-01-04 |
F. Hoffmann-La Roche SA |
IONIC STRENGTH-MEDIATED pH GRADIENT ION EXCHANGE CHROMATOGRAPHY
|
EP2927321B1
(en)
|
2012-11-27 |
2021-02-17 |
Ajou University Industry-Academic Cooperation Foundation |
Ch3 domain variant pair inducing formation of heterodimer of heavy chain constant region of antibody at high efficiency, method for preparing same, and use thereof
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
KR102264570B1
(ko)
|
2012-11-28 |
2021-06-14 |
자임워크스 인코포레이티드 |
가공된 면역글로불린 중쇄-경쇄 쌍 및 이들의 용도
|
ES2784631T3
(es)
|
2012-12-03 |
2020-09-29 |
Novimmune Sa |
Anticuerpos anti-CD47 y métodos de uso de los mismos
|
NZ709059A
(en)
|
2012-12-04 |
2016-11-25 |
Oncomed Pharm Inc |
Immunotherapy with binding agents
|
EP3686218A1
(en)
|
2012-12-10 |
2020-07-29 |
Biogen MA Inc. |
Anti-blood dendritic cell antigen 2 antibodies and uses thereof
|
EP2935589A1
(en)
|
2012-12-18 |
2015-10-28 |
Novartis AG |
Compositions and methods that utilize a peptide tag that binds to hyaluronan
|
EP2940135B9
(en)
|
2012-12-27 |
2021-09-08 |
Chugai Seiyaku Kabushiki Kaisha |
Heterodimerized polypeptide
|
EP3620473A1
(en)
|
2013-01-14 |
2020-03-11 |
Xencor, Inc. |
Novel heterodimeric proteins
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
EP2945969A1
(en)
|
2013-01-15 |
2015-11-25 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
EP3939614A1
(en)
|
2013-01-18 |
2022-01-19 |
Foundation Medicine, Inc. |
Methods of treating cholangiocarcinoma
|
WO2014116749A1
(en)
|
2013-01-23 |
2014-07-31 |
Genentech, Inc. |
Anti-hcv antibodies and methods of using thereof
|
US9161966B2
(en)
|
2013-01-30 |
2015-10-20 |
Ngm Biopharmaceuticals, Inc. |
GDF15 mutein polypeptides
|
DK2951208T3
(da)
|
2013-02-01 |
2020-01-13 |
Kira Biotech Pty Ltd |
Anti-cd83 antistoffer og anvendelse deraf
|
EP2762497A1
(en)
|
2013-02-05 |
2014-08-06 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
WO2014122144A1
(en)
|
2013-02-05 |
2014-08-14 |
Engmab Ag |
BISPECIFIC ANTIBODIES AGAINST CD3ε AND BCMA
|
EP2762496A1
(en)
|
2013-02-05 |
2014-08-06 |
EngMab AG |
Method for the selection of antibodies against BCMA
|
SG11201506132PA
(en)
|
2013-02-06 |
2015-09-29 |
Inhibrx Llc |
Non-platelet depleting and non-red blood cell depleting cd47 antibodies and methods of use thereof
|
JP6545105B2
(ja)
|
2013-02-07 |
2019-07-17 |
シーエスエル、リミテッド |
Il−11r結合タンパク質及びその使用
|
CA2900764A1
(en)
|
2013-02-08 |
2014-08-14 |
Stemcentrx, Inc. |
Novel multispecific constructs
|
WO2014126871A1
(en)
|
2013-02-12 |
2014-08-21 |
Bristol-Myers Squibb Company |
Tangential flow filtration based protein refolding methods
|
ES2645634T3
(es)
|
2013-02-12 |
2017-12-07 |
Bristol-Myers Squibb Company |
Métodos de replegado de proteínas a elevado pH
|
US9573988B2
(en)
|
2013-02-20 |
2017-02-21 |
Novartis Ag |
Effective targeting of primary human leukemia using anti-CD123 chimeric antigen receptor engineered T cells
|
PL2958943T3
(pl)
|
2013-02-20 |
2020-04-30 |
The Trustees Of The University Of Pennsylvania |
Leczenie nowotworu złośliwego za pomocą humanizowanego chimerycznego receptora antygenowego anty-egfrviii
|
DK2958944T3
(da)
|
2013-02-22 |
2019-06-24 |
Abbvie Stemcentrx Llc |
Anti-dll3-antistof-pbd-konjugater og anvendelser deraf
|
KR20150118159A
(ko)
|
2013-02-22 |
2015-10-21 |
에프. 호프만-라 로슈 아게 |
암의 치료 방법 및 약물 내성의 예방 방법
|
WO2014130923A2
(en)
|
2013-02-25 |
2014-08-28 |
Genentech, Inc. |
Methods and compositions for detecting and treating drug resistant akt mutant
|
NZ708182A
(en)
|
2013-02-26 |
2019-08-30 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
WO2014131711A1
(en)
|
2013-02-26 |
2014-09-04 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
JP2016512489A
(ja)
|
2013-02-26 |
2016-04-28 |
ロシュ グリクアート アーゲー |
抗mcsp抗体
|
CN105143270B
(zh)
|
2013-02-26 |
2019-11-12 |
罗切格利卡特公司 |
双特异性t细胞活化抗原结合分子
|
US9487587B2
(en)
|
2013-03-05 |
2016-11-08 |
Macrogenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof
|
KR20150123250A
(ko)
|
2013-03-06 |
2015-11-03 |
제넨테크, 인크. |
암 약물 내성의 치료 및 예방 방법
|
JP2016510755A
(ja)
|
2013-03-06 |
2016-04-11 |
メリマック ファーマシューティカルズ インコーポレーティッド |
抗C−METタンデムFc二重特異性抗体
|
CA2902442A1
(en)
|
2013-03-08 |
2014-09-12 |
Vaccinex, Inc. |
Anti-cxcl13 antibodies and associated epitope sequences
|
JOP20140087B1
(ar)
|
2013-03-13 |
2021-08-17 |
Amgen Inc |
بروتينات مخصصة ل baff و b7rp1 وإستخداماتها
|
US9458246B2
(en)
|
2013-03-13 |
2016-10-04 |
Amgen Inc. |
Proteins specific for BAFF and B7RP1
|
SG10201913932VA
(en)
|
2013-03-13 |
2020-03-30 |
Genentech Inc |
Antibody formulations
|
WO2014160497A1
(en)
|
2013-03-13 |
2014-10-02 |
Genentech, Inc. |
Formulations with reduced oxidation
|
PT2968466T
(pt)
|
2013-03-13 |
2018-10-22 |
Hoffmann La Roche |
Formulações de oxidação reduzida
|
US20140314778A1
(en)
|
2013-03-13 |
2014-10-23 |
Genentech, Inc. |
Formulations with reduced oxidation
|
US10653779B2
(en)
|
2013-03-13 |
2020-05-19 |
Genentech, Inc. |
Formulations with reduced oxidation
|
WO2014153030A2
(en)
|
2013-03-14 |
2014-09-25 |
Genentech, Inc. |
Methods of treating cancer and preventing cancer drug resistance
|
JP6676521B2
(ja)
|
2013-03-14 |
2020-04-08 |
マクロジェニクス,インコーポレーテッド |
二重特異性分子、薬学的組成物及びそれらの使用
|
BR112015022019A2
(pt)
|
2013-03-14 |
2017-08-29 |
Genentech Inc |
Anticorpos isolados, ácido nucleico, célula hospedeira, método de produção de anticorpos, imunoconjugado, formulação farmacêutica, métodos de tratamento de indivíduos, de inibição da proliferação de células, de detecção de b7-h4 humano e de detecção de câncer
|
US20140271634A1
(en)
|
2013-03-14 |
2014-09-18 |
The Regents Of The University Of California |
Combinations of a mek inhibitor compound with an her3/egfr inhibitor compound and methods of use
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
US9168300B2
(en)
|
2013-03-14 |
2015-10-27 |
Oncomed Pharmaceuticals, Inc. |
MET-binding agents and uses thereof
|
ES2798307T3
(es)
|
2013-03-15 |
2020-12-10 |
Hoffmann La Roche |
Composiciones de cultivo de células con antioxidantes y procedimientos para la producción de polipéptidos
|
JP6594855B2
(ja)
|
2013-03-15 |
2019-10-23 |
ゼンコア インコーポレイテッド |
ヘテロ二量体タンパク質
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
CA2903576C
(en)
|
2013-03-15 |
2021-06-08 |
Nai-Kong V. Cheung |
High affinity anti-gd2 antibodies
|
US20140283157A1
(en)
|
2013-03-15 |
2014-09-18 |
Diadexus, Inc. |
Lipoprotein-associated phospholipase a2 antibody compositions and methods of use
|
WO2014151834A2
(en)
|
2013-03-15 |
2014-09-25 |
Amgen Inc. |
Methods and compositions relating to anti-ccr7 antigen binding proteins
|
JP6463331B2
(ja)
|
2013-03-15 |
2019-01-30 |
イントリンシック ライフサイエンシズ リミテッド ライアビリティ カンパニー |
抗ヘプシジン抗体およびその使用
|
SG11201505926VA
(en)
|
2013-03-15 |
2015-09-29 |
Biogen Ma Inc |
Factor ix polypeptide formulations
|
WO2014143739A2
(en)
|
2013-03-15 |
2014-09-18 |
Biogen Idec Ma Inc. |
Anti-alpha v beta 6 antibodies and uses thereof
|
BR112015023752B1
(pt)
|
2013-03-15 |
2023-11-14 |
Zyngenia, Inc. |
Domínio de reconhecimento modular (mrd), complexo compreendendo mrd e cetuximabe, usos do complexo para inibir a angiogênese e tratar câncer e composição farmacêutica compreendendo o dito complexo
|
SG10201701380TA
(en)
|
2013-03-15 |
2017-04-27 |
Genentech Inc |
Biomarkers and methods of treating pd-1 and pd-l1 related conditions
|
SG11201507427QA
(en)
|
2013-03-15 |
2015-10-29 |
Genentech Inc |
Compositions and methods for diagnosis and treatment of hepatic cancers
|
JP6466904B2
(ja)
|
2013-03-15 |
2019-02-06 |
ヤンセン バイオテツク,インコーポレーテツド |
インターフェロンアルファ及びオメガ抗体アンタゴニスト
|
ES2676023T3
(es)
|
2013-03-15 |
2018-07-16 |
F. Hoffmann-La Roche Ag |
Polipéptidos de IL-22 y proteínas de fusión de IL-22 Fc y métodos de uso
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
WO2014144466A1
(en)
|
2013-03-15 |
2014-09-18 |
Biogen Idec Ma Inc. |
Anti-alpha v beta 6 antibodies and uses thereof
|
AU2014236986A1
(en)
|
2013-03-15 |
2015-09-03 |
Biogen Ma Inc. |
Treatment and prevention of acute kidney injury using anti-alpha v beta 5 antibodies
|
AU2014236769B2
(en)
|
2013-03-15 |
2018-09-27 |
Amgen Inc. |
Heterodimeric bispecific antibodies
|
CA2902910A1
(en)
|
2013-03-15 |
2014-09-25 |
Ac Immune S.A. |
Anti-tau antibodies and methods of use
|
BR112015021521A2
(pt)
|
2013-03-15 |
2017-10-10 |
Genentech Inc |
anticorpos anti-crth2 e métodos para seu uso
|
WO2014145252A2
(en)
|
2013-03-15 |
2014-09-18 |
Milone Michael C |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
CN105339001A
(zh)
|
2013-03-15 |
2016-02-17 |
基因泰克公司 |
治疗癌症和预防癌症耐药性的方法
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
AR095348A1
(es)
|
2013-03-15 |
2015-10-07 |
Genentech Inc |
Medios de cultivo celular y métodos de producción de anticuerpos
|
US20140302037A1
(en)
|
2013-03-15 |
2014-10-09 |
Amgen Inc. |
BISPECIFIC-Fc MOLECULES
|
AU2014232416B2
(en)
|
2013-03-15 |
2017-09-28 |
Xencor, Inc. |
Modulation of T Cells with Bispecific Antibodies and FC Fusions
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
MX2015013288A
(es)
|
2013-03-18 |
2016-04-07 |
Biocerox Prod Bv |
Anticuerpos anti-cd134 (ox40) humanizados y usos de los mismos.
|
WO2014160753A1
(en)
|
2013-03-27 |
2014-10-02 |
Genentech, Inc. |
Use of biomarkers for assessing treatment of gastrointestinal inflammatory disorders with beta7 integrin antagonists
|
CN113621057A
(zh)
|
2013-04-02 |
2021-11-09 |
中外制药株式会社 |
Fc区变体
|
UA118028C2
(uk)
|
2013-04-03 |
2018-11-12 |
Рош Глікарт Аг |
Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування
|
WO2014169076A1
(en)
|
2013-04-09 |
2014-10-16 |
Annexon,,Inc. |
Methods of treatment for neuromyelitis optica
|
MX2015014568A
(es)
|
2013-04-17 |
2016-12-02 |
Genzyme Corp |
Composiciones y metodos para tratar y prevenir la degeneracion macular.
|
UA118029C2
(uk)
|
2013-04-29 |
2018-11-12 |
Ф. Хоффманн-Ля Рош Аг |
Модифіковане антитіло, що зв'язується з людським fcrn, й способи його застосування
|
EP2992011B1
(en)
|
2013-04-29 |
2017-12-13 |
F. Hoffmann-La Roche AG |
Fcrn-binding abolished anti-igf-1r antibodies and their use in the treatment of vascular eye diseases
|
EP2992010B1
(en)
*
|
2013-04-29 |
2021-03-24 |
F.Hoffmann-La Roche Ag |
Fc-receptor binding modified asymmetric antibodies and methods of use
|
CA2910945A1
(en)
|
2013-05-08 |
2014-11-13 |
Zymeworks Inc. |
Bispecific her2 and her3 antigen binding constructs
|
EP2997373A1
(en)
|
2013-05-17 |
2016-03-23 |
MedImmune, LLC |
Receptors for b7-h4
|
PL3594240T3
(pl)
|
2013-05-20 |
2024-04-02 |
F. Hoffmann-La Roche Ag |
Przeciwciała przeciwko receptorowi transferyny i sposoby ich zastosowania
|
EA201591993A1
(ru)
|
2013-05-23 |
2016-05-31 |
Шир Хьюман Дженетик Терапис, Инк. |
Лечение склеродермии с применением комбинированной терапии антителами анти-ccl2 и анти-loxl2
|
CN105579852B
(zh)
|
2013-05-24 |
2017-12-01 |
雀巢产品技术援助有限公司 |
用于诊断肠易激惹综合征的途径特异性标志物
|
AU2014273817B2
(en)
|
2013-05-31 |
2019-03-14 |
Zymeworks Bc Inc. |
Heteromultimers with reduced or silenced effector function
|
JP6563906B2
(ja)
|
2013-05-31 |
2019-08-21 |
ソレント・セラピューティクス・インコーポレイテッドSorrento Therapeutics, Inc. |
Pd−1に結合する抗原結合蛋白質
|
US10086054B2
(en)
|
2013-06-26 |
2018-10-02 |
Academia Sinica |
RM2 antigens and use thereof
|
WO2014210564A1
(en)
|
2013-06-27 |
2014-12-31 |
Academia Sinica |
Glycan conjugates and use thereof
|
MY175896A
(en)
|
2013-07-09 |
2020-07-14 |
Annexon Inc |
Anti-complement factor c1q antibodies and uses thereof
|
WO2015006554A1
(en)
|
2013-07-10 |
2015-01-15 |
The Regents Of The University Of Michigan |
Therapeutic antibodies and uses thereof
|
EP3019516B1
(en)
|
2013-07-12 |
2018-11-14 |
H. Hoffnabb-La Roche Ag |
Elucidation of ion exchange chromatography input optimization
|
KR20220042248A
(ko)
|
2013-07-16 |
2022-04-04 |
제넨테크, 인크. |
Pd-1 축 결합 길항제 및 tigit 억제제를 사용한 암을 치료하는 방법
|
MX2016001854A
(es)
|
2013-08-12 |
2016-09-06 |
Genentech Inc |
Composiciones y metodo para tratar condiciones asociadas con el complemento.
|
EP3033356B1
(en)
|
2013-08-14 |
2020-01-15 |
Sachdev Sidhu |
Antibodies against frizzled proteins and methods of use thereof
|
AU2014312215B2
(en)
|
2013-08-28 |
2020-02-27 |
Abbvie Stemcentrx Llc |
Site-specific antibody conjugation methods and compositions
|
AU2014312310A1
(en)
|
2013-08-28 |
2016-04-07 |
Abbvie Stemcentrx Llc |
Novel SEZ6 modulators and methods of use
|
EP3041865A2
(en)
|
2013-09-03 |
2016-07-13 |
NovImmune S.A. |
Readily isolated bispecific binding molecules with native format having mutated constant regions
|
DK3041862T3
(da)
*
|
2013-09-05 |
2020-07-27 |
Igm Biosciences Inc |
Modificerede bispecifikke, penta- og hexavalente ig-m-antistoffer med konstant kæde
|
US20150093800A1
(en)
|
2013-09-05 |
2015-04-02 |
Genentech, Inc. |
Method for chromatography reuse
|
JP6486368B2
(ja)
|
2013-09-06 |
2019-03-20 |
アカデミア シニカAcademia Sinica |
改変されたグリコシル基を含む糖脂質を用いたヒトiNKT細胞の活性化
|
AR097685A1
(es)
|
2013-09-17 |
2016-04-06 |
Genentech Inc |
Métodos de uso de anticuerpos anti-lgr5
|
EP3047276B1
(en)
|
2013-09-19 |
2023-06-14 |
Dana-Farber Cancer Institute, Inc. |
Methods of bh3 profiling
|
US20160257748A1
(en)
|
2013-09-25 |
2016-09-08 |
Amgen Inc. |
V-c-fc-v-c antibody
|
EP3050896B1
(en)
|
2013-09-27 |
2021-07-07 |
Chugai Seiyaku Kabushiki Kaisha |
Method for producing polypeptide heteromultimer
|
CA2925310C
(en)
|
2013-09-27 |
2022-12-06 |
Genentech, Inc. |
Anti-pdl1 antibody formulations
|
BR112016006502A2
(pt)
|
2013-09-30 |
2017-09-19 |
Chugai Pharmaceutical Co Ltd |
Método para a produção de molécula de ligação de antígeno usando-se fago auxiliar modificado
|
WO2015050959A1
(en)
|
2013-10-01 |
2015-04-09 |
Yale University |
Anti-kit antibodies and methods of use thereof
|
EP3055329B1
(en)
|
2013-10-11 |
2018-06-13 |
F. Hoffmann-La Roche AG |
Multispecific domain exchanged common variable light chain antibodies
|
CA2926084A1
(en)
|
2013-10-11 |
2015-04-16 |
Genentech, Inc. |
Nsp4 inhibitors and methods of use
|
WO2015057939A1
(en)
|
2013-10-18 |
2015-04-23 |
Biogen Idec Ma Inc. |
Anti-s1p4 antibodies and uses thereof
|
CN105744954B
(zh)
|
2013-10-18 |
2021-03-05 |
豪夫迈·罗氏有限公司 |
抗rspo2和/或抗rspo3抗体及其用途
|
KR20160068802A
(ko)
|
2013-10-23 |
2016-06-15 |
제넨테크, 인크. |
호산구성 장애를 진단 및 치료하는 방법
|
JP2016538275A
(ja)
|
2013-11-04 |
2016-12-08 |
グレンマーク ファーマシューティカルズ, エセ.アー. |
T細胞再標的化ヘテロ二量体免疫グロブリン(hetero−dimeric immunoglobulin)の製造
|
EP3065771B1
(en)
|
2013-11-04 |
2019-03-20 |
UTI Limited Partnership |
Methods and compositions for sustained immunotherapy
|
PE20160856A1
(es)
|
2013-11-06 |
2016-09-03 |
Janssen Biotech Inc |
Anticuerpos anti-ccl17
|
CN113307873A
(zh)
|
2013-11-11 |
2021-08-27 |
中外制药株式会社 |
含有改变了抗体可变区的抗原结合分子
|
CA2930307A1
(en)
|
2013-11-13 |
2015-05-21 |
Zymeworks Inc. |
Monovalent antigen binding constructs targeting egfr and/or her2 and uses thereof
|
LT3071597T
(lt)
|
2013-11-21 |
2020-10-12 |
F. Hoffmann-La Roche Ag |
Antikūnai prieš alfa-sunukleiną ir jų naudojimo būdai
|
AU2014357292B2
(en)
|
2013-11-27 |
2020-06-25 |
Zymeworks Bc Inc. |
Bispecific antigen-binding constructs targeting HER2
|
AU2014358191B2
(en)
|
2013-12-04 |
2020-12-24 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecules, the antigen-binding activity of which varies according to the concentration of compounds, and libraries of said molecules
|
CN110590950A
(zh)
|
2013-12-13 |
2019-12-20 |
基因泰克公司 |
抗cd33抗体和免疫缀合物
|
RU2016128726A
(ru)
|
2013-12-17 |
2018-01-23 |
Дженентек, Инк. |
Способы лечения злокачественных опухолей с использованием антагонистов связывания по оси pd-1 и антитела против cd20
|
WO2015095392A1
(en)
|
2013-12-17 |
2015-06-25 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
EP3083687A2
(en)
|
2013-12-17 |
2016-10-26 |
F. Hoffmann-La Roche AG |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
EP3083686B2
(en)
|
2013-12-17 |
2023-03-22 |
F. Hoffmann-La Roche AG |
Methods of treating cancers using pd-1 axis binding antagonists and taxanes
|
EP3082860B1
(en)
|
2013-12-18 |
2020-11-25 |
CSL Limited |
Method of treating wounds
|
CN116478927A
(zh)
|
2013-12-19 |
2023-07-25 |
诺华股份有限公司 |
人间皮素嵌合抗原受体及其用途
|
JP6608827B2
(ja)
|
2013-12-20 |
2019-11-20 |
エフ.ホフマン−ラ ロシュ アーゲー |
ヒト化抗タウ(pS422)抗体及び使用方法
|
WO2015090229A1
(en)
|
2013-12-20 |
2015-06-25 |
Novartis Ag |
Regulatable chimeric antigen receptor
|
TWI670283B
(zh)
|
2013-12-23 |
2019-09-01 |
美商建南德克公司 |
抗體及使用方法
|
EP4043493A1
(en)
|
2013-12-24 |
2022-08-17 |
Janssen Pharmaceutica NV |
Anti-vista antibodies and fragments
|
LT3087095T
(lt)
|
2013-12-24 |
2019-09-10 |
Argenx Bvba |
Fcrn-antagonistai ir naudojimo būdai
|
US11014987B2
(en)
|
2013-12-24 |
2021-05-25 |
Janssen Pharmaceutics Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
PL3089996T3
(pl)
|
2014-01-03 |
2021-12-13 |
F. Hoffmann-La Roche Ag |
Dwuswoiste przeciwciała przeciw haptenowi/przeciw receptorowi występującemu w barierze krew-mózg, ich kompleksy i ich zastosowanie jako przenośniki wahadłowe występujące w barierze krew-mózg
|
CN105873615B
(zh)
|
2014-01-03 |
2020-12-25 |
豪夫迈·罗氏有限公司 |
共价连接的helicar-抗helicar抗体缀合物及其用途
|
WO2015103026A2
(en)
|
2014-01-03 |
2015-07-09 |
The Regents Of The University Of Michigan |
Treatment of neurological disorders
|
RU2682754C2
(ru)
|
2014-01-03 |
2019-03-21 |
Ф. Хоффманн-Ля Рош Аг |
Конъюгаты полипептидного токсина и антитела, соединенных ковалентной связью
|
PL3092251T3
(pl)
|
2014-01-06 |
2021-08-02 |
F. Hoffmann-La Roche Ag |
Jednowartościowe moduły transportera wahadłowego przez barierę krew-mózg
|
EP3093295B1
(en)
|
2014-01-08 |
2020-05-27 |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
Il-15 heterogeneous dimer protein and uses thereof
|
EP3094648A1
(en)
|
2014-01-15 |
2016-11-23 |
F. Hoffmann-La Roche AG |
Fc-region variants with improved protein a-binding
|
WO2015107026A1
(en)
|
2014-01-15 |
2015-07-23 |
F. Hoffmann-La Roche Ag |
Fc-region variants with modified fcrn- and maintained protein a-binding properties
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
US9982041B2
(en)
|
2014-01-16 |
2018-05-29 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
US11028143B2
(en)
|
2014-01-21 |
2021-06-08 |
Novartis Ag |
Enhanced antigen presenting ability of RNA CAR T cells by co-introduction of costimulatory molecules
|
JP2017505305A
(ja)
|
2014-01-24 |
2017-02-16 |
ジェネンテック, インコーポレイテッド |
抗steap1抗体及びイムノコンジュゲートを使用する方法
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
MX2016010030A
(es)
|
2014-02-02 |
2017-04-27 |
Medimmune Ltd |
Proteina quimerica compuesta del dominio antagonista de factor de crecimiento nervioso secretado (ngf) y un dominio antagonista de factor alfa de necrosis tumoral (tnfa).
|
ES2694857T3
(es)
|
2014-02-04 |
2018-12-27 |
Genentech, Inc. |
Smoothened mutante y métodos de uso de la misma
|
CR20160333A
(es)
|
2014-02-06 |
2016-09-05 |
F Hoffman-La Roche Ag |
Proteinas de fusión de interleucina-2 y usos de las mismas
|
MX2016010215A
(es)
|
2014-02-06 |
2016-11-15 |
Genzyme Corp |
Composiciones y metodos de tratamiento y prevencion de degeneracion macular.
|
CA2938731A1
(en)
|
2014-02-08 |
2015-08-13 |
Genentech, Inc. |
Methods of treating alzheimer's disease
|
AU2015214058B2
(en)
|
2014-02-08 |
2020-07-09 |
Genentech, Inc. |
Methods of treating Alzheimer's Disease
|
BR112016018313A8
(pt)
|
2014-02-10 |
2018-06-12 |
Igm Biosciences Inc |
Moléculas de ligação multiespecíficas iga
|
MX2016010433A
(es)
|
2014-02-12 |
2016-09-22 |
Genentech Inc |
Anticuerpos anti-jagged1 y metodos de uso.
|
UA117608C2
(uk)
|
2014-02-21 |
2018-08-27 |
Дженентек, Інк. |
Спосіб лікування еозинофільного захворювання у пацієнта шляхом застосування біспецифічного анти-il-13/il-17 антитіла
|
AU2015218633A1
(en)
|
2014-02-21 |
2016-09-01 |
Abbvie Stemcentrx Llc |
Anti-DLL3 antibodies and drug conjugates for use in melanoma
|
MX2016011155A
(es)
|
2014-02-28 |
2017-02-22 |
Merus Nv |
Anticuerpo que une erbb-2 y erbb-3.
|
US9732154B2
(en)
|
2014-02-28 |
2017-08-15 |
Janssen Biotech, Inc. |
Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
|
CA2941030A1
(en)
|
2014-02-28 |
2015-09-03 |
Merus N.V. |
Antibodies that bind egfr and erbb3
|
EP3116999B1
(en)
|
2014-03-14 |
2021-09-15 |
F. Hoffmann-La Roche AG |
Methods and compositions for secretion of heterologous polypeptides
|
WO2015138920A1
(en)
|
2014-03-14 |
2015-09-17 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
WO2015142675A2
(en)
|
2014-03-15 |
2015-09-24 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor
|
EP3119425B1
(en)
|
2014-03-15 |
2020-09-23 |
Novartis AG |
Regulatable chimeric antigen receptor
|
US20170107294A1
(en)
|
2014-03-21 |
2017-04-20 |
Nordlandssykehuset Hf |
Anti-cd14 antibodies and uses thereof
|
WO2015143414A2
(en)
|
2014-03-21 |
2015-09-24 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals that make single domain binding proteins
|
WO2015148531A1
(en)
|
2014-03-24 |
2015-10-01 |
Genentech, Inc. |
Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
|
AR099856A1
(es)
|
2014-03-27 |
2016-08-24 |
Genentech Inc |
Métodos para diagnosticar y tratar la enfermedad de intestino inflamado
|
EP3129767B1
(en)
|
2014-03-27 |
2021-09-01 |
Academia Sinica |
Reactive labelling compounds and uses thereof
|
CN111410691B
(zh)
|
2014-03-28 |
2024-02-13 |
Xencor公司 |
结合至cd38和cd3的双特异性抗体
|
PL3126394T3
(pl)
|
2014-03-31 |
2020-05-18 |
F.Hoffmann-La Roche Ag |
Przeciwciała anty-OX40 i sposoby stosowania
|
AU2015241038A1
(en)
|
2014-03-31 |
2016-10-13 |
Genentech, Inc. |
Combination therapy comprising anti-angiogenesis agents and OX40 binding agonists
|
US20170022291A1
(en)
|
2014-04-01 |
2017-01-26 |
Adimab, Llc |
Multispecific antibody analogs comprising a common light chain, and methods of their preparation and use
|
JP6666262B2
(ja)
|
2014-04-02 |
2020-03-13 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
多重特異性抗体の軽鎖誤対合を検出するための方法
|
UA117289C2
(uk)
|
2014-04-02 |
2018-07-10 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифічне антитіло
|
WO2015152908A1
(en)
|
2014-04-02 |
2015-10-08 |
U.S. Army Medical Research Institute Of Infectious Diseases |
Rapid dual direct fluorescent antibody assay for the identification of bacillus anthracis
|
ES2900898T3
(es)
|
2014-04-07 |
2022-03-18 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos biespecíficos inmunoactivadores
|
DK3129470T3
(da)
|
2014-04-07 |
2021-07-05 |
Novartis Ag |
Behandling af cancer ved anvendelse af anti-CD19-kimær antigenreceptor
|
EP3131584B1
(en)
|
2014-04-16 |
2022-01-12 |
Biocon Limited |
Stable protein formulations comprising a molar excess of sorbitol
|
WO2015161267A2
(en)
|
2014-04-18 |
2015-10-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
Humanized and chimeric monoclonal antibodies to cd99
|
WO2015164615A1
(en)
|
2014-04-24 |
2015-10-29 |
University Of Oslo |
Anti-gluten antibodies and uses thereof
|
SG11201607070VA
(en)
|
2014-05-02 |
2016-11-29 |
Momenta Pharmaceuticals Inc |
Compositions and methods related to engineered fc constructs
|
CN106471117A
(zh)
|
2014-05-06 |
2017-03-01 |
豪夫迈·罗氏有限公司 |
使用哺乳动物细胞产生异多聚体蛋白
|
CA2947157A1
(en)
|
2014-05-13 |
2015-11-19 |
Chugai Seiyaku Kabushiki Kaisha |
T cell-redirected antigen-binding molecule for cells having immunosuppression function
|
KR102246800B1
(ko)
|
2014-05-13 |
2021-04-30 |
바이오아트라, 인코퍼레이티드 |
조건부 활성 생체 단백질
|
ES2936810T3
(es)
|
2014-05-16 |
2023-03-22 |
Pfizer |
Anticuerpos biespecíficos con interfaces CH1-CL de ingeniería
|
JP2017522861A
(ja)
|
2014-05-22 |
2017-08-17 |
ジェネンテック, インコーポレイテッド |
抗gpc3抗体及びイムノコンジュゲート
|
WO2015179835A2
(en)
|
2014-05-23 |
2015-11-26 |
Genentech, Inc. |
Mit biomarkers and methods using the same
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
CA2950423A1
(en)
|
2014-05-27 |
2015-12-03 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
CN106661099A
(zh)
|
2014-05-27 |
2017-05-10 |
中央研究院 |
抗her2醣抗体及其用途
|
KR20240096599A
(ko)
|
2014-05-27 |
2024-06-26 |
아카데미아 시니카 |
항-cd20 글리코항체 및 이의 용도
|
EP3107938B1
(en)
|
2014-05-28 |
2022-05-04 |
Zymeworks Inc. |
Modified antigen binding polypeptide constructs and uses thereof
|
WO2015184001A1
(en)
|
2014-05-28 |
2015-12-03 |
Academia Sinica |
Anti-tnf-alpha glycoantibodies and uses thereof
|
GB201409558D0
(en)
|
2014-05-29 |
2014-07-16 |
Ucb Biopharma Sprl |
Method
|
RU2718692C2
(ru)
|
2014-05-29 |
2020-04-13 |
Мэкроудженикс, Инк. |
Триспецифичные связывающие молекулы, которые специфически связывают антигены множества злокачественных опухолей, и способы их применения
|
US11123426B2
(en)
|
2014-06-11 |
2021-09-21 |
The Trustees Of Dartmouth College |
Use of vista agonists and antagonists to suppress or enhance humoral immunity
|
WO2015191715A1
(en)
|
2014-06-11 |
2015-12-17 |
Genentech, Inc. |
Anti-lgr5 antibodies and uses thereof
|
WO2015191986A1
(en)
|
2014-06-13 |
2015-12-17 |
Genentech, Inc. |
Methods of treating and preventing cancer drug resistance
|
TWI695011B
(zh)
|
2014-06-18 |
2020-06-01 |
美商梅爾莎納醫療公司 |
抗her2表位之單株抗體及其使用之方法
|
TWI713453B
(zh)
|
2014-06-23 |
2020-12-21 |
美商健生生物科技公司 |
干擾素α及ω抗體拮抗劑
|
EP3161001A2
(en)
|
2014-06-25 |
2017-05-03 |
Novartis AG |
Antibodies specific for il-17a fused to hyaluronan binding peptide tags
|
US20170327553A1
(en)
|
2014-06-25 |
2017-11-16 |
Novartis Ag |
Compositions and methods for long acting proteins
|
WO2015198243A2
(en)
|
2014-06-25 |
2015-12-30 |
Novartis Ag |
Compositions and methods for long acting proteins
|
GB201411320D0
(en)
|
2014-06-25 |
2014-08-06 |
Ucb Biopharma Sprl |
Antibody construct
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
AR100978A1
(es)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
|
JP6654581B2
(ja)
|
2014-06-26 |
2020-02-26 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
抗brdu抗体および使用方法
|
TW201623329A
(zh)
|
2014-06-30 |
2016-07-01 |
亞佛瑞司股份有限公司 |
針對骨調素截斷變異體的疫苗及單株抗體暨其用途
|
EP3164417A1
(en)
|
2014-07-01 |
2017-05-10 |
Pfizer Inc. |
Bispecific heterodimeric diabodies and uses thereof
|
CN107074925B
(zh)
|
2014-07-10 |
2021-08-24 |
阿费里斯股份公司 |
用于预防和/或治疗亨廷顿氏病的物质和方法
|
SG11201700207WA
(en)
|
2014-07-11 |
2017-02-27 |
Genentech Inc |
Anti-pd-l1 antibodies and diagnostic uses thereof
|
KR20170029490A
(ko)
|
2014-07-11 |
2017-03-15 |
제넨테크, 인크. |
노치 경로 억제
|
GB201412658D0
(en)
|
2014-07-16 |
2014-08-27 |
Ucb Biopharma Sprl |
Molecules
|
GB201412659D0
(en)
|
2014-07-16 |
2014-08-27 |
Ucb Biopharma Sprl |
Molecules
|
EP3193915A1
(en)
|
2014-07-21 |
2017-07-26 |
Novartis AG |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
JP7054622B2
(ja)
|
2014-07-21 |
2022-04-14 |
ノバルティス アーゲー |
ヒト化抗bcmaキメラ抗原受容体を使用した癌の処置
|
BR112017001242A2
(pt)
|
2014-07-21 |
2017-12-05 |
Novartis Ag |
tratamento de câncer usando um receptor antigênico quimérico a cd33
|
AR101262A1
(es)
|
2014-07-26 |
2016-12-07 |
Regeneron Pharma |
Plataforma de purificación para anticuerpos biespecíficos
|
AP2016009663A0
(en)
|
2014-07-30 |
2016-12-31 |
Ngm Biopharmaceuticals Inc |
Compositions and methods of use for treating metabolic disorders
|
EP4205749A1
(en)
|
2014-07-31 |
2023-07-05 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing cells
|
EP2982692A1
(en)
|
2014-08-04 |
2016-02-10 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
MX2017001556A
(es)
|
2014-08-04 |
2017-05-15 |
Hoffmann La Roche |
Moleculas biespecificas de union a antigeno activadoras de celulas t.
|
EP4066859A1
(en)
|
2014-08-08 |
2022-10-05 |
Alector LLC |
Anti-trem2 antibodies and methods of use thereof
|
JP6919118B2
(ja)
|
2014-08-14 |
2021-08-18 |
ノバルティス アーゲー |
GFRα−4キメラ抗原受容体を用いる癌の治療
|
SG11201700770PA
(en)
|
2014-08-19 |
2017-03-30 |
Novartis Ag |
Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
|
KR20170067729A
(ko)
|
2014-08-22 |
2017-06-16 |
소렌토 쎄라퓨틱스, 인코포레이티드 |
Cxcr3에 결합하는 항원 결합 단백질
|
US20170275344A1
(en)
|
2014-08-26 |
2017-09-28 |
Compugen Ltd. |
Polypeptides and uses thereof as a drug for treatment of autoimmune disorders
|
US11111288B2
(en)
|
2014-08-28 |
2021-09-07 |
Bioatla, Inc. |
Conditionally active chimeric antigen receptors for modified t-cells
|
ES2913865T3
(es)
|
2014-08-28 |
2022-06-06 |
Bioatla Inc |
Receptores de antígeno quimérico condicionalmente activos para células T modificadas
|
TW201617368A
(zh)
|
2014-09-05 |
2016-05-16 |
史坦森特瑞斯公司 |
新穎抗mfi2抗體及使用方法
|
KR102422375B1
(ko)
|
2014-09-08 |
2022-07-18 |
아카데미아 시니카 |
당지질을 사용한 인간 iNKT 세포 활성화
|
SG11201701867SA
(en)
|
2014-09-09 |
2017-04-27 |
Janssen Biotech Inc |
Combination therapies with anti-cd38 antibodies
|
TW201625688A
(zh)
|
2014-09-12 |
2016-07-16 |
建南德克公司 |
經半胱胺酸改造之抗體及接合物
|
MX2017003022A
(es)
|
2014-09-12 |
2017-05-12 |
Genentech Inc |
Anticuerpos anti-cll-1 e inmunoconjugados.
|
EP3191518B1
(en)
|
2014-09-12 |
2020-01-15 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
CN114106185A
(zh)
|
2014-09-12 |
2022-03-01 |
基因泰克公司 |
抗her2抗体和免疫缀合物
|
US20160137727A1
(en)
|
2014-09-15 |
2016-05-19 |
Genentech, Inc. |
Antibody formulations
|
MX2017003247A
(es)
|
2014-09-15 |
2017-11-30 |
Amgen Inc |
Proteina de union a antigenos, bi-especificos del receptor anti-cgrp/receptor pac1 y usos de las mismas.
|
PL3194443T3
(pl)
|
2014-09-17 |
2022-01-31 |
Novartis Ag |
Nakierowywanie komórek cytotoksycznych za pośrednictwem receptorów chimerycznych do immunoterapii adoptywnej
|
WO2016044396A1
(en)
|
2014-09-17 |
2016-03-24 |
Genentech, Inc. |
Immunoconjugates comprising anti-her2 antibodies and pyrrolobenzodiazepines
|
WO2016044745A1
(en)
|
2014-09-19 |
2016-03-24 |
Regeneron Pharmaceuticals, Inc. |
Chimeric antigen receptors
|
EP3197915A4
(en)
|
2014-09-22 |
2018-12-19 |
Intrinsic Lifesciences LLC |
Humanized anti-hepcidin antibodies and uses thereof
|
WO2016049214A1
(en)
|
2014-09-23 |
2016-03-31 |
Genentech, Inc. |
METHOD OF USING ANTI-CD79b IMMUNOCONJUGATES
|
WO2016046778A2
(en)
|
2014-09-25 |
2016-03-31 |
Amgen Inc |
Protease-activatable bispecific proteins
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
WO2016054101A1
(en)
|
2014-09-29 |
2016-04-07 |
Duke University |
Bispecific molecules comprising an hiv-1 envelope targeting arm
|
BR112017006602A2
(pt)
|
2014-10-01 |
2017-12-19 |
Medimmune Llc |
método de conjugação de um polipeptídeo
|
CA2963692A1
(en)
|
2014-10-09 |
2016-04-14 |
Engmab Ag |
Bispecific antibodies against cd3epsilon and ror1
|
EP4245376A3
(en)
|
2014-10-14 |
2023-12-13 |
Novartis AG |
Antibody molecules to pd-l1 and uses thereof
|
DK3207130T3
(da)
|
2014-10-14 |
2019-11-11 |
Halozyme Inc |
Sammensætninger af Adenosin Deaminase-2 (ADA2), varianter deraf og fremgangsmåder til anvendelse af samme
|
WO2016061389A2
(en)
|
2014-10-16 |
2016-04-21 |
Genentech, Inc. |
Anti-alpha-synuclein antibodies and methods of use
|
NZ731491A
(en)
|
2014-10-23 |
2021-12-24 |
Kira Biotech Pty Ltd |
Cd83 binding proteins and uses thereof
|
US10584175B2
(en)
|
2014-10-23 |
2020-03-10 |
La Trobe University |
FN14-binding proteins and uses thereof
|
TN2017000113A1
(en)
|
2014-10-31 |
2018-07-04 |
Ngm Biopharmaceuticals Inc |
Compositions and methods of use for treating metabolic disorders
|
ES2808153T3
(es)
|
2014-10-31 |
2021-02-25 |
Mereo Biopharma 5 Inc |
Terapia de combinación para tratamiento de enfermedad
|
EP3215850B1
(en)
|
2014-11-03 |
2019-07-03 |
F. Hoffmann-La Roche AG |
Assays for detecting t cell immune subsets and methods of use thereof
|
SG11201703521UA
(en)
|
2014-11-03 |
2017-05-30 |
Genentech Inc |
Methods and biomarkers for predicting efficacy and evaluation of an ox40 agonist treatment
|
US11773166B2
(en)
|
2014-11-04 |
2023-10-03 |
Ichnos Sciences SA |
CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production
|
CA2966558C
(en)
|
2014-11-05 |
2024-03-12 |
Genentech, Inc. |
Methods of producing two chain proteins in bacteria
|
BR112017009297B1
(pt)
|
2014-11-05 |
2024-02-15 |
Annexon, Inc |
Anticorpos antifator de complemento c1q humanizados, composição farmacêutica e kit compreendendo os mesmos, uso terapêutico destes,polinucleotídeo isolado, célula hospedeira isolada, bem como métodos in vitro para detectar sinapses
|
AU2015342964B2
(en)
|
2014-11-05 |
2021-06-24 |
Genentech, Inc. |
Methods of producing two chain proteins in bacteria
|
EP3842453A1
(en)
|
2014-11-06 |
2021-06-30 |
F. Hoffmann-La Roche AG |
Fc-region variants with modified fcrn- and protein a-binding properties
|
DK3215528T3
(da)
|
2014-11-06 |
2019-10-07 |
Hoffmann La Roche |
Fc-regionvarianter med modificeret FcRn-binding og anvendelsesfremgangsmåder
|
WO2016073157A1
(en)
|
2014-11-06 |
2016-05-12 |
Genentech, Inc. |
Anti-ang2 antibodies and methods of use thereof
|
DK3215530T3
(da)
|
2014-11-07 |
2019-11-25 |
Sesen Bio Inc |
Forbedrede il-6 antistoffer
|
WO2016073894A1
(en)
|
2014-11-07 |
2016-05-12 |
Eleven Biotherapeutics, Inc. |
Therapeutic agents with increased ocular retention
|
CA2960297A1
(en)
|
2014-11-10 |
2016-05-19 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
EP3217787B1
(en)
|
2014-11-10 |
2019-04-17 |
F.Hoffmann-La Roche Ag |
Animal model for nephropathy and agents for treating the same
|
RS60201B1
(sr)
|
2014-11-14 |
2020-06-30 |
Hoffmann La Roche |
Antigen vezujući molekuli koji sadrže trimer liganda familije tnf
|
SG11201703605QA
(en)
|
2014-11-17 |
2017-06-29 |
Genentech Inc |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
JP6993228B2
(ja)
|
2014-11-19 |
2022-03-03 |
ジェネンテック, インコーポレイテッド |
抗トランスフェリン受容体/抗bace1多重特異性抗体および使用方法
|
EP3221364B1
(en)
|
2014-11-19 |
2020-12-16 |
Genentech, Inc. |
Antibodies against bace1 and use thereof for neural disease immunotherapy
|
WO2016081643A1
(en)
|
2014-11-19 |
2016-05-26 |
Genentech, Inc. |
Anti-transferrin receptor antibodies and methods of use
|
WO2016079708A1
(en)
|
2014-11-19 |
2016-05-26 |
Nestec S.A. |
Antibodies against serotonin, tryptophan and kynurenine metabolites and uses thereof
|
EP3023437A1
(en)
|
2014-11-20 |
2016-05-25 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
LT3789402T
(lt)
|
2014-11-20 |
2022-09-26 |
F. Hoffmann-La Roche Ag |
Kompleksinė terapija, naudojant t ląsteles aktyvinančias bispecifines antigeną surišančias molekules ir pd-1 ašį surišančius antagonistus
|
ES2808853T3
(es)
|
2014-11-20 |
2021-03-02 |
Hoffmann La Roche |
Cadenas ligeras comunes y procedimientos de uso
|
US11033637B2
(en)
|
2014-11-21 |
2021-06-15 |
University Of Maryland, Baltimore |
Targeted structure-specific particulate delivery systems
|
LT3223845T
(lt)
|
2014-11-26 |
2021-08-25 |
Xencor, Inc. |
Heterodimeriniai antikūnai, kurie suriša cd3 ir cd20
|
WO2016086196A2
(en)
|
2014-11-26 |
2016-06-02 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cd38
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
WO2016082044A1
(en)
|
2014-11-27 |
2016-06-02 |
Zymeworks Inc. |
Methods of using bispecific antigen-binding constructs targeting her2
|
WO2016087514A1
(en)
|
2014-12-02 |
2016-06-09 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Anti-mutant calreticulin antibodies and their use in the diagnosis and therapy of myeloid malignancies
|
WO2016087416A1
(en)
|
2014-12-03 |
2016-06-09 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
WO2016090347A1
(en)
|
2014-12-05 |
2016-06-09 |
Immunext, Inc. |
Identification of vsig8 as the putative vista receptor and its use thereof to produce vista/vsig8 modulators
|
MA40938A
(fr)
|
2014-12-05 |
2017-10-11 |
Hoffmann La Roche |
Anticorps anti-cd79b et méthodes d'utilisation desdits anticorps
|
MX2017007491A
(es)
|
2014-12-10 |
2018-05-04 |
Genentech Inc |
Anticuerpos del receptor de la barrera hematoencefálica y métodos para su uso.
|
US11001625B2
(en)
|
2014-12-10 |
2021-05-11 |
Tufts University |
VHH based binding antibodies for anthrax and botulinum toxins and methods of making and using therefor
|
US20160168237A1
(en)
|
2014-12-12 |
2016-06-16 |
Alexion Pharmaceuticals, Inc. |
Method for treating a complement mediated disorder caused by an infectious agent in a patient
|
KR20170094787A
(ko)
|
2014-12-18 |
2017-08-21 |
에프. 호프만-라 로슈 아게 |
Cdc 유발 항체를 측정하기 위한 검정 및 방법
|
KR102650420B1
(ko)
|
2014-12-19 |
2024-03-21 |
추가이 세이야쿠 가부시키가이샤 |
항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
|
WO2016094962A1
(en)
|
2014-12-19 |
2016-06-23 |
Monash University |
Il-21 antibodies
|
EA201791366A1
(ru)
|
2014-12-19 |
2018-02-28 |
Чугаи Сейяку Кабусики Кайся |
Антитела к c5 и способы их применения
|
EP3233907B1
(en)
|
2014-12-19 |
2021-03-03 |
Genmab A/S |
Rodent bispecific heterodimeric proteins
|
EP3237449A2
(en)
|
2014-12-22 |
2017-11-01 |
Xencor, Inc. |
Trispecific antibodies
|
CA3197849A1
(en)
|
2014-12-29 |
2016-07-07 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
EA037654B1
(ru)
|
2014-12-30 |
2021-04-27 |
Селджин Корпорейшн |
Анти-cd47-антитела и их применения
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
WO2016117346A1
(en)
|
2015-01-22 |
2016-07-28 |
Chugai Seiyaku Kabushiki Kaisha |
A combination of two or more anti-c5 antibodies and methods of use
|
TWI726862B
(zh)
|
2015-01-23 |
2021-05-11 |
法商賽諾菲公司 |
特異性結合cd3及/或cd123之抗-cd3抗體,抗-cd123抗體及雙特異性抗體
|
AU2015378564A1
(en)
|
2015-01-24 |
2017-07-13 |
Academia Sinica |
Novel glycan conjugates and methods of use thereof
|
CN107430127B
(zh)
|
2015-01-24 |
2020-08-28 |
中央研究院 |
癌症标记及其使用方法
|
KR102329836B1
(ko)
|
2015-01-26 |
2021-11-19 |
셀렉티스 |
암 면역치료를 위한 항-CLL1 특이적 단일-체인 키메라 항원 수용체들(scCARS)
|
WO2016123329A2
(en)
|
2015-01-28 |
2016-08-04 |
Genentech, Inc. |
Gene expression markers and treatment of multiple sclerosis
|
AU2015380397B2
(en)
|
2015-01-31 |
2021-10-21 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for T cell delivery of therapeutic molecules
|
US11161907B2
(en)
|
2015-02-02 |
2021-11-02 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
JP2018512597A
(ja)
|
2015-02-04 |
2018-05-17 |
ジェネンテック, インコーポレイテッド |
突然変異体スムースンド及びその使用方法
|
US9969800B2
(en)
|
2015-02-05 |
2018-05-15 |
Chugai Seiyaku Kabushiki Kaisha |
IL-8 antibodies
|
JP6917902B2
(ja)
|
2015-02-13 |
2021-08-11 |
ソレント・セラピューティクス・インコーポレイテッド |
Ctla4に結合する抗体医薬
|
AR103782A1
(es)
|
2015-02-26 |
2017-05-31 |
Genentech Inc |
ANTAGONISTAS DE INTEGRINA b7 Y MÉTODOS DE TRATAMIENTO DE LA ENFERMEDAD DE CROHN
|
CA2972393A1
(en)
|
2015-02-27 |
2016-09-01 |
Chugai Seiyaku Kabushiki Kaisha |
Composition for treating il-6-related diseases
|
WO2016141387A1
(en)
|
2015-03-05 |
2016-09-09 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
AR103852A1
(es)
|
2015-03-06 |
2017-06-07 |
Genentech Inc |
DsbA Y DsbC ULTRAPURIFICADOS Y SUS MÉTODOS DE PREPARACIÓN Y USO
|
IL254403B
(en)
|
2015-03-09 |
2022-09-01 |
argenx BV |
Methods for lowering the amount of fc-containing substances in the serum by using fcrn antibodies
|
JP6394444B2
(ja)
*
|
2015-03-10 |
2018-09-26 |
株式会社デンソー |
ブラシレスモータ
|
MX2017011600A
(es)
|
2015-03-10 |
2018-06-13 |
Sorrento Therapeutics Inc |
Terapeuticos de anticuerpo que enlazan antigeno de membrana especifico de prostata.
|
CN107430117A
(zh)
|
2015-03-16 |
2017-12-01 |
豪夫迈·罗氏有限公司 |
检测和定量IL‑13的方法和在诊断和治疗Th2相关疾病中的用途
|
WO2016146833A1
(en)
|
2015-03-19 |
2016-09-22 |
F. Hoffmann-La Roche Ag |
Biomarkers for nad(+)-diphthamide adp ribosyltransferase resistance
|
CN107438622A
(zh)
|
2015-03-19 |
2017-12-05 |
瑞泽恩制药公司 |
选择结合抗原的轻链可变区的非人动物
|
RS61438B1
(sr)
|
2015-03-31 |
2021-03-31 |
Medimmune Ltd |
Novi oblik il33, mutirani oblici il33, antitela, testovi i postupci za njihovu upotrebu
|
CN114751989A
(zh)
|
2015-03-31 |
2022-07-15 |
豪夫迈·罗氏有限公司 |
包含三聚体tnf家族配体的抗原结合分子
|
US11142587B2
(en)
|
2015-04-01 |
2021-10-12 |
Chugai Seiyaku Kabushiki Kaisha |
Method for producing polypeptide hetero-oligomer
|
SG10201913158PA
(en)
|
2015-04-03 |
2020-02-27 |
Eureka Therapeutics Inc |
Constructs targeting afp peptide/mhc complexes and uses thereof
|
CN116327915A
(zh)
|
2015-04-03 |
2023-06-27 |
佐马技术有限公司 |
使用TGF-β抑制剂和PD-1抑制剂治疗癌症
|
MA41919A
(fr)
|
2015-04-06 |
2018-02-13 |
Acceleron Pharma Inc |
Hétéromultimères alk4:actriib et leurs utilisations
|
JP7055636B2
(ja)
|
2015-04-06 |
2022-04-18 |
アクセルロン ファーマ インコーポレイテッド |
ALK7:ActRIIBヘテロ多量体およびその使用
|
BR112017021536A2
(pt)
|
2015-04-06 |
2018-07-03 |
Harvard College |
composições e métodos para o condicionamento não mieloablativo
|
CN113683708A
(zh)
|
2015-04-06 |
2021-11-23 |
阿塞勒隆制药公司 |
单臂i型和ii型受体融合蛋白和其用途
|
IL254887B2
(en)
|
2015-04-07 |
2023-11-01 |
Alector Llc |
Anti-sortilin antibodies and methods of using them
|
AU2016246695A1
(en)
|
2015-04-07 |
2017-10-26 |
Genentech, Inc. |
Antigen binding complex having agonistic activity and methods of use
|
ES2927119T3
(es)
|
2015-04-08 |
2022-11-02 |
Sorrento Therapeutics Inc |
Productos terapéuticos de anticuerpos que se unen a CD38
|
HUE059218T2
(hu)
|
2015-04-08 |
2022-11-28 |
Novartis Ag |
CD20-terápiák, CD22-terápiák és kombinációs terápiák CD19 kiméra antigénreceptort (CAR-t) expresszáló sejttel
|
WO2016164708A1
(en)
|
2015-04-10 |
2016-10-13 |
Adimab, Llc |
Methods for purifying heterodimeric multispecific antibodies from parental homodimeric antibody species
|
CA2982996A1
(en)
|
2015-04-17 |
2016-10-20 |
David Maxwell Barrett |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
KR20170138494A
(ko)
|
2015-04-17 |
2017-12-15 |
엘살리스 비오떼끄 |
항-tyr03 항체 및 이의 용도
|
MX2017013383A
(es)
|
2015-04-20 |
2017-12-07 |
Tolero Pharmaceuticals Inc |
Prediccion de respuesta a alvocidib mediante perfilado mitocondrial.
|
WO2016172583A1
(en)
|
2015-04-23 |
2016-10-27 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
SI3286315T1
(sl)
|
2015-04-24 |
2021-09-30 |
F. Hoffmann-La Roche Ag |
Postopek identifikacije bakterij, ki obsegajo vezavne polipeptide
|
JP6952605B2
(ja)
|
2015-04-24 |
2021-10-20 |
ジェネンテック, インコーポレイテッド |
多特異性抗原結合タンパク質
|
CA2983022C
(en)
|
2015-04-27 |
2023-03-07 |
Dana-Farber Cancer Institute, Inc. |
High throughput bh3 profiling: a rapid and scalable technology to bh3 profile on low numbers of cells
|
US12011480B2
(en)
|
2015-05-06 |
2024-06-18 |
Uti Limited Partnership |
Nanoparticle compositions for sustained therapy
|
MA41279A
(fr)
|
2015-05-08 |
2021-04-28 |
Xencor Inc |
Anticorps hétérodimériques se liant aux antigènes cd3 et tumoraux
|
WO2016183104A1
(en)
|
2015-05-11 |
2016-11-17 |
Genentech, Inc. |
Compositions and methods of treating lupus nephritis
|
IL295002A
(en)
|
2015-05-12 |
2022-09-01 |
Genentech Inc |
Therapeutic and diagnostic methods for cancer containing a pd–l1 binding antagonist
|
EP3447075B1
(en)
|
2015-05-15 |
2023-08-09 |
The General Hospital Corporation |
Antagonistic anti-tumor necrosis factor receptor superfamily antibodies
|
TR201911032T4
(tr)
|
2015-05-18 |
2019-08-21 |
Tolero Pharmaceuticals Inc |
Artırılmış biyoyararlanıma sahip alvocıdıb ön ilaçları.
|
CN114634943A
(zh)
|
2015-05-18 |
2022-06-17 |
T细胞受体治疗公司 |
使用融合蛋白对tcr重编程的组合物和方法
|
BR112017024877A2
(pt)
|
2015-05-20 |
2019-09-17 |
Janssen Biotech, Inc. |
anticorpo anti-cd38 e seu uso no tratamento de amiloidose de cadeia leve e outras malignidades hematológicas positivas para cd38
|
AU2016263808B2
(en)
|
2015-05-21 |
2019-01-03 |
Harpoon Therapeutics, Inc. |
Trispecific binding proteins and methods of use
|
EP3303400B1
(en)
|
2015-05-28 |
2020-09-09 |
Genentech, Inc. |
Cell-based assay for detecting anti-cd3 homodimers
|
AR105618A1
(es)
|
2015-05-29 |
2017-10-25 |
Genentech Inc |
Metilación del promotor del ligando al receptor de muerte programada (pd-l1) en cáncer
|
PL3303632T5
(pl)
|
2015-05-29 |
2023-07-03 |
F. Hoffmann-La Roche Ag |
Terapeutyczne i diagnostyczne sposoby stosowane w nowotworze
|
CN107771182A
(zh)
|
2015-05-29 |
2018-03-06 |
豪夫迈·罗氏有限公司 |
人源化抗埃博拉病毒糖蛋白抗体和使用方法
|
WO2016196679A1
(en)
|
2015-06-02 |
2016-12-08 |
Genentech, Inc. |
Compositions and methods for using anti-il-34 antibodies to treat neurological diseases
|
TWI790642B
(zh)
|
2015-06-05 |
2023-01-21 |
美商建南德克公司 |
抗-tau抗體及使用方法
|
CN107750164A
(zh)
|
2015-06-08 |
2018-03-02 |
豪夫迈·罗氏有限公司 |
使用抗ox40抗体和pd‑1轴结合拮抗剂治疗癌症的方法
|
CN107810011A
(zh)
|
2015-06-08 |
2018-03-16 |
豪夫迈·罗氏有限公司 |
使用抗ox40抗体治疗癌症的方法
|
JP7497953B2
(ja)
|
2015-06-12 |
2024-06-11 |
アレクトル エルエルシー |
抗cd33抗体及びその使用方法
|
CN116063499A
(zh)
|
2015-06-12 |
2023-05-05 |
艾利妥 |
抗cd33抗体及其使用方法
|
CN108064246A
(zh)
|
2015-06-15 |
2018-05-22 |
基因泰克公司 |
抗体和免疫结合物
|
EP3310811B1
(en)
|
2015-06-16 |
2021-06-16 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
AU2016280102B2
(en)
|
2015-06-16 |
2022-06-16 |
Genentech, Inc. |
Humanized and affinity matured antibodies to FcRH5 and methods of use
|
TW201718647A
(zh)
|
2015-06-16 |
2017-06-01 |
建南德克公司 |
抗-cll-1抗體及使用方法
|
JP6896650B2
(ja)
|
2015-06-17 |
2021-06-30 |
ジェネンテック, インコーポレイテッド |
Pd−1軸結合アンタゴニスト及びタキサンを使用した局所進行性または転移性乳癌の治療方法
|
CA2986592A1
(en)
|
2015-06-17 |
2016-12-22 |
Genentech, Inc. |
Anti-her2 antibodies and methods of use
|
WO2016209921A1
(en)
|
2015-06-22 |
2016-12-29 |
Janssen Biotech, Inc. |
Combination therapies for heme malignancies with anti-cd38 antibodies and survivin inhibitors
|
PL3313441T3
(pl)
|
2015-06-24 |
2024-08-19 |
Janssen Biotech, Inc. |
Immunomodulacja i leczenie guzów litych przeciwciałami swoiście wiążącymi cd38
|
EP3744732A1
(en)
|
2015-06-24 |
2020-12-02 |
F. Hoffmann-La Roche AG |
Humanized anti-tau(ps422) antibodies and methods of use
|
MX2017016647A
(es)
|
2015-06-24 |
2019-04-25 |
Janssen Pharmaceutica Nv |
Anticuerpos y fragmentos anti-vista.
|
US11536716B2
(en)
|
2015-06-25 |
2022-12-27 |
Hoffmann-La Roche Inc. |
Cell based assay for determining antibody or ligand binding and function
|
EP3313878B1
(en)
|
2015-06-29 |
2021-09-15 |
Ventana Medical Systems, Inc. |
Materials and methods for performing histochemical assays for human pro-epiregulin and amphiregulin
|
CA2989936A1
(en)
|
2015-06-29 |
2017-01-05 |
Genentech, Inc. |
Type ii anti-cd20 antibody for use in organ transplantation
|
US11129903B2
(en)
|
2015-07-06 |
2021-09-28 |
Regeneron Pharmaceuticals, Inc. |
Multispecific antigen-binding molecules and uses thereof
|
US20180201693A1
(en)
|
2015-07-09 |
2018-07-19 |
Genmab A/S |
Bispecific and multispecific antibodies and method for isolation of such
|
SI3115376T1
(sl)
|
2015-07-10 |
2018-12-31 |
Merus N.V. |
Humana protitelesa, ki vežejo CD3
|
WO2017009712A1
(en)
|
2015-07-13 |
2017-01-19 |
Compugen Ltd. |
Hide1 compositions and methods
|
JP2018524373A
(ja)
|
2015-07-15 |
2018-08-30 |
ザイムワークス,インコーポレイテッド |
薬物がコンジュゲートされた二重特異性抗原結合コンストラクト
|
GB201601073D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibodies
|
GB201601075D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibodies molecules
|
GB201601077D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibody molecule
|
JP7146632B2
(ja)
|
2015-07-21 |
2022-10-04 |
ノバルティス アーゲー |
免疫細胞の有効性および増大を改善する方法
|
WO2017019897A1
(en)
|
2015-07-29 |
2017-02-02 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
PT3317301T
(pt)
|
2015-07-29 |
2021-07-09 |
Novartis Ag |
Terapias de associação compreendendo moléculas de anticorpo contra lag-3
|
EP3328418A1
(en)
|
2015-07-29 |
2018-06-06 |
Novartis AG |
Combination therapies comprising antibody molecules to pd-1
|
RS60030B1
(sr)
|
2015-08-03 |
2020-04-30 |
Engmab Sarl |
Monoklonska antitela protiv humanog antigena sazrevanja b ćelija (bcma)
|
AU2016301315C1
(en)
|
2015-08-03 |
2022-07-07 |
Sumitomo Pharma Oncology, Inc. |
Combination therapies for treatment of cancer
|
TW202340452A
(zh)
|
2015-08-04 |
2023-10-16 |
美商再生元醫藥公司 |
補充牛磺酸之細胞培養基及用法
|
MX2018001522A
(es)
|
2015-08-05 |
2018-03-15 |
Janssen Biotech Inc |
Anticuerpos anti-cd154 y metodos de uso de estos.
|
SI3331902T1
(sl)
|
2015-08-07 |
2021-09-30 |
ALX Oncology Inc. |
Konstrukti z domeno SIRP-alfa ali njegove različice
|
EA034582B1
(ru)
|
2015-08-07 |
2020-02-21 |
АЭлЭкс ОНКОЛОДЖИ ИНК. |
Конструкции варианта sirp-альфа и их применение
|
EP4137158A1
(en)
|
2015-08-07 |
2023-02-22 |
Imaginab, Inc. |
Antigen binding constructs to target molecules
|
WO2017027392A1
(en)
|
2015-08-07 |
2017-02-16 |
Novartis Ag |
Treatment of cancer using chimeric cd3 receptor proteins
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
AU2016312259B2
(en)
|
2015-08-26 |
2018-12-06 |
Bison Therapeutics Inc. |
Multispecific antibody platform and related methods
|
CN108135932A
(zh)
|
2015-08-28 |
2018-06-08 |
宾夕法尼亚大学董事会 |
表达嵌合细胞内信号传导分子的细胞的方法和组合物
|
CN108348551A
(zh)
|
2015-08-28 |
2018-07-31 |
宾夕法尼亚大学董事会 |
表达嵌合细胞内信号传导分子的细胞的方法和组合物
|
CN108137702B
(zh)
|
2015-08-28 |
2023-01-06 |
艾利妥 |
抗siglec-7抗体及其使用方法
|
JP2018528218A
(ja)
|
2015-09-11 |
2018-09-27 |
アンドリアン、ブルース |
組換えグリコシル化エクリズマブおよびエクリズマブ変異体
|
CA2997673A1
(en)
|
2015-09-15 |
2017-03-23 |
Board Of Regents, The University Of Texas System |
T-cell receptor (tcr)-binding antibodies and uses thereof
|
WO2017049004A1
(en)
|
2015-09-15 |
2017-03-23 |
Amgen Inc. |
Tetravalent bispecific and tetraspecific antigen binding proteins and uses thereof
|
TWI814162B
(zh)
|
2015-09-18 |
2023-09-01 |
日商中外製藥股份有限公司 |
Il-8結合抗體及其用途
|
KR20180053322A
(ko)
|
2015-09-21 |
2018-05-21 |
압테보 리서치 앤드 디벨롭먼트 엘엘씨 |
Cd3 결합 폴리펩타이드
|
EP3353206A1
(en)
|
2015-09-22 |
2018-08-01 |
Spring Bioscience Corporation |
Anti-ox40 antibodies and diagnostic uses thereof
|
WO2017053705A1
(en)
|
2015-09-23 |
2017-03-30 |
Oncomed Pharmaceuticals, Inc. |
Methods and compositions for treatment of cancer
|
MY191756A
(en)
|
2015-09-23 |
2022-07-14 |
Genentech Inc |
Optimized variants of anti-vegf antibodies
|
MX2018003533A
(es)
|
2015-09-24 |
2019-04-25 |
Abvitro Llc |
Composiciones de anticuerpo de virus de inmunodeficiencia humana (vih) y metodos de uso.
|
CN113956358A
(zh)
|
2015-09-25 |
2022-01-21 |
豪夫迈·罗氏有限公司 |
抗tigit抗体和使用方法
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
CN108026179A
(zh)
|
2015-10-02 |
2018-05-11 |
豪夫迈·罗氏有限公司 |
结合间皮素和cd3的双特异性t细胞活化性抗原结合分子
|
WO2017055392A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xcd44v6 bispecific t cell activating antigen binding molecules
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
WO2017055393A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xtim-3 bispecific t cell activating antigen binding molecules
|
WO2017055395A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xrob04 bispecific t cell activating antigen binding molecules
|
JP7239320B2
(ja)
*
|
2015-10-02 |
2023-03-14 |
エフ. ホフマン-ラ ロシュ アーゲー |
多重特異性抗体
|
CN108139394B
(zh)
|
2015-10-02 |
2020-10-30 |
豪夫迈·罗氏有限公司 |
用于确定同时结合的基于细胞的fret测定法
|
SI3356404T1
(sl)
|
2015-10-02 |
2021-11-30 |
F. Hoffmann-La Roche Ag |
Protitelesa proti PD1 in postopki uporabe
|
WO2017055385A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xgd2 bispecific t cell activating antigen binding molecules
|
EP3150637A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Multispecific antibodies
|
CN108602887B
(zh)
|
2015-10-02 |
2022-06-21 |
豪夫迈·罗氏有限公司 |
对共刺激性tnf受体特异性的双特异性抗体
|
EP3150636A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Tetravalent multispecific antibodies
|
JP2018533930A
(ja)
|
2015-10-02 |
2018-11-22 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性t細胞活性化抗原結合分子
|
WO2017055389A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Bispecific anti-ceaxcd3 t cell activating antigen binding molecules
|
JP6937746B2
(ja)
|
2015-10-02 |
2021-09-22 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性抗cd19×cd3t細胞活性化抗原結合分子
|
AU2016329126B2
(en)
|
2015-10-02 |
2023-04-13 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies specific for PD1 and TIM3
|
KR20180075537A
(ko)
|
2015-10-06 |
2018-07-04 |
제넨테크, 인크. |
다발성 경화증을 치료하기 위한 방법
|
CN108738323B
(zh)
|
2015-10-06 |
2023-05-26 |
艾利妥 |
抗trem2抗体及其使用方法
|
JP7074665B2
(ja)
|
2015-10-07 |
2022-05-24 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
共刺激tnf受容体に対する四価の二重特異性抗体発明の分野
|
US11203634B2
(en)
|
2015-10-07 |
2021-12-21 |
Alexion Pharmaceuticals, Inc. |
Methods of treating age-related macular degeneration in a patient comprising administering an anti-C5a antibody
|
GEP20217317B
(en)
|
2015-10-08 |
2021-11-10 |
Macrogenics Inc |
Combination therapy for the treatment of cancer
|
WO2017059551A1
(en)
|
2015-10-08 |
2017-04-13 |
Zymeworks Inc. |
Antigen-binding polypeptide constructs comprising kappa and lambda light chains and uses thereof
|
KR101851380B1
(ko)
|
2015-10-12 |
2018-04-23 |
아주대학교산학협력단 |
효모접합을 이용한 항체 ch3 도메인 이종이중체 돌연변이쌍 제조 방법 및 이에 의하여 제조된 ch3 돌연변이체 쌍
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
MA45326A
(fr)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation
|
CN108602888B
(zh)
|
2015-10-23 |
2022-10-04 |
美勒斯公司 |
抑制癌症生长的结合分子
|
CN117069855A
(zh)
|
2015-10-25 |
2023-11-17 |
赛诺菲 |
用于预防或治疗hiv感染的三特异性和/或三价结合蛋白
|
JP7060502B2
(ja)
|
2015-10-29 |
2022-04-26 |
アレクトル エルエルシー |
抗Siglec-9抗体及びその使用方法
|
EP3184547A1
(en)
|
2015-10-29 |
2017-06-28 |
F. Hoffmann-La Roche AG |
Anti-tpbg antibodies and methods of use
|
EP4015533A1
(en)
|
2015-10-29 |
2022-06-22 |
F. Hoffmann-La Roche AG |
Anti-variant fc-region antibodies and methods of use
|
WO2017075212A1
(en)
|
2015-10-30 |
2017-05-04 |
Genentech, Inc. |
Anti-htra1 antibodies and methods of use thereof
|
WO2017075173A2
(en)
|
2015-10-30 |
2017-05-04 |
Genentech, Inc. |
Anti-factor d antibodies and conjugates
|
CN116333125A
(zh)
|
2015-10-30 |
2023-06-27 |
银河生物技术有限责任公司 |
结合死亡受体4和死亡受体5的抗体
|
MA43187B1
(fr)
|
2015-11-03 |
2021-02-26 |
Janssen Biotech Inc |
Formulations sous-cutanée d'anticorps anti-cd38 et leurs utilisations
|
JP6998869B2
(ja)
|
2015-11-08 |
2022-02-04 |
ジェネンテック, インコーポレイテッド |
多重特異性抗体のスクリーニング方法
|
US11660340B2
(en)
|
2015-11-18 |
2023-05-30 |
Chugai Seiyaku Kabushiki Kaisha |
Combination therapy using T cell redirection antigen binding molecule against cell having immunosuppressing function
|
US11649293B2
(en)
|
2015-11-18 |
2023-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Method for enhancing humoral immune response
|
LT3380620T
(lt)
|
2015-11-23 |
2024-09-10 |
Novartis Ag |
Optimizuoti lentivirusiniai pernešimo vektoriai ir jų panaudojimas
|
CN106729743B
(zh)
|
2015-11-23 |
2021-09-21 |
四川科伦博泰生物医药股份有限公司 |
抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用
|
GB201521393D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl |
Antibodies
|
GB201521382D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl |
Antibodies
|
GB201521391D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl |
Antibodies
|
GB201521389D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl |
Method
|
GB201521383D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl And Ucb Celltech |
Method
|
US10227410B2
(en)
|
2015-12-07 |
2019-03-12 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and PSMA
|
EP4026848A1
(en)
|
2015-12-09 |
2022-07-13 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing the cytokine release syndrome
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
UA125611C2
(uk)
|
2015-12-14 |
2022-05-04 |
Макродженікс, Інк. |
Біспецифічні молекули, що мають імунореактивність відносно pd-1 і ctla-4, і способи їх застосування
|
CN106883297B
(zh)
*
|
2015-12-16 |
2019-12-13 |
苏州康宁杰瑞生物科技有限公司 |
基于ch3结构域的异二聚体分子、其制备方法及用途
|
WO2017106810A2
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Combination of c-met inhibitor with antibody molecule to pd-1 and uses thereof
|
WO2017106684A2
(en)
|
2015-12-17 |
2017-06-22 |
Janssen Biotech, Inc. |
Antibodies specifically binding hla-dr and their uses
|
WO2017106656A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
PE20240365A1
(es)
|
2015-12-18 |
2024-03-04 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos anti-c5 y metodos de uso
|
MX2018007781A
(es)
|
2015-12-28 |
2018-09-05 |
Chugai Pharmaceutical Co Ltd |
Metodo para promover la eficiencia de purificacion del polipeptido que contiene la region de fragmento cristalizable (fc).
|
CA3007419A1
(en)
|
2015-12-30 |
2017-07-06 |
Genentech, Inc. |
Formulations with reduced degradation of polysorbate
|
EP3397243A1
(en)
|
2015-12-30 |
2018-11-07 |
H. Hoffnabb-La Roche Ag |
Use of tryptophan derivatives for protein formulations
|
ES2944597T3
(es)
|
2015-12-30 |
2023-06-22 |
Novartis Ag |
Terapias con células efectoras inmunitarias de eficacia mejorada
|
PL3400246T3
(pl)
|
2016-01-08 |
2021-03-08 |
F. Hoffmann-La Roche Ag |
Sposoby leczenia nowotworów z dodatnim markerem cea z wykorzystaniem antagonistów wiążących oś pd-1 oraz przeciwciał dwuswoistych anty-cea/anty-cd3
|
CA3010678A1
(en)
|
2016-01-10 |
2017-07-20 |
Neotx Therapeutics Ltd. |
Methods and compositions for enhancing the potency of superantigen mediated cancer immunotherapy
|
CN108602883A
(zh)
|
2016-01-20 |
2018-09-28 |
基因泰克公司 |
用于阿尔茨海默氏病的高剂量治疗
|
US20210198368A1
(en)
|
2016-01-21 |
2021-07-01 |
Novartis Ag |
Multispecific molecules targeting cll-1
|
JP7438662B2
(ja)
|
2016-01-25 |
2024-02-27 |
ジェネンテック, インコーポレイテッド |
T細胞依存性二重特異的抗体をアッセイするための方法
|
CN108495653A
(zh)
|
2016-01-27 |
2018-09-04 |
免疫医疗有限责任公司 |
用于制备具有定义的糖基化模式抗体的方法
|
US10118963B2
(en)
|
2016-01-29 |
2018-11-06 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind PD-L1
|
CA3019952A1
(en)
|
2016-02-04 |
2017-08-10 |
Curis, Inc. |
Mutant smoothened and methods of using the same
|
MX2018009800A
(es)
|
2016-02-12 |
2018-11-09 |
Janssen Pharmaceutica Nv |
Anticuerpos y fragmentos anti-vista, usos de los mismos y procedimientos de identificacion de los mismos.
|
CN108718522A
(zh)
|
2016-02-23 |
2018-10-30 |
赛森生物股份有限公司 |
Il-6拮抗剂制剂及其用途
|
JP6821693B2
(ja)
|
2016-02-29 |
2021-01-27 |
ジェネンテック, インコーポレイテッド |
がんのための治療方法及び診断方法
|
JP2019513347A
(ja)
|
2016-03-04 |
2019-05-30 |
ノバルティス アーゲー |
複数のキメラ抗原受容体(car)分子を発現する細胞およびその使用
|
EP3423493A2
(en)
|
2016-03-04 |
2019-01-09 |
Alector LLC |
Anti-trem1 antibodies and methods of use thereof
|
JP2019515876A
(ja)
|
2016-03-08 |
2019-06-13 |
アカデミア シニカAcademia Sinica |
N−グリカンおよびそのアレイのモジュール合成のための方法
|
KR20180116215A
(ko)
|
2016-03-14 |
2018-10-24 |
추가이 세이야쿠 가부시키가이샤 |
암의 치료에 이용하기 위한 세포상해 유도 치료제
|
EP3430058A4
(en)
|
2016-03-15 |
2019-10-23 |
Generon (Shanghai) Corporation Ltd. |
MULTISPECIFIC FAB FUSION PROTEINS AND USES THEREOF
|
AU2017238172B2
(en)
|
2016-03-21 |
2024-06-27 |
Marengo Therapeutics, Inc. |
Multispecific and multifunctional molecules and uses thereof
|
PT3433280T
(pt)
|
2016-03-22 |
2023-06-15 |
Hoffmann La Roche |
Moléculas biespecíficas das células t ativadas pela protease
|
HUE061946T2
(hu)
|
2016-03-22 |
2023-09-28 |
Hoffmann La Roche |
Proteáz-aktivált T-sejt bispecifikus molekulák
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
CN108700598A
(zh)
|
2016-03-25 |
2018-10-23 |
豪夫迈·罗氏有限公司 |
多路总抗体和抗体缀合的药物量化测定法
|
SG11201808582RA
(en)
|
2016-03-28 |
2018-10-30 |
Incyte Corp |
Pyrrolotriazine compounds as tam inhibitors
|
EP3231813A1
(en)
|
2016-03-29 |
2017-10-18 |
F. Hoffmann-La Roche AG |
Trimeric costimulatory tnf family ligand-containing antigen binding molecules
|
JP7468992B2
(ja)
|
2016-03-29 |
2024-04-16 |
ヤンセン バイオテツク,インコーポレーテツド |
抗il12及び/又は-23抗体の増加した間隔投与による乾癬の処置
|
AU2017244108B2
(en)
|
2016-03-29 |
2021-03-18 |
University Of Southern California |
Chimeric antigen receptors targeting cancer
|
WO2017175058A1
(en)
|
2016-04-07 |
2017-10-12 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
KR20240036142A
(ko)
|
2016-04-13 |
2024-03-19 |
사노피 |
3특이성 및/또는 3가 결합 단백질
|
KR20180134378A
(ko)
|
2016-04-13 |
2018-12-18 |
사노피 |
3특이성 및/또는 3가 결합 단백질
|
WO2017180864A1
(en)
|
2016-04-14 |
2017-10-19 |
Genentech, Inc. |
Anti-rspo3 antibodies and methods of use
|
EP3442574A4
(en)
|
2016-04-15 |
2019-12-11 |
MacroGenics, Inc. |
NOVEL B7-H3 BINDING MOLECULES, THEIR ANTIBODY-MEDICINAL CONJUGATES AND METHODS OF USE
|
JP7527758B2
(ja)
|
2016-04-15 |
2024-08-05 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
Cd80バリアント免疫調節タンパク質およびその使用
|
KR102459684B1
(ko)
|
2016-04-15 |
2022-10-26 |
바이오아트라, 인코퍼레이티드 |
항 Axl항체 및 이의 면역접합체와 이것들의 용도
|
DK3443096T5
(da)
|
2016-04-15 |
2024-09-09 |
Novartis Ag |
Sammensætninger og fremgangsmåder til selektiv ekspression af kimære antigenreceptorer
|
MX2018012493A
(es)
|
2016-04-15 |
2019-06-06 |
Genentech Inc |
Métodos para controlar y tratar el cáncer.
|
CA3020848A1
(en)
|
2016-04-15 |
2017-10-19 |
Janssen Pharmaceuticals, Inc. |
Anti-human vista antibodies and use thereof
|
KR102536850B1
(ko)
|
2016-04-15 |
2023-05-26 |
알파인 이뮨 사이언시즈, 인코포레이티드 |
Icos 리간드 변이체 면역조절 단백질 및 그의 용도
|
CA3019921A1
(en)
|
2016-04-15 |
2017-10-19 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
US11016085B2
(en)
|
2016-04-25 |
2021-05-25 |
The Johns Hopkins University |
ZNT8 assays for drug development and pharmaceutical compositions
|
US11208632B2
(en)
|
2016-04-26 |
2021-12-28 |
R.P. Scherer Technologies, Llc |
Antibody conjugates and methods of making and using the same
|
WO2017190079A1
(en)
|
2016-04-28 |
2017-11-02 |
Regeneron Pharmaceuticals, Inc. |
Methods of making multispecific antigen-binding molecules
|
EP3889175A1
(en)
|
2016-05-02 |
2021-10-06 |
F. Hoffmann-La Roche AG |
The contorsbody - a single chain target binder
|
WO2017196902A2
(en)
|
2016-05-10 |
2017-11-16 |
Genentech, Inc. |
Methods of decreasing trisulfide bonds during recombinant production of polypeptides
|
EP3243836A1
(en)
|
2016-05-11 |
2017-11-15 |
F. Hoffmann-La Roche AG |
C-terminally fused tnf family ligand trimer-containing antigen binding molecules
|
CN109071640B
(zh)
|
2016-05-11 |
2022-10-18 |
豪夫迈·罗氏有限公司 |
经修饰抗生腱蛋白抗体及使用方法
|
CN109071652B
(zh)
|
2016-05-11 |
2022-09-23 |
豪夫迈·罗氏有限公司 |
包含tnf家族配体三聚体和生腱蛋白结合模块的抗原结合分子
|
HRP20221298T1
(hr)
|
2016-05-13 |
2022-12-23 |
Bioatla, Inc. |
Anti-ror2 protutijela, fragmenti protutijela, njihovi imunokonjugati i njihove uporabe
|
EP3243832A1
(en)
|
2016-05-13 |
2017-11-15 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and pd1 binding moiety
|
WO2017201036A1
(en)
|
2016-05-17 |
2017-11-23 |
Genentech, Inc. |
Stromal gene signatures for diagnosis and use in immunotherapy
|
CN109152843A
(zh)
|
2016-05-20 |
2019-01-04 |
豪夫迈·罗氏有限公司 |
Protac抗体缀合物及其使用方法
|
AU2017268460B2
(en)
|
2016-05-20 |
2023-12-14 |
Harpoon Therapeutics, Inc. |
Single domain serum albumin binding protein
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
CA3025306A1
(en)
|
2016-05-23 |
2017-11-30 |
Momenta Pharmaceuticals, Inc. |
Compositions and methods related to engineered fc constructs
|
JP7301540B2
(ja)
|
2016-05-26 |
2023-07-03 |
チールー ピュージェット サウンド バイオセラピューティクス コーポレイション |
抗体の混合物
|
EP3465221B1
(en)
|
2016-05-27 |
2020-07-22 |
H. Hoffnabb-La Roche Ag |
Bioanalytical method for the characterization of site-specific antibody-drug conjugates
|
WO2017210617A2
(en)
|
2016-06-02 |
2017-12-07 |
Porter, David, L. |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
TW201902512A
(zh)
|
2016-06-02 |
2019-01-16 |
瑞士商赫孚孟拉羅股份公司 |
治療方法
|
CN116458475A
(zh)
|
2016-06-03 |
2023-07-21 |
瑞泽恩制药公司 |
表达外源末端脱氧核苷酸转移酶的非人动物
|
US10639378B2
(en)
|
2016-06-06 |
2020-05-05 |
Genentech, Inc. |
Silvestrol antibody-drug conjugates and methods of use
|
US10787518B2
(en)
|
2016-06-14 |
2020-09-29 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
EP3472177B1
(en)
|
2016-06-17 |
2024-08-14 |
F. Hoffmann-La Roche AG |
Purification of multispecific antibodies
|
WO2017223405A1
(en)
|
2016-06-24 |
2017-12-28 |
Genentech, Inc. |
Anti-polyubiquitin multispecific antibodies
|
US20190233533A1
(en)
|
2016-06-28 |
2019-08-01 |
Umc Utrecht Holding B.V. |
Treatment Of IgE-Mediated Diseases With Antibodies That Specifically Bind CD38
|
KR20190020341A
(ko)
|
2016-06-28 |
2019-02-28 |
젠코어 인코포레이티드 |
소마토스타틴 수용체 2에 결합하는 이종이량체 항체
|
JP7175769B2
(ja)
|
2016-06-30 |
2022-11-21 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
改善された養子t細胞療法
|
CN109790526A
(zh)
|
2016-07-01 |
2019-05-21 |
分解治疗有限责任公司 |
优化的二核酸酶融合体和方法
|
EP3478717B1
(en)
|
2016-07-04 |
2022-01-05 |
F. Hoffmann-La Roche AG |
Novel antibody format
|
WO2018011691A1
(en)
|
2016-07-12 |
2018-01-18 |
Nestec S.A. |
Competitive immunoassay methods
|
KR102632202B1
(ko)
|
2016-07-14 |
2024-02-02 |
젠맵 에이/에스 |
Cd40 및 cd137에 대한 다중특이적 항체
|
WO2018013918A2
(en)
|
2016-07-15 |
2018-01-18 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
DK3496739T3
(da)
|
2016-07-15 |
2021-05-10 |
Acceleron Pharma Inc |
Sammensætninger omfattende actriia-polypeptider til brug i behandlingen af pulmonal hypertension
|
TWI790206B
(zh)
|
2016-07-18 |
2023-01-21 |
法商賽諾菲公司 |
特異性結合至cd3和cd123的雙特異性抗體樣結合蛋白
|
WO2018014260A1
(en)
|
2016-07-20 |
2018-01-25 |
Nanjing Legend Biotech Co., Ltd. |
Multispecific antigen binding proteins and methods of use thereof
|
EP3487867A2
(en)
|
2016-07-22 |
2019-05-29 |
Amgen Inc. |
Methods of purifying fc-containing proteins
|
MA45715A
(fr)
|
2016-07-25 |
2019-05-29 |
Biogen Ma Inc |
Anticorps anti-hspa5 (grp78) et leurs utilisations
|
CA3031909A1
(en)
|
2016-07-27 |
2018-02-01 |
Acceleron Pharma Inc. |
Methods and compositions for treating myelofibrosis
|
US11471488B2
(en)
|
2016-07-28 |
2022-10-18 |
Alpine Immune Sciences, Inc. |
CD155 variant immunomodulatory proteins and uses thereof
|
BR112019001570A2
(pt)
|
2016-07-28 |
2019-07-09 |
Novartis Ag |
terapias de combinação de receptores de antígeno quiméricos e inibidores de pd-1
|
CA3032120A1
(en)
|
2016-07-28 |
2018-02-01 |
Alpine Immune Sciences, Inc. |
Cd155 variant immunomodulatory proteins and uses thereof
|
US11834490B2
(en)
|
2016-07-28 |
2023-12-05 |
Alpine Immune Sciences, Inc. |
CD112 variant immunomodulatory proteins and uses thereof
|
CN117986372A
(zh)
|
2016-07-29 |
2024-05-07 |
中外制药株式会社 |
显示增加的备选fviii辅因子功能活性的双特异性抗体
|
JOP20170154B1
(ar)
|
2016-08-01 |
2023-03-28 |
Omeros Corp |
تركيبات وطرق لتثبيط masp-3 لعلاج أمراض واضطرابات مختلفة
|
CN110267677A
(zh)
|
2016-08-01 |
2019-09-20 |
诺华股份有限公司 |
使用与原m2巨噬细胞分子抑制剂组合的嵌合抗原受体治疗癌症
|
EP3494138A1
(en)
|
2016-08-02 |
2019-06-12 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
US11447542B2
(en)
|
2016-08-05 |
2022-09-20 |
Medimmune, Llc |
Anti-O2 antibodies and uses thereof
|
EP3494991A4
(en)
|
2016-08-05 |
2020-07-29 |
Chugai Seiyaku Kabushiki Kaisha |
COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATING TO IL-8
|
WO2018027204A1
(en)
|
2016-08-05 |
2018-02-08 |
Genentech, Inc. |
Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
|
WO2018029124A1
(en)
|
2016-08-08 |
2018-02-15 |
F. Hoffmann-La Roche Ag |
Therapeutic and diagnostic methods for cancer
|
WO2018030806A1
(ko)
|
2016-08-10 |
2018-02-15 |
아주대학교산학협력단 |
항체 중쇄불변부위 이종이중체에 융합된 사이토카인 및 이를 포함하는 약제학적 조성물
|
CN110267977A
(zh)
|
2016-08-10 |
2019-09-20 |
亚洲大学校产学协力团 |
细胞因子免疫球蛋白Fc融合异二聚体和包含其的药物组合物
|
CN109689111B
(zh)
|
2016-08-11 |
2024-04-05 |
基因泰克公司 |
吡咯并苯并二氮杂䓬前药及其抗体缀合物
|
CN109716127B
(zh)
|
2016-08-15 |
2022-06-14 |
豪夫迈·罗氏有限公司 |
定量包含非离子表面活性剂和多肽的组合物中非离子表面活性剂的层析方法
|
CA3034057A1
(en)
|
2016-08-22 |
2018-03-01 |
CHO Pharma Inc. |
Antibodies, binding fragments, and methods of use
|
WO2018038046A1
(ja)
|
2016-08-22 |
2018-03-01 |
中外製薬株式会社 |
ヒトgpc3ポリペプチドを発現する遺伝子改変非ヒト動物
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
WO2018045110A1
(en)
|
2016-08-30 |
2018-03-08 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
CA3035081A1
(en)
|
2016-09-02 |
2018-03-08 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of treating b cell disorders
|
KR101928981B1
(ko)
|
2016-09-02 |
2018-12-13 |
고려대학교 산학협력단 |
항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 IL-21 (heterodimeric Fc-fused IL-21) 및 이를 포함하는 약제학적 조성물
|
WO2018049261A1
(en)
|
2016-09-09 |
2018-03-15 |
Icellhealth Consulting Llc |
Oncolytic virus expressing immune checkpoint modulators
|
RS65595B1
(sr)
|
2016-09-14 |
2024-06-28 |
Teneoone Inc |
Antitela koja vezuju cd3
|
SG10201607778XA
(en)
|
2016-09-16 |
2018-04-27 |
Chugai Pharmaceutical Co Ltd |
Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
|
EP3515932B1
(en)
|
2016-09-19 |
2023-11-22 |
F. Hoffmann-La Roche AG |
Complement factor based affinity chromatography
|
JOP20190009A1
(ar)
|
2016-09-21 |
2019-01-27 |
Alx Oncology Inc |
أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
|
MX2019003225A
(es)
|
2016-09-21 |
2019-06-10 |
Aptevo Res & Development Llc |
Proteínas de unión a cd123 y composiciones y métodos relacionados.
|
CN110023339A
(zh)
|
2016-09-23 |
2019-07-16 |
Csl有限公司 |
凝血因子结合蛋白及其应用
|
RU2752785C2
(ru)
|
2016-09-23 |
2021-08-04 |
Дженентек, Инк. |
Применение антагонистов il-13 для лечения атопического дерматита
|
EP3504234A4
(en)
*
|
2016-09-29 |
2020-12-02 |
Beijing Hanmi Pharmaceutical Co., Ltd. |
HETERODIMER IMMUNOGLOBULIN CONSTRUCTS AND MANUFACTURING PROCESSES
|
JP6785372B2
(ja)
|
2016-09-30 |
2020-11-18 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
多重特異性分子の機能分析のためのsprに基づく二重結合アッセイ
|
KR20240046648A
(ko)
|
2016-09-30 |
2024-04-09 |
얀센 바이오테크 인코포레이티드 |
항-il23 특이적 항체로 건선을 치료하는 안전하고 효과적인 방법
|
WO2018060301A1
(en)
|
2016-09-30 |
2018-04-05 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies against cd3
|
JP2019529509A
(ja)
|
2016-10-05 |
2019-10-17 |
アクセレロン ファーマ インコーポレーテッド |
腎臓疾患を治療するための組成物および方法
|
BR112019006993A2
(pt)
|
2016-10-05 |
2019-09-03 |
Acceleron Pharma Inc |
heteromultímeros de alk4:actriib e usos dos mesmos
|
CN110036025B
(zh)
|
2016-10-05 |
2024-03-22 |
阿塞勒隆制药公司 |
变体ActRIIB蛋白及其用途
|
EP3522933B1
(en)
|
2016-10-05 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Methods for preparing antibody drug conjugates
|
KR20190072528A
(ko)
|
2016-10-06 |
2019-06-25 |
제넨테크, 인크. |
암에 대한 치료 및 진단 방법
|
TW202340473A
(zh)
|
2016-10-07 |
2023-10-16 |
瑞士商諾華公司 |
利用嵌合抗原受體之癌症治療
|
WO2018067993A1
(en)
|
2016-10-07 |
2018-04-12 |
TCR2 Therapeutics Inc. |
Compositions and methods for t-cell receptors reprogramming using fusion proteins
|
WO2018068201A1
(en)
|
2016-10-11 |
2018-04-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against ctla-4
|
AU2017342560B2
(en)
|
2016-10-14 |
2022-03-17 |
Xencor, Inc. |
IL15/IL15Ralpha heterodimeric Fc-fusion proteins
|
AU2017346488A1
(en)
|
2016-10-19 |
2019-05-30 |
Humabs Biomed Sa |
Anti-O1 antibodies and uses thereof
|
US11965884B2
(en)
|
2016-10-19 |
2024-04-23 |
Alexion Pharmaceuticals, Inc. |
Method of quantitating unbound C5 in a sample
|
JP7173965B2
(ja)
|
2016-10-19 |
2022-11-16 |
アレクシオン ファーマシューティカルズ, インコーポレイテッド |
試料中の非結合C5aの定量化方法
|
WO2018075692A2
(en)
|
2016-10-19 |
2018-04-26 |
Invenra Inc. |
Antibody constructs
|
CN110267678A
(zh)
|
2016-10-29 |
2019-09-20 |
霍夫曼-拉罗奇有限公司 |
抗mic抗体和使用方法
|
CN110167964B
(zh)
|
2016-11-02 |
2023-12-01 |
百时美施贵宝公司 |
组合用于治疗多发性骨髓瘤的针对bcma和cd3的双特异性抗体和免疫药物
|
EP3535299A1
(en)
|
2016-11-04 |
2019-09-11 |
Novimmune S.A. |
Anti-cd19 antibodies and methods of use thereof
|
WO2018144097A1
(en)
|
2016-11-04 |
2018-08-09 |
Akeagen Llc |
Genetically modified non-human animals and methods for producing heavy chain-only antibodies
|
JP2019534044A
(ja)
|
2016-11-08 |
2019-11-28 |
クイル ピュージェット サウンド バイオセラピューティクス コーポレーション |
抗pd1および抗ctla4抗体
|
WO2018089702A1
(en)
|
2016-11-10 |
2018-05-17 |
Keros Therapeutics, Inc. |
Gdnf fusion polypeptides and methods of use thereof
|
EP3538555A1
(en)
|
2016-11-14 |
2019-09-18 |
Amgen Inc. |
Bispecific or biparatopic antigen binding proteins and uses thereof
|
US11466094B2
(en)
|
2016-11-15 |
2022-10-11 |
Genentech, Inc. |
Dosing for treatment with anti-CD20/anti-CD3 bispecific antibodies
|
KR20240065333A
(ko)
|
2016-11-16 |
2024-05-14 |
얀센 바이오테크 인코포레이티드 |
항-il23 특이적 항체로 건선을 치료하는 방법
|
BR112019010051A2
(pt)
*
|
2016-11-18 |
2019-09-03 |
Beijing Hanmi Pharmaceutical Co Ltd |
anticorpo biespecífico heterodimérico, polinucleotídeo isolado, vetor de expressão recombinante, célula hospedeira, composição, método de produzir o anticorpo biespecífico heterodimérico, uso do anticorpo bieífico heterodimérico, e método de prevenir e/ou tratar uma doença
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
WO2018094275A1
(en)
|
2016-11-18 |
2018-05-24 |
Tolero Pharmaceuticals, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
JOP20190100A1
(ar)
|
2016-11-19 |
2019-05-01 |
Potenza Therapeutics Inc |
بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامها
|
JP7291396B2
(ja)
|
2016-11-22 |
2023-06-15 |
ティーシーアール2 セラピューティクス インク. |
融合タンパク質を用いたtcrの再プログラミングのための組成物及び方法
|
JP7215997B2
(ja)
|
2016-11-23 |
2023-01-31 |
ハープーン セラピューティクス,インク. |
前立腺特異的膜抗原(psma)を標的とする三重特異性タンパク質と使用方法
|
US20230192896A1
(en)
|
2016-11-23 |
2023-06-22 |
Bioverativ Therapeutics Inc. |
Bispecific antibodies binding to coagulation factor ix and coagulation factor x
|
CA3044659A1
(en)
|
2016-11-23 |
2018-05-31 |
Harpoon Therapeutics, Inc. |
Prostate specific membrane antigen binding protein
|
CA3045323A1
(en)
|
2016-12-02 |
2018-06-07 |
Juno Therapeutics, Inc. |
Engineered b cells and related compositions and methods
|
TW202328181A
(zh)
|
2016-12-07 |
2023-07-16 |
美商建南德克公司 |
抗-tau抗體及使用方法
|
CA3045294A1
(en)
|
2016-12-07 |
2018-06-14 |
Genentech, Inc. |
Anti-tau antibodies and methods of use
|
US20180206726A1
(en)
|
2016-12-07 |
2018-07-26 |
Progenity Inc. |
Gastrointestinal tract detection methods, devices and systems
|
MA50948A
(fr)
|
2016-12-07 |
2020-10-14 |
Agenus Inc |
Anticorps et procédés d'utilisation de ceux-ci
|
KR20190094222A
(ko)
*
|
2016-12-13 |
2019-08-12 |
데리니아, 인크. |
다가 조절성 t 세포 조절제
|
JP7141407B2
(ja)
|
2016-12-13 |
2022-09-22 |
エフ.ホフマン-ラ ロシュ アーゲー |
腫瘍試料における標的抗原の存在を決定する方法
|
WO2018112223A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a tlr modulator
|
WO2018112264A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor
|
EP3554343A1
(en)
|
2016-12-14 |
2019-10-23 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with an il-1 inhibitor
|
CA3045475A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor released using an ingestible device
|
MX2019006821A
(es)
|
2016-12-14 |
2019-10-21 |
Progenity Inc |
Tratamiento de una enfermedad del tracto gastrointestinal con un inhibidor de cinasa de janus (jak) y dispositivos.
|
JP7150723B2
(ja)
|
2016-12-14 |
2022-10-11 |
ビオラ・セラピューティクス・インコーポレイテッド |
消化管疾病のインテグリン阻害薬による治療
|
CN110430801B
(zh)
|
2016-12-14 |
2024-04-30 |
比奥拉治疗股份有限公司 |
使用tnf抑制剂治疗胃肠道疾病
|
CA3046023A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with an immunosuppressant
|
WO2018112235A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a smad7 inhibitor
|
WO2018112237A1
(en)
|
2016-12-14 |
2018-06-21 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor
|
WO2018111340A1
(en)
|
2016-12-16 |
2018-06-21 |
Novartis Ag |
Methods for determining potency and proliferative function of chimeric antigen receptor (car)-t cells
|
KR20190099260A
(ko)
|
2016-12-19 |
2019-08-26 |
톨레로 파마수티컬스, 인크. |
프로파일링 펩티드 및 감도 프로파일링을 위한 방법
|
WO2018118780A1
(en)
|
2016-12-19 |
2018-06-28 |
Calico Biolabs, Inc. |
Monovalent and divalent binding proteins
|
TWI829628B
(zh)
|
2016-12-19 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
與靶向4-1bb (cd137)促效劑併用之組合療法
|
AU2017384126A1
(en)
|
2016-12-20 |
2019-05-02 |
F. Hoffmann-La Roche Ag |
Combination therapy of anti-CD20/anti-CD3 bispecific antibodies and 4-1BB (CD137) agonists
|
EP3559249A1
(en)
|
2016-12-21 |
2019-10-30 |
H. Hoffnabb-La Roche Ag |
Method for in vitro glycoengineering of antibodies
|
JP7215999B2
(ja)
|
2016-12-21 |
2023-01-31 |
エフ.ホフマン-ラ ロシュ アーゲー |
抗体またはリガンドの結合および機能を決定するためのアッセイ法
|
JP6931058B2
(ja)
|
2016-12-21 |
2021-09-01 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
抗体のインビトロ糖鎖工学における酵素の再使用
|
US11434299B2
(en)
|
2016-12-21 |
2022-09-06 |
Teneobio, Inc. |
Anti-BCMA heavy chain-only antibodies
|
MX2019006266A
(es)
|
2016-12-21 |
2019-08-21 |
Hoffmann La Roche |
Glucomanipulacion in vitro de anticuerpos.
|
EP3360898A1
(en)
|
2017-02-14 |
2018-08-15 |
Boehringer Ingelheim International GmbH |
Bispecific anti-tnf-related apoptosis-inducing ligand receptor 2 and anti-cadherin 17 binding molecules for the treatment of cancer
|
WO2018122053A1
(en)
|
2016-12-29 |
2018-07-05 |
F. Hoffmann-La Roche Ag |
Anti-angiopoietin-2 antibody formulation
|
CR20190309A
(es)
|
2017-01-03 |
2019-08-21 |
Hoffmann La Roche |
Moleculas de unión de3 antígeno biespecíficas que comprenden el clon 20h4.9 anti-4-1bb
|
TW201825515A
(zh)
|
2017-01-04 |
2018-07-16 |
美商伊繆諾金公司 |
Met抗體以及其免疫結合物及用途
|
US11299530B2
(en)
|
2017-01-05 |
2022-04-12 |
Kahr Medical Ltd. |
SIRP alpha-CD70 fusion protein and methods of use thereof
|
WO2018127916A1
(en)
|
2017-01-05 |
2018-07-12 |
Kahr Medical Ltd. |
A pd1-cd70 fusion protein and methods of use thereof
|
RU2769513C2
(ru)
|
2017-01-05 |
2022-04-01 |
Кахр Медикал Лтд. |
Слитый белок pd1-4-1bbl и способы его применения
|
DK3565828T3
(da)
|
2017-01-05 |
2022-02-21 |
Kahr Medical Ltd |
Sirp1 alpha-41bbl-fusionsprotein og fremgangsmåder til anvendelse deraf
|
JP7069476B2
(ja)
|
2017-01-06 |
2022-05-18 |
博奥信生物技▲術▼(南京)有限公司 |
ErbB2抗体およびその使用
|
BR112019013955A2
(pt)
|
2017-01-06 |
2020-02-11 |
Momenta Pharmaceuticals, Inc. |
Composições e métodos relacionados a construtos de fc manipulados
|
WO2018129522A1
(en)
|
2017-01-09 |
2018-07-12 |
Torch Therapeutics |
Conditionally effective bispecific therapeutics
|
EP3568468A4
(en)
|
2017-01-12 |
2020-12-30 |
Eureka Therapeutics, Inc. |
RECOMBINATION PRODUCTS TARGETING PEPTIDE HISTONE H3 / MHC COMPLEXES AND THEIR USES
|
ES2912408T3
(es)
|
2017-01-26 |
2022-05-25 |
Novartis Ag |
Composiciones de CD28 y métodos para terapia con receptores quiméricos para antígenos
|
EP3573658A4
(en)
|
2017-01-30 |
2021-07-21 |
Janssen Biotech, Inc. |
ANTI-TNF ANTIBODIES, COMPOSITIONS, AND METHODS FOR TREATMENT OF ACTIVE PSORIATIC ARTHRITIS
|
JP2020506700A
(ja)
|
2017-01-31 |
2020-03-05 |
ノバルティス アーゲー |
多重特異性を有するキメラt細胞受容体タンパク質を用いた癌の治療
|
WO2018144784A1
(en)
|
2017-02-01 |
2018-08-09 |
Smet Pharmaceutical Inc. |
MONOMERIC HUMAN IgG1 Fc AND BISPECIFIC ANTIBODIES
|
MX2019009377A
(es)
|
2017-02-07 |
2019-12-11 |
Janssen Biotech Inc |
Anticuerpos anti-tnf, composiciones y metodos para el tratamiento de la espondilitis anquilosante activa.
|
RU2019128134A
(ru)
|
2017-02-07 |
2021-03-09 |
Дайити Санкио Компани, Лимитед |
Антитело против gprc5d и молекула, содержащая антитело
|
US11266745B2
(en)
|
2017-02-08 |
2022-03-08 |
Imaginab, Inc. |
Extension sequences for diabodies
|
AU2018219887B2
(en)
|
2017-02-08 |
2024-08-15 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
|
US10738131B2
(en)
|
2017-02-10 |
2020-08-11 |
Genentech, Inc. |
Anti-tryptase antibodies, compositions thereof, and uses thereof
|
US20200291089A1
(en)
|
2017-02-16 |
2020-09-17 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
US10626169B2
(en)
|
2017-02-17 |
2020-04-21 |
Sanofi |
Multispecific binding molecules having specificity to dystroglycan and laminin-2
|
KR20240049621A
(ko)
|
2017-02-17 |
2024-04-16 |
사노피 |
디스트로글리칸 및 라미닌-2에 대한 특이성을 갖는 다중특이적 결합 분자
|
WO2018152496A1
(en)
|
2017-02-17 |
2018-08-23 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Compositions and methods for the diagnosis and treatment of zika virus infection
|
IL268660B2
(en)
|
2017-02-17 |
2024-03-01 |
Denali Therapeutics Inc |
Polypeptides that bind to a transgenic transferrin receptor, polynucleotides encoding them, methods for their preparation and use
|
CA3235295A1
(en)
|
2017-02-20 |
2018-08-23 |
Dragonfly Therapeutics, Inc. |
Proteins binding her2, nkg2d and cd16
|
EP3586872A4
(en)
|
2017-02-24 |
2020-12-30 |
Chugai Seiyaku Kabushiki Kaisha |
PHARMACEUTICAL COMPOSITION, ANTIG-BINDING MOLECULES, TREATMENT METHODS AND SCREENING METHODS
|
EP3589662A4
(en)
|
2017-02-28 |
2020-12-30 |
Harpoon Therapeutics, Inc. |
INDUCTIBLE MONOVALENT ANTIGBINDING PROTEIN
|
WO2018160841A1
(en)
|
2017-03-01 |
2018-09-07 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
CN118063619A
(zh)
|
2017-03-02 |
2024-05-24 |
诺华股份有限公司 |
工程化的异源二聚体蛋白质
|
CN116836285A
(zh)
|
2017-03-09 |
2023-10-03 |
健玛保 |
针对pd-l1的抗体
|
CA3052357A1
(en)
|
2017-03-10 |
2018-09-13 |
F. Hoffmann-La Roche Ag |
Method for producing multispecific antibodies
|
EP4306537A3
(en)
|
2017-03-16 |
2024-03-06 |
Alpine Immune Sciences, Inc. |
Pd-l1 variant immunomodulatory proteins and uses thereof
|
EP3596114A2
(en)
|
2017-03-16 |
2020-01-22 |
Alpine Immune Sciences, Inc. |
Cd80 variant immunomodulatory proteins and uses thereof
|
US11732022B2
(en)
|
2017-03-16 |
2023-08-22 |
Alpine Immune Sciences, Inc. |
PD-L2 variant immunomodulatory proteins and uses thereof
|
CN110891611B
(zh)
|
2017-03-22 |
2024-03-29 |
阿森迪斯制药公司 |
水凝胶交联透明质酸前药组合物和方法
|
AR111249A1
(es)
|
2017-03-22 |
2019-06-19 |
Genentech Inc |
Composiciones de anticuerpo optimizadas para el tratamiento de trastornos oculares
|
KR20190133005A
(ko)
|
2017-03-24 |
2019-11-29 |
젠야쿠코교가부시키가이샤 |
항 IgM/B 세포 표면 항원 이중 특이성 항체
|
CN111094355A
(zh)
|
2017-03-27 |
2020-05-01 |
拜奥穆尼克斯制药 |
稳定的多特异性抗体
|
EP3601351A1
(en)
|
2017-03-27 |
2020-02-05 |
Celgene Corporation |
Methods and compositions for reduction of immunogenicity
|
MA48996A
(fr)
|
2017-03-28 |
2020-02-05 |
Genentech Inc |
Méthodes de traitement de maladies neurodégénératives
|
WO2018178074A1
(en)
|
2017-03-29 |
2018-10-04 |
F. Hoffmann-La Roche Ag |
Trimeric antigen binding molecules specific for a costimulatory tnf receptor
|
JP7205995B2
(ja)
|
2017-03-29 |
2023-01-17 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
共刺激性tnf受容体に対する二重特異性抗原結合分子
|
JP7196094B2
(ja)
|
2017-03-29 |
2022-12-26 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
共刺激tnf受容体のための二重特異性抗原結合分子
|
WO2018183932A1
(en)
|
2017-03-30 |
2018-10-04 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor
|
EP3600414A1
(en)
|
2017-03-30 |
2020-02-05 |
Progenity Inc. |
Treatment of a disease of the gastrointestinal tract with il-10 or an il-10 agonist
|
JP2020515579A
(ja)
|
2017-03-30 |
2020-05-28 |
プロジェニティ, インコーポレイテッド |
消化管疾病の生菌生物学的製剤による治療
|
US20200094031A1
(en)
|
2017-03-30 |
2020-03-26 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with a chst15 inhibitor
|
US20210138213A1
(en)
|
2017-03-30 |
2021-05-13 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
|
MX2019011660A
(es)
|
2017-03-31 |
2019-11-18 |
Merus Nv |
Anticuerpos biespecificos que se unen al receptor 2 del factor de crecimiento humano (erbb-2) y receptor 3 del factor de crecimiento humano (erbb3) para usarse en el tratamiento de celulas que tienen un gen de fusion de neuregulina-1 (nrg1).
|
US20200270359A1
(en)
|
2017-03-31 |
2020-08-27 |
Genmab Holding B.V. |
Bispecific anti-cd37 antibodies, monoclonal anti-cd37 antibodies and methods of use thereof
|
SG11201909156RA
(en)
|
2017-04-01 |
2019-10-30 |
Beijing hanmi pharm co ltd |
Anti-pd-l1/anti-pd-1 natural antibody structure-like heterodimeric bispecific antibody and preparation thereof
|
SG11201909218RA
(en)
|
2017-04-03 |
2019-11-28 |
Hoffmann La Roche |
Antibodies binding to steap-1
|
ES2928718T3
(es)
|
2017-04-03 |
2022-11-22 |
Hoffmann La Roche |
Inmunoconjugados de un anticuerpo anti-PD-1 con una IL-2 mutante o con IL-15
|
JP7148539B2
(ja)
|
2017-04-03 |
2022-10-05 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
免疫抱合体
|
WO2018187227A1
(en)
|
2017-04-03 |
2018-10-11 |
Concologie, Inc. |
Methods for treating cancer using ps-targeting antibodies with immuno-oncology agents
|
CN110402255B
(zh)
|
2017-04-04 |
2022-12-02 |
豪夫迈·罗氏有限公司 |
新颖的能够特异性结合cd40和fap的双特异性抗原结合分子
|
KR102408873B1
(ko)
|
2017-04-05 |
2022-06-15 |
에프. 호프만-라 로슈 아게 |
Pd1 및 lag3에 특이적으로 결합하는 이중특이적 항체
|
DK3606954T3
(en)
|
2017-04-05 |
2022-09-26 |
Hoffmann La Roche |
Anti-LAG3-antistoffer
|
MX2019012198A
(es)
|
2017-04-11 |
2020-01-21 |
Inhibrx Inc |
Constructos de polipéptidos multiespecíficos que tienen unión limitada a cd3 y métodos de utilización de los mismos.
|
AU2018250875A1
(en)
|
2017-04-13 |
2019-10-03 |
F. Hoffmann-La Roche Ag |
An interleukin-2 immunoconjugate, a CD40 agonist, and optionally a PD-1 axis binding antagonist for use in methods of treating cancer
|
RU2665790C1
(ru)
|
2017-04-17 |
2018-09-04 |
Закрытое Акционерное Общество "Биокад" |
Моноклональное антитело к pd-l1
|
JOP20190248A1
(ar)
|
2017-04-21 |
2019-10-20 |
Amgen Inc |
بروتينات ربط مولد ضد trem2 واستخداماته
|
BR112019021812A2
(pt)
|
2017-04-21 |
2020-05-26 |
Kindred Biosciences, Inc. |
Molécula receptora de il4/il13 para uso veterinário
|
MA49131A
(fr)
|
2017-04-21 |
2020-03-25 |
Hoffmann La Roche |
Utilisation d'antagonistes de klk5 pour le traitement d'une maladie
|
EP4230649A3
(en)
|
2017-04-25 |
2023-10-25 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis and treatment of epstein barr virus infection
|
SG11201909728XA
(en)
|
2017-04-26 |
2019-11-28 |
Eureka Therapeutics Inc |
Constructs specifically recognizing glypican 3 and uses thereof
|
US20200055948A1
(en)
|
2017-04-28 |
2020-02-20 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
WO2018201051A1
(en)
|
2017-04-28 |
2018-11-01 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
EP3615678B1
(en)
|
2017-04-28 |
2024-07-31 |
F. Hoffmann-La Roche AG |
Antibody selection method
|
US11851486B2
(en)
|
2017-05-02 |
2023-12-26 |
National Center Of Neurology And Psychiatry |
Method for predicting and evaluating therapeutic effect in diseases related to IL-6 and neutrophils
|
KR20200026810A
(ko)
|
2017-05-12 |
2020-03-11 |
하푼 테라퓨틱스, 인크. |
Msln 표적화 삼중 특이적 단백질 및 사용 방법
|
JOP20190256A1
(ar)
|
2017-05-12 |
2019-10-28 |
Icahn School Med Mount Sinai |
فيروسات داء نيوكاسل واستخداماتها
|
JP7090347B2
(ja)
|
2017-05-12 |
2022-06-24 |
ハープーン セラピューティクス,インク. |
メソテリン結合タンパク質
|
US11359014B2
(en)
|
2017-05-16 |
2022-06-14 |
Alector Llc |
Anti-siglec-5 antibodies and methods of use thereof
|
CN110753703B
(zh)
|
2017-05-23 |
2024-04-09 |
德国亥姆霍兹慕尼黑中心健康与环境研究中心(有限公司) |
新的cd73抗体、其制备和用途
|
AR111963A1
(es)
|
2017-05-26 |
2019-09-04 |
Univ California |
Método y moléculas
|
WO2018215835A1
(en)
|
2017-05-26 |
2018-11-29 |
Novimmune Sa |
Anti-cd47 x anti-mesothelin antibodies and methods of use thereof
|
US20210246227A1
(en)
|
2017-05-31 |
2021-08-12 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
EP3409322A1
(en)
|
2017-06-01 |
2018-12-05 |
F. Hoffmann-La Roche AG |
Treatment method
|
EP3634994A4
(en)
|
2017-06-05 |
2021-06-30 |
Janssen Biotech, Inc. |
SURFACE LOAD ENGINEERING PROCESSES FOR THE PRODUCTION OF A BISPECIFIC ANTIBODY
|
AU2018281280A1
(en)
|
2017-06-07 |
2020-01-16 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for internalizing enzymes
|
UY37758A
(es)
|
2017-06-12 |
2019-01-31 |
Novartis Ag |
Método de fabricación de anticuerpos biespecíficos, anticuerpos biespecíficos y uso terapéutico de dichos anticuerpos
|
WO2018232020A1
(en)
|
2017-06-13 |
2018-12-20 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
US20190062428A1
(en)
|
2017-06-19 |
2019-02-28 |
Surface Oncology, Inc. |
Combination of anti-cd47 antibodies and cell death-inducing agents, and uses thereof
|
WO2018237006A1
(en)
|
2017-06-20 |
2018-12-27 |
Teneoone, Inc. |
ANTIBODIES ONLY TO HEAVY ANTI-BCMA CHAINS
|
WO2018237037A2
(en)
|
2017-06-20 |
2018-12-27 |
Teneobio, Inc. |
HEAVY CHAIN ANTIBODY ONLY ANTI-BCMA
|
WO2018237148A1
(en)
|
2017-06-21 |
2018-12-27 |
Gilead Sciences, Inc. |
MULTISPECIFIC ANTIBODIES TARGETING HIV GP120 AND CD3
|
JP7433910B2
(ja)
|
2017-06-22 |
2024-02-20 |
ノバルティス アーゲー |
Cd73に対する抗体分子及びその使用
|
GB201709970D0
(en)
|
2017-06-22 |
2017-08-09 |
Kymab Ltd |
Bispecific antigen-binding molecules
|
WO2019006007A1
(en)
|
2017-06-27 |
2019-01-03 |
Novartis Ag |
POSOLOGICAL REGIMES FOR ANTI-TIM3 ANTIBODIES AND USES THEREOF
|
JP2020529832A
(ja)
|
2017-06-30 |
2020-10-15 |
ゼンコア インコーポレイテッド |
IL−15/IL−15Rαおよび抗原結合ドメインを含む標的化ヘテロダイマーFc融合タンパク質
|
JP7245793B2
(ja)
|
2017-06-30 |
2023-03-24 |
ザイムワークス ビーシー インコーポレイテッド |
安定化したキメラFab
|
GB201710984D0
(en)
|
2017-07-07 |
2017-08-23 |
Kymab Ltd |
Cells, vertebrates, populations & methods
|
AR112603A1
(es)
|
2017-07-10 |
2019-11-20 |
Lilly Co Eli |
Anticuerpos biespecíficos inhibidores de punto de control
|
MY202336A
(en)
|
2017-07-11 |
2024-04-24 |
Compass Therapeutics Llc |
Agonist antibodies that bind human cd137 and uses thereof
|
CN111316099A
(zh)
|
2017-07-12 |
2020-06-19 |
约翰霍普金斯大学 |
用于1型糖尿病诊断的基于脂蛋白体的znt8自身抗原
|
WO2019018629A1
(en)
|
2017-07-19 |
2019-01-24 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
ANTIBODIES AND METHODS FOR DIAGNOSING AND TREATING INFECTION WITH HEPATITIS B VIRUS
|
EP3655023A1
(en)
|
2017-07-20 |
2020-05-27 |
Novartis AG |
Dosage regimens of anti-lag-3 antibodies and uses thereof
|
JP2020527351A
(ja)
|
2017-07-21 |
2020-09-10 |
ジェネンテック, インコーポレイテッド |
がんの治療法及び診断法
|
PL3658589T3
(pl)
|
2017-07-26 |
2024-03-18 |
Forty Seven, Inc. |
Przeciwciała anty-sirp-alfa i powiązane sposoby
|
WO2019020745A1
(en)
|
2017-07-28 |
2019-01-31 |
F. Hoffmann-La Roche Ag |
BISPECIFIC ANTIBODY FORMULATION
|
CN111182951A
(zh)
|
2017-08-01 |
2020-05-19 |
指南针制药有限责任公司 |
过滤和层析荚以及使用其的方法
|
KR20200041897A
(ko)
|
2017-08-01 |
2020-04-22 |
에이비 스튜디오 인코포레이티드 |
이중특이 항체 및 그의 용도
|
WO2019028283A1
(en)
|
2017-08-03 |
2019-02-07 |
Alector Llc |
ANTI-CD33 ANTIBODIES AND METHODS OF USE
|
CR20230170A
(es)
|
2017-08-03 |
2023-05-31 |
Alector Llc |
ANTICUERPOS ANTI-TREM2 Y MÉTODOS PARA UTILIZARLOS (divisional 2019-0485)
|
CA3071211A1
(en)
|
2017-08-04 |
2019-02-07 |
Genmab A/S |
Binding agents binding to pd-l1 and cd137 and use thereof
|
MA49846A
(fr)
|
2017-08-09 |
2020-06-17 |
Merus Nv |
Anticorps qui se lient à l'egfr et à cmet
|
CN111295394B
(zh)
|
2017-08-11 |
2024-06-11 |
豪夫迈·罗氏有限公司 |
抗cd8抗体及其用途
|
US20200306516A1
(en)
|
2017-08-14 |
2020-10-01 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with glatiramer or a pharmaceutically acceptable salt thereof
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
US11485781B2
(en)
|
2017-08-17 |
2022-11-01 |
Massachusetts Institute Of Technology |
Multiple specificity binders of CXC chemokines
|
CN111566262A
(zh)
|
2017-08-21 |
2020-08-21 |
天演药业公司 |
动态人抗体轻链文库
|
IL272696B1
(en)
|
2017-08-21 |
2024-09-01 |
Adagene Inc |
Dynamic human heavy chain antibody libraries
|
KR20200039778A
(ko)
|
2017-08-22 |
2020-04-16 |
사나바이오, 엘엘씨 |
가용성 인터페론 수용체 및 그의 용도
|
KR20200047687A
(ko)
|
2017-09-08 |
2020-05-07 |
매버릭 테라퓨틱스, 인크. |
제약된 조건적으로 활성화된 결합 단백질
|
CN111315773A
(zh)
|
2017-09-08 |
2020-06-19 |
马弗里克治疗公司 |
含有Fc区的条件性活化的结合部分
|
WO2019055579A1
(en)
|
2017-09-12 |
2019-03-21 |
Tolero Pharmaceuticals, Inc. |
TREATMENT REGIME FOR CANCERS THAT ARE INSENSITIVE TO BCL-2 INHIBITORS USING THE MCL-1 ALVOCIDIB INHIBITOR
|
EP3457139A1
(en)
|
2017-09-19 |
2019-03-20 |
Promise Advanced Proteomics |
Antibody-like peptides for quantifying therapeutic antibodies
|
CN111094356B
(zh)
|
2017-09-25 |
2022-11-01 |
苏州丁孚靶点生物技术有限公司 |
一种蛋白质异二聚体及其用途
|
WO2019067499A1
(en)
|
2017-09-27 |
2019-04-04 |
Alexion Pharmaceuticals, Inc. |
BIOMARKER SIGNATURE FOR PREDICTING A TUMOR RESPONSE TO ANTI-CD200 THERAPY
|
SG11201810270SA
(en)
|
2017-09-29 |
2019-04-29 |
Chugai Pharmaceutical Co Ltd |
Multispecific antigen-binding molecules having blood coagulation factor viii (fviii) cofactor function-substituting activity and pharmaceutical formulations containing such a molecule as an active ing
|
RU2698048C2
(ru)
|
2017-10-03 |
2019-08-21 |
Закрытое Акционерное Общество "Биокад" |
МОНОКЛОНАЛЬНОЕ АНТИТЕЛО К IL-5Rα
|
EA039662B1
(ru)
|
2017-10-03 |
2022-02-24 |
Закрытое Акционерное Общество "Биокад" |
Антитела, специфичные к cd47 и pd-l1
|
KR20230020022A
(ko)
|
2017-10-10 |
2023-02-09 |
알파인 이뮨 사이언시즈, 인코포레이티드 |
Ctla-4 변이체 면역조절 단백질 및 이의 용도
|
CA3078800A1
(en)
|
2017-10-10 |
2019-04-18 |
Sanofi |
Anti-cd38 antibodies and methods of use
|
AU2018347521A1
(en)
|
2017-10-12 |
2020-05-07 |
Immunowake Inc. |
VEGFR-antibody light chain fusion protein
|
WO2019073069A1
(en)
|
2017-10-13 |
2019-04-18 |
Boehringer Ingelheim International Gmbh |
HUMAN ANTIBODIES AGAINST THOMSEN-NEW ANTIGEN (TN)
|
SG11202003359UA
(en)
|
2017-10-13 |
2020-05-28 |
Harpoon Therapeutics Inc |
Trispecific proteins and methods of use
|
EA202090739A1
(ru)
|
2017-10-13 |
2020-09-07 |
Харпун Терапьютикс, Инк. |
Белки, связывающие антиген созревания в-клеток
|
AR123115A1
(es)
|
2017-10-18 |
2022-11-02 |
Novartis Ag |
Composiciones y métodos para la degradación selectiva de proteínas
|
CA3072634A1
(en)
|
2017-10-18 |
2019-04-25 |
Sabine Rauth |
Human serum albumin variants and uses thereof
|
WO2019079520A2
(en)
|
2017-10-18 |
2019-04-25 |
Alpine Immune Sciences, Inc. |
ICOS VARIANT LIGAND IMMUNOMODULATORY IMMUNOMODULATORY PROTEINS, COMPOSITIONS AND METHODS THEREOF
|
CN111246885B
(zh)
|
2017-10-20 |
2024-06-11 |
豪夫迈·罗氏有限公司 |
从单特异性抗体生成多特异性抗体的方法
|
SG11202003177RA
(en)
|
2017-10-25 |
2020-05-28 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
MX2020004100A
(es)
|
2017-10-30 |
2020-07-24 |
Hoffmann La Roche |
Metodo para generacion in vivo de anticuerpos multiespecificos a partir de anticuerpos monoespecificos.
|
US11718679B2
(en)
|
2017-10-31 |
2023-08-08 |
Compass Therapeutics Llc |
CD137 antibodies and PD-1 antagonists and uses thereof
|
EP3704150A1
(en)
|
2017-11-01 |
2020-09-09 |
F. Hoffmann-La Roche AG |
The compbody - a multivalent target binder
|
WO2019086499A1
(en)
|
2017-11-01 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
Novel tnf family ligand trimer-containing antigen binding molecules
|
US11339221B2
(en)
|
2017-11-01 |
2022-05-24 |
Tufts Medical Center, Inc. |
Bispecific antibody constructs and methods of use
|
BR112020008031A2
(pt)
|
2017-11-01 |
2020-10-27 |
F. Hoffmann-La Roche Ag |
anticorpo multiespecíficos, método para a preparação do anticorpo multiespecífico, conjunto de ácidos nucleicos, vetor de expressão, célula hospedeira e composição farmacêutica
|
BR112020007630A2
(pt)
|
2017-11-01 |
2020-11-17 |
F. Hoffmann-La Roche Ag |
anticorpo biespecífico ox40, produto farmacêutico, composição farmacêutica e anticorpos biespecíficos anti-fap/ anti-ox40
|
US20210324108A1
(en)
|
2017-11-01 |
2021-10-21 |
Hoffmann-La Roche Inc. |
Bispecific 2+1 contorsbodies
|
RU2020117439A
(ru)
|
2017-11-02 |
2021-12-02 |
Байер Акциенгезельшафт |
БИСПЕЦИФИЧЕСКИЕ АНТИТЕЛА, СВЯЗЫВАЮЩИЕ ALK-1 и BMPR-2
|
EP3703751A2
(en)
|
2017-11-03 |
2020-09-09 |
Rubius Therapeutics, Inc. |
Compositions and methods related to therapeutic cell systems for tumor growth inhibition
|
MX2020004567A
(es)
|
2017-11-06 |
2020-08-13 |
Genentech Inc |
Metodos diagnosticos y terapeuticos para el cancer.
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
KR20200085828A
(ko)
|
2017-11-08 |
2020-07-15 |
젠코어 인코포레이티드 |
신규의 항-pd-1 서열을 사용한 이중특이적 및 단일특이적 항체
|
US11484573B2
(en)
|
2017-11-09 |
2022-11-01 |
Keros Therapeutics, Inc. |
Activin receptor type IIa variants and methods of use thereof
|
TWI800552B
(zh)
|
2017-11-10 |
2023-05-01 |
新加坡科技研究局 |
介白素2受體β(IL2Rβ)/共同γ鏈抗體
|
WO2019099838A1
(en)
|
2017-11-16 |
2019-05-23 |
Novartis Ag |
Combination therapies
|
WO2019100052A2
(en)
|
2017-11-20 |
2019-05-23 |
Compass Therapeutics Llc |
Cd137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
SG11202003443TA
(en)
|
2017-11-24 |
2020-05-28 |
Eucure Beijing Biopharma Co Ltd |
Anti-ox40 antibodies and uses thereof
|
EP3717011B1
(en)
|
2017-11-29 |
2022-12-07 |
CSL Limited |
Method of treating or preventing ischemia-reperfusion injury
|
CN111601820A
(zh)
|
2017-12-08 |
2020-08-28 |
阿根思公司 |
FcRn拮抗剂用于治疗全身性重症肌无力的用途
|
MX2020006125A
(es)
|
2017-12-14 |
2020-08-24 |
Hoffmann La Roche |
Uso de un anticuerpo biespecifico de cea cd3 y un antagonista de la union al eje de pd-1 en un regimen de dosificacion para tratar el cancer.
|
CN111655729B
(zh)
|
2017-12-19 |
2023-10-20 |
瑟罗泽恩奥普瑞汀公司 |
抗卷曲蛋白抗体和使用方法
|
EP3732201A4
(en)
|
2017-12-19 |
2022-04-20 |
Surrozen Operating, Inc. |
WNT SUBSTITUTION MOLECULES AND THEIR USES
|
SG11202005732XA
(en)
|
2017-12-19 |
2020-07-29 |
Xencor Inc |
Engineered il-2 fc fusion proteins
|
US11746150B2
(en)
|
2017-12-19 |
2023-09-05 |
Surrozen Operating, Inc. |
Anti-LRP5/6 antibodies and methods of use
|
US11802154B2
(en)
|
2017-12-20 |
2023-10-31 |
Alexion Pharmaceuticals, Inc. |
Humanized anti-CD200 antibodies and uses thereof
|
EP3502140A1
(en)
|
2017-12-21 |
2019-06-26 |
F. Hoffmann-La Roche AG |
Combination therapy of tumor targeted icos agonists with t-cell bispecific molecules
|
KR102575787B1
(ko)
|
2017-12-21 |
2023-09-08 |
에프. 호프만-라 로슈 아게 |
Hla-a2/wt1에 결합하는 항체
|
EP3728328A1
(en)
|
2017-12-22 |
2020-10-28 |
Argenx BVBA |
Bispecific antigen binding construct
|
EP3728321A1
(en)
|
2017-12-22 |
2020-10-28 |
F. Hoffmann-La Roche AG |
Use of pilra binding agents for treatment of a disease
|
US11945839B2
(en)
|
2017-12-22 |
2024-04-02 |
Hoffmann-La Roche Inc. |
Depletion of light chain mispaired antibody variants by hydrophobic interaction chromatography
|
CA3087061A1
(en)
|
2017-12-27 |
2019-07-04 |
Teneobio, Inc. |
Cd3-delta/epsilon heterodimer specific antibodies
|
TWI817974B
(zh)
|
2017-12-28 |
2023-10-11 |
日商中外製藥股份有限公司 |
細胞毒性誘導治療劑
|
TW201930358A
(zh)
|
2017-12-28 |
2019-08-01 |
大陸商南京傳奇生物科技有限公司 |
針對tigit之單域抗體及其變異體
|
US20220135687A1
(en)
|
2017-12-28 |
2022-05-05 |
Nanjing Legend Biotech Co., Ltd. |
Antibodies and variants thereof against pd-l1
|
CN111886246A
(zh)
|
2017-12-29 |
2020-11-03 |
艾莱克特有限责任公司 |
抗tmem106b抗体及其使用方法
|
EP3731865A1
(en)
|
2017-12-29 |
2020-11-04 |
F. Hoffmann-La Roche AG |
Method for improving vegf-receptor blocking selectivity of an anti-vegf antibody
|
CA3087149A1
(en)
|
2018-01-03 |
2019-07-11 |
Alpine Immune Sciences, Inc. |
Multi-domain immunomodulatory proteins and methods of use thereof
|
US20190330591A1
(en)
|
2018-01-10 |
2019-10-31 |
Rubius Therapeutics, Inc. |
Amplifiable rnas for therapeutic cell systems
|
US11067584B2
(en)
|
2018-01-12 |
2021-07-20 |
Genzyme Corporation |
Methods for the quantitation of polypeptides
|
KR20200120641A
(ko)
|
2018-01-15 |
2020-10-21 |
난징 레전드 바이오테크 씨오., 엘티디. |
Pd-1에 대한 단일-도메인 항체 및 이의 변이체
|
CA3088649A1
(en)
|
2018-01-16 |
2019-07-25 |
Lakepharma, Inc. |
Bispecific antibody that binds cd3 and another target
|
BR112020013405A2
(pt)
|
2018-01-25 |
2020-12-01 |
Acm Biolabs Pte Ltd. |
polimerossomas compreendendo um antígeno encapsulado solúvel, assim como métodos de sua fabricação e uso
|
LT3743088T
(lt)
|
2018-01-26 |
2022-12-27 |
F. Hoffmann-La Roche Ag |
Il-22 fc kompozicijos ir jų naudojimo būdai
|
KR20200115546A
(ko)
|
2018-01-26 |
2020-10-07 |
제넨테크, 인크. |
IL-22 Fc 융합 단백질 및 사용 방법
|
WO2019152715A1
(en)
|
2018-01-31 |
2019-08-08 |
Alector Llc |
Anti-ms4a4a antibodies and methods of use thereof
|
CA3090249A1
(en)
|
2018-01-31 |
2019-08-08 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
JP2021511782A
(ja)
|
2018-01-31 |
2021-05-13 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
安定化された免疫グロブリンドメイン
|
EP3746480A1
(en)
|
2018-01-31 |
2020-12-09 |
F. Hoffmann-La Roche AG |
Bispecific antibodies comprising an antigen-binding site binding to lag3
|
WO2019148412A1
(en)
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1/lag3 bispecific antibodies
|
FR3077296A1
(fr)
|
2018-02-01 |
2019-08-02 |
Laboratoire Francais Du Fractionnement Et Des Biotechnologies |
Dimeres de variants du facteur x
|
MX2020007527A
(es)
|
2018-02-06 |
2020-09-09 |
Hoffmann La Roche |
Tratamiento de enfermedades oftalmologicas.
|
MX2020008219A
(es)
|
2018-02-08 |
2020-10-22 |
Amgen Inc |
Formulacion farmaceutica de ph bajo.
|
KR20200118065A
(ko)
|
2018-02-08 |
2020-10-14 |
제넨테크, 인크. |
이중특이적 항원-결합 분자 및 이의 사용 방법
|
US11884733B2
(en)
|
2018-02-08 |
2024-01-30 |
Dragonfly Therapeutics, Inc. |
Antibody variable domains targeting the NKG2D receptor
|
WO2019153200A1
(zh)
|
2018-02-08 |
2019-08-15 |
北京韩美药品有限公司 |
抗pd-1/抗her2天然抗体结构样异源二聚体形式双特异抗体及其制备
|
KR20220098056A
(ko)
|
2018-02-09 |
2022-07-08 |
제넨테크, 인크. |
비만 세포 매개 염증성 질환에 대한 치료 및 진단 방법
|
TWI829667B
(zh)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合gprc5d之抗體
|
JP2021512624A
(ja)
|
2018-02-11 |
2021-05-20 |
ベイジン・ハンミ・ファーマシューティカル・カンパニー・リミテッドBeijing Hanmi Pharmaceutical Co., Ltd. |
抗pd−1/抗vegf天然抗体構造様ヘテロ二量体型二重特異性抗体及びその製造
|
EP3753956A4
(en)
|
2018-02-14 |
2021-12-22 |
Chugai Seiyaku Kabushiki Kaisha |
ANTIGEN BINDING MOLECULE AND COMBINATION
|
GB201802487D0
(en)
|
2018-02-15 |
2018-04-04 |
Argenx Bvba |
Cytokine combination therapy
|
AU2019226085A1
(en)
|
2018-02-21 |
2020-09-17 |
Genentech, Inc. |
Dosing for treatment with IL-22 Fc fusion proteins
|
KR102608723B1
(ko)
|
2018-02-23 |
2023-12-01 |
유큐(베이징) 바이오파마 코., 엘티디 |
항―pd-1 항체 및 그의 용도
|
WO2019168847A1
(en)
|
2018-02-27 |
2019-09-06 |
Incyte Corporation |
Imidazopyrimidines and triazolopyrimidines as a2a / a2b inhibitors
|
IL276896B2
(en)
|
2018-03-05 |
2024-06-01 |
Janssen Biotech Inc |
Methods for treating Crohn's disease with a specific anti-IL23 antibody
|
RS64690B1
(sr)
|
2018-03-13 |
2023-11-30 |
Zymeworks Bc Inc |
Konjugati biparatopskog anti-her2 antitela i leka i postupci za njihovu upotrebu
|
TWI841551B
(zh)
|
2018-03-13 |
2024-05-11 |
瑞士商赫孚孟拉羅股份公司 |
使用靶向4-1bb (cd137)之促效劑的組合療法
|
CA3092002A1
(en)
|
2018-03-13 |
2019-09-19 |
F. Hoffmann-La Roche Ag |
Therapeutic combination of 4-1 bb agonists with anti-cd20 antibodies
|
US20200040103A1
(en)
|
2018-03-14 |
2020-02-06 |
Genentech, Inc. |
Anti-klk5 antibodies and methods of use
|
AU2019235842B2
(en)
|
2018-03-14 |
2022-02-03 |
Surface Oncology, Inc. |
Antibodies that bind CD39 and uses thereof
|
US20210009711A1
(en)
|
2018-03-14 |
2021-01-14 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
US11485782B2
(en)
|
2018-03-14 |
2022-11-01 |
Beijing Xuanyi Pharmasciences Co., Ltd. |
Anti-claudin 18.2 antibodies
|
AU2019235523A1
(en)
|
2018-03-14 |
2020-10-29 |
Novimmune Sa |
Anti-CD3 epsilon antibodies and methods of use thereof
|
WO2019178362A1
(en)
|
2018-03-14 |
2019-09-19 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
TWI827585B
(zh)
|
2018-03-15 |
2024-01-01 |
日商中外製藥股份有限公司 |
對茲卡病毒具有交叉反應性的抗登革病毒抗體及其使用方法
|
WO2019175381A1
(en)
|
2018-03-16 |
2019-09-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antigenic peptides deriving from pcsk2 and uses thereof for the diagnosis and treatment of type 1 diabetes
|
WO2019175380A2
(en)
|
2018-03-16 |
2019-09-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antigenic peptides deriving from secretogranin v and uses thereof for the diagnosis and treatment of type 1 diabetes
|
WO2019175384A2
(en)
|
2018-03-16 |
2019-09-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antigenic peptides deriving from urocortin 3 and uses thereof for the diagnosis and treatment of type 1 diabetes
|
JP7438180B2
(ja)
|
2018-03-20 |
2024-02-26 |
ウーシー バイオロジクス アイルランド リミテッド |
新規抗lag-3抗体ポリペプチド
|
MX2020009774A
(es)
|
2018-03-21 |
2020-10-08 |
Alx Oncology Inc |
Anticuerpos contra proteína alfa reguladora de señal y métodos de uso.
|
WO2019183499A1
(en)
|
2018-03-22 |
2019-09-26 |
Surface Oncology, Inc. |
Anti-il-27 antibodies and uses thereof
|
GB201804701D0
(en)
|
2018-03-23 |
2018-05-09 |
Gammadelta Therapeutics Ltd |
Lymphocytes expressing heterologous targeting constructs
|
TWI842701B
(zh)
|
2018-03-24 |
2024-05-21 |
美商再生元醫藥公司 |
用於產生抗肽-mhc複合物之治療性抗體的經基因修飾的非人類動物、其製法與用途
|
SG11202008620VA
(en)
|
2018-03-26 |
2020-10-29 |
Regeneron Pharma |
Humanized rodents for testing therapeutic agents
|
WO2019185164A1
(en)
|
2018-03-29 |
2019-10-03 |
Hummingbird Bioscience Holdings Pte. Ltd. |
Her3 antigen-binding molecules
|
SG11202009542PA
(en)
|
2018-03-29 |
2020-10-29 |
Genentech Inc |
Modulating lactogenic activity in mammalian cells
|
US20190300610A1
(en)
|
2018-03-29 |
2019-10-03 |
Hummingbird Bioscience Pte. Ltd. |
Vista antigen-binding molecules
|
WO2019185163A1
(en)
|
2018-03-29 |
2019-10-03 |
Hummingbird Bioscience Holdings Pte. Ltd. |
Vista antigen-binding molecules
|
TW202003567A
(zh)
|
2018-03-30 |
2020-01-16 |
大陸商南京傳奇生物科技有限公司 |
針對lag-3之單一結構域抗體及其用途
|
TW202011029A
(zh)
|
2018-04-04 |
2020-03-16 |
美商建南德克公司 |
偵測及定量fgf21之方法
|
CA3096052A1
(en)
|
2018-04-04 |
2019-10-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
US10870691B2
(en)
|
2018-04-05 |
2020-12-22 |
Gilead Sciences, Inc. |
Antibodies and fragments thereof that bind hepatitis B virus protein X
|
EP3774916A2
(en)
|
2018-04-06 |
2021-02-17 |
Biolegend, Inc. |
Anti-tetraspanin 33 agents and compositions and methods for making and using the same
|
US10654944B2
(en)
|
2018-04-10 |
2020-05-19 |
Y-Biologics Inc. |
Cell engaging binding molecules
|
SG11202009804RA
(en)
|
2018-04-11 |
2020-11-27 |
Inhibrx Inc |
Multispecific polypeptide constructs having constrained cd3 binding and related methods and uses
|
WO2019200357A1
(en)
|
2018-04-12 |
2019-10-17 |
Surface Oncology, Inc. |
Biomarker for cd47 targeting therapeutics and uses therefor
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
CR20200459A
(es)
*
|
2018-04-13 |
2020-11-11 |
Hoffmann La Roche |
Moléculas de unión a antígeno dirigidas a her2 que comprendan 4-1bbl
|
CN112437777A
(zh)
|
2018-04-18 |
2021-03-02 |
Xencor股份有限公司 |
包含IL-15/IL-15RA Fc融合蛋白和TIM-3抗原结合结构域的靶向TIM-3的异源二聚体融合蛋白
|
WO2019204646A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Lag-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and lag-3 antigen binding domains
|
MA52289A
(fr)
|
2018-04-18 |
2021-02-24 |
Xencor Inc |
Protéines de fusion fc hétérodimères il-15/il-15ra et leurs utilisations
|
AR114789A1
(es)
|
2018-04-18 |
2020-10-14 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de los mismos
|
AR115052A1
(es)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
Anticuerpos multiespecíficos y utilización de los mismos
|
US11524991B2
(en)
|
2018-04-18 |
2022-12-13 |
Xencor, Inc. |
PD-1 targeted heterodimeric fusion proteins containing IL-15/IL-15Ra Fc-fusion proteins and PD-1 antigen binding domains and uses thereof
|
US20210047405A1
(en)
|
2018-04-27 |
2021-02-18 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
WO2019212965A1
(en)
|
2018-04-30 |
2019-11-07 |
Regeneron Pharmaceuticals, Inc. |
Antibodies, and bispecific antigen-binding molecules that bind her2 and/or aplp2, conjugates, and uses thereof
|
WO2019213282A1
(en)
|
2018-05-01 |
2019-11-07 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
EP3788071A1
(en)
|
2018-05-02 |
2021-03-10 |
The United States Of America, As Represented By The Secretary, Department of Health and Human Services |
Antibodies and methods for the diagnosis, prevention, and treatment of epstein barr virus infection
|
US20190345245A1
(en)
|
2018-05-11 |
2019-11-14 |
Janssen Biotech, Inc. |
Methods of Treating Crohn's Disease with Anti-IL23 Specific Antibody
|
EP3794022A1
(en)
|
2018-05-14 |
2021-03-24 |
Werewolf Therapeutics, Inc. |
Activatable cytokine polypeptides and methods of use thereof
|
SG11202011349PA
(en)
|
2018-05-14 |
2020-12-30 |
Werewolf Therapeutics Inc |
Activatable interleukin-2 polypeptides and methods of use thereof
|
MX2020012286A
(es)
|
2018-05-16 |
2021-04-28 |
Janssen Biotech Inc |
Metodos para tratar canceres y potenciar la eficacia de agentes terapeuticos para el redireccionamiento de celulas t.
|
CA3100071A1
(en)
|
2018-05-16 |
2019-11-21 |
Csl Limited |
Soluble complement receptor type 1 variants and uses thereof
|
SG11202011232VA
(en)
|
2018-05-17 |
2020-12-30 |
Regeneron Pharma |
Anti-cd63 antibodies, conjugates, and uses thereof
|
EP3810610A1
(en)
|
2018-05-18 |
2021-04-28 |
Incyte Corporation |
Fused pyrimidine derivatives as a2a / a2b inhibitors
|
CA3097512A1
(en)
|
2018-05-18 |
2019-11-21 |
F. Hoffmann-La Roche Ag |
Targeted intracellular delivery of large nucleic acids
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
US20200109195A1
(en)
|
2018-05-21 |
2020-04-09 |
Compass Therapeutics Llc |
Compositions and methods for enhancing the killing of target cells by nk cells
|
JP7337099B2
(ja)
|
2018-05-25 |
2023-09-01 |
アレクトル エルエルシー |
抗sirpa抗体およびその使用法
|
EP3801769A1
(en)
|
2018-05-25 |
2021-04-14 |
Novartis AG |
Combination therapy with chimeric antigen receptor (car) therapies
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
KR20210056288A
(ko)
|
2018-06-01 |
2021-05-18 |
타유 후아시아 바이오테크 메디컬 그룹 컴퍼니 리미티드 |
질환 또는 병태를 치료하기 위한 조성물 및 그의 용도
|
BR112020024249A2
(pt)
|
2018-06-01 |
2021-03-02 |
Compugen Ltd. |
anticorpo biespecífico anti-pvrig/anti-tigit, composição, composição de ácido nucleico, composição de vetor de expressão, célula hospedeira, métodos para produzir um anticorpo biespecífico anti-pvrig/anti-tigit, para ativação de células t de um paciente, para ativação de células t citotóxicas de um paciente, para ativação de células nk de um paciente, para ativação de células t gama delta de um paciente, para ativação de células th1 de um paciente, para diminuir ou eliminar o número de células e/ou a atividade de pelo menos uma das células t reguladoras em um paciente, para aumentar a produção de interferon-gama e/ou a secreção de citocinas pró-inflamatórias em um paciente e para tratamento de câncer em um paciente, anticorpo anti-pvrig, anticorpo anti-tigit, e, vetor de expressão.
|
EP3802611A2
(en)
|
2018-06-01 |
2021-04-14 |
Novartis AG |
Binding molecules against bcma and uses thereof
|
MA52764A
(fr)
|
2018-06-08 |
2021-04-28 |
Alector Llc |
Anticorps anti-siglec-7 et leurs méthodes d'utilisation
|
WO2019237035A1
(en)
|
2018-06-08 |
2019-12-12 |
Intellia Therapeutics, Inc. |
Compositions and methods for immunooncology
|
AU2019280900A1
(en)
|
2018-06-09 |
2020-11-19 |
Boehringer Ingelheim International Gmbh |
DLL3-CD3 bispecific antibodies
|
EP3806962A1
(en)
|
2018-06-13 |
2021-04-21 |
Novartis AG |
Bcma chimeric antigen receptors and uses thereof
|
FR3082427B1
(fr)
|
2018-06-14 |
2020-09-25 |
Lab Francais Du Fractionnement |
Combinaison de facteur vii et d'un anticorps bispecifique anti-facteurs ix et x
|
KR102444180B1
(ko)
|
2018-06-14 |
2022-09-16 |
리제너론 파마슈티칼스 인코포레이티드 |
면역글로불린 중쇄 암호화 서열에서 dh-dh 재배열 가능한 비인간 동물
|
US12065476B2
(en)
|
2018-06-15 |
2024-08-20 |
Alpine Immune Sciences, Inc. |
PD-1 variant immunomodulatory proteins and uses thereof
|
SG11202012342WA
(en)
|
2018-06-18 |
2021-01-28 |
Eureka Therapeutics Inc |
Constructs targeting prostate-specific membrane antigen (psma) and uses thereof
|
JP2021529516A
(ja)
|
2018-06-18 |
2021-11-04 |
アンウィタ バイオサイエンシス, インク. |
サイトカイン融合タンパク質及びその使用
|
CA3104295A1
(en)
|
2018-06-19 |
2019-12-26 |
Atarga, Llc |
Antibody molecules to complement component 5 and uses thereof
|
WO2019246312A1
(en)
|
2018-06-20 |
2019-12-26 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with an immunomodulator
|
US20230009902A1
(en)
|
2018-06-20 |
2023-01-12 |
Progenity, Inc. |
Treatment of a disease or condition in a tissue orginating from the endoderm
|
US20200095322A1
(en)
|
2018-06-20 |
2020-03-26 |
Incyte Corporation |
Anti-pd-1 antibodies and uses thereof
|
US20210261669A1
(en)
|
2018-06-20 |
2021-08-26 |
Chugai Seiyaku Kabushiki Kaisha |
Method for activating immune response of target cell and composition therefor
|
WO2019244107A1
(en)
|
2018-06-21 |
2019-12-26 |
Daiichi Sankyo Company, Limited |
Compositions including cd3 antigen binding fragments and uses thereof
|
EA202190092A1
(ru)
|
2018-06-21 |
2021-05-18 |
Юманити Терапьютикс, Инк. |
Композиции и способы лечения и профилактики неврологических расстройств
|
CN112654633A
(zh)
|
2018-06-22 |
2021-04-13 |
科优基因公司 |
基于细胞因子的可生物活化药物及其使用方法
|
US20200030443A1
(en)
|
2018-06-23 |
2020-01-30 |
Genentech, Inc. |
Methods of treating lung cancer with a pd-1 axis binding antagonist, a platinum agent, and a topoisomerase ii inhibitor
|
US11241438B2
(en)
|
2018-06-29 |
2022-02-08 |
Incyte Corporation |
Formulations of an AXL/MER inhibitor
|
CN112384532A
(zh)
|
2018-06-29 |
2021-02-19 |
艾利妥 |
抗SIRP-β1抗体及其使用方法
|
BR112020026724A2
(pt)
|
2018-07-02 |
2021-03-30 |
Amgen Inc. |
Proteína de ligação ao antígeno anti-steap1
|
US11845797B2
(en)
|
2018-07-03 |
2023-12-19 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
PE20210685A1
(es)
|
2018-07-03 |
2021-04-08 |
Gilead Sciences Inc |
Anticuerpos que se dirigen al gp120 de vih y metodos de uso
|
EP3818082A1
(en)
|
2018-07-04 |
2021-05-12 |
F. Hoffmann-La Roche AG |
Novel bispecific agonistic 4-1bb antigen binding molecules
|
KR20210049090A
(ko)
|
2018-07-05 |
2021-05-04 |
인사이트 코포레이션 |
A2a/a2b 억제제로서 융합된 피라진 유도체
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
WO2020014306A1
(en)
|
2018-07-10 |
2020-01-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
US11396546B2
(en)
|
2018-07-13 |
2022-07-26 |
Alector Llc |
Anti-Sortilin antibodies and methods of use thereof
|
TW202019965A
(zh)
|
2018-07-16 |
2020-06-01 |
美商安進公司 |
治療多發性骨髓瘤之方法
|
CN112839644A
(zh)
|
2018-07-18 |
2021-05-25 |
豪夫迈·罗氏有限公司 |
用pd-1轴结合拮抗剂、抗代谢物和铂剂治疗肺癌的方法
|
EP3824295A4
(en)
|
2018-07-18 |
2022-04-27 |
Janssen Biotech, Inc. |
PREDICTORS OF PROLONGED RESPONSE AFTER TREATMENT WITH AN ANTI-IL23 SPECIFIC ANTIBODY
|
SG11202100510PA
(en)
|
2018-07-20 |
2021-02-25 |
Eucure Beijing Biopharma Co Ltd |
Anti-cd40 antibodies and uses thereof
|
MX2021000745A
(es)
|
2018-07-20 |
2021-03-26 |
Surface Oncology Inc |
Composiciones anti-cd112r y metodos.
|
TW202035451A
(zh)
|
2018-07-24 |
2020-10-01 |
美商英伊布里克斯公司 |
含有受限cd3結合域及受體結合區之多重特異性多肽構築體及其使用方法
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
MA53328A
(fr)
|
2018-07-27 |
2021-06-09 |
Alector Llc |
Anticorps anti-siglec-5 et leurs procédés d'utilisation
|
JP7504027B2
(ja)
|
2018-08-03 |
2024-06-21 |
中外製薬株式会社 |
互いに連結された2つの抗原結合ドメインを含む抗原結合分子
|
AR115925A1
(es)
|
2018-08-08 |
2021-03-10 |
Genentech Inc |
Uso de derivados de triptófano y l-metionina para formulación de proteínas
|
EP3833442A2
(en)
|
2018-08-09 |
2021-06-16 |
Compass Therapeutics LLC |
Antibodies that bind cd277 and uses thereof
|
WO2020033923A1
(en)
|
2018-08-09 |
2020-02-13 |
Compass Therapeutics Llc |
Antigen binding agents that bind cd277 and uses thereof
|
CA3051549A1
(en)
|
2018-08-09 |
2020-02-09 |
Regeneron Pharmaceuticals, Inc. |
Methods for assessing binding affinity of an antibody variant to the neonatal fc receptor
|
WO2020033925A2
(en)
|
2018-08-09 |
2020-02-13 |
Compass Therapeutics Llc |
Antibodies that bind cd277 and uses thereof
|
WO2020032230A1
(ja)
|
2018-08-10 |
2020-02-13 |
中外製薬株式会社 |
抗cd137抗原結合分子およびその使用
|
CN113166241A
(zh)
|
2018-08-16 |
2021-07-23 |
约翰霍普金斯大学 |
人类znt8抗体
|
CN112638946A
(zh)
|
2018-08-16 |
2021-04-09 |
坎塔吉亚有限责任公司 |
抗il1rap抗体组合物
|
TW202021618A
(zh)
|
2018-08-17 |
2020-06-16 |
美商23與我有限公司 |
抗il1rap抗體及其使用方法
|
WO2020045545A1
(ja)
|
2018-08-29 |
2020-03-05 |
中外製薬株式会社 |
抗体半分子、および抗体半分子のホモ二量体形成を抑制する方法
|
EP3844192A1
(en)
|
2018-08-30 |
2021-07-07 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
WO2020047452A2
(en)
|
2018-08-31 |
2020-03-05 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
EP3844265A2
(en)
|
2018-08-31 |
2021-07-07 |
Novartis AG |
Methods of making chimeric antigen receptor-expressing cells
|
CN113801229A
(zh)
|
2018-08-31 |
2021-12-17 |
艾利妥 |
抗cd33抗体及其使用方法
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
GB2576914A
(en)
|
2018-09-06 |
2020-03-11 |
Kymab Ltd |
Antigen-binding molecules comprising unpaired variable domains produced in mammals
|
MX2021002750A
(es)
|
2018-09-12 |
2021-05-12 |
Eucure Beijing Biopharma Co Ltd |
Anticuerpos anti-tnfrsf9 y usos de los mismos.
|
WO2020053325A1
(en)
|
2018-09-12 |
2020-03-19 |
Acm Biolabs Pte Ltd |
Polymersomes comprising a covalently bound antigen as well as methods of making and uses thereof
|
EP3849565A4
(en)
|
2018-09-12 |
2022-12-28 |
Fred Hutchinson Cancer Research Center |
REDUCING CD33 EXPRESSION FOR SELECTIVE PROTECTION OF THERAPEUTIC CELLS
|
WO2020061376A2
(en)
|
2018-09-19 |
2020-03-26 |
Alpine Immune Sciences, Inc. |
Methods and uses of variant cd80 fusion proteins and related constructs
|
AU2019342099A1
(en)
|
2018-09-19 |
2021-04-08 |
Genentech, Inc. |
Therapeutic and diagnostic methods for bladder cancer
|
EP4249917A3
(en)
|
2018-09-21 |
2023-11-08 |
F. Hoffmann-La Roche AG |
Diagnostic methods for triple-negative breast cancer
|
CA3155293A1
(en)
|
2018-09-24 |
2020-04-02 |
The Medical College Of Wisconsin, Inc. |
System and method for the development of cd30 bispecific antibodies for immunotherapy of cd30+ malignancies
|
WO2020068557A1
(en)
|
2018-09-25 |
2020-04-02 |
BioLegend, Inc. |
Anti-tlr9 agents and compositions and methods for making and using the same
|
CA3114038A1
(en)
|
2018-09-25 |
2020-04-02 |
Harpoon Therapeutics, Inc. |
Dll3 binding proteins and methods of use
|
SG11202102777PA
(en)
|
2018-09-27 |
2021-04-29 |
Xilio Development Inc |
Masked cytokine polypeptides
|
EP3856779A1
(en)
|
2018-09-28 |
2021-08-04 |
Novartis AG |
Cd22 chimeric antigen receptor (car) therapies
|
WO2020069409A1
(en)
|
2018-09-28 |
2020-04-02 |
Novartis Ag |
Cd19 chimeric antigen receptor (car) and cd22 car combination therapies
|
AU2019355252A1
(en)
|
2018-10-01 |
2021-04-01 |
F. Hoffmann-La Roche Ag |
Bispecific antigen binding molecules comprising anti-FAP clone 212
|
EP3861025A1
(en)
|
2018-10-01 |
2021-08-11 |
F. Hoffmann-La Roche AG |
Bispecific antigen binding molecules with trivalent binding to cd40
|
SG11202103192RA
(en)
|
2018-10-03 |
2021-04-29 |
Xencor Inc |
Il-12 heterodimeric fc-fusion proteins
|
AU2019354105A1
(en)
|
2018-10-04 |
2021-04-29 |
Genmab Holding B.V. |
Pharmaceutical compositions comprising bispecific anti-CD37 antibodies
|
TW202028244A
(zh)
|
2018-10-09 |
2020-08-01 |
美商建南德克公司 |
用於確定突觸形成之方法及系統
|
WO2020076853A1
(en)
|
2018-10-09 |
2020-04-16 |
Sanofi |
Trispecific anti-cd38, anti-cd28, and anti-cd3 binding proteins and methods of use for treating viral infection
|
WO2020076992A1
(en)
|
2018-10-11 |
2020-04-16 |
Inhibrx, Inc. |
5t4 single domain antibodies and therapeutic compositions thereof
|
CN113166262A
(zh)
|
2018-10-11 |
2021-07-23 |
英伊布里克斯公司 |
Pd-1单结构域抗体及其治疗组合物
|
CN113166263A
(zh)
|
2018-10-11 |
2021-07-23 |
印希比股份有限公司 |
Dll3单域抗体及其治疗性组合物
|
EP3864044A1
(en)
|
2018-10-11 |
2021-08-18 |
Inhibrx, Inc. |
B7h3 single domain antibodies and therapeutic compositions thereof
|
WO2020077276A2
(en)
|
2018-10-12 |
2020-04-16 |
Xencor, Inc. |
Pd-1 targeted il-15/il-15ralpha fc fusion proteins and uses in combination therapies thereof
|
CA3116324A1
(en)
|
2018-10-18 |
2020-04-23 |
Genentech, Inc. |
Diagnostic and therapeutic methods for sarcomatoid kidney cancer
|
WO2020086758A1
(en)
|
2018-10-23 |
2020-04-30 |
Dragonfly Therapeutics, Inc. |
Heterodimeric fc-fused proteins
|
AU2019365238A1
(en)
|
2018-10-24 |
2021-05-13 |
F. Hoffmann-La Roche Ag |
Conjugated chemical inducers of degradation and methods of use
|
GB201817354D0
(en)
|
2018-10-25 |
2018-12-12 |
Hummingbird Bioscience Pte Ltd |
Engineered FC
|
CN112955240B
(zh)
|
2018-10-25 |
2022-09-16 |
豪夫迈·罗氏有限公司 |
抗体FcRn结合的修饰
|
WO2020084034A1
(en)
|
2018-10-26 |
2020-04-30 |
F. Hoffmann-La Roche Ag |
Multispecific antibody screening method using recombinase mediated cassette exchange
|
WO2020092455A2
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Car t cell transcriptional atlas
|
CN113508135A
(zh)
|
2018-10-29 |
2021-10-15 |
比奥根Ma公司 |
增强血脑屏障转运的人源化和稳定化的fc5变体
|
KR102467349B1
(ko)
|
2018-10-29 |
2022-11-16 |
에프. 호프만-라 로슈 아게 |
항체 제형
|
WO2020089437A1
(en)
|
2018-10-31 |
2020-05-07 |
Engmab Sàrl |
Combination therapy
|
EP3877407A1
(en)
|
2018-11-05 |
2021-09-15 |
F. Hoffmann-La Roche AG |
Methods of producing two chain proteins in prokaryotic host cells
|
AU2019375014A1
(en)
|
2018-11-06 |
2021-05-27 |
BioNTech SE |
Antibody formulation
|
TW202039557A
(zh)
|
2018-11-09 |
2020-11-01 |
新加坡商優其洛伊生物私人有限公司 |
介白素2受體β(IL2Rβ)/共同γ鏈抗體
|
WO2020094834A1
(en)
|
2018-11-09 |
2020-05-14 |
Euchloe Bio Pte. Ltd. |
Il2rbeta/common gamma chain antibodies
|
AU2019379576A1
(en)
|
2018-11-13 |
2021-06-03 |
Compass Therapeutics Llc |
Multispecific binding constructs against checkpoint molecules and uses thereof
|
JP7469305B2
(ja)
|
2018-11-19 |
2024-04-16 |
バイオサイトジェン ファーマシューティカルズ (ベイジン) カンパニー リミテッド |
抗pd-1抗体およびその使用
|
US20230183379A1
(en)
|
2018-11-20 |
2023-06-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Bispecific antibody targeting transferrin receptor 1 and soluble antigen
|
BR112021009287A2
(pt)
|
2018-11-20 |
2021-10-26 |
Janssen Biotech, Inc. |
Método seguro e eficaz para tratar psoríase com anticorpo específico anti-il-23
|
CA3120868A1
(en)
|
2018-11-30 |
2020-06-04 |
Alpine Immune Sciences, Inc. |
Cd86 variant immunomodulatory proteins and uses thereof
|
WO2020117988A1
(en)
|
2018-12-04 |
2020-06-11 |
Tolero Pharmaceuticals, Inc. |
Cdk9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
|
AU2019392711A1
(en)
|
2018-12-05 |
2021-05-20 |
Morphosys Ag |
Multispecific antigen-binding molecules
|
US20220098310A1
(en)
|
2018-12-06 |
2022-03-31 |
Alexion Pharmaceuticals, Inc. |
Anti-alk2 antibodies and uses thereof
|
BR112021010908A2
(pt)
|
2018-12-06 |
2021-08-31 |
Genentech, Inc. |
Método para tratamento de linfoma difuso de grandes células b, kit e imunoconjugado
|
JP2022513198A
(ja)
|
2018-12-10 |
2022-02-07 |
ジェネンテック, インコーポレイテッド |
Fc含有タンパク質への部位特異的コンジュゲーションのための光架橋性ペプチド
|
WO2020132646A1
(en)
|
2018-12-20 |
2020-06-25 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and nkg2d antigen binding domains
|
JP2022514280A
(ja)
|
2018-12-20 |
2022-02-10 |
ノバルティス アーゲー |
Mdm2阻害剤のための延長低用量レジメン
|
TW202035442A
(zh)
|
2018-12-20 |
2020-10-01 |
美商建南德克公司 |
經修飾之抗體Fc及其使用方法
|
AR117327A1
(es)
|
2018-12-20 |
2021-07-28 |
23Andme Inc |
Anticuerpos anti-cd96 y métodos de uso de estos
|
WO2020128972A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
PT3723858T
(pt)
|
2018-12-21 |
2022-02-02 |
Kymab Ltd |
Anticorpo biespecífico fixaxfx com cadeia leve comum
|
SG11202106100VA
(en)
|
2018-12-21 |
2021-07-29 |
23Andme Inc |
Anti-il-36 antibodies and methods of use thereof
|
SG11202102859TA
(en)
|
2018-12-21 |
2021-04-29 |
Hoffmann La Roche |
Antibodies binding to cd3
|
TW202039567A
(zh)
|
2018-12-21 |
2020-11-01 |
瑞士商赫孚孟拉羅股份公司 |
靶向腫瘤之促效cd28抗原結合分子
|
KR20210107025A
(ko)
|
2018-12-21 |
2021-08-31 |
제넨테크, 인크. |
세포사멸에 내성인 세포주를 사용한 폴리펩티드 생산 방법
|
TW202030204A
(zh)
|
2018-12-21 |
2020-08-16 |
瑞士商赫孚孟拉羅股份公司 |
靶向腫瘤之超促效cd28抗原結合分子
|
EP3674316A1
(en)
|
2018-12-24 |
2020-07-01 |
Sanofi |
Multispecific binding proteins with mutant fab domains
|
WO2020136566A1
(en)
|
2018-12-24 |
2020-07-02 |
Sanofi |
Multispecific binding proteins with mutant fab domains
|
US11739160B2
(en)
|
2018-12-24 |
2023-08-29 |
Sanofi |
PseudoFab-based multispecific binding proteins
|
EP3674319A1
(en)
|
2018-12-24 |
2020-07-01 |
Sanofi |
Pseudofab-based multispecific binding proteins
|
CN111378044B
(zh)
|
2018-12-28 |
2022-07-15 |
长春金赛药业有限责任公司 |
抗体融合蛋白、制备方法及其应用
|
CN111378045B
(zh)
|
2018-12-28 |
2022-08-02 |
长春金赛药业有限责任公司 |
二价双特异性抗体及其制备方法、编码基因、宿主细胞、组合物
|
EP3902560A1
(en)
|
2018-12-28 |
2021-11-03 |
F. Hoffmann-La Roche AG |
A peptide-mhc-i-antibody fusion protein for therapeutic use in a patient with amplified immune response
|
JP7241888B2
(ja)
|
2018-12-30 |
2023-03-17 |
エフ. ホフマン-ラ ロシュ アーゲー |
pH勾配SPRに基づく結合アッセイ
|
WO2020142740A1
(en)
|
2019-01-04 |
2020-07-09 |
Resolve Therapeutics, Llc |
Treatment of sjogren's disease with nuclease fusion proteins
|
BR112021013507A2
(pt)
|
2019-01-10 |
2021-11-16 |
Janssen Biotech Inc |
Neoantígenos da próstata e seus usos
|
SG11202107538VA
(en)
|
2019-01-16 |
2021-08-30 |
Compass Therapeutics Llc |
Formulations of antibodies that bind human cd137 and uses thereof
|
CA3127025A1
(en)
|
2019-01-18 |
2020-07-23 |
Janssen Biotech, Inc. |
Gprc5d chimeric antigen receptors and cells expressing the same
|
WO2020154410A1
(en)
|
2019-01-23 |
2020-07-30 |
Genentech, Inc. |
Methods of producing multimeric proteins in eukaryotic host cells
|
JPWO2020153467A1
(ja)
|
2019-01-24 |
2021-12-02 |
中外製薬株式会社 |
新規がん抗原及びそれらの抗原に対する抗体
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
CN113840625A
(zh)
|
2019-01-29 |
2021-12-24 |
夏尔-Nps医药品有限公司 |
甲状旁腺激素变体
|
TWI829857B
(zh)
|
2019-01-29 |
2024-01-21 |
美商英塞特公司 |
作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
|
WO2020165834A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
EP3924054A1
(en)
|
2019-02-15 |
2021-12-22 |
Novartis AG |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
CA3125380A1
(en)
|
2019-02-18 |
2020-08-27 |
Biocytogen Pharmaceuticals (Beijing) Co., Ltd. |
Genetically modified non-human animals with humanized immunoglobulin locus
|
WO2020169698A1
(en)
|
2019-02-21 |
2020-08-27 |
F. Hoffmann-La Roche Ag |
Sensitization of cancer cells to tnf by bet inhibition
|
EP3927745A1
(en)
|
2019-02-21 |
2021-12-29 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to t cells and uses thereof to treat autoimmune disorders
|
CN113811549A
(zh)
|
2019-02-21 |
2021-12-17 |
Xencor股份有限公司 |
非靶向和靶向性il-10 fc融合蛋白
|
WO2020172596A1
(en)
|
2019-02-21 |
2020-08-27 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and thereof
|
CA3130508A1
(en)
|
2019-02-21 |
2020-08-27 |
Marengo Therapeutics, Inc. |
Antibody molecules that bind to nkp30 and uses thereof
|
GB2599229B
(en)
|
2019-02-21 |
2024-04-24 |
Marengo Therapeutics Inc |
Multifunctional molecules that bind to calreticulin and uses thereof
|
WO2020172571A1
(en)
|
2019-02-21 |
2020-08-27 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to t cell related cancer cells and uses thereof
|
US11639388B2
(en)
*
|
2019-02-22 |
2023-05-02 |
Wuhan Yzy Biopharma Co., Ltd. |
CD3 antigen binding fragment and application thereof
|
US20220088075A1
(en)
|
2019-02-22 |
2022-03-24 |
The Trustees Of The University Of Pennsylvania |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
JP2022523204A
(ja)
|
2019-02-25 |
2022-04-21 |
ノバルティス アーゲー |
ウイルス送達のためのメソポーラスシリカ粒子組成物
|
CN114173875A
(zh)
|
2019-03-01 |
2022-03-11 |
Xencor股份有限公司 |
结合enpp3和cd3的异二聚抗体
|
US20220235144A1
(en)
|
2019-03-04 |
2022-07-28 |
Qilu Puget Sound Biotherapeutics Corporation |
Anti-sirp-alpha antibodies
|
WO2020181140A1
(en)
|
2019-03-05 |
2020-09-10 |
Maverick Therapeutics, Inc. |
Constrained conditionally activated binding proteins
|
CN114173876A
(zh)
|
2019-03-05 |
2022-03-11 |
武田药品工业有限公司 |
含有靶向肿瘤抗原的Fc区和部分的条件性活化的结合蛋白质
|
JP7402247B2
(ja)
|
2019-03-08 |
2023-12-20 |
ジェネンテック, インコーポレイテッド |
細胞外小胞の膜結合タンパク質を検出及び定量化するための方法
|
AU2020236015A1
(en)
|
2019-03-14 |
2021-09-09 |
Genentech, Inc. |
Treatment of cancer with HER2XCD3 bispecific antibodies in combination with anti-HER2 MAB
|
JP7379654B2
(ja)
|
2019-03-15 |
2023-11-14 |
カーティザン セラピューティクス,インコーポレーテッド |
抗bcmaキメラ抗原受容体
|
EP3943108A4
(en)
|
2019-03-19 |
2023-01-04 |
Chugai Seiyaku Kabushiki Kaisha |
ANTIGEN-BINDING MOLECULE CONTAINING AN ANTIGEN-BINDING DOMAIN WHOSE ANTIGEN-BINDING ACTIVITY IS ALTERED DEPENDING ON THE MTA, AND BANK FOR OBTAINING SUCH ANTIGEN-BINDING DOMAIN
|
US11793802B2
(en)
|
2019-03-20 |
2023-10-24 |
Sumitomo Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (AML) with venetoclax failure
|
CN114174334A
(zh)
|
2019-03-22 |
2022-03-11 |
反射制药有限公司 |
针对vegf的d-肽化合物
|
WO2020198075A2
(en)
|
2019-03-22 |
2020-10-01 |
Reflexion Pharmaceuticals, Inc. |
Multivalent d-peptidic compounds for target proteins
|
EP3948281A1
(en)
|
2019-03-29 |
2022-02-09 |
F. Hoffmann-La Roche AG |
Spr-based binding assay for the functional analysis of multivalent molecules
|
EP3946593A1
(en)
|
2019-03-29 |
2022-02-09 |
Atarga, LLC |
Anti fgf23 antibody
|
JP7412440B2
(ja)
|
2019-03-29 |
2024-01-12 |
エフ. ホフマン-ラ ロシュ アーゲー |
アビド結合多重特異性抗体を作製する方法
|
KR20220005471A
(ko)
|
2019-04-08 |
2022-01-13 |
바이오젠 엠에이 인코포레이티드 |
항-인테그린 항체 및 이의 용도
|
US11613576B2
(en)
|
2019-04-09 |
2023-03-28 |
Sanofi |
Trispecific binding proteins, methods, and uses thereof
|
JP2022527565A
(ja)
|
2019-04-12 |
2022-06-02 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
CEA CD3二重特異性抗体及びWntシグナル伝達阻害剤を使用するがんの治療
|
JP7301155B2
(ja)
|
2019-04-12 |
2023-06-30 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
リポカリンムテインを含む二重特異性抗原結合分子
|
WO2020210678A1
(en)
|
2019-04-12 |
2020-10-15 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
AU2020257238A1
(en)
|
2019-04-17 |
2021-12-02 |
Alpine Immune Sciences, Inc. |
Methods and uses of variant ICOS Ligand (ICOSL) fusion proteins
|
CN113711037A
(zh)
|
2019-04-18 |
2021-11-26 |
基因泰克公司 |
抗体效力测定
|
AU2020258480A1
(en)
|
2019-04-19 |
2021-10-21 |
Genentech, Inc. |
Anti-mertk antibodies and their methods of use
|
US20220251152A1
(en)
|
2019-04-24 |
2022-08-11 |
Novartis Ag |
Compositions and methods for selective protein degradation
|
KR20220005031A
(ko)
|
2019-04-25 |
2022-01-12 |
에프. 호프만-라 로슈 아게 |
폴리펩티드 사슬 교환에 의한 항체-유래된 폴리펩티드의 산출
|
TW202106715A
(zh)
|
2019-04-25 |
2021-02-16 |
瑞士商赫孚孟拉羅股份公司 |
藉由多肽鏈交換活化之治療性多特異性多肽
|
KR20220004062A
(ko)
|
2019-04-25 |
2022-01-11 |
에프. 호프만-라 로슈 아게 |
반감기가 연장된 활성화 가능한 치료용 다중특이적 폴리펩티드
|
KR20220005568A
(ko)
|
2019-05-09 |
2022-01-13 |
제넨테크, 인크. |
항체의 제조 방법
|
CN113811770B
(zh)
|
2019-05-13 |
2024-06-28 |
豪夫迈·罗氏有限公司 |
抑制干扰的药代动力学免疫测定
|
SG11202112541RA
(en)
|
2019-05-14 |
2021-12-30 |
Werewolf Therapeutics Inc |
Separation moieties and methods and use thereof
|
MX2021013825A
(es)
|
2019-05-14 |
2022-01-18 |
Genentech Inc |
Procedimientos de uso de inmunoconjugados anti-cd79b para tratar el linfoma folicular.
|
EP3969043A1
(en)
|
2019-05-15 |
2022-03-23 |
Neotx Therapeutics Ltd. |
Cancer treatment
|
JP2022532381A
(ja)
|
2019-05-16 |
2022-07-14 |
プロサイセデクス インコーポレイティド |
Vcam-1及びカルプロテクチンのための分析検出方法
|
WO2020232295A1
(en)
|
2019-05-16 |
2020-11-19 |
Procisedx Inc. |
An assay method for the detection of vcam-1 and alpha-2-macroglobulin in blood
|
EP3969119A1
(en)
|
2019-05-17 |
2022-03-23 |
Xencor, Inc. |
Il-7-fc-fusi0n proteins
|
WO2020236797A1
(en)
|
2019-05-21 |
2020-11-26 |
Novartis Ag |
Variant cd58 domains and uses thereof
|
UY38701A
(es)
|
2019-05-21 |
2020-12-31 |
Novartis Ag |
Moléculas de unión a cd19, conjugados, composiciones que las comprenden y usos de las mismas
|
US20220396631A1
(en)
|
2019-05-21 |
2022-12-15 |
Lu HUANG |
Trispecific binding molecules against bcma and uses thereof
|
JP2022534227A
(ja)
|
2019-05-23 |
2022-07-28 |
プロサイセデクス インコーポレイティド |
ヒト血清アルブミン、ビタミンd、c反応性タンパク質、及び抗トランスグルタミナーゼ自己抗体の検出のためのアッセイ方法
|
JP2022534020A
(ja)
|
2019-05-23 |
2022-07-27 |
ヤンセン バイオテツク,インコーポレーテツド |
Il-23及びtnfアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
|
CN114174344A
(zh)
|
2019-05-30 |
2022-03-11 |
美国安进公司 |
工程改造铰链区以驱动抗体二聚化
|
BR112021024003A2
(pt)
|
2019-05-31 |
2022-04-19 |
Alx Oncology Inc |
Métodos de tratamento de câncer com fusão sirp alfa-fc em combinação com um inibidor de checkpoint imunológico
|
WO2020245677A1
(en)
|
2019-06-03 |
2020-12-10 |
Janssen Biotech, Inc. |
Anti-tnf antibodies, compositions, and methods for the treatment of active ankylosing spondylitis
|
BR112021023735A2
(pt)
|
2019-06-05 |
2022-01-04 |
Chugai Pharmaceutical Co Ltd |
Molécula de ligação de sítio de clivagem de anti-corpo
|
TW202112799A
(zh)
|
2019-06-05 |
2021-04-01 |
美商建南德克公司 |
過載層析管柱之再生方法
|
JP2022535125A
(ja)
|
2019-06-06 |
2022-08-04 |
プロサイセデクス インコーポレイティド |
血中ヘモグロビンA1C(HbA1c)の検出
|
KR20220019018A
(ko)
|
2019-06-07 |
2022-02-15 |
아르제넥스 비브이비에이 |
피하 투여에 적합한 FcRn 억제제의 약학적 제형
|
CR20220008A
(es)
|
2019-06-10 |
2022-02-11 |
Chugai Pharmaceutical Co Ltd |
Molécula de unión al antígeno anti-células t para usarse en combinación con un inhibidor de citocinas
|
JP7512310B2
(ja)
|
2019-06-11 |
2024-07-08 |
アレクトル エルエルシー |
治療に使用するための抗ソルチリン抗体
|
KR20220020810A
(ko)
|
2019-06-14 |
2022-02-21 |
테네오바이오, 인코포레이티드 |
Cd22와 cd3에 결합하는 다중특이적 중쇄 항체
|
JP7410983B2
(ja)
|
2019-06-19 |
2024-01-10 |
エフ. ホフマン-ラ ロシュ アーゲー |
Cre mRNAを使用した標的指向性組込みによるタンパク質発現細胞の作製のための方法
|
EP3986927A1
(en)
|
2019-06-19 |
2022-04-27 |
F. Hoffmann-La Roche AG |
Method for the generation of a multivalent, bispecific antibody expressing cell by targeted integration of multiple expression cassettes in a defined organization
|
BR112021025436A2
(pt)
|
2019-06-19 |
2022-02-01 |
Hoffmann La Roche |
Métodos para produzir um anticorpo biespecífico trivalente, biespecífico bivalente, biespecífico multivalente, para produzir uma célula de mamífero recombinante e para produzir um anticorpo trivalente, ácidos desoxirribonucleicos, usos de um ácido desoxirribonucleico, células de mamífero recombinante, composições e uso de mrna de recombinase cre
|
AU2020296247A1
(en)
|
2019-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Method for the generation of a trivalent antibody expressing cell by targeted integration of multiple expression cassettes in a defined organization
|
MX2021015538A
(es)
|
2019-06-19 |
2022-02-10 |
Hoffmann La Roche |
Metodo para la generacion de una celula que expresa un anticuerpo biespecifico bivalente mediante la integracion dirigida de multiples casetes de expresion en una organizacion definida.
|
CN116987197A
(zh)
|
2019-06-20 |
2023-11-03 |
成都恩沐生物科技有限公司 |
共价多特异性抗体
|
WO2020261093A1
(en)
|
2019-06-24 |
2020-12-30 |
Novartis Ag |
Dosing regimen and combination therapies for multispecific antibodies targeting b-cell maturation antigen
|
JP2022540764A
(ja)
|
2019-06-25 |
2022-09-20 |
プロサイセデクス インコーポレイティド |
抗TNFα生物製剤および抗薬剤抗体の検出
|
BR112021026293A2
(pt)
|
2019-06-26 |
2022-03-03 |
Hoffmann La Roche |
Moléculas de ligação, anticorpos humanizados, ácido nucleico isolado, célula hospedeira, métodos para produzir a molécula de ligação ao antígeno, para tratar um indivíduo e suprarregular ou prolongar a atividade de células t citotóxicas, composição farmacêutica e uso da molécula
|
JP7450647B2
(ja)
|
2019-06-26 |
2024-03-15 |
エフ. ホフマン-ラ ロシュ アーゲー |
Sirt-1遺伝子ノックアウトを有する哺乳類細胞株
|
CN114531878A
(zh)
|
2019-06-27 |
2022-05-24 |
豪夫迈·罗氏有限公司 |
新颖icos抗体及包含它们的肿瘤靶向抗原结合分子
|
MX2021015791A
(es)
|
2019-06-28 |
2022-04-01 |
Amgen Inc |
Proteínas de unión al antígeno biespecificas anti-receptor de cgrp/anti-receptor pac1.
|
WO2020264300A1
(en)
|
2019-06-28 |
2020-12-30 |
Genentech, Inc. |
Composition and methods for stabilizing liquid protein formulations
|
WO2021001289A1
(en)
|
2019-07-02 |
2021-01-07 |
F. Hoffmann-La Roche Ag |
Immunoconjugates comprising a mutant interleukin-2 and an anti-cd8 antibody
|
EP3994270A1
(en)
|
2019-07-02 |
2022-05-11 |
Fred Hutchinson Cancer Research Center |
Recombinant ad35 vectors and related gene therapy improvements
|
BR112021023173A2
(pt)
|
2019-07-10 |
2022-01-04 |
Chugai Pharmaceutical Co Ltd |
Moléculas de ligação à claudin-6 e usos das mesmas
|
WO2021005599A1
(en)
|
2019-07-11 |
2021-01-14 |
Kahr Medical Ltd. |
Heterodimers and methods of use thereof
|
AR119382A1
(es)
|
2019-07-12 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos de pre-direccionamiento y métodos de uso
|
AR119393A1
(es)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos que se unen a nkg2d
|
KR20220034857A
(ko)
|
2019-07-16 |
2022-03-18 |
사노피 |
알츠하이머병의 치료를 위한 중화 항-아밀로이드 베타 항체
|
US11634501B2
(en)
|
2019-07-19 |
2023-04-25 |
Oncoresponse, Inc. |
Immunomodulatory antibodies and methods of use thereof
|
EP4004037A1
(en)
|
2019-07-26 |
2022-06-01 |
Vanderbilt University |
Human monoclonal antibodies to enterovirus d68
|
BR112022001368A2
(pt)
|
2019-07-26 |
2022-05-24 |
Janssen Biotech Inc |
Proteínas que compreendem domínios de ligação ao antígeno de peptidase 2 relacionada à calicreína e seus usos
|
US20210023176A1
(en)
|
2019-07-26 |
2021-01-28 |
Genentech, Inc. |
DOSING FOR PREVENTION OR TREATMENT OF GRAFT VERSUS HOST DISEASE (GVHD) WITH IL-22 Fc FUSION PROTEINS
|
EP4004050A2
(en)
|
2019-07-30 |
2022-06-01 |
QLSF Biotherapeutics Inc. |
Multispecific binding compound that bind to lfrrc15 and cd3
|
EP4004045A1
(en)
|
2019-07-31 |
2022-06-01 |
F. Hoffmann-La Roche AG |
Antibodies binding to gprc5d
|
KR20220028035A
(ko)
|
2019-07-31 |
2022-03-08 |
에프. 호프만-라 로슈 아게 |
Gprc5d에 결합하는 항체
|
CN114341181A
(zh)
|
2019-07-31 |
2022-04-12 |
艾莱克特有限责任公司 |
抗ms4a4a抗体及其使用方法
|
AU2020319875A1
(en)
|
2019-08-01 |
2022-02-17 |
Incyte Corporation |
A dosing regimen for an IDO inhibitor
|
DE102019121007A1
(de)
|
2019-08-02 |
2021-02-04 |
Immatics Biotechnologies Gmbh |
Antigenbindende Proteine, die spezifisch an MAGE-A binden
|
US20210032370A1
(en)
|
2019-08-02 |
2021-02-04 |
Immatics Biotechnologies Gmbh |
Recruiting agent further binding an mhc molecule
|
JP7181438B2
(ja)
|
2019-08-06 |
2022-11-30 |
アプリノイア セラピューティクス リミテッド |
病理学的タウ種に結合する抗体及びその使用
|
WO2021026387A2
(en)
|
2019-08-06 |
2021-02-11 |
Xencor, Inc. |
HETERODIMERIC IgG-LIKE BISPECIFIC ANTIBODIES
|
MX2022001682A
(es)
|
2019-08-08 |
2022-05-13 |
Regeneron Pharma |
Nuevos formatos de moleculas de union a antigenos.
|
CN114867751A
(zh)
|
2019-08-12 |
2022-08-05 |
阿帕特夫研究和发展有限公司 |
4-1bb和ox40结合蛋白及相关组合物和方法、抗-4-1bb抗体、抗-ox40抗体
|
TW202120551A
(zh)
|
2019-08-12 |
2021-06-01 |
美商普瑞諾生物科技公司 |
藉由adcc靶向cd39表現細胞促進及增強t細胞介導免疫反應之方法及組合物
|
WO2021028752A1
(en)
|
2019-08-15 |
2021-02-18 |
Janssen Biotech, Inc. |
Anti-tfn antibodies for treating type i diabetes
|
AU2020328049A1
(en)
|
2019-08-15 |
2022-02-17 |
Janssen Biotech, Inc. |
Materials and methods for improved single chain variable fragments
|
WO2021035170A1
(en)
|
2019-08-21 |
2021-02-25 |
Precision Biosciences, Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
CN114650867A
(zh)
|
2019-08-30 |
2022-06-21 |
齐鲁普吉湾生物治疗公司 |
抗cd20抗体、抗cd37抗体及它们的混合物
|
GB201913079D0
(en)
|
2019-09-11 |
2019-10-23 |
Hummingbird Bioscience Holdings Pte Ltd |
Treatment and prevention of cancer using her3 antigen-binding molecules
|
CA3146616A1
(en)
|
2019-09-12 |
2021-03-18 |
Matthew Dominic CASCINO |
Compositions and methods of treating lupus nephritis
|
BR112022002351A2
(pt)
|
2019-09-16 |
2022-07-19 |
Surface Oncology Inc |
Composições e métodos de anticorpo anti-cd39
|
CA3150999A1
(en)
|
2019-09-18 |
2021-03-25 |
James Thomas Koerber |
Anti-klk7 antibodies, anti-klk5 antibodies, multispecific anti-klk5/klk7 antibodies, and methods of use
|
RU2753282C2
(ru)
|
2019-09-19 |
2021-08-12 |
Закрытое Акционерное Общество "Биокад" |
ИММУНОЦИТОКИН, ВКЛЮЧАЮЩИЙ ГЕТЕРОДИМЕРНЫЙ БЕЛКОВЫЙ КОМПЛЕКС НА ОСНОВЕ IL-15/IL-15Rα, И ЕГО ПРИМЕНЕНИЕ
|
CN114423454A
(zh)
|
2019-09-20 |
2022-04-29 |
豪夫迈·罗氏有限公司 |
抗类胰蛋白酶抗体的给药
|
MX2022003507A
(es)
|
2019-09-25 |
2022-04-25 |
Univ Stuttgart |
Modulos de union que comprenden dominios ehd2 modificados.
|
MX2022003719A
(es)
|
2019-09-25 |
2022-04-26 |
Surface Oncology Inc |
Anticuerpos anti-il-27 y sus usos.
|
US20220396635A1
(en)
|
2019-09-25 |
2022-12-15 |
Universität Stuttgart |
Trivalent binding molecules
|
US20220281997A1
(en)
|
2019-09-27 |
2022-09-08 |
Nanjing GenScript Biotech Co., Ltd. |
Anti-VHH Domain Antibodies and Use Thereof
|
WO2021057991A1
(zh)
|
2019-09-29 |
2021-04-01 |
北京加科思新药研发有限公司 |
对lif具有特异性的结合分子及其用途
|
EP4037700A2
(en)
|
2019-10-03 |
2022-08-10 |
Xencor, Inc. |
Targeted il-12 heterodimeric fc-fusion proteins
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
WO2021076489A1
(en)
*
|
2019-10-14 |
2021-04-22 |
Pierce Biotechnology, Inc. |
Peptide purification formulations and methods
|
CA3153880A1
(en)
|
2019-10-18 |
2020-06-09 |
Juana Elva HERNANDEZ MONTALVO |
Methods of using anti-cd79b immunoconjugates to treat diffuse large b-cell lymphoma
|
EP4048285A1
(en)
|
2019-10-21 |
2022-08-31 |
Novartis AG |
Tim-3 inhibitors and uses thereof
|
US20240301053A1
(en)
|
2019-10-21 |
2024-09-12 |
Novartis Ag |
Combination therapies with venetoclax and tim-3 inhibitors
|
WO2021084104A1
(en)
|
2019-10-30 |
2021-05-06 |
Bioinvent International Ab |
Tetravalent antibody molecules
|
CA3155308A1
(en)
|
2019-11-05 |
2021-05-14 |
F. Hoffmann-La Roche Ag |
Treatment of cancer using a hla-a2/wt1 x cd3 bispecific antibody and lenalidomide
|
CN114786730A
(zh)
|
2019-11-05 |
2022-07-22 |
再生元制药公司 |
N-端scFv多特异性结合分子
|
US20220389119A1
(en)
|
2019-11-08 |
2022-12-08 |
Amgen Inc. |
ENGINEERING CHARGE PAIR MUTATIONS FOR PAIRING OF HETERO-IgG MOLECULES
|
EP4058471A1
(en)
|
2019-11-14 |
2022-09-21 |
Werewolf Therapeutics, Inc. |
Activatable cytokine polypeptides and methods of use thereof
|
CA3161717A1
(en)
|
2019-11-15 |
2021-05-20 |
Dana LORD |
Biparatopic cd73 antibodies
|
BR112022008172A2
(pt)
|
2019-11-15 |
2022-07-12 |
Hoffmann La Roche |
Composição aquosa estável, método para obter uma composição e forma de dosagem farmacêutica
|
JP2023502652A
(ja)
|
2019-11-18 |
2023-01-25 |
ヤンセン バイオテツク,インコーポレーテツド |
抗cd79キメラ抗原受容体、car-t細胞、及びそれらの使用
|
JP2023501717A
(ja)
|
2019-11-19 |
2023-01-18 |
アムジエン・インコーポレーテツド |
新規の多重特異性抗体フォーマット
|
WO2021108661A2
(en)
|
2019-11-26 |
2021-06-03 |
Novartis Ag |
Chimeric antigen receptors and uses thereof
|
BR112022010096A2
(pt)
|
2019-12-06 |
2022-09-06 |
CSL Behring Lengnau AG |
Composições estáveis de multímeros fc
|
US20230035072A1
(en)
|
2019-12-12 |
2023-02-02 |
Alector Llc |
Methods of use of anti-cd33 antibodies
|
KR20220113790A
(ko)
|
2019-12-13 |
2022-08-16 |
제넨테크, 인크. |
항-ly6g6d 항체 및 사용 방법
|
TW202136287A
(zh)
|
2019-12-17 |
2021-10-01 |
法商Ose免疫治療公司 |
包含il-7變體之雙官能分子
|
CN115397853A
(zh)
|
2019-12-17 |
2022-11-25 |
辉瑞大药厂 |
对cd47、pd-l1具特异性的抗体及其用途
|
WO2021122875A1
(en)
|
2019-12-18 |
2021-06-24 |
F. Hoffmann-La Roche Ag |
Antibodies binding to hla-a2/mage-a4
|
CR20220277A
(es)
|
2019-12-18 |
2022-08-31 |
Hoffmann La Roche |
Anticuerpos anti-ccl2 biespecifico
|
GB201919062D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Antibody
|
GB201919061D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Multi-specific antibody
|
CN115175937A
(zh)
|
2019-12-20 |
2022-10-11 |
诺华股份有限公司 |
用于治疗骨髓纤维化和骨髓增生异常综合征的抗TIM-3抗体MBG453和抗TGF-β抗体NIS793与或不与地西他滨或抗PD-1抗体斯巴达珠单抗的组合
|
EP4077363A1
(en)
|
2019-12-20 |
2022-10-26 |
F. Hoffmann-La Roche AG |
Il-37 fusion proteins and uses thereof
|
TW202136316A
(zh)
|
2019-12-20 |
2021-10-01 |
美商再生元醫藥公司 |
新穎之il2促效劑及其使用方法(一)
|
CN115151567A
(zh)
|
2019-12-23 |
2022-10-04 |
索特里亚生物治疗药物公司 |
治疗性Fc组合物的化学诱导结合和解离以及T细胞接合器与人血清白蛋白的化学诱导二聚化
|
BR112022012439A2
(pt)
|
2019-12-23 |
2022-09-06 |
Genentech Inc |
Anticorpos isolados, ácido nucleico isolado, vetor isolado, célula hospedeira isolada e métodos para produzir um anticorpo que se liga à apol1, para detectar apolipoproteína l1 em uma amostra, para distinguir apolipoproteína l1 endógena, para distinguir as formas g0 e g1 de apolipoproteína l1 da forma apol1 g2 e para detectar especificamente células de podócitos
|
KR102645629B1
(ko)
|
2019-12-27 |
2024-03-07 |
추가이 세이야쿠 가부시키가이샤 |
항ctla-4 항체 및 그의 사용
|
CN114930170A
(zh)
|
2020-01-02 |
2022-08-19 |
豪夫迈·罗氏有限公司 |
用于测定脑中的治疗性抗体量的方法
|
BR112022013236A2
(pt)
|
2020-01-03 |
2022-09-06 |
Incyte Corp |
Anticorpos anti-cd73 e usos dos mesmos
|
WO2021138407A2
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
US12060433B2
(en)
|
2020-01-03 |
2024-08-13 |
Incyte Corporation |
CD73 inhibitor and A2A/A2B adenosine receptor inhibitor combination therapy
|
WO2021138512A1
(en)
|
2020-01-03 |
2021-07-08 |
Incyte Corporation |
Combination therapy comprising a2a/a2b and pd-1/pd-l1 inhibitors
|
JP2023509323A
(ja)
|
2020-01-06 |
2023-03-08 |
ヴァクシネックス, インコーポレイテッド |
抗ccr8抗体及びその使用
|
TW202140552A
(zh)
|
2020-01-08 |
2021-11-01 |
比利時商阿根思公司 |
用於治療天皰瘡病症的方法
|
EP4089111A4
(en)
|
2020-01-09 |
2023-10-04 |
Jiangsu Hengrui Medicine Co., Ltd. |
NEW POLYPEPTIDE COMPLEX
|
IL292780A
(en)
|
2020-01-09 |
2022-07-01 |
Hoffmann La Roche |
A new 4-1bbl trimer containing antigen-binding molecules
|
CN110818795B
(zh)
|
2020-01-10 |
2020-04-24 |
上海复宏汉霖生物技术股份有限公司 |
抗tigit抗体和使用方法
|
WO2021146487A2
(en)
|
2020-01-14 |
2021-07-22 |
Synthekine, Inc. |
Il2 orthologs and methods of use
|
CN114981284A
(zh)
|
2020-01-15 |
2022-08-30 |
豪夫迈·罗氏有限公司 |
减少来自重组蛋白生产过程中的杂质的方法
|
US20230132241A1
(en)
|
2020-01-15 |
2023-04-27 |
Immatics Biotechnologies Gmbh |
Antigen binding proteins specifically binding prame
|
WO2021146383A1
(en)
|
2020-01-17 |
2021-07-22 |
BioLegend, Inc. |
Anti-tlr7 agents and compositions and methods for making and using the same
|
CN114980902A
(zh)
|
2020-01-17 |
2022-08-30 |
诺华股份有限公司 |
用于治疗骨髓增生异常综合征或慢性粒单核细胞白血病的包含tim-3抑制剂和低甲基化药物的组合
|
EP4090762A1
(en)
|
2020-01-17 |
2022-11-23 |
Becton, Dickinson and Company |
Methods and compositions for single cell secretomics
|
BR112022014667A2
(pt)
|
2020-01-29 |
2022-09-20 |
Inhibrx Inc |
Anticorpos de domínio único de cd28 e construtos multivalentes e multiespecíficos dos mesmos
|
JP2023512071A
(ja)
|
2020-01-30 |
2023-03-23 |
ウモジャ バイオファーマ, インコーポレイテッド |
二特異性形質導入エンハンサー
|
GB202001447D0
(en)
|
2020-02-03 |
2020-03-18 |
Ucb Biopharma Sprl |
Antibodies
|
WO2021155916A1
(en)
|
2020-02-04 |
2021-08-12 |
BioNTech SE |
Treatment involving antigen vaccination and binding agents binding to pd-l1 and cd137
|
KR20220140568A
(ko)
|
2020-02-11 |
2022-10-18 |
벤더르빌트 유니버시티 |
중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)에 대한 인간 단일클론 항체
|
TW202144395A
(zh)
|
2020-02-12 |
2021-12-01 |
日商中外製藥股份有限公司 |
用於癌症之治療的抗cd137抗原結合分子
|
TW202144388A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在卵巢癌中表現之新抗原及其用途
|
EP4104187A1
(en)
|
2020-02-14 |
2022-12-21 |
Novartis AG |
Method of predicting response to chimeric antigen receptor therapy
|
TW202144389A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在多發性骨髓瘤中表現之新抗原及其用途
|
BR112022016550A2
(pt)
|
2020-02-21 |
2022-11-16 |
Harpoon Therapeutics Inc |
Proteínas de ligação a flt3 e métodos de uso
|
US20230174933A1
(en)
|
2020-02-27 |
2023-06-08 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
EP4110376A2
(en)
|
2020-02-27 |
2023-01-04 |
Novartis AG |
Methods of making chimeric antigen receptor-expressing cells
|
CA3169939A1
(en)
|
2020-02-28 |
2021-09-02 |
Jie Xue |
Anti-cd137 construct and use thereof
|
EP4110826A4
(en)
|
2020-02-28 |
2024-08-14 |
Shanghai Henlius Biotech Inc |
ANTI-CD137 CONSTRUCTS, MULTISPECIFIC ANTIBODIES AND THEIR USES
|
CN111269326A
(zh)
|
2020-02-28 |
2020-06-12 |
南京北恒生物科技有限公司 |
新型嵌合抗原受体及其用途
|
EP3875478A1
(en)
|
2020-03-05 |
2021-09-08 |
Canvax Biotech, S.L. |
Novel non-immunogenic chimeric antigen receptors and uses thereof
|
CA3174103A1
(en)
|
2020-03-06 |
2021-09-10 |
Go Therapeutics, Inc. |
Anti-glyco-cd44 antibodies and their uses
|
KR20230017165A
(ko)
|
2020-03-06 |
2023-02-03 |
인사이트 코포레이션 |
Axl/mer 및 pd-1/pd-l1 억제제를 포함하는 병행 요법
|
US11896619B2
(en)
|
2020-03-10 |
2024-02-13 |
Massachusetts Institute Of Technology |
Compositions and methods for immunotherapy of NPM1c-positive cancer
|
CR20220461A
(es)
|
2020-03-13 |
2022-10-21 |
Genentech Inc |
Anticuerpos anti-interleucina-33 y usos de estos
|
EP4233893A3
(en)
|
2020-03-13 |
2023-09-27 |
Janssen Biotech, Inc. |
Materials and methods for binding siglec-3/cd33
|
BR112022015572A2
(pt)
|
2020-03-18 |
2022-09-27 |
Genmab As |
Anticorpo, composição, composição farmacêutica, anticorpo para uso como um medicamento, métodos para tratar uma doença e para produzir um anticorpo, ácido nucléico, um ou mais ácidos nucléicos, célula, e, kit de partes
|
EP4121163A1
(en)
|
2020-03-19 |
2023-01-25 |
Genentech, Inc. |
Isoform-selective anti-tgf-beta antibodies and methods of use
|
US11365239B2
(en)
|
2020-03-20 |
2022-06-21 |
Tsb Therapeutics (Beijing) Co., Ltd. |
Anti-SARS-COV-2 antibodies and uses thereof
|
WO2021190980A1
(en)
|
2020-03-22 |
2021-09-30 |
Quadrucept Bio Limited |
Multimers for viral strain evolution
|
WO2021194913A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Tie2-binding agents and methods of use
|
WO2021195385A1
(en)
|
2020-03-26 |
2021-09-30 |
Vanderbilt University |
HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-GoV-2)
|
KR20220159426A
(ko)
|
2020-03-26 |
2022-12-02 |
제넨테크, 인크. |
감소된 숙주 세포 단백질을 보유하는 변형된 포유동물 세포
|
PT4045533T
(pt)
|
2020-03-26 |
2024-02-14 |
Univ Vanderbilt |
Anticorpos monoclonais humanos para síndrome respiratória aguda grave coronavírus 2 (sars-cov-2)
|
JP2023520773A
(ja)
|
2020-03-27 |
2023-05-19 |
ノバルティス アーゲー |
増殖性疾患及び自己免疫疾患を治療するための二重特異性組合せ治療
|
TW202204407A
(zh)
|
2020-03-30 |
2022-02-01 |
國立大學法人三重大學 |
雙特異性抗體
|
CA3173519A1
(en)
|
2020-03-31 |
2021-10-07 |
Vishnu Priyanka Reddy CHICHILI |
Method for producing multispecific antigen-binding molecules
|
AR121706A1
(es)
|
2020-04-01 |
2022-06-29 |
Hoffmann La Roche |
Moléculas de unión a antígeno biespecíficas dirigidas a ox40 y fap
|
US20240183826A9
(en)
|
2020-04-02 |
2024-06-06 |
Chugai Seiyaku Kabushiki Kaisha |
Analysis method for impurity molecules in composition containing multi-specific antigen-binding molecules
|
WO2021202959A1
(en)
|
2020-04-03 |
2021-10-07 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
KR20220167295A
(ko)
|
2020-04-10 |
2022-12-20 |
싸이톰스 테라퓨틱스, 인크. |
활성화가능한 사이토카인 작제물과 관련된 조성물 및 방법
|
WO2021207662A1
(en)
|
2020-04-10 |
2021-10-14 |
Genentech, Inc. |
Use of il-22fc for the treatment or prevention of pneumonia, acute respiratory distress syndrome, or cytokine release syndrome
|
CN116249712A
(zh)
|
2020-04-15 |
2023-06-09 |
沃雅戈治疗公司 |
Tau结合化合物
|
BR112022020629A2
(pt)
|
2020-04-15 |
2022-11-29 |
Hoffmann La Roche |
Polipeptídeo de interleucina-7 (il-7) mutante, imunoconjugado, um ou mais polinucleotídeos isolados, célula hospedeira, métodos para produzir um polipeptídeo il-7 mutante ou um imunoconjugado, para tratar uma doença e para estimular o sistema imunológico, polipeptídeo il-7 mutante, composição farmacêutica, uso do polipeptídeo il-7 mutante e invenção
|
GB202005879D0
(en)
|
2020-04-22 |
2020-06-03 |
Petmedix Ltd |
Heterodimeric proteins
|
JP2023522972A
(ja)
|
2020-04-22 |
2023-06-01 |
ドラゴンフライ セラピューティクス, インコーポレイテッド |
ヘテロ二量体Fc融合タンパク質のための製剤、投薬量レジメン、及び製造工程
|
CA3180321A1
(en)
|
2020-04-24 |
2021-10-28 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to t cell related cancer cells and uses thereof
|
US20230265204A1
(en)
|
2020-04-24 |
2023-08-24 |
Hoffmann-La Roche Inc. |
Enzyme and pathway modulation with sulfhydryl compounds and their derivatives
|
WO2021217051A1
(en)
|
2020-04-24 |
2021-10-28 |
Genentech, Inc. |
Methods of using anti-cd79b immunoconjugates
|
CN115803344A
(zh)
|
2020-04-26 |
2023-03-14 |
百奥赛图(北京)医药科技股份有限公司 |
经修饰的免疫球蛋白
|
WO2021222167A1
(en)
|
2020-04-28 |
2021-11-04 |
Genentech, Inc. |
Methods and compositions for non-small cell lung cancer immunotherapy
|
US11634477B2
(en)
|
2020-04-28 |
2023-04-25 |
The Rockefeller University |
Neutralizing anti-SARS-CoV-2 antibodies and methods of use thereof
|
TWI838621B
(zh)
|
2020-04-29 |
2024-04-11 |
美商泰尼歐萬公司 |
具有經修飾重鏈恆定區之多特異性重鏈抗體
|
EP4186564A1
(en)
|
2020-04-29 |
2023-05-31 |
Teneoone, Inc. |
Multispecific heavy chain antibodies with modified heavy chain constant regions
|
AU2021263408A1
(en)
|
2020-04-30 |
2022-10-27 |
Bristol-Myers Squibb Company |
Methods of treating cytokine-related adverse events
|
WO2021222533A1
(en)
|
2020-04-30 |
2021-11-04 |
Procisedx Inc. |
Methods of detecting antibodies to sars-cov-2
|
EP4143236A1
(en)
|
2020-05-01 |
2023-03-08 |
Novartis AG |
Engineered immunoglobulins
|
CN116963782A
(zh)
|
2020-05-03 |
2023-10-27 |
联宁(苏州)生物制药有限公司 |
包含抗trop-2抗体的抗体药物偶联物
|
PE20230494A1
(es)
|
2020-05-08 |
2023-03-23 |
Alpine Immune Sciences Inc |
Proteinas inmunomoduladoras inhibidoras de april y baff y metodos de uso de las mismas
|
CR20220576A
(es)
|
2020-05-11 |
2022-12-07 |
Hoffmann La Roche |
Tratamiento conjunto con pbmc modificadas y un inmunoconjugado
|
MX2022014203A
(es)
|
2020-05-12 |
2023-02-22 |
Lyell Immunopharma Inc |
Espaciadores de receptores de antígenos quiméricos (car).
|
KR20230009430A
(ko)
|
2020-05-12 |
2023-01-17 |
리제너론 파아마슈티컬스, 인크. |
신규 il10 효능제 및 그의 사용 방법
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
WO2021231969A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind msln and cd3
|
EP4149421A1
(en)
|
2020-05-15 |
2023-03-22 |
F. Hoffmann-La Roche AG |
Prevention of visible particle formation in parenteral protein solutions
|
EP4149964A2
(en)
|
2020-05-15 |
2023-03-22 |
Apogenix AG |
Multi-specific immune modulators
|
JP2023504675A
(ja)
|
2020-05-19 |
2023-02-06 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ガンの処置のための結合分子
|
CN115605185A
(zh)
|
2020-05-19 |
2023-01-13 |
豪夫迈·罗氏有限公司(Ch) |
螯合剂用于防止胃肠外蛋白质溶液中形成可见颗粒的用途
|
PE20230389A1
(es)
|
2020-05-27 |
2023-03-06 |
Janssen Biotech Inc |
Proteinas que comprenden dominios de union al antigeno de cd3 y usos de estas
|
CN111849910B
(zh)
|
2020-05-27 |
2021-06-15 |
南京北恒生物科技有限公司 |
工程化免疫细胞及其用途
|
BR112022024339A2
(pt)
|
2020-05-29 |
2022-12-27 |
23Andme Inc |
Anticorpos anti cd200r1 e métodos de uso dos mesmos
|
CN115698086A
(zh)
|
2020-06-01 |
2023-02-03 |
马斯得生物有限公司 |
一种双特异性抗体或其抗原结合片段及其制备方法
|
KR20230018439A
(ko)
|
2020-06-02 |
2023-02-07 |
바이오사이토젠 파마슈티컬스 (베이징) 컴퍼니 리미티드 |
공동 경쇄 면역글로불린 좌위를 갖는 유전자 변형 비인간 동물
|
CN115697489A
(zh)
|
2020-06-08 |
2023-02-03 |
豪夫迈·罗氏有限公司 |
抗hbv抗体及其使用方法
|
KR20220166837A
(ko)
|
2020-06-11 |
2022-12-19 |
난징 바이오흐엥 바이오테크 씨오., 엘티디 |
Nk억제 분자를 발현하는 조작된 면역 세포 및 그 용도
|
EP4165169A1
(en)
|
2020-06-11 |
2023-04-19 |
Novartis AG |
Zbtb32 inhibitors and uses thereof
|
JP2023529206A
(ja)
|
2020-06-12 |
2023-07-07 |
ジェネンテック, インコーポレイテッド |
がん免疫療法のための方法及び組成物
|
KR20230025691A
(ko)
|
2020-06-16 |
2023-02-22 |
제넨테크, 인크. |
삼중 음성 유방암을 치료하기 위한 방법과 조성물
|
CA3176552A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Immune activating fc domain binding molecules
|
TW202214286A
(zh)
|
2020-06-19 |
2022-04-16 |
日商中外製藥股份有限公司 |
用於與血管新生抑制劑組合使用之抗t細胞抗原結合分子
|
AU2021291002A1
(en)
|
2020-06-19 |
2022-10-13 |
F. Hoffmann-La Roche Ag |
Protease-activated T cell bispecific antibodies
|
EP4168447A1
(en)
|
2020-06-19 |
2023-04-26 |
F. Hoffmann-La Roche AG |
Antibodies binding to cd3 and cd19
|
WO2021255142A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3
|
WO2021255146A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and cea
|
CR20220639A
(es)
|
2020-06-19 |
2023-02-17 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y folr1
|
WO2021259880A1
(en)
|
2020-06-22 |
2021-12-30 |
Almirall, S.A. |
Anti-il-36 antibodies and methods of use thereof
|
JP2023530760A
(ja)
|
2020-06-23 |
2023-07-19 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Her2を標的とするアゴニストCD28抗原結合分子
|
KR20230027056A
(ko)
|
2020-06-23 |
2023-02-27 |
노파르티스 아게 |
3-(1-옥소이소인돌린-2-일)피페리딘-2,6-디온 유도체를 포함하는 투약 요법
|
KR20230026491A
(ko)
|
2020-06-24 |
2023-02-24 |
제넨테크, 인크. |
아폽토시스 내성 세포주
|
EP4172203A1
(en)
|
2020-06-25 |
2023-05-03 |
F. Hoffmann-La Roche AG |
Anti-cd3/anti-cd28 bispecific antigen binding molecules
|
EP4171614A1
(en)
|
2020-06-29 |
2023-05-03 |
Resolve Therapeutics, LLC |
Treatment of sjogren's syndrome with nuclease fusion proteins
|
WO2022006219A2
(en)
|
2020-07-02 |
2022-01-06 |
Trustees Of Tufts College |
Vhh polypeptides that bind to clostridium difficile toxin b and methods of use thereof
|
EP4178529A1
(en)
|
2020-07-07 |
2023-05-17 |
F. Hoffmann-La Roche AG |
Alternative surfactants as stabilizers for therapeutic protein formulations
|
EP4178985A1
(en)
|
2020-07-10 |
2023-05-17 |
F. Hoffmann-La Roche AG |
Antibodies which bind to cancer cells and target radionuclides to said cells
|
JP2023527530A
(ja)
|
2020-07-15 |
2023-06-29 |
南京北恒生物科技有限公司 |
同種異系移植のための操作された免疫細胞
|
JP2023534214A
(ja)
|
2020-07-16 |
2023-08-08 |
ノバルティス アーゲー |
抗ベータセルリン抗体、その断片、及び多重特異性結合分子
|
WO2022016119A1
(en)
|
2020-07-17 |
2022-01-20 |
Simurx, Inc. |
Chimeric myd88 receptors for redirecting immunosuppressive signaling and related compositions and methods
|
MX2023000617A
(es)
|
2020-07-17 |
2023-02-13 |
Genentech Inc |
Anticuerpos anti-notch2 y metodos de uso.
|
AR123019A1
(es)
|
2020-07-21 |
2022-10-26 |
Genentech Inc |
Inductores químicos de degradación conjugados con anticuerpo de brm y métodos de estos
|
WO2022018178A1
(en)
|
2020-07-24 |
2022-01-27 |
F. Hoffmann-La Roche Ag |
Method for the expression of an antibody-multimer-fusion
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
BR112023001500A2
(pt)
|
2020-07-29 |
2023-04-11 |
Janssen Biotech Inc |
Proteínas que compreendem domínios de ligação ao antígeno hla-g e usos dos mesmos
|
CN114057890A
(zh)
|
2020-07-31 |
2022-02-18 |
南京北恒生物科技有限公司 |
新型共刺激结构域及其用途
|
MX2023001120A
(es)
|
2020-07-31 |
2023-02-22 |
Chugai Pharmaceutical Co Ltd |
Composicion farmaceutica que comprende una celula que expresa un receptor quimerico.
|
JP2023536164A
(ja)
|
2020-08-03 |
2023-08-23 |
ノバルティス アーゲー |
ヘテロアリール置換3-(1-オキソイソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体及びその使用
|
EP4192863A2
(en)
|
2020-08-05 |
2023-06-14 |
Synthekine, Inc. |
Il2rg binding molecules and methods of use
|
US20230295314A1
(en)
|
2020-08-05 |
2023-09-21 |
Synthekine, Inc. |
IL27RAlpha Binding Molecules and Methods of Use
|
US20230272090A1
(en)
|
2020-08-05 |
2023-08-31 |
Sandro Vivona |
Il2rb binding molecules and methods of use
|
CA3190486A1
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il10 receptor binding molecules and methods of use
|
WO2022032040A1
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il2rb/il2rg synthetic cytokines
|
WO2022055641A2
(en)
|
2020-08-05 |
2022-03-17 |
Synthekine, Inc. |
Compositions and methods related to receptor pairings
|
AU2021320327A1
(en)
|
2020-08-05 |
2023-03-23 |
Synthekine, Inc. |
IL10Rb binding molecules and methods of use
|
KR20230061394A
(ko)
|
2020-08-05 |
2023-05-08 |
신테카인, 인크. |
IL10Ra 결합 분자 및 사용 방법
|
CN116723859A
(zh)
|
2020-08-05 |
2023-09-08 |
辛德凯因股份有限公司 |
IL27Rα结合分子及使用方法
|
AU2021320226A1
(en)
|
2020-08-05 |
2023-03-23 |
Synthekine, Inc. |
gp130 binding molecules and methods of use
|
CN116194477A
(zh)
|
2020-08-06 |
2023-05-30 |
生物技术欧洲股份公司 |
冠状病毒s蛋白的结合剂
|
CN112063588A
(zh)
|
2020-08-13 |
2020-12-11 |
南京北恒生物科技有限公司 |
工程化免疫细胞及其用途
|
KR102607909B1
(ko)
|
2020-08-19 |
2023-12-01 |
젠코어 인코포레이티드 |
항-cd28 조성물
|
MX2023002107A
(es)
|
2020-08-21 |
2023-03-15 |
Novartis Ag |
Composiciones y metodos para la generacion in vivo de celulas que expresan car.
|
EP4204458A1
(en)
|
2020-08-26 |
2023-07-05 |
Marengo Therapeutics, Inc. |
Methods of detecting trbc1 or trbc2
|
CN116249718A
(zh)
|
2020-08-26 |
2023-06-09 |
马伦戈治疗公司 |
结合至钙网蛋白的多功能性分子及其用途
|
KR20230074144A
(ko)
|
2020-08-26 |
2023-05-26 |
마렝고 테라퓨틱스, 인크. |
NKp30에 결합하는 항체 분자 및 이의 용도
|
WO2022047222A2
(en)
|
2020-08-28 |
2022-03-03 |
Genentech, Inc. |
Crispr/cas9 multiplex knockout of host cell proteins
|
WO2022044248A1
(ja)
|
2020-08-28 |
2022-03-03 |
中外製薬株式会社 |
ヘテロ二量体Fcポリペプチド
|
EP4204020A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
WO2022043557A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
JP2023539528A
(ja)
|
2020-09-01 |
2023-09-14 |
メルック・パテント・ゲーエムベーハー |
Nkp30結合体
|
WO2022050401A2
(en)
|
2020-09-01 |
2022-03-10 |
Takeda Pharmaceutical Company Limited |
Interleukin-2 muteins and uses thereof
|
CN114163532A
(zh)
|
2020-09-10 |
2022-03-11 |
南京北恒生物科技有限公司 |
包含新型共刺激结构域的嵌合抗原受体及其用途
|
BR112023004327A2
(pt)
|
2020-09-10 |
2023-04-04 |
Genmab As |
Método para tratar leucemia linfocítica crônica em um sujeito humano
|
AU2021340232A1
(en)
|
2020-09-10 |
2023-04-13 |
Genmab A/S |
Bispecific antibody against CD3 and CD20 in combination therapy for treating diffuse large B-cell lymphoma
|
KR20230066386A
(ko)
|
2020-09-11 |
2023-05-15 |
리제너론 파마슈티칼스 인코포레이티드 |
항원 특이적 항체의 확인 및 제조
|
CN116670164A
(zh)
|
2020-09-14 |
2023-08-29 |
苏特罗生物制药公司 |
使用无细胞蛋白质合成系统大规模生产抗体的方法
|
EP4214244A1
(en)
|
2020-09-21 |
2023-07-26 |
Genentech, Inc. |
Purification of multispecific antibodies
|
MX2023003328A
(es)
|
2020-09-24 |
2023-03-27 |
Hoffmann La Roche |
Lineas de celulas de mamifero con desactivacion genica.
|
AU2021350075A1
(en)
|
2020-09-24 |
2023-03-09 |
F. Hoffmann-La Roche Ag |
Prevention or mitigation of T-cell bispecific antibody-related adverse effects
|
TW202216784A
(zh)
|
2020-09-29 |
2022-05-01 |
大陸商信達生物製藥(蘇州)有限公司 |
抗cd3抗體以及其用途
|
KR20230082632A
(ko)
|
2020-10-05 |
2023-06-08 |
제넨테크, 인크. |
항-fcrh5/항-cd3 이중특이성 항체를 사용한 치료를 위한 투약
|
US12037399B2
(en)
|
2020-10-07 |
2024-07-16 |
Dren Bio, Inc. |
Anti-Dectin-1 antibodies and methods of use thereof
|
AU2021357841A1
(en)
|
2020-10-08 |
2023-06-15 |
Affimed Gmbh |
Trispecific binders
|
US12006550B2
(en)
|
2020-10-12 |
2024-06-11 |
University Of South Carolina |
Targeting treatment for ADAM30 in pathological cells
|
KR20230086765A
(ko)
|
2020-10-13 |
2023-06-15 |
얀센 바이오테크 인코포레이티드 |
분화 클러스터 iv 및/또는 viii을 조절하기 위한 바이오-조작된 t 세포 매개 면역, 물질 및 기타 방법
|
US20220135684A1
(en)
|
2020-10-14 |
2022-05-05 |
Xencor, Inc. |
Bispecific antibodies that bind pd-l1 and cd28
|
AU2021362007A1
(en)
|
2020-10-16 |
2023-06-22 |
Invisishield Technologies Ltd. |
Compositions for preventing or treating viral and other microbial infections
|
US20240084014A1
(en)
|
2020-10-16 |
2024-03-14 |
Qlsf Biotherapeutics, Inc. |
Multispecific binding compounds that bind to pd-l1
|
AR123855A1
(es)
|
2020-10-20 |
2023-01-18 |
Genentech Inc |
Anticuerpos anti-mertk conjugados con peg y métodos de uso
|
WO2022084210A1
(en)
|
2020-10-20 |
2022-04-28 |
F. Hoffmann-La Roche Ag |
Combination therapy of pd-1 axis binding antagonists and lrrk2 inhitibors
|
IL302277A
(en)
|
2020-10-22 |
2023-06-01 |
Janssen Biotech Inc |
Proteins containing delta-like ligand antigen binding domains (DLL3) and uses thereof
|
WO2022087458A1
(en)
|
2020-10-23 |
2022-04-28 |
Asher Biotherapeutics, Inc. |
Fusions with cd8 antigen binding molecules for modulating immune cell function
|
JP2023549062A
(ja)
|
2020-10-30 |
2023-11-22 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
CEA CD3二重特異性抗体及びTGFβシグナル伝達阻害剤を使用したがんの治療
|
WO2022093641A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2a agents and compositions and methods for making and using the same
|
WO2022093640A1
(en)
|
2020-10-30 |
2022-05-05 |
BioLegend, Inc. |
Anti-nkg2c agents and compositions and methods for making and using the same
|
EP4237451A1
(en)
|
2020-11-02 |
2023-09-06 |
Hummingbird Bioscience Pte. Ltd. |
Bcma/taci antigen-binding molecules
|
CN114525259A
(zh)
|
2020-11-03 |
2022-05-24 |
南京北恒生物科技有限公司 |
靶向cd7的嵌合抗原受体及其用途
|
CN112300282A
(zh)
|
2020-11-03 |
2021-02-02 |
南京北恒生物科技有限公司 |
靶向cd7的人源化抗体及其用途
|
EP4240758A1
(en)
|
2020-11-04 |
2023-09-13 |
The Rockefeller University |
Neutralizing anti-sars-cov-2 antibodies
|
WO2022097090A1
(en)
|
2020-11-05 |
2022-05-12 |
Novartis Ag |
Dosing regimen for combination therapies with multispecific antibodies targeting b-cell maturation antigen and gamma secretase inhibitors
|
JP2023551113A
(ja)
|
2020-11-06 |
2023-12-07 |
バイオ-テラ ソリュ-ションズ,エルティーディー. |
二重特異性抗体及びその応用
|
US20240002509A1
(en)
|
2020-11-06 |
2024-01-04 |
Novartis Ag |
ANTIBODY Fc VARIANTS
|
WO2022099090A1
(en)
|
2020-11-06 |
2022-05-12 |
Xencor, Inc. |
Heterodimeric antibodies that bind tgfbrii
|
MX2023005234A
(es)
|
2020-11-06 |
2023-05-18 |
Novartis Ag |
Terapia de combinacion de agente anti-cd19 y agente de direccionamiento a celulas b para el tratamiento de neoplasias malignas de celulas b.
|
CA3199095A1
(en)
|
2020-11-06 |
2022-05-12 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
WO2022101120A1
(en)
|
2020-11-10 |
2022-05-19 |
F. Hoffmann-La Roche Ag |
Prevention or mitigation of t-cell engaging agent-related adverse effects
|
CN117120477A
(zh)
|
2020-11-10 |
2023-11-24 |
上海齐鲁制药研究中心有限公司 |
针对密蛋白18a2和cd3的双特异性抗体及其应用
|
JP2023549504A
(ja)
|
2020-11-13 |
2023-11-27 |
ノバルティス アーゲー |
キメラ抗原受容体(car)発現細胞との組合せ療法
|
CN117916261A
(zh)
|
2020-11-16 |
2024-04-19 |
豪夫迈·罗氏有限公司 |
与靶向fap的cd40激动剂的组合疗法
|
CR20230253A
(es)
|
2020-11-16 |
2023-07-26 |
Hoffmann La Roche |
Glucoformas de fab ricas en manosa
|
CN114524876A
(zh)
|
2020-11-23 |
2022-05-24 |
南京北恒生物科技有限公司 |
靶向nkg2a的抗体及其用途
|
WO2022115762A1
(en)
|
2020-11-30 |
2022-06-02 |
Incyte Corporation |
Combination therapy with an anti-cd19 antibody and parsaclisib
|
WO2022115120A1
(en)
|
2020-11-30 |
2022-06-02 |
Incyte Corporation |
Combination therapy with an anti-cd19 antibody and parsaclisib
|
MX2023006426A
(es)
|
2020-12-01 |
2023-07-17 |
Aptevo Res & Development Llc |
Antígenos asociados a tumores y proteínas de unión a cd3 y composiciones y métodos relacionados.
|
CA3202986A1
(en)
|
2020-12-02 |
2022-06-09 |
Alector Llc |
Methods of use of anti-sortilin antibodies
|
MX2023006480A
(es)
|
2020-12-04 |
2023-06-19 |
Hoffmann La Roche |
Polipeptidos de interleucina-2 mutante dependientes del ph.
|
AU2021395729A1
(en)
|
2020-12-07 |
2023-07-13 |
UCB Biopharma SRL |
Multi-specific antibodies and antibody combinations
|
WO2022122652A1
(en)
|
2020-12-07 |
2022-06-16 |
UCB Biopharma SRL |
Antibodies against interleukin-22
|
KR20230120665A
(ko)
|
2020-12-17 |
2023-08-17 |
에프. 호프만-라 로슈 아게 |
항-hla-g 항체 및 이의 용도
|
EP4263606A1
(en)
|
2020-12-17 |
2023-10-25 |
Ose Immunotherapeutics |
Bifunctional anti-pd1/il-7 molecules
|
CN116601175A
(zh)
|
2020-12-18 |
2023-08-15 |
豪夫迈·罗氏有限公司 |
用于靶向疗法的前体蛋白和试剂盒
|
JP2024501662A
(ja)
|
2020-12-22 |
2024-01-15 |
エフ. ホフマン-ラ ロシュ アーゲー |
Xbp1を標的とするオリゴヌクレオチド
|
US20220195014A1
(en)
|
2020-12-23 |
2022-06-23 |
Regeneron Pharmaceuticals, Inc. |
Nucleic acids encoding anchor modified antibodies and uses thereof
|
US20220227867A1
(en)
|
2020-12-24 |
2022-07-21 |
Xencor, Inc. |
ICOS TARGETED HETERODIMERIC FUSION PROTEINS CONTAINING IL-15/IL-15RA Fc-FUSION PROTEINS AND ICOS ANTIGEN BINDING DOMAINS
|
US20220233529A1
(en)
|
2020-12-29 |
2022-07-28 |
Incyte Corporation |
Combination therapy comprising a2a/a2b inhibitors, pd-1/pd-l1 inhibitors, and anti-cd73 antibodies
|
CA3207090A1
(en)
|
2021-01-06 |
2022-07-14 |
F. Hoffmann-La Roche Ag |
Combination therapy employing a pd1-lag3 bispecific antibody and a cd20 t cell bispecific antibody
|
WO2022148853A1
(en)
|
2021-01-11 |
2022-07-14 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
EP4274616A2
(en)
|
2021-01-11 |
2023-11-15 |
Synthekine, Inc. |
Compositions and methods related to receptor pairing
|
JP2024502129A
(ja)
|
2021-01-12 |
2024-01-17 |
エスジー メディカル インコーポレイテッド |
Cd55に対する新規抗体及びその用途
|
US20240052029A1
(en)
|
2021-01-12 |
2024-02-15 |
Bioheng Therapeutics Limited |
Ror1-targeting antibody and use thereof
|
AU2022207615A1
(en)
|
2021-01-12 |
2023-07-13 |
F. Hoffmann-La Roche Ag |
Split antibodies which bind to cancer cells and target radionuclides to said cells
|
JP2024503654A
(ja)
|
2021-01-13 |
2024-01-26 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
併用療法
|
US20240076346A1
(en)
*
|
2021-01-13 |
2024-03-07 |
Kahr Medical Ltd. |
Type i membrane proteins heterodimers and methods of use thereof
|
JP2024505636A
(ja)
|
2021-01-15 |
2024-02-07 |
ザ ロックフェラー ユニバーシティー |
抗sars-cov-2中和抗体
|
TW202244060A
(zh)
|
2021-01-20 |
2022-11-16 |
美商昂科里斯龐司公司 |
免疫調節抗體及其用途
|
CN116917326A
(zh)
|
2021-01-22 |
2023-10-20 |
博泰康医药公司 |
抗her-2/trop-2构建体及其用途
|
WO2022162587A1
(en)
|
2021-01-27 |
2022-08-04 |
Centre Hospitalier Universitaire Vaudois (C.H.U.V.) |
Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
|
WO2022162569A1
(en)
|
2021-01-29 |
2022-08-04 |
Novartis Ag |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
WO2022169872A1
(en)
|
2021-02-03 |
2022-08-11 |
Genentech, Inc. |
Multispecific binding protein degrader platform and methods of use
|
MX2023009100A
(es)
|
2021-02-03 |
2023-09-25 |
Mozart Therapeutics Inc |
Agentes aglutinantes y métodos para usar los mismos.
|
EP4273175A4
(en)
|
2021-02-03 |
2024-08-14 |
Bioheng Therapeutics Ltd |
NOVEL CHIMERIC ANTIGEN RECEPTOR AND ITS USE
|
CA3206844A1
(en)
|
2021-02-05 |
2022-08-11 |
John Li |
Il-15 fusion proteins and methods of making and using same
|
JP2024506694A
(ja)
|
2021-02-16 |
2024-02-14 |
ヤンセン バイオテツク,インコーポレーテツド |
増強されたリンカー標的化のための材料及び方法
|
JP2024512240A
(ja)
|
2021-02-18 |
2024-03-19 |
エフ. ホフマン-ラ ロシュ アーゲー |
複雑な多段階の抗体相互作用を解明するための方法
|
WO2022177393A1
(ko)
|
2021-02-19 |
2022-08-25 |
(주)샤페론 |
Pd-l1에 대한 단일 도메인 항체 및 이의 용도
|
CN116964095A
(zh)
|
2021-02-19 |
2023-10-27 |
沙裴隆有限公司 |
针对cd47的单域抗体及其用途
|
AU2022227686A1
(en)
|
2021-02-25 |
2023-07-27 |
Lyell Immunopharma, Inc. |
Ror1 targeting chimeric antigen receptor
|
WO2022184659A1
(en)
|
2021-03-01 |
2022-09-09 |
Quadrucept Bio Limited |
Antibody domains & multimers
|
JP2024509169A
(ja)
|
2021-03-03 |
2024-02-29 |
ソレント・セラピューティクス・インコーポレイテッド |
抗bcma抗体を含む抗体-薬物コンジュゲート
|
WO2022187591A1
(en)
|
2021-03-05 |
2022-09-09 |
Go Therapeutics, Inc. |
Anti-glyco-cd44 antibodies and their uses
|
WO2022192259A1
(en)
|
2021-03-09 |
2022-09-15 |
Cureimmune Therapeutics Inc. |
BIFUNCTIONAL HOMODIMERIC ANTI-PD-1 AND IL-15/IL-15Rα FUSION PROTEINS AND USES THEREOF
|
WO2022189380A1
(en)
|
2021-03-09 |
2022-09-15 |
F. Hoffmann-La Roche Ag |
Combination therapy of pd-1-targeted il-2 variant immunoconjugate and anti-tyrp1/anti-cd3 bispecific antibodies
|
AU2022232375A1
(en)
|
2021-03-09 |
2023-09-21 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cldn6
|
KR20230156051A
(ko)
|
2021-03-09 |
2023-11-13 |
에프. 호프만-라 로슈 아게 |
Pd-1-표적화 il-2 변이체 면역접합체 및 fap/4-1bb 결합 분자의 병용 요법
|
EP4305065A1
(en)
|
2021-03-10 |
2024-01-17 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and gpc3
|
JP2024512377A
(ja)
|
2021-03-12 |
2024-03-19 |
ジェネンテック, インコーポレイテッド |
抗klk7抗体、抗klk5抗体、多重特異性抗klk5/klk7抗体、及び使用方法
|
KR20230156387A
(ko)
|
2021-03-12 |
2023-11-14 |
얀센 바이오테크 인코포레이티드 |
항-il23 특이적 항체에 의해 건선성 관절염을 치료하는 안전하고 효과적인 방법
|
MX2023010697A
(es)
|
2021-03-12 |
2023-11-23 |
Janssen Biotech Inc |
Método para tratar pacientes con artritis psoriásica con respuesta inadecuada a la terapia de tnf con anticuerpo específico anti-il23.
|
BR112023018621A2
(pt)
|
2021-03-15 |
2023-10-24 |
Hoffmann La Roche |
Métodos para tratar nefrite lúpica, esgotar células b periféricas, kits para tratar nefrite lúpica e anticorpos anti-cd20 tipo ii
|
KR20230157448A
(ko)
|
2021-03-16 |
2023-11-16 |
싸이톰스 테라퓨틱스, 인크. |
마스킹된 활성화 가능한 사이토카인 작제물 및 관련 조성물 및 방법
|
WO2022197947A1
(en)
|
2021-03-18 |
2022-09-22 |
Alector Llc |
Anti-tmem106b antibodies and methods of use thereof
|
WO2022197877A1
(en)
|
2021-03-19 |
2022-09-22 |
Genentech, Inc. |
Methods and compositions for time delayed bio-orthogonal release of cytotoxic agents
|
US20220315655A1
(en)
|
2021-03-22 |
2022-10-06 |
Novimmune Sa |
Bispecific antibodies targeting cd47 and pd-l1 and methods of use thereof
|
CA3212599A1
(en)
|
2021-03-22 |
2022-09-29 |
Novimmune S.A. |
Bispecific antibodies targeting cd47 and pd-l1 and methods of use thereof
|
EP4314063A1
(en)
|
2021-03-23 |
2024-02-07 |
Alector LLC |
Anti-tmem106b antibodies for treating and preventing coronavirus infections
|
BR112023019458A2
(pt)
|
2021-03-24 |
2023-12-05 |
Janssen Biotech Inc |
Proteínas que compreendem domínios de ligação ao antígeno de cd3 e usos dos mesmos
|
JP2024512035A
(ja)
|
2021-03-24 |
2024-03-18 |
ヤンセン バイオテツク,インコーポレーテツド |
Cd22及びcd79bを標的とする抗体
|
MX2023011340A
(es)
|
2021-03-26 |
2023-12-14 |
Janssen Biotech Inc |
Anticuerpos humanizados contra el filamento helicoidal emparejado tau y usos de estos.
|
WO2022210485A1
(ja)
|
2021-03-29 |
2022-10-06 |
第一三共株式会社 |
安定な多重特異性分子及びその利用
|
WO2022207615A1
(en)
|
2021-03-31 |
2022-10-06 |
F. Hoffmann-La Roche Ag |
Purification of antibodies by mixed mode chromatography
|
CA3237992A1
(en)
|
2021-03-31 |
2022-10-06 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Truncated taci polypeptide and fusion protein and use thereof
|
TW202304994A
(zh)
|
2021-04-02 |
2023-02-01 |
美商泰尼歐生物公司 |
促效性抗il-2r抗體及使用方法
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
BR112023020832A2
(pt)
|
2021-04-08 |
2023-12-19 |
Marengo Therapeutics Inc |
Moléculas multifuncionais ligadas a tcr e seus usos
|
US20240182572A1
(en)
|
2021-04-09 |
2024-06-06 |
Ose Immunotherapeutics |
Scaffold for bifunctional molecules comprising pd-1 or cd28 and sirp binding domains
|
JP2024513474A
(ja)
|
2021-04-09 |
2024-03-25 |
エフ. ホフマン-ラ ロシュ アーゲー |
異種ポリペプチドを発現する細胞クローンを選択するための方法
|
CA3213917A1
(en)
|
2021-04-09 |
2022-10-13 |
Nicolas Poirier |
New scaffold for bifunctional molecules with improved properties
|
TW202304524A
(zh)
|
2021-04-10 |
2023-02-01 |
美商普方生物製藥美國公司 |
Folr1結合劑、其結合物及使用方法
|
CA3214934A1
(en)
|
2021-04-12 |
2022-10-20 |
Madhavan Nallani |
Polymersomes comprising a soluble encapsulated polynucleotide and an ionizable lipid as well as methods of making and uses thereof
|
US20240190993A1
(en)
|
2021-04-14 |
2024-06-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to improve the anti-tumoral activity of macrophages
|
US20240228659A1
(en)
|
2021-04-14 |
2024-07-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to improve nk cells cytotoxicity
|
AR125344A1
(es)
|
2021-04-15 |
2023-07-05 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-c1s
|
KR20230173164A
(ko)
|
2021-04-19 |
2023-12-26 |
제넨테크, 인크. |
변형된 포유류 세포
|
EP4328243A1
(en)
|
2021-04-20 |
2024-02-28 |
Korea University Research and Business Foundation |
Asymmetric antibody with improved cytotoxicity against cancer cell
|
CN115925967A
(zh)
|
2021-04-22 |
2023-04-07 |
广东菲鹏制药股份有限公司 |
双特异性多功能融合多肽
|
TW202308699A
(zh)
|
2021-04-23 |
2023-03-01 |
美商普方生物製藥美國公司 |
Cd70結合劑、其結合物及其使用方法
|
JP2024515793A
(ja)
|
2021-04-27 |
2024-04-10 |
ノバルティス アーゲー |
ウイルスベクター生産システム
|
CN117321078A
(zh)
|
2021-04-30 |
2023-12-29 |
豪夫迈·罗氏有限公司 |
针对用抗cd20/抗cd3双特异性抗体和抗cd79b抗体药物缀合物进行组合治疗的给药
|
EP4329800A1
(en)
|
2021-04-30 |
2024-03-06 |
F. Hoffmann-La Roche AG |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibody
|
BR112023022844A2
(pt)
|
2021-05-03 |
2024-01-23 |
UCB Biopharma SRL |
Anticorpos
|
BR112023022878A2
(pt)
|
2021-05-04 |
2024-01-23 |
Regeneron Pharma |
Agonistas do receptor fgf21 multiespecíficos e seus usos
|
CN117597365A
(zh)
|
2021-05-04 |
2024-02-23 |
再生元制药公司 |
多特异性fgf21受体激动剂及其应用
|
US20220372165A1
(en)
|
2021-05-05 |
2022-11-24 |
Immatics Biotechnologies Gmbh |
Antigen binding proteins specifically binding prame
|
WO2022233957A1
(en)
|
2021-05-05 |
2022-11-10 |
Immatics Biotechnologies Gmbh |
Bma031 antigen binding polypeptides
|
EP4334343A2
(en)
|
2021-05-06 |
2024-03-13 |
The Rockefeller University |
Neutralizing anti-sars- cov-2 antibodies and methods of use thereof
|
KR20240005809A
(ko)
|
2021-05-07 |
2024-01-12 |
서피스 온콜로지, 엘엘씨 |
항-il-27 항체 및 이의 용도
|
US20240279310A1
(en)
|
2021-05-07 |
2024-08-22 |
Alpine Immune Sciences, Inc. |
Methods of dosing and treatment with a taci-fc fusion immunomodulatory protein
|
WO2022234146A1
(en)
|
2021-05-07 |
2022-11-10 |
Genmab A/S |
PHARMACEUTICAL COMPOSITIONS COMPRISING BISPECIFIC ANTIBODIES BINDING TO B7H4 and CD3
|
WO2022238481A1
(en)
|
2021-05-11 |
2022-11-17 |
Modiquest B.V. |
Antibodies
|
MX2023013264A
(es)
|
2021-05-12 |
2023-11-30 |
Genentech Inc |
Metodos para usar inmunoconjugados anti-cd79b para tratar linfoma difuso de linfocitos b grandes.
|
US20240254245A1
(en)
|
2021-05-12 |
2024-08-01 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Antigen binding molecule specifically binding to rankl and ngf, and medical use thereof
|
CN117396510A
(zh)
|
2021-05-14 |
2024-01-12 |
基因泰克公司 |
Trem2的激动剂
|
CA3219388A1
(en)
|
2021-05-14 |
2022-11-17 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Antigen-binding molecule
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
WO2022243261A1
(en)
|
2021-05-19 |
2022-11-24 |
F. Hoffmann-La Roche Ag |
Agonistic cd40 antigen binding molecules targeting cea
|
JP2024521107A
(ja)
|
2021-05-21 |
2024-05-28 |
ジェネンテック, インコーポレイテッド |
目的の組換え産物を産生するための修飾細胞
|
CN113278071B
(zh)
|
2021-05-27 |
2021-12-21 |
江苏荃信生物医药股份有限公司 |
抗人干扰素α受体1单克隆抗体及其应用
|
AR126009A1
(es)
|
2021-06-02 |
2023-08-30 |
Hoffmann La Roche |
Moléculas agonistas de unión al antígeno cd28 que se dirigen a epcam
|
TW202306994A
(zh)
|
2021-06-04 |
2023-02-16 |
日商中外製藥股份有限公司 |
抗ddr2抗體及其用途
|
AU2022289684A1
(en)
|
2021-06-09 |
2023-10-05 |
F. Hoffmann-La Roche Ag |
Combination of a particular braf inhibitor (paradox breaker) and a pd-1 axis binding antagonist for use in the treatment of cancer
|
CA3218481A1
(en)
|
2021-06-14 |
2022-12-22 |
argenx BV |
Anti-il-9 antibodies and methods of use thereof
|
WO2022262959A1
(en)
|
2021-06-15 |
2022-12-22 |
Astellas Pharma Europe Bv |
Bispecific binding agents binding to cldn18.2 and cd3
|
JP2024523166A
(ja)
|
2021-06-15 |
2024-06-28 |
ゼンコア インコーポレイテッド |
クローディン18.2及びcd3に結合するヘテロ二量体抗体
|
EP4355783A1
(en)
|
2021-06-16 |
2024-04-24 |
Alector LLC |
Monovalent anti-mertk antibodies and methods of use thereof
|
CN117642426A
(zh)
|
2021-06-16 |
2024-03-01 |
艾莱克特有限责任公司 |
双特异性抗MerTK和抗PDL1抗体及其使用方法
|
WO2022263638A1
(en)
|
2021-06-17 |
2022-12-22 |
Centre Hospitalier Universitaire Vaudois (C.H.U.V.) |
Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
|
KR20240021859A
(ko)
|
2021-06-18 |
2024-02-19 |
에프. 호프만-라 로슈 아게 |
이중특이적 항-ccl2 항체
|
JP2023535884A
(ja)
|
2021-06-22 |
2023-08-22 |
ノバルティス アーゲー |
化膿性汗腺炎の処置における使用のための二特異性抗体
|
AU2022299282A1
(en)
|
2021-06-22 |
2024-02-01 |
Merck Patent Gmbh |
Vhh-based nkp30 binders
|
CN117616123A
(zh)
|
2021-06-25 |
2024-02-27 |
中外制药株式会社 |
抗ctla-4抗体
|
BR112023023480A2
(pt)
|
2021-06-25 |
2024-01-30 |
Chugai Pharmaceutical Co Ltd |
Uso de anticorpo anti-ctla-4
|
CN117580865A
(zh)
|
2021-06-29 |
2024-02-20 |
山东先声生物制药有限公司 |
Cd16抗体及其应用
|
KR20240028452A
(ko)
|
2021-07-02 |
2024-03-05 |
제넨테크, 인크. |
암을 치료하기 위한 방법 및 조성물
|
TW202320857A
(zh)
|
2021-07-06 |
2023-06-01 |
美商普方生物製藥美國公司 |
連接子、藥物連接子及其結合物及其使用方法
|
WO2023283345A1
(en)
|
2021-07-07 |
2023-01-12 |
Incyte Corporation |
Anti-b7-h4 antibodies and uses thereof
|
EP4371125A1
(en)
|
2021-07-13 |
2024-05-22 |
Genentech, Inc. |
Multi-variate model for predicting cytokine release syndrome
|
WO2023284829A1
(zh)
|
2021-07-14 |
2023-01-19 |
江苏恒瑞医药股份有限公司 |
特异性结合hgfr和egfr的抗原结合分子及其医药用途
|
EP4370139A2
(en)
|
2021-07-14 |
2024-05-22 |
Synthekine, Inc. |
Methods and compositions for use in cell therapy of neoplastic disease
|
EP4370553A1
(en)
|
2021-07-14 |
2024-05-22 |
Genentech, Inc. |
Anti-c-c motif chemokine receptor 8 (ccr8) antibodies and methods of use
|
JP2024528665A
(ja)
|
2021-07-19 |
2024-07-30 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
Il12受容体アゴニスト及びその使用方法
|
AU2022315528A1
(en)
|
2021-07-22 |
2023-10-19 |
F. Hoffmann-La Roche Ag |
Heterodimeric fc domain antibodies
|
EP4373576A1
(en)
|
2021-07-22 |
2024-05-29 |
Genentech, Inc. |
Brain targeting compositions and methods of use thereof
|
WO2023010021A1
(en)
|
2021-07-27 |
2023-02-02 |
Xencor, Inc. |
Il-18-fc fusion proteins
|
CN117715939A
(zh)
|
2021-07-27 |
2024-03-15 |
莫佛塞斯公司 |
抗原结合分子的组合
|
KR20240042442A
(ko)
|
2021-07-28 |
2024-04-02 |
제넨테크, 인크. |
혈액암 치료를 위한 IL15/IL15R 알파 이종이량체 Fc-융합 단백질
|
EP4377351A1
(en)
|
2021-07-28 |
2024-06-05 |
F. Hoffmann-La Roche AG |
Methods and compositions for treating cancer
|
IL308154A
(en)
|
2021-07-30 |
2023-12-01 |
Affimed Gmbh |
Double structure antibodies
|
CA3231174A1
(en)
|
2021-08-02 |
2023-02-09 |
Innovent Biologics (Suzhou) Co., Ltd. |
Anti-cd79bxcd3 bispecific antibody and use thereof
|
EP4380980A1
(en)
|
2021-08-03 |
2024-06-12 |
F. Hoffmann-La Roche AG |
Bispecific antibodies and methods of use
|
AU2022324456A1
(en)
|
2021-08-05 |
2024-02-15 |
Go Therapeutics, Inc. |
Anti-glyco-muc4 antibodies and their uses
|
CN115702931A
(zh)
|
2021-08-06 |
2023-02-17 |
百奥泰生物制药股份有限公司 |
抗pd-l1/cd47双特异抗体在治疗疾病中的应用
|
EP4384553A1
(en)
|
2021-08-13 |
2024-06-19 |
Genentech, Inc. |
Dosing for anti-tryptase antibodies
|
KR20240046251A
(ko)
|
2021-08-16 |
2024-04-08 |
리제너론 파아마슈티컬스, 인크. |
신규 il27 수용체 효능제 및 그의 사용 방법
|
GB202111905D0
(en)
|
2021-08-19 |
2021-10-06 |
UCB Biopharma SRL |
Antibodies
|
JP2024531364A
(ja)
|
2021-08-20 |
2024-08-29 |
ノバルティス アーゲー |
キメラ抗原受容体発現細胞を作製する方法
|
CN118284623A
(zh)
|
2021-08-23 |
2024-07-02 |
伊莫尼塔斯治疗公司 |
抗cd161抗体及其用途
|
WO2023028612A2
(en)
|
2021-08-27 |
2023-03-02 |
Board Of Regents, The University Of Texas System |
Anti-tslpr (crlf2) antibodies
|
KR20240049296A
(ko)
|
2021-08-27 |
2024-04-16 |
제넨테크, 인크. |
타우 병증을 치료하는 방법
|
TW202325727A
(zh)
|
2021-08-30 |
2023-07-01 |
美商建南德克公司 |
抗聚泛素多特異性抗體
|
KR20240101546A
(ko)
|
2021-09-03 |
2024-07-02 |
고 테라퓨틱스, 인크. |
항-글리코-lamp1 항체 및 그의 용도
|
CN113603775B
(zh)
|
2021-09-03 |
2022-05-20 |
江苏荃信生物医药股份有限公司 |
抗人白介素-33单克隆抗体及其应用
|
WO2023031435A1
(en)
|
2021-09-03 |
2023-03-09 |
Cancer Research Technology Limited |
Treatment and prevention of cancer using her3 antigen-binding molecules
|
CN113683694B
(zh)
|
2021-09-03 |
2022-05-13 |
江苏荃信生物医药股份有限公司 |
一种抗人tslp单克隆抗体及其应用
|
CN118354789A
(zh)
|
2021-09-03 |
2024-07-16 |
Go医疗股份有限公司 |
抗糖-cMET抗体及其用途
|
EP4148067A1
(en)
|
2021-09-08 |
2023-03-15 |
F. Hoffmann-La Roche AG |
Method for the expression of an antibody-multimer-fusion
|
WO2023038548A1
(ru)
|
2021-09-08 |
2023-03-16 |
Акционерное общество "БИОКАД" |
Биспецифическое антитело, содержащее гетеродимер на основе мнс белков
|
EP4402171A1
(en)
|
2021-09-13 |
2024-07-24 |
Janssen Biotech, Inc. |
Cd33 x v delta 2 multispecific antibodies for the treatment of cancer
|
TW202328196A
(zh)
|
2021-09-16 |
2023-07-16 |
新加坡商蜂鳥生物科技私人有限公司 |
使用vista抗原結合分子的癌症之治療及預防
|
WO2023044483A2
(en)
|
2021-09-20 |
2023-03-23 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
EP4406968A1
(en)
|
2021-09-23 |
2024-07-31 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Anti-klb antibodies and uses
|
WO2023046322A1
(en)
|
2021-09-24 |
2023-03-30 |
Janssen Pharmaceutica Nv |
Proteins comprising cd20 binding domains, and uses thereof
|
CN118043356A
(zh)
|
2021-09-27 |
2024-05-14 |
Xencor股份有限公司 |
B细胞成熟抗原(bcma)结合结构域组合物
|
WO2023046979A1
(en)
|
2021-09-27 |
2023-03-30 |
Hummingbird Bioscience Pte. Ltd. |
Treatment and prevention of cancer using vista antigen-binding molecules
|
JPWO2023053282A1
(fi)
|
2021-09-29 |
2023-04-06 |
|
|
EP4410841A1
(en)
|
2021-09-30 |
2024-08-07 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Anti-il23 antibody fusion protein and uses thereof
|
CN118414353A
(zh)
|
2021-10-08 |
2024-07-30 |
根马布股份公司 |
与cd30和cd3结合的抗体
|
EP4413027A2
(en)
|
2021-10-08 |
2024-08-14 |
CytomX Therapeutics, Inc. |
Activatable cytokine constructs and related compositions and methods
|
WO2023058705A1
(ja)
|
2021-10-08 |
2023-04-13 |
中外製薬株式会社 |
抗hla-dq2.5抗体の製剤
|
WO2023060188A1
(en)
|
2021-10-08 |
2023-04-13 |
Cytomx Therapeutics, Inc. |
Activatable cytokine constructs and combination methods
|
CA3234966A1
(en)
|
2021-10-14 |
2023-04-20 |
Teneobio, Inc. |
Mesothelin binding proteins and uses thereof
|
CA3234731A1
(en)
|
2021-10-14 |
2023-04-20 |
F. Hoffmann-La Roche Ag |
New interleukin-7 immunoconjugates
|
CN118139648A
(zh)
|
2021-10-14 |
2024-06-04 |
豪夫迈·罗氏有限公司 |
用于治疗癌症的替代的PD1-IL7v免疫缀合物
|
EP4415822A1
(en)
|
2021-10-15 |
2024-08-21 |
RegenxBio Inc. |
Antibodies and methods of using thereof
|
WO2023076876A1
(en)
|
2021-10-26 |
2023-05-04 |
Mozart Therapeutics, Inc. |
Modulation of immune responses to viral vectors
|
WO2023072159A1
(en)
|
2021-10-27 |
2023-05-04 |
Virtuoso Binco, Inc. |
Multispecific antibodies for treating cd47-associated diseases
|
CN118119642A
(zh)
|
2021-10-28 |
2024-05-31 |
诺华股份有限公司 |
工程化Fc变体
|
WO2023073615A1
(en)
|
2021-10-29 |
2023-05-04 |
Janssen Biotech, Inc. |
Methods of treating crohn's disease with anti-il23 specific antibody
|
TW202325742A
(zh)
|
2021-11-01 |
2023-07-01 |
瑞士商赫孚孟拉羅股份公司 |
使用 HLA-A2/WT1 x CD3 雙特異性抗體及 4-1BB (CD137) 促效劑治療癌症
|
WO2023081898A1
(en)
|
2021-11-08 |
2023-05-11 |
Alector Llc |
Soluble cd33 as a biomarker for anti-cd33 efficacy
|
EP4430072A1
(en)
|
2021-11-10 |
2024-09-18 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
US20230279153A1
(en)
|
2021-11-11 |
2023-09-07 |
Regeneron Pharmaceuticals, Inc. |
Cd20-pd1 binding molecules and methods of use thereof
|
US20230151095A1
(en)
|
2021-11-12 |
2023-05-18 |
Xencor, Inc. |
Bispecific antibodies that bind to b7h3 and nkg2d
|
CA3238377A1
(en)
|
2021-11-15 |
2023-05-19 |
Janssen Biotech, Inc. |
Methods of treating crohn's disease with anti-il23 specific antibody
|
WO2023088889A1
(en)
|
2021-11-16 |
2023-05-25 |
Apogenix Ag |
CD137 ligands
|
WO2023088876A1
(en)
|
2021-11-16 |
2023-05-25 |
Apogenix Ag |
Multi-specific immune modulators
|
WO2023092004A1
(en)
|
2021-11-17 |
2023-05-25 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
KR20240111783A
(ko)
|
2021-11-22 |
2024-07-17 |
얀센 바이오테크 인코포레이티드 |
면역 반응을 위한 강화된 다중특이성 결합제를 포함하는 조성물
|
WO2023095000A1
(en)
|
2021-11-23 |
2023-06-01 |
Janssen Biotech, Inc. |
Method of treating ulcerative colitis with anti-il23 specific antibody
|
WO2023092324A1
(zh)
|
2021-11-24 |
2023-06-01 |
苏州光度生物科技有限公司 |
多特异性配体结合分子及其应用
|
WO2023094282A1
(en)
|
2021-11-25 |
2023-06-01 |
F. Hoffmann-La Roche Ag |
Quantification of low amounts of antibody sideproducts
|
WO2023094569A1
(en)
|
2021-11-26 |
2023-06-01 |
F. Hoffmann-La Roche Ag |
Combination therapy of anti-tyrp1/anti-cd3 bispecific antibodies and tyrp1-specific antibodies
|
IL312728A
(en)
|
2021-11-30 |
2024-07-01 |
Daiichi Sankyo Co Ltd |
Antibodies masked in protease-wells
|
CA3239389A1
(en)
|
2021-12-01 |
2023-06-08 |
Kohei SOEDA |
Method for preparing antibody-containing formulation
|
EP4428156A1
(en)
|
2021-12-03 |
2024-09-11 |
Shandong Simcere Biopharmaceutical Co., Ltd. |
Anti-bcma nanobody and use thereof
|
WO2023103788A1
(zh)
|
2021-12-06 |
2023-06-15 |
北京三诺佳邑生物技术有限责任公司 |
特异性结合肺炎克雷伯菌o2抗原和o1抗原的双特异性抗体以及组合物
|
CA3241889A1
(en)
|
2021-12-08 |
2023-06-15 |
Incyte Corporation |
Anti-mutant calreticulin (calr) antibodies and uses thereof
|
AR127887A1
(es)
|
2021-12-10 |
2024-03-06 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y plap
|
KR20240116829A
(ko)
|
2021-12-13 |
2024-07-30 |
윌리엄 로버트 아라툰 리빙 트러스트 데이티드 어거스트 29, 2016 |
항-abcb1 항체
|
CN118541382A
(zh)
|
2021-12-14 |
2024-08-23 |
豪夫迈·罗氏有限公司 |
使用HLA-A2/MAGE-A4 x CD3双特异性抗体和4-1BB(CD137)激动剂治疗癌症
|
CN118574849A
(zh)
|
2021-12-17 |
2024-08-30 |
上海复宏汉霖生物技术股份有限公司 |
抗ox40抗体和使用方法
|
WO2023109900A1
(en)
|
2021-12-17 |
2023-06-22 |
Shanghai Henlius Biotech, Inc. |
Anti-ox40 antibodies, multispecific antibodies and methods of use
|
AU2022423749A1
(en)
|
2021-12-20 |
2024-06-13 |
F. Hoffmann-La Roche Ag |
Agonistic ltbr antibodies and bispecific antibodies comprising them
|
CN118401674A
(zh)
|
2021-12-21 |
2024-07-26 |
豪夫迈·罗氏有限公司 |
用于确定水解活性的方法
|
US20230357392A1
(en)
|
2021-12-22 |
2023-11-09 |
Morphosys Ag |
Treatment Paradigm for an Anti-CD19 Antibody Therapy
|
WO2023116861A1
(zh)
|
2021-12-23 |
2023-06-29 |
江苏恒瑞医药股份有限公司 |
抗dll3抗体、其抗体-药物偶联物及其医药用途
|
KR20240128067A
(ko)
|
2021-12-29 |
2024-08-23 |
브리스톨-마이어스 스큅 컴퍼니 |
랜딩 패드 세포주의 생성
|
WO2023125888A1
(zh)
|
2021-12-31 |
2023-07-06 |
山东先声生物制药有限公司 |
一种gprc5d抗体及其应用
|
WO2023141445A1
(en)
|
2022-01-19 |
2023-07-27 |
Genentech, Inc. |
Anti-notch2 antibodies and conjugates and methods of use
|
AR128330A1
(es)
|
2022-01-26 |
2024-04-17 |
Genentech Inc |
Inductores químicos de degradación conjugados con anticuerpo y métodos de estos
|
WO2023147331A1
(en)
|
2022-01-26 |
2023-08-03 |
Mabswitch Inc. |
Bispecific molecule with tunable affinity to a targetted antigen
|
AR128331A1
(es)
|
2022-01-26 |
2024-04-17 |
Genentech Inc |
Inductores químicos de degradación conjugados con anticuerpos y métodos de estos
|
WO2023147399A1
(en)
|
2022-01-27 |
2023-08-03 |
The Rockefeller University |
Broadly neutralizing anti-sars-cov-2 antibodies targeting the n-terminal domain of the spike protein and methods of use thereof
|
CN118574855A
(zh)
|
2022-02-07 |
2024-08-30 |
江苏恒瑞医药股份有限公司 |
特异性结合psma和cd3的抗原结合分子及其医药用途
|
WO2023150778A1
(en)
|
2022-02-07 |
2023-08-10 |
Visterra, Inc. |
Anti-idiotype antibody molecules and uses thereof
|
CN118591564A
(zh)
|
2022-02-10 |
2024-09-03 |
上海齐鲁制药研究中心有限公司 |
一种双特异性抗原结合分子及其应用
|
WO2023151661A1
(zh)
|
2022-02-11 |
2023-08-17 |
江苏恒瑞医药股份有限公司 |
免疫缀合物及其用途
|
WO2023154953A1
(en)
|
2022-02-14 |
2023-08-17 |
Ngm Biopharmaceuticals, Inc. |
Gdf15 polypeptides for treating and preventing autoimmune diseases
|
WO2023159220A1
(en)
|
2022-02-18 |
2023-08-24 |
Kenjockety Biotechnology, Inc. |
Anti-cd47 antibodies
|
TW202337895A
(zh)
|
2022-02-21 |
2023-10-01 |
比利時商阿根思公司 |
使用fcrn拮抗劑治療肌炎之方法
|
US20230265218A1
(en)
|
2022-02-23 |
2023-08-24 |
Xencor, Inc. |
Anti-cd28 x anti-psma antibodies
|
US20240059786A1
(en)
|
2022-02-24 |
2024-02-22 |
Xencor, Inc. |
Anti-cd28 x anti-trop2 antibodies
|
WO2023164627A1
(en)
|
2022-02-24 |
2023-08-31 |
Xencor, Inc. |
Anti-cd28 x anti-msln antibodies
|
WO2023161457A1
(en)
|
2022-02-27 |
2023-08-31 |
Evobright Gmbh |
Bispecific antibodies against cd277 and a tumor-antigen
|
WO2023164286A1
(en)
|
2022-02-28 |
2023-08-31 |
Xilio Development, Inc. |
Engineered cd122 compositions and methods thereof
|
AU2023225803A1
(en)
|
2022-02-28 |
2024-08-08 |
Xilio Development, Inc. |
Targeted cytokines and methods of use thereof
|
WO2023166420A1
(en)
|
2022-03-03 |
2023-09-07 |
Pfizer Inc. |
Multispecific antibodies and uses thereof
|
WO2023172883A1
(en)
|
2022-03-07 |
2023-09-14 |
Alpine Immune Sciences, Inc. |
Immunomodulatory proteins of variant cd80 polypeptides, cell therapies thereof and related methods and uses
|
WO2023173026A1
(en)
|
2022-03-10 |
2023-09-14 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
TW202346355A
(zh)
|
2022-03-11 |
2023-12-01 |
比利時商健生藥品公司 |
多特異性抗體及其用途(二)
|
TW202400636A
(zh)
|
2022-03-11 |
2024-01-01 |
比利時商健生藥品公司 |
多特異性抗體及其用途(一)
|
TW202346594A
(zh)
*
|
2022-03-11 |
2023-12-01 |
中國大陸商科望(上海)生物醫藥科技有限公司 |
經修飾之抗體及其用途
|
WO2023170295A1
(en)
|
2022-03-11 |
2023-09-14 |
Janssen Pharmaceutica Nv |
Multispecific antibodies and uses thereof
|
WO2023174521A1
(en)
|
2022-03-15 |
2023-09-21 |
Genmab A/S |
Binding agents binding to epcam and cd137
|
WO2023178357A1
(en)
|
2022-03-18 |
2023-09-21 |
Evolveimmune Therapeutics, Inc. |
Bispecific antibody fusion molecules and methods of use thereof
|
TW202346365A
(zh)
|
2022-03-23 |
2023-12-01 |
瑞士商赫孚孟拉羅股份公司 |
抗cd20/抗cd3雙特異性抗體及化學療法之組合治療
|
WO2023179740A1
(en)
|
2022-03-25 |
2023-09-28 |
Shanghai Henlius Biotech , Inc. |
Anti-msln antibodies and methods of use
|
WO2023186756A1
(en)
|
2022-03-28 |
2023-10-05 |
F. Hoffmann-La Roche Ag |
Interferon gamma variants and antigen binding molecules comprising these
|
AR128876A1
(es)
|
2022-03-28 |
2024-06-19 |
Hoffmann La Roche |
Anticuerpos biespecíficos de linfocitos t activables con proteasa folr1 mejorados
|
US20230312703A1
(en)
|
2022-03-30 |
2023-10-05 |
Janssen Biotech, Inc. |
Method of Treating Psoriasis with IL-23 Specific Antibody
|
GB202204813D0
(en)
|
2022-04-01 |
2022-05-18 |
Bradcode Ltd |
Human monoclonal antibodies and methods of use thereof
|
US20230364020A1
(en)
|
2022-04-01 |
2023-11-16 |
Genentech, Inc. |
Hydroxypropyl methyl cellulose derivatives to stabilize polypeptides
|
WO2023191816A1
(en)
|
2022-04-01 |
2023-10-05 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2023192973A1
(en)
|
2022-04-01 |
2023-10-05 |
Cytomx Therapeutics, Inc. |
Activatable multispecific molecules and methods of use thereof
|
WO2023192606A2
(en)
|
2022-04-01 |
2023-10-05 |
Cytomx Therapeutics, Inc. |
Cd3-binding proteins and methods of use thereof
|
WO2023196905A1
(en)
|
2022-04-07 |
2023-10-12 |
Xencor, Inc. |
Lag-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and lag-3 antigen binding domains
|
WO2023193239A1
(en)
|
2022-04-08 |
2023-10-12 |
Peter Peizhi Luo |
Anti-cd28 antibodies and methods of use thereof
|
WO2023201309A1
(en)
|
2022-04-13 |
2023-10-19 |
Xencor, Inc. |
Antibodies that bind pd-l1, pd-l2 and/or cd28
|
US20230406930A1
(en)
|
2022-04-13 |
2023-12-21 |
Genentech, Inc. |
Pharmaceutical compositions of therapeutic proteins and methods of use
|
TW202404637A
(zh)
|
2022-04-13 |
2024-02-01 |
瑞士商赫孚孟拉羅股份公司 |
抗cd20/抗cd3雙特異性抗體之醫藥組成物及使用方法
|
WO2023202967A1
(en)
|
2022-04-19 |
2023-10-26 |
F. Hoffmann-La Roche Ag |
Improved production cells
|
WO2023209568A1
(en)
|
2022-04-26 |
2023-11-02 |
Novartis Ag |
Multispecific antibodies targeting il-13 and il-18
|
WO2023209124A1
(en)
|
2022-04-29 |
2023-11-02 |
Immatics Biotechnologies Gmbh |
Mammalian display platform for multispecific antigen binding proteins
|
US11780910B1
(en)
|
2022-05-02 |
2023-10-10 |
Novo Nordisk A/S |
Anti-ANGPTL3 antibodies suitable for high concentration compositions and subcutaneous administration
|
WO2023215737A1
(en)
|
2022-05-03 |
2023-11-09 |
Genentech, Inc. |
Anti-ly6e antibodies, immunoconjugates, and uses thereof
|
WO2023215498A2
(en)
|
2022-05-05 |
2023-11-09 |
Modernatx, Inc. |
Compositions and methods for cd28 antagonism
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
WO2023220647A1
(en)
|
2022-05-11 |
2023-11-16 |
Regeneron Pharmaceuticals, Inc. |
Multispecific binding molecule proproteins and uses thereof
|
US20240059799A1
(en)
|
2022-05-11 |
2024-02-22 |
Pfizer Inc. |
Anti-tl1a antibodies and methods of use thereof
|
WO2023219613A1
(en)
|
2022-05-11 |
2023-11-16 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2023220695A2
(en)
|
2022-05-13 |
2023-11-16 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
WO2023218431A1
(en)
|
2022-05-13 |
2023-11-16 |
BioNTech SE |
Rna compositions targeting hiv
|
WO2023223265A1
(en)
|
2022-05-18 |
2023-11-23 |
Janssen Biotech, Inc. |
Method for evaluating and treating psoriatic arthritis with il23 antibody
|
WO2023230594A1
(en)
|
2022-05-27 |
2023-11-30 |
Regeneron Pharmaceuticals, Inc. |
Interleukin-2 proproteins and uses thereof
|
US20230416412A1
(en)
|
2022-05-31 |
2023-12-28 |
Hoffmann-La Roche Inc. |
Prevention or mitigation of t-cell engaging agent-related adverse effects
|
WO2023232961A1
(en)
|
2022-06-03 |
2023-12-07 |
F. Hoffmann-La Roche Ag |
Improved production cells
|
WO2023235848A1
(en)
|
2022-06-04 |
2023-12-07 |
Regeneron Pharmaceuticals, Inc. |
Interleukin-2 proproteins and uses thereof
|
WO2023237690A2
(en)
|
2022-06-08 |
2023-12-14 |
Sanofi |
Methods for purification of multi-specific antibodies
|
WO2023242372A1
(en)
|
2022-06-15 |
2023-12-21 |
argenx BV |
Fcrn/hsa binding molecules and methods of use
|
AU2023295035A1
(en)
|
2022-06-17 |
2024-08-15 |
Genentech, Inc. |
Use of kosmotropes to enhance yield of an affinity chromatography purification step
|
WO2024015897A1
(en)
|
2022-07-13 |
2024-01-18 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
TW202417474A
(zh)
|
2022-07-15 |
2024-05-01 |
美商艾希利歐發展股份有限公司 |
經改造之可裂解載體及其使用方法
|
US20240052065A1
(en)
|
2022-07-15 |
2024-02-15 |
Boehringer Ingelheim International Gmbh |
Binding molecules for the treatment of cancer
|
WO2024013727A1
(en)
|
2022-07-15 |
2024-01-18 |
Janssen Biotech, Inc. |
Material and methods for improved bioengineered pairing of antigen-binding variable regions
|
WO2024020051A1
(en)
|
2022-07-19 |
2024-01-25 |
BioLegend, Inc. |
Anti-cd157 antibodies, antigen-binding fragments thereof and compositions and methods for making and using the same
|
TW202413433A
(zh)
|
2022-07-19 |
2024-04-01 |
美商建南德克公司 |
用抗fcrh5/抗cd3雙特異性抗體進行治療之給藥
|
TW202417504A
(zh)
|
2022-07-22 |
2024-05-01 |
美商建南德克公司 |
抗steap1抗原結合分子及其用途
|
US20240228664A9
(en)
|
2022-07-22 |
2024-07-11 |
Bristol-Myers Squibb Company |
Antibodies Binding to Human PAD4 and Uses Thereof
|
US20240132624A1
(en)
|
2022-07-27 |
2024-04-25 |
Ablynx N.V. |
Polypeptides binding to a specific epitope of the neonatal fc receptor
|
WO2024026358A1
(en)
|
2022-07-27 |
2024-02-01 |
Teneobio, Inc. |
Mesothelin binding proteins and uses thereof
|
TW202412859A
(zh)
|
2022-07-28 |
2024-04-01 |
英商阿斯特捷利康英國股份有限公司 |
抗體-藥物結合物及雙特異性檢查點抑制劑之組合
|
WO2024026472A2
(en)
|
2022-07-29 |
2024-02-01 |
Alector Llc |
Transferrin receptor antigen-binding domains and uses therefor
|
WO2024026471A1
(en)
|
2022-07-29 |
2024-02-01 |
Alector Llc |
Cd98hc antigen-binding domains and uses therefor
|
TW202423953A
(zh)
|
2022-08-01 |
2024-06-16 |
美商Cytomx生物製藥公司 |
蛋白酶可切割部分及其使用方法
|
TW202424183A
(zh)
|
2022-08-01 |
2024-06-16 |
美商Cytomx生物製藥公司 |
蛋白酶可切割受質及其使用方法
|
TW202424184A
(zh)
|
2022-08-01 |
2024-06-16 |
美商Cytomx生物製藥公司 |
蛋白酶可切割部分及其使用方法
|
WO2024030843A1
(en)
|
2022-08-01 |
2024-02-08 |
Cytomx Therapeutics, Inc. |
Protease-cleavable moieties and methods of use thereof
|
WO2024030858A1
(en)
|
2022-08-01 |
2024-02-08 |
Cytomx Therapeutics, Inc. |
Protease-cleavable substrates and methods of use thereof
|
WO2024028386A1
(en)
|
2022-08-02 |
2024-02-08 |
Ose Immunotherapeutics |
Multifunctional molecule directed against cd28
|
WO2024030976A2
(en)
|
2022-08-03 |
2024-02-08 |
Voyager Therapeutics, Inc. |
Compositions and methods for crossing the blood brain barrier
|
US20240052047A1
(en)
|
2022-08-03 |
2024-02-15 |
Pfizer Inc. |
Anti- il27r antibodies and methods of use thereof
|
WO2024030956A2
(en)
|
2022-08-03 |
2024-02-08 |
Mozart Therapeutics, Inc. |
Cd39-specific binding agents and methods of using the same
|
WO2024036139A2
(en)
|
2022-08-09 |
2024-02-15 |
Qlsf Biotherapeutics, Inc. |
Antibodies binding to clec12a
|
WO2024040114A2
(en)
|
2022-08-18 |
2024-02-22 |
BioLegend, Inc. |
Anti-axl antibodies, antigen-binding fragments thereof and methods for making and using the same
|
WO2024040247A1
(en)
|
2022-08-18 |
2024-02-22 |
Regeneron Pharmaceuticals, Inc. |
Interferon proproteins and uses thereof
|
US20240067691A1
(en)
|
2022-08-18 |
2024-02-29 |
Regeneron Pharmaceuticals, Inc. |
Interferon receptor agonists and uses thereof
|
US20240092859A1
(en)
|
2022-08-18 |
2024-03-21 |
Immunocore Ltd |
T cell receptors and fusion proteins thereof
|
CN115353552B
(zh)
*
|
2022-08-19 |
2023-07-18 |
山东大学 |
一种降低蛋白质变性温度的方法及其突变体与应用
|
WO2024049949A1
(en)
|
2022-09-01 |
2024-03-07 |
Genentech, Inc. |
Therapeutic and diagnostic methods for bladder cancer
|
WO2024052922A1
(en)
|
2022-09-11 |
2024-03-14 |
Yeda Research And Development Co. Ltd. |
Anti-klk4 antibodies and uses thereof
|
TW202423983A
(zh)
|
2022-09-15 |
2024-06-16 |
瑞士商諾華公司 |
使用嵌合抗原受體療法的自體免疫性障礙的治療
|
WO2024059739A1
(en)
|
2022-09-15 |
2024-03-21 |
Voyager Therapeutics, Inc. |
Tau binding compounds
|
WO2024056862A1
(en)
|
2022-09-15 |
2024-03-21 |
Avidicure Ip B.V. |
Multispecific antigen binding proteins for tumor-targeting of nk cells and use thereof
|
WO2024062073A1
(en)
|
2022-09-22 |
2024-03-28 |
Hummingbird Bioscience Pte. Ltd. |
Treatment and prevention of cancer using vista antigen-binding molecules
|
US20240101718A1
(en)
|
2022-09-28 |
2024-03-28 |
Incyte Corporation |
Anti-pd-1/lag-3 bispecific antibodies and uses thereof
|
WO2024068572A1
(en)
|
2022-09-28 |
2024-04-04 |
F. Hoffmann-La Roche Ag |
Improved protease-activatable t cell bispecific antibodies
|
WO2024068996A1
(en)
|
2022-09-30 |
2024-04-04 |
Centre Hospitalier Universitaire Vaudois (C.H.U.V.) |
Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
|
WO2024077018A2
(en)
|
2022-10-04 |
2024-04-11 |
Alpine Immune Sciences, Inc. |
Methods and uses of taci-fc fusion immunomodulatory protein
|
WO2024077044A1
(en)
|
2022-10-05 |
2024-04-11 |
Amgen Inc. |
Combination therapies comprising t-cell redirecting therapies and agonistic anti-il-2r antibodies or fragments thereof
|
TW202421664A
(zh)
|
2022-10-07 |
2024-06-01 |
美商建南德克公司 |
用抗c—c模體趨化因子受體8(ccr8)抗體治療癌症之方法
|
TW202423969A
(zh)
|
2022-10-10 |
2024-06-16 |
瑞士商赫孚孟拉羅股份公司 |
Gprc5d tcb及蛋白酶體抑制劑之組合療法
|
TW202423970A
(zh)
|
2022-10-10 |
2024-06-16 |
瑞士商赫孚孟拉羅股份公司 |
Gprc5d tcb及cd38抗體之組合療法
|
WO2024079015A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and imids
|
WO2024079069A1
(en)
|
2022-10-12 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Method for classifying cells
|
WO2024086739A1
(en)
|
2022-10-20 |
2024-04-25 |
Synthekine, Inc. |
Methods and compositions of il12 muteins and il2 muteins
|
WO2024086796A1
(en)
|
2022-10-20 |
2024-04-25 |
Alector Llc |
Anti-ms4a4a antibodies with amyloid-beta therapies
|
US20240254234A1
(en)
|
2022-10-21 |
2024-08-01 |
Novimmune Sa |
PD-L1xCD28 BISPECIFIC ANTIBODIES FOR IMMUNE CHECKPOINT-DEPENDENT T CELL ACTIVATION
|
WO2024086852A1
(en)
|
2022-10-21 |
2024-04-25 |
Diagonal Therapeutics Inc. |
Heteromeric agonistic antibodies to il-18 receptor
|
WO2024088921A1
(en)
|
2022-10-24 |
2024-05-02 |
F. Hoffmann-La Roche Ag |
Predicting response to il-6 antagonists
|
WO2024091991A1
(en)
|
2022-10-25 |
2024-05-02 |
Genentech, Inc. |
Therapeutic and diagnostic methods for multiple myeloma
|
WO2024089639A1
(en)
|
2022-10-26 |
2024-05-02 |
Novartis Ag |
Lentiviral formulations
|
WO2024097639A1
(en)
|
2022-10-31 |
2024-05-10 |
Modernatx, Inc. |
Hsa-binding antibodies and binding proteins and uses thereof
|
WO2024095173A1
(en)
|
2022-11-02 |
2024-05-10 |
Janssen Biotech, Inc. |
Methods of treating cancers
|
WO2024097328A1
(en)
|
2022-11-03 |
2024-05-10 |
Incyte Corporation |
Combination therapies comprising an anti-gitr antibody for treating cancers
|
WO2024094741A1
(en)
|
2022-11-03 |
2024-05-10 |
F. Hoffmann-La Roche Ag |
Combination therapy with anti-cd19/anti-cd28 bispecific antibody
|
WO2024102636A1
(en)
|
2022-11-07 |
2024-05-16 |
Xencor, Inc. |
Bispecific antibodies that bind to b7h3 and mica/b
|
WO2024100455A1
(en)
|
2022-11-07 |
2024-05-16 |
argenx BV |
Methods for treating primary membranous nephropathy using fcrn antagonists
|
US20240166705A1
(en)
|
2022-11-07 |
2024-05-23 |
Xencor, Inc. |
Il18-fc fusion proteins
|
WO2024102734A1
(en)
|
2022-11-08 |
2024-05-16 |
Genentech, Inc. |
Compositions and methods of treating childhood onset idiopathic nephrotic syndrome
|
WO2024102962A1
(en)
|
2022-11-10 |
2024-05-16 |
Immuvia Inc |
Cytotoxic bispecific antibodies binding to dr5 and muc16 and uses thereof
|
WO2024100170A1
(en)
|
2022-11-11 |
2024-05-16 |
F. Hoffmann-La Roche Ag |
Antibodies binding to hla-a*02/foxp3
|
WO2024102948A1
(en)
|
2022-11-11 |
2024-05-16 |
Celgene Corporation |
Fc receptor-homolog 5 (fcrh5) specific binding molecules and bispecific t-cell engaging antibodies including same and related methods
|
WO2024104988A1
(en)
|
2022-11-15 |
2024-05-23 |
F. Hoffmann-La Roche Ag |
Recombinant binding proteins with activatable effector domain
|
WO2024104933A1
(en)
|
2022-11-15 |
2024-05-23 |
F. Hoffmann-La Roche Ag |
Antigen binding molecules
|
US20240226313A1
(en)
|
2022-11-17 |
2024-07-11 |
Sanofi |
Ceacam5 antibody-drug conjugates and methods of use thereof
|
WO2024110898A1
(en)
|
2022-11-22 |
2024-05-30 |
Janssen Biotech, Inc. |
Method of treating ulcerative colitis with anti-il23 specific antibody
|
WO2024110426A1
(en)
|
2022-11-23 |
2024-05-30 |
F. Hoffmann-La Roche Ag |
Method for increasing recombinant protein expression
|
WO2024110905A1
(en)
|
2022-11-24 |
2024-05-30 |
Beigene, Ltd. |
Anti-cea antibody drug conjugates and methods of use
|
WO2024115349A1
(en)
|
2022-11-29 |
2024-06-06 |
F. Hoffmann-La Roche Ag |
Improved cancer immunotherapy
|
WO2024118866A1
(en)
|
2022-12-01 |
2024-06-06 |
Modernatx, Inc. |
Gpc3-specific antibodies, binding domains, and related proteins and uses thereof
|
WO2024121798A1
(en)
|
2022-12-08 |
2024-06-13 |
Csl Behring Llc |
Dissociable envelope binding proteins and uses thereof
|
WO2024124107A2
(en)
|
2022-12-09 |
2024-06-13 |
Pfizer Inc. |
Cd47 blocking agent and anti-cd20 / anti-cd3 bispecific antibody combination therapy
|
WO2024129594A1
(en)
|
2022-12-12 |
2024-06-20 |
Genentech, Inc. |
Optimizing polypeptide sialic acid content
|
EP4385999A1
(en)
|
2022-12-14 |
2024-06-19 |
ModiQuest B.V. |
Antibodies
|
WO2024126457A1
(en)
|
2022-12-14 |
2024-06-20 |
Astellas Pharma Europe Bv |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and immune checkpoint inhibitors
|
WO2024126660A1
(en)
|
2022-12-15 |
2024-06-20 |
F. Hoffmann-La Roche Ag |
Combination therapy for cancer treatment
|
WO2024130175A2
(en)
|
2022-12-16 |
2024-06-20 |
Regeneron Pharmaceuticals, Inc. |
Antigen-binding molecules that bind to aav particles and uses
|
US20240209107A1
(en)
|
2022-12-19 |
2024-06-27 |
Sanofi |
Cd28/ox40 bispecific antibodies
|
WO2024133161A1
(en)
|
2022-12-19 |
2024-06-27 |
Astrazeneca Ab |
Treatment of autoimmune disease
|
US20240252601A1
(en)
|
2022-12-23 |
2024-08-01 |
Regeneron Pharmaceuticals, Inc. |
Ace2 fusion proteins and uses thereof
|
WO2024145398A1
(en)
|
2022-12-27 |
2024-07-04 |
Yale University |
Antibody drug conjugates
|
WO2024141955A1
(en)
|
2022-12-28 |
2024-07-04 |
BioNTech SE |
Rna compositions targeting hiv
|
WO2024147074A1
(en)
|
2023-01-06 |
2024-07-11 |
argenx BV |
Methods for treating pots using fcrn antagonists
|
WO2024146955A1
(en)
|
2023-01-06 |
2024-07-11 |
Twain Therapeutics Pte. Ltd. |
Antigen-binding molecules
|
WO2024146957A1
(en)
|
2023-01-06 |
2024-07-11 |
Twain Therapeutics Pte. Ltd. |
Antigen-binding molecules
|
WO2024150073A1
(en)
|
2023-01-12 |
2024-07-18 |
argenx BV |
Methods for treating primary sjogren's syndrome using fcrn antagonists
|
US20240270836A1
(en)
|
2023-01-13 |
2024-08-15 |
Regeneron Pharmaceuticals, Inc. |
Il12 receptor agonists and methods of use thereof
|
WO2024152014A1
(en)
|
2023-01-13 |
2024-07-18 |
Regeneron Pharmaceuticals, Inc. |
Fgfr3 binding molecules and methods of use thereof
|
WO2024149821A1
(en)
|
2023-01-13 |
2024-07-18 |
F. Hoffmann-La Roche Ag |
Treatment of cancer using a hla-a2/wt1 x cd3 bispecific antibody and venetoclax/azacitidine
|
WO2024155807A1
(en)
|
2023-01-18 |
2024-07-25 |
Genentech, Inc. |
Multispecific antibodies and uses thereof
|
WO2024153168A2
(en)
|
2023-01-19 |
2024-07-25 |
Beigene, Ltd. |
Anti-cmet antibodies and methods of use
|
WO2024153722A1
(en)
|
2023-01-20 |
2024-07-25 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
WO2024155982A2
(en)
|
2023-01-20 |
2024-07-25 |
Invetx, Inc. |
Bispecific binding agents for use in companion animals
|
WO2024158824A1
(en)
|
2023-01-23 |
2024-08-02 |
Yale University |
Antibody oligonucleotide conjugates
|
WO2024156759A1
(en)
|
2023-01-25 |
2024-08-02 |
F. Hoffmann-La Roche Ag |
Payload-bearing multispecific antibodies
|
WO2024156672A1
(en)
|
2023-01-25 |
2024-08-02 |
F. Hoffmann-La Roche Ag |
Antibodies binding to csf1r and cd3
|
WO2024163494A1
(en)
|
2023-01-31 |
2024-08-08 |
F. Hoffmann-La Roche Ag |
Methods and compositions for treating non-small cell lung cancer and triple-negative breast cancer
|
WO2024163009A1
(en)
|
2023-01-31 |
2024-08-08 |
Genentech, Inc. |
Methods and compositions for treating urothelial bladder cancer
|
WO2024165500A1
(en)
|
2023-02-06 |
2024-08-15 |
Merck Patent Gmbh |
Vhh-based nkp46 binders
|
WO2024165454A1
(en)
|
2023-02-06 |
2024-08-15 |
F. Hoffmann-La Roche Ag |
Combination therapy and uses thereof
|
WO2024167898A1
(en)
|
2023-02-07 |
2024-08-15 |
Go Therapeutics, Inc. |
ANTIBODY FUSION PROTEINS COMPRISING ANTI-GLYCO-MUC4 ANTIBODIES AND MIC PROTEIN α1-α2 DOMAINS, AND THEIR USES
|
WO2024168061A2
(en)
|
2023-02-07 |
2024-08-15 |
Ayan Therapeutics Inc. |
Antibody molecules binding to sars-cov-2
|
WO2024173607A2
(en)
|
2023-02-14 |
2024-08-22 |
Evolveimmune Therapeutics, Inc. |
Combination of bispecific antibodies and chimeric antigen receptor t cells for treatment
|
WO2024170756A1
(en)
|
2023-02-17 |
2024-08-22 |
Ablynx N.V. |
Polypeptides binding to the neonatal fc receptor
|
WO2024178056A1
(en)
|
2023-02-21 |
2024-08-29 |
Teneobio, Inc. |
C-kit binding proteins, chimeric antigen receptors, and uses thereof
|
US20240287186A1
(en)
|
2023-02-28 |
2024-08-29 |
Regeneron Pharmaceuticals, Inc. |
T cell activators and methods of use thereof
|
US20240309072A1
(en)
|
2023-02-28 |
2024-09-19 |
Regeneron Pharmaceuticals, Inc. |
Multivalent anti-spike protein binding molecules and uses thereof
|
WO2024183636A1
(en)
|
2023-03-03 |
2024-09-12 |
Beigene Switzerland Gmbh |
Cd16a antibodies and methods of use
|
WO2024183637A1
(en)
|
2023-03-03 |
2024-09-12 |
Beigene Switzerland Gmbh |
Muc1 antibodies and methods of use
|
WO2024183635A1
(en)
|
2023-03-03 |
2024-09-12 |
Beigene, Ltd. |
Muc1 and cd16a antibodies and methods of use
|
WO2024184811A1
(en)
|
2023-03-06 |
2024-09-12 |
Beigene Switzerland Gmbh |
Anti-cd3 multispecific antibodies and methods of use
|
WO2024184812A1
(en)
|
2023-03-06 |
2024-09-12 |
Beigene Switzerland Gmbh |
Anti-cldn6 antibodies and methods of use
|
WO2024184810A1
(en)
|
2023-03-06 |
2024-09-12 |
Beigene Switzerland Gmbh |
Anti-cldn6 and anti-cd3 multispecific antibodies and methods of use
|
WO2024184287A1
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