KR20220140568A - 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)에 대한 인간 단일클론 항체 - Google Patents

중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)에 대한 인간 단일클론 항체 Download PDF

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KR20220140568A
KR20220140568A KR1020227030973A KR20227030973A KR20220140568A KR 20220140568 A KR20220140568 A KR 20220140568A KR 1020227030973 A KR1020227030973 A KR 1020227030973A KR 20227030973 A KR20227030973 A KR 20227030973A KR 20220140568 A KR20220140568 A KR 20220140568A
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제임스 이. 크로
세스 조스트
로버트 카나한
파블로 길척
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벤더르빌트 유니버시티
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Abstract

본 개시내용은 SARS-CoV-2로 지정된 코로나바이러스에 결합하고 이를 중화시키는 항체 및 이의 사용 방법에 관한 것이다.

Description

중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)에 대한 인간 단일클론 항체
연방 자금에 관한 진술
본 발명은 미국 국방 고등 연구 계획국(DARPA)에서 수여한 HR0011-18-2-0001 및 미국 국립 알레르기 및 감염 질병 연구소/국립보건원에서 수여한 HHS 계약 75N93019C00074에 따라 정부 지원 하에 이루어졌다. 미국 정부는 본 발명에 대한 특정 권리를 가지고 있다.
우선권
본 출원은 2020년 2월 11일에 출원된 미국 가출원 제 62/972,877호 및 2020년 3월 25일에 출원된 제 62/994,627호에 대한 우선권의 이익을 주장하며, 상기 두 출원의 전문은 본 명세서에 참조로 포함된다.
서열 목록의 포함
"VBLTP0307WO1_ST25.txt"라는 파일에 포함된 서열목록은 4,165KB(Microsoft Windows®에서 측정)이고 2021년 2월 10일에 생성되었고 전자 제출로 제출되었으며 본 명세서에 참조로 포함된다.
배경
1. 개시의 분야
본 개시내용은 일반적으로 의학, 감염 질병 및 면역학 분야에 관한 것이다. 보다 구체적으로, 본 개시내용은 SARS-CoV-2로 지정된 신규 코로나바이러스에 결합하는 인간 항체 및 이의 사용 방법에 관한 것이다.
2. 배경
신종 코로나바이러스(SARS-CoV-2)의 에피데믹이 중국 본토에 발병하고 179개의 다른 국가 및 지역에서도 발병했다. 이는 중국 후베이성의 성도 우한에서 41명이 명확한 원인 없이 폐렴에 걸린 후 확인됐다. 코로나바이러스 질병 2019(COVID-19)로 지정된 급성 호흡기 질병을 일으키는 바이러스는 인간에서 인간으로 전파될 수 있다. 잠복기(노출시부터 증상 발현까지의 시간)는 0 내지 24일이며 평균 3 내지 5일이지만 이 기간 동안 및 회복 후에도 지속될 수 있다. 증상에는 발열, 기침, 호흡 곤란이 포함된다. 2020년 2월의 사망률 추정치는 확인된 사례의 2%로 입원이 필요한 환자들 중 더 높다.
2020년 2월 10일 현재 중국의 모든 성급 구역을 포함하여 40,627건(중증 6,495건)이 확인되었다. 더 많은 이들이 감염되었지만 발견되지 않았을 수 있다(특히 경증의 경우). 2020년 2월 10일 현재, 1월 9일 첫 번째로 확인된 사망 이후 이 바이러스로 인해 910명의 사망자가 발생했으며 3,323명이 회복되었다. 중국 외 지역의 제1 지역 전파는 베트남에서 가족 구성원 간에 발생했으며 가족을 포함하지 않은 제1 국제 전파는 1월 22일 독일에서 발생했다. 2월 1일 우한에서 온 한 남성이 사망한 필리핀은 중국 이외의 지역에서 첫 사망자가 발생한 국가이다. 2020년 2월 10일 현재, 이 바이러스로 인한 사망자 수는 2003년의 전 세계 SARS 발병을 능가했다.
2020년 2월 초 현재, 여러 백신 접근법과 항바이러스제가 조사되고 있지만 허가된 백신과 특정 치료법이 없다. 세계보건기구(WHO)는 이 발병을 국제적 공중보건 비상사태(PHEIC)로 선언했으며, 이는 바이러스가 의료 시스템이 취약한 국가로 확산될 경우 미칠 수 있는 영향을 기반으로 한다. 따라서 SARS-CoV-2의 생물학 및 병리학 및 이 바이러스에 대한 인간 면역 반응을 조사하는 것이 시급하게 요구된다.
따라서, 본 개시내용에 따르면, 대상체(subject)에서 SARS-CoV-2에 의한 COVID-19 감염을 검출하는 방법으로서, (a) 상기 대상체로부터의 샘플을 각각 표 3 및 표 4로부터의 클론-쌍(clone-paired) 중쇄 및 경쇄 CDR 서열을 갖는 항체 또는 항체 단편과 접촉시키는 단계; 및 (b) 상기 샘플에서 상기 항체 또는 항체 단편을 SARS-CoV-2 항원에 결합시킴으로써 상기 샘플에서 SARS-CoV-2를 검출하는 단계를 포함하는 방법이 제공된다. 샘플은 체액, 예컨대 혈액, 가래, 눈물, 타액, 점액 또는 혈청, 정액, 자궁경부 또는 질 분비물, 양수, 태반 조직, 소변, 삼출물, 여출물(transudate), 찰과표본(tissue scraping) 또는 분변일 수 있다. 검출은 ELISA, RIA, 측방 유동 분석(lateral flow assay) 또는 웨스턴 블롯(western blot)을 포함할 수 있다. 본 방법은 단계 (a) 및 (b)를 두 번째로 수행하고, 제1 분석과 비교하여 SARS-CoV-2 항원 수준의 변화를 결정하는 단계를 추가로 포함할 수 있다. 본 항체 또는 항체 단편은 표 1에 제시된 클론-쌍 가변 서열에 의해 인코딩(encoding)될 수 있다. 본 항체 또는 항체 단편은 표 1에 제시된 바와 같은 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성(identity)을 갖는 경쇄 및 중쇄 가변 서열 또는 표 1에 제시된 바와 같은 클론-쌍 서열에 대해 100% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩될 수 있다. 본 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열, 또는 표 2로부터의 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함할 수 있다. 본 항체 또는 항체 단편은 SARS-CoV-2 표면 스파이크 단백질(surface spike protein)에 결합할 수 있다. 본 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편일 수 있다. 대안적으로, 대안적으로, 이 단락의 임의의 실시양태는 서열번호 1 내지 9151에 존재하는 서열을 갖거나 이 서열에 의해 인코딩되는 항체를 사용할 수 있다.
또 다른 실시양태에서, SARS-CoV-2에 감염된 대상체를 치료하거나 SARS-CoV-2에 감염될 위험이 있는 대상체의 감염 가능성을 감소시키는 방법으로서, 상기 대상체에게 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 갖는 항체 또는 항체 단편을 전달하는 단계를 포함하는 방법이 제공된다. 본 항체 또는 항체 단편은 표 1에 제시된 바와 같은 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열 또는 표 1에 제시된 바와 같은 클론-쌍 서열에 대해 100% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩될 수 있다. 본 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열, 또는 표 2로부터의 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함할 수 있다. 본 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편일 수 있다. 본 항체는 키메라 항체(chimeric antibody) 또는 이중특이적 항체(bispecific antibody)일 수 있다. 본 항체는 LALA, LALA PG, N297, GASD/ALIE, DHS, YTE 또는 LS 돌연변이와 같은, 반감기를 증가시키고/거나 치료적 효능을 증가시키기 위해, Fc 상호작용을 변경(제거 또는 향상)하도록 돌연변이된 Fc 부분, 또는 글리칸의 효소적 또는 화학적 첨가 또는 제거 또는 정해진 글리코실화 패턴으로 조작된 세포주에서의 발현과 같은 FcR 상호작용을 변경(제거 또는 향상)하도록 변형된 글리칸을 포함하는 IgG, 또는 재조합 IgG 항체 또는 항체 단편일 수 있다. 본 항체 또는 항체 단편은 SARS-CoV-2 항원, 예컨대 표면 스파이크 단백질에 결합할 수 있다. 본 항체 또는 항체 단편은 감염 전 또는 감염 후에 투여될 수 있다. 대상체는 60세 이상이거나, 면역이 저하되었거나, 호흡기 및/또는 심혈관 장애를 앓고 있을 수 있다. 전달은 항체 또는 항체 단편 투여, 또는 항체 또는 항체 단편을 인코딩하는 RNA 또는 DNA 서열, 또는 벡터를 사용한 유전자 전달을 포함할 수 있다. 대안적으로, 이 단락의 임의의 실시양태는 서열번호 1 내지 9151에 존재하는 서열을 갖거나 이 서열에 의해 인코딩되는 항체를 사용할 수 있다.
또 다른 실시양태에서, 항체 또는 항체 단편은 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 특징으로 하는 단일클론 항체(monoclonal antibody)가 제공된다. 본 항체 또는 항체 단편은 표 1에 제시된 바와 같은 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열 또는 표 1에 제시된 바와 같은 클론-쌍 서열에 대해 100% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩될 수 있다. 본 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열, 또는 표 2로부터의 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함할 수 있다.
본 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편일 수 있다. 본 항체는 키메라 항체일 수 있거나, 이중특이적 항체이거나, 인트라바디(intrabody)일 수 있다. 본 항체는 LALA, LALA PG, N297, GASD/ALIE, DHS, YTE 또는 LS 돌연변이와 같은, 반감기를 증가시키고/거나 치료적 효능을 증가시키기 위해, Fc 상호작용을 변경(제거 또는 향상)하도록 돌연변이된 Fc 부분, 또는 글리칸의 효소적 또는 화학적 첨가 또는 제거 또는 정해진 글리코실화 패턴으로 조작된 세포주에서의 발현과 같은 FcR 상호작용을 변경(제거 또는 향상)하도록 변형된 글리칸을 포함하는 IgG, 또는 재조합 IgG 항체 또는 항체 단편일 수 있다. 본 항체 또는 항체 단편은 SARS-CoV-2 표면 스파이크 단백질에 결합할 수 있다. 대안적으로, 이 단락의 임의의 실시양태는 서열번호 1 내지 9151에 존재하는 서열을 갖거나 이 서열에 의해 인코딩되는 항체를 사용할 수 있다.
항체 또는 항체 단편을 인코딩하는 하이브리도마(hybridoma) 또는 조작된 세포로서, 본 항체 또는 항체 단편은 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 특징으로 한다. 본 항체 또는 항체 단편은 표 1에 제시된 바와 같은 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열 또는 표 1에 제시된 바와 같은 클론-쌍 서열에 대해 100% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩될 수 있다. 본 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열, 또는 표 2로부터의 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함할 수 있다. 본 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편일 수 있다. 본 항체는 키메라 항체, 이중특이적 항체, 또는 인트라바디일 수 있다. 본 항체는 LALA, LALA PG, N297, GASD/ALIE, DHS, YTE 또는 LS 돌연변이와 같은, 반감기를 증가시키고/거나 치료적 효능을 증가시키기 위해, Fc 상호작용을 변경(제거 또는 향상)하도록 돌연변이된 Fc 부분, 또는 글리칸의 효소적 또는 화학적 첨가 또는 제거 또는 정해진 글리코실화 패턴으로 조작된 세포주에서의 발현과 같은 FcR 상호작용을 변경(제거 또는 향상)하도록 변형된 글리칸을 포함하는 IgG, 또는 재조합 IgG 항체 또는 항체 단편일 수 있다. 본 항체 또는 항체 단편은 SARS-CoV-2 표면 스파이크 단백질에 결합할 수 있다. 대안적으로, 이 단락의 임의의 실시양태는 서열번호 1 내지 9151에 존재하는 서열을 갖거나 이 서열에 의해 인코딩되는 항체를 사용할 수 있다.
또 다른 실시양태에서, 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 특징으로 하는 하나 이상의 항체 또는 항체 단편을 포함하는 백신 제형이 제공된다. 적어도 하나의 상기 항체 또는 항체 단편은 표 1로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열, 표 1로부터의 클론-쌍 서열에 대해 적어도 70%, 80%, 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열 또는 표 1로부터의 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩될 수 있다. 적어도 하나의 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열을 포함할 수 있거나, 표 2로부터의 클론-쌍 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함할 수 있다. 적어도 하나의 상기 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편이다. 적어도 하나의 상기 항체는 키메라 항체, 이중특이적 항체 또는 인트라바디일 수 있다. 본 항체는 LALA, LALA PG, N297, GASD/ALIE, DHS YTE 또는 LS 돌연변이와 같은, 반감기를 증가시키고/거나 치료적 효능을 증가시키기 위해, Fc 상호작용을 변경(제거 또는 향상)하도록 돌연변이된 Fc 부분, 또는 글리칸의 효소적 또는 화학적 첨가 또는 제거 또는 정해진 글리코실화 패턴으로 조작된 세포주에서의 발현과 같은 FcR 상호작용을 변경(제거 또는 향상)하도록 변형된 글리칸을 포함하는 IgG, 또는 재조합 IgG 항체 또는 항체 단편일 수 있다. 본 항체 또는 항체 단편은 SARS-CoV-2 항원 표면 스파이크 단백질에 결합할 수 있다. 대안적으로, 이 단락의 임의의 실시양태는 서열번호 1 내지 9151에 존재하는 서열을 갖거나 이 서열에 의해 인코딩되는 항체를 사용할 수 있다.
추가의 실시양태에서, 본 명세서에 기재된 바와 같은 1차 항체 또는 항체 단편을 인코딩하는 하나 이상의 발현 벡터를 포함하는 백신 제형이 제공된다. 발현 벡터(들)는 신드비스 바이러스(Sindbis virus) 또는 VEE 벡터(들)일 수 있다. 백신은 바늘 주입, 제트 주입(jet injection) 또는 전기천공에 의한 전달을 위해 제형화될 수 있다. 백신 제형은 본 명세서에 기재된 바와 같은 별도의 항체 또는 항체 단편과 같은, 2차 항체 또는 항체 단편을 인코딩하는 하나 이상의 발현 벡터를 추가로 포함할 수 있다.
추가의 실시양태에서, 60세 이상의 대상체, 면역이 저하된 대상체 또는 SARS-CoV-2에 감염되었거나 감염될 위험이 있는 호흡기 및/또는 심혈관 장애를 앓고 있는 대상체의 건강을 보호하는 방법으로서, 상기 대상체에게 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 갖는 항체 또는 항체 단편을 전달하는 단계를 포함하는 방법이 제공된다. 본 항체 또는 항체 단편은 표 1에 제시된 바와 같은 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열 또는 표 1에 제시된 바와 같은 클론-쌍 서열에 대해 100% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩될 수 있다. 본 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열, 또는 표 2로부터의 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함할 수 있다. 본 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편일 수 있다. 본 항체는 LALA, LALA PG, N297, GASD/ALIE, DHS, YTE 또는 LS 돌연변이와 같은, 반감기를 증가시키고/거나 치료적 효능을 증가시키기 위해, Fc 상호작용을 변경(제거 또는 향상)하도록 돌연변이된 Fc 부분, 또는 글리칸의 효소적 또는 화학적 첨가 또는 제거 또는 정해진 글리코실화 패턴으로 조작된 세포주에서의 발현과 같은 FcR 상호작용을 변경(제거 또는 향상)하도록 변형된 글리칸을 포함하는 IgG, 또는 재조합 IgG 항체 또는 항체 단편일 수 있다. 본 항체는 키메라 항체 또는 이중특이적 항체일 수 있다. 상기 항체 또는 항체 단편은 감염 전 또는 감염 후에 투여될 수 있다. 본 항체 또는 항체 단편은 SARS-CoV-2 항원, 예컨대 표면 스파이크 단백질에 결합할 수 있다. 전달은 항체 또는 항체 단편 투여, 또는 항체 또는 항체 단편을 인코딩하는 RNA 또는 DNA 서열, 또는 벡터를 사용한 유전자 전달을 포함할 수 있다. 본 항체 또는 항체 단편은 비처리 대조군과 비교하여 대상체의 호흡을 개선할 수 있고/거나, 비처리 대조군과 비교하여 바이러스 함량을 감소시킬 수 있다. 대안적으로, 이 단락의 임의의 실시양태는 서열번호 1 내지 9151에 존재하는 서열을 갖거나 이 서열에 의해 인코딩되는 항체를 사용할 수 있다.
추가의 실시양태에서, SARS-CoV-2 표면 스파이크 단백질의 항원 완전성(antigenic integrity), 정확한 입체형태(conformation) 및/또는 정확한 서열을 결정하는 방법으로서, (a) 상기 항원을 포함하는 샘플을 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 갖는 1차 항체 또는 항체 단편과 접촉시키는 단계; 및 (b) 상기 항원에 대한 상기 1차 항체 또는 항체 단편의 검출가능한 결합에 의해 상기 항원의 항원 완전성, 정확한 입체형태 및/또는 정확한 서열을 결정하는 단계를 포함하는 방법이 제공된다. 샘플은 재조합에 의해 생산된 항원 또는 백신 제형 또는 백신 생산 뱃치(production batch)를 포함할 수 있다. 검출은 ELISA, RIA, 웨스턴 블롯, 표면 플라즈몬 공명 또는 생물층 간섭계를 사용하는 바이오센서, 또는 유세포 분석 염색(flow cytometry staining)을 포함할 수 있다. 1차 항체 또는 항체 단편은 표 1에 제시된 클론-쌍 가변 서열, 표 1에 제시된 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열, 또는 표 1에 제시된 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩될 수 있다. 1차 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열을 포함할 수 있거나, 표 2로부터의 클론-쌍 서열에 대해 적어도 70%, 80% 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함할 수 있거나, 표 2로부터의 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함할 수 있다. 1차 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편일 수 있다. 본 방법은 시간 경과에 따른 항원의 항원 안정성을 결정하기 위해 단계 (a) 및 (b)를 두 번째로 수행하는 단계를 추가로 포함할 수 있다. 대안적으로, 이 단락의 임의의 실시양태는 서열번호 1 내지 9151에 존재하는 서열을 갖거나 이 서열에 의해 인코딩되는 항체를 사용할 수 있다.
본 방법은 (c) 상기 항원을 포함하는 샘플을 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 갖는 2차 항체 또는 항체 단편과 접촉시키는 단계; 및 (d) 상기 항원에 대한 상기 2차 항체 또는 항체 단편의 검출가능한 결합에 의해 상기 항원의 항원 완전성을 결정하는 단계를 추가로 포함할 수 있다. 2차 항체 또는 항체 단편은 표 1에 제시된 클론-쌍 가변 서열, 표 1에 제시된 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열, 또는 표 1에 제시된 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩될 수 있다. 2차 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열을 포함할 수 있거나, 표 2로부터의 클론-쌍 서열에 대해 적어도 70%, 80% 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함할 수 있거나, 표 2로부터의 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함할 수 있다. 제2 1차 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편일 수 있다. 본 방법은 시간 경과에 따른 항원의 항원 안정성을 결정하기 위해 단계 (c) 및 (d)를 두 번째로 수행하는 단계를 추가로 포함할 수 있다. 대안적으로, 이 단락의 임의의 실시양태는 서열번호 1 내지 9151에 존재하는 서열을 갖거나 이 서열에 의해 인코딩되는 항체를 사용할 수 있다.
또한 인간 단일클론 항체 또는 항체 단편, 또는 하이브리도마 또는 이를 생산하는 조작된 세포로서, 상기 항체는 SARS-CoV-2 항원 표면 스파이크 단백질에 결합하는 인간 단일클론 항체 또는 항체 단편, 또는 하이브리도마 또는 이를 생성하는 조작된 세포가 제공된다.
청구범위 및/또는 명세서에서 " 내지 를 포함하는"이라는 용어와 함께 사용될 때 단수형("a" 또는 "an") 단어의 사용은 "하나"를 의미할 수 있지만, "하나 이상", "적어도 하나" 및 "하나 및 하나 초과"의 의미와도 일치한다. "약"이라는 단어는 명시된 숫자의 플러스 또는 마이너스 5%를 의미한다.
본 명세서에 기재된 임의의 방법 또는 조성물은 본 명세서에 기재된 임의의 다른 방법 또는 조성물과 관련하여 구현될 수 있음이 고려된다. 본 개시내용의 다른 목적, 특징 및 이점은 다음의 상세한 설명으로부터 명백해질 것이다. 그러나, 본 개시내용의 사상 및 범위 내의 다양한 변화 및 변형이 본 상세한 설명으로부터 당업자에게 명백할 것이므로, 상세한 설명 및 특정 예는 본 개시내용의 특정 실시양태를 나타내면서 단지 예시의 방식으로 제공됨이 이해되어야 한다.
상기에서 논의된 바와 같이, SARS-CoV-2는 활성 사례가 매일 증가하는 주요 건강 문제이다. 따라서 이 바이러스의 생물학과 바이러스에 대한 인간 면역 반응의 특성과 정도를 이해하는 것이 가장 중요하다. 본 발명자들은 SARS-CoV-2에 대한 인간 항체의 서열을 확인하였다. 이러한 항체의 서열 및 용도는 본 명세서에 개시되어 있다.
본 개시내용의 이들 및 다른 양상은 아래에서 상세히 기재된다.
I. 코로나바이러스 2019(SARS-CoV-2)
SARS-CoV-2는 호흡기 감염인 코로나바이러스 질병 2019(COVID-19)로 지정된 급성 호흡기 질병을 유발하는 전염성 바이러스이다. 이는 2019 내지 2020년 진행 중인 코로나바이러스 발병의 원인이며, 전세계적인 보건 비상사태이다. 게놈 시퀀싱 결과 양성 센스의 단일 가닥 RNA 코로나바이러스임이 밝혀졌다.
진행 중인 발병 동안, 이 바이러스는 종종 "코로나바이러스", "신종 코로나바이러스" 및 "우한 코로나바이러스"로 통용되는 용어로 언급되어 왔으며, WHO는 "SARS-CoV-2"라는 명칭을 권장한다. 국제바이러스분류위원회(ICTV)는 이 바이러스의 공식 명칭이 SARS-CoV-2라고 발표했다.
많은 초기 사례가 중국 우한 시의 대규모 해산물 및 동물 시장과 관련이 있으며, 이 바이러스는 인수공통전염병 유래로 생각된다. 이 바이러스와 다른 바이러스 샘플의 유전자 서열을 비교한 결과 SARS-CoV(79.5%) 및 박쥐 코로나바이러스(96%)와 유사한 것으로 나타났다. 이 발견은 천산갑과 같은 중간 숙주를 배제할 수는 없지만 궁극적인 유래는 박쥐일 가능성이 있다. 이 바이러스는 2개 이상의 코로나바이러스로 형성된 재조합 바이러스일 수 있다.
이 바이러스의 인간 대 인간 전염이 확인되었다. 코로나바이러스는 주로 밀접 접촉을 통해, 특히 약 6피트(1.8m) 범위 내에서 기침과 재채기의 호흡기 비말을 통해 전파된다. 바이러스 RNA는 감염된 환자의 분변 샘플에서도 발견되었다. 잠복기에도 바이러스가 전염될 수 있다.
식품용으로 판매된 동물은 원래 SARS-CoV-2의 저장소 또는 중간 숙주로 예상되었는데, 이는 바이러스에 감염된 것으로 처음 발견된 많은 개체가 화난 해산물 시장의 노동자였기 때문이다. 2003년 SARS가 발발했을 때 식용으로 살아있는 동물을 판매하는 시장이 또한 비난을 받았으며; 이러한 시장은 신종 병원체의 인큐베이터로 고려된다. 이 발병으로 중국에서 야생 동물의 거래와 소비가 일시적으로 금지되었다. 그러나 일부 연구자들은 화난 수산시장이 인간에게 바이러스를 전파하는 근원지가 아닐 수 있다고 제안했다.
충분한 수의 시퀀싱된 게놈으로, 바이러스 패밀리의 돌연변이 이력의 계통수를 재작제하는 것이 가능하다. 2003년 SARS 발병의 유래에 대한 연구는 대부분 말굽박쥐의 리놀로푸스(Rhinolophus) 속에서 유래한 SARS와 유사한 박쥐 코로나바이러스의 많은 발견으로 이어졌다. SARS-CoV-2는 이 범주의 SARS 연관 코로나바이러스에 속한다. 2015년과 2017년에 발표된 리놀로푸스 시니쿠스(Rhinolophus sinicus)의 두 게놈 서열은 SARS-CoV-2와 80%의 유사성을 보여준다. 리놀로푸스 아피니스(Rhinolophus affinis)의 세 번째 바이러스 게놈인 "RaTG13"은 Yunnan 지방에서 수집되었으며 SARS-CoV-2와 96% 유사하다.[28][29] 비교를 위해, 이러한 바이러스 간의 변이량은 H3N2 인간 인플루엔자 바이러스 균주에서 10년 동안 관찰된 돌연변이의 양과 유사하다.
SARS-CoV-2는 코로나바이러스로 알려진 광범위한 바이러스 패밀리에 속하며; "nCoV"는 보다 구체적인 명칭이 선택될 때까지 신종 코로나바이러스를 지칭하는데 사용되는 표준 용어이다. 이는 양성 센스 단일 가닥 RNA(+ssRNA) 바이러스이다. 다른 코로나바이러스는 일반적인 감기에서 중동호흡기증후군(MERS) 및 중증급성호흡기증후군(SARS)과 같은 보다 심각한 질병에 이르는 질병을 유발할 수 있다. 이는 인간을 감염시키는 것으로 알려진 코로나바이러스로서 229E, NL63, OC43, HKU1, MERS-CoV 및 SARS-CoV에 이어 7번째이다.
SARS-CoV와 마찬가지로 SARS-CoV-2는 사베코바이러스(Sarbecovirus) 아속(베타-CoV 계통 B)의 구성원이다. 이의 RNA 서열은 길이가 약 30,000개 염기이다. 1월 12일까지 SARS-CoV-2의 5개 게놈이 우한에서 단리되었고 중국 질병통제예방센터(CCDC) 및 기타 기관에서 보고했으며; 게놈의 수는 1월 26일까지 28개로 증가했다. 가장 초기의 GenBank 게놈을 제외하고 게놈은 GISAID에서 금수 조치를 받고 있다. 샘플에 대한 계통발생 분석은 Nextstrain을 통해 제공된다.
SARS-CoV-2 게놈의 공개는 이 바이러스의 스파이크(S) 단백질의 수용체 결합 단백질(RBD)에 대한 여러 단백질 모델링 실험으로 이어졌다. 결과는 S 단백질이 안지오텐신 전환 효소 2(ACE2) 수용체에 대한 충분한 친화도를 유지하여 이를 세포 진입 기전으로 사용할 수 있음을 시사한다. 1월 22일, 완전한 바이러스를 연구하는 중국의 그룹과 역유전학을 연구하는 미국의 그룹이 독립적이고 실험적으로 인간 ACE2를 SARS-CoV-2의 수용체로 입증했다.
가능한 프로테아제 억제제를 찾기 위해, ORF1a 폴리단백질로부터의 바이러스 3C-유사 프로테아제 M(pro)가 또한 약물 도킹 실험을 위해 모델링되었다. Innophore는 SARS 프로테아제를 기반으로 하는 두 가지 컴퓨터 모델을 생산했으며 중국 과학 아카데미는 재조합 SARS-CoV-2 프로테아제의 미공개 실험 구조를 생산했다. 또한 미시간 대학의 연구원들은 I-TASSER를 사용하여 SARS-CoV-2 게놈에서 모든 성숙한 펩타이드의 구조를 모델링했다.
알려진 최초의 인간 감염은 2019년 12월 초에 발생했다. SARS-CoV-2의 발병은 2019년 12월 중순에 중국 우한에서 처음 발견되었으며, 이는 감염된 단일 동물에서 유래한 것으로 보인다. 이후 이 바이러스는 중국의 모든 지역과 아시아, 유럽, 북미 및 오세아니아의 24개 이상의 다른 국가로 전파되었다. 이 모든 지역에서 이 바이러스의 인간 간 전파가 확인되었다. 2020년 1월 30일, SARS-CoV-2는 WHO에 의해 전세계적인 보건 비상사태로 지정되었다.
2020년 2월 10일(17:15 UTC) 기준으로 40,645명의 확인된 감염 사례가 있었고 그 중 40,196명이 중국 본토 내였다. 처음에는 중국 외 지역에서 발생한 거의 모든 사례가 우한에서 온 사람이거나 그 지역에서 여행한 사람과 직접 접촉한 사람에게서 발생했다. 나중에 여행자로부터 다른 나라로 전파되어 세계 여러 나라에서 전파되었다. 확인된 감염을 초래하거나 진단 가능한 SARS-CoV-2 급성 호흡기 질병으로 진행하는 감염의 비율은 아직 명확하지 않지만, 이 바이러스로 인한 총 사망자 수는 2020년 3월 25일 기준으로 19,000명 이상이었다.
이 바이러스의 기본 재생산 수(R-zero)는 1.4 내지 3.9로 추정된다. 즉, 확인되지 않은 경우 이 바이러스는 일반적으로 확립된 감염당 1.4 내지 3.9건의 새로운 사례를 발생시킨다. 이 바이러스는 최소 4명의 사슬을 따라 전파될 수 있다는 것이 확인되었다.
2020년 1월, 여러 조직과 기관에서 공개된 게놈을 기반으로 SARS-CoV-2에 대한 백신을 생성하는 작업을 개시했다. 중국에서는 중국 질병통제예방센터가 신종 코로나바이러스 백신을 개발하고 있다. 홍콩 대학은 또한 백신이 개발 중이라고 발표했다. Shanghai East Hospital은 또한 생명공학 회사인 Stemirna Therapeutics와 협력하여 백신을 개발하고 있다.
다른 곳에서, 생명공학 회사인 Moderna 및 Inovio Pharmaceuticals의 프로젝트 및 퀸즐랜드 대학의 다른 프로젝트를 포함하여 에피데믹 대비 혁신 연합(CEPI)에 의해 3개의 백신 프로젝트가 지원되고 있다. 미국 국립보건원(NIH)은 코로나바이러스 표면의 스파이크와 일치하는 RNA 백신을 생성하기 위해 Moderna와 협력하고 있고; 1상 임상 시험은 2020년 3월에 개시되었다. Inovio Pharmaceuticals는 2020년 여름에 백신에 대한 인체 시험을 수행하기를 희망하면서 중국 규제 당국의 승인을 가속화하기 위해 DNA 기반 백신을 개발하고 중국 회사와 협력하고 있다. 호주에서는 퀸즐랜드 대학이 바이러스 단백질을 유전자 변형하여 코로나바이러스를 모방하고 면역 반응을 자극하는 분자 클램프 백신의 가능성을 조사하고 있다.
독립적인 프로젝트에서, 캐나다 공중 보건국은 백신에 대한 작업을 개시하기 위해 서스캐처원 대학의 국제 백신 센터(VIDO-InterVac)에 허가를 부여했다. VIDO-InterVac은 2020년 3월에 생산 및 동물 실험을 개시하고 2021년에 인체 시험을 개시하는 것을 목표로 하고 있다. 런던의 임페리얼 대학 의약품 학부는 현재 동물에 대한 백신을 테스트하는 단계에 있다.
COVID-19 급성 호흡기 질병은 SARS-CoV-2에 의해 유발되는 바이러스성 호흡기 질병이다. 이는 2019 내지 2020년 우한 코로나바이러스 발병 당시 처음 발견되었다. 증상에는 발열, 마른 기침, 숨가쁨이 포함될 수 있다. 2020년 3월 현재 사용 가능한 특정 허가된 치료법은 없으며 증상을 완화하고 기능을 지원하는데 중점을 두고 있다.
감염된 사람들은 무증상이거나 발열, 기침, 숨가쁨과 같은 경증 내지 중증 증상이 있을 수 있다. 설사 또는 상부 호흡기 증상(예를 들어, 재채기, 콧물, 인후통)이 덜 빈번한다. 중증 감염의 경우 중증 폐렴, 다기관 부전 및 사망으로 진행될 수 있다. 노출 후 증상 발현까지의 시간은 세계보건기구에서는 2 내지 10일, 미국 질병통제예방센터(CDC)에서는 2 내지 14일로 추정하고 있다.
세계 보건 기구는 개인이 SARS-CoV-2 감염 가능성을 감소시키기 위해 취할 수 있는 예방 조치를 발표했다. 권장 사항은 이전에 다른 코로나바이러스에 대해 발표된 것과 유사하며 다음을 포함한다: 비누와 물로 손을 자주 씻고; 씻지 않은 손으로 눈, 코, 입을 만지지 않으며; 적절한 호흡기 위생을 실천한다.
WHO는 SARS-CoV-2에 대한 여러 테스트 프로토콜을 발표했다. 테스트는 실시간 역전사 중합효소 연쇄 반응(rRT-PCR)을 사용한다. 이 테스트는 호흡기 또는 혈액 샘플에서 수행할 수 있다. 결과는 일반적으로 몇 시간에서 며칠 이내에 제공된다.
질병에 대한 가능한 치료법에 대한 연구는 2020년 1월에 개시되었다. 중국 질병 통제 예방 센터는 1월 말에 코로나바이러스 관련 폐렴에서 기존 폐렴 치료법을 테스트하기 개시했다. RNA중합효소억제제인 렘데시비르(remdesivir)와 인터페론 베타(interferon beta)에 대한 조사도 있었다. 2020년 1월 말, 중국 의학 연구자들은 탐색 연구에서 세포 수준에서 SARS-CoV-2에 "상당히 우수한 억제 효과"가 있는 것으로 보이는 렘데시비르, 클로로퀸(chloroquine), 로피나비르(lopinavir)/리토나비르(ritonavir)에 대한 임상 시험을 개시할 의향을 표명했다. 2020년 2월 5일 중국은 질병에 대한 렘데시비르 사용에 대한 특허를 개시했다.
SARS-CoV-2 감염으로 인한 전체 사망률 및 이환율은 현재 발병에서 사례 치사율이 시간이 지남에 따라 변할 수 있고 진단 가능한 질병으로 진행되는 감염의 비율이 여전히 불분명하기 때문에 알려져 있지 않다. 그러나 SARS-CoV-2 급성 호흡기 질병에 대한 예비 연구에서는 치사율이 2%에서 3% 사이로 나타났으며, 2020년 1월 WHO는 사계 치사율이 약 3%라고 제시했다. 55명의 치명적인 사례에 대한 검토되지 않은 Imperial College의 인쇄 전 연구에 따르면 무증상 감염을 놓치면 조기 사망률 추정치가 너무 높을 수 있다. 그들은 평균 감염 치사율(감염자 중 사망률)을 무증상 보균자를 포함할 때 0.8%에서 후베이성에서 증상이 있는 사례만 포함할 때 18% 범위로 추정했다.
초기 데이터에 따르면 우한에서 병원에 입원한 처음 41명의 확인된 사례 중 13명(32%)이 집중 치료가 필요하고 6명(15%)이 사망했다. 사망한 사람들 중 많은 사람들이 처음에는 건강이 좋지 않아 면역계를 손상시키는 고혈압, 당뇨병 또는 심혈관 질병과 같은 병태를 보였다. 사망에 이르게 한 SARS-CoV-2 급성 호흡기 질병의 초기 사례에서 질병의 중앙값은 14일이었고 총 범위는 6일에서 41일인 것으로 나타났다.
II. 단일클론 항체 및 이의 생산
"단리된 항체"는 이의 천연 환경의 성분으로부터 분리 및/또는 회수된 것이다. 천연 환경의 오염 성분은 항체의 진단 또는 치료 용도를 방해하는 물질이며 효소, 호르몬 및 기타 단백질성 또는 비단백질성 용질을 포함할 수 있다. 특정 실시양태에서, 항체는 (1) 로우리(Lowry) 방법에 의해 측정된 95 중량% 초과, 가장 특히 99 중량% 초과의 항체; (2) 회전 컵 서열분석기를 사용하여 N-말단 또는 내부 아미노산 서열의 적어도 15개 잔기를 획득하기에 충분한 정도로; 또는 (3) 쿠마시 블루(Coomassie blue) 또는 음 염색을 사용하여 환원 또는 비환원 조건에서 SDS-PAGE에 의한 균질성으로 정제된다. 단리된 항체는 항체의 천연 환경의 적어도 하나의 성분이 존재하지 않을 것이기 때문에 재조합 세포내의 원위치의 항체를 포함한다. 그러나 일반적으로 단리된 항체는 적어도 하나의 정제 단계를 거쳐 제조된다.
기본 4개의 사슬 항체 단위는 2개의 동일한 경쇄(L) 및 2개의 동일한 중쇄(H)로 구성된 이종사량체 당단백질이다. IgM 항체는 J 사슬이라고 하는 추가 폴리펩타이드와 함께 5개의 기본 이종사량체 단위로 구성되어 있으므로 10개의 항원 결합 부위를 포함하고, 분비된 IgA 항체는 중합하여 J 사슬과 함께 기본 4개의 사슬 단위 2 내지 5개를 포함하는 다가 집합체를 형성할 수 있다. IgG의 경우 4개 사슬 단위는 일반적으로 약 150,000 달톤이다. 각 L 사슬은 하나의 공유 이황화 결합에 의해 H 사슬에 연결되어 있고, 두 개의 H 사슬은 H 사슬 이소형에 따라 하나 이상의 이황화 결합에 의해 서로 연결되어 있다. 각 H 및 L 사슬에는 규칙적으로 간격을 둔 사슬 내 이황화 가교가 있다. 각 H 사슬은 N-말단에 가변 영역(VH)과 알파 및 감마 사슬 각각에 대한 3개의 불변 도메인(CH) 및 뮤 및 이소형에 대한 4개의 CH 도메인을 갖는다. 각 L 사슬은 N-말단에 가변 영역(VL)이 있고 다른 쪽 말단에 불변 도메인(CL)이 있다. VL은 VH와 정렬되고 CL은 중쇄(CH1)의 제1 불변 도메인과 정렬된다. 특정 아미노산 잔기는 경쇄 및 중쇄 가변 영역 사이의 계면을 형성하는 것으로 여겨진다. VH와 VL의 쌍은 함께 단일 항원 결합 부위를 형성한다. 상이한 클래스의 항체의 구조 및 특성에 대해서는, 예를 들어 문헌[Basic and Clinical Immunology, 8th edition, Daniel P. Stites, Abba I. Terr and Tristram G. Parslow (eds.), Appleton & Lange, Norwalk, Conn., 1994, page 71, and Chapter 6]을 참조한다.
임의의 척추동물 종으로부터의 L 사슬은 불변 도메인(CL)의 아미노산 서열에 기반하여 카파 및 람다로 불리는 2개의 명확하게 구별되는 유형 중 하나로 지정될 수 있다. 중쇄(CH)의 불변 도메인의 아미노산 서열에 따라 면역글로불린은 다른 클래스 또는 이소형으로 분류될 수 있다. 면역글로불린에는 IgA, IgD, IgE, IgG 및 IgM의 5가지 클래스가 있으며 중쇄는 각각 알파, 델타, 엡실론, 감마 및 뮤로 지정된다. 감마 및 알파 클래스는 CH 서열 및 기능의 상대적으로 사소한 차이에 따라 하위 클래스로 더 나뉘며, 인간은 IgG1, IgG2, IgG3, IgG4, IgA1 및 IgA2 하위 클래스를 발현한다.
용어 "가변"은 V 도메인의 특정 절편이 항체 사이에서 서열이 광범위하게 상이하다는 사실을 지칭한다. V 도메인은 항원 결합을 매개하고 특정 항원에 대한 특정 항체의 특이성을 정의한다. 그러나 가변성은 가변 영역의 110개 아미노산 범위에 걸쳐 고르게 분포되지 않는다. 대신, V 영역은 각각 9 내지 12개 아미노산 길이인 "초가변 영역"이라고 하는 극도의 가변성의 더 짧은 영역으로 분리된 15 내지 30개 아미노산의 프레임워크 영역(FR)이라고 하는 상대적으로 불변의 가닥으로 구성된다. 천연 중쇄 및 경쇄의 가변 영역은 각각 4개의 FR을 포함하며, 주로 베타-시트 입체형태를 채택하고, 루프 연결을 형성하고 일부 경우에는 베타-시트 구조의 일부를 형성하는 3개의 초가변 영역에 의해 연결된다. 각 사슬의 초가변 영역은 FR에 의해 밀접하게 함께 유지되며 다른 사슬의 초가변 영역과 함께 항체의 항원 결합 부위 형성에 기여한다(문헌[Kabat et al., Sequences of Proteins of Immunological Interest, 5th Ed. Public Health Service, National Institutes of Health, Bethesda, Md. (1991)] 참조). 불변 도메인은 항체가 항원에 결합하는데 직접적으로 관여하지 않지만, 항체 의존성 세포독성(ADCC), 항체 의존성 세포 식세포작용(ADCP), 항체 의존성 호중구 식세포 작용(ADNP) 및 항체 의존성 보체 침착(ADCD)에 항체의 관여와 같은 다양한 효과기 기능을 나타낸다.
본 명세서에 사용되는 바와 같이, 용어 "초가변 영역"은 항원 결합을 담당하는 항체의 아미노산 잔기를 지칭한다. 초가변 영역은 일반적으로 "상보성 결정 영역" 또는 "CDR"로부터의 아미노산 잔기(예를 들어, 카밧 넘버링 시스템 문헌[Kabat et al., Sequences of Proteins of Immunological Interest, 5th Ed. Public Health Service, National Institutes of Health, Bethesda, Md. (1991)]에 따라 넘버링될 때 VL에서 대략 잔기 24-34(L1), 50-56(L2) 및 89-97(L3) 및 VH에서 대략 약 31-35(H1), 50-65(H2) 및 95-102(H3)); 및/또는 "초가변 루프"로부터의 잔기(예를 들어, 초티아 넘버링 시스템 문헌[Chothia and Lesk, J. Mol. Biol. 196:901-917 (1987)]에 따라 넘버링될 때 VL에서 잔기 24-34 (L1), 50-56 (L2) 및 89-97 (L3), VH에서 26-32 (H1), 52-56 (H2) 및 95-101 (H3)); 및/또는 "초가변 루프"/CDR로부터의 잔기(예를 들어, IMGT 넘버링 시스템 문헌[; Lefranc, M. P. et al. Nucl. Acids Res. 27:209-212 (1999), Ruiz, M. et al. Nucl. Acids Res. 28:219-221 (2000)]에 따라 넘버링될 때 VL에서 잔기 27-38 (L1), 56-65 (L2) 및 105-120 (L3) 및 VH에서 27-38 (H1), 56-65 (H2) 및 105-120 (H3))를 포함한다. 선택적으로 항체는 문헌[AHo; Honneger, A. and Plunkthun, A. J. Mol. Biol. 309:657-670 (2001)]에 따라 넘버링될 때 VL에서 다음 지점 28, 36 (L1), 63, 74-75 (L2) 및 123 (L3) 및 VsubH에서 28, 36 (H1), 63, 74-75 (H2) 및 123 (H3) 중 하나 이상에서 대칭 삽입을 나타낸다.
"생식계열 핵산 잔기"는 불변 또는 가변 영역을 인코딩하는 생식계열 유전자에서 천연적으로 발생하는 핵산 잔기를 의미한다. "생식계열 유전자"는 생식 세포(즉, 난자가 될 세포 또는 정자)에 존재하는 DNA이다. "생식계열 돌연변이"는 단일 세포 단계에서 생식 세포 또는 접합체에서 발생한 특정 DNA의 유전 가능한 변화를 지칭하며, 자손에게 전달되면 이러한 돌연변이가 신체의 모든 세포에 포함된다. 생식계열 돌연변이는 단일 체세포에서 획득되는 체세포 돌연변이와 상반된다. 일부 경우에, 가변 영역을 인코딩하는 생식계열 DNA 서열의 뉴클레오타이드가 돌연변이되고(즉, 체세포 돌연변이) 다른 뉴클레오타이드로 대체된다.
본 명세서에 사용되는 바와 같이, 용어 "단일클론 항체"는 실질적으로 균질한 항체 집단으로부터 획득된 항체를 지칭하며, 즉 집단을 구성하는 개별 항체는 소량으로 존재할 수 있는 가능한 천연 발생 돌연변이를 제외하고는 동일하다. 단일클론 항체는 단일 항원 부위에 대해 매우 특이적이다. 또한, 상이한 결정인자(에피토프)에 대해 지시된 상이한 항체를 포함하는 다클론 항체 제제와 달리, 각각의 단일클론 항체는 항원 상의 단일 결정인자에 대해 지시된다. 단일클론 항체는 특이성 외에도 다른 항체에 오염되지 않고 합성될 수 있다는 장점이 있다. 수식어 "단일클론"은 임의의 특정 방법에 의한 항체의 생산이 필요한 것으로 해석되어서는 안 된다. 예를 들어, 본 개시내용에 유용한 단일클론 항체는 문헌[Kohler et al., Nature, 256:495 (1975)]에 의해 처음으로 기재된 하이브리도마 방법론에 의해 제조될 수 있거나, 항원 특이적 B 세포의 단일 세포 분류, 감염 또는 면역화에 반응하는 항원 특이적 형질모세포, 또는 대량 분류된 항원 특이적 수집에서 단일 세포로부터 연결된 중쇄 및 경쇄의 포획 후에 박테리아, 진핵 동물 또는 식물 세포에서 재조합 DNA 방법을 사용하여 제조될 수 있다(예를 들어, 미국 특허 제 4,816,567호). "단일클론 항체"는 또한 예를 들어, 문헌[Clackson et al., Nature, 352:624-628 (1991) 및 Marks et al., J. Mol. Biol., 222:581-597 (1991)]에 기재된 기술을 사용하여 파지 항체 라이브러리로부터 단리될 수 있다.
A. 일반적인 방법
SARS-CoV-2에 결합하는 단일클론 항체는 여러 적용을 가질 것이라는 것을 이해할 것이다. 여기에는 SARS-CoV-2 감염을 검출 및 진단하고 이를 치료하는데 사용되는 진단 키트의 생산이 포함된다. 이러한 맥락에서, 이러한 항체를 진단 또는 치료제에 연결하거나, 경쟁 분석에서 포획 제제 또는 경쟁인자로 사용하거나, 추가 제제를 부착하지 않고 개별적으로 사용할 수 있다. 항체는 하기에 추가로 논의되는 바와 같이 돌연변이되거나 변형될 수 있다. 항체를 제조하고 특성화하는 방법은 당업계에 잘 알려져 있다(예를 들어, 문헌[Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory, 1988]; 미국 특허 제 4,196,265호 참조).
단일클론 항체(MAb)를 생성하는 방법은 일반적으로 다클론 항체를 제조하는 방법과 동일한 라인을 따라 개시된다. 이 두 가지 방법의 제1 단계는 적절한 숙주의 면역화 또는 이전의 천연 감염 또는 허가된 백신 또는 실험용 백신의 접종으로 면역성이 있는 대상체를 확인하는 것이다. 당업계에 잘 알려진 바와 같이, 면역화를 위한 소정의 조성물은 면역원성이 다양할 수 있다. 따라서 펩타이드 또는 폴리펩타이드 면역원을 담체에 연결함으로써 달성될 수 있는 바와 같이 숙주 면역계를 부스팅하는 것이 종종 필요하다. 예시적이고 바람직한 담체는 구멍삿갓조개 헤모시아닌(keyhole limpet hemocyanin)(KLH) 및 소 혈청 알부민(BSA)이다. 오브알부민, 마우스 혈청 알부민 또는 토끼 혈청 알부민과 같은 다른 알부민도 담체로 사용할 수 있다. 폴리펩타이드를 담체 단백질에 접합시키는 수단은 당업계에 잘 알려져 있으며, 글루타르알데하이드, m-말레이미도벤코일-N-하이드록시숙신이미드 에스테르, 카보디이미드 및 비스-비아조화 벤지딘을 포함한다. 또한 당업계에 잘 알려진 바와 같이, 특정 면역원 조성물의 면역원성은 애주번트로 알려진 면역 반응의 비특이적 자극제의 사용에 의해 향상될 수 있다. 동물에서 예시적이고 바람직한 애주번트는 완전 프로인트 애주번트(Freund's adjuvant)(사멸된 마이코박테리움 투버쿨로시스(Mycobacterium tuberculosis)을 포함하는 면역 반응의 비특이적 자극제), 불완전 프로인트 애주번트 및 수산화알루미늄 애주번트를 포함하고 인간에서는 명반, CpG, MFP59 및 면역자극 분자의 조합("애주번트 시스템, 예를 들어, AS01 또는 AS03)을 포함한다. 물리적 전달 시스템(예를 들어, 지질 나노입자 또는 금 생물체 비드)에서 DNA 또는 RNA 유전자로 전달되거나 바늘, 유전자 총, 경피적 전기천공 장치에 의해 전달되는 나노입자 백신 또는 유전자 인코딩 항원이 포함하여 SARS-CoV-2-특이적 B 세포를 유도하기 위한 추가적인 실험 형태의 접종이 가능하다. 항원 유전자는 또한 아데노바이러스, 아데노-연관 바이러스, 폭스바이러스, 헤르페스바이러스 또는 알파바이러스 레플리콘과 같은 복제 적격 또는 비적격 바이러스 벡터, 또는 대안적으로 바이러스 유사 입자에 의해 인코딩된 바와 같이 전달될 수 있다.
천연 병원체에 대한 인간 항체의 경우, 적절한 접근법은 질병에 걸린 것으로 진단된 인간 또는 병원체에 대한 보호 면역을 생성하거나 실험 백신의 안전성 또는 효능을 테스트하기 위해 백신 접종을 받은 인간과 같이 병원체에 노출된 대상체를 확인하는 것이다. 순환하는 항병원체 항체가 검출될 수 있고, 항체-양성 대상체로부터 B 세포를 인코딩하거나 생산하는 항체가 획득될 수 있다.
다클론 항체의 생산에 사용되는 면역원 조성물의 양은 면역화에 사용되는 동물 뿐만 아니라 면역원의 특성에 따라 다양하다. 다양한 경로를 사용하여 면역원을 투여할 수 있다(피하, 근육내, 피내, 정맥내 및 복강내). 다클론 항체의 생산은 면역화 후 다양한 지점에서 면역화된 동물의 혈액을 샘플링하여 모니터링할 수 있다. 두 번째 부스터 주사도 제공될 수 있다. 적절한 역가가 달성될 때까지 부스팅 및 역가 과정을 반복한다. 적절한 수준의 면역원성이 얻어지면, 면역화된 동물을 채혈하고 혈청을 단리 및 저장할 수 있고/거나 동물을 사용하여 MAb를 생성할 수 있다.
면역화 후, 항체를 생산할 가능성이 있는 체세포, 특히 B 림프구(B 세포)를 MAb 생성 프로토콜에 사용하기 위해 선택한다. 이러한 세포는 비장, 림프절, 편도선 또는 아데노이드 생검, 골수 흡인물 또는 생검, 폐 또는 위장관과 같은 점막 기관의 조직 생검 또는 순환 혈액에서 얻을 수 있다. 면역화된 동물 또는 면역 인간으로부터의 항체-생산 B 림프구는 일반적으로 면역화된 동물 또는 인간 또는 인간/마우스 키메라 세포와 동일한 종의 하나인 불멸성 골수종 세포의 세포와 융합된다. 하이브리도마 생산 융합 절차에 사용하기에 적합한 골수종 세포주는 바람직하게는 비항체 생산, 높은 융합 효율, 적절한 융합 세포(하이브리도마)의 성장만을 지원하는 특정 선택 배지에서의 성장을 불가능하게 하는 효소 결핍을 나타낸다. 당업자에게 공지된 바와 같이 다수의 골수종 세포 중 임의의 하나가 사용될 수 있다(문헌[Goding, pp. 65-66, 1986; Campbell, pp. 75-83, 1984]). HMMA2.5 세포 또는 MFP-2 세포는 이러한 세포의 특히 유용한 예이다.
항체-생산 비장 또는 림프절 세포와 골수종 세포의 혼성체를 생성하는 방법은 일반적으로 체세포와 골수종 세포를 2:1 비율로 혼합하는 단계를 포함하지만, 비율은 각각, 세포막의 융합을 촉진하는 제제 또는 제제들(화학적 또는 전기적)의 존재하에 약 20:1에서 약 1:1까지 다양할 수 있다. 일부 경우에는 초기 단계로 인간 B 세포를 엡스타인 바 바이러스(EBV)로 형질전환하면 B 세포의 크기가 증가하여 상대적으로 큰 크기의 골수종 세포와의 융합이 향상된다. EBV에 의한 형질전환 효율은 형질전환 배지에서 CpG 및 Chk2 억제제 약물을 사용함으로써 향상된다. 대안적으로, 인간 B 세포는 TNF 슈퍼패밀리의 유형 II 구성원인 인간 B 세포 활성화 인자(BAFF) 및 IL-21과 같은 추가 가용성 인자를 포함하는 배지에서 CD40 리간드(CD154)를 발현하는 형질감염된 세포주와의 공동 배양에 의해 활성화될 수 있다. 센다이 바이러스를 사용한 융합 방법은 문헌[Kohler and Milstein(1975; 1976)]에 의해 기재되었으며 폴리에틸렌 글리콜(PEG), 예를 들어 37%(v/v) PEG를 사용한 융합 방법은 문헌[Gefter et al. (1977)]에 의해 기재되었. 전기적으로 유도된 융합 방법의 사용도 적절하며(문헌[Goding, pp. 71-74, 1986]) 더 나은 효율성을 위한 과정가 있다(문헌[Yu et al., 2008]). 융합 절차는 일반적으로 약 1 x 10-6 내지 1 x 10-8의 저주파에서 실행 가능한 혼성체를 생산하지만 최적화된 절차를 사용하면 200분의 1에 가까운 융합 효율을 달성할 수 있다(문헌[Yu et al., 2008]). 그러나, 상대적으로 낮은 융합 효율은 문제가 되지 않는데, 생존 가능한 융합된 혼성체는 선택 배지에서 배양함으로써 모체의 주입된 세포(특히 일반적으로 무한히 계속 분열하는 주입된 골수종 세포)로부터 분화되기 때문이다. 선택 배지는 일반적으로 조직 배양 배지에서 뉴클레오타이드의 새로운 합성을 차단하는 제제를 포함하는 것이다. 예시적이고 바람직한 제제는 아미노프테린(aminopterin), 메토트렉세이트(methotrexate) 및 아자세린(azaserine)이다. 아미노프테린과 메토트렉세이트는 퓨린과 피리미딘의 새로운 합성을 차단하고, 아자세린은 퓨린 합성만 차단한다. 아미노프테린 또는 메토트렉세이트가 사용되는 경우, 배지는 뉴클레오타이드의 공급원으로서 하이포잔틴 및 티미딘으로 보충된다(HAT 배지). 아자세린이 사용되는 경우 배지에 하이포잔틴이 보충된다. B 세포 공급원이 EBV 형질전환 인간 B 세포주인 경우 골수종에 융합되지 않은 EBV 형질전환 세포주를 제거하기 위해 오우아바인(Ouabain)이 추가된다.
바람직한 선택 배지는 HAT 또는 오우아바인이 있는 HAT이다. 뉴클레오타이드 회수 경로를 작동할 수 있는 세포만이 HAT 배지에서 생존할 수 있다. 골수종 세포는 구제 경로의 핵심 효소, 예를 들어, 하이포크산틴 포스포리보실 트랜스퍼라제(HPRT)에 결함이 있으며 생존할 수 없다. B 세포는 이 경로를 작동할 수 있지만 배양 수명이 제한되어 있으며 일반적으로 약 2주 이내에 사멸한다. 따라서 선택 배지에서 생존할 수 있는 유일한 세포는 골수종과 B 세포에서 형성된 혼성체이다. 융합에 사용되는 B 세포의 공급원이 본 명세서에서와 같이 EBV 형질전환된 B 세포주인 경우, 오우아바인은 EBV 형질전환된 B 세포가 약물 사멸에 감응성이기 때문에 혼성체의 약물 선택에도 사용될 수 있지만 사용되는 골수종 파트너는 오우아바인 내성인 것으로 선택되었다.
배양은 특정 하이브리도마가 선택되는 하이브리도마 집단을 제공한다. 일반적으로 하이브리도마의 선택은 마이크로타이터 플레이트에서 단일 클론 희석에 의해 세포를 배양한 다음 적절한 반응성에 대해 개별 클론 상청액을 테스트(약 2 내지 3주 후)함으로써 수행된다. 분석은 방사면역분석, 효소 면역분석, 세포독성 분석, 플라크 분석 도트 면역결합 분석 등과 같이 감응성이고 간단하며 신속해야 한다. 그런 다음 선택된 하이브리도마를 연속 희석하거나 유세포 분석에 의해 단일 세포로 분류하고 개별 항체-생산 세포주로 클로닝하고, 이 클론은 mAb를 제공하기 위해 무한 증식될 수 있다. 세포주는 두 가지 기본 방식으로 MAb 생산을 위해 이용될 수 있다. 하이브리도마 샘플을 동물(예를 들어, 마우스)에 (종종 복강 내로) 주사할 수 있다. 선택적으로 동물은 주사 전에 탄화수소, 특히 프리스탄(테트라메틸펜타데칸)과 같은 오일로 프라이밍된다. 이와 같이 인간 하이브리도마를 사용하는 경우 종양거부반응을 방지하기 위해 SCID 마우스와 같은 면역저하 마우스를 주입하는 것이 최적이다. 주입된 동물은 융합된 세포 혼성체에 의해 생산된 특정 단일클론 항체를 분비하는 종양을 발생시킨다. 그런 다음 혈청 또는 복수액과 같은 동물의 체액을 두드려 MAb를 고농도로 제공할 수 있다. 개별 세포주는 또한 시험관내에서 배양될 수 있으며, MAb는 배양 배지로 천연적으로 분비되어, 고농도로 쉽게 획득될 수 있다. 대안적으로, 인간 하이브리도마 세포주는 시험관내에서 사용되어 세포 상청액에서 면역글로불린을 생산할 수 있다. 세포주는 고순도의 인간 단일클론 면역글로불린을 회수하는 능력을 최적화하기 위해 무혈청 배지에서의 성장에 적합할 수 있다.
두 수단에 의해 생산된 MAb는 적절한 경우 여과, 원심분리 및 FPLC 또는 친화도 크로마토그래피와 같은 다양한 크로마토그래피 방법을 사용하여 추가로 정제될 수 있다. 본 개시내용의 단일클론 항체의 단편은 펩신 또는 파파인과 같은 효소를 사용한 분해를 포함하는 방법 및/또는 화학적 환원에 의한 이황화 결합의 절단을 포함하는 방법에 의해 정제된 단일클론 항체로부터 획득될 수 있다. 대안적으로, 본 개시내용에 포함되는 단일클론 항체 단편은 자동화된 펩타이드 합성기를 사용하여 합성될 수 있다.
분자 클로닝 접근법을 사용하여 단일클론 항체를 생성할 수 있음이 또한 고려된다. 형질모세포 또는 활성화된 B 세포 마커로 인해 감염 또는 백신 접종에 반응하는 것으로 확인된 단일 B 세포 또는 대상 항원으로 표지된 기억 B 세포는 상자성 비드 선택 또는 유세포 분석 분류를 사용하여 물리적으로 분류될 수 있으며, 그런 다음 RNA는 RT-PCR에 의해 증폭된 단일 세포 및 항체 유전자로부터 단리될 수 있다. 다양한 단일 세포 RNA-seq 방법을 사용하여 단일 세포에서 항체 가변 유전자를 얻을 수 있다. 대안적으로, 항원 특이적 대량 분류 세포 집단은 중쇄 및 경쇄 앰플리콘의 물리적 연결 또는 소포로부터 중쇄 및 경쇄 유전자의 공통 바코드를 사용하여 단일 세포에서 회수된 미세소포 및 일치하는 중쇄 및 경쇄 가변 유전자로 분리될 수 있다. 단일 세포로부터 일치하는 중쇄 및 경쇄 유전자는 또한 세포당 하나의 바코드로 전사체를 표지하기 위한 바코드 및 RT-PCR 프라이머를 포함하는 세포 투과성 나노입자로 세포를 처리함으로써 항원 특이적 B 세포의 집단으로부터 얻을 수 있다. 항체 가변 유전자는 또한 하이브리도마 계통의 RNA 추출 및 RT-PCR에 의해 획득된 항체 유전자에 의해 단리되고 면역글로불린 발현 벡터에 클로닝될 수 있다. 대안적으로, 조합 면역글로불린 파지미드 라이브러리는 세포주로부터 단리된 RNA로부터 제조되고 적절한 항체를 발현하는 파지미드는 바이러스 항원을 사용하여 패닝함으로써 선택된다. 기존 하이브리도마 기술에 비해 이 접근법의 장점은 단일 라운드에서 약 104배 더 많은 항체를 생산하고 스크리닝할 수 있고 H 및 L 사슬 조합에 의해 새로운 특이성이 생성되어 적절한 항체를 찾을 가능성이 더 높아진다는 것이다.
본 개시내용에 유용한 항체의 생산을 교시하는 각각이 본 명세서에 참조로 포함되는 다른 미국 특허에는 조합 접근법을 사용한 키메라 항체의 생산을 기재하는 미국 특허 제 5,565,332호; 재조합 면역글로불린 제제를 기재하는 미국 특허 제 4,816,567호; 및 항체-치료제 접합체를 기재하는 미국 특허 제 4,867,973호가 포함된다.
B. 본 개시내용의 항체
본 개시내용에 따른 항체는 우선 그들의 결합 특이성에 의해 정의될 수 있다. 당업자는 당업자에게 잘 알려진 기술을 사용하여 소정의 항체의 결합 특이성/친화도를 평가함으로써 이러한 항체가 본 청구범위의 범위 내에 속하는지를 결정할 수 있다. 예를 들어, 소정의 항체가 결합하는 에피토프는 항원 분자(예를 들어, 도메인의 선형 에피토프) 내에 위치한 3개 이상(예를 들어, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20개)의 아미노산의 단일 인접 서열로 구성될 수 있다. 대안적으로, 에피토프는 항원 분자(예를 들어, 입체형태적 에피토프) 내에 위치한 복수의 비인접 아미노산(또는 아미노산 서열)으로 구성될 수 있다.
SARS-CoV-2 항원의 두 가지 주요 범주는 표면 스파이크(S) 단백질 및 내부 단백질, 특히 뉴클레오캡시드(N) 단백질이다. S 단백질에 대한 항체는 예방, 또는 치료, 또는 진단, 또는 백신 특성화에 유용할 것이다. S 단백질 항체는 SARS-CoV-2 S 단백질의 전장 엑토도메인에 결합하는 특정 항체(타이머와 같은 단량체 또는 올리고머로 표시됨; 임계 부위에서 프롤린의 도입("2P 돌연변이")과 같은 입체형태 안정화 돌연변이의 존재 또는 부재) 및 (a) 수용체 결합 도메인(RBD)에 결합하는 항-S 단백질 항체, (b) RBD 이외의 도메인에 결합하는 항-S 단백질 항체 에 의해 해당 단백질과의 추가의 결합 특이성을 가질 것이다. RBD 이외의 도메인에 결합하는 하위 집합 중 일부는 N 말단 도메인(NTD)에 결합하고 다른 일부는 NTD 또는 RBD 이외의 에피토프에 결합하고, (c) S 단백질 항체는 추가로 수용체 결합을 차단하지 않는 다른 것들과 SARS-CoV-2 S 단백질의 수용체인 인간 안지오텐신 전환 효소 2(hACE2)에 대한 결합을 차단함으로써 SARS-CoV-2를 중화시키는 것으로 나타날 수 있다. 마지막으로, 항체는 SARS-CoV-2 S 단백질 및 SARS-CoV, MERS-CoV, HCoV-229E, HCoV-OC43, HCoV-NL63 및/또는 HCoV-HKU1과 같은 다른 코로나바이러스의 S 단백질 둘 모두와 교차 반응할 수 있고, SARS-CoV-2와 이러한 다른 코로나바이러스 둘 모두를 교차 중화할 수 있다.
또 다른 특이성은 주로 진단 용도를 가질 N 항체(또는 다른 내부 표적)에 결합하는 항체일 것이다. 예를 들어, SARS-CoV-2를 특이적으로 인식하거나 SARS-CoV-2 및 SARS-CoV, MERS-CoV, HCoV-229E, HCoV-OC43, HCoV-NL63 및/또는 HCoV-HKU1와 같은 기타 코로나바이러스를 교차 반응적으로 인식하는 SARS-CoV-2의 N 또는 기타 내부 단백질에 대한 항체.
당업자에게 공지된 다양한 기술을 사용하여 항체가 폴리펩타이드 또는 단백질 내에서 "하나 이상의 아미노산과 상호작용"하는지를 결정할 수 있다. 예시적인 기술은 예를 들어 문헌[Antibodies, Harlow and Lane(Cold Spring Harbor Press, Cold Spring Harbor, N.Y.)]에 기재된 것과 같은 통상적인 교차 차단 분석을 포함한다. 교차 차단은 ELISA, 생물층 간섭계 또는 표면 플라즈몬 공명과 같은 다양한 결합 분석에서 측정될 수 있다. 다른 방법에는 알라닌 스캐닝 돌연변이 분석, 펩타이드 블롯 분석(문헌[Reineke, Methods Mol. Biol. 248: 443-63, 2004]), 펩타이드 절단 분석, 단일 입자 재구성을 사용한 고분해능 전자 현미경 기술, cryoEM 또는 단층 촬영, 결정학 연구 및 NMR 분석이 포함된다. 또한 에피토프 절제, 에피토프 추출 및 항원의 화학적 변형과 같은 방법을 사용할 수 있다(문헌[Tomer Prot. Sci. 9: 487-496, 2000]). 항체가 상호작용하는 폴리펩타이드 내의 아미노산을 확인하는데 사용할 수 있는 또 다른 방법은 질량 분석법에 의해 검출되는 수소/중수소 교환이다. 일반적으로 수소/중수소 교환 방법은 해당 단백질을 중수소로 표지한 후 항체가 중수소로 표지된 단백질에 결합하는 단계를 포함한다. 다음으로, 단백질/항체 복합체는 물로 옮겨지고 항체 복합체에 의해 보호되는 아미노산 내의 교환 가능한 양성자는 계면의 일부가 아닌 아미노산 내의 교환 가능한 양성자보다 더 느린 속도로 중수소에서 수소로 역교환된다. 결과적으로 단백질/항체 계면의 일부를 형성하는 아미노산은 중수소를 보유할 수 있으므로 계면에 포함되지 않은 아미노산에 비해 상대적으로 더 높은 질량을 나타낼 수 있다. 항체의 해리 후, 표적 단백질은 프로테아제 절단 및 질량 분석을 거쳐 항체가 상호작용하는 특정 아미노산에 상응하는 중수소 표지된 잔기를 노출시킨다. 예를 들어, 문헌Ehring, Analytical Biochemistry 267: 252-259 (1999); Engen and Smith, Anal. Chem. 73: 256A-265A (2001)]을 참조한다. 항체가 SARS-CoV-2를 중화할 때, 항체 탈출 돌연변이 변이체 유기체는 시험관내 또는 동물 모델에서 고농도의 항체 존재하에 SARS-CoV-2를 증식시켜 단리될 수 있다. 항체가 표적화하는 항원을 인코딩하는 SARS-CoV-2 유전자의 서열 분석은 항체 탈출을 부여하는 돌연변이(들)를 밝혀냈고, 이는 에피토프의 잔기를 나타내거나 에피토프의 구조에 알로스테릭하게 영향을 미친다.
용어 "에피토프"는 B 및/또는 T 세포가 반응하는 항원 상의 부위를 지칭한다. B-세포 에피토프는 단백질의 3차 접힘에 의해 병치된 인접 아미노산 또는 비인접 아미노산 모두로부터 형성될 수 있다. 인접 아미노산으로부터 형성된 에피토프는 일반적으로 변성 용매에 노출되면 유지되고, 3차 접힘에 의해 형성된 에피토프는 일반적으로 변성 용매로 처리하면 손실된다. 에피토프는 통상적으로 고유한 공간적 입체형태로 적어도 3개, 보다 일반적으로 적어도 5개 또는 8 내지 10개의 아미노산을 포함한다.
항원 구조 기반 항체 프로파일링(ASAP)으로도 알려진 변형 보조 프로파일링(MAP)은 화학적으로 또는 효소적으로 변형된 항원 표면에 대한 각각의 항체의 결합 프로파일의 유사성에 따라 동일한 항원에 대해 지시된 다수의 단일클론 항체(mAb)를 분류하는 방법이다(미국 특허 공개 제 2004/0101920호 참조, 상기 문헌의 전문은 본 명세서에 참조로 구체적으로 포함됨). 각 범주는 다른 범주로 나타나는 에피토프와 뚜렷이 다르거나 부분적으로 겹치는 고유한 에피토프를 반영할 수 있다. 이 기술을 사용하면 유전적으로 동일한 항체를 신속하게 필터링할 수 있으므로 유전적으로 구별되는 항체에 특성화를 집중할 수 있다. 하이브리도마 스크리닝에 적용할 때 MAP는 적절한 특성을 갖는 mAb를 생산하는 희귀 하이브리도마 클론의 확인을 용이하게 할 수 있다. MAP를 사용하여 본 개시내용의 항체를 상이한 에피토프에 결합하는 항체의 그룹으로 분류할 수 있다.
본 개시내용은 동일한 에피토프, 또는 에피토프의 일부에 결합할 수 있는 항체를 포함한다. 마찬가지로, 본 개시내용은 또한 표적 또는 이의 단편에 대한 결합에 대해 본 명세서에 기재된 임의의 특정 예시적인 항체와 경쟁하는 항체를 포함한다. 당업계에 공지된 통상적인 방법을 사용하여 항체가 참조 항체와 동일한 에피토프에 결합하는지 또는 결합에 대해 경쟁하는지를 쉽게 결정할 수 있다. 예를 들어, 테스트 항체가 참조와 동일한 에피토프에 결합하는지 확인하기 위해 참조 항체를 포화 조건에서 표적에 결합하도록 할 수 있다. 다음으로, 표적 분자에 결합하는 테스트 항체의 능력이 평가된다. 테스트 항체가 참조 항체와의 포화 결합 후 표적 분자에 결합할 수 있다면, 테스트 항체가 참조 항체와 다른 에피토프에 결합한다고 결론지을 수 있다. 반면에, 테스트 항체가 참조 항체와의 포화 결합 후 표적 분자에 결합할 수 없는 경우, 테스트 항체는 참조 항체에 의해 결합된 에피토프와 동일한 에피토프에 결합할 수 있다.
항체가 참조 항-SARS-CoV-2 항체와 결합에 대해 경쟁하는지 결정하기 위해, 상기 기재된 결합 방법론은 2가지 방향으로 수행된다: 제1 방향에서, 포화 조건 하에서 참조 항체가 SARSCoV-2 항원에 결합하도록 허용된 후, SARS-CoV-2 분자에 대한 테스트 항체의 결합을 평가한다. 두 번째 방향에서, 테스트 항체는 포화 조건 하에 SARS-CoV-2 항원 분자에 결합하도록 허용된 후 SARS-CoV-2 분자에 대한 참조 항체의 결합을 평가한다. 두 방향 모두에서 1차(포화) 항체만 SARS-CoV-2에 결합할 수 있는 경우 테스트 항체와 참조 항체가 SARS-CoV-2에 결합하기 위해 경쟁하는 것으로 결론지어진다. 당업자에 의해 이해되는 바와 같이, 참조 항체와 결합을 위해 경쟁하는 항체는 반드시 참조 항체와 동일한 에피토프에 결합할 필요는 없지만 중첩 또는 인접한 에피토프와 결합함으로써 참조 항체의 결합을 입체적으로 차단할 수 있다.
2개의 항체는 각각이 항원에 대한 다른 항체의 결합을 경쟁적으로 억제(차단)하는 경우 동일하거나 중첩되는 에피토프에 결합한다. 즉, 한 항체의 1-, 5-, 10-, 20- 또는 100배 과량은 다른 항체의 결합을 경쟁적 결합 분석에서 측정할 때 적어도 50%, 바람직하게는 75%, 90% 또는 심지어 99%까지 억제한다(예를 들어, 문헌[Junghans et al., Cancer Res. 1990 50:1495-1502] 참조). 대안적으로, 한 항체의 결합을 감소 또는 제거하는 필수적으로 항원 내의 모든 아미노산 돌연변이가 다른 항체의 결합을 감소 또는 제거하는 경우 2개의 항체는 동일한 에피토프를 갖는다. 한 항체의 결합을 감소 또는 제거하는 일부 아미노산 돌연변이가 다른 항체의 결합을 감소 또는 제거하는 경우 두 항체는 중첩 에피토프를 갖는다.
그 다음, 관찰된 테스트 항체의 결합 부재가 참조 항체와 동일한 에피토프에 대한 결합 때문인지 또는 입체 차단(또는 다른 현상)이 관찰된 결합의 부재에 관여하는 지를 확인하기 위해 추가의 통상적인 실험(예를 들어, 펩타이드 돌연변이 및 결합 분석)을 수행할 수 있다. 이러한 종류의 실험은 ELISA, RIA, 표면 플라즈몬 공명, 유세포 분석 또는 당업계에서 이용 가능한 임의의 다른 정량적 또는 정성적 항체 결합 분석을 사용하여 수행할 수 있다. EM 또는 결정학을 사용한 구조 연구에 의해 또한 결합을 위해 경쟁하는 두 항체가 동일한 에피토프를 인식하는지를 입증할 수 있다.
또 다른 양상에서, 각각 표 3 및 표 4에 예시된 바와 같은 중쇄 및 경쇄로부터 클론-쌍 CDR을 갖는 단일클론 항체가 제공된다. 이러한 항체는 본 명세서에 기재된 방법을 사용하여 실시예 섹션에서 하기 논의된 클론에 의해 생산될 수 있다.
또 다른 양상에서, 항체는 추가의 "프레임워크" 영역을 포함하는 가변 서열에 의해 정의될 수 있다. 또한, 항체 서열은 선택적으로 하기에 더 상세히 논의되는 방법을 사용하여 이들 서열과 달라질 수 있다. 예를 들어, 핵산 서열은 (a) 가변 영역이 경쇄 및 중쇄의 불변 도메인으로부터 분리될 수 있거나, (b) 핵산이 위에 제시된 것과 다를 수 있지만, 그에 의해 인코딩된 잔기에 영향을 미치지 않거나, (c) 핵산은 소정의 백분율, 예를 들어, 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% 또는 99% 상동성에 의해 위에 제시된 것과 다를 수 있거나, (d) 핵산은 약 50℃ 내지 약 70℃의 온도에서 약 0.02M 내지 약 0.15M NaCl에 의해 제공되는 것과 같은 저염 및/또는 고온 조건으로 예시되는 바와 같이 높은 엄격성 조건 하에서 혼성화하는 능력으로 인해 위에서 제시된 것과 다를 수 있거나, (e) 아미노산은 소정의 백분율, 예를 들어, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% 또는 99% 상동성에 의해 위에서 제시된 것과 다를 수 있거나, (f) 아미노산은 보존적 치환(하기에 논의됨)을 허용하여 위에 제시된 것과 다를 수 있다는 점에서 위에 제시된 것과 다를 수 있다. 상기 각각은 핵산 서열 및 아미노산 서열에 적용된다.
폴리뉴클레오타이드 및 폴리펩타이드 서열을 비교할 때, 하기 기재된 바와 같이 최대 일치성을 위해 정렬될 때 두 서열의 뉴클레오타이드 또는 아미노산의 서열이 동일한 경우 두 서열은 "동일한" 것이라고 한다. 두 서열 간의 비교는 일반적으로 서열 유사성의 국소 영역을 확인하고 비교하기 위해 비교 창을 통해 서열을 비교함으로써 수행된다. 본 명세서에 사용되는 바와 같이, "비교 창"은 두 서열이 최적으로 정렬된 후 서열이 동일한 수의 인접 위치의 참조 서열과 비교될 수 있는 적어도 약 20개의 인접 위치, 일반적으로 30 내지 약 75, 40 내지 약 50개의 절편을 지칭한다.
비교를 위한 서열의 최적 정렬은 기본 매개변수를 사용하여 생물정보학 소프트웨어의 Lasergene 산물군(DNASTAR, Inc., Madison, Wis.)에서 Megalign 프로그램을 사용하여 수행될 수 있다. 이 프로그램은 다음 참조 문헌에 기재된 다수의 정렬 방식을 구현한다: 문헌[Dayhoff, M. O. (1978) A model of evolutionary change in proteins--Matrices for detecting distant relationships. In Dayhoff, M. O. (ed.) Atlas of Protein Sequence and Structure, National Biomedical Research Foundation, Washington D.C. Vol. 5, Suppl. 3, pp. 345-358; Hein J. (1990) Unified Approach to Alignment and Phylogeny pp. 626-645 Methods in Enzymology vol. 183, Academic Press, Inc., San Diego, Calif.; Higgins, D. G. and Sharp, P. M. (1989) CABIOS 5:151-153; Myers, E. W. and Muller W. (1988) CABIOS 4:11-17; Robinson, E. D. (1971) Comb. Theor 11:105; Santou, N. Nes, M. (1987) Mol. Biol. Evol. 4:406-425; Sneath, P. H. A. and Sokal, R. R. (1973) Numerical Taxonomy--the Principles and Practice of Numerical Taxonomy, Freeman Press, San Francisco, Calif.; Wilbur, W. J. and Lipman, D. J. (1983) Proc. Natl. Acad., Sci. USA 80:726-730].
대안적으로, 비교를 위한 서열의 최적 정렬은 문헌[Smith and Waterman (1981) Add. APL. Math 2:482]의 국소 확인 알고리즘, 문헌[Needleman and Wunsch (1970) J. Mol. Biol. 48:443]의 확인 정렬 알고리즘, 문헌[Pearson and Lipman (1988) Proc. Natl. Acad. Sci. USA 85: 2444]의 유사성 방법의 검색, 이러한 알고리즘의 컴퓨터 구현(Wisconsin Genetics Software Package, Genetics Computer Group (GCG), 575 Science Dr., Madison, Wis.의 GAP, BESTFIT, BLAST, FASTA 및 TFASTA) 또는 검사에 의해 수행될 수 있다.
서열 동일성 및 서열 유사성 퍼센트를 결정하는데 적합한 알고리즘의 한 특정 예는 각각 문헌[Altschul et al. (1977) Nucl. Acids Res. 25:3389-3402 및 Altschul et al. (1990) J. Mol. Biol. 215:403-410]에 기재되어 있는 BLAST 및 BLAST 2.0 알고리즘이다. BLAST 및 BLAST 2.0은, 예를 들어, 본 개시내용의 폴리뉴클레오타이드 및 폴리펩타이드에 대한 서열 동일성 퍼센트를 결정하기 위해 본 명세서에 기재된 매개변수와 함께 사용될 수 있다. BLAST 분석을 수행하기 위한 소프트웨어는 미국 국립 생명 공학 정보 센터를 통해 공개적으로 제공된다. 항체 서열의 재배열된 특성과 각 유전자의 가변 길이는 단일 항체 서열에 대한 다회의 BLAST 검색이 필요하다. 또한 서로 다른 유전자를 수동으로 조립하는 것은 어렵고 오류가 발생하기 쉽다. 서열 분석 도구 IgBLAST(전세계 웹 ncbi.nlm.nih.gov/igblast/)는 생식계열 V, D 및 J 유전자에 대한 일치, 재배열 접합부의 세부사항, Ig V 도메인 프레임워크 영역의 묘사 및 상보성 결정 영역을 확인한다. IgBLAST는 뉴클레오타이드 또는 단백질 서열을 분석할 수 있고 뱃치로 서열을 처리할 수 있으며 생식계열 유전자 데이터베이스 및 기타 서열 데이터베이스에 대한 검색을 동시에 가능하게 하여 가장 일치하는 생식계열 V 유전자가 누락될 가능성을 최소화한다.
하나의 예시적인 예에서, 누적 점수는 뉴클레오타이드 서열에 대해 매개변수 M(일치하는 잔기 쌍에 대한 보상 점수; 항상 >0) 및 N(일치하지 않는 잔기에 대한 페널티 점수; 항상 <0)을 사용하여 계산될 수 있다. 다음과 같은 경우 각 방향의 히트 단어 연장이 중단된다: 누적 정렬 점수가 최대 달성 값에서 수량 X만큼 떨어진 경우; 하나 이상의 음수 점수 잔기 정렬의 누적으로 인해 누적 점수가 0 이하가 된 경우; 또는 서열의 말단에 도달한 경우. BLAST 알고리즘 매개변수 W, T 및 X는 정렬의 감도와 속도를 결정한다. BLASTN 프로그램(뉴클레오타이드 서열용)은 기본값으로 단어 길이(W) 11, 기대값(E) 10, BLOSUM62 점수 매트릭스(문헌[Henikoff and Henikoff(1989) Proc. Natl. Acad. Sci. USA 89:10915] 참조) 정렬, (B) 50, 기대치(E) 10, M=5, N=-4 및 두 가닥의 비교를 사용한다.
아미노산 서열의 경우, 점수 매트릭스를 사용하여 누적 점수를 계산할 수 있다. 다음과 같은 경우 각 방향의 히트 단어 연장이 중단된다: 누적 정렬 점수가 최대 달성 값에서 수량 X만큼 떨어진 경우; 하나 이상의 음수 점수 잔기 정렬의 누적으로 인해 누적 점수가 0 이하가 된 경우; 또는 서열의 말단에 도달한 경우. BLAST 알고리즘 매개변수 W, T 및 X는 정렬의 감도와 속도를 결정한다.
일 접근법에서, "서열 동일성 백분율"은 적어도 20개의 위치의 비교 창에 걸쳐 2개의 최적으로 정렬된 서열을 비교함으로써 결정되며, 비교 창에서 폴리뉴클레오타이드 또는 폴리펩타이드 서열의 일부는 두 서열의 최적 정렬을 위한 참조 서열(추가 또는 결실을 포함하지 않음)과 비교하여 20 퍼센트 이하, 일반적으로 5 내지 15 퍼센트, 또는 10 내지 12 퍼센트의 추가 또는 결실(즉, 갭)을 포함할 수 있다. 백분율은 일치된 위치의 수를 산출하기 위해 두 서열에서 동일한 핵산 염기 또는 아미노산 잔기가 발생하는 위치의 수를 결정하고, 일치된 위치의 수를 참조 서열의 총 위치 수(즉, 창 크기)로 나누고 결과에 100을 곱하여 서열 동일성의 백분율을 산출함으로써 계산된다.
항체를 정의하는 또 다른 방법은 하기에 기재된 항체 및 이의 항원 결합 단편 중 임의의 것의 "유도체"로서의 것이다. 용어 "유도체"는 항원에 면역특이적으로 결합하지만 "모체"(또는 야생형) 분자에 비해 1, 2, 3, 4, 5개 이상의 아미노산 치환, 추가, 결실 또는 변형을 포함하는 항체 또는 이의 항원 결합 단편을 지칭한다. 이러한 아미노산 치환 또는 추가는 천연 발생(즉, DNA 인코딩) 또는 비천연 발생 아미노산 잔기를 도입할 수 있다. 용어 "유도체"는 예를 들어, 향상되거나 손상된 효과기 또는 결합 특성을 나타내는 변이체 Fc 영역을 갖는 항체 등을 형성하기 위해 변경된 CH1, 힌지, CH2, CH3 또는 CH4 영역을 갖는 변이체로서 포함한다. 용어 "유도체"는 비-아미노산 변형, 예를 들어 글리코실화(예를 들어, 변경된 만노스, 2-N-아세틸글루코사민, 갈락토스, 푸코스, 글루코스, 시알산, 5-N-아세틸뉴라민산, 5-글리콜뉴라민산 등 함량을 가짐), 아세틸화, 페길화, 인산화, 아미드화, 공지된 보호/차단기에 의해 유도체화, 단백질 분해 절단, 세포 리간드 또는 다른 단백질에 연결되는 등일 수 있는 아미노산을 추가로 포함한다. 일부 실시양태에서, 변경된 탄수화물 변형은 다음 중 하나 이상을 조절한다: 항체의 가용화, 항체의 세포하 수송 및 분비 촉진, 항체 조립 촉진, 입체형태적 완전성 및 항체 매개 효과기 기능. 특정 실시양태에서, 변경된 탄수화물 변형은 탄수화물 변형이 부재하는 항체에 비해 항체 매개 효과기 기능을 향상시킨다. 변경된 항체 매개 효과기 기능을 유도하는 탄수화물 변형은 당업계에 잘 알려져 있다(예를 들어, 문헌[Shields, R. L. et al. (2002) "Lack Of Fucose On Human IgG N-Linked Oligosaccharide Improves Binding To Human Fcgamma RIII And Antibody-Dependent Cellular Toxicity," J. Biol. Chem. 277(30): 26733-26740; Davies J. et al. (2001) "Expression Of GnTIII In A Recombinant Anti-CD20 CHO Production Cell Line: Expression Of Antibodies With Altered Glycoforms Leads To An Increase In ADCC Through Higher Affinity For FC Gamma RIII," Biotechnology & Bioengineering 74(4): 288-294)] 참조). 탄수화물 함량을 변경하는 방법은 당업자에게 알려져 있으며, 예를 들어, 문헌[Wallick, S. C. et al. (1988) "Glycosylation Of A VH Residue Of A Monoclonal Antibody Against Alpha (1----6) Dextran Increases Its Affinity For Antigen," J. Exp. Med. 168(3): 1099-1109; Tao, M. H. et al. (1989) "Studies Of Aglycosylated Chimeric Mouse-Human IgG. Role of Carbohydrate in The Structure And Effector Functions Mediated By The Human IgG Constant Region," J. Immunol. 143(8): 2595-2601; Routledge, E. G. et al. (1995) "The Effect of Aglycosylation on The Immunogenicity of A Humanized Therapeutic CD3 Monoclonal Antibody," Transplantation 60(8):847-53; Elliott, S. et al. (2003) "Enhancement Of Therapeutic Protein In Vivo Activities Through Glycoengineering," Nature Biotechnol. 21:414-21; Shields, R. L. et al. (2002) "Lack of Fucose on Human IgG N-Linked Oligosaccharide Improves Binding to Human Fcgamma RIII And Antibody-Dependent Cellular Toxicity," J. Biol. Chem. 277(30): 26733-26740)]을 참조한다.
유도체 항체 또는 항체 단편은 항체 의존성 세포독성(ADCC), 항체 의존성 세포 식세포작용(ADCP), 항체 의존성 호중구 식세포작용(ADNP), 또는 항체 의존성 보체 침착(ADCD) 기능에서 바람직한 수준의 활성을 부여하기 위해 조작된 서열 또는 글리코실화 상태로 생성될 수 있으며, 이는 비드 기반 또는 세포 기반 분석 또는 동물 모델의 생체내 연구에 의해 측정되는 바와 같다.
유도체 항체 또는 항체 단편은 다음에 제한되는 것은 아니나, 특이적 화학적 절단, 아세틸화, 제형화, 투니카마이신의 대사 합성 등을 포함하는 당업자에게 공지된 기술을 사용하여 화학적 변형에 의해 변형될 수 있다. 일 실시양태에서, 항체 유도체는 모 항체와 유사하거나 동일한 기능을 가질 것이다. 또 다른 실시양태에서, 항체 유도체는 모 항체에 비해 변경된 활성을 나타낼 것이다. 예를 들어, 유도체 항체(또는 이의 단편)는 모 항체보다 이의 에피토프에 더 단단히 결합하거나 단백질 분해에 더 내성이 있을 수 있다.
C. 항체 서열의 조작
다양한 실시양태에서, 개선된 발현, 개선된 교차 반응성 또는 감소된 표적외 결합과 같은 다양한 이유로 선택하여 확인된 항체의 서열을 조작할 수 있다. 변형된 항체는 표준 분자 생물학적 기술을 통한 발현, 또는 폴리펩타이드의 화학적 합성을 포함하는 당업자에게 공지된 임의의 기술에 의해 제조될 수 있다. 재조합 발현 방법은 이 문서의 다른 곳에서 다룬다. 다음은 항체 조작에 대한 관련 목표 기술에 대한 일반적인 논의이다.
하이브리도마를 배양한 다음, 세포를 용해시키고, 총 RNA를 추출할 수 있다. 무작위 6량체를 RT에 사용하여 RNA의 cDNA 카피를 생성한 다음 모든 인간 가변 유전자 서열을 증폭할 것으로 예상되는 PCR 프라이머의 다중복합 혼합물을 사용하여 PCR을 수행할 수 있다. PCR 산물은 pGEM-T Easy 벡터에 클로닝된 다음 표준 벡터 프라이머를 사용하여 자동화된 DNA 시퀀싱에 의해 시퀀싱될 수 있다. 결합 및 중화의 분석을 하이브리도마 상청액으로부터 수집된 항체를 사용하여 수행하고 단백질 G 컬럼을 사용하여 FPLC로 정제할 수 있다.
재조합 전장 IgG 항체를 클로닝 벡터로부터의 중쇄 및 경쇄 Fv DNA를 IgG 플라스미드 벡터로 서브클로닝하여 생성할 수 있고, 293(예를 들어, Freestyle) 세포 또는 CHO 세포로 형질감염시키고, 293 또는 CHO 세포 상청액으로부터 항체를 수집하고 정제할 수 있다. 다른 적절한 숙주 세포계는 E. 콜라이(E. coli)와 같은 박테리아, 곤충 세포(S2, Sf9, Sf29, High Five), 식물 세포(예를 들어, 담배, 인간 유사 글리칸에 대한 조작의 존재 또는 부재), 조류 또는 마우스, 랫트, 염소 또는 소와 같은 다양한 비인간 트랜스제닉 대상체를 포함한다.
후속 항체 정제 및 숙주의 면역화 둘 모두를 위한 항체를 인코딩하는 핵산의 발현이 또한 고려된다. 항체 코딩 서열은 천연 RNA 또는 변형된 RNA와 같은 RNA일 수 있다. 변형된 RNA는 mRNA에 증가된 안정성과 낮은 면역원성을 부여하여 치료적으로 중요한 단백질의 발현을 촉진하는 특정 화학적 변형을 고려한다. 예를 들어, N1-메틸-슈도우리딘(N1mΨ)은 번역 작용 면에서 여러 다른 뉴클레오사이드 변형 및 이의 조합을 상회한다. 면역/eIF2α 인산화 의존성 번역 억제를 중단시키는 것 외에도 혼입된 N1mΨ 뉴클레오타이드는 리보솜 일시 중지 및 mRNA의 밀도를 증가시켜 번역 과정의 역학을 극적으로 변경한다. 변형된 mRNA의 증가된 리보솜 추가는 동일한 mRNA에서 리보솜 재활용 또는 새로운 리보솜 모집에 유리하여 개시를 더 용이하게 한다. 이러한 변형은 RNA 접종 후 생체내에서 항체 발현을 향상시키는데 사용될 수 있다. 천연 또는 변형된 RNA는 네이키드 RNA로서 또는 지질 나노입자와 같은 전달 비히클에서 전달될 수 있다.
대안적으로, 항체를 인코딩하는 DNA는 동일한 목적을 위해 사용될 수 있다. DNA는 그것이 설계된 숙주 세포에서 활성인 프로모터를 포함하는 발현 카세트에 포함된다. 발현 카세트는 유리하게는 통상적인 플라스미드 또는 미니벡터와 같은 복제가능한 벡터에 포함된다. 벡터는 폭스바이러스, 아데노바이러스, 헤르페스바이러스, 아데노-연관 바이러스와 같은 바이러스 벡터를 포함하고, 렌티바이러스가 고려된다. VEE 바이러스 또는 신드비스 바이러스에 기반한 알파바이러스 레플리콘과 같은 항체 유전자를 인코딩하는 레플리콘이 또한 고려된다. 이러한 벡터의 전달은 근육내, 피하 또는 피내 경로를 통한 바늘에 의해, 또는 생체내 발현이 요망되는 경우 경피적 전기천공에 의해 수행될 수 있다.
최종 cGMP 제조 과정과 동일한 숙주 세포 및 세포 배양 과정에서 생산된 항체의 신속한 가용성은 과정 개발 프로그램의 기간을 단축시킬 가능성이 있다. Lonza는 CHO 세포에서 소량(최대 50g)의 항체를 신속하게 생산하기 위해 CDACF 배지에서 성장한 풀링된 형질감염체를 사용하는 일반적인 방법을 개발했다. 진정한 일시적인 시스템보다 약간 더 느리긴 하지만 장점에는 더 높은 산물 농도와 생산 세포주와 동일한 숙주 및 과정의 사용이 포함된다. 일회용 생물반응기, 유가식(fed-batch mode)으로 작동되는 일회용 백 생물반응기 배양물(5L 작업 부피), 2g/L의 수확 항체 농도에서 모델 항체를 발현하는 GS-CHO 풀의 성장 및 생산성의 예는 형질감염 9주 이내에 달성되었다.
항체 분자는 예를 들어 mAb의 단백질 분해 절단에 의해 생산되는 단편(예를 들어, F(ab'), F(ab')2), 또는 예를 들어 재조합 수단에 의해 생산 가능한 단일 사슬 면역글로불린을 포함할 것이다. F(ab') 항체 유도체는 1가이고 F(ab')2 항체 유도체는 2가이다. 일 실시양태에서, 이러한 단편은 서로 조합되거나 다른 항체 단편 또는 수용체 리간드와 조합되어 "키메라" 결합 분자를 형성할 수 있다. 유의하게도, 이러한 키메라 분자는 동일한 분자의 상이한 에피토프에 결합할 수 있는 치환기를 포함할 수 있다.
관련 실시양태에서, 항체는 개시된 항체의 유도체, 예를 들어, 개시된 항체에서와 동일한 CDR 서열을 포함하는 항체 (예를 들어, 키메라 또는 CDR-이식된 항체)이다. 대안적으로, 항체 분자에 보존적 변화를 도입하는 것과 같은 변형을 고려할 수 있다. 이러한 변화를 수행할 때 아미노산의 수성 인덱스(hydropathic index)를 고려할 수 있다. 단백질에 상호작용적 생물학적 기능을 부여하는데 있어서 수성 아미노산 인덱스의 중요성은 일반적으로 당업계에서 이해된다(문헌[Kyte and Doolittle, 1982]). 아미노산의 상대적인 수성 특성은 결과 단백질의 2차 구조에 기여하며, 이는 결과적으로 단백질과 다른 분자, 예를 들어, 효소, 기질, 수용체, DNA, 항체, 항원, 등의 상호작용을 정의한다.
유사 아미노산의 치환은 친수성에 기반하여 효과적으로 이루어질 수 있음이 또한 당업계에서 이해된다. 본 명세서에 참조로 포함된 미국 특허 제 4,554,101호는 인접 아미노산의 친수성에 의해 지배되는 단백질의 최대 국소 평균 친수성이 단백질의 생물학적 특성과 상관관계가 있다고 기재하고 있다. 미국 특허 제 4,554,101호에 상세히 기재된 바와 같이, 다음 친수성 값이 아미노산 잔기에 할당되었다: 염기성 아미노산: 아르기닌(+3.0), 리신(+3.0) 및 히스티딘(-0.5); 산성 아미노산: 아스파르테이트(+3.0 ± 1), 글루타메이트(+3.0 ± 1), 아스파라긴(+0.2) 및 글루타민(+0.2); 친수성 비이온성 아미노산: 세린(+0.3), 아스파라긴(+0.2), 글루타민(+0.2) 및 트레오닌(-0.4), 황 포함 아미노산: 시스테인(-1.0) 및 메티오닌(-1.3); 소수성 비방향족 아미노산: 발린(-1.5), 류신(-1.8), 이소류신(-1.8), 프롤린(-0.5 ± 1), 알라닌(-0.5) 및 글리신(0); 소수성 방향족 아미노산: 트립토판(-3.4), 페닐알라닌(-2.5), 티로신(-2.3).
아미노산은 유사한 친수성을 갖는 다른 것에 의해 치환될 수 있고 생물학적 또는 면역학적으로 변형된 단백질을 생산할 수 있는 것으로 이해된다. 이러한 변화에 있어서, 친수성 값이 ±2 이내인 아미노산의 치환이 바람직하고, ±1 이내가 특히 바람직하고, ±0.5 이내가 더욱 특히 바람직하다.
위에서 개략적으로 기재된 바와 같이, 아미노산 치환은 일반적으로 아미노산 측쇄 치환기의 상대적 유사성, 예를 들어, 소수성, 친수성, 전하, 크기 등에 기반한다. 다양한 전술한 특성을 고려하는 예시적인 치환은 당업자에게 잘 알려져 있으며, 아르기닌 및 리신; 글루타메이트 및 아스파르테이트; 세린 및 트레오닌; 글루타민 및 아스파라긴; 및 발린, 류신 및 이소류신을 포함한다.
본 개시내용은 또한 이소형 변형을 고려한다. 상이한 이소형을 갖도록 Fc 영역을 변형함으로써 상이한 기능이 달성될 수 있다. 예를 들어, IgG1으로의 변화는 항체 의존성 세포 독성을 증가시킬 수 있고, 클래스 A로의 전환은 조직 분포를 개선할 수 있고, 클래스 M으로의 전환은 원자가를 향상시킬 수 있다.
대안적으로 또는 추가로, 아미노산 변형을 IL-23p19 결합 분자의 Fc 영역의 C1q 결합 및/또는 보체 의존성 세포독성(CDC) 기능을 변경하는 하나 이상의 추가 아미노산 변형과 조합하는 것이 유용할 수 있다. 특히 해당 결합 폴리펩타이드는 C1q에 결합하고 보체 의존성 세포독성을 나타내는 것일 수 있다. 선택적으로 CDC를 매개하는 능력을 추가로 갖는 기존의 C1q 결합 활성을 갖는 폴리펩타이드는 이들 활성 중 하나 또는 둘 모두가 향상되도록 변형될 수 있다. C1q를 변경하고/거나 이의 보체 의존성 세포독성 기능을 변이하는 아미노산 변형은 예를 들어 본 명세서에 참조로 포함된 WO/0042072에 기재되어 있다.
예를 들어, C1q 결합 및/또는 FcγR 결합을 변형시켜 CDC 활성 및/또는 ADCC 활성을 변화시킴으로써 변경된 효과기 기능을 갖는 항체의 Fc 영역을 설계할 수 있다. "효과기 기능"은 생물학적 활성(예를 들어, 대상체에서)을 활성화 또는 감소시키는 역할을 한다. 효과기 기능의 예는 다음에 제한되는 것은 아니나, C1q 결합; 보체 의존성 세포독성(CDC); Fc 수용체 결합; 항체 의존성 세포 매개 세포독성(ADCC); 식균 작용; 세포 표면 수용체(예를 들어, B 세포 수용체; BCR)의 하향 조절 등을 포함한다. 이러한 효과기 기능은 Fc 영역과 결합 도메인(예를 들어, 항체 가변 도메인)의 조합이 필요할 수 있으며 다양한 분석(예를 들어, Fc 결합 분석, ADCC 분석, CDC 분석 등)을 사용하여 평가될 수 있다.
예를 들어, 개선된 C1q 결합 및 개선된 FcγRIII 결합(예를 들어, 개선된 ADCC 활성 및 개선된 CDC 활성 둘 모두를 가짐)을 갖는 항체의 변이체 Fc 영역을 생성할 수 있다. 대안적으로, 효과기 기능이 감소되거나 제거되는 것이 바람직하다면, 변이체 Fc 영역은 감소된 CDC 활성 및/또는 감소된 ADCC 활성으로 조작될 수 있다. 다른 실시양태에서, 이들 활성 중 하나만이 증가될 수 있고, 선택적으로 다른 활성도 감소될 수 있다(예를 들어, 개선된 ADCC 활성을 갖지만 CDC 활성이 감소된 Fc 영역 변이체를 생성하기 위한 경우 및 그 반대의 경우도 마찬가지임).
FcRn 결합. Fc 돌연변이는 또한 신생아 Fc 수용체(FcRn)와의 상호작용을 변경하고 약동학적 특성을 개선하기 위해 도입 및 조작될 수 있다. FcRn에 대한 결합이 개선된 인간 Fc 변이체의 집합이 기재되었다(문헌[Shields et al., (2001)]). FcγRI, FcγRII, FcγRIII 및 FcRn에 대한 인간 IgG1의 결합 부위의 고분해능 매핑 및 FcγR에 대한 개선된 결합을 갖는 IgG1 변이체의 설계(문헌[J. Biol. Chem. 276:6591-6604]). 알라닌 스캐닝 돌연변이 유발, 무작위 돌연변이 유발 및 신생아 Fc 수용체(FcRn)에 대한 결합 및/또는 생체내 거동을 평가하기 위한 스크리닝을 포함한 기술을 통해 생성될 수 있는 아미노산 변형을 포함하여 반감기를 증가시킬 수 있는 많은 방법이 알려져 있다(문헌[Kuo and Aveson, (2011)]). 돌연변이 유발이 뒤따르는 컴퓨터 전략을 사용하여 돌연변이시킬 아미노산 돌연변이 중 하나를 선택할 수도 있다.
따라서, 본 개시내용은 FcRn에 대한 최적화된 결합을 갖는 항원 결합 단백질의 변이체를 제공한다. 특정 실시양태에서, 항원 결합 단백질의 상기 변이체는 상기 항원 결합 단백질의 Fc 영역에 적어도 하나의 아미노산 변형을 포함하고, 상기 변형은 상기 모 폴리펩타이드와 비교하여, Fc 영역의 226, 227, 228, 230, 231, 233, 234, 239, 241, 243, 246, 250, 252, 256, 259, 264, 265, 267, 269, 270, 276, 284, 285, 288, 289, 290, 291, 292, 294, 297, 298, 299, 301, 302, 303, 305, 307, 308, 309, 311, 315, 317, 320, 322, 325, 327, 330, 332, 334, 335, 338, 340, 342, 343, 345, 347, 350, 352, 354, 355, 356, 359, 360, 361, 362, 369, 370, 371, 375, 378, 380, 382, 384, 385, 386, 387, 389, 390, 392, 393, 394, 395, 396, 397, 398, 399, 400, 401 403, 404, 408, 411, 412, 414, 415, 416, 418, 419, 420, 421, 422, 424, 426, 428, 433, 434, 438, 439, 440, 443, 444, 445, 446 및 447로 이루어진 군으로부터 선택되며, Fc 영역의 아미노산 넘버링은 카밧의 EU 인덱스의 넘버링이다. 본 개시내용의 추가 양상에서 변형은 M252Y/S254T/T256E이다.
또한, 다양한 간행물은 반감기가 변형된 생리학적 활성 분자를 얻는 방법을 기재하고 있으며, 예를 들어 FcRn 결합 폴리펩타이드를 분자에 도입하거나 FcRn 결합 친화도는 보존되지만 다른 Fc 수용체에 대한 친화도는 크게 감소된 항체와 분자를 융합하거나 항체의 FcRn 결합 도메인과 융합시킨 문헌[Kontermann(2009)]을 참조한다.
유도체화된 항체는 포유류, 특히 인간에서 모 항체의 반감기(예를 들어, 혈청 반감기)를 변경하기 위해 사용될 수 있다. 이러한 변경은 15일 초과, 바람직하게는 20일 초과, 25일 초과, 30일 초과, 35일 초과, 40일 초과, 45일 초과, 2개월 초과, 3개월 초과, 4개월 초과 또는 5개월 초과의 반감기를 초래할 수 있다. 포유류, 바람직하게는 인간에서 본 개시내용의 항체 또는 이의 단편의 증가된 반감기는 포유류에서 상기 항체 또는 항체 단편의 더 높은 혈청 역가를 초래하고, 따라서 상기 항체 또는 항체 단편의 투여 빈도를 감소시키고/거나, 투여될 상기 항체 또는 항체 단편의 농도를 감소시킨다. 증가된 생체내 반감기를 갖는 항체 또는 이의 단편은 당업자에게 공지된 기술에 의해 생성될 수 있다. 예를 들어, 생체내 반감기가 증가된 항체 또는 이의 단편은 Fc 도메인과 FcRn 수용체 사이의 상호작용에 관여하는 것으로 확인된 아미노산 잔기를 변형(예를 들어, 치환, 결실 또는 추가)함으로써 생성될 수 있다.
문헌[Beltramello et al. (2010)]은 이전에 CH2 도메인의 위치 1.3과 1.2에 있는 류신 잔기(C-도메인에 대한 IMGT 고유 넘버링에 따름)를 알라닌 잔기에 의해 치환시켜 생성함으로써, 뎅기열 바이러스 감염을 향상시키는 경향으로 인해 중화 mAb의 변형을 보고하였다. "LALA" 돌연변이로도 알려진 이 변형은 문헌[Hessell et al. (2007)]에 의해 기재된 바와 같이, FcγRI, FcγRII 및 FcγRIIIa에 대한 항체 결합을 제거한다. 변이체 및 변형되지 않은 재조합 mAb는 4가지 뎅기열 바이러스 혈청형에 의한 감염을 중화하고 향상시키는 능력에 대해 비교되었다. LALA 변이체는 변형되지 않은 mAb와 동일한 중화 활성을 유지했지만 향상 활성은 전혀 없었다. 따라서 이러한 성질의 LALA 돌연변이는 현재 개시된 항체의 맥락에서 고려된다.
변경된 글리코실화. 본 개시내용의 특정 실시양태는 시알산, 갈락토스 또는 푸코스가 없는 실질적으로 균질한 글리칸을 포함하는 단리된 단일클론 항체 또는 이의 항원 결합 단편이다. 단일클론 항체는 중쇄 가변 영역 및 경쇄 가변 영역을 포함하며, 이들 둘 모두는 각각 중쇄 또는 경쇄 불변 영역에 부착될 수 있다. 전술한 실질적으로 균질한 글리칸은 중쇄 불변 영역에 공유적으로 부착될 수 있다.
본 개시내용의 또 다른 실시양태는 신규 Fc 글리코실화 패턴을 갖는 mAb를 포함한다. 단리된 단일클론 항체 또는 이의 항원 결합 단편은 GNGN 또는 G1/G2 당형태으로 표시되는 실질적으로 균질한 조성으로 존재한다. Fc 글리코실화는 치료 mAb의 항바이러스 및 항암 특성에서 중요한 역할을 한다. 본 개시내용은 시험관내에서 푸코스가 없는 항-HIV mAb의 항-렌티바이러스 세포-매개 바이러스 억제의 증가를 보여주는 최근 연구와 일치한다. 코어 푸코스가 부재하는 균질한 글리칸을 갖는 본 개시내용의 이 실시양태는 2배 초과에 의해 특정 바이러스에 대한 증가된 보호를 나타내었다. 코어 푸코스를 제거하면 천연 살해(NK) 세포에 의해 매개되는 mAb의 ADCC 활성이 극적으로 향상되지만 다형핵 세포(PMN)의 ADCC 활성에는 반대 효과가 있는 것으로 보인다.
GNGN 또는 G1/G2 당형태로 표시되는 실질적으로 균질한 조성을 포함하는 단리된 단일클론 항체 또는 이의 항원 결합 단편은 G0, G1F, G2F, GNF, GNGNF 또는 GNGNFX 포함 당형태의 존재 및 실질적으로 균질한 GNGN 당형태의 부재 하의 동일한 항체와 비교하여 Fc 감마 RI 및 Fc 감마 RIII에 대해 증가된 결합 친화도를 나타낸다. 본 개시내용의 일 실시양태에서, 항체는 1 x 10-8 M 이하의 Kd로 Fc 감마 RI로부터 해리되고 1 x 10-7 M 이하의 Kd로 Fc 감마 RIII로부터 해리된다.
Fc 영역의 글리코실화는 통상적으로 N-연결 또는 O-연결이다. N-연결은 탄수화물 모이어티가 아스파라긴 잔기의 측쇄에 부착되는 것을 지칭한다. O-연결된 글리코실화는 당 N-아세틸갈락토사민, 갈락토스 또는 자일로스 중 하나가 하이드록시아미노산, 가장 일반적으로 세린 또는 트레오닌에 부착되는 것을 지칭하지만, 5-하이드록시프롤린 또는 5-하이드록시리신도 사용할 수 있다. 아스파라긴 측쇄 펩타이드 서열에 대한 탄수화물 모이어티의 효소적 부착에 대한 인식 서열은 아스파라긴-X-세린 및 아스파라긴-X-트레오닌이며, X는 프롤린을 제외한 임의의 아미노산이다. 따라서, 폴리펩타이드에서 이들 펩타이드 서열 중 하나의 존재는 가능한 글리코실화 부위를 생성한다.
글리코실화 패턴은, 예를 들어 폴리펩타이드에 존재하는 하나 이상의 글리코실화 부위(들)를 결실시키고/거나 폴리펩타이드에 존재하지 않는 하나 이상의 글리코실화 부위(들)를 추가함으로써, 변경될 수 있다. 항체의 Fc 영역에 대한 글리코실화 부위의 추가는 아미노산 서열이 하나 이상의 상기 기재된 트리펩타이드 서열을 포함하도록 변경함으로써 편리하게 달성된다(N-연결 글리코실화 부위의 경우). 예시적인 글리코실화 변이체는 중쇄의 잔기 Asn 297의 아미노산 치환을 갖는다. 변경은 또한 원래의 폴리펩타이드의 서열에 하나 이상의 세린 또는 트레오닌 잔기를 추가하거나 치환함으로써 이루어질 수 있다(O-연결된 글리코실화 부위의 경우). 또한 Asn 297을 Ala로 변이하면 글리코실화 부위 중 하나가 제거될 수 있다.
특정 실시양태에서, 항체는 GnT III가 IL-23p19 항체에 GlcNAc를 추가하도록 베타 (1,4)-N-아세틸글루코사미닐트랜스퍼라제 III(GnT III)를 발현하는 세포에서 발현된다. 이러한 방식으로 항체를 생산하는 방법은 WO/9954342, WO/03011878, 특허 공개 20030003097A1 및 문헌[Umana et al., Nature Biotechnology, 17:176-180, February 1999]에 제공되어 있다. 세포주는 규칙적인 간격을 갖는 짧은 회문구조 반복단위 배열(Clustered Regularly Interspaced Short Palindromic Repeats) (CRISPR)와 같은 게놈 편집 기술을 사용하여 글리코실화와 같은 특정 번역 후 변형을 향상 또는 감소 또는 제거하기 위해 변경될 수 있다. 예를 들어, CRISPR 기술은 재조합 단일클론 항체를 발현하는데 사용되는 293 또는 CHO 세포에서 글리코실화 효소를 인코딩하는 유전자를 제거하는데 사용할 수 있다.
단일클론 항체 단백질 서열 관련성의 제거. 인간 B 세포에서 얻은 항체 가변 유전자 서열을 조작하여 제조 가능성과 안전성을 향상시키는 것이 가능하다. 다음을 포함하는 부위와 관련된 서열 모티프를 검색하여 가능한 단백질 서열 관련성을 확인할 수 있다:
1) 비쌍 Cys 잔기,
2) N-연결된 글리코실화,
3) Asn 탈아미드화,
4) Asp 이성질체화,
5) SYE 절단,
6) Met 산화,
7) Trp 산화,
8) N-말단 글루타메이트,
9) 인테그린 결합,
10) CD11c/CD18 결합, 또는
11) 단편화
이러한 모티프는 재조합 항체를 인코딩하는 cDNA에 대한 합성 유전자를 변경함으로써 제거될 수 있다.
치료용 항체 개발 분야의 단백질 조작 실험은 특정 서열 또는 잔기가 용해도 차이와 관련되어 있음을 분명히 드러낸다(문헌[Fernandez-Escamilla et al., Nature Biotech., 22 (10), 1302-1306, 2004; Chennamsetty et al., PNAS, 106 (29), 11937-11942, 2009; Voynov et al., Biocon. Chem., 21 (2), 385-392, 2010]). 문헌에서 용해도-변경 돌연변이의 증거는 일부 아스파라긴산, 글루탐산 및 세린과 같은 일부 친수성 잔기는 아스파라긴, 글루타민, 트레오닌, 리신 및 아르기닌과 같은 다른 친수성 잔기보다 단백질 용해도에 훨씬 더 유리하게 기여함을 나타낸다.
안정성. 항체는 향상된 생물물리학적 특성을 위해 조작될 수 있다. 평균 겉보기 용융 온도를 사용하여 상대적 안정성을 결정하기 위해 항체의 접힘을 풀기 위해 상승된 온도를 사용할 수 있다. 시차 주사 열량계(DSC)는 온도의 함수로 분자의 열용량(Cp)(도당 가온하는데 필요한 열)을 측정한다. DSC를 사용하여 항체의 열 안정성을 연구할 수 있다. mAb에 대한 DSC 데이터는 때때로 mAb 구조 내 개별 도메인의 접힘의 풀림을 처리하여 서모그램에서 최대 3개의 피크(Fab, CH2 및 CH3 도메인의 접힘의 풀림으로부터)를 생산하기 때문에 특히 흥미롭다. 일반적으로 Fab 도메인의 접힘의 풀림은 가장 강한 피크를 생산한다. Fc 부분의 DSC 프로파일 및 상대적 안정성은 인간 IgG1, IgG2, IgG3, 및 IgG4 하위클래스에 대한 특징적인 차이를 보여준다(문헌[Garber and Demarest, Biochem. Biophys. Res. Commun. 355, 751-757, 2007]). CD 분광기로 수행되는 원형 이색성(CD)을 사용하여 평균 겉보기 용융 온도를 결정할 수도 있다. Far-UV CD 스펙트럼은 0.5 nm 증분으로 200 내지 260 nm 범위의 항체에 대해 측정된다. 최종 스펙트럼은 20개 누적의 평균으로 결정할 수 있다. 잔여 타원도 값은 배경을 제외한 후에 계산할 수 있다. 항체(0.1 mg/mL)의 열 접힘의 풀림은 25 내지 95℃ 및 1℃/min의 가열 속도에서 235 nm에서 모니터링할 수 있다. 동적 광산란(DLS)을 사용하여 응집 성향을 평가할 수 있다. DLS는 단백질을 포함한 다양한 입자의 크기를 특성화하는데 사용된다. 시스템의 크기가 분산되지 않은 경우 입자의 평균 유효 직경을 결정할 수 있다. 이 측정은 입자 핵의 크기, 표면 구조의 크기 및 입자 농도에 따라 다르다. DLS는 필수적으로 입자로 인한 산란광 강도의 변동을 측정하므로 입자의 확산 계수를 결정할 수 있다. 상용 DLA 기기의 DLS 소프트웨어는 다양한 직경의 입자 집단을 표시한다. 안정성 연구는 DLS를 사용하여 편리하게 수행할 수 있다. 샘플의 DLS 측정은 입자의 유체역학적 반경이 증가하는지를 결정하여 시간이 지남에 따라 또는 온도 변화에 따라 입자가 응집되는지를 나타낼 수 있다. 입자가 응집하면 더 큰 반경을 가진 더 많은 입자 집단을 볼 수 있다. 온도에 따른 안정성은 현장 온도를 제어하여 분석할 수 있다. 모세관 전기영동(CE) 기술에는 항체 안정성의 특징을 결정하기 위한 입증된 방법론이 포함된다. iCE 접근법을 사용하여 탈아미드화, C-말단 리신, 시알화, 산화, 글리코실화 및 단백질의 pI 변화를 초래할 수 있는 단백질에 대한 기타 변화로 인한 항체 단백질 전하 변이체를 처리할 수 있다. 각각의 발현된 항체 단백질은 Protein Simple Maurice 기기를 사용하여 모세관 컬럼(cIEF)에서 높은 처리량, 유리 용액 등전점(IEF)으로 평가할 수 있다. 전체 열 UV 흡수 검출은 등전점(pIs)에 초점을 맞춘 분자의 실시간 모니터링을 위해 30초마다 수행할 수 있다. 이 접근법은 기존 겔 IEF의 고분해능과 컬럼 기반 분리에서 볼 수 있는 정량 및 자동화의 장점을 조합하고 모집 단계의 필요성을 제거한다. 이 기술은 발현된 항체에 대한 동일성, 순도 및 이질성 프로파일의 재현 가능한 정량 분석을 산출한다. 결과는 흡광도 및 기본 형광 검출 모드와 0.7 μg/mL까지의 검출 감도를 사용하여 항체의 전하 이질성과 분자 크기를 확인한다.
용해도. 항체 서열의 고유 용해도 점수를 결정할 수 있다. 고유 용해도 점수는 CamSol Intrinsic을 사용하여 계산할 수 있다(문헌[Sormanni et al., J Mol Biol 427, 478-490, 2015]). scFv와 같은 각 항체 단편의 HCDR3에서 잔기 95 내지 102(카밧 넘버링)에 대한 아미노산 서열은 용해도 점수를 계산하기 위해 온라인 프로그램을 통해 평가될 수 있다. 실험실 기술을 사용하여 용해도를 결정할 수도 있다. 용액이 포화되고 용해도 한계에 도달할 때까지 동결건조된 단백질을 용액에 첨가하거나 적합한 분자량 컷오프를 갖는 미세농축기에서 한외여과에 의한 농축을 포함한 다양한 기술이 존재한다. 가장 간단한 방법은 황산 암모늄을 사용하여 단백질 침전을 포함하는 방법을 사용하여 단백질 용해도를 측정하는 비정질 침전을 유도하는 것이다(문헌[Trevino et al., J Mol Biol, 366: 449-460, 2007]). 황산 암모늄 침전은 상대 용해도 값에 대한 빠르고 정확한 정보를 제공한다. 황산 암모늄 침전은 수성 및 고체상이 잘 정의된 침전 용액을 생산하고 상대적으로 적은 양의 단백질이 필요하다. 황산 암모늄에 의한 비정질 침전의 유도를 사용하여 수행된 용해도 측정은 다른 pH 값에서도 쉽게 수행할 수 있다. 단백질 용해도는 pH 의존성이 크며 pH는 용해도에 영향을 미치는 가장 중요한 외적 요인으로 고려된다.
자가반응성. 일반적으로 자가반응 클론은 음성선택에 의해 개체발생 동안 제거되어야 한다고 생각되지만 자가반응 특성을 가진 많은 인간 천연 발생 항체가 성숙한 성숙한 레퍼토리에 지속되고 자가반응이 병원체에 대한 많은 항체의 항바이러스 기능을 향상시킬 수 있다는 것이 분명해졌다. 초기 B 세포 발달 동안 항체의 HCDR3 루프는 종종 양전하가 다량 존재하고 자가반응 패턴을 나타내는 것으로 알려져 있다(문헌[Wardemann et al., Science 301, 1374-1377, 2003]). 현미경(부착형 HeLa 또는 HEp-2 상피 세포 사용) 및 유세포 분석 세포 표면 염색(현탁 Jurkat T 세포 및 293S 인간 배아 신장 세포 사용)에서 인간 유래 세포에 대한 결합 수준을 평가하여 소정의 항체의 자가반응을 테스트할 수 있다. 자가반응은 또한 조직 어레이의 조직에 대한 결합 평가를 사용하여 조사할 수 있다.
바람직한 잔기("인간 유사성"). 혈액 공여체의 인간 B 세포에 대한 B 세포 레퍼토리 심층 시퀀싱은 많은 최근 연구에서 광범위한 규모로 수행되고 있다. 인간 항체 레퍼토리의 상당 부분에 대한 서열 정보는 건강한 인간에게 공통적인 항체 서열 특징의 통계적 평가를 용이하게 한다. 인간 재조합 항체 가변 유전자 참조 데이터베이스의 항체 서열 특징에 대한 정보를 사용하여 항체 서열의 "인간 유사성"(HL)의 위치 특이적 정도를 추정할 수 있다. HL은 치료용 항체 또는 백신으로서의 항체와 같은 임상 용도의 항체 개발에 유용한 것으로 나타났다. 목표는 항체 약물의 효능을 현저히 감소시키거나 심각한 건강 영향을 유발할 수 있는 가능한 부작용 및 항항체 면역 반응을 감소시키기 위해 항체의 인간 유사성을 증가시키는 것이다. 총 약 4억 개 서열의 건강한 인간 혈액 공여체 3명의 조합된 항체 레퍼토리의 항체 특성을 평가하고 항체의 초가변 영역에 초점을 맞춘 새로운 "상대 인간 유사성"(rHL) 점수를 생성할 수 있다. rHL 점수를 통해 인간(양성 점수)과 비인간 서열(음성 점수)을 쉽게 구별할 수 있다. 항체는 인간 레퍼토리에서 일반적이지 않은 잔기가 제거되도록 조작될 수 있다.
D. 단일 사슬 항체
단일쇄 가변 단편(scFv)은 짧은(보통 세린, 글리신) 링커와 함께 연결된 면역글로불린의 중쇄 및 경쇄 가변 영역의 융합체이다. 이 키메라 분자는 불변 영역의 제거와 링커 펩타이드의 도입에도 불구하고 원래 면역글로불린의 특이성을 유지한다. 이 변형은 일반적으로 특이성을 변경하지 않은 채로 유지한다. 이러한 분자는 그동안 항원 결합 도메인을 단일 펩타이드로 발현하는 것이 매우 편리한 파지 디스플레이를 용이하게 하기 위해 생성되었다. 대안적으로, scFv는 하이브리도마 또는 B 세포로부터 유래된 서브클로닝된 중쇄 및 경쇄로부터 직접 생성될 수 있다. 단일 사슬 가변 단편에는 완전한 항체 분자에 존재하는 불변 Fc 영역이 없으므로 항체를 정제하는데 사용되는 공통 결합 부위(예를 들어, 단백질 A/G)가 없다. 이러한 단편은 단백질 L이 카파 경쇄의 가변 영역과 상호작용하기 때문에 종종 단백질 L을 사용하여 정제/고정될 수 있다.
가요성 링커는 일반적으로 알라닌, 세린 및 글리신과 같은 나선 및 회전 촉진 아미노산 잔기로 구성된다. 그러나 다른 잔기도 기능할 수 있다. 문헌[Tanget al. (1996)]은 단백질 링커 라이브러리에서 단일 사슬 항체(scFv)에 대한 맞춤형 링커를 신속하게 선택하는 수단으로 파지 디스플레이를 사용했다. 중쇄 및 경쇄 가변 도메인에 대한 유전자가 가변 조성의 18개 아미노산 폴리펩타이드를 인코딩하는 절편에 의해 연결된 무작위 링커 라이브러리를 작제하였다. scFv 레퍼토리(약 5 x 106개의 서로 다른 구성원)는 필라멘트 파지에 디스플레이되고 합텐과의 친화도 선택에 적용되었다. 선택된 변이체의 집단은 결합 활성에서 상당한 증가를 나타내었지만 상당한 서열 다양성을 유지하였다. 1054개의 개별 변이체를 스크리닝하여 후속적으로 가용성 형태로 효율적으로 생산된 촉매 활성 scFv를 산출했다. 서열 분석은 VH C 말단 후의 2개 링커 잔기에서 보존된 프롤린과 선택된 테더(tether)의 유일한 공통 특징으로서 다른 위치에서 아르기닌 및 프롤린의 존재량을 나타냈다.
본 개시내용의 재조합 항체는 또한 수용체의 이량체화 또는 다량체화를 가능하게 하는 서열 또는 모이어티를 포함할 수 있다. 이러한 서열은 J-사슬과 함께 다량체의 형성을 가능하게 하는 IgA로부터 유래된 서열을 포함한다. 다른 다량체화 도메인은 Gal4 이량체화 도메인이다. 다른 실시양태에서, 사슬은 2개의 항체의 조합을 가능하게 하는 비오틴/아비딘과 같은 제제로 변형될 수 있다.
별도의 실시양태에서, 단일-사슬 항체는 비-펩타이드 링커 또는 화학 단위를 사용하여 수용체 경쇄 및 중쇄를 연결함으로써 생성될 수 있다. 일반적으로, 경쇄 및 중쇄는 별개의 세포에서 생산되고, 정제되고, 후속적으로 적절한 방식으로 함께 연결될 것이다(즉, 중쇄의 N-말단이 적절한 화학적 가교를 통해 경쇄의 C-말단에 부착됨).
교차연결 시약은 2개의 상이한 분자, 예를 들어 안정화제 및 응고제의 작용기를 연결하는 분자 가교를 형성하는데 사용된다. 그러나, 동일한 유사체의 이량체 또는 다량체 또는 상이한 유사체로 구성된 헤테로머 복합체가 생성될 수 있는 것으로 고려된다. 2개의 상이한 화합물을 단계적으로 연결하기 위해, 부적절한 동종중합체 형성을 제거하는 이종이중기능성 교차 링커가 사용될 수 있다.
예시적인 이종 이중기능성 교차 링커는 2개의 반응기를 포함한다: 하나는 1차 아민 기(예를 들어, N-하이드록시 숙신이미드)와 반응하고 다른 하나는 티올 기(예를 들어, 피리딜 이황화물, 말레이미드, 할로겐 등)와 반응한다. 1차 아민 반응기를 통해 교차 링커는 하나의 단백질(예를 들어, 선택된 항체 또는 단편)의 리신 잔기(들)와 반응할 수 있고 티올 반응기를 통해 이미 제1 단백질에 연결된 교차 링커는 다른 단백질(예를 들어, 선택제)의 시스테인 잔기(유리 술프히드릴기)와 반응한다.
혈액 내에서 적당한 안정성을 갖는 교차 링커가 사용되는 것이 바람직하다. 표적화제 및 치료제/예방제를 접합하는데 성공적으로 사용될 수 있는 수많은 유형의 이황화 결합 포함 링커가 공지되어 있다. 입체 장애가 있는 이황화 결합을 포함하는 링커는 생체내에서 더 큰 안정성을 제공하여 작용 부위에 도달하기 전에 표적화 펩타이드의 방출을 방지할 수 있다. 따라서 이러한 링커는 연결제의 한 그룹이다.
또 다른 교차 연결 시약은 SMPT이며, 이는 인접한 벤젠 고리 및 메틸기에 의해 "입체 장애" 이황화 결합을 포함하는 이중기능성 교차 링커이다. 이황화 결합의 입체 장애는 조직 및 혈액에 존재할 수 있는 글루타티온과 같은 티올레이트 음이온에 의한 공격으로부터 결합을 보호하는 기능을 하여 표적 부위에 부착된 제제의 전달 전에 접합체의 분리를 방지하는데 도움이 되는 것으로 여겨진다.
많은 다른 공지된 교차 연결 시약과 마찬가지로 SMPT 교차 연결 시약은 시스테인의 SH 또는 1차 아민(예를 들어, 리신의 엡실론 아미노기)과 같은 작용기를 교차 연결하는 능력을 부여한다. 다른 가능한 유형의 교차 링커는 술포숙신이미딜-2-(p-아지도 살리실아미도) 에틸-1,3'-디티오프로피오네이트와 같은 절단 가능한 이황화 결합을 포함하는 이종 이중기능성 광반응성 페닐아지드를 포함한다. N-하이드록시-숙신이미딜 기는 1차 아미노 기와 반응하고 페닐아지드(광분해 시)는 임의의 아미노산 잔기와 비선택적으로 반응한다.
장애 교차 링커에 추가하여, 비 장애 링커도 본 명세서에 따라 사용될 수 있다. 보호된 이황화물을 포함하거나 생성하는 것으로 고려되지 않는 다른 유용한 교차 링커는 SATA, SPDP 및 2-이미노티올란을 포함한다(문헌[Wawrzynczak & Thorpe, 1987]). 이러한 교차 링커의 사용은 당업계에 잘 이해되어 있다. 다른 실시양태는 가요성 링커의 사용을 포함한다.
미국 특허 제 4,680,338호는 아민-포함 중합체 및/또는 단백질과 리간드의 접합체, 특히 킬레이트제, 약물, 효소, 검출 가능한 표지 등과 항체 접합체를 생산하는데 유용한 이중기능성 링커를 기재한다. 미국 특허 제 5,141,648호 및 제 5,563,250호는 다양한 온건한 조건하에서 절단가능한 불안정한 결합을 포함하는 절단가능한 접합체를 개시하고 있다. 이 링커는 해당 제제가 링커에 직접 결합될 수 있고 절단되어 활성제가 방출될 수 있다는 점에서 특히 유용하다. 특정 용도에는 항체 또는 약물과 같은 단백질에 유리 아미노 또는 유리 술프히드릴기를 추가하는 단계가 포함된다.
미국 특허 제 5,856,456호는 융합 단백질, 예를 들어, 단일 사슬 항체를 제조하기 위해 폴리펩타이드 구성성분을 연결하는데 사용하기 위한 펩타이드 링커를 제공한다. 링커는 길이가 최대 약 50개 아미노산이고, 하전된 아미노산(바람직하게는 아르기닌 또는 리신) 이후 프롤린을 적어도 1회 포함하고, 안정성이 더 높고 응집이 감소하는 것이 특징이다. 미국 특허 제 5,880,270호는 다양한 면역진단 및 분리 기술에 유용한 아미노옥시-포함 링커를 개시하고 있다.
E. 다중특이적 항체
특정 실시양태에서, 본 개시내용의 항체는 이중특이적 또는 다중특이적이다. 이중특이적 항체는 적어도 2개의 상이한 에피토프에 대한 결합 특이성을 갖는 항체이다. 예시적인 이중특이적 항체는 단일 항원의 2개의 상이한 에피토프에 결합할 수 있다. 다른 이러한 항체는 제1 항원 결합 부위를 제2 항원에 대한 결합 부위와 조합할 수 있다. 대안적으로, 항병원체 아암은 T 세포 수용체 분자(예를 들어, CD3) 또는 IgG의 Fc 수용체(FcγR), 예컨대 FcγRI (CD64), FcγRII (CD32) 및 Fc 감마 RIII (CD16)와 같은 백혈구의 유발 분자에 결합하는 아암과 조합되어, 감염된 세포에 세포 방어 기전을 집중시키고 국소화할 수 있다. 이중특이적 항체는 또한 감염된 세포에 세포독성제를 국소화하는데 사용될 수 있다. 이 항체는 병원체 결합 아암과 세포독성제(예를 들어, 사포린, 항-인터페론-α, 빈카 알칼로이드, 리신 A 사슬, 메토트렉세이트 또는 방사성 동위원소 합텐)에 결합하는 아암을 가지고 있다. 이중특이적 항체는 전장 항체 또는 항체 단편(예를 들어, F(ab')2 이중특이적 항체)으로 제조할 수 있다. WO 96/16673은 이중특이적 항-ErbB2/항-Fc 감마 RIII 항체를 기재하고, 미국 특허 제 5,837,234호는 이중특이적 항-ErbB2/항-Fc 감마 RI 항체를 개시하고 있다. 이중특이적 항-ErbB2/Fc 알파 항체는 WO98/02463에 제시되어 있다. 미국 특허 제 5,821,337호는 이중특이적 항-ErbB2/항-CD3 항체를 교시하고 있다.
이중특이적 항체의 제조 방법은 당업계에 공지되어 있다. 전장 이중특이적 항체의 통상적인 생산은 2개의 면역글로불린 중쇄-경쇄 쌍의 동시발현을 기반으로 하며, 2개의 사슬은 상이한 특이성을 갖는다(문헌[Millstein et al., Nature, 305:537-539 (1983)]). 면역글로불린 중쇄 및 경쇄의 무작위 분류로 인해, 이러한 하이브리도마(쿼드로마(quadroma))는 10개의 서로 다른 항체 분자의 가능한 혼합물을 생산하며, 그 중 하나만 정확한 이중특이적 구조를 갖는다. 일반적으로 친화도 크로마토그래피 단계에 의해 수행되는 정확한 분자의 정제는 다소 번거롭고 산물 수율이 낮다. 유사한 절차가 WO 93/08829 및 문헌[Traunecker et al., EMBO J., 10:3655-3659(1991)]에 개시되어 있다.
다른 접근법에 따르면, 적절한 결합 특이성을 갖는 항체 가변 영역(항체-항원 결합 부위)이 면역글로불린 불변 도메인 서열에 융합된다. 바람직하게는, 융합은 힌지, CH2 및 CH3 영역의 적어도 일부를 포함하는 Ig 중쇄 불변 도메인과의 융합이다. 적어도 하나의 융합체에 존재하는, 경쇄 결합에 필요한 부위를 포함하는 제1 중쇄 불변 영역(CH1)을 갖는 것이 바람직하다. 면역글로불린 중쇄 융합체 및 적절한 경우 면역글로불린 경쇄를 인코딩하는 DNA를 별도의 발현 벡터에 삽입하고 적합한 숙주 세포에 공동 형질감염시킨다. 이는 작제에 사용된 3개의 폴리펩타이드 사슬의 비균등한 비율이 적절한 이중특이적 항체의 최적 수율을 제공하는 경우의 실시양태에서 3개의 폴리펩타이드 단편의 상호 비율을 조정하는데 더 큰 가변성을 제공한다. 그러나 동일한 비율의 적어도 2개의 폴리펩타이드 사슬의 발현이 높은 수율을 초래하거나 비율이 적절한 사슬 조합의 수율에 유의한 영향을 미치지 않을 때 2개 또는 3개의 모든 폴리펩타이드 사슬에 대한 코딩 서열을 단일 발현 벡터에 삽입하는 것이 가능하다.
이 접근법의 특정 실시양태에서, 이중특이적 항체는 하나의 아암의 1차 결합 특이성을 갖는 혼성체 면역글로불린 중쇄, 및 다른 아암의 혼성체 면역글로불린 중쇄-경쇄 쌍(2차 결합 특이성 제공)으로 구성된다. 이중특이적 분자의 절반에만의 면역글로불린 경쇄의 존재가 용이한 분리 방법을 제공하기 때문에 이러한 비대칭 구조가 부적절한 면역글로불린 사슬 조합으로부터 적절한 이중특이적 화합물의 분리를 용이하게 하는 것으로 밝혀졌다. 이 접근법은 WO 94/04690에 개시되어 있다. 이중특이적 항체 생성에 대한 추가 세부사항은 예를 들어 문헌[Suresh et al., Methods in Enzymology, 121:210 (1986)]을 참조한다.
미국 특허 제 5,731,168호에 기재된 또 다른 접근법에 따르면, 한 쌍의 항체 분자 사이의 계면은 재조합 세포 배양물로부터 회수되는 이종이량체의 백분율이 최대화되도록 조작될 수 있다. 바람직한 계면은 CH3 도메인의 적어도 일부를 포함한다. 이 방법에서, 1차 항체 분자의 계면에서 하나 이상의 작은 아미노산 측쇄가 더 큰 측쇄(예를 들어, 티로신 또는 트립토판)로 대체된다. 큰 측쇄(들)와 동일하거나 유사한 크기의 보충적 "공동"은 큰 아미노산 측쇄를 더 작은 측쇄(예를 들어, 알라닌 또는 트레오닌)로 대체함으로써 2차 항체 분자의 계면에 생성된다. 이는 동종이량체와 같은 다른 부적절한 최종 산물보다 이종이량체의 수율을 증가시키는 기전을 제공한다.
이중특이적 항체는 교차 연결 또는 "이종접합체" 항체를 포함한다. 예를 들어, 이종접합체의 항체 중 하나는 아비딘에, 다른 하나는 비오틴에 결합될 수 있다. 이러한 항체는 예를 들어 면역계 세포를 부적절한 세포에 표적화하기 위해(미국 특허 제 4,676,980호), HIV 감염 치료를 위해(WO 91/00360, WO 92/200373 및 EP 03089) 제안되었다. 이종접합체 항체는 임의의 편리한 교차 연결 방법을 사용하여 제조될 수 있다. 적합한 교차 연결제는 당업계에 잘 알려져 있으며, 다수의 교차 연결 기술과 함께 미국 특허 제 4,676,980호에 개시되어 있다.
항체 단편으로부터 이중특이적 항체를 생성하는 기술은 또한 문헌에 기재되어 있다. 예를 들어, 이중특이적 항체는 화학적 연결을 사용하여 제조할 수 있다. 문헌[Brennan et al., Science, 229: 81 (1985)]은 온전한 항체가 단백질 분해로 절단되어 F(ab')2 단편을 생성하는 절차를 기재한다. 이 단편은 디티올 착화제인 아비산나트륨의 존재하에 환원되어 인접 디티올을 안정화하고 분자간 이황화물 형성을 방지한다. 생성된 Fab' 단편은 티오니트로벤조에이트(TNB) 유도체로 전환된다. 그런 다음 Fab'-TNB 유도체 중 하나는 메르캅토에틸아민에 의한 환원에 의해 Fab'-티올로 재전환되고 동몰량의 다른 Fab'-TNB 유도체와 혼합되어 이중특이적 항체를 형성한다. 생산된 이중특이적 항체는 효소의 선택적 고정화를 위한 제제로 사용될 수 있다.
이중특이적 항체를 형성하기 위해 화학적으로 연결될 수 있는 E. 콜라이로부터 Fab'-SH 단편의 직접 회수를 용이하게 하는 기술이 존재한다. 문헌[Shalaby et al., J. Exp. Med., 175: 217-225(1992)]에는 인간화 이중특이적 항체 F(ab')2 분자의 생산이 기재되어 있다. 각각의 Fab' 단편을 E. coli로부터 별도로 분비시키고 시험관내에서 지시된 화학적 연결을 적용하여 이중특이적 항체를 형성하였다. 이렇게 형성된 이중특이적 항체는 ErbB2 수용체를 과발현하는 세포 및 정상 인간 T 세포에 결합할 수 있을 뿐만 아니라 인간 유방 종양 표적에 대한 인간 세포독성 림프구의 용해 활성을 유발할 수 있다.
재조합 세포 배양물로부터 직접 이중특이적 항체 단편을 제조하고 단리하기 위한 다양한 기술이 또한 기재되어 있다(문헌[Merchant et al., Nat. Biotechnol. 16, 677-681 (1998). doi:10.1038/nbt0798-677pmid:9661204]). 예를 들어, 이중특이적 항체는 류신 지퍼를 사용하여 생산되었다(문헌[Kostelny et al., J. Immunol., 148(5):1547-1553, 1992]). Fos 및 Jun 단백질로부터의 류신 지퍼 펩타이드는 유전자 융합에 의해 2개의 상이한 항체의 Fab' 부분에 연결되었다. 항체 동종이량체는 힌지 영역에서 환원되어 단량체를 형성한 다음 재산화되어 항체 이종이량체를 형성하였다. 이 방법은 또한 항체 동종이량체의 생산에 활용될 수 있다. 문헌[Hollinger et al., Proc. Natl. Acad. Sci. USA, 90:6444-6448 (1993)]에 기재된 "디아바디" 기술은 이중특이적 항체 단편을 제조하기 위한 대안적인 기전을 제공하였다. 단편은 링커에 의해 VL에 연결된 VH를 포함하는데, 이 링커는 너무 짧아서 동일한 사슬의 두 도메인 사이의 쌍형성이 가능하지 않다. 따라서, 한 단편의 VH 및 VL 도메인은 다른 단편의 상보적 VL 및 VH 도메인과 쌍을 형성하도록 강제되어 2개의 항원 결합 부위를 형성한다. 단일 사슬 Fv(sFv) 이량체를 사용하여 이중특이적 항체 단편을 제조하는 또 다른 전략도 보고되었다. 문헌[Gruber et al., J. Immunol., 152:5368(1994)]을 참조한다.
특정 실시양태에서, 이중특이적 또는 다중특이적 항체는 DOCK-AND-LOCK™(DNL™) 복합체로서 형성될 수 있다(예를 들어, 미국 특허 제 7,521,056; 제 7,527,787호; 제 7,534,866호; 제 7,550,143호 및 제 7,666,400호 참조, 상기 문헌 각각의 실시예 섹션은 본 명세서에 참조로 포함됨). 일반적으로, 이 기술은 cAMP-의존성 단백질 키나제 (PKA)의 조절(R) 하위단위의 이량체화 및 도킹 도메인(DDD) 서열 및 다양한 AKAP 단백질 중 임의의 것으로부터 유래된 앵커 도메인(AD) 서열 사이에서 발생하는 특이적 고친화도 결합 상호작용을 이용한다(문헌[Baillie et al., FEBS Letters. 2005; 579: 3264; Wong and Scott, Nat. Rev. Mol. Cell Biol. 2004; 5:959]). DDD 및 AD 펩타이드는 임의의 단백질, 펩타이드 또는 기타 분자에 부착될 수 있다. DDD 서열이 자발적으로 이량체화되고 AD 서열에 결합하기 때문에, 이 기술에 의해 DDD 또는 AD 서열에 부착될 수 있는 임의의 선택된 분자 사이에 복합체를 형성할 수 있다.
2가 초과의 항체가 고려된다. 예를 들어, 삼중특이적 항체가 제조될 수 있다(문헌[Tutt et al., J. Immunol. 147: 60, 1991; Xu et al., Science, 358(6359):85-90, 2017]). 다가 항체는 항체가 결합하는 항원을 발현하는 세포에 의해 2가 항체보다 더 빨리 내재화(및/또는 이화)될 수 있다. 본 개시내용의 항체는 3개 이상의 항원 결합 부위를 갖는 다가 항체(예를 들어, 4가 항체)일 수 있으며, 이는 항체의 폴리펩타이드 사슬을 인코딩하는 핵산의 재조합 발현에 의해 용이하게 생산될 수 있다. 다가 항체는 이량체화 도메인 및 3개 이상의 항원 결합 부위를 포함할 수 있다. 바람직한 이량체화 도메인은 Fc 영역 또는 힌지 영역을 포함한다(또는 이로 이루어짐). 이 시나리오에서, 항체는 Fc 영역 및 Fc 영역에 대한 아미노 말단의 3개 이상의 항원 결합 부위를 포함할 것이다. 본 명세서에서 바람직한 다가 항체는 3개 내지 약 8개, 그러나 바람직하게는 4개의 항원 결합 부위를 포함한다(또는 이로 이루어짐). 다가 항체는 적어도 하나의 폴리펩타이드 사슬(및 바람직하게는 2개의 폴리펩타이드 사슬)을 포함하고, 폴리펩타이드 사슬(들)은 2개 이상의 가변 영역을 포함한다. 예를 들어, 폴리펩타이드 사슬(들)은 VD1-(X1)n-VD2-(X2)n-Fc를 포함할 수 있으며, VD1은 제1 가변 영역이고, VD2는 제2 가변 영역이고, Fc는 Fc 영역의 하나의 폴리펩타이드 사슬이고, X1 및 X2는 아미노산 또는 폴리펩타이드를 나타내고, n은 0 또는 1이다. 예를 들어, 폴리펩타이드 사슬(들)은 VH-CH1-가요성 링커-VH-CH1-Fc 영역 사슬; 또는 VH-CH1-VH-CH1-Fc 영역 사슬을 포함할 수 있다. 본 명세서의 다가 항체는 바람직하게는 적어도 2개(바람직하게는 4개)의 경쇄 가변 영역 폴리펩타이드를 추가로 포함한다. 본 명세서의 다가 항체는 예를 들어 약 2 내지 약 8개의 경쇄 가변 영역 폴리펩타이드를 포함할 수 있다. 본 명세서에서 고려되는 경쇄 가변 영역 폴리펩타이드는 경쇄 가변 영역을 포함하고, 선택적으로 CL 도메인을 추가로 포함한다.
전하 변형은 Fab 분자의 아미노산 치환으로 인해 경쇄와 일치하지 않는 중쇄의 쌍 형성 오류(Bence-Jones-유형 부산물)를 감소시킬 수 있는 다중특이적 항체의 맥락에서 특히 유용하고, 이는 결합 아암 중 하나(또는 2개 초과의 항원 결합 Fab 분자를 포함하는 분자의 경우)에서 VH/VL 교환을 갖는 Fab 기반 이중/다중특이적 항원 결합 분자의 생산에서 발생할 수 있다(또한 PCT 공개 WO 2015/150447, 특히 그 안의 실시예 참조, 상기 문헌은 그 전문이 본 명세서에 참조로 포함됨).
따라서, 특정 실시양태에서, 치료제에 포함된 항체는
(a) 제1 항원에 특이적으로 결합하는 제1 Fab 분자
(b) 제2 항원에 특이적으로 결합하고, Fab 경쇄 및 Fab 중쇄의 가변 도메인 VL 및 VH가 서로 대체되는 제2 Fab 분자
를 포함하고,
제1 항원은 활성화 T 세포 항원이고 제2 항원은 표적 세포 항원이거나, 제1 항원은 표적 세포 항원이고 제2 항원은 활성화 T 세포 항원이고;
i) a)의 제1 Fab 분자의 불변 도메인 CL에서 위치 124의 아미노산은 양으로 하전된 아미노산에 의해 치환되고(카밧에 따른 넘버링), a)의 제1 Fab 분자의 불변 도메인 CH1에서 위치 147의 아미노산 또는 위치 213의 아미노산은 음으로 하전된 아미노산에 의해 치환되거나(카밧 EU 인덱스에 따른 넘버링); 또는
ii) b)의 제2 Fab 분자의 불변 도메인 CL에서 위치 124의 아미노산은 양으로 하전된 아미노산에 의해 치환되고(카밧에 따른 넘버링), b)의 제2 Fab 분자의 불변 도메인 CH1에서 위치 147의 아미노산 또는 위치 213의 아미노산이 음으로 하전된 아미노산에 의해 치환된다(카캇 EU 인덱스에 따른 넘버링).
항체는 i) 및 ii)에 언급된 변형을 모두 포함하지 않을 수 있다. 제2 Fab 분자의 불변 도메인 CL 및 CH1은 서로 대체되지 않는다(즉, 교환되지 않은 상태로 유지됨).
항체의 또 다른 실시양태에서, a)의 제1 Fab 분자의 불변 도메인 CL에서 위치 124의 아미노산은 독립적으로 리신(K), 아르기닌(R) 또는 히스티딘(H)에 의해 치환되고(카밧 넘버링에 따름)(바람직한 일 실시양태에서, 독립적으로 리신(K), 또는 아르기닌(R)에 의함); a)의 제1 Fab 분자의 불변 도메인 CH1에서 위치 147의 아미노산 또는 위치 213의 아미노산은 독립적으로 글루탐산(E) 또는 아스파르트산(D)에 의해 치환된다(카밧 EU 인덱스에 따른 넘버링).
추가 실시양태에서, a)의 제1 Fab 분자의 불변 도메인 CL에서 위치 124의 아미노산은 독립적으로 리신(K), 아르기닌(R) 또는 히스티딘(H)에 의해 치환되고(카밧에 따른 넘버링), a)의 제1 Fab 분자의 불변 도메인 CH1에서 위치 147의 아미노산은 독립적으로 글루탐산(E) 또는 아스파르트산(D)에 의해 치환된다(카밧 EU 인덱스에 따른 넘버링).
특정 실시양태에서, a)의 제1 Fab 분자의 불변 도메인 CL에서 위치 124의 아미노산은 독립적으로 리신(K), 아르기닌(R) 또는 히스티딘(H)에 의해 치환되고(카밧에 따른 넘버링) (바람직한 일 실시양태에서 독립적으로 리신(K) 또는 아르기닌(R)에 의해 치환됨), 위치 123의 아미노산은 독립적으로 리신(K), 아르기닌(R) 또는 히스티딘(H)에 의해 치환되고(카밧에 따른 넘버링)(바람직한 일 실시양태에서 독립적으로 리신(K) 또는 아르기닌(R)에 의해 치환됨), a)의 제1 Fab 분자의 불변 도메인 CH1에서 위치 147의 아미노산은 독립적으로 글루탐산(E) 또는 아스파르트산(D)에 의해 치환되고 (카밧 EU 인덱스에 따른 넘버링), 위치 213의 아미노산이 독립적으로 글루탐산(E) 또는 아스파르트산(D)에 의해 치환된다(카밧 EU 인덱스에 따른 넘버링).
보다 특정한 실시양태에서, a)의 제1 Fab 분자의 불변 도메인 CL에서 위치 124에서의 아미노산은 리신(K)에 의해 치환되고(카밧에 따른 넘버링), 위치 123의 아미노산은 치환된 리신(K) 또는 아르기닌(R)에 의해 치환되고(카밧에 따른 넘버링), a)의 제1 Fab 분자의 불변 도메인 CH1에서 위치 147의 아미노산은 글루탐산(E)에 의해 치환되고(카밧 EU 인덱스에 따른 넘버링), 위치 213의 아미노산은 글루참산(E)에 의해 치환된다(카밧 EU 인덱스에 따른 넘버링).
훨씬 더 특정한 실시양태에서, a)의 제1 Fab 분자의 불변 도메인 CL에서 위치 124의 아미노산은 리신(K)에 의해 치환되고(카밧에 따른 넘버링), 위치 123의 아미노산 아르기닌(R)에 의해 치환되고(카밧에 따른 넘버링), a)의 제1 Fab 분자의 불변 도메인 CH1에서 위치 147의 아미노산은 글루탐산(E)에 의해 치환되고(카밧 EU 인덱스에 따른 넘버링), 위치 213 아미노산은 글루탐산(E)에 의해 치환된다(카밧 EU 인덱스에 따른 넘버링).
F. 키메라 항원 수용체
인공 T 세포 수용체(키메라 T 세포 수용체, 키메라 면역수용체, 키메라 항원 수용체(CAR)로도 알려짐)는 임의의 특이성을 면역 효과기 세포에 이식하는 조작된 수용체이다. 일반적으로, 이러한 수용체는 레트로바이러스 벡터에 의해 촉진되는 코딩 서열의 전달과 함께 T 세포에 단일클론 항체의 특이성을 이식하는데 사용된다. 이러한 방식으로, 많은 수의 표적 특이적 T 세포가 입양 세포 전달을 위해 생성될 수 있다. 이 접근법의 1상 임상 연구는 효능을 보여준다.
이들 분자의 가장 일반적인 형태는 CD3-제타 막관통 및 엔도도메인에 융합된 단일클론 항체로부터 유래된 단일 사슬 가변 단편(scFv)의 융합체이다. 이러한 분자는 표적의 scFv에 의한 인식에 대한 반응으로 제타 신호의 전달을 초래한다. 이러한 작제물의 예는 하이브리도마 14g2a(디시알로강글리오사이드 GD2를 인식함)에서 유래된 scFv의 융합체인 14g2a-제타이다. T 세포가 이 분자를 발현할 때(보통 온코레트로바이러스 벡터 형질도입에 의해 달성됨), T 세포는 GD2를 발현하는 표적 세포(예를 들어, 신경모세포종 세포)를 인식하고 사멸시킨다. 악성 B 세포를 표적화하기 위해 연구자들은 B 계통 분자인 CD19에 특이적인 키메라 면역 수용체를 사용하여 T 세포의 특이성을 재유도했다.
면역글로불린 중쇄 및 경쇄의 가변 부분은 가요성 링커에 의해 융합되어 scFv를 형성한다. 이 scFv는 초기 단백질을 소포체 및 후속 표면 발현으로 유도하는 신호 펩타이드가 선행된다(이는 절단됨). 가요성 스페이서는 scFv가 항원 결합을 가능하게 하기 위해 다른 방향으로 배향되도록 한다. 막관통 도메인은 일반적으로 세포내로 돌출되어 적절한 신호를 전달하는 신호전달 엔도도메인의 원래 분자에서 유래된 통상적인 소수성 알파 나선이다.
유형 I 단백질은 실제로 그 사이에 막관통 알파 나선에 의해 연결된 2개의 단백질 도메인이다. 막관통 도메인이 통과하는 세포막 지질 이중층은 외부 부분(엑토도메인)에서 내부 부분(엔도도메인)을 단리하는 역할을 한다. 한 단백질의 엑토도메인을 다른 단백질의 엔도도메인에 부착하면 전자의 인식을 후자의 신호와 조합하는 분자가 생성된다는 것은 그리 놀라운 일이 아니다.
엑토도메인. 신호 펩타이드는 초기 단백질을 소포체로 유도한다. 이는 수용체가 글리코실화되고 세포막에 고정되는 경우 필수적이다. 모든 진핵생물 신호 펩타이드 서열은 일반적으로 잘 작동한다. 일반적으로 대부분의 아미노 말단 성분에 고유하게 부착된 신호 펩타이드가 사용된다(예를 들어, 경쇄-링커-중쇄 방향을 갖는 scFv에서는 경쇄의 고유 신호가 사용됨).
항원 인식 도메인은 일반적으로 scFv이다. 그러나 많은 대안이 있다. 천연 T-세포 수용체(TCR) 알파 및 베타 단일 사슬의 항원 인식 도메인은 간단한 엑토도메인(예를 들어, HIV 감염 세포를 인식하는 CD4 엑토도메인)과 연결된 사이토카인(이는 사이토카인 수용체를 지닌 세포의 인식을 유발함)과 같은 더 많은 외부 인식 성분을 보유하는 것으로 기재되었다. 사실, 소정의 표적에 높은 친화도로 결합하는 거의 모든 것이 항원 인식 영역으로 사용될 수 있다.
스페이서 영역은 항원 결합 도메인을 막관통 도메인에 연결한다. 항원 인식을 용이하게 하기 위해 항원 결합 도메인이 다른 방향으로 배향될 수 있도록 충분히 가변적이어야 한다. 가장 단순한 형태는 IgG1의 힌지 영역이다. 대안으로는 면역글로불린의 CH2CH3 영역과 CD3의 일부가 포함된다. 대부분의 scFv 기반 작제물의 경우, IgG1 힌지로 충분한다. 그러나 최적의 스페이서는 종종 경험적으로 결정되어야 한다.
막관통 도메인. 막관통 도메인은 막을 가로지르는 소수성 알파 나선이다. 일반적으로, 엔도도메인의 가장 막 근위 성분의 막관통 도메인이 사용된다. 흥미롭게도 CD3-제타 막관통 도메인을 사용하면 천연 CD3-제타 막관통 하전 아스파라긴산 잔기의 존재에 의존하는 인자인 천연 TCR에 인공 TCR이 혼입될 수 있다. 다른 막관통 도메인은 다른 수용체 안정성을 초래한다. CD28 막관통 도메인은 밝게 발현되고 안정한 수용체를 생성한다.
엔도도메인. 이는 수용체의 "작용 말단"이다. 항원 인식 후 수용체가 클러스터링되고 신호가 세포로 전달된다. 가장 일반적으로 사용되는 엔도도메인 성분은 3개의 ITAM을 포함하는 CD3-제타이다. 이는 항원이 결합된 후 활성화 신호를 T 세포에 전달한다. CD3-제타는 완전히 적격의 활성화 신호를 제공하지 않을 수 있으며 추가 공자극 신호가 필요하다.
"1세대" CAR은 통상적으로 내인성 TCR로부터의 신호의 1차 전달인자인 CD3 ξ-사슬로부터의 세포내 도메인을 가졌다. "2세대" CAR은 T 세포에 추가 신호를 제공하기 위해 다양한 공자극 단백질 수용체(예를 들어, CD28, 41BB, ICOS)의 세포내 신호전달 도메인을 CAR의 세포질 꼬리에 추가한다. 전임상 연구에 따르면 2세대 CAR 설계는 T 세포의 항종양 활성을 향상시키는 것으로 나타났다. 보다 최근의 "3세대" CAR은 CD3z-CD28-41BB 또는 CD3z-CD28-OX40과 같은 여러 신호전달 도메인을 조합하여 효능을 더욱 향상시킨다.
G. ADC
항체 약물 접합체 또는 ADC는 감염성 질병이 있는 인간의 치료를 위한 표적 요법으로 설계된 신규한 클래스의 매우 강력한 생물약제 약물이다. ADC는 불안정한 결합이 있는 안정한 화학적 링커를 통해 생물학적 활성 세포독성/항바이러스 함유물 또는 약물에 연결된 항체 (전체 mAb 또는 항체 단편, 예컨대 단일-사슬 가변 단편, 또는 scFv)로 이루어진 복합체 분자이다. 항체 약물 접합체는 생체접합체 및 면역접합체의 예이다.
단일클론 항체의 고유한 표적화 능력을 세포독성 약물의 암-사멸 능력과 조합함으로써, 항체-약물 접합체는 건강한 조직과 병에 걸린 조직 사이의 감응성 구별을 가능하게 한다. 이는 기존의 전신 접근법과 달리 항체-약물 접합체가 감염된 세포를 표적화하고 공격하여 건강한 세포가 덜 심각하게 영향을 받는다는 것을 의미한다.
ADC 기반 항종양 요법의 개발에서, 항암 약물(예를 들어, 세포 독소 또는 세포독소)은 특정 세포 마커(예를 들어, 이상적으로는 감염된 세포 내 또는 감염된 세포 상에 존재함)를 특이적으로 표적화하는 항체에 연결된다. 항체는 이러한 단백질을 체내에서 추적하여 암세포 표면에 부착한다. 항체와 표적 단백질(항원) 사이의 생화학적 반응은 종양 세포에서 신호를 촉발하고, 이 신호는 세포독소와 함께 항체를 흡수하거나 내재화한다. ADC가 내재화되면 세포독성 약물이 방출되어 세포를 사멸시키거나 바이러스 복제를 손상시킨다. 이러한 표적화로 인해 이상적으로 약물은 부작용이 더 적고 다른 약물보다 치료 범위가 더 넓다.
항체와 세포독성/항바이러스제 사이의 안정한 연결은 ADC의 중요한 양상이다. 링커는 이황화물, 히드라존 또는 펩타이드(절단 가능) 또는 티오에테르(절단 불가능)를 포함하는 화학적 모티프를 기반으로 하며 세포독성제의 분포 및 표적 세포로의 전달을 제어한다. 절단 가능한 유형 및 절단 불가능한 유형의 링커는 전임상 및 임상 시험에서 안전한 것으로 입증되었다. 브렌툭시맙 베도틴(Brentuximab vedotin)에는 인간 특이적 CD30 양성 악성 세포에 합성 항종양제인 강력하고 독성이 강한 항미세소관제인 모노메틸 아우리스타틴 (Monomethyl auristatin) E 또는 MMAE를 전달하는 효소 감응성 절단 가능한 링커가 포함된다. MMAE는 튜불린의 중합을 차단하여 세포분열을 억제하는 독성이 높기 때문에 단일제제 화학치료제로는 사용할 수 없다. 그러나 항-CD30 단일클론 항체(cAC10, 종양 괴사 인자 또는 TNF 수용체의 세포막 단백질)에 연결된 MMAE의 조합은 세포외액에서 안정하고 카텝신에 의해 절단될 수 있고 치료에 안전한 것으로 입증되었다. 또 다른 승인된 ADC인 트라스투주맙 엠탄신(Trastuzumab emtansine)은 마이탄신(Maytansine)의 유도체인 미세소관 형성 억제제 메르탄신(mertansine)(DM-1)과 항체 트라스투주맙(Herceptin®/Genentech/Roche)이 안정한 비절단 링커에 의해 부착된 조합이다.
더 우수하고 안정한 링커의 이용 가능성은 화학 결합의 기능을 변화시켰다. 절단 가능 또는 절단 불가능한 링커 유형은 세포독성(항암) 약물에 특정 특성을 부여한다. 예를 들어, 절단 불가능한 링커는 약물을 세포내에 유지시킨다. 결과적으로 전체 항체, 링커 및 세포독성제는 항체가 아미노산 수준으로 분해되는 표적화된 암세포로 유입된다. 생성된 복합체 - 아미노산, 링커 및 세포독성제는 이제 활성 약물이 된다. 이와 달리, 절단 가능한 링커는 세포독성제를 방출하는 숙주 세포에서 효소에 의해 촉매화된다.
현재 개발 중인 다른 유형의 절단 가능한 링커는 세포독성/항바이러스 약물과 절단 부위 사이에 추가 분자를 추가한다. 이 링커 기술을 통해 연구원은 절단 역학 변화에 대한 걱정 없이 더 가변적으로 ADC를 생성할 수 있다. 연구원들은 또한 펩타이드에서 아미노산을 시퀀싱하는 방법인 Edman 분해를 기반으로 하는 신규한 펩타이드 절단 방법을 개발하고 있다. ADC 개발의 향후 방향에는 안정성 및 치료 지수를 더욱 개선하기 위한 부위 특이적 접합(TDC) 및 α 방출 면역접합체 및 항체 접합 나노입자의 개발도 포함된다.
H. BiTES
이중특이적 T-세포 결합인자(BiTE)는 항암 약물로서의 사용을 위해 조사되는 인공 이중특이적 단일클론 항체의 클래스이다. 이는 감염된 세포에 대한 숙주의 면역계, 보다 구체적으로 T 세포의 세포독성 활성을 유도한다. BiTE는 Micromet AG의 등록 상표이다.
BiTE는 약 55킬로달톤의 단일 펩타이드 사슬에 서로 다른 항체의 2개의 단일 사슬 가변 단편(scFv) 또는 4개의 상이한 유전자의 아미노산 서열로 구성된 융합 단백질이다. scFv 중 하나는 CD3 수용체를 통해 T 세포에 결합하고 다른 하나는 특정 분자를 통해 감염된 세포에 결합한다.
다른 이중특이적 항체와 마찬가지로 일반 단일클론 항체와 달리 BiTE는 T 세포와 표적 세포 사이에 연결을 형성한다. 이는 T 세포가 MHC I 또는 공자극 분자의 존재와 무관하게 퍼포린(perforin) 및 그랜자임(granzyme)과 같은 단백질을 생산함으로써 감염된 세포에 세포독성/항바이러스 활성을 발휘하도록 한다. 이 단백질은 감염된 세포에 유입되어 세포의 세포 사멸을 개시한다. 이 작용은 감염된 세포에 대한 T 세포 공격 동안 관찰되는 생리학적 과정을 모방한다.
I. 인트라바디
특정 실시양태에서, 항체는 세포내부의 작용에 적합한 재조합 항체이며, 이러한 항체는 "인트라바디"로 알려져 있다. 이러한 항체는 세포내 단백질 수송을 변경하고, 효소 기능을 방해하고, 단백질-단백질 또는 단백질-DNA 상호작용을 차단하는 것과 같은 다양한 기전에 의해 표적 기능을 방해할 수 있다. 많은 면에서 이의 구조는 위에서 논의한 단일 사슬 및 단일 도메인 항체의 구조를 모방하거나 이와 유사하다. 실제로, 단일 전사체/단일 사슬은 표적 세포에서 세포내 발현을 가능하게 하고 세포막을 통한 단백질 수송을 보다 실현 가능하게 하는 중요한 기능이다. 그러나 추가 기능이 필요하다.
인트라바디 치료제의 구현에 영향을 미치는 두 가지 주요 문제는 세포/조직 표적화를 포함하는 전달 및 안정성이다. 전달과 관련하여 조직 유도 전달, 세포 유형 특이적 프로모터의 사용, 바이러스 기반 전달 및 세포 투과성/막 전위 펩타이드의 사용과 같은 다양한 접근법이 사용되었다. 안정성과 관련하여 이 접근법은 일반적으로 파지 디스플레이를 포함하고 공통 서열의 서열 성숙 또는 발달 또는 더 많은 유도된 변형, 예컨대 삽입 안정화 서열(예를 들어, Fc 영역, 샤페론 단백질 서열, 류신 지퍼) 및 이황화 대체/변형을 포함할 수 있는 방법을 포함하는 무차별 대입에 의한 스크리닝이다.
인트라바디가 요구할 수 있는 추가 특징은 세포내 표적화를 위한 신호이다. 세포질, 핵, 미토콘드리아 및 ER과 같은 세포내 영역에 대한 인트라바디(또는 다른 단백질)를 표적화할 수 있는 벡터가 설계되었고 상업적으로 입수가능하다(문헌[Invitrogen Corp.; Persic et al., 1997]).
세포에 유입되는 능력으로 인해, 인트라바디는 다른 유형의 항체가 달성할 수 없는 추가 용도를 갖는다. 본 발명의 항체의 경우, 살아있는 세포에서 MUC1 세포질 도메인과 상호작용하는 능력은 신호전달 기능(다른 분자에 대한 결합) 또는 올리고머 형성과 같은 MUC1 CD와 관련된 기능을 방해할 수 있다. 특히, 이러한 항체는 MUC1 이량체 형성을 억제하기 위해 사용될 수 있는 것으로 고려된다.
J. 정제
특정 실시양태에서, 본 개시내용의 항체는 정제될 수 있다. 본 명세서에 사용되는 바와 같이, 용어 "정제된"은 단백질이 천연적으로 얻을 수 있는 상태에 비해 어느 정도로 정제된 다른 성분으로부터 단리 가능한 조성물을 지칭하는 것으로 의도된다. 따라서 정제된 단백질은 천연적으로 발생할 수 있는 환경으로부터 부재하는 단백질을 지칭하기도 한다. "실질적으로 정제된"이라는 용어가 사용되는 경우, 이러한 개시는 단백질 또는 펩타이드가 조성물 내 단백질의 약 50%, 약 60%, 약 70%, 약 80%, 약 90%, 약 95% 이상을 구성하는 것과 같이, 조성물의 주요 성분을 형성하는 조성물을 지칭할 것이다.
단백질 정제 기술은 당업자에게 잘 알려져 있다. 이러한 기술은 한 수준에서 세포 환경을 폴리펩타이드 및 비-폴리펩타이드 분획으로 미정제 분별하는 단계를 포함한다. 폴리펩타이드를 다른 단백질로부터 분리한 후, 대상 폴리펩타이드는 크로마토그래피 및 전기영동 기술을 사용하여 추가로 정제하여 부분적 또는 완전한 정제(또는 균질성을 위한 정제)를 달성할 수 있다. 순수한 펩타이드의 제조에 특히 적합한 분석 방법은 이온 교환 크로마토그래피, 배제 크로마토그래피; 폴리아크릴아미드 겔 전기영동; 등전 초점이다. 단백질 정제를 위한 다른 방법에는 황산암모늄, PEG, 항체 등에 의하거나 열 변성에 의한 침전 후 원심분리; 겔 여과, 역상, 수산화인회석 및 친화도 크로마토그래피; 및 이러한 기술과 다른 기술의 조합을 포함한다.
본 개시내용의 항체 정제에서, 원핵생물 또는 진핵생물 발현 시스템에서 폴리펩타이드를 발현시키고 변성 조건을 사용하여 단백질을 추출하는 단계가 바람직할 수 있다. 폴리펩타이드는 폴리펩타이드의 태깅된 부분에 결합하는 친화도 컬럼을 사용하여 다른 세포 성분으로부터 정제될 수 있다. 당업계에 일반적으로 알려진 바와 같이, 다양한 정제 단계를 수행하는 순서가 변화될 수 있거나 특정 단계가 생략될 수 있으며, 여전히 실질적으로 정제된 단백질 또는 펩타이드의 제조를 위한 적합한 방법이 구현되는 것으로 고려된다.
일반적으로, 완전한 항체는 항체의 Fc 부분에 결합하는 제제(즉, 단백질 A)를 사용하여 분획화된다. 대안적으로, 항원은 적절한 항체를 동시에 정제하고 선택하기 위해 사용될 수 있다. 이러한 방법은 종종 컬럼, 필터 또는 비드와 같은 지지체에 결합된 선택제를 활용한다. 항체는 지지체에 결합되고 오염물질은 제거되고(예를 들어, 세척), 항체는 조건(소금, 열 등)을 적용하여 방출된다.
단백질 또는 펩타이드의 정제 정도를 정량화하는 다양한 방법은 본 개시내용에 비추어 당업자에게 인식될 것이다. 여기에는 예를 들어 활성 분획의 고유 활성을 결정하거나 SDS/PAGE 분석을 통해 분획 내 폴리펩타이드의 양을 평가하는 것이 포함된다. 분획의 순도를 평가하는 또 다른 방법은 분획의 고유 활성을 계산하여 초기 추출물의 고유 활성과 비교하여 순도를 계산하는 것이다. 활성의 양을 나타내는데 사용되는 실제 단위는 물론 정제 후에 선택된 특정 분석 기술 및 발현된 단백질 또는 펩타이드가 검출 가능한 활성을 나타내는지에 따라 달라질 것이다.
폴리펩타이드의 이동은 SDS/PAGE의 상이한 조건에 따라 때때로 상당히 다양할 수 있는 것으로 알려져 있다(문헌[Capaldi et al., 1977]). 따라서, 상이한 전기영동 조건하에서 정제되거나 부분적으로 정제된 발현 산물의 겉보기 분자량이 변할 수 있음을 이해할 것이다.
III. SARS-CoV-2 감염의 능동/수동 면역 및 치료/예방
A. 제형 및 투여
본 개시내용은 항-SARS-CoV-2 바이러스 항체 및 이를 생성하기 위한 항원을 포함하는 약제학적 조성물을 제공한다. 이러한 조성물은 예방적 또는 치료적 유효량의 항체 또는 이의 단편, 또는 펩타이드 면역원, 및 약제학적으로 허용 가능한 담체를 포함한다. 특정 실시양태에서, 용어 "약제학적으로 허용 가능한"은 미국 연방 또는 주 정부의 규제 기관에 의해 승인되거나 미국 약전 또는 동물, 보다 특히 인간에서의 사용에 대해 일반적으로 인정되는 기타 약전에 열거됨을 의미한다. 용어 "담체"는 치료제가 함께 투여되는 희석제, 부형제 또는 비히클을 지칭한다. 이러한 약제학적 담체는 멸균 액체, 예컨대 물 및 석유, 동물성, 식물성 또는 합성 유래의 오일을 포함한 오일, 예를 들어 땅콩유, 대두유, 광유, 참깨유 등일 수 있다. 물은 약제학적 조성물이 정맥내 투여될 때 특정한 담체이다. 식염수, 덱스트로스 및 글리세롤 수용액도 특히 주사 용액의 경우 액체 담체로 사용될 수 있다. 다른 적합한 약제학적 부형제는 전분, 글루코스, 락토스, 수크로스, 젤라틴, 맥아, 쌀, 밀가루, 백악, 실리카겔, 스테아르산나트륨, 모노스테아르산글리세롤, 탈크, 염화나트륨, 건조 탈지유, 글리세롤, 프로필렌, 글리콜, 물, 에탄올 등을 포함한다.
적절한 경우, 조성물은 또한 소량의 습윤제 또는 유화제, 또는 pH 완충제를 포함할 수 있다. 이러한 조성물은 용액, 현탁액, 에멀젼, 정제, 환제, 캡슐, 분말, 지속 방출 제형 등의 형태를 취할 수 있다. 경구 제형은 만니톨, 락토스, 전분, 스테아르산마그네슘, 사카린나트륨, 셀룰로스, 탄산마그네슘 등의 약제학적 등급과 같은 표준 담체를 포함할 수 있다. 적합한 약제의 예는 문헌["Remington's Pharmaceutical Sciences"]에 기재되어 있다. 이러한 조성물은 환자에게 적절한 투여를 위한 형태를 제공하기 위해 적절한 양의 담체와 함께 예방적 또는 치료적 유효량의 항체 또는 이의 단편, 바람직하게는 정제된 형태를 포함할 것이다. 제형은 경구, 정맥내, 동맥내, 협측, 비강내, 분무, 기관지 흡입, 직장내, 질내, 국소 또는 기계적 호흡에 의해 전달될 수 있는 투여 방식에 적합해야 한다.
개시된 것과 같은 항체가 SARS-CoV-2 감염의 위험이 있는 대상체에서 생체내에서 생산되는 활성 백신이 또한 구상된다. 이러한 백신은 비경구 투여용으로 제형화될 수 있으며, 예를 들어 피내, 정맥내, 근육내, 피하 또는 심지어 복강내 경로를 통한 주사용으로 제형화될 수 있다. 피내 및 근육내 경로에 의한 투여가 고려된다. 대안적으로 백신은 점막에 직접 국소 경로, 예를 들어 점비제, 흡입, 분무기, 또는 직장내 또는 질 전달을 통해 투여될 수 있다. 약제학적으로 허용 가능한 염은 산염 및 예를 들어 염산 또는 인산과 같은 무기산, 또는 아세트산, 옥살산, 타르타르산, 만델산 등과 같은 유기산으로 형성된 염을 포함한다. 유리 카복실기로 형성된 염은 또한 예를 들어 나트륨, 칼륨, 암모늄, 칼슘 또는 수산화 제2철과 같은 무기 염기, 및 이소프로필아민, 트리메틸아민, 2-에틸아미노 에탄올, 히스티딘, 프로카인 등과 같은 유기 염기로부터 유래될 수 있다.
인공적으로 획득된 수동 면역으로 알려진 항체의 수동 전달은 일반적으로 정맥내 또는 근육내 주사의 사용을 수반할 것이다. 항체의 형태는 인간 또는 동물의 혈장 또는 혈청, 정맥내(IVIG) 또는 근육내(IG) 사용을 위한 풀링된 인간 면역글로불린, 면역화된 또는 질병으로부터 회복된 공여체로부터의 고역가 인간 IVIG 또는 IG 및 단일클론 항체(MAb)일 수 있다. 이러한 면역은 일반적으로 짧은 기간 동안만 지속되며 특히 비인간 유래의 감마 글로불린으로 인한 과민 반응 및 혈청병의 잠재적 위험이 있다. 그러나 수동 면역은 즉각적인 보호를 제공한다. 항체는 주사에 적합한, 즉 멸균되고 주사기에 적합한 담체에 제형화될 것이다.
일반적으로, 본 개시내용의 조성물의 성분은 단위 투여 형태로 개별적으로 또는 함께 혼합되어, 예를 들어 건조 동결건조 분말 또는 물이 없는 농축물로서 활성제의 양을 나타내는 앰플(ampoule) 또는 사셰(sachette)와 같은 밀폐된 밀봉 용기에 공급된다. 조성물이 주입에 의해 투여되는 경우, 멸균 약제학적 등급의 물 또는 식염수를 포함하는 주입 병과 함께 분배될 수 있다. 조성물이 주사에 의해 투여되는 경우, 주사용 멸균수 또는 식염수의 앰플이 제공될 수 있어 투여 전에 성분이 혼합될 수 있다.
본 개시내용의 조성물은 중성 또는 염 형태로 제형화될 수 있다. 약제학적으로 허용 가능한 염은 염산, 인산, 아세트산, 옥살산, 타르타르산 등으로부터 유래된 것과 같은 음이온으로 형성된 염, 및 나트륨, 칼륨, 암모늄, 칼슘, 수산화제이철, 이소프로필아민, 트리에틸아민, 2-에틸아미노에탄올, 히스티딘, 프로카인 등으로부터 유래된 것과 같은 양이온으로 형성된 염을 포함한다.
2. ADCC
항체-의존성 세포-매개 세포독성(ADCC)은 면역 효과기 세포에 의한 항체-코팅된 표적 세포의 용해를 유도하는 면역 기전이다. 표적 세포는 일반적으로 Fc 영역의 N-말단인 단백질 부분을 통해 항체 또는 Fc 영역을 포함하는 이의 단편이 특이적으로 결합하는 세포이다. "항체 의존성 세포 매개 세포독성(ADCC)이 증가/감소된 항체"는 당업자에게 공지된 임의의 적합한 방법에 의해 측정된 바와 같이 ADCC가 증가/감소된 항체를 의미한다.
본 명세서에 사용되는 바와 같이, 용어 "증가/감소된 ADCC"는 위에서 정의한 ADCC의 기전에 의해 표적 세포를 둘러싸는 배지에서 소정의 항체 농도에서 소정의 시간에 용해되는 표적 세포 수의 증가/감소, 및/또는 ADCC의 기전에 의해 소정의 시간에 소정의 수의 표적 세포의 용해를 달성하는데 필요한 표적 세포를 둘러싼 배지에서 항체 농도의 감소/증가로 정의된다. ADCC의 증가/감소는 동일한 표준 생산, 정제, 제형 및 저장 방법(이는 당업자에게 공지됨)을 사용하여 동일한 유형의 숙주 세포에 의해 생산된 동일한 항체에 의해 매개되지만, 조작되지 않은 ADCC에 상대적이다. 예를 들어, 본 명세서에 기재된 방법에 의해 (예를 들어, 글리코실트랜스퍼라제, GnTIII 또는 다른 글리코실트랜스퍼라제를 발현하기 위해) 변경된 패턴의 글리코실화를 갖도록 조작된 숙주 세포에 의해 생산된 항체에 의해 매개되는 ADCC의 증가는 동일한 유형의 조작되지 않은 숙주 세포에 의해 생산된 동일한 항체에 의해 매개되는 ADCC에 상대적이다.
3. CDC
보체 의존성 세포독성(CDC)은 보체 시스템의 기능이다. 면역계의 항체나 세포의 개입 없이 병원체의 막을 손상시켜 병원체를 사멸시키는 것은 면역계의 과정이다. 세 가지 주요 과정이 있다. 세 가지 모두 치명적인 콜로이드 삼투 부종, 즉 CDC를 유발하는 병원체에 하나 이상의 막 공격 복합체(MAC)를 삽입한다. 이는 항체 또는 항체 단편이 항바이러스 효과를 갖는 기전 중 하나이다.
IV. 항체 접합체
본 개시내용의 항체는 항체 접합체를 형성하기 위해 적어도 하나의 제제에 연결될 수 있다. 진단제 또는 치료제로서의 항체 분자의 효능을 증가시키기 위해, 적어도 하나의 적절한 분자 또는 모이어티를 연결하거나 공유 결합하거나 복합체화하는 것이 통상적이다. 이러한 분자 또는 모이어티는 다음에 제한되는 것은 아니나, 적어도 하나의 효과기 또는 리포터 분자일 수 있다. 효과기 분자는 적절한 활성, 예를 들어 세포독성 활성을 갖는 분자를 포함한다. 항체에 부착된 효과기 분자의 비제한적 예는 독소, 항종양제, 치료 효소, 방사성핵종, 항바이러스제, 킬레이트제, 사이토카인, 성장 인자, 및 올리고- 또는 폴리뉴클레오타이드를 포함한다. 이와 달리, 리포터 분자는 분석을 사용하여 검출될 수 있는 임의의 모이어티로 정의된다. 항체에 접합된 리포터 분자의 비제한적인 예는 효소, 방사성 표지, 합텐, 형광 표지, 인광 분자, 화학발광 분자, 발색단, 광친화도 분자, 착색 입자 또는 리간드, 예컨대 비오틴을 포함한다.
항체 접합체는 일반적으로 진단제로서 사용하기에 바람직하다. 항체 진단은 일반적으로 다양한 면역분석과 같은 시험관내 진단에 사용되는 것과 일반적으로 "항체 지시 영상"으로 알려진 생체내 진단 프로토콜에 사용되는 것의 두 가지 클래스에 속한다. 많은 적절한 영상화제가 항체에 부착하는 방법과 같이 당업계에 공지되어 있다(예를 들어, 미국 특허 제 5,021,236호, 제 4,938,948호 및 제 4,472,509호 참조). 사용된 영상화 모이어티는 상자성 이온, 방사성 동위원소, 형광색소, NMR 검출 가능한 물질 및 X선 영상화제일 수 있다.
상자성 이온의 경우, 예로서 크롬(III), 망간(II), 철(III), 철(II), 코발트(II), 니켈(II), 구리(II), 네오디뮴(III), 사마륨(III), 이테르븀(III), 가돌리늄(III), 바나듐(II), 테르븀(III), 디스프로슘(III), 홀뮴(III) 및/또는 에르븀(III)과 같은 이온이 언급되며, 가돌리늄이 특히 바람직하다. X선 영상과 같은 다른 상황에서 유용한 이온에는 다음에 제한되는 것은 아니나, 란탄(III), 금(III), 납(II), 특히 비스무트(III)가 포함된다.
치료 및/또는 진단 적용을 위한 방사성 동위원소의 경우, 아스타틴211, 14탄소, 51크롬, 36염소, 57코발트, 58코발트, 구리67, 152Eu, 갈륨67, 3수소, 요오드123, 요오드125, 요오드131, 인듐111, 59철, 32인, 레늄186, 레늄188, 75셀레늄, 35황, 테크니슘99m 및/또는 이트륨90이 언급된다. 125I는 특정 실시양태에서 사용하기에 종종 바람직하며, 테크니슘99m 및/또는 인듐111은 낮은 에너지와 장기 범위 검출에 대한 적합성으로 인해 종종 바람직하다. 본 개시내용의 방사성 표지된 단일클론 항체는 당업계에 공지된 방법에 따라 생산될 수 있다. 예를 들어, 단일클론 항체는 요오드화나트륨 및/또는 요오드화칼륨 및 차아염소산나트륨과 같은 화학적 산화제 또는 락토페록시다제와 같은 효소적 산화제와의 접촉에 의해 요오드화될 수 있다. 본 개시내용에 따른 단일클론 항체는 리간드 교환 과정, 예를 들어 퍼테크네이트를 제1주석 용액으로 환원시키고, 환원된 테크네튬을 세파덱스 컬럼 상에 킬레이트화하고, 항체를 이 컬럼에 적용함으로써 테크네튬99m으로 표지될 수 있다. 대안적으로, 예를 들어 퍼테크네이트, SNCl2와 같은 환원제, 나트륨-칼륨 프탈레이트 용액과 같은 완충 용액 및 항체를 인큐베이션함으로써 직접 표지 기술을 사용할 수 있다. 금속 이온으로 존재하는 방사성 동위원소를 항체에 결합시키는데 자주 사용되는 중간 작용기는 디에틸렌트리아민펜타아세트산(DTPA) 또는 에틸렌디아민테트라아세트산(EDTA)이다.
접합체로서 사용하기 위해 고려되는 형광 표지 중에는 알렉사(Alexa) 350, 알렉사 430, AMCA, BODIPY 630/650, BODIPY 650/665, BODIPY-FL, BODIPY-R6G, BODIPY-TMR, BODIPY-TRX, 카스카드 블루(Cascade Blue), Cy3, Cy5,6-FAM, 플루오레세인 이소티오시아네이트(Fluorescein Isothiocyanate), HEX, 6-JOE, Oregon Green 488, 오레그온 그린(Oregon Green) 500, 오레그온 그린 514, 퍼시픽 블루(Pacific Blue), REG, 로다민 그린(Rhodamine Green), 로다민 레드(Rhodamine Red), 레노그라핀(Renographin), ROX, TAMRA, TET, 테트라메틸로다민(Tetramethylrhodamine), 및/또는 텍사스 레드(Texas Red)가 포함된다.
본 개시내용에서 고려되는 추가 유형의 항체는 주로 시험관내 사용을 목적으로 하는 것이며, 항체는 2차 결합 리간드 및/또는 발색 기질과 접촉시 착색 산물을 생성하는 효소(효소 태그)에 연결된다. 적합한 효소의 예는 우레아제, 알칼리성 포스파타제, (양고추냉이) 과산화수소 또는 글루코스 산화효소를 포함한다. 바람직한 2차 결합 리간드는 비오틴 및 아비딘 및 스트렙타비딘 화합물이다. 이러한 표지의 사용은 당업자에게 잘 알려져 있으며, 예를 들어 미국 특허 제 3,817,837호, 제 3,850,752호, 제 3,939,350호, 제 3,996,345호, 제 4,277,437호, 제 4,275,149호 및 제 4,366,241호에 기재되어 있다.
항체에 대한 분자의 부위-특이적 부착의 또 다른 공지된 방법은 항체와 합텐 기반 친화도 표지의 반응을 포함한다. 기본적으로 합텐 기반 친화도 표지는 항원 결합 부위의 아미노산과 반응하여 이 부위를 파괴하고 특정 항원 반응을 차단한다. 그러나, 이는 항체 접합체에 의한 항원 결합의 손실을 초래하기 때문에 유리하지 않을 수 있다.
아지도기를 포함하는 분자는 또한 저강도 자외선에 의해 생성되는 반응성 니트렌 중간체를 통해 단백질에 공유 결합을 형성하는데 사용될 수 있다(문헌[Potter and Haley, 1983]). 특히, 퓨린 뉴클레오타이드의 2- 및 8-아지도 유사체는 미정제 세포 추출물에서 뉴클레오타이드 결합 단백질을 확인하기 위한 부위 지정 광프로브로 사용되었다(문헌[Owens & Haley, 1987; Atherton et al., 1985]). 2- 및 8-아지도 뉴클레오타이드는 또한 정제된 단백질의 뉴클레오타이드 결합 도메인을 매핑하는데 사용되었으며(문헌[Khatoon et al., 1989; King et al., 1989; Dholakia et al., 1989]), 항체 결합제로 사용될 수 있다.
항체의 접합체 모이어티에 대한 부착 또는 접합을 위한 여러 방법이 당업계에 공지되어 있다. 일부 부착 방법은 예를 들어 항체에 부착된 유기 킬레이트제, 예컨대 디에틸렌트리아민펜타아세트산 무수물(DTPA); 에틸렌트리아민테트라아세트산; N-클로로-p-톨루엔술폰아미드; 및/또는 테트라클로로-3α-6α-디페닐글리코릴-3을 사용한 금속 킬레이트 착물의 사용을 포함한다(미국 특허 제 4,472,509호 및 제 4,938,948호). 단일클론 항체는 또한 글루타르알데하이드 또는 페리오데이트와 같은 연결제의 존재 하에 효소와 반응할 수 있다. 플루오레세인 마커가 있는 접합체는 이러한 연결제의 존재 하에 또는 이소티오시아네이트와의 반응에 의해 제조된다. 미국 특허 제 4,938,948호에서, 유방 종양의 영상화는 단일클론 항체를 사용하여 달성되고 검출 가능한 영상화 모이어티는 메틸-p-하이드록시벤즈이미데이트 또는 N-숙신이미딜-3-(4-하이드록시페닐)프로피오네이트와 같은 링커를 사용하여 항체에 결합된다.
다른 실시양태에서, 항체 결합 부위를 변경하지 않는 반응 조건을 사용하여 면역글로불린의 Fc 영역에 술프히드릴기를 선택적으로 도입함으로써 면역글로불린의 유도체화가 고려된다. 이 방법에 따라 생산된 항체 접합체는 개선된 수명, 특이성 및 감응성을 나타내는 것으로 개시되어 있다(미국 특허 제 5,196,066호, 참조로 본 명세서에 포함됨). 리포터 또는 효과기 분자가 Fc 영역의 탄수화물 잔기에 접합된 효과기 또는 리포터 분자의 부위 특이적 부착도 문헌에 개시되어 있다(문헌[O'Shannessy et al., 1987]). 이 접근법은 현재 임상 평가 중인 진단 및 치료적으로 유망한 항체를 생산하는 것으로 보고되었다.
V. 면역검출 방법
또 다른 실시양태에서, 본 개시내용은 SARS-CoV-2 및 이의 관련 항원을 결합, 정제, 제거, 정량화 및 달리 일반적으로 검출하기 위한 면역검출 방법에 관한 것이다. 이러한 방법은 통상적인 의미로 적용될 수 있지만, 다른 용도는 백신 및 기타 바이러스 스톡의 특질 제어 및 모니터링에 있을 것이며, 본 개시내용에 따른 항체는 바이러스의 항원의 양 또는 완전성(즉, 장기간 안정성)을 평가하는데 사용될 수 있다. 대안적으로, 본 방법은 적절한/적합한 반응성 프로파일에 대해 다양한 항체를 스크리닝하기 위해 사용될 수 있다.
다른 면역검출 방법은 대상체에서 SARS-CoV-2의 존재를 결정하기 위한 특이적 분석을 포함한다. 다양한 분석 형식이 고려되지만, 특히 타액, 혈액, 혈장, 가래, 정액 또는 소변과 같은 대상체로부터 얻은 유체에서 SARS-CoV-2를 검출하는데 사용되는 형식이 고려된다. 특히 정액은 SARS-CoV-2 검출을 위한 실행 가능한 샘플로 입증되었다(문헌[Purpura et al., 2016; Mansuy et al., 2016; Barzon et al., 2016; Gornet et al., 2016; Duffy et al., 2009; CDC, 2016; Halfon et al., 2010; Elder et al. 2005]). 이 분석은 가정 임신 테스트와 유사한 측방 유동 분석(아래 참조)을 포함하여 비의료(가정) 사용을 위해 유리하게 형식화될 수 있다. 이러한 분석은 가족 구성원의 대상체가 사용할 수 있도록 적절한 시약 및 지침이 포함된 키트 형태로 포장될 수 있다.
일부 면역검출 방법에는 효소 결합 면역흡착 분석(ELISA), 방사선면역분석(RIA), 면역방사측정 분석, 형광면역분석, 화학발광 분석, 생물발광 분석 및 웨스턴 블롯 등이 포함된다. 특히, 샘플의 특정 기생충 에피토프에 대한 SARS-CoV-2 항체의 검출 및 정량화를 위한 경쟁 분석도 제공된다. 다양한 유용한 면역검출 방법의 단계는 예를 들어 문헌[Doolittle 및 Ben-Zeev(1999), Gulbis 및 Galand(1993), De Jager et al. (1993), 및 Nakamura et al. (1987)]과 같은 과학 문헌에 기재되어 있다. 일반적으로, 면역결합 방법은 SARS-CoV-2를 포함하는 것으로 예상되는 샘플을 획득하고, 경우에 따라 면역복합체의 형성을 가능하게 하기에 효과적인 조건 하에 샘플을 본 개시내용에 따라 1차 항체와 접촉시키는 단계를 포함한다.
이러한 방법에는 샘플에서 SARS-CoV-2 또는 관련 항원을 정제하는 방법이 포함된다. 항체는 바람직하게는 컬럼 매트릭스 형태와 같은 고체 지지체에 연결될 것이고, SARS-CoV-2 또는 항원 성분을 포함하는 것으로 예상되는 샘플은 고정된 항체에 적용될 것이다. 부적절한 성분을 컬럼에서 세척하여 고정된 항체에 면역 복합체를 형성한 SARS-CoV-2 항원을 유지시키고, 그런 다음 컬럼에서 유기체 또는 항원을 제거하여 수집한다.
면역결합 방법은 또한 샘플에서 SARS-CoV-2 또는 관련 성분의 양의 검출 및 정량화 방법 및 결합 과정 동안 형성된 임의의 면역 복합체의 검출 및 정량화 방법을 포함한다. 여기에서 SARS-CoV-2 또는 그 항원을 포함하는 것으로 예상되는 샘플을 얻고 샘플을 SARS-CoV-2 또는 그 성분에 결합하는 항체와 접촉시킨 다음 특정 조건에서 형성된 면역 복합체의 양을 검출하고 정량화한다. 항원 검출과 관련하여 분석된 생물학적 샘플은 SARS-CoV-2 또는 SARS-CoV-2 항원을 포함하는 것으로 예상되는 임의의 샘플, 예를 들어 조직 절편 또는 표본, 균질화된 조직 추출물, 혈액 및 혈청을 포함하는 생물학적 유체, 또는 분변이나 소변과 같은 분비물일 수 있다.
면역 복합체(1차 면역 복합체)의 형성을 가능하게 하기에 충분한 기간 동안 효과적인 조건 하에 선택된 생물학적 샘플을 항체와 접촉시키는 것은 일반적으로 단순히 항체 조성물을 샘플에 첨가하고 항체가 면역 복합체를 형성하기에 충분한 시간 동안, 즉 SARS-CoV-2 또는 존재하는 항원에 결합하기에 충분한 시간 동안 혼합물을 인큐베이션하는 문제이다. 이 시간이 지나면 조직 절편, ELISA 플레이트, 도트 블롯 또는 웨스턴 블롯과 같은 샘플-항체 조성물을 일반적으로 세척하여 비특이적으로 결합된 항체 종을 제거하여 검출되는 1차 면역 복합체 내에서 특이적으로 결합된 항체만이 존재하도록 한다.
일반적으로, 면역복합체 형성의 검출은 당업계에 잘 알려져 있고 수많은 접근법의 적용을 통해 달성될 수 있다. 이러한 방법은 일반적으로 방사성, 형광성, 생물학적 및 효소적 태그와 같은 표지 또는 마커의 검출을 기반으로 한다. 이러한 표지의 사용에 관한 특허에는 미국 특허 제 3,817,837호, 제 3,850,752호, 제 3,939,350호, 제 3,996,345호, 제 4,277,437호, 제 4,275,149호 및 제 4,366,241호가 포함된다. 물론, 당업계에 공지된 바와 같이 2차 항체 및/또는 비오틴/아비딘 리간드 결합 배열과 같은 2차 결합 리간드의 사용을 통해 추가적인 이점을 발견할 수 있다.
검출에 사용된 항체를 그 자체로 검출가능한 표지에 연결할 수 있고, 그 다음에는 이 표지를 간단히 검출함으로써 조성물 내의 1차 면역 복합체의 양을 결정할 수 있다. 대안적으로, 1차 면역 복합체 내에서 결합되는 1차 항체를 항체에 대한 결합 친화도를 갖는 2차 결합 리간드에 의해 검출할 수 있다. 이러한 경우, 2차 결합 리간드를 검출 가능한 표지에 연결할 수 있다. 2차 결합 리간드는 그 자체가 종종 항체이며, 따라서 "2차" 항체로 지칭될 수 있다. 1차 면역 복합체를 2차 면역 복합체의 형성을 가능하게 하기에 충분한 시간 동안 효과적인 조건 하에 표지된 2차 결합 리간드 또는 항체와 접촉시킨다. 그런 다음 2차 면역 복합체를 일반적으로 세척하여 비특이적으로 결합된 표지된 2차 항체 또는 리간드를 제거하고, 2차 면역 복합체에 남아 있는 표지를 검출한다.
추가 방법은 2단계 접근법에 의한 1차 면역 복합체의 검출을 포함한다. 항체에 대한 결합 친화도를 갖는 항체와 같은 2차 결합 리간드를 상기 기재된 바와 같이 2차 면역 복합체를 형성하는데 사용한다. 세척 후, 2차 면역 복합체를 면역 복합체(3차 면역 복합체)의 형성을 가능하게 하기에 충분한 기간 및 효과적인 조건 하에 다시 2차 항체에 대한 결합 친화도를 갖는 3차 결합 리간드 또는 항체와 접촉시킨다. 3차 리간드 또는 항체를 검출 가능한 표지에 연결하여 이렇게 형성된 3차 면역 복합체를 검출할 수 있다. 이 시스템은 적절한 경우 신호 증폭을 제공할 수 있다.
면역검출의 한 방법은 2개의 상이한 항체를 사용한다. 1차 비오틴화된 항체는 표적 항원을 검출하는데 사용되며, 2차 항체는 복합체화된 비오틴에 부착된 비오틴을 검출하는데 사용된다. 이 방법에서 테스트할 샘플을 먼저 제1 단계 항체를 포함하는 용액에서 인큐베이션한다. 표적 항원이 존재하는 경우, 항체의 일부는 항원에 결합하여 비오틴화된 항체/항원 복합체를 형성한다. 그런 다음 항체/항원 복합체를 스트렙타비딘(또는 아비딘), 비오틴화된 DNA 및/또는 상보적인 비오틴화된 DNA의 연속 용액에서 인큐베이션에 의해 증폭시키고, 각 단계는 항체/항원 복합체에 추가 비오틴 부위를 추가한다. 증폭 단계를 적절한 증폭 수준이 달성될 때까지 반복하며, 이 시점에서 샘플을 비오틴에 대한 제2 단계 항체를 포함하는 용액에서 인큐베이션한다. 이 제2 단계 항체를 예를 들어 발색체 기질을 사용하는 조직효소학에 의해 항체/항원 복합체의 존재를 검출하는데 사용할 수 있는 효소로 표지한다. 적절한 증폭으로 현미경에 의해 관찰 가능한 접합체가 생산될 수 있다.
면역검출의 또 다른 공지된 방법은 면역-PCR(중합효소 연쇄 반응) 방법론을 이용한다. PCR법은 비오틴화 DNA와 함께 인큐베이션할 때까지 Cantor법과 유사하지만, 스트렙타비딘 및 비오틴화된 DNA를 여러 차례 인큐베이션하는 대신 DNA/비오틴/스트렙타비딘/항체 복합체를 항체를 방출하는 낮은 pH 또는 고염 완충액으로 세척한다. 그런 다음 생성된 세척 용액을 사용하여 적절한 대조군이 있는 적절한 프라이머로 PCR 반응을 수행한다. 적어도 이론상으로는 PCR의 고도의 증폭 능력과 특이성을 이용하여 단일 항원 분자를 검출할 수 있다.
A. ELISA
면역분석은 가장 간단하고 직접적인 의미에서 결합 분석이다. 특정 바람직한 면역분석은 당업계에 공지된 다양한 유형의 효소 결합 면역흡착 분석(ELISA) 및 방사선면역분석(RIA)이다. 조직 절편을 사용한 면역조직화학 검출도 특히 유용하다. 그러나, 검출이 이러한 기술에 제한되지 않고 웨스턴 블로팅, 도트 블로팅, FACS 분석 등이 또한 사용될 수 있음을 쉽게 이해할 것이다.
하나의 예시적인 ELISA에서, 본 개시내용의 항체를 폴리스티렌 미세적정 플레이트 내의 웰과 같은 단백질 친화도를 나타내는 선택된 표면 상에 고정시킨다. 그런 다음, SARS-CoV-2 또는 SARS-CoV-2 항원을 포함하는 것으로 예상되는 테스트 조성물을 웰에 첨가한다. 결합 및 비특이적으로 결합된 면역복합체를 제거하기 위한 세척 후 결합된 항원을 검출할 수 있다. 검출 가능한 표지에 연결된 또 다른 항 SARS-CoV-2 항체를 추가하여 검출할 수 있다. 이러한 유형의 ELISA는 간단한 "샌드위치 ELISA"이다. 검출은 또한 2차 항 SARS-CoV-2 항체를 추가한 후, 2차 항체에 대한 결합 친화도를 갖는 3차 항체를 첨가함으로써 달성할 수 있으며, 3차 항체는 검출 가능한 표지에 연결되어 있다.
또 다른 예시적인 ELISA에서, SARS-CoV-2 또는 SARS-CoV-2 항원을 포함하는 것으로 예상되는 샘플을 웰 표면에 고정시킨 다음, 본 개시내용의 항-SARS-CoV-2 항체와 접촉시킨다. 결합 및 비특이적으로 결합된 면역 복합체를 제거하기 위한 세척 후 결합된 항-SARS-CoV-2 항체를 검출한다. 초기 항-SARS-CoV-2 항체가 검출 가능한 표지에 연결된 경우 면역 복합체를 직접 검출할 수 있다. 다시, 면역 복합체는 1차 항 SARS-CoV-2 항체에 대한 결합 친화도를 갖는 2차 항체를 사용하여 검출할 수 있으며, 2차 항체는 검출 가능한 표지에 연결되어 있다.
사용된 형식에 관계없이, ELISA는 코팅, 인큐베이션 및 결합, 비특이적으로 결합된 종을 제거하기 위한 세척, 및 결합된 면역 복합체의 검출과 같은 특정 특징을 공통적으로 갖는다. 아래에 기재되어 있다.
항원 또는 항체로 플레이트를 코팅할 때, 일반적으로 플레이트의 웰을 항원 또는 항체 용액과 함께 밤새 또는 특정 시간 동안 인큐베이션할 것이다. 그런 다음 플레이트의 웰을 세척하여 불완전하게 흡착된 물질을 제거한다. 웰의 나머지 이용 가능한 표면을 그 다음 테스트 항혈청과 관련하여 항원적으로 중성인 비특이적 단백질로 "코팅"한다. 여기에는 소 혈청 알부민(BSA), 카제인 또는 분유 용액이 포함된다. 코팅은 고정 표면의 비특이적 흡착 부위를 차단하여 표면에 대한 항혈청의 비특이적 결합으로 인한 배경을 감소시킨다.
ELISA에서, 직접 절차보다는 2차 또는 3차 검출 수단을 사용하는 것이 아마도 더 통상적일 것이다. 따라서 웰에 단백질 또는 항체를 결합하고 배경을 감소시키기 위해 비반응성 물질로 코팅하고 결합되지 않은 물질을 제거하기 위해 세척한 후 고정 표면을 면역 복합체(항원/항체) 형성을 가능하게 하기에 효과적인 조건에서 테스트 생물학적 샘플과 접촉시킨다. 이어서, 면역 복합체의 검출은 표지된 2차 결합 리간드 또는 항체, 및 표지된 3차 항체 또는 3차 결합 리간드와 함께 2차 결합 리간드 또는 항체가 필요하다.
"면역 복합체(항원/항체) 형성을 가능하게 하기에 효과적인 조건 하"는 조건이 바람직하게는 항원 및/또는 항체를 BSA, 소 감마 글로불린(BGG) 또는 인산염 완충 식염수(PBS)/Tween과 같은 용액으로 희석하는 단계를 포함함을 의미한다. 이러한 추가된 제제는 또한 비특이적 배경의 감소를 돕는 경향이 있다.
"적합한" 조건은 또한 인큐베이션이 효과적인 결합을 가능하게 하기에 충분한 온도 또는 시간 기간 동안 진행됨을 의미한다. 인큐베이션 단계는 일반적으로 약 1 내지 2 내지 4시간 정도, 바람직하게는 25℃ 내지 27℃ 정도의 온도에서 이루어지거나, 약 4℃ 정도에서 밤새 이루어질 수 있다.
ELISA에서 모든 인큐베이션 단계 후에, 접촉된 표면을 세척하여 비-복합체 물질을 제거한다. 바람직한 세척 절차는 PBS/Tween 또는 붕산염 완충액과 같은 용액으로 세척하는 단계를 포함한다. 테스트 샘플과 원래 결합된 물질 사이에 특이적 면역 복합체의 형성 및 후속 세척 후, 극소량의 면역 복합체의 발생을 결정할 수 있다.
검출 수단을 제공하기 위해, 2차 또는 3차 항체는 검출을 가능하게 하는 관련 표지를 가질 것이다. 바람직하게는, 이는 적절한 발색 기질과 함께 인큐베이션할 때 발색을 생성하는 효소일 것이다. 따라서, 예를 들어, 추가 면역 복합체 형성의 발생에 유리한 조건(예를 들어, PBS-Tween과 같은 PBS 포함 용액에서 실온에서 2시간 동안 인큐베이션) 하에서 일정 기간 동안 우레아제, 글루코스 옥시다제, 알칼리성 포스파타제 또는 과산화수소-접합 항체와 1차 및 2차 면역 복합체를 접촉시키거나 인큐베이션하기를 원할 것이다.
표지된 항체와 함께 인큐베이션한 후, 결합되지 않은 물질을 제거하기 위해 세척한 후, 표지의 양을 예를 들어, 효소 표지로서 과산화효소의 경우 H2O2 또는 요소, 또는 브로모크레졸 퍼플, 또는 2,2'-아지노-디-(3-에틸-벤즈티아졸린-6-술폰산(ABTS)과 같은 발색 기질과 함께 인큐베이션함으로써 정량화한다. 그런 다음 관찰 가능한 스펙트럼 분광 광도계를 사용하여 생성된 발색 정도를 측정하여 정량화한다.
또 다른 실시양태에서, 본 개시내용은 경쟁 형식의 사용을 고려한다. 이는 샘플에서 SARS-CoV-2 항체를 검출하는데 특히 유용하다. 경쟁 기반 분석에서 확인되지 않은 양의 분석물 또는 항체를 확인된 양의 표지된 항체 또는 분석물을 대체하는 능력에 의해 결정한다. 따라서 신호의 정량화 가능한 손실은 샘플에서 확인되지 않은 항체 또는 분석물의 양을 나타낸다.
여기에서, 본 발명자는 샘플에서 SARS-CoV-2 항체의 양을 결정하기 위해 표지된 SARS-CoV-2 단일클론 항체의 사용을 제안한다. 기본 형식에는 확인된 양의 SARS-CoV-2 단일클론 항체(검출 가능한 표지에 연결됨)를 SARS-CoV-2 항원 또는 입자와 접촉시키는 단계가 포함된다. SARS-CoV-2 항원 또는 유기체를 바람직하게는 지지체에 부착시킨다. 표지된 단일클론 항체를 지지체에 결합시킨 후, 샘플을 첨가하고 샘플 내의 임의의 표지되지 않은 항체가 표지된 단일클론 항체와 경쟁하여 이를 대체하도록 하는 조건 하에 인큐베이션한다. 손실된 표지 또는 남아 있는 표지를 측정함으로써(그리고 결합된 표지의 원래 양에서 이를 제외함) 표지되지 않은 항체가 지지체에 결합된 양 및 따라서 샘플에 존재하는 항체의 양을 결정할 수 있다.
B. 웨스턴 블롯
웨스턴 블롯(대안적으로 단백질 면역블롯)은 조직 균질액 또는 추출물의 소정의 샘플에서 특정 단백질을 검출하는데 사용되는 분석 기술이다. 이는 겔 전기영동을 사용하여 폴리펩타이드의 길이(변성 조건) 또는 단백질의 3차원 구조(고유/비변성 조건)에 따라 천연 또는 변성된 단백질을 분리한다. 그런 다음 단백질을 막(일반적으로 니트로셀룰로오스 또는 PVDF)으로 옮기고, 여기서 표적 단백질에 특이적인 항체를 사용하여 프로빙(검출)한다.
샘플은 전체 조직 또는 세포 배양물에서 채취할 수 있다. 대부분의 경우, 고형 조직을 먼저 블렌더(더 큰 샘플 부피의 경우)를 사용하거나, 균질화기(더 작은 부피)를 사용하거나 초음파 처리를 사용하여 기계적으로 분해한다. 세포를 또한 위의 기계적 방법 중 하나로 파괴하여 개방시킬 수 있다. 그러나 박테리아, 바이러스 또는 환경 샘플이 단백질의 공급원일 수 있으므로 웨스턴 블로팅은 세포 연구에만 국한되지 않음을 이해해야 한다. 다양한 세정제, 염 및 완충액을 사용하여 세포 용해를 촉진하고 단백질을 가용화할 수 있다. 자체 효소에 의한 샘플의 분해를 방지하기 위해 프로테아제 및 포스파타제 억제제가 종종 추가된다. 조직 제조는 단백질 변성을 방지하기 위해 종종 저온에서 수행된다.
샘플의 단백질을 겔 전기영동을 사용하여 분리한다. 단백질의 분리는 등전점(pI), 분자량, 전하 또는 이러한 요인의 조합에 의해 수행될 수 있다. 분리의 특성은 샘플의 처리와 겔의 특성에 따라 다르다. 이는 단백질을 결정하는 매우 유용한 방법이다. 2차원(2-D) 겔을 사용하여 단일 샘플의 단백질을 2차원으로 확산시킬 수 있다. 단백질은 1차원에서 등전점(순전하가 중성인 pH)에 따라, 2차원에서 분자량에 따라 분리된다.
단백질이 항체 검출에 이용 가능하도록 하기 위해, 단백질을 겔 내에서 니트로셀룰로스 또는 폴리비닐리덴 디플루오라이드(PVDF)로 제조된 막으로 이동시킨다. 막을 겔 위에 놓고 그 위에 여과지 층을 배치한다. 전체 층을 모세관 작용에 의해 여과지 위로 이동하는 완충 용액에 배치하여 단백질을 이동시킨다. 단백질을 옮기는 또 다른 방법은 일렉트로블로팅(electroblotting)이라고 하며 전류를 사용하여 겔에서 PVDF 또는 니트로셀룰로스 막으로 단백질을 유인한다. 단백질은 겔 내에서 조직을 유지하면서 겔 내에서 막으로 이동한다. 이 블로팅 과정의 결과, 단백질은 검출을 위해 얇은 표면층에 노출된다(아래 참조). 두 종류의 막을 비특이적 단백질 결합 특성(즉, 모든 단백질을 균등하게 잘 결합함)으로 선택한다. 단백질 결합은 소수성 상호작용뿐만 아니라 막과 단백질 사이의 하전 상호작용을 기반으로 한다. 니트로셀룰로스 막은 PVDF보다 저렴하지만 훨씬 더 약하고 반복되는 프로빙에 지속되지 못한다. 겔에서 막으로의 단백질 전달의 균일성과 전반적인 효율성을 막을 쿠마시 브릴리언트 블루(Coomassie Brilliant Blue) 또는 Ponceau S 염료로 염색하여 확인할 수 있다. 전달되면, 표지된 1차 항체 또는 표지되지 않은 1차 항체를 사용하여 단백질을 검출한 후 1차 항체의 Fc 영역에 결합하는 표지된 단백질 A 또는 표지된 2차 항체를 사용하여 간접적인 검출을 수행한다.
C. 측방 유동 분석
측방 유동 면역크로마토그래피 분석으로도 알려진 측방 유동 분석은 전문적이고 값비싼 장비가 필요 없지만, 판독 장비에서 지원하는 많은 실험실 기반 응용 프로그램이 있는 샘플(매트릭스)에서 표적 분석물의 존재(또는 부재)를 검출하기 위한 간단한 장치이다. 일반적으로 이러한 테스트는 가정 테스트, 현장 진료 테스트 또는 실험실 사용을 위해 자원이 적은 의료 진단으로 사용된다. 널리 보급되고 잘 알려진 응용 프로그램은 가정 임신 테스트이다.
이 기술은 다공성 종이 조각 또는 소결 중합체와 같은 일련의 모세관 층을 기반으로 한다. 이 요소들 각각은 체액(예를 들어, 소변)을 자발적으로 운반하는 능력을 가지고 있다. 제1 요소(샘플 패드)는 스펀지 역할을 하며 과량의 샘플 유체를 보유한다. 흡수되면 유체는 제2 요소(결합 패드)로 이동하고, 이 요소에는 제조업체가 소위 접합체라고 하는 건조된 형식의 생리 활성 입자(아래 참조)를 표적 분자(예를 들어, 항원)와 입자 표면에 고정된 화학반응 대상(예를 들어, 항체) 간의 최적화된 화학 반응을 가능하게 하기 위한 모든 것을 포함하는 염-당 매트릭스에 저장한다. 샘플 유체가 염-당 매트릭스를 용해하는 동안 입자도 용해하고 하나의 조합된 수송 작용으로 샘플과 접합체가 다공성 구조를 통해 흐르는 동안 혼합된다. 이러한 방식으로 분석 물질은 제3 모세관 층을 통해 더 이동하면서 입자에 결합한다. 이 물질에는 제조업체에서 제3 분자를 고정시킨 하나 이상의 영역(종종 스트립이라고 함)이 있다. 샘플-접합체 혼합물이 이러한 스트립에 도달할 때까지 분석물질은 입자에 결합되고 제3 '포획' 분자는 복합체에 결합된다. 잠시 후 점점 더 많은 유체가 스트립을 통과하면 입자가 축적되고 스트립 영역의 색상이 바뀐다. 일반적으로 적어도 2개의 스트립이 있다: 하나(대조군)는 임의의 입자를 포획하여 반응 조건과 기술이 제대로 작동했음을 보여주는 것이고, 제2 스트립은 특정 포획 분자를 포함하고 분석물 분자가 고정된 입자만 포획한다. 이러한 반응 구역을 통과한 후 유체는 단순히 폐기물 용기 역할을 하는 최종 다공성 물질인 심지로 유입된다. 측방 유동 테스트는 경쟁 또는 샌드위치 분석으로 작동할 수 있다. 측방 유동 분석은 미국 특허 제 6,485,982호에 개시되어 있다.
D. 면역조직화학
본 개시내용의 항체는 또한 면역조직화학(IHC)에 의한 연구를 위해 제조된 생성-동결 및/또는 포르말린-고정, 파라핀-포매 조직 블록 둘 모두와 함께 사용될 수 있다. 이러한 미립자 표본으로부터 조직 블록을 제조하는 방법은 다양한 예후 인자에 대한 이전의 IHC 연구에서 성공적으로 사용되었으며 당업자에게 잘 알려져 있다(문헌[Brown et al., 1990; Abbondanzo et al., 1990; Allred et al., 1990]).
간단히 말해서, 동결 절편을 작은 플라스틱 캡슐의 인산염 완충 식염수(PBS)에서 실온에서 동결된 "분쇄된" 조직 50 ng을 재수화하고; 원심분리에 의해 입자를 펠렛화하고; 점성 포매 매질(OCT)에 이를 재현탁하고; 캡슐을 뒤집고/거나 원심분리에 의해 다시 펠렛화하고; -70℃ 이소펜탄에서 급속 동결하고; 플라스틱 캡슐을 절단하고/거나 조직의 냉동 실린더를 제거하고; 저온유지장치 마이크로톰 척에 조직 실린더를 고정하고/거나; 캡슐에서 25 내지 50개의 연속 절편을 절단하여 제조할 수 있다. 대안적으로 전체 동결 조직 샘플을 연속 절편 절단에 사용할 수 있다.
영구 절편을 플라스틱 마이크로퓨지 튜브에서 50 mg 샘플의 재수화; 펠렛화; 4시간 고정 동안 10% 포르말린에 재현탁; 세척/펠렛화; 가온된 2.5% 한천에 재현탁; 펠렛화; 한천을 단단하게 하기 위해 얼음물에서 냉각; 튜브로부터 조직/한천 블록 제거; 파라핀에서의 블록 침투 및/또는 포매; 및/또는 최대 50개의 연속 영구 절편 절단를 포함하는 유사한 방법으로 제조할 수 있다. 다시, 전체 조직 샘플을 대체할 수 있다.
E. 면역검출 키트
또 다른 실시양태에서, 본 개시내용은 상기 기재된 면역검출 방법과 함께 사용하기 위한 면역검출 키트에 관한 것이다. 항체는 SARS-CoV-2 또는 SARS-CoV-2 항원을 검출하는데 사용될 수 있으므로 항체가 키트에 포함될 수 있다. 따라서 면역검출 키트는 적절한 용기 수단에 SARS-CoV-2 또는 SARS-CoV-2 항원에 결합하는 1차 항체, 및 선택적으로 면역검출 시약을 포함할 것이다.
특정 실시양태에서, SARS-CoV-2 항체를 컬럼 매트릭스 및/또는 미세역가 플레이트의 웰과 같은 고체 지지체에 미리 결합시킬 수 있다. 키트의 면역검출 시약은 소정의 항체와 결합되거나 연결된 검출가능한 표지를 포함하여 다양한 형태 중 임의의 하나를 취할 수 있다. 2차 결합 리간드와 결합되거나 부착된 검출가능한 표지가 또한 고려된다. 예시적인 2차 리간드는 1차 항체에 대한 결합 친화도를 갖는 2차 항체이다.
본 키트에 사용하기 위한 추가의 적합한 면역검출 시약은 2차 항체에 대한 결합 친화도를 갖는 3차 항체와 함께 1차 항체에 대한 결합 친화도를 갖는 2차 항체를 포함하는 이성분 시약을 포함하고, 3차 항체는 검출 가능한 표지에 연결되어 있다. 상기 언급된 바와 같이, 다수의 예시적인 표지가 당업계에 공지되어 있고 이러한 모든 표지가 본 개시내용과 관련하여 사용될 수 있다.
키트는 표지에 관계없이 SARS-CoV-2 또는 SARS-CoV-2 항원의 적절하게 분취된 조성물을 추가로 포함할 수 있으며, 이는 검출 분석을 위한 표준 곡선을 작도하는데 사용할 수 있다. 키트는 항체-표지 접합체를 완전히 접합된 형태로, 중간체 형태로, 또는 키트 사용자가 접합할 별도의 모이어티로 포함할 수 있다. 키트의 성분은 수성 매질 또는 동결건조된 형태로 포장될 수 있다.
키트의 용기 수단은 일반적으로 적어도 하나의 바이알, 시험관, 플라스크, 병, 주사기 또는 기타 용기 수단을 포함할 것이며, 그 안에 항체가 배치될 수 있거나 바람직하게는 적절하게 분취될 수 있다. 본 개시내용의 키트는 또한 통상적으로 상업적 판매를 위해 밀폐된 구획에 항체, 항원, 및 임의의 다른 시약 용기를 포함하기 위한 수단을 포함할 것이다. 이러한 용기는 적절한 바이알이 유지되는 사출 또는 취입 성형 플라스틱 용기를 포함할 수 있다.
F. 백신 및 항원 특질 제어 분석
본 개시내용은 또한 샘플에서 바이러스 항원의 항원 완전성을 평가하는데 사용하기 위한 본 명세서에 기재된 바와 같은 항체 및 항체 단편의 사용을 고려한다. 백신과 같은 생물학적 의약품은 일반적으로 분자적으로 특성화될 수 없다는 점에서 화학 의약품과 다르고; 항체는 유의하게 복합체화된 큰 분자이며 제조시마다 광범위하게 변할 수 있는 기능을 가지고 있다. 이는 또한 인생의 출발 시점에 있는 소아를 포함하여 건강한 개체에게 투여되므로 가능한 한 그 자체로 유해함을 유발함이 없이, 최대한 생명을 위협하는 질병을 예방하거나 치료하는데 효과적임을 보장하기 위해 이의 특질이 중요하게 강조되어야 한다.
백신의 생산 및 유통의 증가하는 세계화는 공중 보건 문제를 더 잘 관리할 수 있는 새로운 가능성을 열었지만 다양한 공급원에 걸쳐 조달된 백신의 균등성 및 호환성에 대한 의문이 제기되었다. 출발 물질, 생산 및 특질 제어 테스트의 국제 표준화, 이러한 산물의 제조 및 사용 방식에 대한 규제 감독에 대한 높은 기대치 설정은 따라서 지속적인 성공을 위한 초석이 되었다. 그러나 이 분야는 끊임없이 변화하는 분야로 남아 있으며 이 분야의 지속적인 기술 발전은 가장 오래된 공중 보건 위협은 물론 새로운 위협(말라리아, 유행성 인플루엔자, HIV 등)에 대한 강력한 새 무기 개발을 약속하지만, 또한 산물이 달성 가능한 최고 특질 기준을 계속 충족하도록 제조업체, 규제 당국 및 광범위한 의료계에 큰 압력을 가한다.
따라서, 항원 또는 백신은 제조 과정 중 임의의 시점 또는 임의의 공급원으로부터 얻을 수 있다. 따라서 특질 제어 과정은 바이러스 항원에 대한 본 명세서에 개시된 항체 또는 단편의 결합을 확인하는 면역분석을 위한 샘플을 제조하는 것으로 개시할 수 있다. 이러한 면역분석은 본 명세서의 다른 곳에서 개시되며, 이들 중 임의의 것을 항원의 구조적/항원 완전성을 평가하는데 사용할 수 있다. 항원적으로 정확하고 온전한 항원의 허용 가능한 양을 포함하는 샘플을 찾기 위한 표준은 규제 기관에서 설정할 수 있다.
항원 완전성(antigen integrity)이 평가되는 또 다른 중요한 실시양태는 저장 수명 및 저장 안정성을 결정하는 것이다. 백신을 포함한 대부분의 의약품은 시간이 지나면서 특질이 저하될 수 있다. 따라서, 시간이 지남에 따라 백신과 같은 항원이 분해되거나 불안정화되어 더 이상 항원이 아니고/거나, 대상체에게 투여될 때 면역 반응을 생성할 수 있는지를 결정하는 것이 중요하다. 다시 말하지만, 항원으로서 온전한 항원의 허용 가능한 양을 포함하는 샘플을 찾기 위한 표준은 규제 기관에서 설정할 수 있다.
특정 실시양태에서, 바이러스 항원은 하나 이상의 보호 에피토프를 포함할 수 있다. 이러한 경우, 2, 3, 4, 5개 이상의 항체와 같은 하나 초과의 항체의 결합을 조사하는 분석을 사용하는 것이 유용할 수 있다. 이러한 항체는 밀접하게 관련되어, 서로 인접하거나 심지어 중첩된 에피토프에 결합한다. 다른 한편, 이는 항원의 별개의 부분과는 별개의 에피토프를 나타낼 수 있다. 다수의 에피토프의 온전성을 검사하여 항원의 전체 온전성에 대한 보다 완전한 형태와 보호 면역 반응을 생성하는 기능을 결정할 수 있다.
본 개시내용에 기재된 바와 같은 항체 및 이의 단편은 또한 보호성 SARS-CoV-2 항체의 존재를 검출함으로써 백신접종 절차의 효능을 모니터링하기 위해 키트에서 사용될 수 있다. 본 개시내용에 기재된 바와 같은 항체, 항체 단편, 또는 이의 변이체 및 유도체는 또한 적절한 면역원성을 갖는 백신 제조를 모니터링하기 위해 키트에 사용될 수 있다.
[표 1]
항체 가변 영역에 대한 뉴클레오타이드 서열
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[표 2]
항체 가변 영역에 대한 단백질 서열
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[표 3]
중쇄 서열
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[표 4]
경쇄 서열
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*****************
본 명세서에 개시되고 청구된 모든 조성물 및 방법은 본 개시내용에 비추어 과도한 실험 없이 제조 및 실행될 수 있다. 본 개시내용의 조성물 및 방법이 바람직한 실시양태와 관련하여 기재되었지만, 본 개시내용의 개념, 사상 및 범위를 벗어나지 않으면서 본 명세서에 개시된 방법의 조성물 및 방법 및 단계 또는 단계의 순서에 변형이 적용될 수 있음이 당업자에게 명백할 것이다. 보다 구체적으로, 화학적 및 생리학적으로 모두 관련된 특정 제제가 동일하거나 유사한 결과가 달성되는 동안 본 명세서에 기재된 제제를 대체할 수 있음이 명백할 것이다. 당업자에게 자명한 이러한 모든 유사한 대체물 및 변형은 첨부된 청구범위에 의해 정의된 본 개시내용의 사상, 범위 및 개념 내에 있는 것으로 고려된다.
VII. 참조
예시적인 절차 또는 본 명세서에 기재된 것에 보충적인 기타 세부사항을 제공하는 한, 다음 참조문헌은 본 명세서에 참조로 명시적으로 포함된다.
미국 특허 제 3,817,837호
미국 특허 제 3,850,752호
미국 특허 제 3,939,350호
미국 특허 제 3,996,345호
미국 특허 제 4,196,265호
미국 특허 제 4,275,149호
미국 특허 제 4,277,437호
미국 특허 제 4,366,241호
미국 특허 제 4,472,509호
미국 특허 제 4,554,101호
미국 특허 제 4,680,338호
미국 특허 제 4,816,567호
미국 특허 제 4,867,973호
미국 특허 제 4,938,948호
미국 특허 제 5,021,236호
미국 특허 제 5,141,648호
미국 특허 제 5,196,066호
미국 특허 제 5,563,250호
미국 특허 제 5,565,332호
미국 특허 제 5,856,456호
미국 특허 제 5,880,270호
미국 특허 제 6,485,982호
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SEQUENCE LISTING <110> VANDERBILT UNIVERSITY <120> HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-CoV- 2) <130> VBLT.P0307WO1 <150> US 62/972,877 <151> 2020-02-11 <150> US 62/994,627 <151> 2020-03-25 <160> 9901 <170> PatentIn version 3.5 <210> 1 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1 Cys Ser Tyr Ala Gly Ser Ser Thr Val Val Phe 1 5 10 <210> 2 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2 ttctatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 3 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3 Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 4 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4 ttcaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 5 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5 Phe Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 6 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6 tgtaatcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 7 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7 Cys Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 8 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8 tcttatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctcttggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 9 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 10 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 10 tctcatcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtagta 120 ttcggcgga 129 <210> 11 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 11 Ser His Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 12 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 12 tctcatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgagtctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 13 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 13 Ser His Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 14 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 14 tctactcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgtgctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag caccgtggta 120 ttcggcgga 129 <210> 15 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 15 Ser Thr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 16 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 16 tctaatcggt tctctggctc caagtctggc aacacgggct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 17 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 17 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Gly Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 18 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 18 tctaatcgct tctcttgctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgatg acgaggctga ttattactgc tgctcatatg caggtagtag caccgtggta 120 ttcggcgga 129 <210> 19 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 19 Ser Asn Arg Phe Ser Cys Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 20 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 20 tctaatcgct tctcttgctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgatgctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 21 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 21 Ser Asn Arg Phe Ser Cys Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Asp Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 22 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 22 tctaatcgct tctctgtctc caagtctggc aacacggcct cccttacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 23 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 23 Ser Asn Arg Phe Ser Val Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 24 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 24 tctaatcgct tctctggctc gatgtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 25 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 25 Ser Asn Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 26 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 26 tctaatcgct tctctggctc catgtctggc aacacggcct ccctgacatt ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 27 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 27 Ser Asn Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 28 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 28 tctaatcgct tctctggctc catgtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgagtctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 29 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 29 Ser Asn Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 30 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 30 tctaatcgct tctctggctc catgtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgttgta 120 ttcggcgga 129 <210> 31 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 31 tctaatcgct tctctggctc caagtctggc tactcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag caccgtggta 120 ttcggcgga 129 <210> 32 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 32 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 33 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 33 tctaatcgct tctctggctc caagtctggc tacacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 34 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 34 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 35 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 35 tctaatcgct tctctggctc caagtctggc tacacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag caccgtggta 120 ttcggcgga 129 <210> 36 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 36 tctaatcgct tctctggctc caagtctggc atcacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 37 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 37 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 38 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 38 tctaatcgct tctctggctc caagtctggc atcacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtagta 120 ttcggcgga 129 <210> 39 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 39 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgacaat ctctgggctc 60 caggctgatg acgaggctga ttattactgc tgctcatatg caggtagtag caccgtggta 120 ttcggcgga 129 <210> 40 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 40 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 41 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 41 tctaatcgct tctctggctc caagtctggc aacactgcct ccctgacaat ctcttggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtagta 120 ttcggcgga 129 <210> 42 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 42 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 43 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 43 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcggt 129 <210> 44 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 44 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 45 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 45 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag caccgtggtt 120 ttcggcgga 129 <210> 46 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 46 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 47 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 47 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacgat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcgtatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 48 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 48 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 cagtctgagg acgagtctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 49 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 49 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 50 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 50 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 51 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 51 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtagta 120 ttcggcgga 129 <210> 52 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 52 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag caccgtggta 120 ttcggcgga 129 <210> 53 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 53 tctaatcgct tctctgactc caagtctggc aacacggcct ccctggcaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag caccgtggta 120 ttcggcgga 129 <210> 54 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 54 Ser Asn Arg Phe Ser Asp Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 55 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 55 gtaattcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 56 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 56 Val Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 57 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 57 cttatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 58 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 58 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 59 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 59 cttatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag caccgtggta 120 ttcggcgga 129 <210> 60 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 60 ctaattcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 61 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 61 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg cgggtagtag cactgtggta 120 tttggcgga 129 <210> 62 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 62 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 63 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 63 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtagta 120 ttcggcgga 129 <210> 64 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 64 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag caccgtggta 120 ttcggcgga 129 <210> 65 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 65 ctaatacgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 66 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 66 cctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acggggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 67 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 67 Pro Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Gly Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 68 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 68 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgagactga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 69 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 69 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Thr Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 70 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 70 gctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggta 120 ttcggcgga 129 <210> 71 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 71 Ala Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 72 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 72 tcttatcgct tctctggctc caagtctggc aacacggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg cgggtagtag cactgtggta 120 tttggcgga 129 <210> 73 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 73 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 74 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 74 tctattcgct tctctggctc caagtctggc aagacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg cgggtagtag cactgtggta 120 tttggcgga 129 <210> 75 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 75 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 76 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 76 tctaatcgct tctctggctc cttgtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg cgggtagtag cactgtggta 120 tttggcgga 129 <210> 77 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 77 Ser Asn Arg Phe Ser Gly Ser Leu Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 78 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 78 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg cgggtagtag cactgtggta 120 tttggcgga 129 <210> 79 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 79 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 80 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 80 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg cgggtagtag cactgtggta 120 tttggcgga 129 <210> 81 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 81 tctaatcgct tctctggctc caagtctggc aacacggcct ccccgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactac tgctcatatg cgggtagtag cactgtggta 120 tttggcgga 129 <210> 82 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 82 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Pro Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Tyr Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 83 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 83 Cys Ser Tyr Ala Gly Ser Ser Thr Leu Val Phe 1 5 10 <210> 84 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 84 ttctatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 85 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 85 Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 86 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 86 tgtaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgtgctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 87 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 87 Cys Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 88 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 88 tgtaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgtgctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagta 120 ttcggcgga 129 <210> 89 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 89 tcttttcgct tctctggctc caagtctggc aactcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 90 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 90 Ser Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 91 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 91 tcttatcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 92 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 92 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 93 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 93 tctattcgct tctctggctc caagtctggc atcacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 94 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 94 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 95 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 95 tctattcgct tctctggctc caagtctggc aactcggcct ccctgacaat ctctgggctc 60 cagtctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 96 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 96 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 97 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 97 tctactcgct tctctggctc caagtcttgc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 98 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 98 Ser Thr Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 99 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 99 tctactcgct tctctggctc caagtctggc aactcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 100 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 100 Ser Thr Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 101 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 101 tctaatcgct tgtctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggatga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 102 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 102 Ser Asn Arg Leu Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Asp Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 103 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 103 tctaatcgct tctctgtctc caagtctggc aacacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 104 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 104 Ser Asn Arg Phe Ser Val Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 105 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 105 tctaatcgct tctctggctc gaagtctggc aacacggcct ccctgacaat ctctgggctc 60 cagtctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 106 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 106 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 107 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 107 tctaatcgct tctctggctc gaagtctggc aacacggact ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 108 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 108 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Asp Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 109 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 109 tctaatcgct tctctggctc caggtctggc agcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 110 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 110 Ser Asn Arg Phe Ser Gly Ser Arg Ser Gly Ser Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 111 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 111 tctaatcgct tctctggctc caagtctggc tacacggcct ccctgacaat ctcttggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 112 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 112 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 113 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 113 tctaatcgct tctctggctc caagtctggc atctcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 114 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 114 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 115 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 115 tctaatcgct tctctggctc caagtctggc atcacggcct ccctgactat ctcttggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagta 120 ttcggcgga 129 <210> 116 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 116 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 117 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 117 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 118 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 118 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 119 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 119 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagta 120 ttcggcgga 129 <210> 120 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 120 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 121 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 121 tctaatcgct tctctggctc caagtctggc aacagggcct ccctgacatt ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 122 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 122 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Arg Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 123 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 123 tctaatcgct tctctggctc caagtctggc aacacggcgt acctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 124 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 124 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Tyr Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 125 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 125 tctaatcgct tctctggctc caagtctggc aacacggcct cgctgacaat ctctggtctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 126 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 126 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 127 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 127 tctaatcgct tctctggctc caagtctggc aacacggcct cgctgacaat ctctgggctg 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 128 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 128 tctaatcgct tctctggctc caagtctggc aacacggcct cccttacaat ctctgtgctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 129 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 129 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 130 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 130 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctcttggctc 60 cagtctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 131 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 131 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 132 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 132 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 133 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 133 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagta 120 ttcggcgga 129 <210> 134 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 134 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactctggta 120 ttcggcgga 129 <210> 135 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 135 tctaatcgct tctctggctc caagtctggc aacacggccg ccctgacact ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 136 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 136 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ala Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 137 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 137 tctaatcgca tctctggctc caagtcaggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 138 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 138 Ser Asn Arg Ile Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 139 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 139 tcaattcgct tctctggctc caagtctggc aacacggcct ccccgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 140 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 140 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Pro Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 141 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 141 gtaattcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 142 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 142 Val Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 143 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 143 gctaatcgct gctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 144 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 144 Ala Asn Arg Cys Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 145 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 145 cttattcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 146 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 146 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 147 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 147 cttatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 148 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 148 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggta 120 ttcggcgga 129 <210> 149 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 149 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagta 120 ttcggcgga 129 <210> 150 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 150 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactctggta 120 ttcggcgga 129 <210> 151 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 151 tttctaatcg cttctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagta 120 ttcggcgga 129 <210> 152 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 152 Phe Leu Ile Ala Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 153 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 153 Cys Ser Tyr Ala Gly Ser Ser Thr Tyr Val Phe 1 5 10 <210> 154 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 154 ttctatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 155 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 155 Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 156 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 156 tctcatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctggtgtc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 157 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 157 Ser His Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Val Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 158 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 158 tctattcgct tctctggctt caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattacagc tgctcatatg caggtagtag cacttatgtc 120 ttcagaact 129 <210> 159 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 159 Ser Ile Arg Phe Ser Gly Phe Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Ser Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Arg Thr 35 40 <210> 160 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 160 tctattcgct tctctggctc gaagtctggc aagacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 161 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 161 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 162 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 162 tctattcgct tctctggctc ctggtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 163 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 163 Ser Ile Arg Phe Ser Gly Ser Trp Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 164 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 164 tctattcgct tctctggctc catgtctggc aacacggcct ccctgacaat ctcttggctc 60 caggctgagg acgagtctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 165 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 165 Ser Ile Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 166 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 166 tctattcgct tctctggctc caagtctggc atcacggcat ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 167 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 167 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 168 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 168 tctattcgct tctctggctc caagtctggc aacacggcct ccctgtcaat ctctgggctc 60 ctggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 169 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 169 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 170 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 170 tctaatcgct tctctggctg caagtctggc atcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 171 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 171 Ser Asn Arg Phe Ser Gly Cys Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 172 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 172 tctaatcgct tctctggctc caagtcttgc atcacggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 173 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 173 Ser Asn Arg Phe Ser Gly Ser Lys Ser Cys Ile Thr Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 174 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 174 tctaatcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggtact 129 <210> 175 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 175 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 176 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 176 tctaatcgct tctctggctc caagtctggc aagtcggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 177 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 177 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Ser Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 178 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 178 tctaatcgct tctctggctc caagtctggc aactcgggct ccctgacaat ctctgggctc 60 caggctgagg acgagtctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 179 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 179 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Gly Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 180 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 180 tctaatcgct tctctggctc caagtctggc aacagggcct gcctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 181 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 181 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Arg Ala Cys Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 182 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 182 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacact ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 183 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 183 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 184 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 184 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctggtctc 60 caggctgagg acgagtctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 185 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 185 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 186 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 186 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctggggtc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 187 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 187 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Val Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 188 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 188 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 ccggctgagg acgcggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 189 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 189 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Pro Ala Glu Asp Ala Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 190 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 190 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgatg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggatct 129 <210> 191 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 191 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Ser 35 40 <210> 192 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 192 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgagtctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 193 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 193 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 194 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 194 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 195 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 195 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctggcctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag tacttatgtc 120 ttcggaact 129 <210> 196 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 196 tctaatcgct tctctggctc caagtctggc aacacggcat ccctgacaat ctctgggctc 60 cagtctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 197 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 197 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 198 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 198 tctaatcgct tctctggctc caagtctggc aacaaggcct ccctgacaat ctctgggctc 60 cagtctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 199 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 199 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Lys Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 200 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 200 gtaatacgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 201 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 201 Val Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 202 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 202 gcaattcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 203 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 203 Ala Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 204 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 204 cttattcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 205 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 205 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 206 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 206 cttatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 207 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 207 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgagtctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 208 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 208 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Val Phe Gly Thr 35 40 <210> 209 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 209 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 210 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 210 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctggcctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag tacttatgtc 120 ttcggaact 129 <210> 211 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 211 ctaatacgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 212 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 212 tctaatcgct tctctggctc caagtctggg aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttatgtc 120 ttcggaact 129 <210> 213 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 213 Cys Ser Tyr Ala Gly Ser Tyr Thr Tyr Val Phe 1 5 10 <210> 214 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 214 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgacctt ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagtta cacttatgtc 120 ttcggaact 129 <210> 215 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 215 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 216 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 216 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 217 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 217 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 218 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 218 ctgatacgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 219 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 219 cgtgatcgct tctctggctc caagtctggc aacacggcct ccctgtccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 220 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 220 Arg Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 221 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 221 cgtgatcgct tctctggctc caagtctggc aacacggcct ccctgagcat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 222 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 222 cctgatggct tctctggctc caagtctggc aagacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 223 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 223 Pro Asp Gly Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 224 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 224 cctgatcggt tctctggctc caagtctggc atctcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 225 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 225 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 226 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 226 cctgatcgct tctctggctc gaagtctggc atctcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 227 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 227 cctgatcgct tctctggctc gaagtctggc aactcggcct ccctgacctt ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagtta cacttatgtc 120 ttcggaact 129 <210> 228 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 228 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 229 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 229 cctgatcgct tctctggctc gaagtctggc aacacggcct ccctgacctt ctctgggctc 60 caggctgagg atgagtctga ttattactgc tgctcatatg caggcagtta cacttatgtc 120 ttcggaact 129 <210> 230 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 230 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 231 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 231 cctgatcgct tctctggctc catgtctggc aacacggcct ccctgaccat ctctgggctc 60 ctggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 232 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 232 Pro Asp Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 233 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 233 cctgatcgct tctctggctc catgtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggatga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 234 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 234 Pro Asp Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Asp Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 235 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 235 cctgatcgct tctctggctc caagtcttgc aacacggcct ccctgaccat ctctgggctc 60 caggctgatg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 236 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 236 Pro Asp Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 237 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 237 cctgatcgct tctctggctc caagtctggc tacacggcct ccctgacctt ctcttggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagtta cacttatgtc 120 ttcggaact 129 <210> 238 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 238 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Phe Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 239 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 239 cctgatcgct tctctggctc caagtctggc atcacggcct ccctgacgat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttacgtc 120 ttcggaact 129 <210> 240 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 240 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 241 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 241 cctgatcgct tctctggctc caagtctggc aactcggcct ccctgagcat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 242 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 242 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 243 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 243 cctgatcgct tctctggctc caagtctggc aacacgtcct ccctgaccat ctctgggctc 60 gaggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 244 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 244 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ser Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 245 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 245 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgacctt ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagtta cacttatgtc 120 ttcggaact 129 <210> 246 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 246 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 247 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 247 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 gaggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggatct 129 <210> 248 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 248 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Ser 35 40 <210> 249 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 249 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagt atgaggctga ttattactcc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 250 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 250 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Tyr Glu Ala Asp Tyr Tyr Ser Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 251 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 251 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 252 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 252 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 253 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 253 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttacgtc 120 ttcggaact 129 <210> 254 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 254 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttactactgc tgctcatatg caggcagcta cacttatgtt 120 ttcggaact 129 <210> 255 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 255 cctgatcgct tctctggctc caagtcaggc aacacggccg ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 256 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 256 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ala Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 257 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 257 cctgatcgct tctctggctc caagcctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttacgtc 120 ttcggaacc 129 <210> 258 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 258 Pro Asp Arg Phe Ser Gly Ser Lys Pro Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 259 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 259 cctgatcgct tatctggctc caagtctgtc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 260 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 260 Pro Asp Arg Leu Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 261 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 261 cctgatcgct cctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctgg ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 262 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 262 Pro Asp Arg Ser Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Gly Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 263 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 263 cctgatcgct cctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcgtatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 264 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 264 Pro Asp Arg Ser Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 265 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 265 ccgcttcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 266 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 266 Pro Leu Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 267 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 267 actgatcgct tctctggctc caagtcttgc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 268 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 268 Thr Asp Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 269 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 269 actgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggtact 129 <210> 270 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 270 Thr Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 271 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 271 cctgatcgct tctctggctc caagtctggc aacactgcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 272 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 272 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgacgat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttatgtc 120 ttcggaact 129 <210> 273 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 273 Cys Ser Tyr Ala Gly Ser Tyr Thr Trp Val Phe 1 5 10 <210> 274 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 274 gctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctcttggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 275 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 275 Ala Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 276 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 276 ctgttccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagtta cacttgggtg 120 ttcggcgga 129 <210> 277 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 277 Leu Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 278 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 278 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagtta cacttgggtg 120 ttcggcgga 129 <210> 279 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 279 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 280 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 280 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 281 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 281 ccttatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttactactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 282 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 282 Pro Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 283 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 283 ccttatcgct tctctggctc caagtctggc aacacggccc ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttactacggc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 284 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 284 Pro Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Pro Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Gly Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 285 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 285 ccttatcgct tctctggctc caagcctggc aacacggcct ccctgaccgt ctctgggctc 60 caggctgagg atgaggctga ttactactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 286 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 286 Pro Tyr Arg Phe Ser Gly Ser Lys Pro Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Val Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 287 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 287 cctgttcgct tctctggctc gaagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 288 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 288 Pro Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 289 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 289 cctgttcgct tctctggctc caagtctggc aacacggcct ccctgtccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggta 120 ttcggcgga 129 <210> 290 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 290 Pro Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 291 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 291 cctgatcgct tctctggctc gaagtctggc aactcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggta 120 ttcggcgga 129 <210> 292 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 292 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 293 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 293 cctgatcgct tctctggctc caagtctggc tactcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 294 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 294 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 295 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 295 cctgatcgct tctctggctc caagtctggc atctcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagtta cacttgggtg 120 ttcggcgga 129 <210> 296 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 296 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 297 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 297 cctgatcgct tctctggctc caagtctggc aactcggcct cgctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 298 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 298 cctgatcgct tctctggctc caagtctggc aactcggcct ccctgtccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 299 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 299 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 300 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 300 cctgatcgct tctctggctc caagtctggc aactcggcct ccctggccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 301 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 301 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Ala 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 302 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 302 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgtcgat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 303 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 303 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 304 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 304 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctcttggctc 60 caggctgagg atgaggtcga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 305 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 305 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ala Glu Asp Glu Val Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 306 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 306 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagt gtgaggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 307 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 307 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Cys Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 308 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 308 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atggggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 tttggcgga 129 <210> 309 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 309 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Gly Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 310 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 310 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgt tgctcatatg caggcagcta cacttgggta 120 ttcggcgga 129 <210> 311 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 311 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 312 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 312 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagtta cacttgggtg 120 ttcggcgga 129 <210> 313 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 313 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 314 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 314 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgaa 129 <210> 315 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 315 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Glu 35 40 <210> 316 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 316 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggta 120 ttcggcgga 129 <210> 317 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 317 cctgatcgct tctctggctc caactcaggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagtta cacttgggtg 120 ttcggcgga 129 <210> 318 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 318 Pro Asp Arg Phe Ser Gly Ser Asn Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 319 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 319 ccggttcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttgggtg 120 ttcggcgga 129 <210> 320 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 320 ccttatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttactactgc tgctcatatg caggcagcta cacctgggtg 120 ttcggcgga 129 <210> 321 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 321 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Val Val Phe 1 5 10 <210> 322 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 322 aatcgcttct ctgtctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggtt 120 ttcggcgga 129 <210> 323 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 323 Asn Arg Phe Ser Val Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 324 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 324 aatcgcttct ctggctcgaa gtctggcaac agggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 325 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 325 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Arg Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 326 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 326 aatcgcttct ctggctccat gtctggctac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 327 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 327 Asn Arg Phe Ser Gly Ser Met Ser Gly Tyr Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 328 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 328 aatcgcttct ctggctccat gtctggcatc acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgttgta 120 ttcggcgga 129 <210> 329 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 329 Asn Arg Phe Ser Gly Ser Met Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 330 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 330 aatcgcttct ctggctccat gtctggcaac acggcctccc tgacaatctc ttggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 331 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 331 Asn Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 332 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 332 aatcgcttct ctggctccaa gtctggcaac actgcctccc tgacaatctc ttggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 333 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 333 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 334 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 334 aatcgcttct ctggctccaa gtctggcaac acggtctccc tgacaatctc taggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgttgta 120 ttcggcgga 129 <210> 335 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 335 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Val Ser Leu Thr Ile 1 5 10 15 Ser Arg Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 336 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 336 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgtcaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggtt 120 ttcggcgga 129 <210> 337 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 337 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 338 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 338 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgactatctc tgggctccag 60 gctgtggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 339 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 339 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Val Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 340 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 340 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacattctc tgggctgcag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 341 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 341 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Phe 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 342 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 342 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttgccgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 343 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 343 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Cys Arg Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 344 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 344 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttttgtggta 120 ttcggcgga 129 <210> 345 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 345 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 346 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 346 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgttgta 120 ttcggcgga 129 <210> 347 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 347 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 348 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 348 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc taggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtcgta 120 ttcggcgga 129 <210> 349 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 349 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Arg Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 350 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 350 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc atggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 351 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 351 aatcgcttct ctggctccaa gtctggcaac acggcctcac tgacaatctc ttggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 352 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 352 aatcgcttct ctggctccaa gtctggcaac acggcccccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttaccgctgc tcatatgcag gtagtagcac tttcgttgta 120 ttcggcgga 129 <210> 353 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 353 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Pro Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Arg Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 354 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 354 aatcgcttct ctggctccaa gtctggaaac actgcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 355 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 355 aatcgcttct ctgactccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcggc 129 <210> 356 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 356 Asn Arg Phe Ser Asp Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 357 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 357 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttttgtggta 120 ttcggcgga 129 <210> 358 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 358 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Val Phe Gly Gly 35 40 <210> 359 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 359 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgttgta 120 ttcggcgga 129 <210> 360 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 360 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 361 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 361 atacgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtggta 120 ttcggcgga 129 <210> 362 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 362 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Val Phe 1 5 10 <210> 363 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 363 ttctatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 364 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 364 Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 365 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 365 tcttatcgct tctctggctc catgtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 366 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 366 Ser Tyr Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 367 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 367 tctattcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctcttggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 368 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 368 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 369 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 369 tctaatcgct tctctggctg caagtctggc aacacggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 370 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 370 Ser Asn Arg Phe Ser Gly Cys Lys Ser Gly Asn Thr Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 371 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 371 tctaatcgct tctctggctc caagtcttgc aacacggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 372 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 372 Ser Asn Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 373 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 373 tctaatcgct tctctggctc caagtctggc gacacggcct ccctgacaat ctctggactc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 374 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 374 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asp Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 375 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 375 tctaatcgct tctctggctc caagtctggc aagactgcct ccctgacaat ctcttggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 376 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 376 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 377 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 377 tctaatcgct tctctggctc caagtctggc aagacggcct cgctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 378 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 378 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 379 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 379 tctaatcgct tctctggctc caagtctggc aagacggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 380 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 380 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 381 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 381 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 382 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 382 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 383 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 383 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgtcaat ctctgggctc 60 ctggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 384 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 384 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 385 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 385 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacttt ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 386 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 386 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 387 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 387 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 cagtctgagg acgatgctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 388 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 388 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Asp Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 389 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 389 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 390 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 390 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 391 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 391 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagcag caccttcgta 120 ttcggcggc 129 <210> 392 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 392 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ccctgggctc 60 caggctgagg acggggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 393 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 393 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Pro Gly Leu Gln Ala Glu Asp Gly Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 394 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 394 tctaatcgct tctctggctc caagtctggc aacacggccc ccctgacaat ctctgggctc 60 caggctgagg acgaggccga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 395 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 395 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Pro Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 396 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 396 cttatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 397 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 397 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Gly 35 40 <210> 398 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 398 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 399 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 399 ctaatacgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgta 120 ttcggcgga 129 <210> 400 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 400 Cys Ser Tyr Ala Gly Ser Ser Thr Tyr Val Val Phe 1 5 10 <210> 401 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 401 attcgcttct ctggctccaa gtctggcaac acggcctccc tgtcaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttatgtggta 120 ttcggcgga 129 <210> 402 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 402 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Val Val Phe Gly Gly 35 40 <210> 403 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 403 aatcgcttct ctggctccat gtctggcaag acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttatgtggta 120 ttcggcgga 129 <210> 404 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 404 Asn Arg Phe Ser Gly Ser Met Ser Gly Lys Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Val Val Phe Gly Gly 35 40 <210> 405 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 405 aatcgcttct ctggctccaa gtctggctac acggcctccc tgtcaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttatgtggta 120 ttcggcgga 129 <210> 406 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 406 Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Val Val Phe Gly Gly 35 40 <210> 407 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 407 aatcgcttct ctggctccaa gtctggcatc acggcctccc tgtcaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttatgtggta 120 ttcggcgga 129 <210> 408 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 408 Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Val Val Phe Gly Gly 35 40 <210> 409 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 409 aatcgcttct ctggctccaa gtctggcaac tcggcctccc tgactatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttatgtggta 120 ttcggcgga 129 <210> 410 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 410 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Val Val Phe Gly Gly 35 40 <210> 411 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 411 aatcgcttct ctggctccaa gtctggcaac gcggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcgg gtagtagcac ttatgtggta 120 ttcggcgga 129 <210> 412 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 412 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ala Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Val Val Phe Gly Gly 35 40 <210> 413 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 413 aatcgcttct ctggctccaa gtctggcaac actgcctccc tgacaatctc tgggctccag 60 gctgagtacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttatgtggta 120 ttcggcgga 129 <210> 414 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 414 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Tyr Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Val Val Phe Gly Gly 35 40 <210> 415 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 415 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttatgtggta 120 ttcggcgga 129 <210> 416 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 416 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Val Val Phe Gly Gly 35 40 <210> 417 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 417 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac gtatgtggta 120 ttcggcgga 129 <210> 418 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 418 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ctatgtggta 120 ttcggcgga 129 <210> 419 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 419 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac atatgtggta 120 ttcggcgga 129 <210> 420 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 420 aatcgcttct ctggctccaa gtctcgcaac acggcctacc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttatgtggta 120 ttcggcgga 129 <210> 421 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 421 Asn Arg Phe Ser Gly Ser Lys Ser Arg Asn Thr Ala Tyr Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Val Val Phe Gly Gly 35 40 <210> 422 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 422 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttatgtggta 120 ttcggcgga 129 <210> 423 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 423 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Val Val Phe Gly Gly 35 40 <210> 424 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 424 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac gtatgtggta 120 ttcggcgga 129 <210> 425 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 425 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ctatgtggta 120 ttcggcgga 129 <210> 426 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 426 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac atatgtggta 120 ttcggcgga 129 <210> 427 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 427 atacgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttatgtggta 120 ttcggcgga 129 <210> 428 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 428 atacgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac atatgtggta 120 ttcggcgga 129 <210> 429 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 429 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Tyr Val Phe 1 5 10 <210> 430 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 430 tatcgcttct ctggctccaa gtctggcaac tcggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttttatgtc 120 ttcggaact 129 <210> 431 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 431 Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 432 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 432 attcgcttct ctggctccat gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttttatgtc 120 ttcggaact 129 <210> 433 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 433 Ile Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 434 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 434 actcgcttct ctggctccaa gtcttgcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttttatgtc 120 ttcggaact 129 <210> 435 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 435 Thr Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 436 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 436 aatcgcttct ctggctgcaa gtctggcatc acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttttatgtc 120 ttcggaact 129 <210> 437 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 437 Asn Arg Phe Ser Gly Cys Lys Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 438 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 438 aatcgcttct ctggctccaa gtctggctac acggcctccc tgacattctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttttatgtc 120 ttcggaact 129 <210> 439 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 439 Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr Phe 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 440 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 440 aatcgcttct ctggctccaa gtctggctac acggcctccc tgacaatctc tgggctcctg 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac cttttatgtc 120 ttcggaact 129 <210> 441 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 441 Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 442 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 442 aatcgcttct ctggctccaa gtctggcatc acggcctccc tgacaatctc ttggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttctatgtc 120 ttcggaact 129 <210> 443 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 443 Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 444 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 444 aatcgcttct ctggctccaa gtctggcaag acggcctccc tgactatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttttatgtc 120 ttcggaact 129 <210> 445 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 445 Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 446 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 446 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacattctc tgggctccag 60 gctgaggtcg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttttatgtc 120 ttcggaact 129 <210> 447 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 447 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Phe 1 5 10 15 Ser Gly Leu Gln Ala Glu Val Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 448 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 448 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgtgctccag 60 gctgatgacg aggctgatta ttactgctgc tcatatgcag gtagtagcac cttttatgtc 120 ttcggaact 129 <210> 449 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 449 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Val Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 450 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 450 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 tctgatgacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttttatgtc 120 ttcggaact 129 <210> 451 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 451 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ser Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 452 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 452 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttttatgtc 120 ttcggaact 129 <210> 453 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 453 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 454 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 454 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttctatgtc 120 ttcggaact 129 <210> 455 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 455 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac cttttatgtc 120 ttcggaact 129 <210> 456 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 456 aatcacttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagcagcac tttttatgtc 120 ttcggaact 129 <210> 457 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 457 Asn His Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 458 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 458 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttttatgtc 120 ttcggaact 129 <210> 459 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 459 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 460 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 460 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac cttttatgtc 120 ttcggaact 129 <210> 461 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 461 Cys Ser Tyr Ala Gly Ser Tyr Thr Leu Val Phe 1 5 10 <210> 462 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 462 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 463 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 463 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 464 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 464 ctgatccgct tctctggctc caagtctgac aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 465 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 465 Leu Ile Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 466 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 466 cctgatcgct tctctgtctc caagtctggc aacacggcct cgctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 467 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 467 Pro Asp Arg Phe Ser Val Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 468 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 468 cctgatcgct tctctggctg caagtctggc aactcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 469 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 469 Pro Asp Arg Phe Ser Gly Cys Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 470 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 470 cctgatcgct tctctggctc caagtctggc aactctgcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 471 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 471 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 472 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 472 cctgatcgct tctctggctc caagtctggc aactcgggct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 473 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 473 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Gly Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 474 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 474 cctgatcgct tctctggctc caagtctggc aacactgcct cccagaccat ctctggactc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 475 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 475 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Gln Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 476 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 476 cctgatcgct tctctggctc caagtctggc aacacggcct cgctgtccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 477 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 477 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 478 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 478 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 479 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 479 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 480 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 480 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctggactc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 481 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 481 cctgatcgct tctctggctc caagtctgac tactcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 482 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 482 Pro Asp Arg Phe Ser Gly Ser Lys Ser Asp Tyr Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 483 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 483 cctgatcgct tctctggctc caagtctgac aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcgtatg caggcagcta tactttggta 120 ttcggcgga 129 <210> 484 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 484 Pro Asp Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 485 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 485 cctgatcgct tctctggctc caagtctgac aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 486 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 486 ccgcttcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 487 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 487 Pro Leu Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 488 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 488 ccgcatcgct tctctggctc caagtctgac aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 489 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 489 Pro His Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 490 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 490 cagtttcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 491 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 491 Gln Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 492 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 492 cagttccgct tctctggctc caagtctgac aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttggta 120 ttcggcgga 129 <210> 493 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 493 Gln Phe Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 494 <211> 6 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 494 Cys Ser Phe Arg Val Phe 1 5 <210> 495 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 495 cgtccctcag tggtttctaa tcgcttctct ggctccaagt ctgtcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 496 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 496 Arg Pro Ser Val Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Val Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 497 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 497 cggccctcag gggtttctta tcgcttctct ggctccaagt ctggcaactc ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 498 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 498 Arg Pro Ser Gly Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn 1 5 10 15 Ser Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 499 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 499 cggccctcag gggtttctta tcgcttctct ggctccaagt ctcgcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 500 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 500 Arg Pro Ser Gly Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Arg Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 501 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 501 cggccctcag gggtttctaa tcgcttctct gtctccaagt ctgtcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 502 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 502 Arg Pro Ser Gly Val Ser Asn Arg Phe Ser Val Ser Lys Ser Val Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 503 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 503 cggccctcag gggtttctaa tcgcttctct ggctccaagt ctggcatcac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggatct 129 <210> 504 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 504 Arg Pro Ser Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Ser 35 40 <210> 505 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 505 cggccctcag gggtttctaa tcgcttctct ggctccaagt ctggcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 506 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 506 Arg Pro Ser Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 507 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 507 cggccctcag gggtttctaa tcgcttctct ggccccaagt ctggcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgaa gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 508 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 508 Arg Pro Ser Gly Val Ser Asn Arg Phe Ser Gly Pro Lys Ser Gly Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 509 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 509 cggccctcag gggtctctaa tcgcttctct ggctccaagt ctggcaacac ggcctccctg 60 acaacctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 510 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 510 Arg Pro Ser Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn 1 5 10 15 Thr Ala Ser Leu Thr Thr Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 511 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 511 aggccctcag gggtttctaa tcgcttctct ggctccaagt ctggcaacac ggcctccctg 60 acattctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 512 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 512 Arg Pro Ser Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn 1 5 10 15 Thr Ala Ser Leu Thr Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 513 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 513 ggccctcagg ggtttctaat ccgcttctct ggctccaagt ctggcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 514 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 514 Gly Pro Gln Gly Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 515 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 515 ggccctcagg gggttctaat acgcttctct ggctccaagt ctggcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 516 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 516 Gly Pro Gln Gly Val Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 517 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 517 cggccctcag gggtttctaa tcgcttctct ggctccaagt ctggcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt cctgctgctc atttagggtc 120 ttcggaact 129 <210> 518 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 518 Arg Pro Ser Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Ser Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 519 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 519 gcggcctcag gggtttctaa tcgcttctct ggctccaagt ctggcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 520 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 520 Ala Ala Ser Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 521 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 521 gcggccctca gggtttctaa tcgcttctct ggctccaagt ctggcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 522 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 522 Ala Ala Leu Arg Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 523 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 523 gcggccctca ggggtttcta tcgcttctct ggctccaagt ctggcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 524 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 524 Ala Ala Leu Arg Gly Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 525 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 525 agcggccctc aggggtttaa tcgcttctct ggctccaagt ctggcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagggtc 120 ttcggaact 129 <210> 526 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 526 Ser Gly Pro Gln Gly Phe Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Arg Val Phe Gly Thr 35 40 <210> 527 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 527 Cys Ser Tyr Ala Gly Ser Ser Thr Trp Val Phe 1 5 10 <210> 528 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 528 tgtaatcgcg tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 529 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 529 Cys Asn Arg Val Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 530 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 530 tcttatcgct tctctggctc caagtctggc aactcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 531 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 531 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 532 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 532 tcttatcgct tctctggctc caagtctggc aacacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 533 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 533 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 534 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 534 tctattcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 535 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 535 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 536 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 536 tctagtcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctccgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 537 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 537 Ser Ser Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 538 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 538 tctaatcgct tctctggctc gaagtctggc aacacggcct ccctgacatt ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 539 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 539 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 540 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 540 tctaatcgct tctctggctc catgtctggc atcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 541 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 541 Ser Asn Arg Phe Ser Gly Ser Met Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 542 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 542 tctaatcgct tctctggctc caagtctggg aactcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 543 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 543 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 544 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 544 tctaatcgct tctctggctc caagtctggc tacacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 545 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 545 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 546 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 546 tctaatcgct tctctggctc caagtctggc atcacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 547 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 547 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 548 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 548 tctaatcgct tctctggctc caagtctggc aagacggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 549 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 549 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 550 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 550 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 551 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 551 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 552 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 552 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 553 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 553 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 554 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 554 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 555 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 555 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Trp Val Phe Gly Gly 35 40 <210> 556 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 556 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgttcatatg caggtagtag cacttgggtg 120 ttcggcgga 129 <210> 557 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 557 Cys Ser Tyr Ala Gly Ser Ser Thr Cys Val Phe 1 5 10 <210> 558 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 558 ttctatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgcgtc 120 ttcggaact 129 <210> 559 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 559 Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Cys Val Phe Gly Thr 35 40 <210> 560 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 560 tgcaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgcgtc 120 ttcggaact 129 <210> 561 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 561 Cys Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Cys Val Phe Gly Thr 35 40 <210> 562 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 562 tctaatcgct tctctggctc catgtctggc aacacggcgt ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgcgtc 120 ttcggaact 129 <210> 563 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 563 Ser Asn Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Cys Val Phe Gly Thr 35 40 <210> 564 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 564 tctaatcgct tctctggctc caagtctggc aagacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgtgtc 120 ttcggaact 129 <210> 565 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 565 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Cys Val Phe Gly Thr 35 40 <210> 566 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 566 tctaatcgct tctctggctc caagtctggc aactcgtcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgtgtc 120 ttcggaact 129 <210> 567 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 567 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ser Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Cys Val Phe Gly Thr 35 40 <210> 568 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 568 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgcgtc 120 ttcggaact 129 <210> 569 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 569 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Cys Val Phe Gly Thr 35 40 <210> 570 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 570 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgcgtc 120 ttcggaact 129 <210> 571 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 571 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Cys Val Phe Gly Thr 35 40 <210> 572 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 572 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgacaat ctcttggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgtgtc 120 ttcggaact 129 <210> 573 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 573 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Cys Val Phe Gly Thr 35 40 <210> 574 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 574 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgtgtc 120 ttcggaact 129 <210> 575 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 575 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Cys Val Phe Gly Thr 35 40 <210> 576 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 576 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgcgtc 120 ttcggaact 129 <210> 577 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 577 tctaatcgct tctctggctc caagtctggc aacacggcct acctgacaat ctctgggctc 60 cagtctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgtgtc 120 ttcggaact 129 <210> 578 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 578 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Tyr Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Cys Val Phe Gly Thr 35 40 <210> 579 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 579 tctaatcgca tctctggctc caagtctggc aacacggcct cccagacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgcgtc 120 ttcggaact 129 <210> 580 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 580 Ser Asn Arg Ile Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Gln Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Cys Val Phe Gly Thr 35 40 <210> 581 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 581 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgtgtc 120 ttcggaact 129 <210> 582 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 582 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Cys Val Phe Gly Thr 35 40 <210> 583 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 583 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttgcgtc 120 ttcggaact 129 <210> 584 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 584 ttctatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgtc 120 ttcggaact 129 <210> 585 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 585 Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Thr 35 40 <210> 586 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 586 tctagtcgct cctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgtc 120 ttcggaact 129 <210> 587 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 587 Ser Ser Arg Ser Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Thr 35 40 <210> 588 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 588 tctaatggct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 cagtctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgtc 120 ttcggaact 129 <210> 589 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 589 Ser Asn Gly Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Thr 35 40 <210> 590 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 590 tctaatcgct tctctggctc caagtctggc atctcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgtc 120 ttcggaact 129 <210> 591 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 591 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Thr 35 40 <210> 592 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 592 tctaatcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctctgtgctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgtc 120 ttcggaact 129 <210> 593 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 593 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Thr 35 40 <210> 594 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 594 tctaatcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctctgggctc 60 gaggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgtc 120 ttcggaact 129 <210> 595 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 595 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Thr 35 40 <210> 596 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 596 tctaatcgct tctctggctc caagtctggc aacactgcct acctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgtc 120 ttcggaact 129 <210> 597 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 597 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Tyr Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Thr 35 40 <210> 598 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 598 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgtcaat ctctgggctc 60 caggctgagg acgaggctga ttactactgc tgctcatatg cgggtagtag cactttcgtc 120 ttcggaact 129 <210> 599 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 599 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Thr 35 40 <210> 600 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 600 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttttgtc 120 ttcggatct 129 <210> 601 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 601 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Ser 35 40 <210> 602 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 602 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgtc 120 ttcggaact 129 <210> 603 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 603 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Thr 35 40 <210> 604 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 604 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagcag cactttcgtc 120 ttcggagct 129 <210> 605 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 605 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Ala 35 40 <210> 606 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 606 tctaatcgct tctctggctc caagtctggc aacacggcct cccagacaat ctcagggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgtc 120 ttcggaact 129 <210> 607 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 607 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Gln Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Thr 35 40 <210> 608 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 608 tctaatcgct tctccggccc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgtc 120 ttcggaact 129 <210> 609 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 609 Ser Asn Arg Phe Ser Gly Pro Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Thr 35 40 <210> 610 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 610 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgtc 120 ttcggaact 129 <210> 611 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 611 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Val Phe Gly Thr 35 40 <210> 612 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 612 Cys Ser Tyr Ala Gly Ser Tyr Ser Tyr Val Phe 1 5 10 <210> 613 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 613 ctgctacgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcttatgtc 120 ttcggaact 129 <210> 614 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 614 Leu Leu Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 615 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 615 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcttatgtc 120 ttcggaact 129 <210> 616 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 616 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 617 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 617 cctgatcgct tctctggctg caagtctggc atcacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcttatgtc 120 ttcggaact 129 <210> 618 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 618 Pro Asp Arg Phe Ser Gly Cys Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 619 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 619 cctgatcgct tctctggctc gaagtctggc aacacgtcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcttatgtc 120 ttcggaact 129 <210> 620 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 620 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ser Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 621 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 621 cctgatcgct tctctggctc caagtcttgc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cagttatgtc 120 ttcggaact 129 <210> 622 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 622 Pro Asp Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 623 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 623 cctgatcgct tctctggctc caagtctggc atcacggcct ccctgaccat ctctgtgctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcttatgtc 120 ttcggaact 129 <210> 624 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 624 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 625 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 625 cctgatcgct tctctggctc caagtctggc aactcggcct ccctgacgat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcttatgtc 120 ttcggaact 129 <210> 626 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 626 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 627 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 627 cctgatcgct tctctggctc caagtctggc aactcggcct ccctgacctt ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagtta ctcttatgtc 120 ttcggaact 129 <210> 628 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 628 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 629 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 629 cctgatcgct tctctggctc caagtctggc aacactgcct ccctgaccat ctctgggctc 60 cagtctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcttatgtc 120 ttcggaact 129 <210> 630 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 630 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 631 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 631 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattatcgc tgctcatatg caggcagcta ctcttatgtc 120 ttcggaact 129 <210> 632 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 632 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Arg Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 633 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 633 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcttatgtc 120 ttcggaact 129 <210> 634 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 634 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 635 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 635 cctgatcgct gctctggctc caagtctggc aacacggcct ccctgaccat ctctggtctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcttatgtc 120 ttcggaact 129 <210> 636 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 636 Pro Asp Arg Cys Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 637 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 637 actgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcttatgtc 120 ttcggtact 129 <210> 638 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 638 Thr Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 639 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 639 actgatcgct tctctggccc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcttatgtc 120 ttcggaact 129 <210> 640 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 640 Thr Asp Arg Phe Ser Gly Pro Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Tyr Val Phe Gly Thr 35 40 <210> 641 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 641 Cys Ser Tyr Ala Gly Ser Tyr Thr His Val Val Phe 1 5 10 <210> 642 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 642 gatcgcttct ctggctgcaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcatgtggtt 120 ttcggcgga 129 <210> 643 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 643 Asp Arg Phe Ser Gly Cys Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Val Val Phe Gly Gly 35 40 <210> 644 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 644 gatcgcttct ctggctccaa gtctggctac acggcctccc tgacgatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcatgtggta 120 ttcggcgga 129 <210> 645 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 645 Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Val Val Phe Gly Gly 35 40 <210> 646 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 646 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgtgctccag 60 gctgaggatg atgctgatta ttactgctgc tcatatgcag gcagctacac tcatgtggta 120 ttcggcgga 129 <210> 647 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 647 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Val Leu Gln Ala Glu Asp Asp Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Val Val Phe Gly Gly 35 40 <210> 648 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 648 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgtgctccag 60 gctgaggatg agtctgatta ttactgctgc tcatatgcag gcagctacac tcatgtggta 120 ttcggcgga 129 <210> 649 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 649 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Val Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Val Val Phe Gly Gly 35 40 <210> 650 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 650 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggttccag 60 gctgaggatg aggccgatta ttactgctgc tcatatgcag gcagctacac tcatgtggta 120 ttcggcgga 129 <210> 651 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 651 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Phe Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Val Val Phe Gly Gly 35 40 <210> 652 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 652 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcatgtggta 120 ttcggcgga 129 <210> 653 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 653 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Val Val Phe Gly Gly 35 40 <210> 654 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 654 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gccgaggatg aggatgatta ttactgctgc tcatatgcag gcagctacac tcatgtggta 120 ttcggcgga 129 <210> 655 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 655 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Asp Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Val Val Phe Gly Gly 35 40 <210> 656 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 656 gatcgcttct ctggctccaa gtctggcaac acggactccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcatgttgta 120 ttcggcgga 129 <210> 657 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 657 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Asp Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Val Val Phe Gly Gly 35 40 <210> 658 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 658 gatcgcttct ctggctccaa gtccggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcatgtggtg 120 ttcggcgga 129 <210> 659 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 659 gatcgcttct ctggctccaa gcctggcaac acggcccccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcatgtggta 120 ttcggcgga 129 <210> 660 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 660 Asp Arg Phe Ser Gly Ser Lys Pro Gly Asn Thr Ala Pro Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Val Val Phe Gly Gly 35 40 <210> 661 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 661 gatcgattct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgagtatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcatgtggta 120 ttcggcgga 129 <210> 662 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 662 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Tyr Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Val Val Phe Gly Gly 35 40 <210> 663 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 663 tttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcatgtggta 120 ttcggcgga 129 <210> 664 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 664 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Val Val Phe Gly Gly 35 40 <210> 665 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 665 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcatgtggta 120 ttcggcgga 129 <210> 666 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 666 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Val Val Phe Gly Gly 35 40 <210> 667 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 667 Cys Ser Tyr Ala Gly Ser Tyr Thr Leu Tyr Val Phe 1 5 10 <210> 668 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 668 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccttctc tgggctcctg 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac cctttatgtc 120 ttcggaact 129 <210> 669 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 669 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Phe 1 5 10 15 Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Tyr Val Phe Gly Thr 35 40 <210> 670 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 670 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tctttatgtc 120 ttcggaact 129 <210> 671 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 671 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Tyr Val Phe Gly Thr 35 40 <210> 672 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 672 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac cctttatgtc 120 ttcggaact 129 <210> 673 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 673 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatat ttactgctgc tcatatgcag gcagctacac tctttatgtc 120 ttcggaact 129 <210> 674 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 674 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Ile Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Tyr Val Phe Gly Thr 35 40 <210> 675 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 675 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgagaatg aggctgacta ttactgctgc tcatatgcag gcagctacac cctttatgtc 120 ttcggaact 129 <210> 676 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 676 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asn Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Tyr Val Phe Gly Thr 35 40 <210> 677 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 677 gatcgattct ctggctccaa gtctggcaac acggcctacc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tctttatgtc 120 ttcggaact 129 <210> 678 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 678 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Tyr Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Tyr Val Phe Gly Thr 35 40 <210> 679 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 679 tttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tctttatgtc 120 ttcggaact 129 <210> 680 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 680 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Tyr Val Phe Gly Thr 35 40 <210> 681 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 681 ttccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tctttatgtc 120 ttcggaact 129 <210> 682 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 682 ttccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac cctttatgtc 120 ttcggaact 129 <210> 683 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 683 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tctttatgtc 120 ttcggaact 129 <210> 684 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 684 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Tyr Val Phe Gly Thr 35 40 <210> 685 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 685 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac cctttatgtc 120 ttcggaact 129 <210> 686 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 686 atacgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tctttatgtc 120 ttcggaact 129 <210> 687 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 687 gtgatcgctt ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tctttatgtc 120 ttcggaact 129 <210> 688 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 688 Val Ile Ala Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Tyr Val Phe Gly Thr 35 40 <210> 689 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 689 Cys Ser Tyr Ala Gly Ser Ser Thr Pro Val Val Phe 1 5 10 <210> 690 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 690 attcgcttct ctggctccaa gtctggcaag acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tcccgtggta 120 ttcggcgga 129 <210> 691 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 691 Ile Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Val Val Phe Gly Gly 35 40 <210> 692 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 692 attcgcttct ctggctccaa gtctggcaac tcggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ccctgtggta 120 ttcggcgga 129 <210> 693 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 693 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Val Val Phe Gly Gly 35 40 <210> 694 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 694 attcgcttct ctggctccaa gtctggcaac acggcctgcc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tccggtggta 120 ttcggcgga 129 <210> 695 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 695 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Cys Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Val Val Phe Gly Gly 35 40 <210> 696 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 696 aatcgcttgt ctggctccaa gtctggcatc acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tcccgtggta 120 ttcggcgga 129 <210> 697 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 697 Asn Arg Leu Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Val Val Phe Gly Gly 35 40 <210> 698 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 698 aatcgcttct ctggctccaa gtctggcatc acggcctccc tgtcaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tcccgtggta 120 ttcggcgga 129 <210> 699 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 699 Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Val Val Phe Gly Gly 35 40 <210> 700 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 700 aatcgcttct ctggctccaa gtctggcaac tctgcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tccggtggta 120 ttcggcgga 129 <210> 701 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 701 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Val Val Phe Gly Gly 35 40 <210> 702 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 702 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gttgaggacg tggctgatta ttactgctgc tcatatgcag gtagtagcac tcccgtggta 120 ttcggcgga 129 <210> 703 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 703 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Val Glu Asp Val Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Val Val Phe Gly Gly 35 40 <210> 704 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 704 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tccggtggta 120 ttcggcgga 129 <210> 705 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 705 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Val Val Phe Gly Gly 35 40 <210> 706 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 706 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tcccgtggta 120 ttcggcgga 129 <210> 707 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 707 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ccctgtggta 120 ttcggcgga 129 <210> 708 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 708 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tccggtggta 120 ttcggcgga 129 <210> 709 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 709 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Val Val Phe Gly Gly 35 40 <210> 710 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 710 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tcccgtggta 120 ttcggcgga 129 <210> 711 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 711 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ccctgtggta 120 ttcggcgga 129 <210> 712 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 712 Cys Ser Tyr Ala Gly Ser Trp Val Phe 1 5 <210> 713 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 713 ggggttctta tccgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggta 120 ttcggcgga 129 <210> 714 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 714 Gly Val Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Trp Val Phe Gly Gly 35 40 <210> 715 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 715 gggtttctaa tccgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggta 120 ttcggcgga 129 <210> 716 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 716 Gly Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Trp Val Phe Gly Gly 35 40 <210> 717 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 717 ggggtttctt atcgcttctc tggctccaag tctggcaact cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggta 120 ttcggcgga 129 <210> 718 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 718 Gly Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Trp Val Phe Gly Gly 35 40 <210> 719 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 719 ggggtttctt atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctcctgg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggta 120 ttcggcgga 129 <210> 720 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 720 Gly Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Trp Val Phe Gly Gly 35 40 <210> 721 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 721 ggggtttcta atcgcttctc tggctccatg tctggcaaca cggcctccct gacaatctct 60 tggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggtg 120 ttcggcgga 129 <210> 722 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 722 Gly Val Ser Asn Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Trp Val Phe Gly Gly 35 40 <210> 723 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 723 ggggtttcta atcgcttctc tggctccaag tctggctaca cggcctccct gacaatctct 60 gggctcgagg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggta 120 ttcggcgga 129 <210> 724 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 724 Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Trp Val Phe Gly Gly 35 40 <210> 725 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 725 ggggtttcta atcgcttctc tggctccaag tctggcaaca cggcctccct gtctatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggtg 120 ttcggcgga 129 <210> 726 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 726 Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Ser Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Trp Val Phe Gly Gly 35 40 <210> 727 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 727 ggggtttcta atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggtg 120 ttcggcgga 129 <210> 728 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 728 Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Trp Val Phe Gly Gly 35 40 <210> 729 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 729 ggggtttcta atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggta 120 ttcggcgga 129 <210> 730 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 730 ggggtttcta atcgcttctc tggctccaag cctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcggg tagttgggta 120 ttcggcgga 129 <210> 731 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 731 Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Pro Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Trp Val Phe Gly Gly 35 40 <210> 732 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 732 ggggttgata atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggta 120 ttcggcgga 129 <210> 733 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 733 Gly Val Asp Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Trp Val Phe Gly Gly 35 40 <210> 734 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 734 gggggttctt atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggta 120 ttcggcgga 129 <210> 735 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 735 Gly Gly Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Trp Val Phe Gly Gly 35 40 <210> 736 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 736 Cys Ser Tyr Ala Gly Ser Tyr Pro Arg Leu 1 5 10 <210> 737 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 737 gtccctgatc gcttctctgg ctccaggtct gacaacacgg cctccctgac catctctggt 60 ctcctggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacccccgc 120 ctcggaact 129 <210> 738 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 738 Val Pro Asp Arg Phe Ser Gly Ser Arg Ser Asp Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Pro Arg Leu Gly Thr 35 40 <210> 739 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 739 gtccctgatc gcttctctgg ctccaagtct gacaagtcgg cctccctgac catctctggt 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacccccgc 120 ctcggaact 129 <210> 740 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 740 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Asp Lys Ser Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Pro Arg Leu Gly Thr 35 40 <210> 741 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 741 gtccctgatc gcttctctgg ctccaagtct gacaacaggg cctccctgac cttctctggt 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacccccgc 120 ctcggaact 129 <210> 742 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 742 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Asp Asn Arg Ala Ser Leu 1 5 10 15 Thr Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Pro Arg Leu Gly Thr 35 40 <210> 743 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 743 gtccctgatc gcttctctgg ctccaagtct gacaacacgg cctccctgtc gatctctggt 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacccccgc 120 ctcggaact 129 <210> 744 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 744 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu 1 5 10 15 Ser Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Pro Arg Leu Gly Thr 35 40 <210> 745 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 745 gtccctgatc gcttctctgg ctccaagtct gacaacacgg cctccctgac catctctggt 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacccccgc 120 ctcggaact 129 <210> 746 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 746 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Pro Arg Leu Gly Thr 35 40 <210> 747 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 747 gtccctgatc gcttctctgg ctccaagtct gacaacacgg cctccctgac catctctggt 60 ctccaggctg aggatgaggc taattattac tgctgctcat atgcaggcag ctacccccgc 120 ctcggaacc 129 <210> 748 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 748 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asn Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Pro Arg Leu Gly Thr 35 40 <210> 749 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 749 gtccctgatc gcttctctgg ctccaagtct gacaacacgg cccccctgac catctctgat 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacccccgc 120 ctcggaact 129 <210> 750 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 750 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Pro Leu 1 5 10 15 Thr Ile Ser Asp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Pro Arg Leu Gly Thr 35 40 <210> 751 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 751 gtccctgatc gcttctctgg ctccaagcct gacaacacgg cctccccgac catctctggt 60 ctccaggctg aggataaggc tgattattac tgctgctcat atgcaggcag ctacccccgc 120 ctcggaact 129 <210> 752 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 752 Val Pro Asp Arg Phe Ser Gly Ser Lys Pro Asp Asn Thr Ala Ser Pro 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Lys Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Pro Arg Leu Gly Thr 35 40 <210> 753 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 753 gtccctgatc gcttctctgg ctccaaatct gacaacacgg cctccctgac catctctggt 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacccccgc 120 ctcggaacc 129 <210> 754 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 754 gtccctgacc gcttctctgg ctccaagtct gacaacacgg cctccctgac catctctggt 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacccccgt 120 ctcggaact 129 <210> 755 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 755 gtcccgtttc gcttctctgg ctccaagtct gacaacacgg cctccctgac catctctggt 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacccccgc 120 ctcggaact 129 <210> 756 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 756 Val Pro Phe Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Pro Arg Leu Gly Thr 35 40 <210> 757 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 757 gtacctgatc gcttctctgg ctccaagtct gacaacacgg cctccctgac catctcttgt 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacccccgc 120 ctcggaact 129 <210> 758 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 758 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Cys Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Pro Arg Leu Gly Thr 35 40 <210> 759 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 759 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Val Val Phe 1 5 10 <210> 760 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 760 gttcgcttct ctggctcgaa gtctggcaac gcggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgtggta 120 ttcggcgga 129 <210> 761 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 761 Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Ala Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Gly 35 40 <210> 762 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 762 gttcgcttct ctggctccaa gtctggcatc gcggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgtggta 120 ttcggcgga 129 <210> 763 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 763 Val Arg Phe Ser Gly Ser Lys Ser Gly Ile Ala Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Gly 35 40 <210> 764 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 764 gatcgcttct ctggctccaa gtctggcaac gcggcctccc tgaccatctc ttggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgttgta 120 ttcggcgga 129 <210> 765 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 765 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ala Ala Ser Leu Thr Ile 1 5 10 15 Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Gly 35 40 <210> 766 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 766 gatcgcttct ctggctccaa gtctggcaac gcggcctccc tgaccatctc tgggctccag 60 gctgaggatg gggctgatta ttactgctgc tcatatgcag gcagctacac tttcgtggta 120 ttcggcggc 129 <210> 767 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 767 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ala Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Gly Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Gly 35 40 <210> 768 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 768 gatcgcttct ctggctccaa gtctggcaac gcggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgtggta 120 ttcggcgga 129 <210> 769 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 769 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ala Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Gly 35 40 <210> 770 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 770 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttttgtggta 120 ttcggcgga 129 <210> 771 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 771 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Gly 35 40 <210> 772 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 772 gatcgattct ctggctccaa gtctggcaac gcggcctccc tgaccatctc ttggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgtggta 120 ttcggcgga 129 <210> 773 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 773 tttcgcttct ctggctccaa gtctggcaac gcggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgtggta 120 ttcggcgga 129 <210> 774 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 774 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Ala Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Gly 35 40 <210> 775 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 775 tttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttttgtggta 120 ttcggcgga 129 <210> 776 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 776 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Gly 35 40 <210> 777 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 777 gttcgcttct ctggctccaa gtctggcaac gcggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgtggta 120 ttcggcgga 129 <210> 778 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 778 atccgcttct ctggctccaa gtctggcaac gcggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgtggta 120 ttcggcgga 129 <210> 779 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 779 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Ala Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Gly 35 40 <210> 780 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 780 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttttgtggta 120 ttcggcgga 129 <210> 781 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 781 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Gly 35 40 <210> 782 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 782 Cys Ser Tyr Ala Gly Ser Asp Thr Leu Val Leu 1 5 10 <210> 783 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 783 ctgatccgct tctctggctc caggtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgt tgctcatatg caggcagcga cactttggta 120 ctcggcgga 129 <210> 784 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 784 Leu Ile Arg Phe Ser Gly Ser Arg Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Asp Thr Leu Val Leu Gly Gly 35 40 <210> 785 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 785 cgtgatcgct tctctggctc ctggtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgt tgctcatatg caggcagcga cactttggta 120 ctcggcgga 129 <210> 786 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 786 Arg Asp Arg Phe Ser Gly Ser Trp Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Asp Thr Leu Val Leu Gly Gly 35 40 <210> 787 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 787 cctgatcgct tctctggctc catgtctggc aacacggcct ccctgtccat ctctgggctc 60 caggctgagg atgaggctga ttattactgt tgctcatatg caggcagcga cactttggta 120 ctcggcgga 129 <210> 788 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 788 Pro Asp Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Asp Thr Leu Val Leu Gly Gly 35 40 <210> 789 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 789 cctgatcgct tctctggctc catgtctggc aacacggcct ccctgaccat ctctgggctc 60 cagtctgagg atgaggctga ttattactgt tgctcatatg caggcagcga cactttggta 120 ctcggcgga 129 <210> 790 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 790 Pro Asp Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Asp Thr Leu Val Leu Gly Gly 35 40 <210> 791 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 791 cctgatcgct tctctggctc catgtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgagtctga ttattactgt tgctcatatg caggcagcga cactttggta 120 ctcggcgga 129 <210> 792 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 792 Pro Asp Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Asp Thr Leu Val Leu Gly Gly 35 40 <210> 793 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 793 cctgatcgct tctctggctc caggtctggc tacacggcct ccctgacgat ctctgggctc 60 caggctgagg atgaggctga ttattactgt tgctcatatg caggcagcga cactttggta 120 ctcggcgga 129 <210> 794 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 794 Pro Asp Arg Phe Ser Gly Ser Arg Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Asp Thr Leu Val Leu Gly Gly 35 40 <210> 795 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 795 cctgatcgct tctctggctc caggtctggc aactcggcct ccctgaccat ctctgggctc 60 caggctgatg atgaggctga ttattactgt tgctcatatg caggcagcga cactttggta 120 ctcggcgga 129 <210> 796 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 796 Pro Asp Arg Phe Ser Gly Ser Arg Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Asp Thr Leu Val Leu Gly Gly 35 40 <210> 797 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 797 cctgatcgct tctctggctc caggtctggc aacacggcct cccttaccat ctctgggctc 60 ctggctgagg atgaggctga ttattactgt tgctcatatg caggcagcga cactttggta 120 ctcggcgga 129 <210> 798 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 798 Pro Asp Arg Phe Ser Gly Ser Arg Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Asp Thr Leu Val Leu Gly Gly 35 40 <210> 799 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 799 cctgatcgct tctctggctc caggtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgt tgctcatatg caggcagcga cactttggta 120 ctcggcgga 129 <210> 800 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 800 Pro Asp Arg Phe Ser Gly Ser Arg Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Asp Thr Leu Val Leu Gly Gly 35 40 <210> 801 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 801 cctgaccgct tctctggctc caggtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgt tgctcatatg caggtagcga cactttggta 120 ctcggcgga 129 <210> 802 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 802 cctgaccgct tctctggctc caggtctggc aacacggcct ccctgaccac ctctgggctc 60 caggctgagg atgaggctga ttattactgt tgctcatatg caggcagcga cactttggta 120 ctcggcgga 129 <210> 803 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 803 Pro Asp Arg Phe Ser Gly Ser Arg Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Thr Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Asp Thr Leu Val Leu Gly Gly 35 40 <210> 804 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 804 cctgatcgct tctctggctc caggtctggc aacacggcct ccctgaccat ctctgtgctc 60 caggctgagg atgaggctga ttattactgt tgctcatatg caggcagcga cactttggta 120 ctcggcgga 129 <210> 805 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 805 Pro Asp Arg Phe Ser Gly Ser Arg Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Asp Thr Leu Val Leu Gly Gly 35 40 <210> 806 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 806 Cys Ser Tyr Ala Gly Ser Ser Thr Ser Val Val Phe 1 5 10 <210> 807 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 807 gaccgattct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcgtatgcag gtagtagcac ctctgtggta 120 ttcggcgga 129 <210> 808 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 808 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Val Val Phe Gly Gly 35 40 <210> 809 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 809 aatcgcttct gtggctcgaa gtctggcaac tcggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttctgtggta 120 ttcggcgga 129 <210> 810 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 810 Asn Arg Phe Cys Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Val Val Phe Gly Gly 35 40 <210> 811 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 811 aatcgcttct cttgctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg agtctgatta ttactgctgc tcatatgcag gtagtagcac ttctgtggta 120 ttcggcgga 129 <210> 812 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 812 Asn Arg Phe Ser Cys Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Val Val Phe Gly Gly 35 40 <210> 813 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 813 aatcgcttct ctggctccaa gtctgtcaac acggcctccc tgacaatctc tgggctccag 60 tctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttctgtggta 120 ttcggcgga 129 <210> 814 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 814 Asn Arg Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Val Val Phe Gly Gly 35 40 <210> 815 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 815 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacattctc tgggctccag 60 tctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttctgtggta 120 ttcggcgga 129 <210> 816 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 816 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Phe 1 5 10 15 Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Val Val Phe Gly Gly 35 40 <210> 817 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 817 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttctgtggta 120 ttcggcgga 129 <210> 818 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 818 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Val Val Phe Gly Gly 35 40 <210> 819 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 819 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttccgtggta 120 ttcggcgga 129 <210> 820 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 820 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gcagtagcac ttccgtggta 120 ttcggcgga 129 <210> 821 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 821 aatcgcttct ctggccccaa gtctggcatc acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gcagtagcac ttccgtggta 120 ttcggcgga 129 <210> 822 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 822 Asn Arg Phe Ser Gly Pro Lys Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Val Val Phe Gly Gly 35 40 <210> 823 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 823 aatcgcttct caggctcgaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttctgtggta 120 ttcggcgga 129 <210> 824 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 824 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttctgtggta 120 ttcggcgga 129 <210> 825 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 825 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Val Val Phe Gly Gly 35 40 <210> 826 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 826 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gcagtagcac ttccgtggta 120 ttcggcgga 129 <210> 827 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 827 Cys Ser Phe Ala Gly Ser Tyr Thr Glu Val Phe 1 5 10 <210> 828 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 828 cctgatcgct tctctggctc caagtctggc agcacggcct ccctgaccct ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcta cacggaggta 120 ttcggcgga 129 <210> 829 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 829 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ser Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser Tyr Thr Glu Val Phe Gly Gly 35 40 <210> 830 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 830 gctgttcgct tctctggctc catgtctggc aacacggcct ccctgaccct ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcta cacggaggta 120 ttcggcgga 129 <210> 831 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 831 Ala Val Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser Tyr Thr Glu Val Phe Gly Gly 35 40 <210> 832 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 832 gctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccct ctctgggctc 60 caggctgagg atgaggctga ttatttctgc tgctcatttg caggcagcta cacggaggta 120 ttcggcgga 129 <210> 833 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 833 Ala Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Phe Ala Gly Ser Tyr Thr Glu Val Phe Gly Gly 35 40 <210> 834 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 834 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccct ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcta cacggaggta 120 ttcggcgga 129 <210> 835 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 835 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser Tyr Thr Glu Val Phe Gly Gly 35 40 <210> 836 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 836 cctgatcgct tctctggctc gatgtctggc aacacggcct ccctgaccct ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcta cacggaggta 120 ttcggcgga 129 <210> 837 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 837 Pro Asp Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser Tyr Thr Glu Val Phe Gly Gly 35 40 <210> 838 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 838 cctgatcgct tctctggctc catgtctggc aagacggcct ccctgaccct ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcta cacggaggta 120 ttcggcgga 129 <210> 839 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 839 Pro Asp Arg Phe Ser Gly Ser Met Ser Gly Lys Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser Tyr Thr Glu Val Phe Gly Gly 35 40 <210> 840 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 840 cctgatcgct tctctggctc caagtctggc aacacggcct cccttaccct ctctgtgctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcta cacggaggta 120 ttcggcgga 129 <210> 841 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 841 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser Tyr Thr Glu Val Phe Gly Gly 35 40 <210> 842 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 842 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgtccct ctctgtgctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcta cacggaggta 120 ttcggcgga 129 <210> 843 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 843 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser 1 5 10 15 Leu Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser Tyr Thr Glu Val Phe Gly Gly 35 40 <210> 844 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 844 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccct ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcta cacggaggta 120 ttcggcgga 129 <210> 845 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 845 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser Tyr Thr Glu Val Phe Gly Gly 35 40 <210> 846 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 846 ccgcttcgct tctctggctc caagtctggc aacacggcct ccctgaccct ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcta cacggaggta 120 ttcggcgga 129 <210> 847 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 847 Pro Leu Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser Tyr Thr Glu Val Phe Gly Gly 35 40 <210> 848 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 848 acagatcgct tctctggctc caagtctggc aacacggcct ccctgaccct ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcta cacggaggta 120 ttcggcgga 129 <210> 849 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 849 Thr Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser Tyr Thr Glu Val Phe Gly Gly 35 40 <210> 850 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 850 Cys Ser Tyr Ala Gly Ser Tyr Ser Tyr Val Val Phe 1 5 10 <210> 851 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 851 tttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctactc ttatgtggta 120 ttcggcgga 129 <210> 852 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 852 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ser Tyr Val Val Phe Gly Gly 35 40 <210> 853 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 853 gttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgtgctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctactc ctatgtggta 120 ttcggcgga 129 <210> 854 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 854 Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ser Tyr Val Val Phe Gly Gly 35 40 <210> 855 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 855 gatcgcttct ctggctgcaa gtctggcaac acggcctccc tgaccatctc ttggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctactc ctatgtggta 120 ttcggcgga 129 <210> 856 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 856 Asp Arg Phe Ser Gly Cys Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ser Tyr Val Val Phe Gly Gly 35 40 <210> 857 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 857 gatcgcttct ctggctccaa gtctggcatc acggcctccc tgtccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctactc ttatgtggta 120 ttcggcgga 129 <210> 858 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 858 Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ser Tyr Val Val Phe Gly Gly 35 40 <210> 859 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 859 gatcgcttct ctggctccaa gtctggcatc acggcctccc tgaccatctc tgggctccag 60 gctgatgatg aggctgatta ttactgctgc tcatatgcag gcagctactc ctatgtggta 120 ttcggcgga 129 <210> 860 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 860 Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ser Tyr Val Val Phe Gly Gly 35 40 <210> 861 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 861 gatcgcttct ctggctccaa gtctggcaac tcggcctccc tgtccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctactc ttatgtggta 120 ttcggcgga 129 <210> 862 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 862 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ser Tyr Val Val Phe Gly Gly 35 40 <210> 863 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 863 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctactc ttatgtggta 120 ttcggcgga 129 <210> 864 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 864 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ser Tyr Val Val Phe Gly Gly 35 40 <210> 865 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 865 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctactc ctatgtggta 120 ttcggcgga 129 <210> 866 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 866 gttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctactc ctatgtggta 120 ttcggcgga 129 <210> 867 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 867 Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ser Tyr Val Val Phe Gly Gly 35 40 <210> 868 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 868 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctactc ctatgtggta 120 ttcggcgga 129 <210> 869 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 869 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ser Tyr Val Val Phe Gly Gly 35 40 <210> 870 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 870 atacgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctactc ctatgtggta 120 ttcggcgga 129 <210> 871 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 871 Cys Ser Tyr Ala Gly Ser Ser Val Val Phe 1 5 10 <210> 872 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 872 tttctaatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcgtggta 120 ttcggcgga 129 <210> 873 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 873 Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Val Val Phe Gly Gly 35 40 <210> 874 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 874 gtttctaatg gcttctctgg ctccaagtct ggcaacacgg cctccctgac attctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcgtggta 120 ttcggcgga 129 <210> 875 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 875 Val Ser Asn Gly Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Val Val Phe Gly Gly 35 40 <210> 876 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 876 gtttctaatc gcttctctgg ctccaagtct ggcaagacgg cctccctgac tatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcgtggta 120 ttcggcgga 129 <210> 877 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 877 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Val Val Phe Gly Gly 35 40 <210> 878 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 878 gtttctaatc gcttctctgg ctccaagtct ggcaactcgg cctccctgac tatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcgtggta 120 ttcggcgga 129 <210> 879 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 879 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Val Val Phe Gly Gly 35 40 <210> 880 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 880 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgtc tatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcgtggta 120 ttcggcgga 129 <210> 881 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 881 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Ser Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Val Val Phe Gly Gly 35 40 <210> 882 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 882 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac tatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcgttgta 120 ttcggcgga 129 <210> 883 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 883 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Val Val Phe Gly Gly 35 40 <210> 884 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 884 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagtgtggta 120 ttcggcgga 129 <210> 885 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 885 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcgtggta 120 ttcggcgga 129 <210> 886 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 886 gtttctaata gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctcttgg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagtgtggta 120 ttcggcgga 129 <210> 887 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 887 Val Ser Asn Ser Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Val Val Phe Gly Gly 35 40 <210> 888 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 888 gtttataatc gcttctctgg ctccaagtct ggcaagacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcgtggta 120 ttcggcgga 129 <210> 889 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 889 Val Tyr Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Val Val Phe Gly Gly 35 40 <210> 890 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 890 gttctaatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcgtggta 120 ttcggcgga 129 <210> 891 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 891 Val Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Val Val Phe Gly Gly 35 40 <210> 892 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 892 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Gly Val Val Phe 1 5 10 <210> 893 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 893 cgcttctctg gctccatgtc tggcaacacg gcctccctga ctatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt cggtgtggta 120 ttcggcgga 129 <210> 894 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 894 Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 895 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 895 cgcttctctg gctccatgtc tggcaacacg gcctccctga caatctctgg gctcgaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt cggtgtggta 120 ttcggcgga 129 <210> 896 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 896 Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 897 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 897 cgcttctctg gctccaagtc ttgcaactcg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt cggagtggta 120 ttcggcgga 129 <210> 898 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 898 Arg Phe Ser Gly Ser Lys Ser Cys Asn Ser Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 899 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 899 cgcttctctg gctccaagtc tggctacacg gcctccctga ctatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt cggtgtggta 120 ttcggcgga 129 <210> 900 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 900 Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 901 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 901 cgcttctctg gctccaagtc tggcaactcg gcctccctga gaatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt cggagtggta 120 ttcggcgga 129 <210> 902 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 902 Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Arg Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 903 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 903 cgcttctctg gctccaagtc tggcaacacg gcctccctgt ctatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt cggtgtggta 120 ttcggcgga 129 <210> 904 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 904 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 905 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 905 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctcgaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt cggtgtggtt 120 ttcggcgga 129 <210> 906 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 906 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 907 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 907 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt cggtgtggta 120 ttcggcgga 129 <210> 908 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 908 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 909 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 909 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt cggagtggta 120 ttcggcgga 129 <210> 910 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 910 cgcttctctg gctacaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gatgacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt cggtgtggta 120 ttcggcgga 129 <210> 911 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 911 Arg Phe Ser Gly Tyr Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 912 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 912 tcgcttctct ggctccaagt ctggcaacac ggcctcctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt cggtgtggta 120 ttcggcgga 129 <210> 913 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 913 Ser Leu Leu Trp Leu Gln Val Trp Gln His Gly Leu Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 914 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 914 Cys Ser Tyr Ala Gly Ser Ser Gly Val Phe 1 5 10 <210> 915 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 915 gtttcttatc gcttctctgg ctccaagtgt ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcggggtg 120 ttcggcgga 129 <210> 916 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 916 Val Ser Tyr Arg Phe Ser Gly Ser Lys Cys Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Gly Val Phe Gly Gly 35 40 <210> 917 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 917 gtttcttatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctcttgg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcggggtg 120 ttcggcgga 129 <210> 918 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 918 Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Gly Val Phe Gly Gly 35 40 <210> 919 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 919 gtttcttatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctcgaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcggggtg 120 ttcggcgga 129 <210> 920 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 920 Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Gly Val Phe Gly Gly 35 40 <210> 921 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 921 gtttctaatc gcttctctgt ctccaagtct ggcaacacgg cctccctgac aacctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcggggtg 120 ttcggcgga 129 <210> 922 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 922 Val Ser Asn Arg Phe Ser Val Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Thr Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Gly Val Phe Gly Gly 35 40 <210> 923 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 923 gtttctaatc gcttctctgg ctccatgtct gtcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcggggtg 120 ttcggcgga 129 <210> 924 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 924 Val Ser Asn Arg Phe Ser Gly Ser Met Ser Val Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Gly Val Phe Gly Gly 35 40 <210> 925 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 925 gtttctaatc gcttctctgg ctccaagtct ggcatctcgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcggggtg 120 ttcggcgga 129 <210> 926 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 926 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Gly Val Phe Gly Gly 35 40 <210> 927 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 927 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgtc aatctcttgg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcggggtg 120 ttcggcgga 129 <210> 928 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 928 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Ser Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Gly Val Phe Gly Gly 35 40 <210> 929 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 929 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctgtg 60 ctccaggctg atgacgaggc tgattattac tgctgctcat atgcaggtag tagcggggtg 120 ttcggcgga 129 <210> 930 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 930 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Val Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Gly Val Phe Gly Gly 35 40 <210> 931 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 931 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcgggtag tagcggagtg 120 ttcggcgga 129 <210> 932 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 932 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Gly Val Phe Gly Gly 35 40 <210> 933 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 933 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcggggtg 120 ttcggcgga 129 <210> 934 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 934 gttctaatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcggggtg 120 ttcggcgga 129 <210> 935 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 935 Val Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Gly Val Phe Gly Gly 35 40 <210> 936 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 936 Cys Ser Tyr Ala Gly Ser Tyr Thr Leu Ala Val Phe 1 5 10 <210> 937 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 937 gttcgcttct ctggctccaa ggctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttggcggta 120 ttcggcgga 129 <210> 938 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 938 Val Arg Phe Ser Gly Ser Lys Ala Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Ala Val Phe Gly Gly 35 40 <210> 939 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 939 gatcgtttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta tcactgctgc tcatatgcag gcagctacac tttggcggta 120 ttcggcgga 129 <210> 940 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 940 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr His Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Ala Val Phe Gly Gly 35 40 <210> 941 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 941 gatcgcttct ctggctcgaa gtctggcaac acggcctgcc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttggcggta 120 ttcggcgga 129 <210> 942 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 942 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Cys Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Ala Val Phe Gly Gly 35 40 <210> 943 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 943 gatcgcttct ctggctccaa gtcttgcaac actgcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttggcggta 120 ttcggcgga 129 <210> 944 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 944 Asp Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Ala Val Phe Gly Gly 35 40 <210> 945 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 945 gatcgcttct ctggctccaa gtctggcaag acggcctccc tgaccatctc tgggctccag 60 gctgtggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttggcggta 120 ttcggcgga 129 <210> 946 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 946 Asp Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Val Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Ala Val Phe Gly Gly 35 40 <210> 947 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 947 gatcgcttct ctggctccaa gtctggcaac tcggcctccc tgaccatctc tgggctgcag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttggcggta 120 ttcggcgga 129 <210> 948 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 948 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Ala Val Phe Gly Gly 35 40 <210> 949 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 949 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttggcggta 120 ttcggcgga 129 <210> 950 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 950 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Ala Val Phe Gly Gly 35 40 <210> 951 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 951 gatcgcttct ctggctccaa ggctggcaac tcggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttggcggta 120 ttcggcgga 129 <210> 952 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 952 Asp Arg Phe Ser Gly Ser Lys Ala Gly Asn Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Ala Val Phe Gly Gly 35 40 <210> 953 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 953 gatagcttct ctggctccaa gtcttgcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttggcggta 120 ttcggcgga 129 <210> 954 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 954 Asp Ser Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Ala Val Phe Gly Gly 35 40 <210> 955 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 955 ttccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttggcggta 120 ttcggcgga 129 <210> 956 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 956 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Ala Val Phe Gly Gly 35 40 <210> 957 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 957 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttggcggta 120 ttcggcgga 129 <210> 958 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 958 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Ala Val Phe Gly Gly 35 40 <210> 959 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 959 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Ala Val Phe 1 5 10 <210> 960 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 960 gttcgcttct ctggcttcaa gtctggcaac acggcctccc tgaccatctc tgtgctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcggtg 120 ttcggcgga 129 <210> 961 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 961 Val Arg Phe Ser Gly Phe Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Val Phe Gly Gly 35 40 <210> 962 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 962 gatctcttct cttgctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcggtg 120 ttcggcgga 129 <210> 963 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 963 Asp Leu Phe Ser Cys Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Val Phe Gly Gly 35 40 <210> 964 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 964 gatcgcttct ctggcttcaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcggtg 120 ttcggcgga 129 <210> 965 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 965 Asp Arg Phe Ser Gly Phe Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Val Phe Gly Gly 35 40 <210> 966 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 966 gatcgcttct ctggctccaa gtctggcaag acggcctccc agaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcggtg 120 ttcggcgga 129 <210> 967 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 967 Asp Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Gln Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Val Phe Gly Gly 35 40 <210> 968 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 968 gatcgcttct ctggctccaa gtctggcaac acggcctgcc tgaccatctc tgggctccag 60 gctgaggatg atgctgatta ttactgctgc tcatatgcag gcagctacac tttcgcggtg 120 ttcggcgga 129 <210> 969 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 969 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Cys Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Asp Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Val Phe Gly Gly 35 40 <210> 970 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 970 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgtgctccag 60 gctgaggatg atgctgatta ttactgctgc tcatatgcag gcagctacac tttcgcggtg 120 ttcggcgga 129 <210> 971 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 971 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Val Leu Gln Ala Glu Asp Asp Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Val Phe Gly Gly 35 40 <210> 972 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 972 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcggtg 120 ttcggcgga 129 <210> 973 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 973 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Val Phe Gly Gly 35 40 <210> 974 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 974 gatcgcttct ctggctccaa ggctcgcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcggtg 120 ttcggcgga 129 <210> 975 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 975 Asp Arg Phe Ser Gly Ser Lys Ala Arg Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Val Phe Gly Gly 35 40 <210> 976 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 976 gatcgcttcc ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccgg 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcggtg 120 ttcggcgga 129 <210> 977 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 977 Asp Arg Phe Pro Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Arg Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Val Phe Gly Gly 35 40 <210> 978 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 978 ttacgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcggtg 120 ttcggcgga 129 <210> 979 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 979 Leu Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Val Phe Gly Gly 35 40 <210> 980 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 980 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcggtg 120 ttcggcgga 129 <210> 981 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 981 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Val Phe Gly Gly 35 40 <210> 982 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 982 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Asp Val Val Phe 1 5 10 <210> 983 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 983 cgcttctctg gctgcaagtc tggcaacacg gcctccctga ccatctctgg gctgcaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cgatgtggta 120 ttcggcgga 129 <210> 984 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 984 Arg Phe Ser Gly Cys Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 985 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 985 cgcttctctg gctcgatgtc tggcaacacg gcctccctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cgatgtggta 120 ttcggcgga 129 <210> 986 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 986 Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 987 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 987 cgcttctctg gctccaagtc tgtcaacatg gcctccctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cgatgtggta 120 ttcggcgga 129 <210> 988 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 988 Arg Phe Ser Gly Ser Lys Ser Val Asn Met Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 989 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 989 cgcttctctg gctccaagtc tgtcaacacg gcctccctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cgatgttgta 120 ttcggcgga 129 <210> 990 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 990 Arg Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 991 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 991 cgcttctctg gctccaagtc tggcaactcg gcctccctga ccatctctgg gctcgaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cgatgtggta 120 ttcggcgga 129 <210> 992 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 992 Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 993 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 993 cgcttctctg gctccaagtc tggcaacacg gcctccctgg ccatctctgg gctccaggct 60 gaggataagg ctgattatta ctgctgctca tatgcaggca gctacacttt cgatgtggta 120 ttcggcgga 129 <210> 994 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 994 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Lys Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 995 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 995 cgcttctctg gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cgatgtggta 120 ttcggcgga 129 <210> 996 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 996 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 997 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 997 cgcttctctg gctccaagtc cggcaacacg gcctccctga ctatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cgatgtggta 120 ttcggcgga 129 <210> 998 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 998 tcgcttctct ggctccaagt ctggcaacac ggcctcctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cgatgtggta 120 ttcggcgga 129 <210> 999 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 999 Ser Leu Leu Trp Leu Gln Val Trp Gln His Gly Leu Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 1000 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1000 tcgcttctct ggctccaagt ctggcaacac ggcctccctg accatctctg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cgatgtggta 120 ttcggcgga 129 <210> 1001 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1001 Ser Leu Leu Trp Leu Gln Val Trp Gln His Gly Leu Pro Asp His Leu 1 5 10 15 Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 1002 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1002 Cys Ser Tyr Ala Gly Ser Ser Thr Leu Phe 1 5 10 <210> 1003 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1003 tttctaatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacttta 120 ttcggcgga 129 <210> 1004 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1004 Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Leu Phe Gly Gly 35 40 <210> 1005 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1005 gtttctaatc tcttctctgg ctccaagtct tgcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacttta 120 ttcggcgga 129 <210> 1006 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1006 Val Ser Asn Leu Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Leu Phe Gly Gly 35 40 <210> 1007 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1007 gtttctaatc gcttctctgt ctccaagtct ggaaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacttta 120 ttcggcgga 129 <210> 1008 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1008 Val Ser Asn Arg Phe Ser Val Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Leu Phe Gly Gly 35 40 <210> 1009 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1009 gtttctaatc gcttctctgg ctccaagtct tgcatcacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacttta 120 ttcggcgga 129 <210> 1010 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1010 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Cys Ile Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Leu Phe Gly Gly 35 40 <210> 1011 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1011 gtttctaatc gcttctctgg ctccaagtct ggcaagactg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacttta 120 ttcggcgga 129 <210> 1012 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1012 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Leu Phe Gly Gly 35 40 <210> 1013 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1013 gtttctaatc gcttctctgg ctccaagtct ggcaacactg cctccctgac aatctctcgg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacttta 120 ttcggcgga 129 <210> 1014 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1014 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Arg Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Leu Phe Gly Gly 35 40 <210> 1015 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1015 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctgtg 60 ctccaggctg atgacgaggc tgattattac tgctgctcat atgcaggtag tagcacttta 120 ttcggcgga 129 <210> 1016 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1016 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Val Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Leu Phe Gly Gly 35 40 <210> 1017 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1017 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacttta 120 ttcggcgga 129 <210> 1018 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1018 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Leu Phe Gly Gly 35 40 <210> 1019 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1019 gtttctaatc gcttctctgg ctccaagtcc ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgatcattac tgctgctcat atgcaggtag tagcacttta 120 ttcggcgga 129 <210> 1020 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1020 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp His Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Leu Phe Gly Gly 35 40 <210> 1021 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1021 gttcttattc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacttta 120 ttcggcgga 129 <210> 1022 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1022 Val Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Leu Phe Gly Gly 35 40 <210> 1023 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1023 Cys Ser Tyr Ala Gly Ser Ser Ser Tyr Val Phe 1 5 10 <210> 1024 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1024 tctcatcgct tctctggctc caaggctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttatgtc 120 ttcggaact 129 <210> 1025 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1025 Ser His Arg Phe Ser Gly Ser Lys Ala Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Tyr Val Phe Gly Thr 35 40 <210> 1026 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1026 tctaatcgct tctctggctc caagtctggc atcacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttatgtc 120 ttcggaact 129 <210> 1027 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1027 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Tyr Val Phe Gly Thr 35 40 <210> 1028 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1028 tctaatcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctctgggctc 60 cagtctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttatgtc 120 ttcggaact 129 <210> 1029 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1029 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Tyr Val Phe Gly Thr 35 40 <210> 1030 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1030 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttatgtc 120 ttcggaact 129 <210> 1031 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1031 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Tyr Val Phe Gly Thr 35 40 <210> 1032 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1032 tctaatcgct tctctggctc caagtctggc aacacggcct gcctgtcaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttatgtc 120 ttcggaact 129 <210> 1033 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1033 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Cys Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Tyr Val Phe Gly Thr 35 40 <210> 1034 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1034 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttatgtc 120 ttcggaact 129 <210> 1035 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1035 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Tyr Val Phe Gly Thr 35 40 <210> 1036 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1036 tctaatcgct tctctggctc caaggctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgatgctga ttattactgc tgctcatatg caggtagtag ctcttatgtc 120 ttcggaact 129 <210> 1037 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1037 Ser Asn Arg Phe Ser Gly Ser Lys Ala Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Asp Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Tyr Val Phe Gly Thr 35 40 <210> 1038 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1038 tctaatcgct tccctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgggg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttatgtc 120 ttcggaact 129 <210> 1039 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1039 Ser Asn Arg Phe Pro Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Gly Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Tyr Val Phe Gly Thr 35 40 <210> 1040 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1040 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttatgtc 120 ttcggaact 129 <210> 1041 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1041 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Tyr Val Phe Gly Thr 35 40 <210> 1042 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1042 ctaatacgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttatgtc 120 ttcggaact 129 <210> 1043 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1043 Cys Ser Tyr Ala Gly Ser Tyr Thr Ser Val Val Phe 1 5 10 <210> 1044 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1044 gatcgcttct ctggctccaa gtctggcatc tcggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttccgtggta 120 ttcggcgga 129 <210> 1045 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1045 Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Val Val Phe Gly Gly 35 40 <210> 1046 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1046 gatcgcttct ctggctccaa gtctggcatc acggcctccc tgaccttctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttccgtggta 120 ttcggcgga 129 <210> 1047 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1047 Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr Phe 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Val Val Phe Gly Gly 35 40 <210> 1048 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1048 gatcgcttct ctggctccaa gtctggcaac acggcctccc ttaccatctc tgggctccag 60 gctgaggatg tggctgatta ttactgctgc tcatatgcag gcagctacac ttccgtggta 120 ttcggcgga 129 <210> 1049 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1049 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Val Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Val Val Phe Gly Gly 35 40 <210> 1050 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1050 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctcctg 60 gctgaggttg aggctgatta ttactgctgc tcatatgcag gcagctacac ttccgtggta 120 ttcggcgga 129 <210> 1051 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1051 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Leu Ala Glu Val Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Val Val Phe Gly Gly 35 40 <210> 1052 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1052 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctcctg 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttccgttgta 120 ttcggcgga 129 <210> 1053 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1053 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Val Val Phe Gly Gly 35 40 <210> 1054 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1054 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg agtctgatta ttactgctgc tcatatgcag gcagctacac ttccgttgta 120 ttcggcgga 129 <210> 1055 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1055 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Val Val Phe Gly Gly 35 40 <210> 1056 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1056 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttccgtggta 120 ttcggcgga 129 <210> 1057 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1057 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Val Val Phe Gly Gly 35 40 <210> 1058 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1058 tttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttccgtggta 120 ttcggcgga 129 <210> 1059 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1059 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Val Val Phe Gly Gly 35 40 <210> 1060 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1060 ttccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttccgtggta 120 ttcggcgga 129 <210> 1061 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1061 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttccgtggta 120 ttcggcgga 129 <210> 1062 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1062 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Val Val Phe Gly Gly 35 40 <210> 1063 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1063 Cys Ser Tyr Ala Gly Ser Tyr Thr Val Val Phe 1 5 10 <210> 1064 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1064 ctgattcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactgtggta 120 ttcggcgga 129 <210> 1065 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1065 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 1066 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1066 cgtgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 ctggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactgtggta 120 ttcggcgga 129 <210> 1067 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1067 Arg Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 1068 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1068 cctgatggct tctctggctc caagtctggc aacacggcct ccctgacctt ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactgtggta 120 ttcggcgga 129 <210> 1069 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1069 Pro Asp Gly Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 1070 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1070 cctgatcgct tctctggctc caagtctggc tactcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactgtggta 120 ttcggcgga 129 <210> 1071 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1071 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 1072 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1072 cctgatcgct tctctggctc caagtctggc tacacggcct ccctgacgat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactgtggta 120 ttcggcgga 129 <210> 1073 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1073 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 1074 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1074 cctgatcgct tctctggctc caagtctggc aactcggcct ccctgaccat ctctgggctc 60 cagtctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactgtggta 120 ttcggcgga 129 <210> 1075 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1075 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 1076 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1076 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 cagtctgagg atgagtctga ttattactgc tgctcatatg caggcagcta cactgtggta 120 ttcggcgga 129 <210> 1077 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1077 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 1078 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1078 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactgtggta 120 ttcggcgga 129 <210> 1079 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1079 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 1080 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1080 cctgatcgct tctctggctc caagtctgga aacacggcct ccctgaccat ctctgggctc 60 ctggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactgtggta 120 ttcggcgga 129 <210> 1081 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1081 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 1082 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1082 cctgatcgct tccctggctc caagtctggc aacacggcct ccctgaccac ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactgtggta 120 ttcggcgga 129 <210> 1083 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1083 Pro Asp Arg Phe Pro Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Thr Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 1084 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1084 Cys Ser Tyr Ala Gly Ser Tyr Thr Asn Trp Val Phe 1 5 10 <210> 1085 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1085 gatcgcttct ctgtctccaa gtctgtcaac acggcctccc tgaccctctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac caattgggtg 120 ttcggcgga 129 <210> 1086 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1086 Asp Arg Phe Ser Val Ser Lys Ser Val Asn Thr Ala Ser Leu Thr Leu 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Asn Trp Val Phe Gly Gly 35 40 <210> 1087 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1087 gatcgcttct ctggctcgaa gtctggcaac actgcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac caattgggtg 120 ttcggcgga 129 <210> 1088 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1088 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Asn Trp Val Phe Gly Gly 35 40 <210> 1089 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1089 gatcgcttct ctggctccaa gtctggcaag acggcctccc tgtccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac caattgggtg 120 ttcggcgga 129 <210> 1090 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1090 Asp Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Asn Trp Val Phe Gly Gly 35 40 <210> 1091 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1091 gatcgcttct ctggctccaa gtctggcaac actgcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac caattgggtg 120 ttcggcggt 129 <210> 1092 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1092 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac caattgggtg 120 ttcggcgga 129 <210> 1093 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1093 gatcgcttct cgggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gcagctacac caattgggtg 120 ttcggcgga 129 <210> 1094 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1094 ttccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac caattgggtg 120 ttcggcgga 129 <210> 1095 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1095 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Asn Trp Val Phe Gly Gly 35 40 <210> 1096 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1096 gttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac caattgggtg 120 ttcggcgga 129 <210> 1097 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1097 Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Asn Trp Val Phe Gly Gly 35 40 <210> 1098 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1098 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac caattgggtg 120 ttcggcgga 129 <210> 1099 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1099 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Asn Trp Val Phe Gly Gly 35 40 <210> 1100 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1100 Cys Ser Tyr Ala Gly Ser Ser Thr Pro Tyr Val Phe 1 5 10 <210> 1101 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1101 tttcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tccctacgtc 120 ttcggaact 129 <210> 1102 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1102 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Tyr Val Phe Gly Thr 35 40 <210> 1103 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1103 aatcgcttct ctggctccat gtctggcatc acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tccttatgtc 120 ttcggaact 129 <210> 1104 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1104 Asn Arg Phe Ser Gly Ser Met Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Tyr Val Phe Gly Thr 35 40 <210> 1105 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1105 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctcgag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tccttatgtc 120 ttcggatct 129 <210> 1106 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1106 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Tyr Val Phe Gly Ser 35 40 <210> 1107 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1107 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tccttatgtc 120 ttcggaact 129 <210> 1108 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1108 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Tyr Val Phe Gly Thr 35 40 <210> 1109 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1109 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tccctacgtc 120 ttcggaact 129 <210> 1110 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1110 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac cccctatgtc 120 ttcggaact 129 <210> 1111 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1111 aatcgattct ctggctccaa gtctggcaac acggcctccc tgactatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tccctacgtc 120 ttcggaact 129 <210> 1112 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1112 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tccttatgtc 120 ttcggaact 129 <210> 1113 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1113 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Pro Tyr Val Phe Gly Thr 35 40 <210> 1114 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1114 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac cccctatgtc 120 ttcggaact 129 <210> 1115 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1115 Cys Ser Tyr Ala Gly Ser Val Val Phe 1 5 <210> 1116 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1116 ggggttctaa ttcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtgtggta 120 ttcggcgga 129 <210> 1117 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1117 Gly Val Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Gly Gly 35 40 <210> 1118 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1118 ggggttctaa tccgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtgtggta 120 ttcggcgga 129 <210> 1119 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1119 gggtttctaa tccgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtgtggta 120 ttcggcgga 129 <210> 1120 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1120 Gly Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Gly Gly 35 40 <210> 1121 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1121 gtggtttcta atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgatgacga ggctgattat tactgctgct catatgcagg tagtgtggta 120 ttcggcgga 129 <210> 1122 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1122 Val Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Gly Gly 35 40 <210> 1123 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1123 ggtgtttcta atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 tggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtgtggta 120 ttcggcgga 129 <210> 1124 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1124 Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Gly Gly 35 40 <210> 1125 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1125 ggggtttcta atcgcttctc ttgctcgaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtgtggta 120 ttcggcgga 129 <210> 1126 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1126 Gly Val Ser Asn Arg Phe Ser Cys Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Gly Gly 35 40 <210> 1127 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1127 ggggtttcta atcgcttctc ttgctccaag tctggcaaca cggcctccct gagaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtgtggta 120 ttcggcgga 129 <210> 1128 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1128 Gly Val Ser Asn Arg Phe Ser Cys Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Arg Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Gly Gly 35 40 <210> 1129 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1129 ggggtttcta atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtgtggta 120 ttcggcgga 129 <210> 1130 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1130 Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Gly Gly 35 40 <210> 1131 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1131 ggggttgcta atcgcttctc tggctcgaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtgtggta 120 ttcggcgga 129 <210> 1132 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1132 Gly Val Ala Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Gly Gly 35 40 <210> 1133 <211> 5 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1133 Cys Ser Glu Val Phe 1 5 <210> 1134 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1134 atgcggccct ctggggtttc ttatcgcttc tctggctcca agtctggcaa cacggcctcc 60 ctgacaatct ctgggctcca ggctgaggac gaggctgatt attactgctg ctcagaggta 120 ttcggcgga 129 <210> 1135 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1135 Met Arg Pro Ser Gly Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly 1 5 10 15 Asn Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala 20 25 30 Asp Tyr Tyr Cys Cys Ser Glu Val Phe Gly Gly 35 40 <210> 1136 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1136 aagcggccgt caggggtttc taatggcttc tctggctcca agtctggcaa cacggcctcc 60 ctgacaatct ctgggctcca ggctgaggac gaggctgatt attactgctg ctcagaggta 120 ttcggcgga 129 <210> 1137 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1137 Lys Arg Pro Ser Gly Val Ser Asn Gly Phe Ser Gly Ser Lys Ser Gly 1 5 10 15 Asn Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala 20 25 30 Asp Tyr Tyr Cys Cys Ser Glu Val Phe Gly Gly 35 40 <210> 1138 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1138 aagcggccct cagtggtttc taatcgcttc tctggctcca agtctggcaa gacggcctcc 60 ctgacaatct ctgggctcca ggctgaggac gaggctgatt attactgctg ctcagaggta 120 ttcggcgga 129 <210> 1139 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1139 Lys Arg Pro Ser Val Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly 1 5 10 15 Lys Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala 20 25 30 Asp Tyr Tyr Cys Cys Ser Glu Val Phe Gly Gly 35 40 <210> 1140 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1140 aagcggccct cagtggtttc taatcgcttc tctggctcca agtctggcaa cacgtcctcc 60 ctgacaatct ctgggctcca ggctgaggac gaggctgatt attactgctg ctcagaggta 120 ttcggcgga 129 <210> 1141 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1141 Lys Arg Pro Ser Val Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly 1 5 10 15 Asn Thr Ser Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala 20 25 30 Asp Tyr Tyr Cys Cys Ser Glu Val Phe Gly Gly 35 40 <210> 1142 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1142 aagcggccct cagtggtttc taatcgcttc tctggctcca agtctggcaa cacggcctcc 60 ctgacattct ctgggctcca ggctgaggac gaggctgatt attactgctg ctcagaggta 120 ttcggcgga 129 <210> 1143 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1143 Lys Arg Pro Ser Val Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly 1 5 10 15 Asn Thr Ala Ser Leu Thr Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala 20 25 30 Asp Tyr Tyr Cys Cys Ser Glu Val Phe Gly Gly 35 40 <210> 1144 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1144 aagcggccct caggggtttc ttatcgcttc tctggctcca agtctggcaa cacggcctcc 60 ctgactatct ctgggctcca ggctgaggac gaggctgatt attactgctg ctcagaggta 120 ttcggcgga 129 <210> 1145 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1145 Lys Arg Pro Ser Gly Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly 1 5 10 15 Asn Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala 20 25 30 Asp Tyr Tyr Cys Cys Ser Glu Val Phe Gly Gly 35 40 <210> 1146 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1146 aagcggccct caggggtttc taatcgcttc tctggctcca agtctggcaa cacggcctcc 60 ctgacaatct ctgggctcca ggctgaggac gaggctgatt attactgctg ctcagaggta 120 ttcggcgga 129 <210> 1147 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1147 Lys Arg Pro Ser Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly 1 5 10 15 Asn Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala 20 25 30 Asp Tyr Tyr Cys Cys Ser Glu Val Phe Gly Gly 35 40 <210> 1148 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1148 aagcggccct caggggtttc taatcgcttc tctggctcca agtctggcaa cacggcctcc 60 ctgacaatct ctgggctaca ggctgaggac gaggctggtt attactgctg ctcagaggta 120 ttcggcgga 129 <210> 1149 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1149 Lys Arg Pro Ser Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly 1 5 10 15 Asn Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala 20 25 30 Gly Tyr Tyr Cys Cys Ser Glu Val Phe Gly Gly 35 40 <210> 1150 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1150 aagcggccct caggggtttc taatcgcttc tctggccccg agtctggcaa cacggcctcc 60 ctgacaatct ctgggctcca ggctgaggac gaggctgatt attactgctg ctcagaggta 120 ttcggcgga 129 <210> 1151 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1151 Lys Arg Pro Ser Gly Val Ser Asn Arg Phe Ser Gly Pro Glu Ser Gly 1 5 10 15 Asn Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala 20 25 30 Asp Tyr Tyr Cys Cys Ser Glu Val Phe Gly Gly 35 40 <210> 1152 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1152 Cys Ser Tyr Ala Gly Ser Ser Thr Val Phe 1 5 10 <210> 1153 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1153 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacggggc tgattattac tgctgctcat atgcaggtag tagcacggta 120 ttcggcgga 129 <210> 1154 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1154 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Gly Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Val Phe Gly Gly 35 40 <210> 1155 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1155 tttctaatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacggta 120 ttcggcgga 129 <210> 1156 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1156 Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Val Phe Gly Gly 35 40 <210> 1157 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1157 gtttcttatc gcttctctgg ctccaagtct ggcatcacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacggta 120 ttcggcgga 129 <210> 1158 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1158 Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Val Phe Gly Gly 35 40 <210> 1159 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1159 gtttctattc gcttctctgg ctccaagtct gccaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacggta 120 ttcggcgga 129 <210> 1160 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1160 Val Ser Ile Arg Phe Ser Gly Ser Lys Ser Ala Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Val Phe Gly Gly 35 40 <210> 1161 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1161 gtttctaatc gcttctctgg ctcgaagtct ggctacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacggta 120 ttcggcgga 129 <210> 1162 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1162 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Val Phe Gly Gly 35 40 <210> 1163 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1163 gtttctaatc gcttctctgg ctccaagtct ggctacacgg cctccctgac attctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcactgta 120 ttcggcgga 129 <210> 1164 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1164 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu 1 5 10 15 Thr Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Val Phe Gly Gly 35 40 <210> 1165 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1165 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcactgta 120 ttcggcgga 129 <210> 1166 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1166 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Val Phe Gly Gly 35 40 <210> 1167 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1167 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcacggta 120 ttcggcgga 129 <210> 1168 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1168 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgatatttac tgctgctcat atgcaggtag tagcacggta 120 ttcggcgga 129 <210> 1169 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1169 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Ile Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Val Phe Gly Gly 35 40 <210> 1170 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1170 Cys Ser Phe Ala Gly Gly Gly Thr Trp Gly Phe 1 5 10 <210> 1171 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1171 tcttatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgtgctc 60 caggctgagg acgaggctga ttattattgc tgctcatttg caggtggtgg gacttggggg 120 ttcggcgga 129 <210> 1172 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1172 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Gly Gly Thr Trp Gly Phe Gly Gly 35 40 <210> 1173 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1173 tctcatcgct tctctggctc caagtctggc aacacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattattgc tgctcatttg caggtggtgg gacttggggg 120 ttcggcgga 129 <210> 1174 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1174 Ser His Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Gly Gly Thr Trp Gly Phe Gly Gly 35 40 <210> 1175 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1175 tctactcgct tctctggctc caaggctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattattgc tgctcatttg caggtggtgg gacttggggg 120 ttcggcgga 129 <210> 1176 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1176 Ser Thr Arg Phe Ser Gly Ser Lys Ala Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Gly Gly Thr Trp Gly Phe Gly Gly 35 40 <210> 1177 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1177 tctaatcgct tctctggctc catgtctggc aactcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattattgc tgctcatttg caggtggtgg gacttggggg 120 ttcggcgga 129 <210> 1178 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1178 Ser Asn Arg Phe Ser Gly Ser Met Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Gly Gly Thr Trp Gly Phe Gly Gly 35 40 <210> 1179 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1179 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattattgc tgctcatttg caggtggtgg gacttggggg 120 ttcggcgga 129 <210> 1180 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1180 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Gly Gly Thr Trp Gly Phe Gly Gly 35 40 <210> 1181 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1181 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga tatttattgc tgctcatttg caggtggtgg gacttggggg 120 ttcggcgga 129 <210> 1182 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1182 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Ile Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Gly Gly Thr Trp Gly Phe Gly Gly 35 40 <210> 1183 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1183 gctaatcgct tctctggctt caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattattgc tgctcatttg caggtggtgg gacttggggg 120 ttcggcgga 129 <210> 1184 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1184 Ala Asn Arg Phe Ser Gly Phe Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Gly Gly Thr Trp Gly Phe Gly Gly 35 40 <210> 1185 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1185 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattattgc tgctcatttg caggtggtgg gacttggggg 120 ttcggcgga 129 <210> 1186 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1186 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Gly Gly Thr Trp Gly Phe Gly Gly 35 40 <210> 1187 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1187 Cys Ser Tyr Ala Gly Ser Ser Thr Pro Asn Trp Val Phe 1 5 10 <210> 1188 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1188 cgcttgtctg gctccatgtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacgcc taattgggtg 120 ttcggcgga 129 <210> 1189 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1189 Arg Leu Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Asn Trp Val Phe Gly Gly 35 40 <210> 1190 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1190 cgcttctctg gctccatgtc tggctacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacgcc taattgggtg 120 ttcggcgga 129 <210> 1191 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1191 Arg Phe Ser Gly Ser Met Ser Gly Tyr Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Asn Trp Val Phe Gly Gly 35 40 <210> 1192 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1192 cgcttctctg gctccaagtc tggcatctcg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacgcc taattgggtg 120 ttcggcgga 129 <210> 1193 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1193 Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Asn Trp Val Phe Gly Gly 35 40 <210> 1194 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1194 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacgcc taattgggtg 120 ttcggcgga 129 <210> 1195 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1195 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Asn Trp Val Phe Gly Gly 35 40 <210> 1196 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1196 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctcg gctccaggct 60 gatgacgagg ctgattatta ctgctgctca tatgcaggta gtagcacgcc taattgggtg 120 ttcggcgga 129 <210> 1197 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1197 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Arg Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Asn Trp Val Phe Gly Gly 35 40 <210> 1198 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1198 cgcttctctg gctccaagtc tggcaacacg gcctccctga caacctctgg gctccaggct 60 aaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacgcc taattgggtg 120 ttcggcgga 129 <210> 1199 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1199 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Thr Ser 1 5 10 15 Gly Leu Gln Ala Lys Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Asn Trp Val Phe Gly Gly 35 40 <210> 1200 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1200 cgctgctctg gctccaaggc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacgcc taattgggtg 120 ttcggcgga 129 <210> 1201 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1201 Arg Cys Ser Gly Ser Lys Ala Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Asn Trp Val Phe Gly Gly 35 40 <210> 1202 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1202 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccgggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacgcc taattgggtg 120 ttcggcgga 129 <210> 1203 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1203 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Arg Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Asn Trp Val Phe Gly Gly 35 40 <210> 1204 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1204 Cys Ser Tyr Ala Gly Ser Gly Ile Phe Tyr Val Phe 1 5 10 <210> 1205 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1205 attcgcttct ctggctccaa gtctggcatc tcggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtggaat tttttatgtc 120 ttcggaact 129 <210> 1206 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1206 Ile Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Gly Ile Phe Tyr Val Phe Gly Thr 35 40 <210> 1207 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1207 actcgcttct ctggctccaa gtctggcaac acggcctccc tgactatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtggaat tttttatgtc 120 ttcggaact 129 <210> 1208 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1208 Thr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Gly Ile Phe Tyr Val Phe Gly Thr 35 40 <210> 1209 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1209 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtggaat tttttatgtc 120 ttcggaact 129 <210> 1210 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1210 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Gly Ile Phe Tyr Val Phe Gly Thr 35 40 <210> 1211 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1211 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtggaat tttttacgtc 120 tttggaact 129 <210> 1212 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1212 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggccccag 60 gctgaggacg aggccgatta ttactgctgc tcatatgcag gtagtggaat tttttatgtc 120 ttcggaact 129 <210> 1213 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1213 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Pro Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Gly Ile Phe Tyr Val Phe Gly Thr 35 40 <210> 1214 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1214 aatcgcttct ctggctccaa gtctagcaac acggcctccc tgacaatccc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtggaat tttttatgtc 120 ttcggaact 129 <210> 1215 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1215 Asn Arg Phe Ser Gly Ser Lys Ser Ser Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Pro Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Gly Ile Phe Tyr Val Phe Gly Thr 35 40 <210> 1216 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1216 aatcgcttct ctggctccaa gtcaggcaac acggcctccc tgactatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtggaat tttttatgtc 120 ttcggaact 129 <210> 1217 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1217 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtggaat tttttatgtc 120 ttcggaact 129 <210> 1218 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1218 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Gly Ile Phe Tyr Val Phe Gly Thr 35 40 <210> 1219 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1219 Cys Ser Tyr Ala Gly Ser His Ser Tyr Val Phe 1 5 10 <210> 1220 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1220 ccctatcgct tctctggctc caagtctggc gacacggcct ccctgaccat ctctgggctc 60 cagcctgacg atgaggctga ctatcactgc tgctcatatg caggcagcca tagttatgtt 120 ttcggatct 129 <210> 1221 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1221 Pro Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asp Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Pro Asp Asp Glu Ala Asp Tyr His Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Ser Tyr Val Phe Gly Ser 35 40 <210> 1222 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1222 ctaatccgct tctctggctc caagtctggc gacacggcct ccctgaccat ctctgggctc 60 cagcctgacg atgaggctga ctatcactgc tgctcatatg caggcagcca tagttatgtt 120 ttcggatct 129 <210> 1223 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1223 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asp Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Pro Asp Asp Glu Ala Asp Tyr His Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Ser Tyr Val Phe Gly Ser 35 40 <210> 1224 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1224 cgtaatcgct tctctggctc caagtctggc gacacggcct ccctgaccat ctctgggctc 60 cagcccgacg atgaggctga ctatcactgc tgctcatatg caggcagcca tagttatgtt 120 ttcggatct 129 <210> 1225 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1225 Arg Asn Arg Phe Ser Gly Ser Lys Ser Gly Asp Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Pro Asp Asp Glu Ala Asp Tyr His Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Ser Tyr Val Phe Gly Ser 35 40 <210> 1226 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1226 cctaatcgct tctctggctc gatgtctggc gacacggcct ccctgaccat ctctgggctc 60 cagcctgacg atgaggctga ctatcactgc tgctcatatg caggcagcca tagttatgtt 120 ttcggatct 129 <210> 1227 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1227 Pro Asn Arg Phe Ser Gly Ser Met Ser Gly Asp Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Pro Asp Asp Glu Ala Asp Tyr His Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Ser Tyr Val Phe Gly Ser 35 40 <210> 1228 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1228 cctaatcgct tctctggctc catgtctggc gacacggcct ccctgaccat ctctgggctc 60 cagcctgacg atgaggctaa ctatcactgc tgctcatatg caggcagcca tagttatgtt 120 ttcggatct 129 <210> 1229 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1229 Pro Asn Arg Phe Ser Gly Ser Met Ser Gly Asp Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Pro Asp Asp Glu Ala Asn Tyr His Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Ser Tyr Val Phe Gly Ser 35 40 <210> 1230 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1230 cctaatcgct tctctggctc caagtctggc gtcacggcct ccctgaccat ctctgggctc 60 ctgcctgacg atgaggctga ctatcactgc tgctcatatg caggcagcca tagttatgtt 120 ttcggatct 129 <210> 1231 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1231 Pro Asn Arg Phe Ser Gly Ser Lys Ser Gly Val Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Leu Pro Asp Asp Glu Ala Asp Tyr His Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Ser Tyr Val Phe Gly Ser 35 40 <210> 1232 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1232 cctaatcgct tctctggctc caagtctggc gacacggcct ccctgaccat ctctgggctc 60 cagcctgacg atgaggctga ctatcactgc tgctcatatg caggcagcca tagttatgtt 120 ttcggatct 129 <210> 1233 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1233 Pro Asn Arg Phe Ser Gly Ser Lys Ser Gly Asp Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Pro Asp Asp Glu Ala Asp Tyr His Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Ser Tyr Val Phe Gly Ser 35 40 <210> 1234 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1234 cctaatcgct tctctggctc caagtctggc gacactgcct ccctgaccat ctctgggctc 60 cagcctgacg atgaggctga ctatcactgc tgctcatatg caggcagcca tagttatgtt 120 ttcggatct 129 <210> 1235 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1235 Cys Ser Tyr Thr Ser Ser Ala Thr Trp Val Phe 1 5 10 <210> 1236 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1236 cctggtcgtc tctctggttc caagtctggc aacacggcct ccatgaccat ctctggactc 60 caggctgagg acgaggctga ttattactgc tgctcatata caagcagtgc cacttgggtg 120 ttcggcgga 129 <210> 1237 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1237 Pro Gly Arg Leu Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Met Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Ser Ser Ala Thr Trp Val Phe Gly Gly 35 40 <210> 1238 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1238 cctgatcgtc tctctggttt cgagtctggc aatacggcct ccatgaccat ctctggactc 60 caggctgagg acgaggctga ttattactgc tgctcatata caagcagtgc cacttgggtg 120 ttcggcgga 129 <210> 1239 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1239 Pro Asp Arg Leu Ser Gly Phe Glu Ser Gly Asn Thr Ala Ser Met Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Ser Ser Ala Thr Trp Val Phe Gly Gly 35 40 <210> 1240 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1240 cctgatcgtc tctctggttc gaagtctggc aatactgcct ccatgaccat ctctggactc 60 caggctgagg acgaggctga ttattactgc tgctcatata caagcagtgc cacttgggtg 120 ttcggcgga 129 <210> 1241 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1241 Pro Asp Arg Leu Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Met Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Ser Ser Ala Thr Trp Val Phe Gly Gly 35 40 <210> 1242 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1242 cctgatcgtc tctctggttc caagtctggc attacggcct ccatgaccat ctctggactc 60 cagtctgagg acgaggctga ttattactgc tgctcatata caagcagtgc cacttgggtg 120 ttcggcgga 129 <210> 1243 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1243 Pro Asp Arg Leu Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Met Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Ser Ser Ala Thr Trp Val Phe Gly Gly 35 40 <210> 1244 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1244 cctgatcgtc tctctggttc caagtctggc aatacggcct ccatgaccat ctctggactc 60 caggctgagg acgaggctga ttattactgc tgctcatata caagcagtgc cacttgggtg 120 ttcggcgga 129 <210> 1245 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1245 cctgatcgtc tctctggttc caagtctggc aatacggact ccatgaccat ctctggactc 60 caggctgatg acgaggctga ttattactgc tgctcatata caagcagtgc cacttgggtg 120 ttcggcgga 129 <210> 1246 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1246 Pro Asp Arg Leu Ser Gly Ser Lys Ser Gly Asn Thr Asp Ser Met Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Ser Ser Ala Thr Trp Val Phe Gly Gly 35 40 <210> 1247 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1247 cctgatcgtc tctctggttc caagtccggc aatacggcct ccatgaccat ctctggaccc 60 caggctgagg acgaggctga ttattactgc tgctcatata caagcagtgc cacttgggtg 120 ttcggcgga 129 <210> 1248 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1248 Pro Asp Arg Leu Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Met Thr 1 5 10 15 Ile Ser Gly Pro Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Ser Ser Ala Thr Trp Val Phe Gly Gly 35 40 <210> 1249 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1249 cctgatcgtc tctctggttc caagtctggc attacggcct ccatgaccat ctctggactc 60 caggctgagg acgaggctga ttattactgc tgctcatata caagcagtgc cacttgggtg 120 ttcggcgga 129 <210> 1250 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1250 Pro Asp Arg Leu Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Met Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Ser Ser Ala Thr Trp Val Phe Gly Gly 35 40 <210> 1251 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1251 Cys Ser Tyr Ala Gly Gly Ser Thr Val Val Phe 1 5 10 <210> 1252 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1252 tctattcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg tcgaggctga ttattactgc tgctcatatg caggtggaag cactgtggta 120 ttcggcgga 129 <210> 1253 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1253 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Val Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Gly Ser Thr Val Val Phe Gly Gly 35 40 <210> 1254 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1254 tctaatcgct tctctggctc caagtctggg agctcggcct ccctgacagt ctctgggctc 60 caggctgagg acgagggtga ctattactgc tgctcatatg caggtggtag tactgtggtg 120 ttcggcgga 129 <210> 1255 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1255 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ser Ser Ala Ser Leu Thr 1 5 10 15 Val Ser Gly Leu Gln Ala Glu Asp Glu Gly Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Gly Ser Thr Val Val Phe Gly Gly 35 40 <210> 1256 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1256 tctaatcgct tctctggctc caagtctggc agctcggcct cgctgacagt ctctgggctc 60 caggctgagg acgagggtga ctattactgc tgctcatatg caggtggtag tactgtggtg 120 ttcggcgga 129 <210> 1257 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1257 tctaatcgct tctctggctc caagtctggc agcacggcct ccctgacagt ctctgtgctc 60 caggctgagg acgagggtga ctatttctgc tgctcatatg caggtggtag tactgtggtg 120 ttcggcgga 129 <210> 1258 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1258 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ser Thr Ala Ser Leu Thr 1 5 10 15 Val Ser Val Leu Gln Ala Glu Asp Glu Gly Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ala Gly Gly Ser Thr Val Val Phe Gly Gly 35 40 <210> 1259 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1259 tctaatcgct tctctggctc caagtctggc agcacggcct ccctgacagt ctctgggctc 60 caggctgagg acgagggtga ctattactgc tgctcatatg caggtggtag tactgtggtg 120 ttcggcgga 129 <210> 1260 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1260 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ser Thr Ala Ser Leu Thr 1 5 10 15 Val Ser Gly Leu Gln Ala Glu Asp Glu Gly Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Gly Ser Thr Val Val Phe Gly Gly 35 40 <210> 1261 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1261 tctaatcgct tctctggctc caagtctggc agcacggcct ccctgacagc ctcttggctc 60 caggctgagg acgagggtga ctattactgc tgctcatatg caggtggtag tactgtggtg 120 ttcggcgga 129 <210> 1262 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1262 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ser Thr Ala Ser Leu Thr 1 5 10 15 Ala Ser Trp Leu Gln Ala Glu Asp Glu Gly Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Gly Ser Thr Val Val Phe Gly Gly 35 40 <210> 1263 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1263 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtggtag cactgtggta 120 ttcggcgaa 129 <210> 1264 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1264 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Gly Ser Thr Val Val Phe Gly Glu 35 40 <210> 1265 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1265 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtggaag cactgtggta 120 ttcggcgga 129 <210> 1266 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1266 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Gly Ser Thr Val Val Phe Gly Gly 35 40 <210> 1267 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1267 Cys Ser Tyr Ala Gly Ser Ser Ser Val Val Phe 1 5 10 <210> 1268 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1268 tctaatcgct tctcttgctc caagtctggc aacacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctctgtggta 120 ttcggcgga 129 <210> 1269 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1269 Ser Asn Arg Phe Ser Cys Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Val Val Phe Gly Gly 35 40 <210> 1270 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1270 tctaatcgct tctctggctc caagtctggc tacacgggct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctctgtggta 120 ttcggcgga 129 <210> 1271 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1271 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Gly Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Val Val Phe Gly Gly 35 40 <210> 1272 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1272 tctaatcgct tctctggctc caagtctggc aacacgtcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctctgttgta 120 ttcggcgga 129 <210> 1273 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1273 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ser Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Val Val Phe Gly Gly 35 40 <210> 1274 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1274 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctctgtggta 120 ttcggcgga 129 <210> 1275 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1275 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Val Val Phe Gly Gly 35 40 <210> 1276 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1276 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cagtgtggta 120 ttcggcggt 129 <210> 1277 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1277 tctaatcgct tctctggctc caagcctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatacg caggtagtag ctctgtggta 120 ttcggcgga 129 <210> 1278 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1278 Ser Asn Arg Phe Ser Gly Ser Lys Pro Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Val Val Phe Gly Gly 35 40 <210> 1279 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1279 cttatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctctgtggta 120 ttcggcgga 129 <210> 1280 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1280 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Val Val Phe Gly Gly 35 40 <210> 1281 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1281 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctctgtggta 120 ttcggcgga 129 <210> 1282 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1282 Cys Ser Tyr Ala Gly Ser Arg Arg Val Phe 1 5 10 <210> 1283 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1283 tttctaatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagaagggtc 120 ttcggaact 129 <210> 1284 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1284 Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Arg Arg Val Phe Gly Thr 35 40 <210> 1285 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1285 gtttctaatg gcttctctgg ctcgaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagaagggtc 120 ttcggaact 129 <210> 1286 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1286 Val Ser Asn Gly Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Arg Arg Val Phe Gly Thr 35 40 <210> 1287 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1287 gtttctaatc gcttctctgg ctccaagtct ggctactcgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagaagggtc 120 ttcggaact 129 <210> 1288 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1288 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Ser Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Arg Arg Val Phe Gly Thr 35 40 <210> 1289 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1289 gtttctaatc gcttctctgg ctccaagtct ggcaactcgg cctccctgtc aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagaagggtc 120 ttcggaact 129 <210> 1290 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1290 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu 1 5 10 15 Ser Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Arg Arg Val Phe Gly Thr 35 40 <210> 1291 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1291 gtttctaatc gcttctctgg ctccaagtct ggcaacactg cctacctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagaagggtc 120 ttcggaact 129 <210> 1292 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1292 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Tyr Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Arg Arg Val Phe Gly Thr 35 40 <210> 1293 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1293 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagaagggtc 120 ttcggaact 129 <210> 1294 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1294 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Arg Arg Val Phe Gly Thr 35 40 <210> 1295 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1295 gtttataatc gcttctctgg ctccaagtct gtcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagaagggtc 120 ttcggaact 129 <210> 1296 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1296 Val Tyr Asn Arg Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Arg Arg Val Phe Gly Thr 35 40 <210> 1297 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1297 gcttctaata gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagaagggtc 120 ttcggaact 129 <210> 1298 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1298 Ala Ser Asn Ser Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Arg Arg Val Phe Gly Thr 35 40 <210> 1299 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1299 tctgatggct tctctggctc caagtctggc aactcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcgtatg caggtagttc cactttggtg 120 ttcggcgga 129 <210> 1300 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1300 Ser Asp Gly Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1301 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1301 tctgatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcgtatg caggtagttc cactttggtg 120 ttcggcgga 129 <210> 1302 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1302 Ser Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1303 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1303 tctaatcgct tctctggctc caagtctggc tacacggcct cgctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggtg 120 ttcggcgga 129 <210> 1304 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1304 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1305 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1305 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgactat ctctgggctc 60 cagtctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggtg 120 ttcggcgga 129 <210> 1306 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1306 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggtg 120 ttcggcgga 129 <210> 1307 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1307 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctccgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagcag cactttggtg 120 ttcggcgga 129 <210> 1308 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1308 ctgatccgct tctctggctc caagtctggc aacacggcct ccctggcaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcgtatg caggtagttc cactttggtg 120 ttcggcgga 129 <210> 1309 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1309 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1310 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1310 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggtg 120 ttcggcgga 129 <210> 1311 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1311 Cys Ser Tyr Ala Gly Ser Ser Thr Leu Leu Phe 1 5 10 <210> 1312 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1312 tctaatcgct tctctggctc ccactctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttatttctgc tgctcatatg caggtagtag cactttgcta 120 ttcggcgga 129 <210> 1313 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1313 Ser Asn Arg Phe Ser Gly Ser His Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Leu Phe Gly Gly 35 40 <210> 1314 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1314 tctaatcgct tctctggctc caagtctggc aagactgcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttatttctgc tgctcatatg caggtagtag cactttgcta 120 ttcggcgga 129 <210> 1315 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1315 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Leu Phe Gly Gly 35 40 <210> 1316 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1316 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttatttctgc tgctcatatg caggtagtag cactttgcta 120 ttcggcgga 129 <210> 1317 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1317 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Leu Phe Gly Gly 35 40 <210> 1318 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1318 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttatttctgc tgctcatacg caggtagtag cactttgcta 120 ttcgccgga 129 <210> 1319 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1319 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Leu Phe Ala Gly 35 40 <210> 1320 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1320 tctaatcgca tctctggctc gaagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttatttctgc tgctcatatg caggtagtag cactttgcta 120 ttcggcgga 129 <210> 1321 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1321 Ser Asn Arg Ile Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Leu Phe Gly Gly 35 40 <210> 1322 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1322 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttatttctgc tgctcatatg caggtagtag cactttgcta 120 ttcggcgga 129 <210> 1323 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1323 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Leu Phe Gly Gly 35 40 <210> 1324 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1324 ctaatacgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttatttctgc tgctcatatg caggtagtag cactttgcta 120 ttcggcgga 129 <210> 1325 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1325 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttatttctgc tgctcatatg caggtagcag cactttgcta 120 ttcggcgga 129 <210> 1326 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1326 Cys Ser Tyr Ala Gly Thr Tyr Ser Val Val Phe 1 5 10 <210> 1327 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1327 cctggtcggt tttctggctc caagtctggc aacacggcct ccctgaccat ctctggactc 60 cagcctgagg atgaacctga ttattactgc tgctcatatg caggcactta cagtgttgta 120 ttcggcgga 129 <210> 1328 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1328 Pro Gly Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Pro Glu Asp Glu Pro Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Ser Val Val Phe Gly Gly 35 40 <210> 1329 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1329 cctgatcggt tttctggctc caagtctggc atcacggcct ccctgaccat gtctggactc 60 cagcctgagg atgaatctga ttattactgc tgctcatatg caggcactta cagtgttgta 120 ttcggcgga 129 <210> 1330 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1330 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Met Ser Gly Leu Gln Pro Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Ser Val Val Phe Gly Gly 35 40 <210> 1331 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1331 cctgatcggt tttctggctc caagtctggc aacacggcct ccctgaccat ctctggactc 60 cagcctgagg atgaatctga ttattactgc tgctcatatg caggcactta cagtgttgta 120 ttcggcgga 129 <210> 1332 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1332 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Pro Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Ser Val Val Phe Gly Gly 35 40 <210> 1333 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1333 cctgatcggt tttctggctc caaggctcgc aacacggcct ccctgaccat ctctggactc 60 cagcctgagg atgaatctga ttattactgc tgctcatatg caggcactta cagtgttgta 120 ttcggcgga 129 <210> 1334 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1334 Pro Asp Arg Phe Ser Gly Ser Lys Ala Arg Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Pro Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Ser Val Val Phe Gly Gly 35 40 <210> 1335 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1335 cctgatcggt tctctggctc caagtctggc aacacggcct ccctgaccat ctctggactc 60 cagcccgagg atgaatctga ttattactgc tgctcatatg caggcactta cagtgttgta 120 ttcggcgga 129 <210> 1336 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1336 cctgatcggt gttctggctc caagtctggc aacacggcct cccagaccat ctctggactc 60 cagcctgagg atgaatctga ttattactgc tgctcatatg caggcactta cagtgttgta 120 ttcggcgga 129 <210> 1337 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1337 Pro Asp Arg Cys Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Gln Thr 1 5 10 15 Ile Ser Gly Leu Gln Pro Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Ser Val Val Phe Gly Gly 35 40 <210> 1338 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1338 cctgatcggc tttctggctc caagtctggc aacgcggcct ccctgaccat ctctggactc 60 cagcctgagg atgaatctga ttattactgc tgctcatatg caggcactta cagtgttgta 120 ttcggcgga 129 <210> 1339 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1339 Pro Asp Arg Leu Ser Gly Ser Lys Ser Gly Asn Ala Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Pro Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Ser Val Val Phe Gly Gly 35 40 <210> 1340 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1340 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Ala Leu Phe 1 5 10 <210> 1341 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1341 tttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcgctc 120 ttcggaact 129 <210> 1342 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1342 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Leu Phe Gly Thr 35 40 <210> 1343 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1343 gttcgcctct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcgctc 120 ttcggaact 129 <210> 1344 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1344 Val Arg Leu Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Leu Phe Gly Thr 35 40 <210> 1345 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1345 gatcgcttct ctggctccat gtctggcaac acggcctccc tgaccatctc tgggctcctg 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcgctc 120 ttcggaact 129 <210> 1346 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1346 Asp Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Leu Phe Gly Thr 35 40 <210> 1347 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1347 gatcgcttct ctggctccaa gtctggcaac tcggcctccc tgaccatctc tgggctccag 60 gctgatgatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcgctc 120 ttcggaact 129 <210> 1348 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1348 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Leu Phe Gly Thr 35 40 <210> 1349 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1349 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcgctc 120 ttcggaact 129 <210> 1350 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1350 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Leu Phe Gly Thr 35 40 <210> 1351 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1351 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcgctc 120 ttcggaact 129 <210> 1352 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1352 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Ala Leu Phe Gly Thr 35 40 <210> 1353 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1353 atacgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgcgctc 120 ttcggaact 129 <210> 1354 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1354 Cys Ser Tyr Ala Gly Ser Ser Thr Pro Tyr Val Val Phe 1 5 10 <210> 1355 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1355 tgcctctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcactcc ctatgtggta 120 ttcggcgga 129 <210> 1356 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1356 Cys Leu Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Tyr Val Val Phe Gly Gly 35 40 <210> 1357 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1357 cgcttctctg gctccatgtc tggcaactcg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcactcc ctatgtggta 120 ttcggcgga 129 <210> 1358 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1358 Arg Phe Ser Gly Ser Met Ser Gly Asn Ser Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Tyr Val Val Phe Gly Gly 35 40 <210> 1359 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1359 cgcttctctg gctccaagtc tggctactcg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcactcc ctatgtggta 120 ttcggcgga 129 <210> 1360 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1360 Arg Phe Ser Gly Ser Lys Ser Gly Tyr Ser Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Tyr Val Val Phe Gly Gly 35 40 <210> 1361 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1361 cgcttctctg gctccaagtc tggcatcacg gcctccctga cactctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcactcc ctatgtggta 120 ttcggcgga 129 <210> 1362 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1362 Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr Leu Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Tyr Val Val Phe Gly Gly 35 40 <210> 1363 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1363 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcactcc ctatgtggta 120 ttcggcgga 129 <210> 1364 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1364 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Tyr Val Val Phe Gly Gly 35 40 <210> 1365 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1365 agcttctctt gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcactcc ctatgtggta 120 ttcggcgga 129 <210> 1366 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1366 Ser Phe Ser Cys Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Tyr Val Val Phe Gly Gly 35 40 <210> 1367 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1367 agcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcgggta gtagcactcc ctatgtggta 120 ttcggcgga 129 <210> 1368 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1368 Ser Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Pro Tyr Val Val Phe Gly Gly 35 40 <210> 1369 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1369 Cys Ser Tyr Ala Gly Ser Tyr Thr Leu Gly Val Phe 1 5 10 <210> 1370 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1370 gatcgcttct ctggctccaa gtcttgcaac acggcctccc tgtccatctc tggcctccat 60 gctgaggatg aggctaatta ttactgctgc tcatatgcag gcagctacac tttgggggta 120 ttcggcgga 129 <210> 1371 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1371 Asp Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu His Ala Glu Asp Glu Ala Asn Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Gly Val Phe Gly Gly 35 40 <210> 1372 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1372 gatcgcttct ctggctccaa gtctggctac acggcctccc tgacgatctc tggcctccag 60 gctgaggatg aggctaatta ttactgctgc tcatatgcag gcagctacac tttgggggta 120 ttcggcgga 129 <210> 1373 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1373 Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asn Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Gly Val Phe Gly Gly 35 40 <210> 1374 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1374 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tggcctccag 60 gctgaggatg aggctaatta ttactgctgc tcatatgcag gcagctacac tttgggggta 120 ttcggcgga 129 <210> 1375 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1375 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asn Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Gly Val Phe Gly Gly 35 40 <210> 1376 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1376 gatcgcttct ctggctccaa ggctggcaac acggcctccc tgaccatctc tggcctccag 60 gctgaggatg aggctaatta ttactgctgc tcatatgcag gcagctacac tttgggggta 120 ttcggcggg 129 <210> 1377 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1377 Asp Arg Phe Ser Gly Ser Lys Ala Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asn Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Gly Val Phe Gly Gly 35 40 <210> 1378 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1378 gttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tggcctccag 60 gctgaggatg aggctaatta ttactgctgc tcatatgcag gcagctacac tttgggggta 120 ttcggcgga 129 <210> 1379 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1379 Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asn Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Gly Val Phe Gly Gly 35 40 <210> 1380 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1380 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tggcctccag 60 gctgaggatg aggctaatta ttactgctgc tcatatgcag gcagctacac tttgggggta 120 ttcggcgga 129 <210> 1381 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1381 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asn Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Gly Val Phe Gly Gly 35 40 <210> 1382 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1382 atacgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tggcctccag 60 gctgaggatg aggctaatta ttactgctgc tcatatgcag gcagctacac tttgggggta 120 ttcggcgga 129 <210> 1383 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1383 Cys Ser Tyr Ala Gly Ser Tyr Arg Tyr Val Phe 1 5 10 <210> 1384 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1384 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ccgttatgtc 120 ttcggaact 129 <210> 1385 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1385 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Arg Tyr Val Phe Gly Thr 35 40 <210> 1386 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1386 ctgatacgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ccgttatgtc 120 ttcggaact 129 <210> 1387 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1387 cctgatcgct tctctggctc caagtctggg aactcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ccgttatgtc 120 ttcggaact 129 <210> 1388 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1388 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Arg Tyr Val Phe Gly Thr 35 40 <210> 1389 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1389 cctgatcgct tctctggctc caagtctggc tacacggcct acctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ccgttatgtc 120 ttcggaact 129 <210> 1390 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1390 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Tyr Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Arg Tyr Val Phe Gly Thr 35 40 <210> 1391 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1391 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atggggctga ttattactgc tgctcatatg caggcagcta ccgctatgtc 120 ttcggaact 129 <210> 1392 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1392 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Gly Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Arg Tyr Val Phe Gly Thr 35 40 <210> 1393 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1393 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ccgttatgtc 120 ttcggaact 129 <210> 1394 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1394 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Arg Tyr Val Phe Gly Thr 35 40 <210> 1395 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1395 cctgatcgat tctctggctc caagtctggc aactcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ccgttatgtc 120 ttcggaact 129 <210> 1396 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1396 Cys Ser Tyr Ala Gly Ser Tyr Thr Ser Phe Val Phe 1 5 10 <210> 1397 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1397 gatcgcttct ctggctccaa gtctggctac acggcctccc tgaccatctc tgtgctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttcctttgtc 120 ttcggaact 129 <210> 1398 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1398 Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Phe Val Phe Gly Thr 35 40 <210> 1399 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1399 gatcgcttct ctggctccaa gtctggcatc tcggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttcctttgtc 120 ttcggaact 129 <210> 1400 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1400 Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Phe Val Phe Gly Thr 35 40 <210> 1401 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1401 gatcgcttct ctggctccaa gtctggcaac actgactccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttcctttgtc 120 ttcggaact 129 <210> 1402 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1402 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Asp Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Phe Val Phe Gly Thr 35 40 <210> 1403 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1403 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgctta ttactgctgc tcatatgcgg gcagctacac ttcctttgtc 120 ttcggaact 129 <210> 1404 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1404 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Ala Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Phe Val Phe Gly Thr 35 40 <210> 1405 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1405 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttcctttgtc 120 ttcggaact 129 <210> 1406 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1406 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Phe Val Phe Gly Thr 35 40 <210> 1407 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1407 tttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttcctttgtc 120 ttcggaact 129 <210> 1408 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1408 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Phe Val Phe Gly Thr 35 40 <210> 1409 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1409 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ttcctttgtc 120 ttcggaact 129 <210> 1410 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1410 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Phe Val Phe Gly Thr 35 40 <210> 1411 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1411 Cys Ser Tyr Ala Gly Ser Tyr Pro Trp Val Phe 1 5 10 <210> 1412 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1412 cctgttcgct tctctggctg caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cccttgggtg 120 ttcggcgga 129 <210> 1413 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1413 Pro Val Arg Phe Ser Gly Cys Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Pro Trp Val Phe Gly Gly 35 40 <210> 1414 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1414 cctgttcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 cagtctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cccttgggtg 120 ttcggcgga 129 <210> 1415 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1415 Pro Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Pro Trp Val Phe Gly Gly 35 40 <210> 1416 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1416 cctgatcgct tctctggctc caggtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atggggctga ttattactgc tgctcatacg caggcagcta cccttgggtg 120 ttcggcgga 129 <210> 1417 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1417 Pro Asp Arg Phe Ser Gly Ser Arg Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Gly Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Pro Trp Val Phe Gly Gly 35 40 <210> 1418 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1418 cctgatcgct tctctggctc caagtctggc aactcggcct cgctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cccttgggtg 120 ttcggcgga 129 <210> 1419 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1419 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Pro Trp Val Phe Gly Gly 35 40 <210> 1420 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1420 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cccttgggtg 120 ttcggcgga 129 <210> 1421 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1421 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Pro Trp Val Phe Gly Gly 35 40 <210> 1422 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1422 ccgtttcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cccttgggtg 120 ttcggcgga 129 <210> 1423 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1423 Pro Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Pro Trp Val Phe Gly Gly 35 40 <210> 1424 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1424 cctgatcgct tctctggctc caagtctggc tacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cccttgggtg 120 ttcggcgga 129 <210> 1425 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1425 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Pro Trp Val Phe Gly Gly 35 40 <210> 1426 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1426 Cys Ser Tyr Ala Gly Ser Tyr Gly Val Val Phe 1 5 10 <210> 1427 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1427 ctgttccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cggggtggta 120 ttcggcgga 129 <210> 1428 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1428 Leu Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Gly Val Val Phe Gly Gly 35 40 <210> 1429 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1429 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cggggtggta 120 ttcggcgga 129 <210> 1430 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1430 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Gly Val Val Phe Gly Gly 35 40 <210> 1431 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1431 cctgatcgct tctctggctc caagtctggc aagacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg cgggcagcta cggggtggta 120 ttcggcgga 129 <210> 1432 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1432 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Gly Val Val Phe Gly Gly 35 40 <210> 1433 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1433 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggttc 60 caggctgagg atgaggctga ttattaccgc tgctcatatg caggcagcta cggggtggta 120 ttcggcgga 129 <210> 1434 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1434 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Phe Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Arg Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Gly Val Val Phe Gly Gly 35 40 <210> 1435 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1435 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgatg atgaggctga ttattactgc tgctcatatg caggcagcta cggggtggtt 120 ttcggcgga 129 <210> 1436 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1436 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Gly Val Val Phe Gly Gly 35 40 <210> 1437 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1437 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cggggtggta 120 ttcggcgga 129 <210> 1438 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1438 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Gly Val Val Phe Gly Gly 35 40 <210> 1439 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1439 cctgatcgct tctctggctc caagtctggc aacactgcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cggggtggta 120 ttcggcgga 129 <210> 1440 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1440 Cys Ser Tyr Ala Gly Ser Arg Val Phe 1 5 <210> 1441 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1441 gggtttctaa tccgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtagggtg 120 ttcggcgga 129 <210> 1442 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1442 Gly Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Arg Val Phe Gly Gly 35 40 <210> 1443 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1443 aggggtttct atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtagggtg 120 ttcggcgga 129 <210> 1444 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1444 Arg Gly Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Arg Val Phe Gly Gly 35 40 <210> 1445 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1445 gtggtttcta atcgcttctc tggctccaag tcttgcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtagggtg 120 ttcggcgga 129 <210> 1446 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1446 Val Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Arg Val Phe Gly Gly 35 40 <210> 1447 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1447 ggggtttcta ttcgcttctc tggctccaag tctggcaaca cggcctccct gactatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtagggtg 120 ttcggcgga 129 <210> 1448 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1448 Gly Val Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Arg Val Phe Gly Gly 35 40 <210> 1449 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1449 ggggtttcta atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagtagggtg 120 ttcggcgga 129 <210> 1450 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1450 Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Arg Val Phe Gly Gly 35 40 <210> 1451 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1451 Cys Ser Tyr Ala Gly Ser Ser Thr Leu Tyr Val Phe 1 5 10 <210> 1452 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1452 aatcgcttct ctggctccaa gtctggcatc acggcctcgc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tctttatgtc 120 ttcggaact 129 <210> 1453 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1453 Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Leu Tyr Val Phe Gly Thr 35 40 <210> 1454 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1454 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tctttatgtc 120 ttcggaact 129 <210> 1455 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1455 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Leu Tyr Val Phe Gly Thr 35 40 <210> 1456 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1456 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatacgcag gtagtagcac tttgtatgtc 120 ttcggaact 129 <210> 1457 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1457 aatcgcttct ccggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tctttatgtc 120 ttcggaact 129 <210> 1458 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1458 aatcgcctct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac cctttatgtc 120 ttcggaact 129 <210> 1459 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1459 Asn Arg Leu Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Leu Tyr Val Phe Gly Thr 35 40 <210> 1460 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1460 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tctttatgtc 120 ttcggaact 129 <210> 1461 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1461 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Leu Tyr Val Phe Gly Thr 35 40 <210> 1462 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1462 Cys Ser Tyr Gly Gly Thr Tyr Thr Val Phe 1 5 10 <210> 1463 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1463 tccctgatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atggaggcac ctacacagtg 120 ttcggcgaa 129 <210> 1464 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1464 Ser Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Gly Gly Thr Tyr Thr Val Phe Gly Glu 35 40 <210> 1465 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1465 gtccctgatc gcttctctgt ctccaagtct ggctacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atggaggcac ctacacagtg 120 ttcggcgaa 129 <210> 1466 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1466 Val Pro Asp Arg Phe Ser Val Ser Lys Ser Gly Tyr Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Gly Gly Thr Tyr Thr Val Phe Gly Glu 35 40 <210> 1467 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1467 gtccctgatc gcttctctgg ctcgaagtct ggcaacacgg cctccctgac gatctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atggaggcac ctacacagtg 120 ttcggcgaa 129 <210> 1468 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1468 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Gly Gly Thr Tyr Thr Val Phe Gly Glu 35 40 <210> 1469 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1469 gtccctgatc gcttctctgg ctccaagtct tgcaacacgg cctccctgac catctctgtg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atggaggcac ctacacagtg 120 ttcggcgaa 129 <210> 1470 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1470 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Gly Gly Thr Tyr Thr Val Phe Gly Glu 35 40 <210> 1471 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1471 gtccctgatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atggaggcac ctacacagtg 120 ttcggcgaa 129 <210> 1472 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1472 gtccctgatc gcttctccgg ctccaagtct ggcaacacgg ccttcctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atggaggcac ctacacagtg 120 ttcggcgaa 129 <210> 1473 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1473 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Phe Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Gly Gly Thr Tyr Thr Val Phe Gly Glu 35 40 <210> 1474 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1474 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Asn Trp Val Phe 1 5 10 <210> 1475 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1475 cgcttctctg tctccaagtc tgtcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt caattgggtg 120 ttcggcgga 129 <210> 1476 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1476 Arg Phe Ser Val Ser Lys Ser Val Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Asn Trp Val Phe Gly Gly 35 40 <210> 1477 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1477 cgcttctctg gctccatgtc tggcaactcg gcctccctga ctatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt caattgggtg 120 ttcggcgga 129 <210> 1478 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1478 Arg Phe Ser Gly Ser Met Ser Gly Asn Ser Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Asn Trp Val Phe Gly Gly 35 40 <210> 1479 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1479 cgcttctctg gctccaagtc tggcaactcg gcctccctga ctatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt caattgggtg 120 ttcggcgga 129 <210> 1480 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1480 Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Asn Trp Val Phe Gly Gly 35 40 <210> 1481 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1481 cgcttctctg gctccaagtc tggcaacacg gcctccctga cattctctgg gctgcaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt caattgggtg 120 ttcggcgga 129 <210> 1482 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1482 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Phe Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Asn Trp Val Phe Gly Gly 35 40 <210> 1483 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1483 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gatgacgagt ctgattatta ctgctgctca tatgcaggta gtagcacttt caattgggtg 120 ttcggcgga 129 <210> 1484 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1484 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Asp Asp Glu Ser Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Asn Trp Val Phe Gly Gly 35 40 <210> 1485 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1485 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt caattgggtg 120 ttcggcgga 129 <210> 1486 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1486 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Asn Trp Val Phe Gly Gly 35 40 <210> 1487 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1487 Cys Ser Tyr Ala Gly Arg Tyr Val Phe 1 5 <210> 1488 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1488 ggggtccctg atcgcttctc tggctccaag tctggcaaca cggcctccct gtccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagatatgtc 120 ttcggatct 129 <210> 1489 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1489 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Ser Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Arg Tyr Val Phe Gly Ser 35 40 <210> 1490 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1490 gggtccctga tccgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagatatgtc 120 ttcggaact 129 <210> 1491 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1491 Gly Ser Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Arg Tyr Val Phe Gly Thr 35 40 <210> 1492 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1492 ggtgtccctg atcgcttctc tggctccaag tctggcatca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagatatgtc 120 ttcggaact 129 <210> 1493 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1493 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Arg Tyr Val Phe Gly Thr 35 40 <210> 1494 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1494 ggggtccctg atcgcttctc tgtctccaag tctggcatca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagatatgtc 120 ttcggaact 129 <210> 1495 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1495 Gly Val Pro Asp Arg Phe Ser Val Ser Lys Ser Gly Ile Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Arg Tyr Val Phe Gly Thr 35 40 <210> 1496 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1496 ggggtccctg atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagatatgtc 120 ttcggaact 129 <210> 1497 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1497 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Arg Tyr Val Phe Gly Thr 35 40 <210> 1498 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1498 gttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctcctg 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttgggggtc 120 ttcggaact 129 <210> 1499 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1499 Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Gly Val Phe Gly Thr 35 40 <210> 1500 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1500 gttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttgggtgtc 120 ttcggaact 129 <210> 1501 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1501 Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Gly Val Phe Gly Thr 35 40 <210> 1502 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1502 gatcgcttct ctggctccaa gtctggcaag acggcctgcc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttgggggtc 120 ttcggaact 129 <210> 1503 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1503 Asp Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Cys Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Gly Val Phe Gly Thr 35 40 <210> 1504 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1504 gatcgcttct ctggctccaa gtctggcaac tcggcctccc tgacgatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttgggggtc 120 ttcggaact 129 <210> 1505 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1505 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Gly Val Phe Gly Thr 35 40 <210> 1506 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1506 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttgggggtc 120 ttcggaact 129 <210> 1507 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1507 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Gly Val Phe Gly Thr 35 40 <210> 1508 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1508 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttgggggtc 120 ttcggaact 129 <210> 1509 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1509 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Gly Val Phe Gly Thr 35 40 <210> 1510 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1510 Cys Ser Ser Pro Asp Ser Asn Thr Val Val Phe 1 5 10 <210> 1511 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1511 tctcatcgct tctctggtac caagtctggc tacacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgttcatctc cagatagtaa cactgttgtg 120 ttcggagga 129 <210> 1512 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1512 Ser His Arg Phe Ser Gly Thr Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Ser Pro Asp Ser Asn Thr Val Val Phe Gly Gly 35 40 <210> 1513 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1513 tctcatcgct tctctggtac caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgttcatctc cagatagtaa cactgttgtg 120 ttcggagga 129 <210> 1514 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1514 Ser His Arg Phe Ser Gly Thr Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Ser Pro Asp Ser Asn Thr Val Val Phe Gly Gly 35 40 <210> 1515 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1515 tctattcgct tctctggctc caactctggc gacacggcct ccctgactat ctctggactc 60 caggctgagg acgaggctga ttattactgc tgttcatctc cagacagtaa tactgttgtg 120 ttcggagga 129 <210> 1516 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1516 Ser Ile Arg Phe Ser Gly Ser Asn Ser Gly Asp Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Ser Pro Asp Ser Asn Thr Val Val Phe Gly Gly 35 40 <210> 1517 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1517 tctaatcgct tctctggctc caactctggc gacacggcct ccctgacaat ctctggactc 60 caggctgagg acgaggctga ttattactgc tgttcatctc cagacagtaa tactgttgtg 120 ttcggagga 129 <210> 1518 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1518 Ser Asn Arg Phe Ser Gly Ser Asn Ser Gly Asp Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Ser Pro Asp Ser Asn Thr Val Val Phe Gly Gly 35 40 <210> 1519 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1519 cttattcgct tctctggctc caactctggc gacacggcct ccctgacaat ctctggactc 60 caggctgagg acgaggctga ttattactgc tgttcatctc cagacagtaa tactgttgtg 120 ttcggagga 129 <210> 1520 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1520 Leu Ile Arg Phe Ser Gly Ser Asn Ser Gly Asp Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Ser Pro Asp Ser Asn Thr Val Val Phe Gly Gly 35 40 <210> 1521 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1521 ctcatccgct tctctggtac caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgttcatctc cagatagtaa cactgttgtg 120 ttcggagga 129 <210> 1522 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1522 Leu Ile Arg Phe Ser Gly Thr Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Ser Pro Asp Ser Asn Thr Val Val Phe Gly Gly 35 40 <210> 1523 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1523 Cys Ser Tyr Ala Gly Thr Tyr Ser Leu Val Phe 1 5 10 <210> 1524 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1524 cctggccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta ctccttggtg 120 ttcggcgga 129 <210> 1525 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1525 Pro Gly Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Ser Leu Val Phe Gly Gly 35 40 <210> 1526 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1526 cctgatcgct tctctggctc gaagtctggc aacacggcct ccctgaccat ctctgtgctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta ctccttggtg 120 ttcggcgga 129 <210> 1527 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1527 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Ser Leu Val Phe Gly Gly 35 40 <210> 1528 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1528 cctgatcgct tctctggctc cacggctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta ctccttggtg 120 ttcggcgga 129 <210> 1529 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1529 Pro Asp Arg Phe Ser Gly Ser Thr Ala Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Ser Leu Val Phe Gly Gly 35 40 <210> 1530 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1530 cctgatcgct tctctggctc caagtctggc aacacggcct ccctggccat ctctgggccc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta ctccttggtg 120 ttcggcgga 129 <210> 1531 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1531 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala 1 5 10 15 Ile Ser Gly Pro Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Ser Leu Val Phe Gly Gly 35 40 <210> 1532 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1532 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta ctccttggtg 120 ttcggcgga 129 <210> 1533 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1533 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Ser Leu Val Phe Gly Gly 35 40 <210> 1534 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1534 cctgatcgct tccctggctc catgtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta ctccttggtg 120 ttcggcgga 129 <210> 1535 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1535 Pro Asp Arg Phe Pro Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Ser Leu Val Phe Gly Gly 35 40 <210> 1536 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1536 Cys Ser Tyr Ala Ser Ser Ser Thr Leu Val Phe 1 5 10 <210> 1537 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1537 tcttatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg ctagtagtag cactttagtg 120 ttcggcgga 129 <210> 1538 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1538 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Ser Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1539 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1539 tctaatcgct tctctggctc caagtctggc tacacggcct ccctgacatt ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caagtagtag cactttagtg 120 ttcggcgga 129 <210> 1540 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1540 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Ser Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1541 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1541 tctaatcgct tctctggctc caagtctggc aacactgcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caagtagtag cactttagtg 120 ttcggcgga 129 <210> 1542 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1542 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Ser Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1543 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1543 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caagtagtag cactttagtg 120 ttcggcgga 129 <210> 1544 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1544 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Ser Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1545 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1545 tctaatcgct tctctggctc caagtccggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caagtagtag cactttagtg 120 ttcagcgga 129 <210> 1546 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1546 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Ser Ser Ser Thr Leu Val Phe Ser Gly 35 40 <210> 1547 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1547 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caagtagtag cactttagtg 120 ttcggcgga 129 <210> 1548 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1548 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Ser Ser Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1549 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1549 Cys Ser Phe Ala Gly Ser His Thr Tyr Val Phe 1 5 10 <210> 1550 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1550 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcca cacttatgtc 120 ttcggaact 129 <210> 1551 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1551 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser His Thr Tyr Val Phe Gly Thr 35 40 <210> 1552 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1552 ctgatacgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcca cacttatgtc 120 ttcggaact 129 <210> 1553 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1553 cctgatcgct tctctggctc caagtctggc atcacggcct ccctgaccat ctctgggctc 60 cagtctgagg atgaggctga ttattactgc tgctcatttg caggcagcca cacttatgtc 120 ttcggaact 129 <210> 1554 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1554 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser His Thr Tyr Val Phe Gly Thr 35 40 <210> 1555 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1555 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcca cacttatgtc 120 ttcggaact 129 <210> 1556 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1556 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser His Thr Tyr Val Phe Gly Thr 35 40 <210> 1557 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1557 ccgtttcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcca cacttatgtc 120 ttcggaact 129 <210> 1558 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1558 Pro Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser His Thr Tyr Val Phe Gly Thr 35 40 <210> 1559 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1559 cctgatcgct tctctggctc caagtctggc tacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatttg caggcagcca cacttatgtc 120 ttcggaact 129 <210> 1560 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1560 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Ala Gly Ser His Thr Tyr Val Phe Gly Thr 35 40 <210> 1561 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1561 Cys Ser Tyr Ala Gly Ser Ser Ile Tyr Val Phe 1 5 10 <210> 1562 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1562 tctattcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctctgggctc 60 cagtctgagg acgaggctga ttattactgc tgctcatatg caggtagtag catttatgtc 120 ttcggaact 129 <210> 1563 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1563 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ile Tyr Val Phe Gly Thr 35 40 <210> 1564 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1564 tctaatcgct tctctggctc cgagtccggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag catttatgtc 120 ttcggaact 129 <210> 1565 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1565 Ser Asn Arg Phe Ser Gly Ser Glu Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ile Tyr Val Phe Gly Thr 35 40 <210> 1566 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1566 tctaatcgct tctctggctc caagtctggt aacacggcct ccctgacaat ctctgggccc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag catttatgtc 120 ttcggaact 129 <210> 1567 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1567 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Pro Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ile Tyr Val Phe Gly Thr 35 40 <210> 1568 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1568 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag catttatgtc 120 ttcggaact 129 <210> 1569 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1569 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ile Tyr Val Phe Gly Thr 35 40 <210> 1570 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1570 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag catttatgtc 120 ttcggaact 129 <210> 1571 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1571 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ile Tyr Val Phe Gly Thr 35 40 <210> 1572 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1572 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag catttatgtc 120 ttcggaact 129 <210> 1573 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1573 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ile Tyr Val Phe Gly Thr 35 40 <210> 1574 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1574 Cys Ser Tyr Ala Gly Ser Ser Thr Lys Val Phe 1 5 10 <210> 1575 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1575 tctagtcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattaccgc tgctcatatg caggtagtag cacaaaggtg 120 ttcggcgga 129 <210> 1576 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1576 Ser Ser Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Arg Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Lys Val Phe Gly Gly 35 40 <210> 1577 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1577 tctaatcgct tctctggctc caagtctggc cacccggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacaaaggtg 120 ttcggcgga 129 <210> 1578 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1578 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly His Pro Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Lys Val Phe Gly Gly 35 40 <210> 1579 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1579 tctaatcgct tctctggctc caagtctggc aagacggcct ccctgacaat ctctgtgctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacaaaggtg 120 ttcggcgga 129 <210> 1580 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1580 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Lys Val Phe Gly Gly 35 40 <210> 1581 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1581 tctaatcgct tctctggctc caagtctggc aactcggcct cgctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacaaaggtg 120 ttcggcgga 129 <210> 1582 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1582 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Lys Val Phe Gly Gly 35 40 <210> 1583 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1583 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacaaaggtg 120 ttcggcgga 129 <210> 1584 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1584 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Lys Val Phe Gly Gly 35 40 <210> 1585 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1585 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacaaaggtg 120 ttcggcgga 129 <210> 1586 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1586 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Lys Val Phe Gly Gly 35 40 <210> 1587 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1587 Cys Ser Tyr Ala Gly Ser Tyr Leu Tyr Val Phe 1 5 10 <210> 1588 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1588 cgtgatcgct tctctggctc caagtctggc aacactgcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cctctatgtc 120 ttcggaact 129 <210> 1589 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1589 Arg Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Leu Tyr Val Phe Gly Thr 35 40 <210> 1590 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1590 cctgatcgct tctctggctc caagtctggc tacacggcct ccctgacgat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cctctatgtc 120 ttcggaact 129 <210> 1591 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1591 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Leu Tyr Val Phe Gly Thr 35 40 <210> 1592 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1592 cctgatcgct tctctggctc caagtctggc aactcggcct ccctgaccat ctcttggctc 60 cagactgggg atgaggctga ttattactgc tgctcatatg caggcagcta cctttatgtc 120 ttcggaact 129 <210> 1593 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1593 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Thr Gly Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Leu Tyr Val Phe Gly Thr 35 40 <210> 1594 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1594 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cctctatgtc 120 ttcggaact 129 <210> 1595 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1595 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Leu Tyr Val Phe Gly Thr 35 40 <210> 1596 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1596 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 cagactgggg atgaggctga ttattactgc tgctcatatg caggcagcta cctttatgtc 120 ttcggaact 129 <210> 1597 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1597 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Thr Gly Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Leu Tyr Val Phe Gly Thr 35 40 <210> 1598 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1598 cctgatcgct tctctgaccc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cctctatgtc 120 ttcggaact 129 <210> 1599 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1599 Pro Asp Arg Phe Ser Asp Pro Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Leu Tyr Val Phe Gly Thr 35 40 <210> 1600 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1600 Cys Ser Tyr Ala Gly Ser Ser Ile Val Val Phe 1 5 10 <210> 1601 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1601 tctaatcgct tctctggctc caagtctggg aacacgggct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cattgtggta 120 ttcggcgga 129 <210> 1602 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1602 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Gly Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ile Val Val Phe Gly Gly 35 40 <210> 1603 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1603 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacatt ctctgggctc 60 ctggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cattgtggta 120 ttcggcgga 129 <210> 1604 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1604 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ile Val Val Phe Gly Gly 35 40 <210> 1605 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1605 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cattgtggta 120 ttcggcgga 129 <210> 1606 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1606 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ile Val Val Phe Gly Gly 35 40 <210> 1607 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1607 tctaatcgct tctctggctc caagtctggc aacacggcct ccctcacaat ctctgggctc 60 caggctgagg acgaggctga ttattacttc tgctcatatg caggtagtag cattgtggta 120 ttcggcgga 129 <210> 1608 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1608 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Phe Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ile Val Val Phe Gly Gly 35 40 <210> 1609 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1609 ctaattcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cattgtggta 120 ttcggcgga 129 <210> 1610 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1610 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ile Val Val Phe Gly Gly 35 40 <210> 1611 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1611 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cattgtggta 120 ttcggcgga 129 <210> 1612 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1612 Cys Ser Tyr Ala Gly Ser Arg Thr Pro Val Val Phe 1 5 10 <210> 1613 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1613 aatcgcttct ctggctccaa gtctgtcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg atgctgatta ttactgctgc tcatatgcag gaagtagaac tcccgtggta 120 ttcggcgga 129 <210> 1614 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1614 Asn Arg Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Asp Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Arg Thr Pro Val Val Phe Gly Gly 35 40 <210> 1615 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1615 aatcgcttct ctggctccaa gtctggctac agggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gaagtagaac tcccgtggta 120 ttcggcgga 129 <210> 1616 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1616 Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Arg Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Arg Thr Pro Val Val Phe Gly Gly 35 40 <210> 1617 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1617 aatcgcttct ctggctccaa gtctggcatg acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gaagtagaac tcccgtggtt 120 ttcggcgga 129 <210> 1618 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1618 Asn Arg Phe Ser Gly Ser Lys Ser Gly Met Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Arg Thr Pro Val Val Phe Gly Gly 35 40 <210> 1619 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1619 aatcgcttct ctggctccaa gtctggcaac actgcctccc tgacaatctc tgggctcctg 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gaagtagaac tcccgtggta 120 ttcggcgga 129 <210> 1620 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1620 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Arg Thr Pro Val Val Phe Gly Gly 35 40 <210> 1621 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1621 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gaagtagaac tcccgtggta 120 ttcggcgga 129 <210> 1622 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1622 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Arg Thr Pro Val Val Phe Gly Gly 35 40 <210> 1623 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1623 aatcgcttct ctggccccaa gtctggcaac acggcctgcc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gaagtagaac tcccgtggta 120 ttcggcgga 129 <210> 1624 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1624 Asn Arg Phe Ser Gly Pro Lys Ser Gly Asn Thr Ala Cys Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Arg Thr Pro Val Val Phe Gly Gly 35 40 <210> 1625 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1625 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Asp Val Val Phe 1 5 10 <210> 1626 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1626 cgcttctctt gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gcagcacttt tgatgtggta 120 ttcggcgga 129 <210> 1627 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1627 Arg Phe Ser Cys Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 1628 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1628 cgcttctctg gctccatgtc tggctacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt tgatgtggta 120 ttcggcgga 129 <210> 1629 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1629 Arg Phe Ser Gly Ser Met Ser Gly Tyr Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 1630 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1630 cgcttctctg gctccaagtc tggcaactcg gcctccgtga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt tgatgtggta 120 ttcggcgga 129 <210> 1631 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1631 Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Val Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 1632 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1632 cgcttctctg gctccaagtc tggcaacacg gcctgcctga caatctctgg gctccaggct 60 gatgacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt tgatgtggta 120 ttcggcgga 129 <210> 1633 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1633 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Cys Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 1634 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1634 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt tgatgtggta 120 ttcggcgga 129 <210> 1635 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1635 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Asp Val Val Phe Gly Gly 35 40 <210> 1636 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1636 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt cgatgtggta 120 ttcggcgga 129 <210> 1637 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1637 ttctatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagtc 120 ttcggaact 129 <210> 1638 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1638 Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Thr 35 40 <210> 1639 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1639 tcttatcgct tctctggctc caagtctggc tacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagtc 120 ttcggaact 129 <210> 1640 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1640 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Thr 35 40 <210> 1641 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1641 tcttatcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagtc 120 ttcggaact 129 <210> 1642 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1642 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Thr 35 40 <210> 1643 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1643 tctaatctct tctctggctc caagtctggc aagacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggtc 120 ttcggaact 129 <210> 1644 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1644 Ser Asn Leu Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Thr 35 40 <210> 1645 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1645 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttggtc 120 ttcggaact 129 <210> 1646 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1646 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Val Phe Gly Thr 35 40 <210> 1647 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1647 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagtc 120 ttcggaact 129 <210> 1648 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1648 Cys Ser Tyr Ala Gly Ser Arg Leu Leu Val Phe 1 5 10 <210> 1649 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1649 ttctatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgacg acgaggctga ttattactgc tgctcatatg caggtagtcg cctcctggta 120 ttcggcgga 129 <210> 1650 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1650 Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Leu Leu Val Phe Gly Gly 35 40 <210> 1651 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1651 tctattcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caagctgacg acgaggctga ttattactgc tgctcatatg caggtagtcg cctcctggta 120 ttcggcgga 129 <210> 1652 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1652 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Leu Leu Val Phe Gly Gly 35 40 <210> 1653 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1653 tctaatcgct tctctggctc caagtctggc atcacgggct ccctgacaat ctctgggctc 60 caggctgacg acgaggctga ttattactgc tgctcatatg caggtagtcg cctcctggta 120 ttcggcgga 129 <210> 1654 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1654 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Gly Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Leu Leu Val Phe Gly Gly 35 40 <210> 1655 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1655 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgacg acgaggctga ttattactgc tgctcatatg caggtagtcg cctcctggta 120 ttcggcgga 129 <210> 1656 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1656 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Leu Leu Val Phe Gly Gly 35 40 <210> 1657 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1657 tcaaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggccc 60 caggctgacg acgaggctga ttattactgc tgctcatatg caggtagtcg cctcctggta 120 ttcggcgga 129 <210> 1658 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1658 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Pro Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Leu Leu Val Phe Gly Gly 35 40 <210> 1659 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1659 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Val Phe 1 5 10 <210> 1660 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1660 cctgatcgct tctctggctc caagtctggc tacactgcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttcgta 120 ttcggcgga 129 <210> 1661 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1661 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Phe Val Phe Gly Gly 35 40 <210> 1662 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1662 cctgatcgct tctctggctc caagtctggc aagacgggct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttcgta 120 ttcggcgga 129 <210> 1663 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1663 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Gly Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Phe Val Phe Gly Gly 35 40 <210> 1664 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1664 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttcgta 120 ttcggcgga 129 <210> 1665 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1665 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Phe Val Phe Gly Gly 35 40 <210> 1666 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1666 cctgatcgct tctctggctc caagtctggc aacacggcct acctgaccat ctctgggctc 60 cagtctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttcgta 120 ttcggcgga 129 <210> 1667 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1667 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Tyr Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Phe Val Phe Gly Gly 35 40 <210> 1668 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1668 ccgtttcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactttcgta 120 ttcggcgga 129 <210> 1669 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1669 Pro Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Phe Val Phe Gly Gly 35 40 <210> 1670 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1670 Cys Ser Tyr Ala Gly Ser Thr Thr Arg Val Val Phe 1 5 10 <210> 1671 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1671 tatcgcttct ctggctccaa gtctggcaac acggcctccc tgtcaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtaccac tcgcgtggta 120 ttcggcgga 129 <210> 1672 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1672 Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Thr Thr Arg Val Val Phe Gly Gly 35 40 <210> 1673 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1673 tatcgcttct ctggctccaa ggctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtaccac tcgcgtggta 120 ttcggcgga 129 <210> 1674 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1674 Tyr Arg Phe Ser Gly Ser Lys Ala Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Thr Thr Arg Val Val Phe Gly Gly 35 40 <210> 1675 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1675 attcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctcgag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtaccac tcgcgtggta 120 ttcggcgga 129 <210> 1676 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1676 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Thr Thr Arg Val Val Phe Gly Gly 35 40 <210> 1677 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1677 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtaccac tcgcgtggta 120 ttcggcgga 129 <210> 1678 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1678 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Thr Thr Arg Val Val Phe Gly Gly 35 40 <210> 1679 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1679 attcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtaccac tcgcgtggta 120 ttcggcgga 129 <210> 1680 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1680 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Thr Thr Arg Val Val Phe Gly Gly 35 40 <210> 1681 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1681 Cys Ser Tyr Ala Gly Phe Ser Thr Leu Val Phe 1 5 10 <210> 1682 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1682 tctaatcgct tctctggctc caagtctgtc tacacggcct ccctgacaat ctcttggctc 60 caggctgagg acgaggctca ttactactgc tgctcatatg caggttttag cactttggta 120 ttcggcgga 129 <210> 1683 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1683 Ser Asn Arg Phe Ser Gly Ser Lys Ser Val Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala His Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Phe Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1684 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1684 tctaatcgct tctctggctc caagtctgtc atcacggcct ccctgacaat ctctgggctc 60 caggctgatg acgaggctca ttactactgc tgctcatatg caggttttag cactttggta 120 ttcggcgga 129 <210> 1685 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1685 Ser Asn Arg Phe Ser Gly Ser Lys Ser Val Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala His Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Phe Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1686 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1686 tctaatcgct tctctggctc caagtctgtc aagacggcct ccctgacaat ctctgggctc 60 caggctgagg acggggctca ttactactgc tgctcatatg caggttttag cactttggta 120 ttcggcgga 129 <210> 1687 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1687 Ser Asn Arg Phe Ser Gly Ser Lys Ser Val Lys Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Gly Ala His Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Phe Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1688 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1688 tctaatcgct tctctggctc caagtctgtc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctca ttactactgc tgctcatatg caggttttag cactttggta 120 ttcggcgga 129 <210> 1689 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1689 Ser Asn Arg Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala His Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Phe Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1690 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1690 ctaatccgct tctctggctc caagtctgtc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctca ttactactgc tgctcatatg caggttttag cactttggta 120 ttcggcgga 129 <210> 1691 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1691 Leu Ile Arg Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala His Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Phe Ser Thr Leu Val Phe Gly Gly 35 40 <210> 1692 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1692 Cys Ser Tyr Ala Gly Ser Leu Tyr Val Phe 1 5 10 <210> 1693 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1693 gtccctgatc gcttctctgg ctccaagtct ggcgacacgg cctccctgac catctctggg 60 ctccaggctg aggatggggc tgattattac tgctgctcat atgcaggcag cctctatgtc 120 ttcggaact 129 <210> 1694 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1694 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asp Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Gly Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Leu Tyr Val Phe Gly Thr 35 40 <210> 1695 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1695 gtccctgatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag cctctatgtc 120 ttcggaact 129 <210> 1696 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1696 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Leu Tyr Val Phe Gly Thr 35 40 <210> 1697 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1697 gtccctgata gcttctctgg ctccaagtct ggcaacacgg cctccctgac catgtctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag cctctatgtc 120 ttcggaact 129 <210> 1698 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1698 Val Pro Asp Ser Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Met Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Leu Tyr Val Phe Gly Thr 35 40 <210> 1699 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1699 gtccatgatc gcttctctgt ctccaagtct ggcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag cctctatgtc 120 ttcggaact 129 <210> 1700 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1700 Val His Asp Arg Phe Ser Val Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Leu Tyr Val Phe Gly Thr 35 40 <210> 1701 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1701 ggacctgatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag cctctatgtc 120 ttcggaact 129 <210> 1702 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1702 Gly Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Leu Tyr Val Phe Gly Thr 35 40 <210> 1703 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1703 Cys Ser Tyr Ala Gly Ser Arg Tyr Val Val Phe 1 5 10 <210> 1704 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1704 tgtaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgtgctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag atatgtggta 120 ttcggcgga 129 <210> 1705 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1705 Cys Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Tyr Val Val Phe Gly Gly 35 40 <210> 1706 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1706 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag atatgtggta 120 ttcggcgga 129 <210> 1707 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1707 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Tyr Val Val Phe Gly Gly 35 40 <210> 1708 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1708 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag atatgtggta 120 ttcggcgga 129 <210> 1709 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1709 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Tyr Val Val Phe Gly Gly 35 40 <210> 1710 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1710 tctaatcgct tctctggctc caagtctggc aacacagcca ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag atatgtggta 120 ttcggcgga 129 <210> 1711 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1711 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Thr Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Tyr Val Val Phe Gly Gly 35 40 <210> 1712 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1712 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag atatgtggta 120 ttcggcgga 129 <210> 1713 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1713 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Tyr Val Val Phe Gly Gly 35 40 <210> 1714 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1714 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Gly Val Phe 1 5 10 <210> 1715 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1715 gttcgcttct ctggctccaa gtctggcaac acggcctccc tgtccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcggggtc 120 ttcggaact 129 <210> 1716 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1716 Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Gly Val Phe Gly Thr 35 40 <210> 1717 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1717 gttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcggtgtc 120 ttcggaact 129 <210> 1718 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1718 Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Gly Val Phe Gly Thr 35 40 <210> 1719 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1719 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcggggtc 120 ttcggaact 129 <210> 1720 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1720 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Gly Val Phe Gly Thr 35 40 <210> 1721 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1721 gatcgcttct ctggctccaa ggcaggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcggggtc 120 ttcggaact 129 <210> 1722 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1722 Asp Arg Phe Ser Gly Ser Lys Ala Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Gly Val Phe Gly Thr 35 40 <210> 1723 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1723 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcggggtc 120 ttcggaact 129 <210> 1724 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1724 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Gly Val Phe Gly Thr 35 40 <210> 1725 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1725 Cys Ser Tyr Ala Gly Ser Arg Gly Val Val Phe 1 5 10 <210> 1726 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1726 tcttatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag gggggttgta 120 ttcggcgga 129 <210> 1727 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1727 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Gly Val Val Phe Gly Gly 35 40 <210> 1728 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1728 tctattcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag gggggtggta 120 ttcggcgga 129 <210> 1729 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1729 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Gly Val Val Phe Gly Gly 35 40 <210> 1730 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1730 tctaatcgct tctctggctc cttgtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag gggggtggta 120 ttcggcgga 129 <210> 1731 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1731 Ser Asn Arg Phe Ser Gly Ser Leu Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Gly Val Val Phe Gly Gly 35 40 <210> 1732 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1732 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag gggggtggta 120 ttcggcgga 129 <210> 1733 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1733 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Gly Val Val Phe Gly Gly 35 40 <210> 1734 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1734 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag gggggtggta 120 ttcggcgga 129 <210> 1735 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1735 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Gly Val Val Phe Gly Gly 35 40 <210> 1736 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1736 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Gly Val Val Phe 1 5 10 <210> 1737 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1737 cgcttctctg gctcgaagtc tggcaacacg gcctccctga ccatctctgt gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cggtgtggta 120 ttcggcgga 129 <210> 1738 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1738 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 1739 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1739 cgcttctctg gctccaagtc tggcaactcg gcctccctga ccttctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cggtgtggta 120 ttcggcgga 129 <210> 1740 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1740 Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Phe Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 1741 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1741 cgcttctctg gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cggtgtggta 120 ttcggcgga 129 <210> 1742 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1742 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 1743 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1743 tcgcttctct ggctccaagt ctggcaacac ggcctccctg accatctctg ggctcaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cggtgtggta 120 ttcggcgga 129 <210> 1744 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1744 Ser Leu Leu Trp Leu Gln Val Trp Gln His Gly Leu Pro Asp His Leu 1 5 10 15 Trp Ala Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 1745 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1745 tcgcttctct ggctccaagt ctggcaacac ggcctccctg accatctctg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cggtgtggta 120 ttcggcgga 129 <210> 1746 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1746 Ser Leu Leu Trp Leu Gln Val Trp Gln His Gly Leu Pro Asp His Leu 1 5 10 15 Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Gly Val Val Phe Gly Gly 35 40 <210> 1747 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1747 Cys Ser Tyr Ala Gly Arg Tyr Ser Phe Thr Ile Phe 1 5 10 <210> 1748 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1748 gatcgcttat ctggctccaa gtctggctac acggcctccc tgaccatctc tggactcgag 60 gctgaggatg aggctgatta ttattgctgc tcatatgcag gcaggtacag tttcactatc 120 ttcggaact 129 <210> 1749 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1749 Asp Arg Leu Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Arg Tyr Ser Phe Thr Ile Phe Gly Thr 35 40 <210> 1750 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1750 gatcgcttat ctggctccaa gtctggcaac tcggcctcgc tgaccatctc tggactccag 60 gctgaggatg aggctgatta ttattgctgc tcatatgcag gcaggtacag tttcactatc 120 ttcggaact 129 <210> 1751 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1751 Asp Arg Leu Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Arg Tyr Ser Phe Thr Ile Phe Gly Thr 35 40 <210> 1752 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1752 gatcgcttat ctggctccaa gtctggcaac acggcctccc tgaccatctc tggactcctg 60 gctgaggatg aggctgatta ttattgctgc tcatatgcag gcaggtacag tttcactatc 120 ttcggatct 129 <210> 1753 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1753 Asp Arg Leu Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Arg Tyr Ser Phe Thr Ile Phe Gly Ser 35 40 <210> 1754 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1754 gatcgcttat ctggctccaa gtctggcaac acggcctccc tgaccatctc tggactccag 60 gctgaggatg aggctgatta ttattgctgc tcatatgcag gcaggtacag tttcactatc 120 ttcggaact 129 <210> 1755 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1755 Asp Arg Leu Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Arg Tyr Ser Phe Thr Ile Phe Gly Thr 35 40 <210> 1756 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1756 gatcgcttat ctggctccaa gtctcgcaac acggcctccc tgaccatctc tggactccag 60 tctgaggatg aggctgatta ttattgctgc tcatatgcag gcaggtacag tttcactatc 120 ttcggaact 129 <210> 1757 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1757 Asp Arg Leu Ser Gly Ser Lys Ser Arg Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Arg Tyr Ser Phe Thr Ile Phe Gly Thr 35 40 <210> 1758 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1758 tgtaatcgct tctctggctc caagtctggc aacacggcct ccctgagaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactaaggtc 120 ttcggaact 129 <210> 1759 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1759 Cys Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Lys Val Phe Gly Thr 35 40 <210> 1760 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1760 tctaatcgct tctctggctc caagtctggc tacacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactaaggtc 120 ttcggaact 129 <210> 1761 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1761 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Lys Val Phe Gly Thr 35 40 <210> 1762 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1762 tctaatcgct tctctggctc caagtctggc atctcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactaaggtc 120 ttcggaact 129 <210> 1763 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1763 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Lys Val Phe Gly Thr 35 40 <210> 1764 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1764 tctaatcgct tctctggctc caagtctggc aagacggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactaaggtc 120 ttcggaact 129 <210> 1765 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1765 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Lys Val Phe Gly Thr 35 40 <210> 1766 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1766 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactaaggtc 120 ttcggaact 129 <210> 1767 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1767 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Lys Val Phe Gly Thr 35 40 <210> 1768 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1768 gatcgcttct ctggctccaa gtctggcatc tcggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgttgtc 120 ttcggaact 129 <210> 1769 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1769 Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Thr 35 40 <210> 1770 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1770 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgttgtc 120 ttcggaact 129 <210> 1771 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1771 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Thr 35 40 <210> 1772 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1772 ttccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgttgtc 120 ttcggaact 129 <210> 1773 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1773 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Thr 35 40 <210> 1774 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1774 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgttgtc 120 ttcggaact 129 <210> 1775 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1775 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Val Val Phe Gly Thr 35 40 <210> 1776 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1776 atacgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcgttgtc 120 ttcggaact 129 <210> 1777 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1777 ggggtccctg atcgcttctc tgtctccaag tctggcatca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagcgtggta 120 ttcggcgga 129 <210> 1778 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1778 Gly Val Pro Asp Arg Phe Ser Val Ser Lys Ser Gly Ile Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Gly Gly 35 40 <210> 1779 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1779 ggggtccctg atcgcttctc tggctccaag tctggcatca cggcctccct gaccatctct 60 gtgctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagcgtggta 120 ttcggcgga 129 <210> 1780 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1780 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Gly Gly 35 40 <210> 1781 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1781 ggggtccctg atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagcgtggta 120 ttcggcgga 129 <210> 1782 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1782 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Gly Gly 35 40 <210> 1783 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1783 ggggtccctg atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catacgcagg cagcgtggta 120 ttcgccgga 129 <210> 1784 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1784 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Ala Gly 35 40 <210> 1785 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1785 gggggacctg atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagcgtggta 120 ttcggcgga 129 <210> 1786 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1786 Gly Gly Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Val Val Phe Gly Gly 35 40 <210> 1787 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1787 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Leu Phe Val Phe 1 5 10 <210> 1788 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1788 cgcttctctg gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cctttttgtc 120 ttcggaact 129 <210> 1789 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1789 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Leu Phe Val Phe Gly Thr 35 40 <210> 1790 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1790 cgcttctctg gctccaagtc tggcaacaag gcctccctga ccatctctgt gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cctttttgtc 120 ttcggaact 129 <210> 1791 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1791 Arg Phe Ser Gly Ser Lys Ser Gly Asn Lys Ala Ser Leu Thr Ile Ser 1 5 10 15 Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Leu Phe Val Phe Gly Thr 35 40 <210> 1792 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1792 tcgcttctct ggctccaagt ctggcaacac ggcctcctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cctttttgtc 120 ttcggaact 129 <210> 1793 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1793 Ser Leu Leu Trp Leu Gln Val Trp Gln His Gly Leu Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Leu Phe Val Phe Gly Thr 35 40 <210> 1794 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1794 tcgcttctct ggctccaagt ctggcaacac ggcctccctg accatctctg ggctcaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cctttttgtc 120 ttcggaact 129 <210> 1795 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1795 Ser Leu Leu Trp Leu Gln Val Trp Gln His Gly Leu Pro Asp His Leu 1 5 10 15 Trp Ala Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Leu Phe Val Phe Gly Thr 35 40 <210> 1796 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1796 tcgcttctct ggctccaagt ctggcaacac ggcctccctg accatctctg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cctttttgtc 120 ttcggaact 129 <210> 1797 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1797 Ser Leu Leu Trp Leu Gln Val Trp Gln His Gly Leu Pro Asp His Leu 1 5 10 15 Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Leu Phe Val Phe Gly Thr 35 40 <210> 1798 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1798 Cys Ser Tyr Ala Gly Ser Tyr Thr Leu Val Val Phe 1 5 10 <210> 1799 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1799 gatcgcttct ctggctccaa gtctggctac acggcctccc agaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcttgtggta 120 ttcggcgga 129 <210> 1800 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1800 Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Gln Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Val Val Phe Gly Gly 35 40 <210> 1801 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1801 gatcgcttct ctggctccaa gtctggcatc acggcctccc tgtccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcttgtggta 120 ttcggcgga 129 <210> 1802 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1802 Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Val Val Phe Gly Gly 35 40 <210> 1803 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1803 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcttgtggta 120 ttcggcgga 129 <210> 1804 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1804 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Val Val Phe Gly Gly 35 40 <210> 1805 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1805 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatcac tgggctccag 60 gctgaggatg aggctgatta ttaccgctgc tcatatgcag gcagctacac tcttgtggta 120 ttcggcgga 129 <210> 1806 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1806 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Thr Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Arg Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Val Val Phe Gly Gly 35 40 <210> 1807 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1807 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tcttgtggta 120 ttcggcgga 129 <210> 1808 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1808 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Leu Val Val Phe Gly Gly 35 40 <210> 1809 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1809 Cys Ser Tyr Ala Gly Ser Ser Thr Ser Ser Val Phe 1 5 10 <210> 1810 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1810 aatcgcttct ctgtctccaa gtctggcaac acggcctccc tgactatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttccagtgtc 120 ttcggaact 129 <210> 1811 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1811 Asn Arg Phe Ser Val Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Ser Val Phe Gly Thr 35 40 <210> 1812 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1812 aatcgcttct ctggctccaa gtcttgcaac acggcctccc tgtcaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttccagtgtc 120 ttcggaact 129 <210> 1813 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1813 Asn Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Ser Val Phe Gly Thr 35 40 <210> 1814 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1814 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctggggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttccagtgtc 120 ttcggacct 129 <210> 1815 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1815 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Gly Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Ser Val Phe Gly Pro 35 40 <210> 1816 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1816 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttccagtgtc 120 ttcggaact 129 <210> 1817 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1817 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Ser Val Phe Gly Thr 35 40 <210> 1818 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1818 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttccagtgtc 120 ttcggaact 129 <210> 1819 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1819 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Ser Val Phe Gly Thr 35 40 <210> 1820 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1820 Cys Ser Tyr Ala Gly Thr Thr Thr Pro Phe Val Phe 1 5 10 <210> 1821 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1821 tatcgcttct ctggctccca gtctggcatc acggcctccc tgacaatctc tggtctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gcactaccac tccttttgtc 120 ttcggaact 129 <210> 1822 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1822 Tyr Arg Phe Ser Gly Ser Gln Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Thr Thr Thr Pro Phe Val Phe Gly Thr 35 40 <210> 1823 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1823 tatcgcttct ctggctccca gtctggcaac acggcctccc tgacaatctc ttgtctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gcactaccac tccttttgtc 120 ttcggaact 129 <210> 1824 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1824 Tyr Arg Phe Ser Gly Ser Gln Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Cys Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Thr Thr Thr Pro Phe Val Phe Gly Thr 35 40 <210> 1825 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1825 actcgcttct ctggctccca gtctggcatc acggcctccc tgacaatctc tggtctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gcactaccac tccttttgtc 120 ttcggaact 129 <210> 1826 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1826 Thr Arg Phe Ser Gly Ser Gln Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Thr Thr Thr Pro Phe Val Phe Gly Thr 35 40 <210> 1827 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1827 aatcgcttct ctggctccca gtctggcaac acggcctccc tgacaatctc tggtctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gcactaccac tccttttgtc 120 ttcggaact 129 <210> 1828 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1828 Asn Arg Phe Ser Gly Ser Gln Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Thr Thr Thr Pro Phe Val Phe Gly Thr 35 40 <210> 1829 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1829 aatcgattct ctggctccca gtctggcaac acggcatccc tgacaatctc tggtctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gcactaccac tccttttgtc 120 ttcggaact 129 <210> 1830 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1830 Cys Ser Tyr Ala Gly Ser Tyr Thr Ser Tyr Val Phe 1 5 10 <210> 1831 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1831 gatcgcttct ctggctgcaa gtctggcatc acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ctcttatgtc 120 ttcggaact 129 <210> 1832 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1832 Asp Arg Phe Ser Gly Cys Lys Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Tyr Val Phe Gly Thr 35 40 <210> 1833 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1833 gatcgcttct ctggctccaa gtcttgcaac acggcctccc tgaccatctc tgggctccag 60 gctgatgatg aggctgatta ttactgctgc tcatatgcag gcagctacac ctcttatgtc 120 ttcggaact 129 <210> 1834 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1834 Asp Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Tyr Val Phe Gly Thr 35 40 <210> 1835 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1835 gatcgcttct ctggctccaa gtctggcatc acggcctccc tgtccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ctcttatgtc 120 ttcggaact 129 <210> 1836 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1836 Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Tyr Val Phe Gly Thr 35 40 <210> 1837 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1837 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ctcttatgtc 120 ttcggaact 129 <210> 1838 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1838 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Ser Tyr Val Phe Gly Thr 35 40 <210> 1839 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1839 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ctcctatgtc 120 ttcggcact 129 <210> 1840 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1840 Cys Ser Tyr Ala Gly Ser Ser Ala Val Val Phe 1 5 10 <210> 1841 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1841 tctaatcgct tctctggctg caagtctggc aactcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cgctgtggta 120 ttcggcgga 129 <210> 1842 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1842 Ser Asn Arg Phe Ser Gly Cys Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ala Val Val Phe Gly Gly 35 40 <210> 1843 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1843 tctaatcgct tctctggctc catgtctggc aacacggcct ccctgacaat ctctcggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cgctgtggta 120 ttcggcgga 129 <210> 1844 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1844 Ser Asn Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Arg Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ala Val Val Phe Gly Gly 35 40 <210> 1845 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1845 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cgctgtggta 120 ttcggcgga 129 <210> 1846 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1846 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ala Val Val Phe Gly Gly 35 40 <210> 1847 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1847 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggccga ttattactgc tgctcgtatg caggtagtag cgctgtggta 120 ttcggcgga 129 <210> 1848 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1848 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cgctgtggta 120 ttcggcgga 129 <210> 1849 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1849 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ala Val Val Phe Gly Gly 35 40 <210> 1850 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1850 Cys Ser Tyr Thr Gly Ser Tyr Thr Leu Val Phe 1 5 10 <210> 1851 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1851 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatata caggcagcta cactttggta 120 ttcggcgga 129 <210> 1852 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1852 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 1853 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1853 cgtgatcgct tctctggctc caagtcttgc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatata caggcagcta cactttggta 120 ttcggcgga 129 <210> 1854 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1854 Arg Asp Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 1855 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1855 cctgatcgct tctctggctc gaagtctggc aacacggcct ccctgaccat ctctgggctc 60 ctggctgagg atgaggctga ttattactgc tgctcatata caggcagcta cactttggta 120 ttcggcgga 129 <210> 1856 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1856 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 1857 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1857 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgtgctc 60 caggctgagg atgaggctga ttattactgc tgctcatata caggcagcta caccttggta 120 ttcggcgga 129 <210> 1858 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1858 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 1859 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1859 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatata caggcagcta cactttggta 120 ttcggcgga 129 <210> 1860 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1860 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Gly Ser Tyr Thr Leu Val Phe Gly Gly 35 40 <210> 1861 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1861 gtttcttata gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tctttatgtc 120 ttcggaact 129 <210> 1862 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1862 Val Ser Tyr Ser Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Leu Tyr Val Phe Gly Thr 35 40 <210> 1863 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1863 gtttctactc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctgtg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tctttatgtc 120 ttcggaact 129 <210> 1864 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1864 Val Ser Thr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Leu Tyr Val Phe Gly Thr 35 40 <210> 1865 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1865 gtttctaatc gcttctctgg ctccaagtct tgcaacacgg cctccctgac tatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tctttatgtc 120 ttcggaact 129 <210> 1866 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1866 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Leu Tyr Val Phe Gly Thr 35 40 <210> 1867 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1867 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tctttatgtc 120 ttcggaact 129 <210> 1868 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1868 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Leu Tyr Val Phe Gly Thr 35 40 <210> 1869 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1869 gttctaatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tctttatgtc 120 ttcggaact 129 <210> 1870 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1870 Val Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Leu Tyr Val Phe Gly Thr 35 40 <210> 1871 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1871 Cys Ser Tyr Ala Gly Ser Tyr Val Phe 1 5 <210> 1872 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1872 gggtccctga tccgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagctacgta 120 ttcggcgga 129 <210> 1873 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1873 Gly Ser Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Tyr Val Phe Gly Gly 35 40 <210> 1874 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1874 ggggtccctg atcgcttctc tggctccaag tctggcatca cggcctccct gaccatctct 60 gtgctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagctacgta 120 ttcggcgga 129 <210> 1875 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1875 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Tyr Val Phe Gly Gly 35 40 <210> 1876 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1876 ggggtccctg atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctcgagg ctgaggatga ggctgattat tactgctgct catatgcagg cagctacgta 120 ttcggcggt 129 <210> 1877 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1877 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Tyr Val Phe Gly Gly 35 40 <210> 1878 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1878 ggggtccctg atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagctacgta 120 ttcggcgga 129 <210> 1879 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1879 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Tyr Val Phe Gly Gly 35 40 <210> 1880 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1880 ggggtccctg atcgcttctc tggctccaag tccggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcggg cagctacgta 120 ttcggcgga 129 <210> 1881 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1881 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Tyr Val Phe 1 5 10 <210> 1882 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1882 gatcgcttct ctggctccaa gtctggctac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta tttctgctgc tcatatgcag gcagctacac tttttatgtc 120 ttcggaact 129 <210> 1883 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1883 Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 1884 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1884 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttttatgtc 120 ttcggaact 129 <210> 1885 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1885 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 1886 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1886 gatcgcttct ctggctccaa gtctgacaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac cttttatgtc 120 ttcggaact 129 <210> 1887 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1887 Asp Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 1888 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1888 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttttatgtc 120 ttcggaact 129 <210> 1889 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1889 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 1890 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1890 atacgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttttatgtc 120 ttcggaact 129 <210> 1891 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1891 Cys Ser Tyr Ala Gly Thr Tyr Thr Trp Val Phe 1 5 10 <210> 1892 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1892 ctgattcgct tctctggctc caagtctggc aacacggcct ccctgaccct ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta cacttgggtg 120 ttcggcgga 129 <210> 1893 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1893 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 1894 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1894 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccct ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta cacttgggtg 120 ttcggcgga 129 <210> 1895 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1895 cctgatcgct tctctggctc caagtctggc tacacggcct ccctgacgct ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta cacttgggtg 120 ttcggcgga 129 <210> 1896 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1896 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 1897 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1897 cctgatcgct tctctggctc caagtctggc aacacggcct cccttaccct ctctgggctc 60 caggctgagg atgaggatga ttattactgc tgctcatatg caggcaccta cacttgggtg 120 ttcggcgga 129 <210> 1898 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1898 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Asp Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 1899 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1899 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccct ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta cacttgggtg 120 ttcggcgga 129 <210> 1900 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1900 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Leu Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Thr Trp Val Phe Gly Gly 35 40 <210> 1901 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1901 Cys Ser Tyr Ala Gly Ser Ser Thr Leu Val Val Phe 1 5 10 <210> 1902 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1902 tttcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttagtggta 120 ttcggcgga 129 <210> 1903 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1903 Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Leu Val Val Phe Gly Gly 35 40 <210> 1904 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1904 aatcgcttct ctggctccaa gtctggcttc acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttggtggta 120 ttcggcgga 129 <210> 1905 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1905 Asn Arg Phe Ser Gly Ser Lys Ser Gly Phe Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Leu Val Val Phe Gly Gly 35 40 <210> 1906 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1906 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttggtggta 120 ttcggcgga 129 <210> 1907 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1907 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Leu Val Val Phe Gly Gly 35 40 <210> 1908 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1908 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttagtggta 120 ttcggcgga 129 <210> 1909 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1909 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttggtggta 120 ttcggcgga 129 <210> 1910 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1910 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Leu Val Val Phe Gly Gly 35 40 <210> 1911 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1911 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Gly Ser Val Phe 1 5 10 <210> 1912 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1912 cgcttctctg gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct 60 gagtatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cggtagtgtc 120 ttcgtaact 129 <210> 1913 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1913 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Tyr Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Gly Ser Val Phe Val Thr 35 40 <210> 1914 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1914 cgcttctctg gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cggtagtgtc 120 ttcggaact 129 <210> 1915 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1915 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Gly Ser Val Phe Gly Thr 35 40 <210> 1916 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1916 agcttctctg gctccaagtc tggcatcacg gcctccctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cggtagtgtc 120 ttcggaact 129 <210> 1917 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1917 Ser Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Gly Ser Val Phe Gly Thr 35 40 <210> 1918 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1918 tcgcttctct ggctccaagt ctggcaacac ggcctcctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cggtagtgtc 120 ttcggaact 129 <210> 1919 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1919 Ser Leu Leu Trp Leu Gln Val Trp Gln His Gly Leu Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Gly Ser Val Phe Gly Thr 35 40 <210> 1920 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1920 Cys Ser Tyr Ser Gly Arg Tyr Thr Tyr Val Phe 1 5 10 <210> 1921 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1921 cctgttcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 ctggctgaag atgaggctga ttatttctgc tgctcatatt caggcaggta cacttatgtc 120 ttcggaact 129 <210> 1922 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1922 Pro Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ser Gly Arg Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 1923 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1923 cctgatcgct tctctggctc caagtctggc aacacggcct ccctggccat ctctgggctc 60 caggctgaag atgaggctga ttatttctgc tgctcgtatt caggcaggta cacttatgtc 120 ttcggaact 129 <210> 1924 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1924 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ser Gly Arg Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 1925 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1925 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgaag atgaggctga ttatttctgc tgctcatatt caggcaggta cacttatgtc 120 ttcggaact 129 <210> 1926 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1926 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ser Gly Arg Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 1927 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1927 cctgatcgct tctctggcta caagtctgtc aacacggcct ccctgaccat ctctgggctc 60 caggctgaag atgaggctga ttatttctgc tgctcatatt caggcaggta cacttatgtc 120 ttcggaact 129 <210> 1928 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1928 Pro Asp Arg Phe Ser Gly Tyr Lys Ser Val Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ser Gly Arg Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 1929 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1929 Cys Ser Tyr Ala Gly Ser Arg Thr Phe Val Phe 1 5 10 <210> 1930 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1930 tctaatcgct tctctggctc caagtctggc atctcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag aacttttgtc 120 ttcggaact 129 <210> 1931 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1931 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Thr Phe Val Phe Gly Thr 35 40 <210> 1932 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1932 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggttga ttattactgc tgctcatatg caggcagtag aacttttgtc 120 ttcggaact 129 <210> 1933 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1933 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Val Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Thr Phe Val Phe Gly Thr 35 40 <210> 1934 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1934 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag aacttttgtc 120 ttcggaact 129 <210> 1935 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1935 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Thr Phe Val Phe Gly Thr 35 40 <210> 1936 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1936 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag aacttttgtc 120 ttcggaact 129 <210> 1937 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1937 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Thr Phe Val Phe Gly Thr 35 40 <210> 1938 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1938 Cys Ser Tyr Ala Gly Ser Ser Thr Tyr Tyr Val Phe 1 5 10 <210> 1939 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1939 aatcgcttct ctggctccaa gtctggcgac acggtctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ctattatgtc 120 ttcggaact 129 <210> 1940 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1940 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asp Thr Val Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Tyr Val Phe Gly Thr 35 40 <210> 1941 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1941 aatcgcttct ctggctccaa gtctggcaag actgcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ctattatgtc 120 ttcggaact 129 <210> 1942 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1942 Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Tyr Val Phe Gly Thr 35 40 <210> 1943 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1943 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ctattatgtc 120 ttcggaact 129 <210> 1944 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1944 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Tyr Val Phe Gly Thr 35 40 <210> 1945 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1945 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ctattatgtc 120 ttcggaact 129 <210> 1946 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1946 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Tyr Tyr Val Phe Gly Thr 35 40 <210> 1947 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1947 Cys Ser Tyr Ala Gly Ser Ser Thr Val Leu Phe 1 5 10 <210> 1948 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1948 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtgcta 120 ttcggcgga 129 <210> 1949 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1949 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Leu Phe Gly Gly 35 40 <210> 1950 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1950 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg gcgaggctga ttattactgc tgctcatatg caggtagtag cactgtgcta 120 ttcggcgga 129 <210> 1951 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1951 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Gly Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Leu Phe Gly Gly 35 40 <210> 1952 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1952 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtgcta 120 ttcggcgga 129 <210> 1953 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1953 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Leu Phe Gly Gly 35 40 <210> 1954 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1954 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtgcta 120 ttcggcgca 129 <210> 1955 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1955 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Leu Phe Gly Ala 35 40 <210> 1956 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1956 Cys Ser Tyr Ala Gly Ser Tyr Thr Leu Leu Phe 1 5 10 <210> 1957 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1957 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 cgggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactctgcta 120 ttcggcgga 129 <210> 1958 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1958 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Arg Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Leu Phe Gly Gly 35 40 <210> 1959 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1959 cctgatcgct tctctggctc catgtctggc aacacggcct ccctgacctt ctctgggctc 60 cgggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactctgcta 120 ttcggcgga 129 <210> 1960 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1960 Pro Asp Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Arg Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Leu Phe Gly Gly 35 40 <210> 1961 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1961 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctggtctc 60 cgggctgagg atgagtctga ttattactgc tgctcatatg caggcagcta cactctgcta 120 ttcggcgga 129 <210> 1962 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1962 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Arg Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Leu Phe Gly Gly 35 40 <210> 1963 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1963 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 cgggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactctgcta 120 ttcggcgga 129 <210> 1964 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1964 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Arg Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Leu Leu Phe Gly Gly 35 40 <210> 1965 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1965 Cys Ser Tyr Ala Gly Ser Ser Thr Leu Glu Phe 1 5 10 <210> 1966 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1966 ttctatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagag 120 ttcggcgga 129 <210> 1967 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1967 Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Glu Phe Gly Gly 35 40 <210> 1968 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1968 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagag 120 ttcggcgga 129 <210> 1969 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1969 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Glu Phe Gly Gly 35 40 <210> 1970 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1970 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagag 120 ttcggcgga 129 <210> 1971 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1971 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Glu Phe Gly Gly 35 40 <210> 1972 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1972 ctaatacgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttagag 120 ttcggcgga 129 <210> 1973 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1973 Cys Ser Tyr Ala Gly Gly Ser Val Val Phe 1 5 10 <210> 1974 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1974 tttcttatcc gcttctctgg ctccaagtct ggcaacacag cctccctgac aatctctggg 60 atccaggctg aggacgaggc tgattattat tgttgttcat atgcaggtgg tagcgtggta 120 ttcggcgga 129 <210> 1975 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1975 Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Ile Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Gly Ser Val Val Phe Gly Gly 35 40 <210> 1976 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1976 gtttcttatc gcttctctgg ctccaagtct ggcaacacag cctgcctgac aatctctggg 60 atccaggctg aggacgaggc tgattattat tgttgttcat atgcaggtgg tagcgtggta 120 ttcggcgga 129 <210> 1977 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1977 Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Cys Leu 1 5 10 15 Thr Ile Ser Gly Ile Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Gly Ser Val Val Phe Gly Gly 35 40 <210> 1978 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1978 gtttctaatc gcttctctgg ctccaagtct ggcaacacag cctccctgac aatctcttgg 60 atgcaggctg aggacgaggc tgattattat tgttgttcat atgcaggtgg tagcgtggta 120 ttcggcgga 129 <210> 1979 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1979 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Trp Met Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Gly Ser Val Val Phe Gly Gly 35 40 <210> 1980 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1980 gtttctaatc gcttctctgg ctccaagtct ggcaacacag cctccctgac aatctctggg 60 atccaggctg aggacgaggc tgattattat tgttgttcat atgcaggtgg tagcgtggta 120 ttcggcgga 129 <210> 1981 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1981 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Ile Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Gly Ser Val Val Phe Gly Gly 35 40 <210> 1982 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1982 Cys Ser Tyr Ala Asp Ser Ser Thr Phe Tyr Val Phe 1 5 10 <210> 1983 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1983 aatcgcttct ctggctccat gtctggcaac acggcctccc tgacaatctc tgggctgcag 60 gctgaggacg aggctgatta ttactgttgc tcatatgcag atagtagcac tttctatgtc 120 ttcggaact 129 <210> 1984 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1984 Asn Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Asp Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 1985 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1985 aatcgcttct ctggctccaa gtctgtcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg agtctgatta ttactgttgc tcatatgcag atagtagcac tttctatgtc 120 ttcggaact 129 <210> 1986 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1986 Asn Arg Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Asp Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 1987 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1987 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgttgc tcatatgcag atagtagcac tttctatgtc 120 ttcggaact 129 <210> 1988 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1988 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Asp Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 1989 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1989 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgttgc tcatatgcag atagtagcac tttctatgtc 120 ttcggaact 129 <210> 1990 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1990 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Asp Ser Ser Thr Phe Tyr Val Phe Gly Thr 35 40 <210> 1991 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1991 tcttatcgct tctctggctc caagtctggc atcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag tactgtggtt 120 tttggcgga 129 <210> 1992 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1992 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 1993 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1993 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgactat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag tactgtggtt 120 tttggcgga 129 <210> 1994 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1994 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Val Val Phe Gly Gly 35 40 <210> 1995 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1995 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag tactgtggtt 120 tttggcgga 129 <210> 1996 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1996 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactgtggtt 120 ttcggcggt 129 <210> 1997 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1997 Cys Ser Tyr Ala Gly Ser Ser Ile Val Phe 1 5 10 <210> 1998 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1998 tttctaatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcatcgta 120 ttcggcgga 129 <210> 1999 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 1999 Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Ile Val Phe Gly Gly 35 40 <210> 2000 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2000 gtttcttatc gcttctctgg ctccaagtct ggcaactcgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcatcgta 120 ttcggcgga 129 <210> 2001 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2001 Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Ile Val Phe Gly Gly 35 40 <210> 2002 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2002 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac tatctctggg 60 ctccaggctg aggtcgaggc tgattattac tgctgctcat atgcaggtag tagcatcgta 120 ttcggcgga 129 <210> 2003 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2003 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Val Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Ile Val Phe Gly Gly 35 40 <210> 2004 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2004 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcatcgta 120 ttcggcgga 129 <210> 2005 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2005 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Ile Val Phe Gly Gly 35 40 <210> 2006 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2006 Cys Ser Tyr Ala Gly Arg Asp Thr Tyr Val Ala Phe 1 5 10 <210> 2007 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2007 gttcggttct ttggctccaa gtctggcaac tcggcctccc tgaccttctc tgggctccag 60 gctgaggatg aagctgatta ttactgctgc tcatatgcag gcagggacac ttatgtggca 120 ttcggcgga 129 <210> 2008 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2008 Val Arg Phe Phe Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Phe 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Arg Asp Thr Tyr Val Ala Phe Gly Gly 35 40 <210> 2009 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2009 gatcggttct ttggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aagctgatta ttactgctgc tcatatgcag gcagggacac ttatgtggca 120 ttcggcgga 129 <210> 2010 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2010 Asp Arg Phe Phe Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Arg Asp Thr Tyr Val Ala Phe Gly Gly 35 40 <210> 2011 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2011 gatcggttcg ttggctccaa gtctggcaac acggcctccc cgaccatctc tgggctccag 60 gctgaggatg aagctgatta ttactgctgc tcatatgcag gcagggacac ttatgtggca 120 ttcggcgga 129 <210> 2012 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2012 Asp Arg Phe Val Gly Ser Lys Ser Gly Asn Thr Ala Ser Pro Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Arg Asp Thr Tyr Val Ala Phe Gly Gly 35 40 <210> 2013 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2013 gatcggtcct ttggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgagtatg aagctgatta ttactgctgc tcatatgcag gcagggacac ttatgtggca 120 ttcggcgga 129 <210> 2014 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2014 Asp Arg Ser Phe Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Tyr Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Arg Asp Thr Tyr Val Ala Phe Gly Gly 35 40 <210> 2015 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2015 Cys Ser Tyr Ala Gly Ser Tyr Thr Val Phe 1 5 10 <210> 2016 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2016 gtccctgttc gcttctctgg ctccaagtct ggctacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacacggta 120 ttcggcgga 129 <210> 2017 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2017 Val Pro Val Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Thr Val Phe Gly Gly 35 40 <210> 2018 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2018 gtccctgttc gcttctctgg ctccaagtct ggcaacacgg cctccccgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacacggta 120 ttcggcgga 129 <210> 2019 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2019 Val Pro Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Pro 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Thr Val Phe Gly Gly 35 40 <210> 2020 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2020 gtccctgatc gcttctctgg ctccaagtct ggcatcacgg cctccctgac catctcttgg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacacggta 120 ttcggcgga 129 <210> 2021 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2021 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Thr Val Phe Gly Gly 35 40 <210> 2022 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2022 gtccctgatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacacggta 120 ttcggcgga 129 <210> 2023 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2023 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Thr Val Phe Gly Gly 35 40 <210> 2024 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2024 Cys Ser Tyr Ala Gly Ser Tyr Ile Pro Val Val Phe 1 5 10 <210> 2025 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2025 gttcgcttct ctggctccaa gtctggcaac tcggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacat tcctgtggta 120 ttcggcgga 129 <210> 2026 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2026 Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ile Pro Val Val Phe Gly Gly 35 40 <210> 2027 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2027 gatcgcttct ctggctgcaa gtctggcaac tcggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacat tcctgtggta 120 ttcggcgga 129 <210> 2028 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2028 Asp Arg Phe Ser Gly Cys Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ile Pro Val Val Phe Gly Gly 35 40 <210> 2029 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2029 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgtccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacat tcctgtggta 120 ttcggcggt 129 <210> 2030 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2030 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ile Pro Val Val Phe Gly Gly 35 40 <210> 2031 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2031 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacat tcctgtggta 120 ttcggcgga 129 <210> 2032 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2032 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ile Pro Val Val Phe Gly Gly 35 40 <210> 2033 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2033 Cys Ser Tyr Ala Gly Arg Tyr Thr Leu Val Phe 1 5 10 <210> 2034 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2034 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaggta cactttggta 120 ttcggcgta 129 <210> 2035 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2035 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Arg Tyr Thr Leu Val Phe Gly Val 35 40 <210> 2036 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2036 cctgatcgct tctctggctc caagtcttgc aacacggcct ccctgaccat ctctgggctc 60 gaggctgagg atgaggctga ttattactgc tgctcatatg caggcaggta cactttggta 120 ttcggcgta 129 <210> 2037 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2037 Pro Asp Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Arg Tyr Thr Leu Val Phe Gly Val 35 40 <210> 2038 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2038 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctcttggctc 60 cagtctgagg atgaggctga ttattactgc tgctcatatg caggcaggta cactttggta 120 ttcggcgta 129 <210> 2039 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2039 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Arg Tyr Thr Leu Val Phe Gly Val 35 40 <210> 2040 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2040 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaggta cactttggta 120 ttcggcgta 129 <210> 2041 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2041 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Arg Tyr Thr Leu Val Phe Gly Val 35 40 <210> 2042 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2042 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Leu Phe 1 5 10 <210> 2043 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2043 tcttttcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttttta 120 ttcggcgga 129 <210> 2044 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2044 Ser Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Leu Phe Gly Gly 35 40 <210> 2045 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2045 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttttta 120 ttcggcgga 129 <210> 2046 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2046 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Leu Phe Gly Gly 35 40 <210> 2047 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2047 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttccta 120 ttcggcgga 129 <210> 2048 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2048 tctaatcgat tctctggctc caagtctggc aacactgcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttttta 120 ttcggcgga 129 <210> 2049 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2049 Cys Ser Tyr Ala Gly Ser Ser Thr Ser Val Leu Phe 1 5 10 <210> 2050 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2050 attcgcttct ctggctccaa gtctggcatc acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttccgtgttg 120 ttcggcgga 129 <210> 2051 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2051 Ile Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Val Leu Phe Gly Gly 35 40 <210> 2052 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2052 attcgcttct ctggctccaa gtctggcaac actgcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttccgtgttg 120 ttcggcgga 129 <210> 2053 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2053 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Val Leu Phe Gly Gly 35 40 <210> 2054 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2054 aatcgcttct ctggctgcaa gtctggcacc acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttccgtgttg 120 ttcggcgga 129 <210> 2055 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2055 Asn Arg Phe Ser Gly Cys Lys Ser Gly Thr Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Val Leu Phe Gly Gly 35 40 <210> 2056 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2056 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttccgtgttg 120 ttcggcgga 129 <210> 2057 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2057 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Val Leu Phe Gly Gly 35 40 <210> 2058 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2058 Cys Ala Phe Thr Gly Ser Tyr Glu Val Phe 1 5 10 <210> 2059 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2059 tgcctgatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac tatctctggg 60 ctccaggctg aggatgaggc tgattattat tgctgcgcgt ttacaggcag ctacgaggtg 120 ttcggcgga 129 <210> 2060 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2060 Cys Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ala Phe Thr Gly Ser Tyr Glu Val Phe Gly Gly 35 40 <210> 2061 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2061 gtccctgatc gcttctctgg ctccaagtct ggcatctcgg cctccctgac tatctctggg 60 ctccaggctg aggatgaggc tgattattat tgctgcgcgt ttacaggcag ctacgaggtg 120 ttcggcgga 129 <210> 2062 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2062 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ala Phe Thr Gly Ser Tyr Glu Val Phe Gly Gly 35 40 <210> 2063 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2063 gtccctgatc gcttctctgg ctccaagtct ggcaacacgg cctccctgtc tatctctggg 60 ctcgaggctg aggatgaggc tgattattat tgctgcgcgt ttacaggcag ctacgaggtg 120 ttcggcgga 129 <210> 2064 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2064 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Ser Ile Ser Gly Leu Glu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ala Phe Thr Gly Ser Tyr Glu Val Phe Gly Gly 35 40 <210> 2065 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2065 gtccctgatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac tatctctggg 60 ctccaggctg aggatgaggc tgattattat tgctgcgcgt ttacaggcag ctacgaggtg 120 ttcggcgga 129 <210> 2066 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2066 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ala Phe Thr Gly Ser Tyr Glu Val Phe Gly Gly 35 40 <210> 2067 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2067 Cys Ser Tyr Ala Gly Ser Gly Thr Cys Val Phe 1 5 10 <210> 2068 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2068 tctattcgct tctccggctc caagtctggc aactcggcct ccctgacaat ctctgggctc 60 cgggctgagg acgaggctga ttattactgc tgctcatatg caggtagtgg cacctgcgtg 120 ttcggcgga 129 <210> 2069 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2069 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Arg Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Gly Thr Cys Val Phe Gly Gly 35 40 <210> 2070 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2070 tctattcgct tctccggctc caagtctggc aacacggcct ccctgagaat ctctgggctc 60 cgggctgagg acgaggctga ttattactgc tgctcatatg caggtagtgg cacctgcgtg 120 ttcggcgga 129 <210> 2071 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2071 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Arg 1 5 10 15 Ile Ser Gly Leu Arg Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Gly Thr Cys Val Phe Gly Gly 35 40 <210> 2072 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2072 tctaatcgct tctccggctc caagtctggg aactcggcct ccctgacaat ctctgggctc 60 cgggctgagg acgaggctga ttattactgc tgctcatatg caggtagtgg cacctgcgtg 120 ttcggcgga 129 <210> 2073 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2073 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Arg Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Gly Thr Cys Val Phe Gly Gly 35 40 <210> 2074 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2074 tctaatcgct tctccggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 cgggctgagg acgaggctga ttattactgc tgctcatatg caggtagtgg cacctgcgtg 120 ttcggcgga 129 <210> 2075 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2075 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Arg Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Gly Thr Cys Val Phe Gly Gly 35 40 <210> 2076 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2076 Cys Ser Tyr Ala Gly Ser Tyr Thr Leu Ser Val Val Phe 1 5 10 <210> 2077 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2077 cgcttctctg gctccaagtc tggcaactcg gcctccctga ccatctctgg gctcctggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt aagtgtggta 120 ttcggcgga 129 <210> 2078 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2078 Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Leu Ser Val Val Phe Gly Gly 35 40 <210> 2079 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2079 cgcttctctg gctccaagtc tggcaacacg gcctccctga ccgtctctgg gctccaggct 60 gaggatgggg ctgattatta ctgctgctca tatgcaggca gctacacttt aagtgtggta 120 ttcggcgga 129 <210> 2080 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2080 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Val Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Gly Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Leu Ser Val Val Phe Gly Gly 35 40 <210> 2081 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2081 cgcttctctg gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt aagtgtggta 120 ttcggcgga 129 <210> 2082 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2082 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Leu Ser Val Val Phe Gly Gly 35 40 <210> 2083 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2083 tcgcttctct ggctccaagt ctggcaacac ggcctccctg accatctctg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt aagtgtggta 120 ttcggcgga 129 <210> 2084 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2084 Ser Leu Leu Trp Leu Gln Val Trp Gln His Gly Leu Pro Asp His Leu 1 5 10 15 Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Leu Ser Val Val Phe Gly Gly 35 40 <210> 2085 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2085 Cys Ser Tyr Ala Ala Ser Tyr Thr Val Val Phe 1 5 10 <210> 2086 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2086 cctgatcgct tctctggctc caagtctggc atcacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg cagccagcta caccgttgta 120 ttcggcgga 129 <210> 2087 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2087 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Ala Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 2088 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2088 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg cagccagcta caccgtggta 120 ttcggcgga 129 <210> 2089 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2089 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Ala Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 2090 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2090 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaagctga ttactactgc tgctcatatg cagccagcta caccgtggta 120 ttcggcgga 129 <210> 2091 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2091 cctgatcgct tctctggcgc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg cagccagtta caccgtggta 120 ttcggcgga 129 <210> 2092 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2092 Pro Asp Arg Phe Ser Gly Ala Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Ala Ser Tyr Thr Val Val Phe Gly Gly 35 40 <210> 2093 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2093 Cys Ser Tyr Ala Gly Ser Tyr Thr Tyr Tyr Val Phe 1 5 10 <210> 2094 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2094 gatcgcttct ctggctccat gtctggcaac acggcctccc tgaccatctc ttggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ctattatgtc 120 ttcggaact 129 <210> 2095 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2095 Asp Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Tyr Tyr Val Phe Gly Thr 35 40 <210> 2096 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2096 gatcgcttct ctggctccaa gtctggcatc acggcctccc tgacgatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ctattatgtc 120 ttcggaact 129 <210> 2097 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2097 Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Tyr Tyr Val Phe Gly Thr 35 40 <210> 2098 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2098 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ctattatgtc 120 ttcggaact 129 <210> 2099 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2099 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Tyr Tyr Val Phe Gly Thr 35 40 <210> 2100 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2100 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ctattatgtc 120 ttcggaact 129 <210> 2101 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2101 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Tyr Tyr Val Phe Gly Thr 35 40 <210> 2102 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2102 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Pro Val Val Phe 1 5 10 <210> 2103 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2103 cgcttctctg tctccaagtc tgtcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt ccctgtggta 120 ttcggcgga 129 <210> 2104 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2104 Arg Phe Ser Val Ser Lys Ser Val Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Pro Val Val Phe Gly Gly 35 40 <210> 2105 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2105 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt ccctgtggta 120 ttcggcgga 129 <210> 2106 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2106 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Pro Val Val Phe Gly Gly 35 40 <210> 2107 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2107 cgcttccctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt ccctgtggta 120 ttcggccga 129 <210> 2108 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2108 Arg Phe Pro Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Pro Val Val Phe Gly Arg 35 40 <210> 2109 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2109 tcgcttctct gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt ccctgtggta 120 ttcggcgga 129 <210> 2110 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2110 Ser Leu Leu Cys Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Pro Val Val Phe Gly Gly 35 40 <210> 2111 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2111 Cys Ser Tyr Ala Gly Pro Ser Thr Leu Val Phe 1 5 10 <210> 2112 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2112 tcttatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 ctggctgaag acgaggctga ttattactgc tgctcatatg caggtcctag cactttggtt 120 ttcggcgga 129 <210> 2113 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2113 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Pro Ser Thr Leu Val Phe Gly Gly 35 40 <210> 2114 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2114 tctattcgct tctctggctc caagtctggc aactcggcct ccctgacaat ctctgggctc 60 caggctgaag acgaggctga ttattactgc tgctcatatg caggtcctag cactttggtt 120 ttcggcgga 129 <210> 2115 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2115 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Pro Ser Thr Leu Val Phe Gly Gly 35 40 <210> 2116 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2116 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgactat ctctgggctc 60 caggctgaag acgaggctga ttattactgc tgctcatatg caggtcctag cactttggtt 120 ttcggcgga 129 <210> 2117 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2117 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Pro Ser Thr Leu Val Phe Gly Gly 35 40 <210> 2118 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2118 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgaag acgaggctga ttattactgc tgctcatatg caggtcctag cactttggtt 120 ttcggcgga 129 <210> 2119 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2119 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Pro Ser Thr Leu Val Phe Gly Gly 35 40 <210> 2120 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2120 Cys Ser Tyr Ala Gly Ser Pro Tyr Val Phe 1 5 10 <210> 2121 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2121 tttctaatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tccttatgtc 120 ttcggaact 129 <210> 2122 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2122 Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Pro Tyr Val Phe Gly Thr 35 40 <210> 2123 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2123 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tccttatgtc 120 ttcggaact 129 <210> 2124 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2124 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Pro Tyr Val Phe Gly Thr 35 40 <210> 2125 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2125 gttctaatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tccttatgtc 120 ttcggaact 129 <210> 2126 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2126 Val Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Pro Tyr Val Phe Gly Thr 35 40 <210> 2127 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2127 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggcag tccttatgtc 120 ttcggaact 129 <210> 2128 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2128 Cys Ser Tyr Ala Gly Ser Tyr Ser Trp Val Phe 1 5 10 <210> 2129 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2129 cctgatcgct tctctggctc caagtctggc atctcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcctgggtg 120 ttcggcgga 129 <210> 2130 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2130 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Trp Val Phe Gly Gly 35 40 <210> 2131 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2131 cctgatcgct tctctggctc caagtctggc agcatggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcctgggtg 120 ttcggcgga 129 <210> 2132 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2132 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ser Met Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Trp Val Phe Gly Gly 35 40 <210> 2133 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2133 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcctgggtg 120 ttcggcgga 129 <210> 2134 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2134 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Trp Val Phe Gly Gly 35 40 <210> 2135 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2135 cctgaccgct tctctggctc caagtctgac aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctcctgggtg 120 ttcggcgga 129 <210> 2136 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2136 Pro Asp Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Trp Val Phe Gly Gly 35 40 <210> 2137 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2137 Cys Ser Tyr Ala Gly Asp Ser Phe Pro Tyr Val Phe 1 5 10 <210> 2138 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2138 aatcgcttct ctggctccat gtctggcatc acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtgatagctt cccttatgtc 120 ttcggaact 129 <210> 2139 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2139 Asn Arg Phe Ser Gly Ser Met Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Asp Ser Phe Pro Tyr Val Phe Gly Thr 35 40 <210> 2140 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2140 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtgatagctt cccttatgtc 120 ttcggaact 129 <210> 2141 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2141 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Asp Ser Phe Pro Tyr Val Phe Gly Thr 35 40 <210> 2142 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2142 aatcgattct ctggctccaa gtctggaaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtgatagctt cccttatgtc 120 ttcggaact 129 <210> 2143 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2143 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtgatagctt cccttatgtc 120 ttcggaact 129 <210> 2144 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2144 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Asp Ser Phe Pro Tyr Val Phe Gly Thr 35 40 <210> 2145 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2145 Cys Ser Tyr Ala Gly Ser Thr Thr Phe Val Leu Phe 1 5 10 <210> 2146 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2146 tatcgcttct ctggctccaa gtctggcatc acggcctccc tgaaattctc tggactccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtaccac tttcgttcta 120 ttcggcgga 129 <210> 2147 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2147 Tyr Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Lys Phe 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Thr Thr Phe Val Leu Phe Gly Gly 35 40 <210> 2148 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2148 tatcgcttct ctggctccaa gtctggcaac acggcctccc tgaaaatctc tggactccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtaccac tttcgttcta 120 ttcggcgga 129 <210> 2149 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2149 Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Lys Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Thr Thr Phe Val Leu Phe Gly Gly 35 40 <210> 2150 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2150 tatcgattct ctggctccaa gtctggcaac acggcctccc tgataatctc tggactccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtaccac tttcgttcta 120 ttcggcgga 129 <210> 2151 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2151 Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ile Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Thr Thr Phe Val Leu Phe Gly Gly 35 40 <210> 2152 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2152 atacgcttct ctggctccaa gtctggcaac acggcctccc tgaaaatctc tggactccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtaccac tttcgttcta 120 ttcggcgga 129 <210> 2153 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2153 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Lys Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Thr Thr Phe Val Leu Phe Gly Gly 35 40 <210> 2154 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2154 Cys Ser Tyr Ala Gly Ser Tyr Thr Leu Phe 1 5 10 <210> 2155 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2155 gtccctgatc gcttctctgg ctccaagtct ggctacacgg cctccctgac gatctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacacttta 120 ttcggcgga 129 <210> 2156 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2156 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Thr Leu Phe Gly Gly 35 40 <210> 2157 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2157 gtccctgatc gcttctctgg ctccaagtct ggcatcacgg cctccctgac catctctggg 60 ctccagtctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacacttta 120 ttcggcgga 129 <210> 2158 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2158 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Thr Leu Phe Gly Gly 35 40 <210> 2159 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2159 gtccctgatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac catctcttgg 60 ctccagtctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacacttta 120 ttcggcgga 129 <210> 2160 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2160 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Trp Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Thr Leu Phe Gly Gly 35 40 <210> 2161 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2161 gtccctgatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctacacttta 120 ttcggcgga 129 <210> 2162 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2162 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Tyr Thr Leu Phe Gly Gly 35 40 <210> 2163 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2163 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Glu Val Phe 1 5 10 <210> 2164 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2164 tatcgcttct ctggctccaa gtctggcatc acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgaggtc 120 ttcggaact 129 <210> 2165 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2165 Tyr Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Glu Val Phe Gly Thr 35 40 <210> 2166 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2166 aatcgcttct ctggctccaa gtctggcaag acggcctgcc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgaggtc 120 ttcggaact 129 <210> 2167 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2167 Asn Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Cys Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Glu Val Phe Gly Thr 35 40 <210> 2168 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2168 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagtac tttcgaagtc 120 ttcggaact 129 <210> 2169 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2169 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Glu Val Phe Gly Thr 35 40 <210> 2170 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2170 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgaggtc 120 ttcggaact 129 <210> 2171 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2171 Cys Ser Tyr Ala Gly Thr Tyr Thr Tyr Val Phe 1 5 10 <210> 2172 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2172 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta cacttacgtc 120 ttcggaact 129 <210> 2173 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2173 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 2174 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2174 cctgatcgct tctctggctc caagtctggc tacacggcct ccctgaccat ctctgtgctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta cacttacgtc 120 ttcggaact 129 <210> 2175 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2175 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 2176 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2176 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta cacttacgtc 120 ttcggaact 129 <210> 2177 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2177 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 2178 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2178 cctgatcgct tctctggccc caagtctggc aacacggcct cgctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcaccta cacttacgtc 120 ttcggaact 129 <210> 2179 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2179 Pro Asp Arg Phe Ser Gly Pro Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Thr Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 2180 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2180 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Lys Val Phe 1 5 10 <210> 2181 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2181 gatcgcttct ctggctccaa gtcttgcaac acggcctccc tgaccatctc tgggctccag 60 gctgagtatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcaaggta 120 ttcggcgga 129 <210> 2182 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2182 Asp Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Tyr Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Lys Val Phe Gly Gly 35 40 <210> 2183 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2183 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcaaggta 120 ttcggcgga 129 <210> 2184 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2184 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Lys Val Phe Gly Gly 35 40 <210> 2185 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2185 gttcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcaaggta 120 ttcggcgga 129 <210> 2186 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2186 Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Lys Val Phe Gly Gly 35 40 <210> 2187 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2187 atccgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac tttcaaggta 120 ttcggcgga 129 <210> 2188 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2188 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Phe Lys Val Phe Gly Gly 35 40 <210> 2189 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2189 Cys Ser Tyr Thr Val Ser Ser Thr Tyr Leu Phe 1 5 10 <210> 2190 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2190 tctagtcgct tctcttgctc caagtctgcc gacacggcct ccctgtccat ctctgggctg 60 caggctgagg acgaggctga ttattactgc tgctcatata cagttagcag cacttatctc 120 ttcggcact 129 <210> 2191 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2191 Ser Ser Arg Phe Ser Cys Ser Lys Ser Ala Asp Thr Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Val Ser Ser Thr Tyr Leu Phe Gly Thr 35 40 <210> 2192 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2192 tctagtcgct tctctggctc caagtctgcc gacacggcct ccctgaccat ctctgggctg 60 caggctgagg acgaggctga ttattactgc tgctcatata cagttagcag cacttatctc 120 ttcggcact 129 <210> 2193 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2193 Ser Ser Arg Phe Ser Gly Ser Lys Ser Ala Asp Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Val Ser Ser Thr Tyr Leu Phe Gly Thr 35 40 <210> 2194 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2194 tctagtcgct tctctggctc caagtcagcc gacacggcct ccctgaccat ctctgggctc 60 caggctgaag acgaagctga ttattactgc tgctcatata cagttagtag cacttatctc 120 ttcggcact 129 <210> 2195 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2195 Cys Ser Phe Glu Gly Ser Ser Thr Leu Trp Val Phe 1 5 10 <210> 2196 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2196 attcgtttct ctggctccaa gtccggcaac acggcctccc tgacaatctc tgtgctccag 60 gctgaggacg gggctgatta ttactgctgc tcgtttgaag gtagcagcac tctttgggtg 120 ttcggcgga 129 <210> 2197 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2197 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Val Leu Gln Ala Glu Asp Gly Ala Asp Tyr Tyr Cys Cys Ser Phe 20 25 30 Glu Gly Ser Ser Thr Leu Trp Val Phe Gly Gly 35 40 <210> 2198 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2198 attcgtttct ctggctccaa gtccggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg tggctgatta ttactgctgc tcgtttgaag gtagcagcac tctttgggtg 120 ttcggcgga 129 <210> 2199 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2199 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Val Ala Asp Tyr Tyr Cys Cys Ser Phe 20 25 30 Glu Gly Ser Ser Thr Leu Trp Val Phe Gly Gly 35 40 <210> 2200 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2200 aatcgtttct ctggctccaa gtccggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg gggctgatta ttactgctgc tcgtttgaag gtagcagcac tctttgggtg 120 ttcggcgga 129 <210> 2201 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2201 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Gly Ala Asp Tyr Tyr Cys Cys Ser Phe 20 25 30 Glu Gly Ser Ser Thr Leu Trp Val Phe Gly Gly 35 40 <210> 2202 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2202 Cys Ser Tyr Ala Gly Ser Ser Thr Pro Phe 1 5 10 <210> 2203 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2203 tttctaatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcactccc 120 ttcggaact 129 <210> 2204 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2204 Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Pro Phe Gly Thr 35 40 <210> 2205 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2205 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac tatctctggg 60 ctcctggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcactccc 120 ttcggaact 129 <210> 2206 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2206 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Pro Phe Gly Thr 35 40 <210> 2207 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2207 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagcactccc 120 ttcggaact 129 <210> 2208 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2208 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Thr Pro Phe Gly Thr 35 40 <210> 2209 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2209 Cys Ser Tyr Ala Gly Arg Asp Val Phe 1 5 <210> 2210 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2210 ggtgtttcta atcgcttctc tgtctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagggatgtc 120 ttcggaact 129 <210> 2211 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2211 Gly Val Ser Asn Arg Phe Ser Val Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Arg Asp Val Phe Gly Thr 35 40 <210> 2212 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2212 ggtgtttcta atcgcttctc tggctccaag tctggcaaca cggcctccct gactatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagggatgtc 120 ttcggaact 129 <210> 2213 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2213 Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Arg Asp Val Phe Gly Thr 35 40 <210> 2214 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2214 ggggtttcta atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagggatgtc 120 ttcggaact 129 <210> 2215 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2215 Cys Ser Tyr Ala Gly Ser Tyr Thr Val Ile Phe 1 5 10 <210> 2216 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2216 cctgatcgct tctctggctc caagtctggc aactcggcct ccctgacgat ctctgggctc 60 caggctgagg atgaagctga ttattactgc tgctcatatg caggcagcta cactgtgata 120 ttcggcgga 129 <210> 2217 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2217 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Ile Phe Gly Gly 35 40 <210> 2218 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2218 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgtgctc 60 catgctgagg atgaagctga ttattactgc tgctcatatg caggcagcta cactgtgata 120 ttcggcgga 129 <210> 2219 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2219 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu His Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Ile Phe Gly Gly 35 40 <210> 2220 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2220 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaagctga ttattactgc tgctcatatg caggcagcta cactgtgata 120 ttcggcgga 129 <210> 2221 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2221 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Val Ile Phe Gly Gly 35 40 <210> 2222 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2222 Cys Ser Tyr Ala Gly Thr Tyr Val Val Phe 1 5 10 <210> 2223 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2223 gtttcgtatc gcttctctgg ctctaagtct ggctacacgg cctccctgac aatctcttgg 60 ctccaggctg aggacgaggc tgattattcc tgctgctcat atgcaggtac ttatgtggtc 120 ttcggcgga 129 <210> 2224 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2224 Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Ser Cys Cys 20 25 30 Ser Tyr Ala Gly Thr Tyr Val Val Phe Gly Gly 35 40 <210> 2225 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2225 gtttcgaatc gcttctctgg ctctaagtct ggctacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattcc tgctgctcat atgcaggtac ttatgtggtc 120 ttcggcgga 129 <210> 2226 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2226 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Ser Cys Cys 20 25 30 Ser Tyr Ala Gly Thr Tyr Val Val Phe Gly Gly 35 40 <210> 2227 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2227 gtttcgaatc gcttctctgg ctctaagtct ggctacacgg cctccctgac aacctctggg 60 ctccaggctg aggacgaggc tgattattcc cgctgctcat atgcaggtac ttatgtggtc 120 ttcggcgga 129 <210> 2228 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2228 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu 1 5 10 15 Thr Thr Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Ser Arg Cys 20 25 30 Ser Tyr Ala Gly Thr Tyr Val Val Phe Gly Gly 35 40 <210> 2229 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2229 Cys Ser Tyr Ala Gly Ser Ser Ser Phe Phe 1 5 10 <210> 2230 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2230 tttctaatcc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagctctttc 120 ttcggaact 129 <210> 2231 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2231 Phe Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Ser Phe Phe Gly Thr 35 40 <210> 2232 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2232 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctgctggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagctctttc 120 ttcggaact 129 <210> 2233 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2233 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Ser Phe Phe Gly Thr 35 40 <210> 2234 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2234 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagctctttc 120 ttcggaact 129 <210> 2235 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2235 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Ser Phe Phe Gly Thr 35 40 <210> 2236 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2236 Cys Ser Tyr Ala Gly Ser Ser Thr Ser Tyr Val Phe 1 5 10 <210> 2237 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2237 aatcgcttct ctggctctaa gtctggcaac acagcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttcttatgtc 120 ttcggaact 129 <210> 2238 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2238 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Tyr Val Phe Gly Thr 35 40 <210> 2239 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2239 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttcttatgtc 120 ttcggaact 129 <210> 2240 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2240 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttcttatgtc 120 ttcggaact 129 <210> 2241 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2241 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Tyr Val Phe Gly Thr 35 40 <210> 2242 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2242 Cys Ser Tyr Ala Gly Ser Ser Tyr Val Phe 1 5 10 <210> 2243 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2243 gtccctgttc gcttctctgg ctccaagtct ggcaacacgg cctccctgac catgtctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctcttatgtc 120 ttcggaact 129 <210> 2244 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2244 Val Pro Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Met Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Tyr Val Phe Gly Thr 35 40 <210> 2245 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2245 gtccctgatc gcttgtctgg ctccatgtct ggcaacacgg cctccctgac catctctggg 60 ctccagtctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctcttatgtc 120 ttcggaact 129 <210> 2246 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2246 Val Pro Asp Arg Leu Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Tyr Val Phe Gly Thr 35 40 <210> 2247 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2247 gtccctgatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atgcaggcag ctcttatgtc 120 ttcggaact 129 <210> 2248 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2248 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Tyr Val Phe Gly Thr 35 40 <210> 2249 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2249 Cys Ser Tyr Ala Gly Ser Ser Pro Val Phe 1 5 10 <210> 2250 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2250 gtttctaatc tcttctctgg ctccaagtct ggctacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagccctgta 120 ttcggcgga 129 <210> 2251 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2251 Val Ser Asn Leu Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Pro Val Phe Gly Gly 35 40 <210> 2252 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2252 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagccctgta 120 ttcggcgga 129 <210> 2253 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2253 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Pro Val Phe Gly Gly 35 40 <210> 2254 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2254 ggtttctatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattattac tgctgctcat atgcaggtag tagccctgta 120 ttcggcgga 129 <210> 2255 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2255 Gly Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Pro Val Phe Gly Gly 35 40 <210> 2256 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2256 Cys Ser Tyr Ala Gly Asn Ser Tyr Val Phe 1 5 10 <210> 2257 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2257 gtcgctgatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac catctctggg 60 ctcgaggctg acgatgaggc tgattattac tgctgctcat atgcaggcaa ctcttatgtc 120 ttcggaact 129 <210> 2258 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2258 Val Ala Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Glu Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Asn Ser Tyr Val Phe Gly Thr 35 40 <210> 2259 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2259 gtccctgatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac catctctggg 60 ctccaggctg acgatgaggc tgattattac tgctgctcat atgcaggcaa ctcttatgtc 120 ttcggaact 129 <210> 2260 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2260 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Asn Ser Tyr Val Phe Gly Thr 35 40 <210> 2261 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2261 gtacctgatc gcttctctgg ctccaagtct ggcaactcgg cctccctgac catctctggg 60 ctccaggctg acgatgaggc tgattattac tgctgctcat atgcaggcaa ctcttatgtc 120 ttcggaact 129 <210> 2262 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2262 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Asn Ser Tyr Val Phe Gly Thr 35 40 <210> 2263 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2263 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe 1 5 <210> 2264 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2264 agggtccctg atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagctacact 120 ttcggcgga 129 <210> 2265 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2265 Arg Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Gly Gly 35 40 <210> 2266 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2266 ggggtccctg atcgcttctc tggctccaag tctggcaact cggcctccct gagcatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagctacact 120 ttcggcgga 129 <210> 2267 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2267 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser 1 5 10 15 Leu Ser Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Gly Gly 35 40 <210> 2268 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2268 ggggtccctg atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cagctacact 120 ttcggcgga 129 <210> 2269 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2269 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Gly Gly 35 40 <210> 2270 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2270 Cys Ser Tyr Ala Gly Ser Tyr Ser Met Ile Phe 1 5 10 <210> 2271 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2271 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cagtatgata 120 ttcggcgga 129 <210> 2272 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2272 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Met Ile Phe Gly Gly 35 40 <210> 2273 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2273 cctaatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cagcatgata 120 ttcggcgga 129 <210> 2274 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2274 Pro Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Met Ile Phe Gly Gly 35 40 <210> 2275 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2275 ccgtttcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cagtatgata 120 ttcggcgga 129 <210> 2276 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2276 Pro Phe Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Met Ile Phe Gly Gly 35 40 <210> 2277 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2277 Cys Ser Tyr Ala Gly Ser Ser Thr Ser Val Phe 1 5 10 <210> 2278 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2278 ttctatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttccgta 120 ttcggcgga 129 <210> 2279 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2279 Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Ser Val Phe Gly Gly 35 40 <210> 2280 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2280 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttccgta 120 ttcggcgga 129 <210> 2281 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2281 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Ser Val Phe Gly Gly 35 40 <210> 2282 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2282 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacttccgta 120 ttcggcgga 129 <210> 2283 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2283 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Ser Val Phe Gly Gly 35 40 <210> 2284 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2284 Cys Ser Tyr Ala Val Thr Asn Ser Phe Leu Phe 1 5 10 <210> 2285 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2285 cctgttcgct tctctggctc caagtctggc aactcggcct ccctgaccat ctctgggctc 60 caggctgaag atgaggctga ttattactgc tgctcatatg cagtcaccaa cagttttctc 120 ttcggaact 129 <210> 2286 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2286 Pro Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Val Thr Asn Ser Phe Leu Phe Gly Thr 35 40 <210> 2287 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2287 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctcttggctc 60 cagtctgaag atgaggctga ttattactgc tgctcatatg cagtcaccaa cagttttctc 120 ttcggaact 129 <210> 2288 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2288 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Val Thr Asn Ser Phe Leu Phe Gly Thr 35 40 <210> 2289 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2289 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgaag atgaggctga ttattactgc tgctcatatg cagtcaccaa cagttttctc 120 ttcggaact 129 <210> 2290 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2290 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Val Thr Asn Ser Phe Leu Phe Gly Thr 35 40 <210> 2291 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2291 Cys Ser Tyr Ser Ser Ser Ser Thr Leu Val Val Phe 1 5 10 <210> 2292 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2292 tatcgattct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatattcaa gcagcagcac tctcgtagta 120 ttcggcgga 129 <210> 2293 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2293 Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ser Ser Ser Ser Thr Leu Val Val Phe Gly Gly 35 40 <210> 2294 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2294 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatattcaa gcagcagcac tctcgtagta 120 ttcggcgga 129 <210> 2295 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2295 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ser Ser Ser Ser Thr Leu Val Val Phe Gly Gly 35 40 <210> 2296 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2296 attcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatattcaa gcagcagcac tctcgtagta 120 ttcggcgga 129 <210> 2297 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2297 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ser Ser Ser Ser Thr Leu Val Val Phe Gly Gly 35 40 <210> 2298 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2298 tctggtcgct tgtctggctc caagtcttgc tacacggcct ccctgacaat ctctgggctc 60 caggcagagg acgaggctga ttattactgc tgctcatatg caggcagtag cactttgttg 120 ttcggcgga 129 <210> 2299 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2299 Ser Gly Arg Leu Ser Gly Ser Lys Ser Cys Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Leu Phe Gly Gly 35 40 <210> 2300 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2300 tctggtcgct tgtctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggcagagg acgaggctga ttattactgc tgctcatatg caggcagtag cactttgttg 120 ttcggcgga 129 <210> 2301 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2301 Ser Gly Arg Leu Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Leu Phe Gly Gly 35 40 <210> 2302 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2302 tctggtcgct tgtctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggcagagg acgaggctga ttattactgc tgctcatatg caggcagcag cactttgttg 120 ttcggccga 129 <210> 2303 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2303 Ser Gly Arg Leu Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Leu Leu Phe Gly Arg 35 40 <210> 2304 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2304 Cys Ser Tyr Gly Asp Thr Ser Pro Val Ile Phe 1 5 10 <210> 2305 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2305 tctgatcgct tctctgtctc caagtctggc aatacggcct cccttgcaat ctcttggctc 60 cagactgagg acgaggctga ttatttctgc tgctcatatg gagatactag ccccgtgata 120 ttcggcgga 129 <210> 2306 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2306 Ser Asp Arg Phe Ser Val Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala 1 5 10 15 Ile Ser Trp Leu Gln Thr Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Gly Asp Thr Ser Pro Val Ile Phe Gly Gly 35 40 <210> 2307 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2307 tctgatcgct tctctggctc caagtctggc aatacggcct ccctggcaat ctctgggctc 60 cagactgagg acgaggctga ttatttctgc tgctcatatg gagatactag ccccgtgata 120 ttcggcgga 129 <210> 2308 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2308 Ser Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala 1 5 10 15 Ile Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Gly Asp Thr Ser Pro Val Ile Phe Gly Gly 35 40 <210> 2309 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2309 ctgatccgct tctctggctc caagtctggc aatacggcct ccctggcaat ctctgggctc 60 cagactgagg acgaggctga ttatttctgc tgctcatatg gagatactag ccccgtgata 120 ttcggcgga 129 <210> 2310 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2310 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala 1 5 10 15 Ile Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Gly Asp Thr Ser Pro Val Ile Phe Gly Gly 35 40 <210> 2311 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2311 Cys Ser Tyr Ala Thr Gly Phe Tyr Val Phe 1 5 10 <210> 2312 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2312 ttttctaatc gcttctctgg ctccaagtct gacaacacgg cctccctgac aatctctggg 60 ctccagactg aggacgaggc tgactatcac tgctgctcat atgcaactgg tttttatgtc 120 ttcggagct 129 <210> 2313 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2313 Phe Ser Asn Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr His Cys Cys 20 25 30 Ser Tyr Ala Thr Gly Phe Tyr Val Phe Gly Ala 35 40 <210> 2314 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2314 atttctaatc gcttctctgg ctccaagtct gacaacacgg cctccctgac aatctctggg 60 ctccagactg aggacgaggc tgactatcac tgctgctcat atgcaactgg tttttatgtc 120 ttcggagct 129 <210> 2315 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2315 Ile Ser Asn Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr His Cys Cys 20 25 30 Ser Tyr Ala Thr Gly Phe Tyr Val Phe Gly Ala 35 40 <210> 2316 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2316 atatctactc gcttctctgg ctccaagtct gacaacacgg cctccctgac aatctctggg 60 ctccagactg aggacgaggc tgactatcac tgctgctcat atgcaactgg tttttatgtc 120 ttcggagct 129 <210> 2317 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2317 Ile Ser Thr Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr His Cys Cys 20 25 30 Ser Tyr Ala Thr Gly Phe Tyr Val Phe Gly Ala 35 40 <210> 2318 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2318 Cys Ser Tyr Ala Gly Ser Ser Ser Tyr Val Val Phe 1 5 10 <210> 2319 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2319 tatcgcttct ctggctccaa gtctggcaac acggcctccc tgactatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagctc atatgtggta 120 ttcggcgga 129 <210> 2320 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2320 Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Ser Tyr Val Val Phe Gly Gly 35 40 <210> 2321 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2321 aatcgcttct ctggctccat gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagctc ttatgtggta 120 ttcggcgga 129 <210> 2322 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2322 Asn Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Ser Tyr Val Val Phe Gly Gly 35 40 <210> 2323 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2323 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgtcaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagctc ttatgtggta 120 ttcggcgga 129 <210> 2324 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2324 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Ser Tyr Val Val Phe Gly Gly 35 40 <210> 2325 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2325 Cys Ser Tyr Ala Gly Asn Leu Trp Leu Phe 1 5 10 <210> 2326 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2326 gtccctgatc gcttctctgg ctcgaagtct ggcaacacgg cctccctgac catctcttgg 60 ctccaggctg aggatgaggc tgattattac tgttgctcat atgcaggcaa cctctggctg 120 ttcggcgga 129 <210> 2327 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2327 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Asn Leu Trp Leu Phe Gly Gly 35 40 <210> 2328 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2328 gtccctgatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgttgctcat atgcaggcaa cctctggctg 120 ttcggcgga 129 <210> 2329 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2329 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Asn Leu Trp Leu Phe Gly Gly 35 40 <210> 2330 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2330 ggccctgatc gcttctctgg ctccaaggct ggcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgttgctcat atgcaggcaa cctctggctg 120 ttcggcgga 129 <210> 2331 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2331 Gly Pro Asp Arg Phe Ser Gly Ser Lys Ala Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Asn Leu Trp Leu Phe Gly Gly 35 40 <210> 2332 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2332 Cys Ser Tyr Ala Gly Thr Val Val Phe 1 5 <210> 2333 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2333 ggtgtccctg atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 tggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cactgtggta 120 ttcggcgga 129 <210> 2334 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2334 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Thr Val Val Phe Gly Gly 35 40 <210> 2335 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2335 ggggtccctg atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cactgtggta 120 ttcggcgga 129 <210> 2336 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2336 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Thr Val Val Phe Gly Gly 35 40 <210> 2337 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2337 ggggtcccta atcgcttctc tggctccaag tctggcgaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg cactgtggta 120 ttcggcgga 129 <210> 2338 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2338 Gly Val Pro Asn Arg Phe Ser Gly Ser Lys Ser Gly Asp Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Thr Val Val Phe Gly Gly 35 40 <210> 2339 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2339 Cys Ser Tyr Ala Gly Ser Ser Ser Trp Val Phe 1 5 10 <210> 2340 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2340 tctaatcgct tctctggctc caagtctggt agcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttgggtg 120 ttcggcgga 129 <210> 2341 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2341 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ser Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Trp Val Phe Gly Gly 35 40 <210> 2342 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2342 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttgggtg 120 ttcggcgga 129 <210> 2343 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2343 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Trp Val Phe Gly Gly 35 40 <210> 2344 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2344 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttgggtg 120 ttcggcgga 129 <210> 2345 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2345 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Trp Val Phe Gly Gly 35 40 <210> 2346 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2346 Cys Ser Tyr Ala Gly Ser Ser Asn Trp Val Phe 1 5 10 <210> 2347 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2347 tctattcgct tctctggctc caagtctggc tacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag caattgggtg 120 ttcggcgga 129 <210> 2348 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2348 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Asn Trp Val Phe Gly Gly 35 40 <210> 2349 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2349 tctattcgct tctctggctc caagtctggc aacacggcct cgctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag caattgggtg 120 ttcggcgga 129 <210> 2350 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2350 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Asn Trp Val Phe Gly Gly 35 40 <210> 2351 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2351 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag caattgggtg 120 ttcggcgga 129 <210> 2352 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2352 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Asn Trp Val Phe Gly Gly 35 40 <210> 2353 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2353 Cys Ser Tyr Ala Gly Ser Ser Pro Val Val Phe 1 5 10 <210> 2354 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2354 ttctatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ccctgtggta 120 ttcggcgga 129 <210> 2355 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2355 Phe Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Pro Val Val Phe Gly Gly 35 40 <210> 2356 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2356 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ccctgtggta 120 ttcggcgga 129 <210> 2357 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2357 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Pro Val Val Phe Gly Gly 35 40 <210> 2358 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2358 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ccctgtggta 120 ttcggcgga 129 <210> 2359 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2359 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Pro Val Val Phe Gly Gly 35 40 <210> 2360 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2360 Cys Ser Tyr Thr Gly Thr Tyr Val Ile Phe 1 5 10 <210> 2361 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2361 gtccctgatc gcttctctgg ctccaagtct gtcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat ataccggcac ctatgtgata 120 ttccgcgga 129 <210> 2362 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2362 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Thr Gly Thr Tyr Val Ile Phe Arg Gly 35 40 <210> 2363 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2363 gtccctgatc gcttctctgg ctccaagtct gtcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atacaggcac ctatgtgata 120 ttcggcgga 129 <210> 2364 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2364 Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Thr Gly Thr Tyr Val Ile Phe Gly Gly 35 40 <210> 2365 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2365 ggtcctgatc gcttctctgg ctccaagtct gtcaacacgg cctccctgac catctctggg 60 ctccaggctg aggatgaggc tgattattac tgctgctcat atacaggcac ctatgtgata 120 ttcggcgga 129 <210> 2366 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2366 Gly Pro Asp Arg Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Thr Gly Thr Tyr Val Ile Phe Gly Gly 35 40 <210> 2367 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2367 cctgatcgct tctctggctc caagtctggc atcacggcct ccctgaccat ctctgggctc 60 caggctgagg atgagtctga ttattactgc tgctcatatg caggcagcta cacttttgtc 120 ttcggaact 129 <210> 2368 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2368 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Phe Val Phe Gly Thr 35 40 <210> 2369 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2369 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 cgggctgaag atgaggctga ttattactgc tgctcatatg caggcagcta cacttttgtc 120 ttcggaact 129 <210> 2370 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2370 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Arg Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Phe Val Phe Gly Thr 35 40 <210> 2371 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2371 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cacttttgtc 120 ttcggaact 129 <210> 2372 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2372 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Phe Val Phe Gly Thr 35 40 <210> 2373 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2373 Cys Ser Tyr Ala Gly Ser Thr Thr Leu Leu Phe 1 5 10 <210> 2374 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2374 tctaatcgct tctctggctc caagtctggc agctcggcct ccctgacatt ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtac cactttactg 120 ttcggcgga 129 <210> 2375 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2375 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ser Ser Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Thr Thr Leu Leu Phe Gly Gly 35 40 <210> 2376 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2376 tctaatcgct tctctggctc caagtctggc agcacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtac cactttactg 120 ttcggcgga 129 <210> 2377 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2377 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ser Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Thr Thr Leu Leu Phe Gly Gly 35 40 <210> 2378 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2378 tctaatcgct tctctggctc caagtctggc agcacggcct ccctgacaat ctctgggatc 60 caggccgagg acgaggctga ttattactgc tgctcatatg caggtagtac cactttactg 120 ttcggcgga 129 <210> 2379 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2379 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ser Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Ile Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Thr Thr Leu Leu Phe Gly Gly 35 40 <210> 2380 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2380 Cys Ser Tyr Ala Gly Ser Thr Thr Leu Val Phe 1 5 10 <210> 2381 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2381 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtac cactttggta 120 ttcggcggc 129 <210> 2382 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2382 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Thr Thr Leu Val Phe Gly Gly 35 40 <210> 2383 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2383 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtac cactttggta 120 ttcggcgga 129 <210> 2384 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2384 cctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgggg acgaggctga ttattactgc tgctcatatg caggtagtac cactttggta 120 ttcggcgga 129 <210> 2385 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2385 Pro Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Gly Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Thr Thr Leu Val Phe Gly Gly 35 40 <210> 2386 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2386 Cys Ser Tyr Ala Gly Ser Tyr Ser Val Val Phe 1 5 10 <210> 2387 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2387 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctccgtggtg 120 ttcggcgga 129 <210> 2388 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2388 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Val Val Phe Gly Gly 35 40 <210> 2389 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2389 cctgatcgct tctctggctc gaagtctggc aactcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctccgtggtg 120 ttcggcgga 129 <210> 2390 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2390 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Val Val Phe Gly Gly 35 40 <210> 2391 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2391 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ctccgtggtg 120 ttcggcgga 129 <210> 2392 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2392 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Val Val Phe Gly Gly 35 40 <210> 2393 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2393 Cys Ser Tyr Ala Gly Ser Tyr Phe Trp Val Phe 1 5 10 <210> 2394 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2394 cctgatcgct tctctggctc caagtctggc gacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattattgc tgctcatatg caggcagcta cttctgggtg 120 ttcggcgga 129 <210> 2395 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2395 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asp Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Phe Trp Val Phe Gly Gly 35 40 <210> 2396 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2396 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cttctgggtg 120 ttcggcgga 129 <210> 2397 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2397 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Phe Trp Val Phe Gly Gly 35 40 <210> 2398 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2398 cctgatcgct tctctggctc caaggctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atggggctga ttattactgc tgctcatatg caggcagcta cttctgggtg 120 ttcggcgga 129 <210> 2399 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2399 Pro Asp Arg Phe Ser Gly Ser Lys Ala Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Gly Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Phe Trp Val Phe Gly Gly 35 40 <210> 2400 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2400 Cys Ser Tyr Ala Gly Ser Gly Ser Tyr Val Phe 1 5 10 <210> 2401 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2401 tctgttcgct tctctgcctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga tttttactgt tgctcatatg caggtagtgg ctcttatgtc 120 ttcggaact 129 <210> 2402 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2402 Ser Val Arg Phe Ser Ala Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Phe Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Gly Ser Tyr Val Phe Gly Thr 35 40 <210> 2403 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2403 tctgatcgct tctctgcctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgt tgctcatatg caggtagtgg ctcttatgtc 120 ttcggaact 129 <210> 2404 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2404 Ser Asp Arg Phe Ser Ala Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Gly Ser Tyr Val Phe Gly Thr 35 40 <210> 2405 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2405 tctgatcgct tctctgcctc caagtctggc aacacggcct ccctgacaat ctccgggctc 60 caggctgagg acgaggctga ttattactgt tgctcatatg caggtagtgg ctcttatgtc 120 ttcggaact 129 <210> 2406 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2406 Cys Ser Tyr Ala Gly Ser Tyr Pro Val Val Phe 1 5 10 <210> 2407 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2407 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ccccgtggta 120 ttcggcgga 129 <210> 2408 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2408 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Pro Val Val Phe Gly Gly 35 40 <210> 2409 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2409 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctcttggctc 60 cagtctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ccccgtggta 120 ttcggcgga 129 <210> 2410 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2410 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Pro Val Val Phe Gly Gly 35 40 <210> 2411 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2411 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta ccccgtggta 120 ttcggcgga 129 <210> 2412 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2412 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Pro Val Val Phe Gly Gly 35 40 <210> 2413 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2413 Cys Ser Tyr Ala Gly Ser Ser Thr Asp Val Val Phe 1 5 10 <210> 2414 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2414 actcgcttct ctggctccaa gtctggcaac acggcctccc tgactatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ggatgtggta 120 ttcggcgga 129 <210> 2415 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2415 Thr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Asp Val Val Phe Gly Gly 35 40 <210> 2416 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2416 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ggatgtggta 120 ttcggcgga 129 <210> 2417 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2417 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Asp Val Val Phe Gly Gly 35 40 <210> 2418 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2418 atacgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ggatgtggta 120 ttcggcgga 129 <210> 2419 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2419 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Asp Val Val Phe Gly Gly 35 40 <210> 2420 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2420 Cys Ser Tyr Ala Gly Ser Arg Gly Pro Tyr Val Phe 1 5 10 <210> 2421 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2421 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagagg gccttatgtc 120 ttcggaact 129 <210> 2422 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2422 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Arg Gly Pro Tyr Val Phe Gly Thr 35 40 <210> 2423 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2423 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagagg gccttatgtc 120 ttcggaact 129 <210> 2424 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2424 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Arg Gly Pro Tyr Val Phe Gly Thr 35 40 <210> 2425 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2425 Cys Ser Tyr Ala Gly Ser Arg Thr Tyr Val Phe 1 5 10 <210> 2426 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2426 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctggcctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtcg cacttatgtc 120 ttcggaact 129 <210> 2427 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2427 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Thr Tyr Val Phe Gly Thr 35 40 <210> 2428 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2428 actgatcgct tctctggctc caagtctggc aacgcggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttatttttgt tgctcatatg caggtagtag aacttatgtc 120 ttcggaact 129 <210> 2429 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2429 Thr Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ala Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Thr Tyr Val Phe Gly Thr 35 40 <210> 2430 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2430 Cys Ser Tyr Ala Gly Ser Ser Ser Cys Val Phe 1 5 10 <210> 2431 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2431 tctaatcgct tctctggctc gaagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttgtgtg 120 ttcggcgga 129 <210> 2432 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2432 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Cys Val Phe Gly Gly 35 40 <210> 2433 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2433 tctaatcgct tctctggctc catgtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag ctcttgtgtg 120 ttcggcgga 129 <210> 2434 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2434 Ser Asn Arg Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Ser Cys Val Phe Gly Gly 35 40 <210> 2435 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2435 Cys Ser Tyr Ala Gly Ser Tyr Thr Asn Val Phe 1 5 10 <210> 2436 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2436 ctgatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactaacgtc 120 ttcggaact 129 <210> 2437 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2437 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Asn Val Phe Gly Thr 35 40 <210> 2438 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2438 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcta cactaacgtc 120 ttcggaact 129 <210> 2439 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2439 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Thr Asn Val Phe Gly Thr 35 40 <210> 2440 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2440 Cys Ser Tyr Ala Ser Asp Asn Ser His Val Val Ile 1 5 10 <210> 2441 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2441 tatcggttct ctgcctccaa gtctggcaac gcggcctccc tgacaatctc tgggctccag 60 actgaggacg aggctgatta tttctgctgc tcatatgcaa gtgataactc ccatgtggtg 120 atcggcgga 129 <210> 2442 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2442 Tyr Arg Phe Ser Ala Ser Lys Ser Gly Asn Ala Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser Tyr 20 25 30 Ala Ser Asp Asn Ser His Val Val Ile Gly Gly 35 40 <210> 2443 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2443 aatcggttct ctgcctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 actgaggacg aggctgatta tttctgctgc tcatatgcaa gtgataactc ccatgtggtg 120 atcggcgga 129 <210> 2444 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2444 Asn Arg Phe Ser Ala Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser Tyr 20 25 30 Ala Ser Asp Asn Ser His Val Val Ile Gly Gly 35 40 <210> 2445 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2445 Cys Ser Tyr Ala Gly Tyr Tyr Thr Tyr Val Phe 1 5 10 <210> 2446 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2446 ctgatccgct tctccggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggctacta cacttatgtc 120 ttcggaact 129 <210> 2447 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2447 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Tyr Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 2448 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2448 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggctacta cacttatgtc 120 ttcggaact 129 <210> 2449 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2449 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Tyr Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 2450 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2450 Cys Ser Tyr Ala Gly Ser Leu Thr Tyr Val Val Phe 1 5 10 <210> 2451 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2451 aatcgcttct ctggctcctt gtctggcaac acggccaccc tgacaatctc tgggctccag 60 gctgaggacg agggtcatta ttactgctgc tcatatgcag gtagtctcac ttatgtggtc 120 ttcggcgga 129 <210> 2452 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2452 Asn Arg Phe Ser Gly Ser Leu Ser Gly Asn Thr Ala Thr Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Gly His Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Leu Thr Tyr Val Val Phe Gly Gly 35 40 <210> 2453 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2453 aatcgcttct ctggctccaa gtctggcaac acggccaccc tgacaatctc tgggctccag 60 gctgaggacg agggtcatta ttactgctgc tcatatgcag gtagtctcac ttatgtggtc 120 ttcggcgga 129 <210> 2454 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2454 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Thr Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Gly His Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Leu Thr Tyr Val Val Phe Gly Gly 35 40 <210> 2455 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2455 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Glu Phe 1 5 10 <210> 2456 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2456 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgaa 120 ttcggcgga 129 <210> 2457 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2457 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Phe Glu Phe Gly Gly 35 40 <210> 2458 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2458 tctaatcgct tctctggatc caagtctggc aacactgcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cactttcgaa 120 ttcggcgga 129 <210> 2459 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2459 Cys Ser Tyr Ala Gly Ser Tyr Ser Leu Val Val Phe 1 5 10 <210> 2460 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2460 gatcgcttct ctggctccaa gtctggcaag acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctactc tcttgtggta 120 ttcggcgga 129 <210> 2461 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2461 Asp Arg Phe Ser Gly Ser Lys Ser Gly Lys Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ser Leu Val Val Phe Gly Gly 35 40 <210> 2462 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2462 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgtccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctactc tcttgtggta 120 ttcggcgga 129 <210> 2463 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2463 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ser Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Ser Leu Val Val Phe Gly Gly 35 40 <210> 2464 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2464 Cys Ser Tyr Thr Ser Ser Asp Asn Tyr Val Phe 1 5 10 <210> 2465 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2465 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatata caagtagtga caattatgtc 120 ttcggaact 129 <210> 2466 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2466 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Ser Ser Asp Asn Tyr Val Phe Gly Thr 35 40 <210> 2467 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2467 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatata caagtagtga caattatgtc 120 ttcggaact 129 <210> 2468 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2468 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Ser Ser Asp Asn Tyr Val Phe Gly Thr 35 40 <210> 2469 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2469 Cys Ser Tyr Ala Gly Ser His Thr Tyr Val Phe 1 5 10 <210> 2470 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2470 cctgatcgct tctctggctc caagtctggc aactcggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcca cacttatgtc 120 ttcggaact 129 <210> 2471 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2471 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Thr Tyr Val Phe Gly Thr 35 40 <210> 2472 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2472 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttatttctgc tgctcatatg cagggagcca cacttatgtc 120 ttcggaact 129 <210> 2473 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2473 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Thr Tyr Val Phe Gly Thr 35 40 <210> 2474 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2474 Cys Ser Tyr Ala Gly Ser Ser Thr His Tyr Val Phe 1 5 10 <210> 2475 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2475 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tcattatgtc 120 ttcggaact 129 <210> 2476 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2476 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr His Tyr Val Phe Gly Thr 35 40 <210> 2477 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2477 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tcactacgtc 120 ttcggaact 129 <210> 2478 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2478 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Phe Val Phe 1 5 10 <210> 2479 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2479 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 actgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttttttgtc 120 ttcggaact 129 <210> 2480 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2480 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Phe Val Phe Gly Thr 35 40 <210> 2481 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2481 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 actgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttttttgtc 120 ttcggaact 129 <210> 2482 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2482 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Phe Val Phe Gly Thr 35 40 <210> 2483 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2483 Cys Ser Tyr Ala Gly Asn Tyr Val Phe 1 5 <210> 2484 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2484 ggggtccctg atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg caactatgtc 120 ttcggaact 129 <210> 2485 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2485 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Asn Tyr Val Phe Gly Thr 35 40 <210> 2486 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2486 gggggacctg atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgaggatga ggctgattat tactgctgct catatgcagg caactatgtc 120 ttcggaact 129 <210> 2487 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2487 Gly Gly Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Asn Tyr Val Phe Gly Thr 35 40 <210> 2488 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2488 Cys Ser Tyr Ala Gly Ser Arg Thr Val Val Phe 1 5 10 <210> 2489 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2489 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtcg cactgtggta 120 ttccgcgga 129 <210> 2490 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2490 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Thr Val Val Phe Arg Gly 35 40 <210> 2491 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2491 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag gactgtggta 120 ttcggcgga 129 <210> 2492 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2492 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Arg Thr Val Val Phe Gly Gly 35 40 <210> 2493 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2493 Cys Ser Tyr Ala Gly Arg Ser Thr Trp Val Leu 1 5 10 <210> 2494 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2494 tcttatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgtgctc 60 caggctgagg acgagagtga ttattactgc tgctcatatg cagggagaag cacttgggtg 120 ctcggcgga 129 <210> 2495 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2495 Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Val Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Arg Ser Thr Trp Val Leu Gly Gly 35 40 <210> 2496 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2496 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgagagtga ttattactgc tgctcatatg cagggagaag cacttgggtg 120 ctcggcgga 129 <210> 2497 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2497 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ser Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Arg Ser Thr Trp Val Leu Gly Gly 35 40 <210> 2498 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2498 Cys Ser Tyr Leu Gly Ser Gly Thr Phe Asp Val Leu Phe 1 5 10 <210> 2499 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2499 cgcttctctg gctccaagtc tggctacacg gcctccctga caatctctgt gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatttaggta gtggcacttt cgatgtgcta 120 ttcggcgga 129 <210> 2500 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2500 Arg Phe Ser Gly Ser Lys Ser Gly Tyr Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Val Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Leu 20 25 30 Gly Ser Gly Thr Phe Asp Val Leu Phe Gly Gly 35 40 <210> 2501 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2501 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatttaggta gtggcacttt cgatgtgcta 120 ttcggcgga 129 <210> 2502 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2502 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Leu 20 25 30 Gly Ser Gly Thr Phe Asp Val Leu Phe Gly Gly 35 40 <210> 2503 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2503 Cys Ser Leu Thr Ser Ser Ile Thr Leu Val Phe 1 5 10 <210> 2504 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2504 tctaatcgct tctctggctc caagtctggc aacacggcct tcctgaccat ctctgggctc 60 caggctgagg acgaggctga ttatcactgc tgctcactta caagcagcat cactctggtt 120 ttcggcgga 129 <210> 2505 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2505 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Phe Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr His Cys Cys Ser 20 25 30 Leu Thr Ser Ser Ile Thr Leu Val Phe Gly Gly 35 40 <210> 2506 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2506 ctaatccgct tctctggctc caagtctggc aacacggcct tcctgaccat ctctgggctc 60 caggctgagg acgaggctga ttatcactgc tgctcactta caagcagcat cactctggtt 120 ttcggcgga 129 <210> 2507 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2507 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Phe Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr His Cys Cys Ser 20 25 30 Leu Thr Ser Ser Ile Thr Leu Val Phe Gly Gly 35 40 <210> 2508 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2508 Cys Ser Tyr Ala Gly Ser Ser Ser Leu Gly Val Phe 1 5 10 <210> 2509 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2509 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagctc cctgggggtg 120 ttcggcgga 129 <210> 2510 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2510 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Ser Leu Gly Val Phe Gly Gly 35 40 <210> 2511 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2511 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagctc cctgggggtg 120 ttcggcgga 129 <210> 2512 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2512 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Ser Leu Gly Val Phe Gly Gly 35 40 <210> 2513 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2513 Cys Ser Tyr Ala Gly Asn Tyr Thr Tyr Val Phe 1 5 10 <210> 2514 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2514 ccggttcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattgctgc tgctcatatg caggcaacta cacttatgtc 120 ttcggatct 129 <210> 2515 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2515 Pro Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Cys Cys Cys Ser 20 25 30 Tyr Ala Gly Asn Tyr Thr Tyr Val Phe Gly Ser 35 40 <210> 2516 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2516 ccggatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattgctgc tgctcatatg caggcaacta cacttatgtc 120 ttcggaact 129 <210> 2517 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2517 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Cys Cys Cys Ser 20 25 30 Tyr Ala Gly Asn Tyr Thr Tyr Val Phe Gly Thr 35 40 <210> 2518 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2518 Cys Ser Tyr Ala Gly Ser His Ala Tyr Val Phe 1 5 10 <210> 2519 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2519 cctgatcgct tctctgtctc caagtctggc atcacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcca cgcttatgtc 120 ttcggaacc 129 <210> 2520 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2520 Pro Asp Arg Phe Ser Val Ser Lys Ser Gly Ile Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Ala Tyr Val Phe Gly Thr 35 40 <210> 2521 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2521 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcca cgcttatgtc 120 ttcggaacc 129 <210> 2522 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2522 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Ala Tyr Val Phe Gly Thr 35 40 <210> 2523 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2523 Cys Ser Tyr Ala Gly Ser Ser Thr Leu Trp Val Phe 1 5 10 <210> 2524 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2524 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tctttgggtg 120 ttcggcgga 129 <210> 2525 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2525 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Leu Trp Val Phe Gly Gly 35 40 <210> 2526 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2526 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tctttgggtg 120 ttcggcgga 129 <210> 2527 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2527 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Leu Trp Val Phe Gly Gly 35 40 <210> 2528 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2528 gtttctaatc gcttctctgg ctccaagtct ggcatcaggg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattatcac tgctgctcat atgcaggtag tagcggggta 120 ttcggcgga 129 <210> 2529 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2529 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Ile Arg Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr His Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Gly Val Phe Gly Gly 35 40 <210> 2530 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2530 gtttctaatc gcttctctgg ctccaagtct ggcaacacgg cctccctgac aatctctggg 60 ctccaggctg aggacgaggc tgattatcac tgctgctcat atgcaggtag tagcggggta 120 ttcggcgga 129 <210> 2531 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2531 Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr His Cys Cys 20 25 30 Ser Tyr Ala Gly Ser Ser Gly Val Phe Gly Gly 35 40 <210> 2532 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2532 Cys Ser Phe Ala Gly Ala Tyr Leu Phe 1 5 <210> 2533 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2533 ggggtccctg atcgcttctc cggctccaag tctggcatca cggcctccct gaccatctct 60 gtgctccagg ctgacgatga ggctgattat tattgctgct catttgcagg cgcctactta 120 ttcggcgga 129 <210> 2534 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2534 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Val Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Phe Ala Gly Ala Tyr Leu Phe Gly Gly 35 40 <210> 2535 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2535 ggggtccctg atcgcttctc cggctccaag tctggcaaca cggcctccct gaccatctct 60 gggctccagg ctgacgatga ggctgattat tattgctgct catttgcagg cgcctactta 120 ttcggcgga 129 <210> 2536 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2536 Gly Val Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Phe Ala Gly Ala Tyr Leu Phe Gly Gly 35 40 <210> 2537 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2537 Cys Ser Tyr Ala Gly Asp Tyr Thr Leu Leu Phe 1 5 10 <210> 2538 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2538 tctaatcgct tctctgtctt caagtctgac aacactgcct ccctgacaat ctctgggctc 60 caggctgagg acgagggtga ttattattgc tgctcatatg caggtgatta cactttgtta 120 ttcggcgga 129 <210> 2539 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2539 Ser Asn Arg Phe Ser Val Phe Lys Ser Asp Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Gly Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Asp Tyr Thr Leu Leu Phe Gly Gly 35 40 <210> 2540 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2540 tctaatcgct tctctggctt caagtctgac aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgagggtga ttattattgc tgctcatatg caggtgatta cactttgtta 120 ttcggcgga 129 <210> 2541 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2541 Ser Asn Arg Phe Ser Gly Phe Lys Ser Asp Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Gly Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Asp Tyr Thr Leu Leu Phe Gly Gly 35 40 <210> 2542 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2542 Cys Ser Tyr Thr Ser Ser Gly Thr Leu Val Val Phe 1 5 10 <210> 2543 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2543 aatcgcttct ctggctccaa gtctggcaac acggcctccc tggccatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatacaa gcagtggcac tcttgtggtt 120 ttcggcgga 129 <210> 2544 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2544 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Thr Ser Ser Gly Thr Leu Val Val Phe Gly Gly 35 40 <210> 2545 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2545 atccgcttct ctggctccaa gtctggcaac acggcctccc tggccatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatacaa gcagtggcac tcttgtggtt 120 ttcggcgga 129 <210> 2546 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2546 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Thr Ser Ser Gly Thr Leu Val Val Phe Gly Gly 35 40 <210> 2547 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2547 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Lys Ala Tyr Val Phe 1 5 10 <210> 2548 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2548 ttctctggct ccatgtctgg caacacggcc tccctgacta tctctgggct ccaggctgag 60 gacgaggctg attattactg ctgctcatat gcaggtagta gcactttcaa ggcttatgtc 120 ttcggaact 129 <210> 2549 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2549 Phe Ser Gly Ser Met Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser Gly 1 5 10 15 Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala Gly 20 25 30 Ser Ser Thr Phe Lys Ala Tyr Val Phe Gly Thr 35 40 <210> 2550 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2550 ttctctggct ccaagtctgg caacacggcc tccctgacaa tctctgggct ccaggctgag 60 gacgaggctg attattactg ctgctcatat gcaggtagta gcactttcaa ggcttatgtc 120 ttcggaact 129 <210> 2551 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2551 Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser Gly 1 5 10 15 Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala Gly 20 25 30 Ser Ser Thr Phe Lys Ala Tyr Val Phe Gly Thr 35 40 <210> 2552 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2552 Cys Ser Tyr Ala Gly Ser His Thr Val Val Phe 1 5 10 <210> 2553 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2553 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg ccggcagcca cactgtggta 120 ttcggcgga 129 <210> 2554 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2554 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Thr Val Val Phe Gly Gly 35 40 <210> 2555 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2555 cctgatcgct tctctggctc caagcctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagcca cactgtggta 120 ttcggcgga 129 <210> 2556 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2556 Pro Asp Arg Phe Ser Gly Ser Lys Pro Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser His Thr Val Val Phe Gly Gly 35 40 <210> 2557 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2557 Cys Ser Tyr Ala Gly Ser Phe Thr Leu Val Phe 1 5 10 <210> 2558 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2558 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgacgat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagctt cactttggta 120 ttcggcgga 129 <210> 2559 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2559 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Phe Thr Leu Val Phe Gly Gly 35 40 <210> 2560 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2560 cctgatcgct tctctggctc caagtctgac aacacggcct ccctgagcat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatatg caggcagctt cactttggta 120 ttcggcgga 129 <210> 2561 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2561 Pro Asp Arg Phe Ser Gly Ser Lys Ser Asp Asn Thr Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Phe Thr Leu Val Phe Gly Gly 35 40 <210> 2562 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2562 Cys Ser Tyr Val Gly Ser Asp Ile Trp Val Phe 1 5 10 <210> 2563 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2563 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctggcctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg taggtagtga catttgggtg 120 ttcggcgga 129 <210> 2564 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2564 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Val Gly Ser Asp Ile Trp Val Phe Gly Gly 35 40 <210> 2565 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2565 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctggcctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg taggtagtga catttgggtg 120 ttcggcgga 129 <210> 2566 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2566 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Val Gly Ser Asp Ile Trp Val Phe Gly Gly 35 40 <210> 2567 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2567 Cys Ser Tyr Ala Gly Ser Ser Thr Leu Asn Val Phe 1 5 10 <210> 2568 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2568 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttaaatgtc 120 ttcggaact 129 <210> 2569 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2569 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Leu Asn Val Phe Gly Thr 35 40 <210> 2570 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2570 aatcgcttct ctggctccaa gtctggcaac acggcccccc tgacaatctc ttggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttaaatgtc 120 ttcggaact 129 <210> 2571 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2571 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Pro Leu Thr Ile 1 5 10 15 Ser Trp Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Leu Asn Val Phe Gly Thr 35 40 <210> 2572 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2572 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Ala Tyr Val Val Phe 1 5 10 <210> 2573 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2573 ttctctggct ccaagtctgt caacacggcc tccctgacaa tctctgggct ccagtctgag 60 gacgaggctg attattactg ctgctcatat gcaggtagta gcactttcgc ctatgtggta 120 ttcggcgga 129 <210> 2574 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2574 Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu Thr Ile Ser Gly 1 5 10 15 Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala Gly 20 25 30 Ser Ser Thr Phe Ala Tyr Val Val Phe Gly Gly 35 40 <210> 2575 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2575 ttctctggct ccaagtctgg caacacggcc tccctgacaa tctctgggct ccaggctgag 60 gacgaggctg attattactg ctgctcatat gcaggtagta gcactttcgc ctatgtggta 120 ttcggcgga 129 <210> 2576 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2576 Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser Gly 1 5 10 15 Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala Gly 20 25 30 Ser Ser Thr Phe Ala Tyr Val Val Phe Gly Gly 35 40 <210> 2577 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2577 Cys Ser Phe Glu Gly Thr Asp Asn Gly Tyr Val Phe 1 5 10 <210> 2578 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2578 gatcgcttct ctggctccaa gtctggcatc acggcctccc tgtccgtctc tgggctcctg 60 gctgaggatg aggctgatta ttactgctgc tcatttgaag gcaccgacaa tggttatgtc 120 ttcggagct 129 <210> 2579 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2579 Asp Arg Phe Ser Gly Ser Lys Ser Gly Ile Thr Ala Ser Leu Ser Val 1 5 10 15 Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Phe 20 25 30 Glu Gly Thr Asp Asn Gly Tyr Val Phe Gly Ala 35 40 <210> 2580 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2580 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccgtctc tgggctcctg 60 gctgaggatg aggctgatta ttactgctgc tcatttgaag gcaccgacaa tggttatgtc 120 ttcggagct 129 <210> 2581 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2581 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Val 1 5 10 15 Ser Gly Leu Leu Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Phe 20 25 30 Glu Gly Thr Asp Asn Gly Tyr Val Phe Gly Ala 35 40 <210> 2582 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2582 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Val Leu Phe 1 5 10 <210> 2583 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2583 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtgcta 120 ttccgcgga 129 <210> 2584 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2584 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Leu Phe Arg Gly 35 40 <210> 2585 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2585 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac tttcgtccta 120 ttcggcgga 129 <210> 2586 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2586 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Phe Val Leu Phe Gly Gly 35 40 <210> 2587 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2587 Cys Ser Phe Val Arg Ser Ser Ala His Val Val Phe 1 5 10 <210> 2588 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2588 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatttgtac gtagtagcgc tcatgtggtc 120 ttcggcgga 129 <210> 2589 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2589 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Phe 20 25 30 Val Arg Ser Ser Ala His Val Val Phe Gly Gly 35 40 <210> 2590 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2590 tatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatttgtac gtagtagcgc tcatgtggtc 120 ttcggcgga 129 <210> 2591 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2591 Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Phe 20 25 30 Val Arg Ser Ser Ala His Val Val Phe Gly Gly 35 40 <210> 2592 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2592 Cys Ser Tyr Ala Gly Ser Tyr Thr Phe Gly Tyr Val Phe 1 5 10 <210> 2593 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2593 cgcttctctg gctccaagtc tggcaacgcg gcctccctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cggttacgtc 120 ttcggaact 129 <210> 2594 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2594 Arg Phe Ser Gly Ser Lys Ser Gly Asn Ala Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Gly Tyr Val Phe Gly Thr 35 40 <210> 2595 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2595 cgcttctctg gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct 60 gaggatgagg ctgattatta ctgctgctca tatgcaggca gctacacttt cggttatgtc 120 ttcggaact 129 <210> 2596 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2596 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Tyr Thr Phe Gly Tyr Val Phe Gly Thr 35 40 <210> 2597 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2597 ggggtttcta atcgcttctc tggctccaag tctggcaaca cggcctccct gtcaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggta 120 ttcggcggt 129 <210> 2598 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2598 ggggtttcta atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccggg ctgaggacga ggctgattat tactgctgct catatgcagg tagttgggta 120 ttcgacgga 129 <210> 2599 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2599 Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Arg Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Ser Trp Val Phe Asp Gly 35 40 <210> 2600 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2600 Cys Ser Tyr Ala Gly Val Gly Thr Tyr Val Phe 1 5 10 <210> 2601 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2601 tctattcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtgttgg cacttatgtc 120 ttcggaatt 129 <210> 2602 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2602 Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Val Gly Thr Tyr Val Phe Gly Ile 35 40 <210> 2603 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2603 tctattcgct tctctggctc caaggctggc aacacggcct ccctgacatt ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtgttgg cacttatgtc 120 ttcggaatt 129 <210> 2604 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2604 Ser Ile Arg Phe Ser Gly Ser Lys Ala Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Phe Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Val Gly Thr Tyr Val Phe Gly Ile 35 40 <210> 2605 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2605 Cys Ser Tyr Ala Gly Gly Phe Thr Leu Leu Phe 1 5 10 <210> 2606 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2606 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctggcg atgaggctga ttattactgc tgctcgtatg caggtggttt cactttactt 120 tttggcgga 129 <210> 2607 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2607 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Gly Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Gly Phe Thr Leu Leu Phe Gly Gly 35 40 <210> 2608 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2608 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgacg acgaggctga ttattactgc tgctcgtatg caggtggttt cactttactt 120 tttggcgga 129 <210> 2609 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2609 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Gly Phe Thr Leu Leu Phe Gly Gly 35 40 <210> 2610 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2610 Cys Ser Tyr Ala Gly Ser Ser Thr Asp Val Phe 1 5 10 <210> 2611 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2611 tctaatcgct tctctggctc caagtctggt aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattgctgc tgctcatatg caggtagtag cacggatgtc 120 ttcggaact 129 <210> 2612 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2612 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Cys Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Asp Val Phe Gly Thr 35 40 <210> 2613 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2613 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtag cacggatgtc 120 ttcggaact 129 <210> 2614 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2614 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Asp Val Phe Gly Thr 35 40 <210> 2615 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2615 Cys Ser Tyr Thr Arg Ser Arg Gly Val Val Phe 1 5 10 <210> 2616 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2616 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatata cacgtagtag gggggtggta 120 ttcggcgga 129 <210> 2617 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2617 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Arg Ser Arg Gly Val Val Phe Gly Gly 35 40 <210> 2618 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2618 tctaatcgct tctctggctc caagtctggc aacacggccc ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatata cacgtagtag gggggtggta 120 ttcggcgga 129 <210> 2619 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2619 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Pro Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Arg Ser Arg Gly Val Val Phe Gly Gly 35 40 <210> 2620 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2620 Cys Ser Tyr Ala Gly Ser Ser Thr Ser Gly Val Phe 1 5 10 <210> 2621 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2621 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttcgggggta 120 ttcggcgga 129 <210> 2622 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2622 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Gly Val Phe Gly Gly 35 40 <210> 2623 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2623 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac ttcgggggta 120 ttcggcgga 129 <210> 2624 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2624 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Ser Gly Val Phe Gly Gly 35 40 <210> 2625 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2625 Cys Ser Tyr Ala Gly Ser Ser Thr Tyr Ile Phe 1 5 10 <210> 2626 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2626 tgtaatcgct tctgtggctc caagtctggc aacacggcct ccctgacaat ctctggactc 60 caggctgagg acgaggctga atattactgc tgctcatatg caggtagtag cacttatatc 120 ttcggaact 129 <210> 2627 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2627 Cys Asn Arg Phe Cys Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Glu Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Ile Phe Gly Thr 35 40 <210> 2628 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2628 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctggactc 60 caggctgagg acgaggctga atattactgc tgctcatatg caggtagtag cacttatatc 120 ttcggaact 129 <210> 2629 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2629 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Glu Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Ser Thr Tyr Ile Phe Gly Thr 35 40 <210> 2630 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2630 Cys Ser Tyr Ala Gly Ser Tyr Ser Phe Leu Phe 1 5 10 <210> 2631 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2631 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctcttggctc 60 cagtctgagg atgaggctga ttattactgc tgttcatatg caggcagtta tagtttctta 120 ttcggcgga 129 <210> 2632 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2632 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ser Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Phe Leu Phe Gly Gly 35 40 <210> 2633 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2633 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgttcatatg caggcagtta tagtttctta 120 ttcggcgga 129 <210> 2634 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2634 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Tyr Ser Phe Leu Phe Gly Gly 35 40 <210> 2635 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2635 Cys Ser Tyr Ala Gly Ser Tyr Thr Gly Val Val Phe 1 5 10 <210> 2636 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2636 gatcgcttct ctggctccaa gtcttgcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac aggggttgta 120 ttcggcgga 129 <210> 2637 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2637 Asp Arg Phe Ser Gly Ser Lys Ser Cys Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Gly Val Val Phe Gly Gly 35 40 <210> 2638 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2638 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac aggggtggta 120 ttcggcgga 129 <210> 2639 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2639 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr Gly Val Val Phe Gly Gly 35 40 <210> 2640 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2640 Cys Ser Tyr Gly Asp Thr Ser Pro Ala Ile Phe 1 5 10 <210> 2641 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2641 tctgatcgct tctctggctc caagtctggc aatacggcct ccctggcaat ctctgggctc 60 cagactgagg acgaggctga ttatttctgc tgctcatatg gcgatactag ccccgcgata 120 ttcggcgga 129 <210> 2642 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2642 Ser Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala 1 5 10 15 Ile Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Gly Asp Thr Ser Pro Ala Ile Phe Gly Gly 35 40 <210> 2643 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2643 tctgatcgct tctctgactc caagtctggc aatacggcct ccctggcaat ctctgggctc 60 cagactgagg acgaggctga ttatttctgc tgctcatatg gagatactag ccccgcgata 120 ttcggcgga 129 <210> 2644 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2644 Ser Asp Arg Phe Ser Asp Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala 1 5 10 15 Ile Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Gly Asp Thr Ser Pro Ala Ile Phe Gly Gly 35 40 <210> 2645 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2645 Cys Ser Tyr Ala Gly Cys Ser Val Val Phe 1 5 10 <210> 2646 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2646 gtttcttatc gcttctctgg ctccaagtct ggcaacacag cctccctgac aatctctggg 60 atccaggctg aggacgaggc tgattattat tgttgttcat atgcaggttg tagcgtggta 120 ttcggcgga 129 <210> 2647 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2647 Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Ile Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Cys Ser Val Val Phe Gly Gly 35 40 <210> 2648 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2648 gtttctattc gcttctctgg ctccaagtct ggcaacacag cctccctgac aatctctggg 60 atccaggctg aggacgaggc tgattattat tgttgttcat atgcaggttg tagcgtggta 120 ttcggcgga 129 <210> 2649 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2649 Val Ser Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu 1 5 10 15 Thr Ile Ser Gly Ile Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys 20 25 30 Ser Tyr Ala Gly Cys Ser Val Val Phe Gly Gly 35 40 <210> 2650 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2650 Cys Ser His Ala Gly Arg Tyr Pro Tyr Val Phe 1 5 10 <210> 2651 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2651 cctgatcgct tctctggctc caagtctggc aactcggcct ccctgtccat ctctgggctc 60 caggctgaag atgaggctga ttattattgc tgctcacatg caggcaggta cccttatgtc 120 ttcggaact 129 <210> 2652 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2652 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 His Ala Gly Arg Tyr Pro Tyr Val Phe Gly Thr 35 40 <210> 2653 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2653 cctgatcgct tctctggctc caagtctggc aacacggcct ccctggccat ctctgggctc 60 caggctgaag atgaggctga ttattattgc tgctcacatg caggcaggta cccttatgtc 120 ttcggaact 129 <210> 2654 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2654 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 His Ala Gly Arg Tyr Pro Tyr Val Phe Gly Thr 35 40 <210> 2655 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2655 Cys Ser Tyr Ala Gly Ser Ser Ser Phe Val Val Phe 1 5 10 <210> 2656 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2656 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgactatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagctc tttcgtggta 120 ttcggcgga 129 <210> 2657 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2657 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Ser Phe Val Val Phe Gly Gly 35 40 <210> 2658 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2658 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcag tttcgtggta 120 ttcggggga 129 <210> 2659 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2659 Cys Ser Tyr Ala Gly Ser Thr Thr Tyr Val Phe 1 5 10 <210> 2660 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2660 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtac cacctatgtc 120 ttccgaact 129 <210> 2661 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2661 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Thr Thr Tyr Val Phe Arg Thr 35 40 <210> 2662 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2662 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ctattactgc tgctcatatg caggtagtac cacttatgtc 120 ttcggaacc 129 <210> 2663 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2663 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Thr Thr Tyr Val Phe Gly Thr 35 40 <210> 2664 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2664 Cys Ser Tyr Thr Gly Ser His Thr Arg Val Phe 1 5 10 <210> 2665 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2665 cctgatcggc tctctggctg caagtctggc aactcggcct ccctgagcat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatata caggcagcca cacccgtgta 120 ttcggcgga 129 <210> 2666 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2666 Pro Asp Arg Leu Ser Gly Cys Lys Ser Gly Asn Ser Ala Ser Leu Ser 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Gly Ser His Thr Arg Val Phe Gly Gly 35 40 <210> 2667 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2667 cctgatcggc tctctggctg caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattactgc tgctcatata caggcagcca cacccgtgta 120 ttcggcgga 129 <210> 2668 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2668 Pro Asp Arg Leu Ser Gly Cys Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Gly Ser His Thr Arg Val Phe Gly Gly 35 40 <210> 2669 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2669 Cys Ser Tyr Ala Gly Ser Tyr Thr His Tyr Val Phe 1 5 10 <210> 2670 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2670 gttcgcttct ctggctcgaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ccactatgtc 120 ttcggaact 129 <210> 2671 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2671 Val Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Tyr Val Phe Gly Thr 35 40 <210> 2672 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2672 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag 60 gctgaggatg aggctgatta ttactgctgc tcatatgcag gcagctacac ccactatgtc 120 ttcggaact 129 <210> 2673 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2673 Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Tyr Thr His Tyr Val Phe Gly Thr 35 40 <210> 2674 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2674 Cys Ser Tyr Thr Arg Pro Thr Pro Gly Tyr Val Phe 1 5 10 <210> 2675 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2675 gatggcttct ctgggtccat gtctggcagc acggcctccc tgaccatctc tgggctccag 60 cctgaagacg aggctgatta ttactgctgc tcatatacaa gacccactcc cggttatgtc 120 ttcgggact 129 <210> 2676 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2676 Asp Gly Phe Ser Gly Ser Met Ser Gly Ser Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Pro Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Thr Arg Pro Thr Pro Gly Tyr Val Phe Gly Thr 35 40 <210> 2677 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2677 gatcgcttct ctgggtccaa gtctggcagc acggcctccc tgaccatctc tgggctccag 60 cctgaagacg aggctgatta ttactgctgc tcatatacaa gacccactcc cggttatgtc 120 ttcgggact 129 <210> 2678 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2678 Asp Arg Phe Ser Gly Ser Lys Ser Gly Ser Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Pro Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Thr Arg Pro Thr Pro Gly Tyr Val Phe Gly Thr 35 40 <210> 2679 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2679 Cys Ser Phe Val Ser Gly Asn Ser Tyr Val Phe 1 5 10 <210> 2680 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2680 tctaatcgct tctctggctc caagtctggc aactcggcct ccctgacaat ctcttggctc 60 caggctgacg acgaggctga ttattactgc tgctcgtttg taagtggtaa cagttatgtc 120 ttcggaact 129 <210> 2681 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2681 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Ser Ala Ser Leu Thr 1 5 10 15 Ile Ser Trp Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Val Ser Gly Asn Ser Tyr Val Phe Gly Thr 35 40 <210> 2682 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2682 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgacg acgaggctga ttattactgc tgctcgtttg taagtggtaa cagttatgtc 120 ttcggaact 129 <210> 2683 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2683 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Asp Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Phe Val Ser Gly Asn Ser Tyr Val Phe Gly Thr 35 40 <210> 2684 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2684 Cys Ser Tyr Ala Gly Ser Ser Thr Phe Met Trp Tyr Ser 1 5 10 <210> 2685 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2685 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt tatgtggtat 120 tcggcggag 129 <210> 2686 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2686 Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser 1 5 10 15 Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala 20 25 30 Gly Ser Ser Thr Phe Met Trp Tyr Ser Ala Glu 35 40 <210> 2687 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2687 cgcttctctg gctccaagtc tggcaacacg gcctccctga caatctctgg gctccaggct 60 gaggacgagg ctgattatta ctgctgctca tatgcaggta gtagcacttt catgtggtat 120 tcggcggag 129 <210> 2688 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2688 Cys Ser Tyr Ala Gly Gly Lys Thr Gly Val Phe 1 5 10 <210> 2689 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2689 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctt 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtggtaa aacgggggtc 120 ttcggaact 129 <210> 2690 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2690 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Gly Lys Thr Gly Val Phe Gly Thr 35 40 <210> 2691 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2691 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctt 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtggtaa aacgggggtc 120 ttcggaact 129 <210> 2692 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2692 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Gly Lys Thr Gly Val Phe Gly Thr 35 40 <210> 2693 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2693 Cys Ser Tyr Ala Asp Ser Ser Ser Phe Tyr Val Phe 1 5 10 <210> 2694 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2694 aatcgcttct ctggctgcaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgttgc tcatatgcag atagtagctc tttctatgtc 120 ttcggaact 129 <210> 2695 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2695 Asn Arg Phe Ser Gly Cys Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Asp Ser Ser Ser Phe Tyr Val Phe Gly Thr 35 40 <210> 2696 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2696 aatcgcttct ctggctccaa gtctggcaac acggcctccc agacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgttgc tcatatgcag atagtagctc tttctatgtc 120 ttcggaact 129 <210> 2697 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2697 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Gln Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Asp Ser Ser Ser Phe Tyr Val Phe Gly Thr 35 40 <210> 2698 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2698 Cys Ser Tyr Ala Gly Ser Ser Thr Asn Val Val Phe 1 5 10 <210> 2699 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2699 aatcgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac taatgtggta 120 ttcggcgga 129 <210> 2700 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2700 Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Asn Val Val Phe Gly Gly 35 40 <210> 2701 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2701 atccgcttct ctggctccaa gtctggcaac acggcctccc tgacaatctc tgggctccag 60 gctgaggacg aggctgatta ttactgctgc tcatatgcag gtagtagcac taatgtggta 120 ttcggcgga 129 <210> 2702 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2702 Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile 1 5 10 15 Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr 20 25 30 Ala Gly Ser Ser Thr Asn Val Val Phe Gly Gly 35 40 <210> 2703 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2703 Cys Ser Tyr Thr Ser Ser Arg Thr Gly Val Phe 1 5 10 <210> 2704 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2704 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcataca caagtagcag aactggggtg 120 ttcggcggg 129 <210> 2705 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2705 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Ser Ser Arg Thr Gly Val Phe Gly Gly 35 40 <210> 2706 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2706 ctaatccgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcataca caagtagcag aactggggtg 120 ttcggcggg 129 <210> 2707 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2707 Leu Ile Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Thr Ser Ser Arg Thr Gly Val Phe Gly Gly 35 40 <210> 2708 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2708 Cys Ser Tyr Ala Gly Phe Tyr Val Phe 1 5 <210> 2709 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2709 ggggtttctt atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tttttatgtc 120 ttcggaact 129 <210> 2710 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2710 Gly Val Ser Tyr Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Phe Tyr Val Phe Gly Thr 35 40 <210> 2711 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2711 ggggtttcta atcgcttctc tggctccaag tctggcaaca cggcctccct gacaatctct 60 gggctccagg ctgaggacga ggctgattat tactgctgct catatgcagg tttttatgtc 120 ttcggaact 129 <210> 2712 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2712 Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser 1 5 10 15 Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys 20 25 30 Cys Ser Tyr Ala Gly Phe Tyr Val Phe Gly Thr 35 40 <210> 2713 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2713 Cys Ser Tyr Ala Gly Arg Asp Thr Val Ala Phe 1 5 10 <210> 2714 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2714 cctgatcgct tctctggctc caagtctgtc aacactgcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattattgc tgctcatatg caggcagaga cactgtggca 120 ttcggcgga 129 <210> 2715 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2715 Pro Asp Arg Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Arg Asp Thr Val Ala Phe Gly Gly 35 40 <210> 2716 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2716 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccat ctctgggctc 60 caggctgagg atgaggctga ttattattgc tgctcatatg caggcagaga cactgtggca 120 ttcggcgga 129 <210> 2717 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2717 Pro Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Arg Asp Thr Val Ala Phe Gly Gly 35 40 <210> 2718 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2718 Cys Ser Tyr Ala Gly Ser Thr Thr Val Val Phe 1 5 10 <210> 2719 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2719 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtac cactgtcgta 120 ttcggcggc 129 <210> 2720 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2720 Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr 1 5 10 15 Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser 20 25 30 Tyr Ala Gly Ser Thr Thr Val Val Phe Gly Gly 35 40 <210> 2721 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2721 tctaatcgct tctctggctc caagtctggc aacacggcct ccctgacaat ctctgggctc 60 caggctgagg acgaggctga ttattactgc tgctcatatg caggtagtac cactgtcgta 120 ttcggcgga 129 <210> 2722 <211> 6 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2722 Cys Ser Phe Ser Val Phe 1 5 <210> 2723 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2723 cggccctcag gggtttctaa tcgcttctct ggctccaagt ctcgcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagtgtc 120 ttcggaact 129 <210> 2724 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2724 Arg Pro Ser Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Arg Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Ser Val Phe Gly Thr 35 40 <210> 2725 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2725 cggccatcag gggtttctaa tcgcttctct ggctccaagt ctggcaacac ggcctccctg 60 acaatctctg ggctccaggc tgaggacgag gctgattatt actgctgctc atttagtgtc 120 ttcggaact 129 <210> 2726 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2726 Arg Pro Ser Gly Val Ser Asn Arg Phe Ser Gly Ser Lys Ser Gly Asn 1 5 10 15 Thr Ala Ser Leu Thr Ile Ser Gly Leu Gln Ala Glu Asp Glu Ala Asp 20 25 30 Tyr Tyr Cys Cys Ser Phe Ser Val Phe Gly Thr 35 40 <210> 2727 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2727 Cys Ser Tyr Gly Asp Thr Arg Pro Val Ile Phe 1 5 10 <210> 2728 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2728 tctgatcgct tctctggctc caagtctgtc aatacggcct ccctggcaat ctctgggctc 60 cagactgagg acgaggctga ttatttctgc tgctcatatg gagatactag acccgtgata 120 ttcggcgga 129 <210> 2729 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2729 Ser Asp Arg Phe Ser Gly Ser Lys Ser Val Asn Thr Ala Ser Leu Ala 1 5 10 15 Ile Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Gly Asp Thr Arg Pro Val Ile Phe Gly Gly 35 40 <210> 2730 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2730 tctgatcgct tctctggctc caagtctggc aatacggcct ccctggcaat ctctgggctc 60 cagactgagg acgaggctga ttatttctgc tgctcatatg gagatactcg ccccgtgata 120 ttcggcggc 129 <210> 2731 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2731 Ser Asp Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Ala 1 5 10 15 Ile Ser Gly Leu Gln Thr Glu Asp Glu Ala Asp Tyr Phe Cys Cys Ser 20 25 30 Tyr Gly Asp Thr Arg Pro Val Ile Phe Gly Gly 35 40 <210> 2732 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2732 Cys Ala Arg Leu Leu Gly Gly Trp Gly Gly Gln Thr Trp 1 5 10 <210> 2733 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2733 ttcatctcca tacacaaccc caagaacacg ctttatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg ggtggggagg tcagacttgg 120 ggccaggga 129 <210> 2734 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2734 Phe Ile Ser Ile His Asn Pro Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu 20 25 30 Gly Gly Trp Gly Gly Gln Thr Trp Gly Gln Gly 35 40 <210> 2735 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2735 ttcatctcca gagacaacgc caagaacacg ctgtatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg ggtggggagg tcagacttgg 120 ggccaggga 129 <210> 2736 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2736 Phe Ile Ser Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu 20 25 30 Gly Gly Trp Gly Gly Gln Thr Trp Gly Gln Gly 35 40 <210> 2737 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2737 atcatctcca tagacaacgc caagaacacg ctgtatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg ggtggggagg tcagacttgg 120 ggccaggga 129 <210> 2738 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2738 Ile Ile Ser Ile Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu 20 25 30 Gly Gly Trp Gly Gly Gln Thr Trp Gly Gln Gly 35 40 <210> 2739 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2739 atcatctcca tacacaacgc caagaacacg ctgtatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg ggtggggagg tcagacttgg 120 ggccaggga 129 <210> 2740 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2740 Ile Ile Ser Ile His Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu 20 25 30 Gly Gly Trp Gly Gly Gln Thr Trp Gly Gln Gly 35 40 <210> 2741 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2741 atcatctcca tacacaacgc caagaacacg atgtatttgc aaatcaacag tcttagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg ggtggggagg tcagacttgg 120 ggccaggga 129 <210> 2742 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2742 Ile Ile Ser Ile His Asn Ala Lys Asn Thr Met Tyr Leu Gln Ile Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu 20 25 30 Gly Gly Trp Gly Gly Gln Thr Trp Gly Gln Gly 35 40 <210> 2743 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2743 atcatctcca gagacaacgc caagaacacg ctgtatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg ggtggggagg tcagacttgg 120 ggccaggga 129 <210> 2744 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2744 Ile Ile Ser Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu 20 25 30 Gly Gly Trp Gly Gly Gln Thr Trp Gly Gln Gly 35 40 <210> 2745 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2745 atcatctcca gagacaacgc caagaacacg ctgtatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctggggg ggtggggagg tcagacttgg 120 ggccaggga 129 <210> 2746 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2746 atcatctcca gagacaaccc caagaacacg ctgtatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg ggtggggagg tcagacttgg 120 ggccaggga 129 <210> 2747 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2747 Ile Ile Ser Arg Asp Asn Pro Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu 20 25 30 Gly Gly Trp Gly Gly Gln Thr Trp Gly Gln Gly 35 40 <210> 2748 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2748 atcatctcca gacacaacgc caagaacacg ctgtatttgc aaatgaacag tcttagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg ggtggggagg tcagacttgg 120 ggccaggga 129 <210> 2749 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2749 Ile Ile Ser Arg His Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu 20 25 30 Gly Gly Trp Gly Gly Gln Thr Trp Gly Gln Gly 35 40 <210> 2750 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2750 atcatctcca gacacaacgc caagaacacg ctgtatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg ggtggggagg tcagacttgg 120 ggccaggga 129 <210> 2751 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2751 atcatctcca gacacaacgc caagaacacg ctgtatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctggggg ggtggggagg tcagacttgg 120 ggccaggga 129 <210> 2752 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2752 atcatctcca gacacaaccc caagaacacg ctgtatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg ggtggggagg tcagacttgg 120 ggccaggga 129 <210> 2753 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2753 Ile Ile Ser Arg His Asn Pro Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu 20 25 30 Gly Gly Trp Gly Gly Gln Thr Trp Gly Gln Gly 35 40 <210> 2754 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2754 Cys Ala Arg Gly Trp Gly Phe Gly Glu Leu Trp Asp Tyr Trp 1 5 10 <210> 2755 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2755 ttctccagag aaaatgccaa gaactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagaggt tgggggttcg gggagttgtg ggactactgg 120 ggccaggga 129 <210> 2756 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2756 Phe Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Trp Gly 20 25 30 Phe Gly Glu Leu Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 2757 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2757 atctccatag aaaatgccaa gaactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagaggt tgggggttcg gggagttgtg ggactactgg 120 ggccaggga 129 <210> 2758 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2758 Ile Ser Ile Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Trp Gly 20 25 30 Phe Gly Glu Leu Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 2759 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2759 atctccatac aaaatgccaa gaactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagaggt tgggggttcg gggagttgtg ggactactgg 120 ggccaggga 129 <210> 2760 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2760 Ile Ser Ile Gln Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Trp Gly 20 25 30 Phe Gly Glu Leu Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 2761 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2761 atctccatac aaaatcccaa gaactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagaggt tgggggttcg gggagttgtg ggactactgg 120 ggccaggga 129 <210> 2762 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2762 Ile Ser Ile Gln Asn Pro Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Trp Gly 20 25 30 Phe Gly Glu Leu Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 2763 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2763 atctccagag aaaatgccaa gaactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagaggt tgggggttcg gggagttgtg ggactactgg 120 ggccaggga 129 <210> 2764 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2764 Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Trp Gly 20 25 30 Phe Gly Glu Leu Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 2765 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2765 atctccagag aaaatgccaa caactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagaggt tgggggttcg gggagttgtg ggactactgg 120 ggccaggga 129 <210> 2766 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2766 Ile Ser Arg Glu Asn Ala Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Trp Gly 20 25 30 Phe Gly Glu Leu Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 2767 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2767 atctccagag aaaatcccaa gaactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagaggt tgggggttcg gggagttgtg ggactactgg 120 ggccaggga 129 <210> 2768 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2768 Ile Ser Arg Glu Asn Pro Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Trp Gly 20 25 30 Phe Gly Glu Leu Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 2769 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2769 atctccagag aaaatcccaa caactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagaggt tgggggttcg gggagttgtg ggactactgg 120 ggccaggga 129 <210> 2770 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2770 Ile Ser Arg Glu Asn Pro Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Trp Gly 20 25 30 Phe Gly Glu Leu Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 2771 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2771 atctccagac aaaatgccaa gaactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagaggt tgggggttcg gggagttgtg ggactactgg 120 ggccaggga 129 <210> 2772 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2772 Ile Ser Arg Gln Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Trp Gly 20 25 30 Phe Gly Glu Leu Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 2773 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2773 atctccagac aaaatcccaa gaactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagaggt tgggggttcg gggagttgtg ggactactgg 120 ggccaggga 129 <210> 2774 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2774 Ile Ser Arg Gln Asn Pro Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Trp Gly 20 25 30 Phe Gly Glu Leu Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 2775 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2775 Cys Ala His Arg Arg Val Ala Leu Ala Thr Arg Phe Asp Ile Trp 1 5 10 15 <210> 2776 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2776 actatggacg cctccaaaaa cctggtggtc ctcacaatgg ccaacatgga ccctgaggac 60 acggccacat attattgtgc acacagaaga gtggcgttgg cgactcgttt tgatatctgg 120 ggccaaggg 129 <210> 2777 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2777 Thr Met Asp Ala Ser Lys Asn Leu Val Val Leu Thr Met Ala Asn Met 1 5 10 15 Asp Pro Glu Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg Val Ala 20 25 30 Leu Ala Thr Arg Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 2778 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2778 actatggacg actccaaaaa ccaggtggtc ctcacaatgg ccaacatgga ccctgaggac 60 acggccacat attattgtgc acacagaaga gtggcgttgg cgactcgttt tgatatctgg 120 ggccaaggg 129 <210> 2779 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2779 Thr Met Asp Asp Ser Lys Asn Gln Val Val Leu Thr Met Ala Asn Met 1 5 10 15 Asp Pro Glu Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg Val Ala 20 25 30 Leu Ala Thr Arg Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 2780 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2780 actaaggact actccaaaaa ccaggtggtc ctcacaatgg ccaacatgga ccctgaggac 60 acggccacat attactgtgc acacagaaga gtggcgttgg cgactcgttt tgatatctgg 120 ggccaaggg 129 <210> 2781 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2781 Thr Lys Asp Tyr Ser Lys Asn Gln Val Val Leu Thr Met Ala Asn Met 1 5 10 15 Asp Pro Glu Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg Val Ala 20 25 30 Leu Ala Thr Arg Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 2782 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2782 actaaggacg cctccaaaaa ccaggtggtc ctcacaatgg ccaacatgga ccctgaggac 60 acggccacat attattgtgc acacagaaga gtggcgttgg cgactcgttt tgatatctgg 120 ggccaaggg 129 <210> 2783 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2783 Thr Lys Asp Ala Ser Lys Asn Gln Val Val Leu Thr Met Ala Asn Met 1 5 10 15 Asp Pro Glu Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg Val Ala 20 25 30 Leu Ala Thr Arg Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 2784 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2784 actaaggacg actccaaaaa cctggtggtc ctcacaatgg ccaacatgga ccctgaggac 60 acggccacat attattgtgc acacagaaga gtggcgttgg cgactcgttt tgatatctgg 120 ggccaaggg 129 <210> 2785 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2785 Thr Lys Asp Asp Ser Lys Asn Leu Val Val Leu Thr Met Ala Asn Met 1 5 10 15 Asp Pro Glu Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg Val Ala 20 25 30 Leu Ala Thr Arg Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 2786 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2786 actaaggaca cctccaaaaa ccaggtggtc ctcacaatgg ccaacatgga ccctgaggac 60 acggccacat attactgtgc acacagaaga gtggcgttgg cgactcgttt tgatatctgg 120 ggccaaggg 129 <210> 2787 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2787 Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Ala Asn Met 1 5 10 15 Asp Pro Glu Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg Val Ala 20 25 30 Leu Ala Thr Arg Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 2788 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2788 acaaaggaca cctccaagag ccaggtggtc ctcacaatgg ccaatatgga ccctgacgac 60 acggccacat attactgtgc acacagaaga gtggcgttgg cgactcgttt tgatatttgg 120 ggccaaggg 129 <210> 2789 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2789 Thr Lys Asp Thr Ser Lys Ser Gln Val Val Leu Thr Met Ala Asn Met 1 5 10 15 Asp Pro Asp Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg Val Ala 20 25 30 Leu Ala Thr Arg Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 2790 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2790 ctaacgcacg cctccaaaaa ccaggtggtc ctcacaatgg ccaacatgga ccctgaggac 60 acggccacat attattgtgc acacagaaga gtggcgttgg cgactcgttt tgatatctgg 120 ggccaaggg 129 <210> 2791 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2791 Leu Thr His Ala Ser Lys Asn Gln Val Val Leu Thr Met Ala Asn Met 1 5 10 15 Asp Pro Glu Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg Val Ala 20 25 30 Leu Ala Thr Arg Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 2792 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2792 actatggacg cctccaaaaa ccaggtggtc ctcacaatgg ccaacatgga ccctgaggac 60 acggccacat attattgtgc acacagaaga gtggcgttgg cgactcgttt tgatatctgg 120 ggccaaggg 129 <210> 2793 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2793 Thr Met Asp Ala Ser Lys Asn Gln Val Val Leu Thr Met Ala Asn Met 1 5 10 15 Asp Pro Glu Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg Val Ala 20 25 30 Leu Ala Thr Arg Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 2794 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2794 Cys Ala His Gly Val Gly Gly Trp Asp Gly Gln Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 2795 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2795 aaggacacct ccaaaagcca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cggtgttgga ggctgggatg ggcagtactt tgactactgg 120 ggccaagga 129 <210> 2796 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2796 Lys Asp Thr Ser Lys Ser Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Val Gly Gly Trp 20 25 30 Asp Gly Gln Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2797 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2797 aaggactcct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cggtgttggc ggctgggatg ggcagtactt tgactactgg 120 ggccaggga 129 <210> 2798 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2798 Lys Asp Ser Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Val Gly Gly Trp 20 25 30 Asp Gly Gln Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2799 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2799 aaggacacgt ccaaaaacca ggtggtcctt tcaatgacca acatggaccc tgaggacaca 60 gccacatatt actgtgcaca cggtgttgga ggctgggatg ggcaatactt tgactactgg 120 ggccaggga 129 <210> 2800 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2800 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Ser Met Thr Asn Met Asp 1 5 10 15 Pro Glu Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Val Gly Gly Trp 20 25 30 Asp Gly Gln Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2801 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2801 aaggacacgt ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cggtgttgga ggctgggatg ggcagtactt tgactactgg 120 ggccaggga 129 <210> 2802 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2802 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Val Gly Gly Trp 20 25 30 Asp Gly Gln Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2803 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2803 aaggacacct ccaaaaacca ggttgtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cggtgttgga ggctgggatg ggcaatactt tgactactgg 120 ggccaggga 129 <210> 2804 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2804 aaggacacct ccaaaaacca ggtggtcctt agaatgacca acatggaccc tgcggacaca 60 gccacatatt actgtgcaca cggtgttgga ggctgggatg ggcagtattt tgactactgg 120 gggcaggga 129 <210> 2805 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2805 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Arg Met Thr Asn Met Asp 1 5 10 15 Pro Ala Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Val Gly Gly Trp 20 25 30 Asp Gly Gln Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2806 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2806 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cggtgttgga ggctgggatg ggcagtactt tgactactgg 120 ggccaggga 129 <210> 2807 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2807 aaggacacct ccaaaaacca ggtggtccta acaatgacca acatggaccc tgtagacaca 60 gccacatatt actgtgcaca cggtgttgga ggctgggatg ggcagtactt tgactactgg 120 ggccaggga 129 <210> 2808 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2808 aaggacaact cgaaaaacca ggtggtcctt agattgaccg acatggaccc tgcggacaca 60 gccacatatt actgtgcaca cggtgttgga ggctgggatg ggcagtattt tgactactgg 120 gggcaggga 129 <210> 2809 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2809 Lys Asp Asn Ser Lys Asn Gln Val Val Leu Arg Leu Thr Asp Met Asp 1 5 10 15 Pro Ala Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Val Gly Gly Trp 20 25 30 Asp Gly Gln Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2810 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2810 Cys Gln Tyr Gly Ser Gly Ser Tyr Asp Trp Phe Asp Pro Trp 1 5 10 <210> 2811 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2811 atctccttag atgattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tcaatatggt tcggggagtt atgactggtt cgacccctgg 120 ggccaggga 129 <210> 2812 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2812 Ile Ser Leu Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Gln Tyr Gly Ser Gly 20 25 30 Ser Tyr Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 2813 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2813 atctccatat ttcattcaaa gaacacggcg tatctgcaaa tgaacagcct taaaaccgag 60 gacacggccg tgtattactg tcaatatggt tcggggagtt atgactggtt cgacccctgg 120 ggccaggga 129 <210> 2814 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2814 Ile Ser Ile Phe His Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Gln Tyr Gly Ser Gly 20 25 30 Ser Tyr Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 2815 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2815 atctccatat atgattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tcaatatggt tcggggagtt atgactggtt cgacccctgg 120 ggccaggga 129 <210> 2816 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2816 Ile Ser Ile Tyr Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Gln Tyr Gly Ser Gly 20 25 30 Ser Tyr Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 2817 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2817 atctccatag attattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tcaatatggt tcggggagtt atgactggtt cgacccctgg 120 ggccaggga 129 <210> 2818 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2818 Ile Ser Ile Asp Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Gln Tyr Gly Ser Gly 20 25 30 Ser Tyr Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 2819 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2819 atctccatag atcattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tcaatatggt tcggggagtt atgactggtt cgacccctgg 120 ggccaggga 129 <210> 2820 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2820 Ile Ser Ile Asp His Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Gln Tyr Gly Ser Gly 20 25 30 Ser Tyr Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 2821 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2821 atctccagag attattcaaa caacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tcaatatggt tcggggagtt atgactggtt cgacccctgg 120 ggccaggga 129 <210> 2822 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2822 Ile Ser Arg Asp Tyr Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Gln Tyr Gly Ser Gly 20 25 30 Ser Tyr Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 2823 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2823 atctccagag atgattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tcaatatggt tcggggagtt atgactggtt cgacccctgg 120 ggccaggga 129 <210> 2824 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2824 Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Gln Tyr Gly Ser Gly 20 25 30 Ser Tyr Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 2825 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2825 atctccagag atcattcaaa caacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tcaatatggt tcggggagtt atgactggtt cgacccctgg 120 ggccaggga 129 <210> 2826 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2826 Ile Ser Arg Asp His Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Gln Tyr Gly Ser Gly 20 25 30 Ser Tyr Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 2827 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2827 tctccagaga tgattcaaag aaccacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tcaatatggt tcggggagtt atgactggtt cgacccctgg 120 ggccaggga 129 <210> 2828 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2828 Ser Pro Glu Met Ile Gln Arg Thr Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Gln Tyr Gly Ser Gly 20 25 30 Ser Tyr Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 2829 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2829 Cys Thr Arg Pro Pro Tyr Gly Asp Tyr Gly Asp Tyr Trp 1 5 10 <210> 2830 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2830 accatctcca tatatgattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga cccccctacg gtgactacgg tgactactgg 120 ggccaggga 129 <210> 2831 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2831 Thr Ile Ser Ile Tyr Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Pro Pro 20 25 30 Tyr Gly Asp Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 2832 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2832 accatctcca tagattattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga cccccctacg gtgactacgg tgactactgg 120 ggccaggga 129 <210> 2833 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2833 Thr Ile Ser Ile Asp Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Pro Pro 20 25 30 Tyr Gly Asp Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 2834 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2834 accatctcca gagattattc aaagaacacg gcgtatctgc aaatgaacag ccttaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga cccccctacg gtgactacgg tgactactgg 120 ggccaggga 129 <210> 2835 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2835 Thr Ile Ser Arg Asp Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Pro Pro 20 25 30 Tyr Gly Asp Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 2836 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2836 accatctcca gagattattc aaacaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga cccccctacg gtgactacgg tgactactgg 120 ggccaggga 129 <210> 2837 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2837 Thr Ile Ser Arg Asp Tyr Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Pro Pro 20 25 30 Tyr Gly Asp Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 2838 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2838 accatctcca gagatgattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga cccccctacg gtgactacgg tgactactgg 120 ggccaggga 129 <210> 2839 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2839 Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Pro Pro 20 25 30 Tyr Gly Asp Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 2840 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2840 aacatctcca tagatgattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga cccccctacg gtgactacgg tgactactgg 120 ggccaggga 129 <210> 2841 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2841 Asn Ile Ser Ile Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Pro Pro 20 25 30 Tyr Gly Asp Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 2842 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2842 aacatctcca gatatgattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga cccccctacg gtgactacgg tgactactgg 120 ggccaggga 129 <210> 2843 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2843 Asn Ile Ser Arg Tyr Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Pro Pro 20 25 30 Tyr Gly Asp Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 2844 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2844 aacatatcca gagatgattc aaagaacacg gcgtatctgc aaattaacag ccttaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga cccccctacg gtgactacgg tgactactgg 120 ggccaggga 129 <210> 2845 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2845 Asn Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Ile Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Pro Pro 20 25 30 Tyr Gly Asp Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 2846 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2846 ccatctccag agatgattca aagaaccacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga cccccctacg gtgactacgg tgactactgg 120 ggccaggga 129 <210> 2847 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2847 Pro Ser Pro Glu Met Ile Gln Arg Thr Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Pro Pro 20 25 30 Tyr Gly Asp Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 2848 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2848 Cys Ala Arg Glu Pro Thr Gly Gly Arg Leu Phe Asp Tyr Trp 1 5 10 <210> 2849 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2849 atcaacccag acacagccaa gaaccaattc tccctgcagc tggactctgt gactcccgag 60 gacacggctg tgtattactg tgcaagagaa ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 2850 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2850 Ile Asn Pro Asp Thr Ala Lys Asn Gln Phe Ser Leu Gln Leu Asp Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2851 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2851 atcaacccag acacagccaa caaccaattc tccctgcagc tggactctgt gactcccgag 60 gacacggctg tgtattactg tgcaagagaa ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 2852 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2852 Ile Asn Pro Asp Thr Ala Asn Asn Gln Phe Ser Leu Gln Leu Asp Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2853 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2853 atcaacccag acacagccaa caacaaattc tccctgcagc tggactctgt gactcccgag 60 gacacggctg tgtattactg tgcaagagaa ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 2854 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2854 Ile Asn Pro Asp Thr Ala Asn Asn Lys Phe Ser Leu Gln Leu Asp Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2855 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2855 atcaacccag acacacccaa caaccaattc tccctgcagc tggactctgt gactcccgag 60 gacacggctg tgtattactg tgcaagagaa ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 2856 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2856 Ile Asn Pro Asp Thr Pro Asn Asn Gln Phe Ser Leu Gln Leu Asp Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2857 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2857 atcaacccac acacagccaa gaaccaattc tccctgcagc tggactctgt gactcccgag 60 gacacggctg tgtattactg tgcaagagaa ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 2858 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2858 Ile Asn Pro His Thr Ala Lys Asn Gln Phe Ser Leu Gln Leu Asp Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2859 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2859 atcaacccac acacagccaa caaccaattc tccctgcagc tggactctgt gactcccgag 60 gacacggctg tgtattactg tgcaagagaa ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 2860 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2860 Ile Asn Pro His Thr Ala Asn Asn Gln Phe Ser Leu Gln Leu Asp Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2861 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2861 atcaacccac acacacccaa gaaccaattc tccctgcagc tggactctgt gactcccgag 60 gacacggctg tgtattactg tgcaagagaa ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 2862 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2862 Ile Asn Pro His Thr Pro Lys Asn Gln Phe Ser Leu Gln Leu Asp Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2863 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2863 atcaacccac acacacccaa caaccaattc tccctgcagc tggactctgt gactcccgag 60 gacacggctg tgtattactg tgcaagagaa ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 2864 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2864 Ile Asn Pro His Thr Pro Asn Asn Gln Phe Ser Leu Gln Leu Asp Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2865 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2865 Cys Ala His Ser Val Leu Thr Pro Thr Phe Ala Tyr Trp 1 5 10 <210> 2866 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2866 caccatcacc aaggacgact ccaaaaccag gtggtcctga cattgaccaa cctggaccct 60 gtggacacag ccacatattt ctgtgcacat tcggtgctta cgccgacttt tgcctattgg 120 ggccaggga 129 <210> 2867 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2867 His His His Gln Gly Arg Leu Gln Asn Gln Val Val Leu Thr Leu Thr 1 5 10 15 Asn Leu Asp Pro Val Asp Thr Ala Thr Tyr Phe Cys Ala His Ser Val 20 25 30 Leu Thr Pro Thr Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 2868 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2868 accatcacca tgcacgactc caaaaaccag gtggtcctga cattgaccaa cctggaccct 60 gtggacacag ccacatattt ctgtgcacat tcggtgctta cgccgacttt tgcctattgg 120 ggccaggga 129 <210> 2869 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2869 Thr Ile Thr Met His Asp Ser Lys Asn Gln Val Val Leu Thr Leu Thr 1 5 10 15 Asn Leu Asp Pro Val Asp Thr Ala Thr Tyr Phe Cys Ala His Ser Val 20 25 30 Leu Thr Pro Thr Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 2870 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2870 accatcacca cggacgactc caaaaaccag gtggtcctga cattgaccaa cctggaccct 60 gtggacacag ccacatattt ctgtgcacat tcggtgctta cgccgacttt tgcctattgg 120 ggccaggga 129 <210> 2871 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2871 Thr Ile Thr Thr Asp Asp Ser Lys Asn Gln Val Val Leu Thr Leu Thr 1 5 10 15 Asn Leu Asp Pro Val Asp Thr Ala Thr Tyr Phe Cys Ala His Ser Val 20 25 30 Leu Thr Pro Thr Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 2872 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2872 accatcacca cgcacgactc caaaaaccag gtggtcctga cattgaccaa cctggaccct 60 gtggacacag ccacatattt ctgtgcacat tcggtgctta cgccgacttt tgcctattgg 120 ggccaggga 129 <210> 2873 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2873 Thr Ile Thr Thr His Asp Ser Lys Asn Gln Val Val Leu Thr Leu Thr 1 5 10 15 Asn Leu Asp Pro Val Asp Thr Ala Thr Tyr Phe Cys Ala His Ser Val 20 25 30 Leu Thr Pro Thr Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 2874 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2874 accatcacca aggacgactc caaaaaccag gtggtcctga cattgaccaa cctggaccct 60 gtggacacag ccacatattt ctgtgcacat tcggtgctta cgccgacttt tgcctattgg 120 ggccaggga 129 <210> 2875 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2875 Thr Ile Thr Lys Asp Asp Ser Lys Asn Gln Val Val Leu Thr Leu Thr 1 5 10 15 Asn Leu Asp Pro Val Asp Thr Ala Thr Tyr Phe Cys Ala His Ser Val 20 25 30 Leu Thr Pro Thr Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 2876 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2876 accaacccca cggacgactc caaaaaccag gtggtcctga cattgaccaa cctggaccct 60 gtggacacag ccacatattt ctgtgcacat tcggtgctta cgccgacttt tgcctattgg 120 ggccaggga 129 <210> 2877 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2877 Thr Asn Pro Thr Asp Asp Ser Lys Asn Gln Val Val Leu Thr Leu Thr 1 5 10 15 Asn Leu Asp Pro Val Asp Thr Ala Thr Tyr Phe Cys Ala His Ser Val 20 25 30 Leu Thr Pro Thr Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 2878 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2878 accaacacca tgcacgactc caaaaaccag gtggtcctga cattgaccaa cctggaccct 60 gtggacacag ccacatattt ctgtgcacat tcggtgctta cgccgacttt tgcctattgg 120 ggccaggga 129 <210> 2879 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2879 Thr Asn Thr Met His Asp Ser Lys Asn Gln Val Val Leu Thr Leu Thr 1 5 10 15 Asn Leu Asp Pro Val Asp Thr Ala Thr Tyr Phe Cys Ala His Ser Val 20 25 30 Leu Thr Pro Thr Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 2880 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2880 ccatcaccaa ggcacgactc caaaaaccag gtggtcctga cattgaccaa cctggaccct 60 gtggacacag ccacatattt ctgtgcacat tcggtgctta cgccgacttt tgcctattgg 120 ggccaggga 129 <210> 2881 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2881 Pro Ser Pro Arg His Asp Ser Lys Asn Gln Val Val Leu Thr Leu Thr 1 5 10 15 Asn Leu Asp Pro Val Asp Thr Ala Thr Tyr Phe Cys Ala His Ser Val 20 25 30 Leu Thr Pro Thr Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 2882 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2882 Cys Ala Lys Asp Ser Gly Gly Asn Asp Tyr Trp 1 5 10 <210> 2883 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2883 cggttcacca tctccagata taattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaagatt cgggggggaa tgactactgg 120 ggccaggga 129 <210> 2884 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2884 Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Asp Ser Gly Gly Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 2885 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2885 cggttcacca tctccagata taattccaag aacacgctgt atctgcaaat caacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaagatt cgggggggaa tgactactgg 120 ggccaggga 129 <210> 2886 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2886 Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Asp Ser Gly Gly Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 2887 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2887 cggttcacca tctccagaga taattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaagatt cgggggggaa tgactactgg 120 ggccaggga 129 <210> 2888 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2888 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Asp Ser Gly Gly Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 2889 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2889 cggttcacca tctccagaga taattccaag aacacgctgt atctgcaaat caacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaagatt cgggggggaa tgactactgg 120 ggccaggga 129 <210> 2890 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2890 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Asp Ser Gly Gly Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 2891 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2891 cggttcacca tctccagaga taattccaac aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaagatt cgggggggaa tgactactgg 120 ggccaggga 129 <210> 2892 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2892 Arg Phe Thr Ile Ser Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Asp Ser Gly Gly Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 2893 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2893 cggttcacca tctccagaca taattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaagatt cgggggggaa tgactactgg 120 ggccaggga 129 <210> 2894 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2894 Arg Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Asp Ser Gly Gly Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 2895 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2895 cggttcacca tctccagaca taattccaag aacacgctgt atctgcaaat caacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaagatt cgggggggaa tgactactgg 120 ggccaggga 129 <210> 2896 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2896 Arg Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Asp Ser Gly Gly Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 2897 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2897 cggttcacca tctccagaca taaatccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaagatt cgggggggaa tgactactgg 120 ggccaggga 129 <210> 2898 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2898 Arg Phe Thr Ile Ser Arg His Lys Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Asp Ser Gly Gly Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 2899 <211> 27 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2899 Cys Ala Lys Glu Gly Gly Val Tyr Cys Ser Gly Gly Ser Cys Tyr Ser 1 5 10 15 Asp Asp Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 2900 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2900 ttgaacagcc tgagagccga ggacacggcc gtatattact gtgcgaaaga ggggggggta 60 tattgtagtg gtggtagctg ctactccgac gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2901 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2901 Leu Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 1 5 10 15 Glu Gly Gly Val Tyr Cys Ser Gly Gly Ser Cys Tyr Ser Asp Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 2902 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2902 ttcaacagcc tcagagccga ggacacggcc gtatattact gtgcgaaaga ggggggtgta 60 tattgtagtg gtggtagctg ctactccgac gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2903 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2903 Phe Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 1 5 10 15 Glu Gly Gly Val Tyr Cys Ser Gly Gly Ser Cys Tyr Ser Asp Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 2904 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2904 atgaaccgcc tgcgagccga ggacacggcc gtatattact gtgcgaaaga ggggggggta 60 tattgtagtg gtggtagctg ctactccgac gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2905 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2905 Met Asn Arg Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 1 5 10 15 Glu Gly Gly Val Tyr Cys Ser Gly Gly Ser Cys Tyr Ser Asp Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 2906 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2906 atgaaccgcc tgagagccga ggacacggcc gtatattact gtgcgaaaga ggggggggta 60 tattgtagtg gtggtagctg ctactccgac gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2907 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2907 atgaacagcc tgcgagccga ggacacggcc gtatattact gtgcgaaaga ggggggggta 60 tattgtagtg gtggtagctg ctactccgac gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2908 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2908 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 1 5 10 15 Glu Gly Gly Val Tyr Cys Ser Gly Gly Ser Cys Tyr Ser Asp Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 2909 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2909 atgaacagcc tgagagccga ggacacggcc gtatattact gtgcgaaaga ggggggtgta 60 tattgtagtg gtggtagctg ctactccgac gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2910 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2910 atgaacagcc tgagagccga ggacacggcc gtatattact gtgcgaaaga ggggggggta 60 tattgtagtg gtggtagctg ctactccgac gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2911 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2911 atcaacaccc tgagcgccga ggacacggcc gtatattact gtgcgaaaga ggggggggta 60 tattgtagtg gtggtagctg ctactccgac gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2912 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2912 Ile Asn Thr Leu Ser Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 1 5 10 15 Glu Gly Gly Val Tyr Cys Ser Gly Gly Ser Cys Tyr Ser Asp Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 2913 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2913 Cys Val Lys Thr Gln Asn Lys Trp Gly Gly Ala Phe Asp Ile Trp 1 5 10 15 <210> 2914 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2914 tccagtcaca acaccaagaa ctccctatat ctgcaaatga acagtctgag acctgaggac 60 acggccttct attactgtgt aaaaacacaa aataagtggg ggggtgcttt tgatatctgg 120 ggcctaggg 129 <210> 2915 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2915 Ser Ser His Asn Thr Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Pro Glu Asp Thr Ala Phe Tyr Tyr Cys Val Lys Thr Gln Asn Lys 20 25 30 Trp Gly Gly Ala Phe Asp Ile Trp Gly Leu Gly 35 40 <210> 2916 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2916 tccagagaca acaccaagaa ctccctatat ctgcaaatga acagtctgag acctgaggac 60 acggccttct attactgtgt aaaaacacaa aataagtggg ggggtgcttt tgatatctgg 120 ggcctaggg 129 <210> 2917 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2917 Ser Arg Asp Asn Thr Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Pro Glu Asp Thr Ala Phe Tyr Tyr Cys Val Lys Thr Gln Asn Lys 20 25 30 Trp Gly Gly Ala Phe Asp Ile Trp Gly Leu Gly 35 40 <210> 2918 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2918 tccagacaca acaccaagaa ctccctatat ctgcaaatga acagtctgag acctgaggac 60 acggccttct attactgtgt aaaaacacaa aataagtggg ggggtgcttt tgatatctgg 120 ggcctaggg 129 <210> 2919 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2919 Ser Arg His Asn Thr Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Pro Glu Asp Thr Ala Phe Tyr Tyr Cys Val Lys Thr Gln Asn Lys 20 25 30 Trp Gly Gly Ala Phe Asp Ile Trp Gly Leu Gly 35 40 <210> 2920 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2920 tccagacaca acaccaagaa ctccctatat ctgcaaatga acaggctgag acctgaggac 60 acggccttct attactgtgt aaaaacacaa aataagtggg ggggtgcttt tgatatctgg 120 ggcctaggg 129 <210> 2921 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2921 Ser Arg His Asn Thr Lys Asn Ser Leu Tyr Leu Gln Met Asn Arg Leu 1 5 10 15 Arg Pro Glu Asp Thr Ala Phe Tyr Tyr Cys Val Lys Thr Gln Asn Lys 20 25 30 Trp Gly Gly Ala Phe Asp Ile Trp Gly Leu Gly 35 40 <210> 2922 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2922 tccacagaca acaccaagaa ctccctatat ctgcaaatga acaggctgag acctgaggac 60 acggccttct attactgtgt aaaaacacaa aataagtggg ggggtgcttt tgatatctgg 120 ggcctaggg 129 <210> 2923 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2923 Ser Thr Asp Asn Thr Lys Asn Ser Leu Tyr Leu Gln Met Asn Arg Leu 1 5 10 15 Arg Pro Glu Asp Thr Ala Phe Tyr Tyr Cys Val Lys Thr Gln Asn Lys 20 25 30 Trp Gly Gly Ala Phe Asp Ile Trp Gly Leu Gly 35 40 <210> 2924 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2924 tccagagaca acgccaagaa ctccctgtat ctgcaaatga acagtctgag agctgaggac 60 acggccttgt attactgtgt aaaaacacaa aataagtggg ggggtgcttt tgatatctgg 120 ggcctaggg 129 <210> 2925 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2925 Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Val Lys Thr Gln Asn Lys 20 25 30 Trp Gly Gly Ala Phe Asp Ile Trp Gly Leu Gly 35 40 <210> 2926 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2926 tccagagaca acaccaagaa ctccctatat ctgcaaatga acagtctgag atctgaggac 60 acggccttct attactgtgt aaaaacacaa aataagtggg ggggtgcttt tgatatctgg 120 ggcctaggg 129 <210> 2927 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2927 Ser Arg Asp Asn Thr Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Phe Tyr Tyr Cys Val Lys Thr Gln Asn Lys 20 25 30 Trp Gly Gly Ala Phe Asp Ile Trp Gly Leu Gly 35 40 <210> 2928 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2928 Cys Thr Arg Gln Asp Tyr Gly Ser Gly Lys Glu Asp Val Trp 1 5 10 <210> 2929 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2929 atctccatat atgattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagacaa gactatggtt cagggaaaga ggacgtctgg 120 ggccaaggg 129 <210> 2930 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2930 Ile Ser Ile Tyr Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Gln Asp Tyr 20 25 30 Gly Ser Gly Lys Glu Asp Val Trp Gly Gln Gly 35 40 <210> 2931 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2931 atctccatag atcattcaaa caacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagacaa gactatggtt cagggaaaga ggacgtctgg 120 ggccaaggg 129 <210> 2932 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2932 Ile Ser Ile Asp His Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Gln Asp Tyr 20 25 30 Gly Ser Gly Lys Glu Asp Val Trp Gly Gln Gly 35 40 <210> 2933 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2933 atctccagat ttgattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagacaa gactatggtt cagggaaaga ggacgtctgg 120 ggccaaggg 129 <210> 2934 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2934 Ile Ser Arg Phe Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Gln Asp Tyr 20 25 30 Gly Ser Gly Lys Glu Asp Val Trp Gly Gln Gly 35 40 <210> 2935 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2935 atctccagag attattcaaa caacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagacaa gactatggtt cagggaaaga ggacgtctgg 120 ggccaaggg 129 <210> 2936 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2936 Ile Ser Arg Asp Tyr Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Gln Asp Tyr 20 25 30 Gly Ser Gly Lys Glu Asp Val Trp Gly Gln Gly 35 40 <210> 2937 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2937 atctccagag atgattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagacaa gactatggtt cagggaaaga ggacgtctgg 120 ggccaaggg 129 <210> 2938 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2938 Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Gln Asp Tyr 20 25 30 Gly Ser Gly Lys Glu Asp Val Trp Gly Gln Gly 35 40 <210> 2939 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2939 atctccagag atcattcaaa caacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagacaa gactatggtt cagggaaaga ggacgtctgg 120 ggccaaggg 129 <210> 2940 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2940 Ile Ser Arg Asp His Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Gln Asp Tyr 20 25 30 Gly Ser Gly Lys Glu Asp Val Trp Gly Gln Gly 35 40 <210> 2941 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2941 atctccagac atcattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagacaa gactatggtt cagggaaaga ggacgtctgg 120 ggccaaggg 129 <210> 2942 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2942 Ile Ser Arg His His Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Gln Asp Tyr 20 25 30 Gly Ser Gly Lys Glu Asp Val Trp Gly Gln Gly 35 40 <210> 2943 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2943 Cys Thr Leu Ser Trp Asp Tyr Gly Ser Gly Ser Val Trp 1 5 10 <210> 2944 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2944 accatctcca tagattattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactctc tcctgggact atggttcggg gagtgtctgg 120 ggccaaggg 129 <210> 2945 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2945 Thr Ile Ser Ile Asp Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Leu Ser Trp 20 25 30 Asp Tyr Gly Ser Gly Ser Val Trp Gly Gln Gly 35 40 <210> 2946 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2946 accatctcca gagattattc aaagaacacg gcgtatctgc aaatgaacag ccttaaaacc 60 gaggacacgg ccgtgtatta ctgtactctc tcctgggact atggttcggg gagtgtctgg 120 ggccaaggg 129 <210> 2947 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2947 Thr Ile Ser Arg Asp Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Leu Ser Trp 20 25 30 Asp Tyr Gly Ser Gly Ser Val Trp Gly Gln Gly 35 40 <210> 2948 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2948 accatctcca gagatgattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactctc tcctgggact atggttcggg gagtgtctgg 120 ggccaaggg 129 <210> 2949 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2949 Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Leu Ser Trp 20 25 30 Asp Tyr Gly Ser Gly Ser Val Trp Gly Gln Gly 35 40 <210> 2950 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2950 accatctcca gacattattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactctc tcctgggact atggttcggg gagtgtctgg 120 ggccaaggg 129 <210> 2951 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2951 Thr Ile Ser Arg His Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Leu Ser Trp 20 25 30 Asp Tyr Gly Ser Gly Ser Val Trp Gly Gln Gly 35 40 <210> 2952 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2952 accatctcca gacatcattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactctc tcctgggact atggttcggg gagtgtctgg 120 ggccaaggg 129 <210> 2953 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2953 Thr Ile Ser Arg His His Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Leu Ser Trp 20 25 30 Asp Tyr Gly Ser Gly Ser Val Trp Gly Gln Gly 35 40 <210> 2954 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2954 aacatctcca tagatgattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactctc tcctgggact atggttcggg gagtgtctgg 120 ggccaaggg 129 <210> 2955 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2955 Asn Ile Ser Ile Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Leu Ser Trp 20 25 30 Asp Tyr Gly Ser Gly Ser Val Trp Gly Gln Gly 35 40 <210> 2956 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2956 aacatctcca gagatcattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactctc tcctgggact atggttcggg gagtgtctgg 120 ggccaaggg 129 <210> 2957 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2957 Asn Ile Ser Arg Asp His Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Leu Ser Trp 20 25 30 Asp Tyr Gly Ser Gly Ser Val Trp Gly Gln Gly 35 40 <210> 2958 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2958 Cys Thr Ser Thr Trp Gly Gly Tyr Tyr Gly Met Asp Val Trp 1 5 10 <210> 2959 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2959 ttctccagag attattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagtacg tggggaggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2960 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2960 Phe Ser Arg Asp Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Thr Trp Gly 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 2961 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2961 ttctccagag atcattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagtacg tggggaggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2962 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2962 Phe Ser Arg Asp His Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Thr Trp Gly 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 2963 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2963 atctccatag atgattcaaa caacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagtacg tggggaggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2964 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2964 Ile Ser Ile Asp Asp Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Thr Trp Gly 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 2965 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2965 atctccatag atcattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagtacg tggggaggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2966 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2966 Ile Ser Ile Asp His Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Thr Trp Gly 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 2967 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2967 atctccagag atgattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagtacg tggggaggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2968 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2968 Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Thr Trp Gly 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 2969 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2969 atctccagag atcattcaaa caacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagtacg tggggaggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2970 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2970 Ile Ser Arg Asp His Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Thr Trp Gly 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 2971 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2971 atctccagac atcattcaaa gaacacggcg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacggccg tgtattactg tactagtacg tggggaggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 2972 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2972 Ile Ser Arg His His Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Thr Trp Gly 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 2973 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2973 Cys Ala Lys Val Glu Ala Pro Tyr Tyr Phe Asp Tyr Trp 1 5 10 <210> 2974 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2974 accatctcca tatataattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gtcgaggccc cgtactactt tgactactgg 120 ggccaggga 129 <210> 2975 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2975 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Glu 20 25 30 Ala Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2976 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2976 accatctcca tagataattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gtcgaggccc cgtactactt tgactactgg 120 ggccaggga 129 <210> 2977 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2977 Thr Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Glu 20 25 30 Ala Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2978 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2978 accatctcca tacataattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gtcgaggccc cgtactactt tgactactgg 120 ggccaggga 129 <210> 2979 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2979 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Glu 20 25 30 Ala Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2980 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2980 accatctcca gatataattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gtcgaggccc cgtactactt tgactactgg 120 ggccaggga 129 <210> 2981 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2981 Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Glu 20 25 30 Ala Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2982 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2982 accatctcca gagataattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gtcgaggccc cgtactactt tgactactgg 120 ggccaggga 129 <210> 2983 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2983 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Glu 20 25 30 Ala Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2984 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2984 aacatctcca tatataattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gtcgaggccc cgtactactt tgactactgg 120 ggccaggga 129 <210> 2985 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2985 Asn Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Glu 20 25 30 Ala Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2986 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2986 aacatctcca tagataattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gtcgaggccc cgtactactt tgactactgg 120 ggccaggga 129 <210> 2987 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2987 Asn Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Glu 20 25 30 Ala Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 2988 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2988 Cys Gly Arg Gly Gly Leu Tyr Gly Leu Asn Tyr Trp 1 5 10 <210> 2989 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2989 atcaccatga ccacagacac atccacgacc acagcctaca tggatgtgag gagcctgaga 60 tctgacgaca cggccgtata ttactgtggg agaggcggac tttacggttt gaactactgg 120 ggccaggga 129 <210> 2990 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2990 Ile Thr Met Thr Thr Asp Thr Ser Thr Thr Thr Ala Tyr Met Asp Val 1 5 10 15 Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Gly Arg Gly 20 25 30 Gly Leu Tyr Gly Leu Asn Tyr Trp Gly Gln Gly 35 40 <210> 2991 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2991 atcaccatga ccacacacac atccacgacc acagcctaca tggatgtgag gagcctgaga 60 tctgacgaca cggccgtata ttactgtggg agaggcggac tttacggttt gaactactgg 120 ggccaggga 129 <210> 2992 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2992 Ile Thr Met Thr Thr His Thr Ser Thr Thr Thr Ala Tyr Met Asp Val 1 5 10 15 Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Gly Arg Gly 20 25 30 Gly Leu Tyr Gly Leu Asn Tyr Trp Gly Gln Gly 35 40 <210> 2993 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2993 atcaccatga ccacacacac acccacgacc acagcctaca tggatgtgag gagcctgaga 60 tctgacgaca cggccgtata ttactgtggg agaggcggac tttacggttt gaactactgg 120 ggccaggga 129 <210> 2994 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2994 Ile Thr Met Thr Thr His Thr Pro Thr Thr Thr Ala Tyr Met Asp Val 1 5 10 15 Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Gly Arg Gly 20 25 30 Gly Leu Tyr Gly Leu Asn Tyr Trp Gly Gln Gly 35 40 <210> 2995 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2995 atcaccatga ccacacacac aaccacgacc acagcctaca tggatgtgag gagcctgaga 60 tctgacgaca cggccgtata ttactgtggg agaggcggac tttacggttt gaactactgg 120 ggccaggga 129 <210> 2996 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2996 Ile Thr Met Thr Thr His Thr Thr Thr Thr Thr Ala Tyr Met Asp Val 1 5 10 15 Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Gly Arg Gly 20 25 30 Gly Leu Tyr Gly Leu Asn Tyr Trp Gly Gln Gly 35 40 <210> 2997 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2997 atcaccatca ccacagacac atccacgacc acagcctaca tggatgtgag gagcctgaga 60 tctgacgaca cggccgtata ttactgtggg agaggcggac tttacggttt gaactactgg 120 ggccaggga 129 <210> 2998 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2998 Ile Thr Ile Thr Thr Asp Thr Ser Thr Thr Thr Ala Tyr Met Asp Val 1 5 10 15 Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Gly Arg Gly 20 25 30 Gly Leu Tyr Gly Leu Asn Tyr Trp Gly Gln Gly 35 40 <210> 2999 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 2999 atcaccatca ccacacacac atccacgacc acagcctaca tggatgtgag gagcctgaga 60 tctgacgaca cggccgtata ttactgtggg agaggcggac tttacggttt gaactactgg 120 ggccaggga 129 <210> 3000 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3000 Ile Thr Ile Thr Thr His Thr Ser Thr Thr Thr Ala Tyr Met Asp Val 1 5 10 15 Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Gly Arg Gly 20 25 30 Gly Leu Tyr Gly Leu Asn Tyr Trp Gly Gln Gly 35 40 <210> 3001 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3001 atcaccatca ccacacacac aaccacgacc acagcctaca tggatgtgag gagcctgaga 60 tctgacgaca cggccgtata ttactgtggg agaggcggac tttacggttt gaactactgg 120 ggccaggga 129 <210> 3002 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3002 Ile Thr Ile Thr Thr His Thr Thr Thr Thr Thr Ala Tyr Met Asp Val 1 5 10 15 Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Gly Arg Gly 20 25 30 Gly Leu Tyr Gly Leu Asn Tyr Trp Gly Gln Gly 35 40 <210> 3003 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3003 Cys Ala Lys Asn Lys Gly Gly Leu Pro Gly Asn Trp 1 5 10 <210> 3004 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3004 ttcaccatct ccagatacaa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaaacaaag gtggactccc aggcaactgg 120 ggccaggga 129 <210> 3005 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3005 Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asn 20 25 30 Lys Gly Gly Leu Pro Gly Asn Trp Gly Gln Gly 35 40 <210> 3006 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3006 ttcaccatct ccagagacaa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaaacaaag gtggactccc aggcaactgg 120 ggccaggga 129 <210> 3007 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3007 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asn 20 25 30 Lys Gly Gly Leu Pro Gly Asn Trp Gly Gln Gly 35 40 <210> 3008 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3008 ttcaccatct ccagagacaa ttccaagaac acgctgtatc tgaaaatcaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaaacaaag gtggactccc aggcaactgg 120 ggccaggga 129 <210> 3009 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3009 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Lys Ile 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asn 20 25 30 Lys Gly Gly Leu Pro Gly Asn Trp Gly Gln Gly 35 40 <210> 3010 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3010 ttcaccatct ccagacacaa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaaacaaag gtggactccc aggcaactgg 120 ggccaggga 129 <210> 3011 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3011 Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asn 20 25 30 Lys Gly Gly Leu Pro Gly Asn Trp Gly Gln Gly 35 40 <210> 3012 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3012 ttcaccatct ccagacacaa ttccaagaac acgctgtatc tgcaaatcaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaaacaaag gtggactccc aggcaactgg 120 ggccaggga 129 <210> 3013 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3013 Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asn 20 25 30 Lys Gly Gly Leu Pro Gly Asn Trp Gly Gln Gly 35 40 <210> 3014 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3014 ttcaccatct ccagacacaa taccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaaacaaag gtggactccc aggcaactgg 120 ggccaggga 129 <210> 3015 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3015 Phe Thr Ile Ser Arg His Asn Thr Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asn 20 25 30 Lys Gly Gly Leu Pro Gly Asn Trp Gly Gln Gly 35 40 <210> 3016 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3016 ttcaccatct ccacacacaa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaaacaaag gtggactccc aggcaactgg 120 ggccaggga 129 <210> 3017 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3017 Phe Thr Ile Ser Thr His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asn 20 25 30 Lys Gly Gly Leu Pro Gly Asn Trp Gly Gln Gly 35 40 <210> 3018 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3018 Cys Ala Ser Arg Gly Gly Asp Pro Tyr Tyr Phe Asp Tyr Trp 1 5 10 <210> 3019 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3019 ttctccagag ataattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgagtagg ggtggggacc cctactactt tgactactgg 120 ggccaggga 129 <210> 3020 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3020 Phe Ser Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Arg Gly Gly 20 25 30 Asp Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3021 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3021 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgagtagg ggtggggacc cctactactt tgactactgg 120 ggccaggga 129 <210> 3022 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3022 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Arg Gly Gly 20 25 30 Asp Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3023 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3023 atctccatag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgagtagg ggtggggacc cctactactt tgactactgg 120 ggccaggga 129 <210> 3024 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3024 Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Arg Gly Gly 20 25 30 Asp Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3025 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3025 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgagtagg ggtggggacc cctactactt tgactactgg 120 ggccaggga 129 <210> 3026 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3026 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Arg Gly Gly 20 25 30 Asp Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3027 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3027 atctccagat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgagtagg ggtggggacc cctactactt tgactactgg 120 ggccaggga 129 <210> 3028 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3028 Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Arg Gly Gly 20 25 30 Asp Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3029 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3029 atctccagat ataattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgagtagg ggtggggacc cctactactt tgactactgg 120 ggccaggga 129 <210> 3030 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3030 Ile Ser Arg Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Arg Gly Gly 20 25 30 Asp Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3031 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3031 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgagtagg ggtggggacc cctactactt tgactactgg 120 ggccaggga 129 <210> 3032 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3032 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Arg Gly Gly 20 25 30 Asp Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3033 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3033 Cys Ala Arg Asp Ile Ala Ala Ala Gly Gly Val Val Arg Asp Tyr Trp 1 5 10 15 <210> 3034 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3034 tgggacacgt ccacgagcac tgtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag ggatatagca gcagctggtg gggtggtgag ggactactgg 120 ggccaggga 129 <210> 3035 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3035 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ile Ala Ala Ala 20 25 30 Gly Gly Val Val Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 3036 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3036 tgggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag ggatatagca gcagctggtg gggtggtgag ggactactgg 120 ggccaggga 129 <210> 3037 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3037 tgggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag ggatatagca gcagctgggg gggtggtgag ggactactgg 120 ggccaggga 129 <210> 3038 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3038 tgggacacgt ccacgagcac agtctacatg gagctgagca gcctgagagc tgaggacacg 60 gccgtgtatt actgtgcgag ggatatagca gcagctggtg gggtggtgag ggactactgg 120 ggccaggga 129 <210> 3039 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3039 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ile Ala Ala Ala 20 25 30 Gly Gly Val Val Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 3040 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3040 tgggacacgc ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag ggatatagca gcagctggtg gggtggtgag ggactactgg 120 ggccaggga 129 <210> 3041 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3041 Trp Asp Thr Pro Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ile Ala Ala Ala 20 25 30 Gly Gly Val Val Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 3042 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3042 agggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag ggatatagca gcagctggtg gggtggtgag ggactactgg 120 ggccaggga 129 <210> 3043 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3043 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ile Ala Ala Ala 20 25 30 Gly Gly Val Val Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 3044 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3044 Cys Gly Gly Ser Tyr Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 1 5 10 <210> 3045 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3045 ttctccagag ataattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tggggggtca tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3046 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3046 Phe Ser Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Gly Ser Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3047 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3047 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tggggggtca tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3048 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3048 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Gly Ser Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3049 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3049 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tggggggtca tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3050 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3050 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Gly Ser Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3051 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3051 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tggggggtca tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3052 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3052 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Gly Ser Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3053 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3053 atctccagac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tggggggtca tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3054 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3054 Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Gly Ser Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3055 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3055 atctccagac ataattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tggggggtca tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3056 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3056 Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Gly Ser Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3057 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3057 Cys Ala Lys Asp Ile Ala Thr Asp Ile Val Ala Thr Glu Glu Asp Tyr 1 5 10 15 Ala Tyr Ala Leu Asp Val Trp 20 <210> 3058 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3058 ctttatttgc agatgcgcag tctgcgagct gaggacacgg ccctgtattt ctgtgcaaaa 60 gatatcgcca ctgacatagt ggcgacggag gaagactacg cctacgctct agacgtctgg 120 ggccaaggg 129 <210> 3059 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3059 Leu Tyr Leu Gln Met Arg Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr 1 5 10 15 Phe Cys Ala Lys Asp Ile Ala Thr Asp Ile Val Ala Thr Glu Glu Asp 20 25 30 Tyr Ala Tyr Ala Leu Asp Val Trp Gly Gln Gly 35 40 <210> 3060 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3060 ctgtatttgc tgatgagcag gctgcgagct gaggacacgg ccctgtattt ctgtgcaaaa 60 gatatcgcca ctgacatagt ggcgacggag gaagactacg cctacgctct agacgtctgg 120 ggccaaggg 129 <210> 3061 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3061 Leu Tyr Leu Leu Met Ser Arg Leu Arg Ala Glu Asp Thr Ala Leu Tyr 1 5 10 15 Phe Cys Ala Lys Asp Ile Ala Thr Asp Ile Val Ala Thr Glu Glu Asp 20 25 30 Tyr Ala Tyr Ala Leu Asp Val Trp Gly Gln Gly 35 40 <210> 3062 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3062 ctgtatttgc agatgagcag tctgcgagct gaggacacgg ccctgtattt ctgtgcaaaa 60 gatatcgcca ctgacatagt ggcgacggag gaagactacg cctacgctct agacgtctgg 120 ggccaaggg 129 <210> 3063 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3063 Leu Tyr Leu Gln Met Ser Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr 1 5 10 15 Phe Cys Ala Lys Asp Ile Ala Thr Asp Ile Val Ala Thr Glu Glu Asp 20 25 30 Tyr Ala Tyr Ala Leu Asp Val Trp Gly Gln Gly 35 40 <210> 3064 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3064 ctgtatttgc agatccgcag tctgcgagct gaggacacgg ccctgtattt ctgtgcaaaa 60 gatatcgcca ctgacatagt ggcgacggag gaagactacg cctacgctct agacgtctgg 120 ggccaaggg 129 <210> 3065 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3065 Leu Tyr Leu Gln Ile Arg Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr 1 5 10 15 Phe Cys Ala Lys Asp Ile Ala Thr Asp Ile Val Ala Thr Glu Glu Asp 20 25 30 Tyr Ala Tyr Ala Leu Asp Val Trp Gly Gln Gly 35 40 <210> 3066 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3066 atgtatttgc tgatgagcag tctgcgagct gaggacacgg ccctgtattt ctgtgcaaaa 60 gatatcgcca ctgacatagt ggcgacggag gaagactacg cctacgctct agacgtctgg 120 ggccaaggg 129 <210> 3067 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3067 Met Tyr Leu Leu Met Ser Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr 1 5 10 15 Phe Cys Ala Lys Asp Ile Ala Thr Asp Ile Val Ala Thr Glu Glu Asp 20 25 30 Tyr Ala Tyr Ala Leu Asp Val Trp Gly Gln Gly 35 40 <210> 3068 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3068 atgtatttgc agatgtgcag tctgcgagct gaggacacgg ccctgtattt ctgtgcaaaa 60 gatatcgcca ctgacatagt ggcgacggag gaagactacg cctacgctct agacgtctgg 120 ggccaaggg 129 <210> 3069 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3069 Met Tyr Leu Gln Met Cys Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr 1 5 10 15 Phe Cys Ala Lys Asp Ile Ala Thr Asp Ile Val Ala Thr Glu Glu Asp 20 25 30 Tyr Ala Tyr Ala Leu Asp Val Trp Gly Gln Gly 35 40 <210> 3070 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3070 Cys Ala Lys Asp Leu Gly Ser Tyr Gly Arg Phe Asp Tyr Trp 1 5 10 <210> 3071 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3071 ttctccagag acaattccaa taatacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat cttggcagct atggccgctt tgactactgg 120 ggccaggga 129 <210> 3072 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3072 Phe Ser Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Gly 20 25 30 Ser Tyr Gly Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3073 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3073 ttctccagac acaattccaa gaatacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat cttggcagct atggccgctt tgactactgg 120 ggccaggga 129 <210> 3074 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3074 Phe Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Gly 20 25 30 Ser Tyr Gly Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3075 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3075 atctccatat acaattccaa gaatacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat cttggcagct atggccgctt tgactactgg 120 ggccaggga 129 <210> 3076 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3076 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Gly 20 25 30 Ser Tyr Gly Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3077 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3077 atctccatac acaattccaa gaatacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat cttggcagct atggccgctt tgactactgg 120 ggccaggga 129 <210> 3078 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3078 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Gly 20 25 30 Ser Tyr Gly Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3079 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3079 atctccagag acaattccaa gaatacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat cttggcagct atggccgctt tgactactgg 120 ggccaggga 129 <210> 3080 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3080 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Gly 20 25 30 Ser Tyr Gly Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3081 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3081 atctccagag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat cttggcagct atggccgctt tgactactgg 120 ggccaggga 129 <210> 3082 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3082 Cys Ala Lys Asp His Gly Glu Ser Tyr Pro Trp Tyr Ser Arg Gly Gly 1 5 10 15 Gly Met Asp Val Trp 20 <210> 3083 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3083 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatc atggcgaatc ttatccttgg tatagcaggg gagggggtat ggacgtctgg 120 ggccaaggg 129 <210> 3084 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3084 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp His Gly Glu Ser Tyr Pro Trp Tyr Ser 20 25 30 Arg Gly Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3085 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3085 aacacgctgt atctgcaaat caacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatc atggcgaatc ttatccttgg tatagcaggg gagggggtat ggacgtctgg 120 ggccaaggg 129 <210> 3086 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3086 Asn Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp His Gly Glu Ser Tyr Pro Trp Tyr Ser 20 25 30 Arg Gly Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3087 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3087 aacacgatgt atctgcaaat caacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatc atggcgaatc ttatccttgg tatagcaggg gagggggtat ggacgtctgg 120 ggccaaggg 129 <210> 3088 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3088 Asn Thr Met Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp His Gly Glu Ser Tyr Pro Trp Tyr Ser 20 25 30 Arg Gly Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3089 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3089 aacacgatgt atctccaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatc atggcgaatc ttatccttgg tatagcaggg gagggggtat ggacgtctgg 120 ggccaaggg 129 <210> 3090 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3090 Asn Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp His Gly Glu Ser Tyr Pro Trp Tyr Ser 20 25 30 Arg Gly Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3091 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3091 Cys Ala Arg Gly Val Asp Leu Glu Pro Asp Tyr Trp 1 5 10 <210> 3092 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3092 ttcacggtct acagacacga ctcgaggaat atggtatttc ttcagatgaa cagactgaga 60 gccgaggaca cggccgtgta tttctgtgcg aggggcgtcg acctagagcc tgactactgg 120 ggccaggga 129 <210> 3093 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3093 Phe Thr Val Tyr Arg His Asp Ser Arg Asn Met Val Phe Leu Gln Met 1 5 10 15 Asn Arg Leu Arg Ala Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Gly 20 25 30 Val Asp Leu Glu Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 3094 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3094 ttcaccgtct accgacacga ctcgaggaat atggtatttc ttcagatgaa cagactgaga 60 gccgaggaca cggccgtgta tttctgtgcg aggggcgtcg acctagagcc tgactactgg 120 ggccaggga 129 <210> 3095 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3095 ttcaccgtct acagccacga ctcgaggaat atggtatttc ttcagatgaa cagactgaga 60 gccgaggaca cggccgtgta tttctgtgcg aggggcgtcg acctagagcc tgactactgg 120 ggccaggga 129 <210> 3096 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3096 Phe Thr Val Tyr Ser His Asp Ser Arg Asn Met Val Phe Leu Gln Met 1 5 10 15 Asn Arg Leu Arg Ala Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Gly 20 25 30 Val Asp Leu Glu Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 3097 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3097 ttcaccgtct acagagacga ctcgaggaat atggtatttc ttcagatgaa cagactgaga 60 gccgaggaca cggccgtgta tttctgtgcg aggggcgtcg acctagagcc tgactactgg 120 ggccaggga 129 <210> 3098 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3098 Phe Thr Val Tyr Arg Asp Asp Ser Arg Asn Met Val Phe Leu Gln Met 1 5 10 15 Asn Arg Leu Arg Ala Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Gly 20 25 30 Val Asp Leu Glu Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 3099 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3099 ttcaccgtct acagacacga ctcgaggaat atggtatttc ttcagatgaa cagactgaga 60 gccgaggaca cggccgtgta tttctgtgcg aggggcgtcg acctagagcc tgactactgg 120 ggccaggga 129 <210> 3100 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3100 tccacggtct accgacacga ctcgagtaat atggtatttc ttcagatgaa cagactgaga 60 gccgaggaca cggccgtgta tttctgtgcg aggggcgtcg acctagagcc tgactactgg 120 ggccaggga 129 <210> 3101 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3101 Ser Thr Val Tyr Arg His Asp Ser Ser Asn Met Val Phe Leu Gln Met 1 5 10 15 Asn Arg Leu Arg Ala Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Gly 20 25 30 Val Asp Leu Glu Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 3102 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3102 Cys Thr Arg His Arg Val Gln Gln Pro Phe Asp Pro Trp 1 5 10 <210> 3103 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3103 accatctcca tatatgattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga catagggtgc agcagccttt cgacccctgg 120 ggccaggga 129 <210> 3104 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3104 Thr Ile Ser Ile Tyr Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg His Arg 20 25 30 Val Gln Gln Pro Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3105 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3105 accatctcca tagattattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga catagggtgc agcagccttt cgacccctgg 120 ggccaggga 129 <210> 3106 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3106 Thr Ile Ser Ile Asp Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg His Arg 20 25 30 Val Gln Gln Pro Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3107 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3107 accatctcca tagatgattc aaacaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga catagggtgc agcagccttt cgacccctgg 120 ggccaggga 129 <210> 3108 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3108 Thr Ile Ser Ile Asp Asp Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg His Arg 20 25 30 Val Gln Gln Pro Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3109 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3109 accatctcca gagattattc aaagaacacg gcgtatctgc aaatgaacag ccttaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga catagggtgc agcagccttt cgacccctgg 120 ggccaggga 129 <210> 3110 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3110 Thr Ile Ser Arg Asp Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg His Arg 20 25 30 Val Gln Gln Pro Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3111 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3111 accatctcca gagatgattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga catagggtgc agcagccttt cgacccctgg 120 ggccaggga 129 <210> 3112 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3112 Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg His Arg 20 25 30 Val Gln Gln Pro Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3113 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3113 aacatctcca tagatgattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactaga catagggtgc agcagccttt cgacccctgg 120 ggccaggga 129 <210> 3114 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3114 Asn Ile Ser Ile Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg His Arg 20 25 30 Val Gln Gln Pro Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3115 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3115 Cys Ala Lys Val Gly Pro Gly Trp Tyr Arg Val Asp Tyr Trp 1 5 10 <210> 3116 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3116 ttctccagac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagtg ggcccaggct ggtacagagt tgactactgg 120 ggccaggga 129 <210> 3117 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3117 Phe Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Pro 20 25 30 Gly Trp Tyr Arg Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 3118 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3118 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagtg ggcccaggct ggtacagagt tgactactgg 120 ggccaggga 129 <210> 3119 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3119 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Pro 20 25 30 Gly Trp Tyr Arg Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 3120 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3120 atctccatag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagtg ggcccaggct ggtacagagt tgactactgg 120 ggccaggga 129 <210> 3121 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3121 Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Pro 20 25 30 Gly Trp Tyr Arg Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 3122 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3122 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagtg ggcccaggct ggtacagagt tgactactgg 120 ggccaggga 129 <210> 3123 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3123 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Pro 20 25 30 Gly Trp Tyr Arg Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 3124 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3124 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagtg ggcccaggct ggtacagagt tgactactgg 120 ggccaggga 129 <210> 3125 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3125 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Pro 20 25 30 Gly Trp Tyr Arg Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 3126 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3126 atctccagac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagtg ggcccaggct ggtacagagt tgactactgg 120 ggccaggga 129 <210> 3127 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3127 Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Pro 20 25 30 Gly Trp Tyr Arg Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 3128 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3128 Cys Ala Arg Asp Gly Phe Asn Ser Gly Ser Ala Trp 1 5 10 <210> 3129 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3129 ttcaccgtct ccagagacaa cgccaagaac acgctgtatc tccaaatgaa cagtctgaga 60 gtcgaagaca cggctgtgta ttactgtgca agagatggat ttaattcggg gagtgcctgg 120 ggccaggga 129 <210> 3130 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3130 Phe Thr Val Ser Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Val Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Gly Phe Asn Ser Gly Ser Ala Trp Gly Gln Gly 35 40 <210> 3131 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3131 ttcaccgtct ccagagacaa cgccaagaac acgctgtatc tccaaatcaa cagtctgaga 60 gtcgaagaca cggctgtgta ttactgtgca agagatggat ttaattcggg gagtgcctgg 120 ggccaggga 129 <210> 3132 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3132 Phe Thr Val Ser Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Ile 1 5 10 15 Asn Ser Leu Arg Val Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Gly Phe Asn Ser Gly Ser Ala Trp Gly Gln Gly 35 40 <210> 3133 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3133 ttcaccgtct ccagagacaa cgccaacaac acgctgtatc tccaaatgaa cagtctgaga 60 gtcgaagaca cggctgtgta ttactgtgca agagatggat ttaattcggg gagtgcctgg 120 ggccaggga 129 <210> 3134 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3134 Phe Thr Val Ser Arg Asp Asn Ala Asn Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Val Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Gly Phe Asn Ser Gly Ser Ala Trp Gly Gln Gly 35 40 <210> 3135 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3135 ttcaccgtct ccagacacaa cgccaagaac acgctgtatc tccaaatgaa cagtctgaga 60 gtcgaagaca cggctgtgta ttactgtgca agagatggat ttaattcggg gagtgcctgg 120 ggccaggga 129 <210> 3136 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3136 Phe Thr Val Ser Arg His Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Val Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Gly Phe Asn Ser Gly Ser Ala Trp Gly Gln Gly 35 40 <210> 3137 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3137 ttcaccgtct ccagacacaa cgccaagaac acgctgtatc tccaaatgaa cagtctgaga 60 gtcgaacaca cggctgtgta ttactgtgca agagatggat ttaattcggg gagtgcctgg 120 ggccaggga 129 <210> 3138 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3138 Phe Thr Val Ser Arg His Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Val Glu His Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Gly Phe Asn Ser Gly Ser Ala Trp Gly Gln Gly 35 40 <210> 3139 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3139 ttcaccgtct ccagacacaa cgccaagaac acgctgtatc tccaaatcaa cagtctgaga 60 gtcgaagaca cggctgtgta ttactgtgca agagatggat ttaattcggg gagtgcctgg 120 ggccaggga 129 <210> 3140 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3140 Phe Thr Val Ser Arg His Asn Ala Lys Asn Thr Leu Tyr Leu Gln Ile 1 5 10 15 Asn Ser Leu Arg Val Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Gly Phe Asn Ser Gly Ser Ala Trp Gly Gln Gly 35 40 <210> 3141 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3141 Cys Ala Lys Ser Ala Asp Glu Trp Glu Asn Asp Tyr Trp 1 5 10 <210> 3142 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3142 accatctcca tagacaattc caacaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa agcgcagacg agtgggaaaa tgactactgg 120 ggccaggga 129 <210> 3143 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3143 Thr Ile Ser Ile Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ser Ala 20 25 30 Asp Glu Trp Glu Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 3144 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3144 accatctcca tacacaattc caacaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa agcgcagacg agtgggaaaa tgactactgg 120 ggccaggga 129 <210> 3145 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3145 Thr Ile Ser Ile His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ser Ala 20 25 30 Asp Glu Trp Glu Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 3146 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3146 accatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa agcgcagacg agtgggaaaa tgactactgg 120 ggccaggga 129 <210> 3147 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3147 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ser Ala 20 25 30 Asp Glu Trp Glu Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 3148 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3148 accatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa agcgcagacg aatgggaaaa tgactactgg 120 ggccaggga 129 <210> 3149 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3149 accatctcca gacacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa agcgcagacg agtgggaaaa tgactactgg 120 ggccaggga 129 <210> 3150 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3150 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ser Ala 20 25 30 Asp Glu Trp Glu Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 3151 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3151 aacatctcca tagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa agcgcagacg agtgggaaaa tgactactgg 120 ggccaggga 129 <210> 3152 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3152 Asn Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ser Ala 20 25 30 Asp Glu Trp Glu Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 3153 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3153 Cys Ala Lys Asp Pro Val Ser Thr Trp Gly Gly Asp Trp Phe Asp Pro 1 5 10 15 Trp <210> 3154 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3154 gacaattcca agaacacgct gtatctgcaa atgaaccgcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga tcctgtatct acttgggggg gggactggtt cgacccctgg 120 ggccaggga 129 <210> 3155 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3155 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Arg Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Val Ser Thr Trp 20 25 30 Gly Gly Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3156 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3156 gacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga tcctgtatct acttgggggg gggactggtt cgacccctgg 120 ggccaggga 129 <210> 3157 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3157 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Val Ser Thr Trp 20 25 30 Gly Gly Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3158 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3158 gacaattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga tcctgtatct acttgggggg gggactggtt cgacccctgg 120 ggccaggga 129 <210> 3159 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3159 Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Val Ser Thr Trp 20 25 30 Gly Gly Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3160 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3160 gacaatccca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga tcctgtatct acttgggggg gggactggtt cgacccctgg 120 ggccaggga 129 <210> 3161 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3161 Asp Asn Pro Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Val Ser Thr Trp 20 25 30 Gly Gly Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3162 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3162 cacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga tcctgtatct acttgggggg gggactggtt cgacccctgg 120 ggccaggga 129 <210> 3163 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3163 His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Val Ser Thr Trp 20 25 30 Gly Gly Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3164 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3164 cacaattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga tcctgtatct acttgggggg gggactggtt cgacccctgg 120 ggccaggga 129 <210> 3165 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3165 His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Val Ser Thr Trp 20 25 30 Gly Gly Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3166 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3166 Cys Ala Lys Asp Gly Ala Trp Thr Tyr Tyr Tyr Asp Ser Ser Gly Ser 1 5 10 15 Arg Gly Gly Tyr Trp 20 <210> 3167 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3167 tacacgatgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatg gggcgtggac gtattactat gatagtagtg gttcccgggg gggctactgg 120 ggccaggga 129 <210> 3168 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3168 Tyr Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Gly Ala Trp Thr Tyr Tyr Tyr Asp Ser 20 25 30 Ser Gly Ser Arg Gly Gly Tyr Trp Gly Gln Gly 35 40 <210> 3169 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3169 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatg gggcgtggac gtattactat gatagtagtg gttcccgggg gggctactgg 120 ggccaggga 129 <210> 3170 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3170 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Gly Ala Trp Thr Tyr Tyr Tyr Asp Ser 20 25 30 Ser Gly Ser Arg Gly Gly Tyr Trp Gly Gln Gly 35 40 <210> 3171 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3171 aacacgatgt atctgcaaat caacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatg gggcgtggac gtattactat gatagtagtg gttcccgggg gggctactgg 120 ggccaggga 129 <210> 3172 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3172 Asn Thr Met Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Gly Ala Trp Thr Tyr Tyr Tyr Asp Ser 20 25 30 Ser Gly Ser Arg Gly Gly Tyr Trp Gly Gln Gly 35 40 <210> 3173 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3173 tacacgctgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatg gggcgtggac gtattactat gatagtagtg gttcccgggg gggctactgg 120 ggccaggga 129 <210> 3174 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3174 Tyr Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Gly Ala Trp Thr Tyr Tyr Tyr Asp Ser 20 25 30 Ser Gly Ser Arg Gly Gly Tyr Trp Gly Gln Gly 35 40 <210> 3175 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3175 aacacgctgt atctgcaaat caacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatg gggcgtggac gtattactat gatagtagtg gttcccgggg gggctactgg 120 ggccaggga 129 <210> 3176 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3176 Asn Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Gly Ala Trp Thr Tyr Tyr Tyr Asp Ser 20 25 30 Ser Gly Ser Arg Gly Gly Tyr Trp Gly Gln Gly 35 40 <210> 3177 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3177 aacacgatgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatg gggcgtggac gtattactat gatagtagtg gttcccgggg gggctactgg 120 ggccaggga 129 <210> 3178 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3178 Asn Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Gly Ala Trp Thr Tyr Tyr Tyr Asp Ser 20 25 30 Ser Gly Ser Arg Gly Gly Tyr Trp Gly Gln Gly 35 40 <210> 3179 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3179 Cys Ala Lys Gly Arg Gly Asp Asn Ser Trp Tyr Asp Tyr Trp 1 5 10 <210> 3180 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3180 ttctccagag ataattccaa gagcacgctg tatctgcaaa tgaacagcct gagagccgaa 60 gacacggccg tatattactg tgctaaagga aggggggaca acagctggta cgactactgg 120 ggccaggga 129 <210> 3181 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3181 Phe Ser Arg Asp Asn Ser Lys Ser Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg Gly 20 25 30 Asp Asn Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3182 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3182 atctccatat ataattccaa gagcacgctg tatctgcaaa tgaacagcct gagagccgaa 60 gacacggccg tatattactg tgctaaagga aggggggaca acagctggta cgactactgg 120 ggccaggga 129 <210> 3183 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3183 Ile Ser Ile Tyr Asn Ser Lys Ser Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg Gly 20 25 30 Asp Asn Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3184 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3184 atctccatag ataattccaa gagcacgctg tatctgcaaa tgaacagcct gagagccgaa 60 gacacggccg tatattactg tgctaaagga aggggggaca acagctggta cgactactgg 120 ggccaggga 129 <210> 3185 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3185 Ile Ser Ile Asp Asn Ser Lys Ser Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg Gly 20 25 30 Asp Asn Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3186 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3186 atctccagat ataattccaa gagcacgctg tatctgcaaa tgaacagcct gagagccgaa 60 gacacggccg tatattactg tgctaaagga aggggggaca acagctggta cgactactgg 120 ggccaggga 129 <210> 3187 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3187 Ile Ser Arg Tyr Asn Ser Lys Ser Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg Gly 20 25 30 Asp Asn Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3188 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3188 atctccagag ataattccaa gagcacgctg tatctgcaaa tgaacagcct gagagccgaa 60 gacacggccg tatattactg tgctaaagga aggggggaca acagctggta cgactactgg 120 ggccaggga 129 <210> 3189 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3189 Ile Ser Arg Asp Asn Ser Lys Ser Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg Gly 20 25 30 Asp Asn Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3190 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3190 atctccagac ataattccaa gagcacgctg tatctgcaaa tgaacagcct gagagccgaa 60 gacacggccg tatattactg tgctaaagga aggggggaca acagctggta cgactactgg 120 ggccaggga 129 <210> 3191 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3191 Ile Ser Arg His Asn Ser Lys Ser Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg Gly 20 25 30 Asp Asn Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3192 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3192 Cys Ala Lys Glu Ala Ala Ala Asp Gly Ser Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 3193 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3193 agagacaatt ccaagaacac gctgtatctg caaatgaacc gcctgagagc cgagaacacg 60 gccgtatatt actgtgcgaa agaagcagca gcagacggta gttactactt tgactactgg 120 ggccaggga 129 <210> 3194 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3194 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Arg Leu Arg 1 5 10 15 Ala Glu Asn Thr Ala Val Tyr Tyr Cys Ala Lys Glu Ala Ala Ala Asp 20 25 30 Gly Ser Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3195 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3195 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgataacacg 60 gccgtatatt actgtgcgaa agaagcagca gcagacggta gttactactt tgactactgg 120 ggccaggga 129 <210> 3196 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3196 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Asp Asn Thr Ala Val Tyr Tyr Cys Ala Lys Glu Ala Ala Ala Asp 20 25 30 Gly Ser Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3197 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3197 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agaagcagca gcagacggta gttactactt tgactactgg 120 ggccaggga 129 <210> 3198 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3198 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Ala Ala Ala Asp 20 25 30 Gly Ser Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3199 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3199 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgagaacacg 60 gccgtatatt actgtgcgaa agaagcagca gcagacggta gttactactt tgactactgg 120 ggccaggga 129 <210> 3200 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3200 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asn Thr Ala Val Tyr Tyr Cys Ala Lys Glu Ala Ala Ala Asp 20 25 30 Gly Ser Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3201 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3201 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgacaacacg 60 gccgtatatt actgtgcgaa agaagcagca gcagacggta gttactactt tgactactgg 120 ggccaggga 129 <210> 3202 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3202 agagacaatt ccaacaacac gctgtatctg caaatgaaca gcctgagagc cgagaacacg 60 gccgtatatt actgtgcgaa agaagcagca gcagacggta gttactactt tgactactgg 120 ggccaggga 129 <210> 3203 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3203 Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asn Thr Ala Val Tyr Tyr Cys Ala Lys Glu Ala Ala Ala Asp 20 25 30 Gly Ser Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3204 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3204 Cys Thr Ser Arg Ala Ala Ala Gly Pro Ile Tyr Asn Trp Phe Asp Pro 1 5 10 15 Trp <210> 3205 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3205 gttgattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagccg cgcagcagct ggacccattt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 3206 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3206 Val Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Arg Ala Ala Ala Gly Pro 20 25 30 Ile Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3207 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3207 tatgattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagccg cgcagcagct ggacccattt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 3208 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3208 Tyr Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Arg Ala Ala Ala Gly Pro 20 25 30 Ile Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3209 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3209 tttgattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagccg cgcagcagct ggacccattt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 3210 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3210 Phe Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Arg Ala Ala Ala Gly Pro 20 25 30 Ile Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3211 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3211 gttgattcaa acaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagccg cgcagcagct ggacccattt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 3212 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3212 Val Asp Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Arg Ala Ala Ala Gly Pro 20 25 30 Ile Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3213 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3213 gatgattcaa tcaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagccg cgcagcagct ggacccattt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 3214 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3214 Asp Asp Ser Ile Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Arg Ala Ala Ala Gly Pro 20 25 30 Ile Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3215 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3215 gatgattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagccg cgcagcagct ggacccattt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 3216 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3216 Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Arg Ala Ala Ala Gly Pro 20 25 30 Ile Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3217 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3217 Cys Ala Cys Gly His Thr Tyr Gly Tyr His Ile Asp Tyr Trp 1 5 10 <210> 3218 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3218 ttctccagag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagtcgga 60 gacacggccg tatattactg tgcctgtgga cacacctatg gttaccacat tgactactgg 120 ggcctggga 129 <210> 3219 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3219 Phe Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Val Gly Asp Thr Ala Val Tyr Tyr Cys Ala Cys Gly His Thr 20 25 30 Tyr Gly Tyr His Ile Asp Tyr Trp Gly Leu Gly 35 40 <210> 3220 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3220 atctccatag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagtcgga 60 gacacggccg tatattactg tgcctgtgga cacacctatg gttaccacat tgactactgg 120 ggcctggga 129 <210> 3221 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3221 Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Val Gly Asp Thr Ala Val Tyr Tyr Cys Ala Cys Gly His Thr 20 25 30 Tyr Gly Tyr His Ile Asp Tyr Trp Gly Leu Gly 35 40 <210> 3222 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3222 atctccagag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagtcgga 60 gacacggccg tatattactg tgcctgtgga cacacctatg gttaccacat tgactactgg 120 ggcctggga 129 <210> 3223 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3223 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Val Gly Asp Thr Ala Val Tyr Tyr Cys Ala Cys Gly His Thr 20 25 30 Tyr Gly Tyr His Ile Asp Tyr Trp Gly Leu Gly 35 40 <210> 3224 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3224 atctccagag acaattccaa caacacgctg tatctgcaaa tgaacagcct gagagtcgga 60 gacacggccg tatattactg tgcctgtgga cacacctatg gttaccacat tgactactgg 120 ggcctggga 129 <210> 3225 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3225 Ile Ser Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Val Gly Asp Thr Ala Val Tyr Tyr Cys Ala Cys Gly His Thr 20 25 30 Tyr Gly Tyr His Ile Asp Tyr Trp Gly Leu Gly 35 40 <210> 3226 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3226 atctccagac acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagtcgga 60 gacacggccg tatattactg tgcctgtgga cacacctatg gttaccacat tgactactgg 120 ggcctggga 129 <210> 3227 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3227 Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Val Gly Asp Thr Ala Val Tyr Tyr Cys Ala Cys Gly His Thr 20 25 30 Tyr Gly Tyr His Ile Asp Tyr Trp Gly Leu Gly 35 40 <210> 3228 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3228 atctccagac acaattccaa caacacgctg tatctgcaaa tgaacagcct gagagtcgga 60 gacacggccg tatattactg tgcctgtgga cacacctatg gttaccacat tgactactgg 120 ggcctggga 129 <210> 3229 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3229 Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Val Gly Asp Thr Ala Val Tyr Tyr Cys Ala Cys Gly His Thr 20 25 30 Tyr Gly Tyr His Ile Asp Tyr Trp Gly Leu Gly 35 40 <210> 3230 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3230 Cys Ala Arg Gly Gly Gly Trp Gly Met Thr Thr Leu Pro Pro Asp Tyr 1 5 10 15 Trp <210> 3231 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3231 gacacgtcta agaaccagtt ctccctgaag ctgagctctg tgactgccgc ggacacggcc 60 gtgtattact gtgcgagagg ggggggttgg ggcatgacta ctttaccccc cgactactgg 120 ggccaggga 129 <210> 3232 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3232 Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala 1 5 10 15 Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Gly Trp Gly Met 20 25 30 Thr Thr Leu Pro Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 3233 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3233 gacacgtcta agaaccagtt ctccctgaag ctgagctctg tgactgccgc ggacacggcc 60 gtgtattact gtgcgagagg gggggggtgg ggcatgacta ctttaccccc cgactactgg 120 ggccaggga 129 <210> 3234 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3234 gacacgtcta agaaccagtt ctccctgaag ctgagctctg tgactgccgc ggacacggcc 60 gtgtattact gtgcgagagg ggggggatgg ggcatgacta ctttaccccc cgactactgg 120 ggccaggga 129 <210> 3235 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3235 gacacgtcta acaaccagtt ctccctgaag ctgagctctg tgactgccgc ggacacggcc 60 gtgtattact gtgcgagagg ggggggttgg ggcatgacta ctttaccccc cgactactgg 120 ggccaggga 129 <210> 3236 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3236 Asp Thr Ser Asn Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala 1 5 10 15 Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Gly Trp Gly Met 20 25 30 Thr Thr Leu Pro Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 3237 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3237 gacacgtcta acaaccagtt ctccctgaag ctgagctctg tgactgccgc ggacacggcc 60 gtgtattact gtgcgagagg gggggggtgg ggcatgacta ctttaccccc cgactactgg 120 ggccaggga 129 <210> 3238 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3238 Cys Ala Lys Asn Ala Asn Asn Ile Val Asp Tyr Leu Asp Val Trp 1 5 10 15 <210> 3239 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3239 tccagagaca actccaagaa cacattgttt ctgcatttga atggcctgcg ggccggagac 60 acggccgtat atttttgtgc gaaaaacgcc aacaacatcg tcgactattt ggacgtctgg 120 ggccgaggg 129 <210> 3240 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3240 Ser Arg Asp Asn Ser Lys Asn Thr Leu Phe Leu His Leu Asn Gly Leu 1 5 10 15 Arg Ala Gly Asp Thr Ala Val Tyr Phe Cys Ala Lys Asn Ala Asn Asn 20 25 30 Ile Val Asp Tyr Leu Asp Val Trp Gly Arg Gly 35 40 <210> 3241 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3241 tccagacaca actccaacaa cacattgttt ctgcatttga atggcctgcg ggccggagac 60 acggccgtat atttttgtgc gaaaaacgcc aacaacatcg tcgactattt ggacgtctgg 120 ggccgaggg 129 <210> 3242 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3242 Ser Arg His Asn Ser Asn Asn Thr Leu Phe Leu His Leu Asn Gly Leu 1 5 10 15 Arg Ala Gly Asp Thr Ala Val Tyr Phe Cys Ala Lys Asn Ala Asn Asn 20 25 30 Ile Val Asp Tyr Leu Asp Val Trp Gly Arg Gly 35 40 <210> 3243 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3243 tccacagaca actccaagaa cacattgttt ctgcatttga atggcctgcg ggccggagac 60 acggccgtat atttttgtgc gaaaaacgcc aacaacatcg tcgactattt ggacgtctgg 120 ggccgaggg 129 <210> 3244 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3244 Ser Thr Asp Asn Ser Lys Asn Thr Leu Phe Leu His Leu Asn Gly Leu 1 5 10 15 Arg Ala Gly Asp Thr Ala Val Tyr Phe Cys Ala Lys Asn Ala Asn Asn 20 25 30 Ile Val Asp Tyr Leu Asp Val Trp Gly Arg Gly 35 40 <210> 3245 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3245 tccacagaca actccaacaa cacattgttt ctgcatttga atggcctgcg ggccggagac 60 acggccgtat atttttgtgc gaaaaacgcc aacaacatcg tcgactattt ggacgtctgg 120 ggccgaggg 129 <210> 3246 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3246 Ser Thr Asp Asn Ser Asn Asn Thr Leu Phe Leu His Leu Asn Gly Leu 1 5 10 15 Arg Ala Gly Asp Thr Ala Val Tyr Phe Cys Ala Lys Asn Ala Asn Asn 20 25 30 Ile Val Asp Tyr Leu Asp Val Trp Gly Arg Gly 35 40 <210> 3247 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3247 tccacacaca actccaagaa cacattgttt ctgcatttga atggcctgcg ggccggagac 60 acggccgtat atttttgtgc gaaaaacgcc aacaacatcg tcgactattt ggacgtctgg 120 ggccgaggg 129 <210> 3248 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3248 Ser Thr His Asn Ser Lys Asn Thr Leu Phe Leu His Leu Asn Gly Leu 1 5 10 15 Arg Ala Gly Asp Thr Ala Val Tyr Phe Cys Ala Lys Asn Ala Asn Asn 20 25 30 Ile Val Asp Tyr Leu Asp Val Trp Gly Arg Gly 35 40 <210> 3249 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3249 accacacaca actccaacaa cacattgttt ctgcatttga atggccggcg ggccggagac 60 acggccgtat atttttgtgc gaaaaacgcc aacaacatcg tcgactattt ggacgtctgg 120 ggccgaggg 129 <210> 3250 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3250 Thr Thr His Asn Ser Asn Asn Thr Leu Phe Leu His Leu Asn Gly Arg 1 5 10 15 Arg Ala Gly Asp Thr Ala Val Tyr Phe Cys Ala Lys Asn Ala Asn Asn 20 25 30 Ile Val Asp Tyr Leu Asp Val Trp Gly Arg Gly 35 40 <210> 3251 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3251 Cys Ala Lys Gly Lys Arg Gly Leu Gly His Leu Asp Tyr Trp 1 5 10 <210> 3252 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3252 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagga aagagggggc tgggacacct tgactactgg 120 ggccaggga 129 <210> 3253 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3253 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Lys Arg 20 25 30 Gly Leu Gly His Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 3254 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3254 atctccatag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagga aagagggggc tgggacacct tgactactgg 120 ggccaggga 129 <210> 3255 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3255 Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Lys Arg 20 25 30 Gly Leu Gly His Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 3256 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3256 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagga aagagggggc tgggacacct tgactactgg 120 ggccaggga 129 <210> 3257 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3257 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Lys Arg 20 25 30 Gly Leu Gly His Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 3258 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3258 atctccagat ataattccaa gaacacgctg tgtctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagga aagagggggc tgggacacct tgactactgg 120 ggccaggga 129 <210> 3259 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3259 Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Cys Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Lys Arg 20 25 30 Gly Leu Gly His Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 3260 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3260 atctccagag ataattccaa gaacacgctg tgtctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagga aagagggggc tgggacacct tgactactgg 120 ggccaggga 129 <210> 3261 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3261 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Cys Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Lys Arg 20 25 30 Gly Leu Gly His Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 3262 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3262 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagga aagagggggc tgggacacct tgactactgg 120 ggccaggga 129 <210> 3263 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3263 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Lys Arg 20 25 30 Gly Leu Gly His Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 3264 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3264 Cys Ala Lys Asp Pro Pro Ala Tyr Gly Met Asp Val Trp 1 5 10 <210> 3265 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3265 accttctcca gagataattc caagagcacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gatcccccgg cctatggtat ggacgtctgg 120 ggccgaggg 129 <210> 3266 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3266 Thr Phe Ser Arg Asp Asn Ser Lys Ser Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro 20 25 30 Pro Ala Tyr Gly Met Asp Val Trp Gly Arg Gly 35 40 <210> 3267 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3267 accatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gatcccccgg cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3268 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3268 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro 20 25 30 Pro Ala Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3269 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3269 accatctcca tacataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gatcccccgg cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3270 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3270 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro 20 25 30 Pro Ala Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3271 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3271 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gatcccccgg cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3272 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3272 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro 20 25 30 Pro Ala Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3273 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3273 accatctcca gacataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gatcccccgg cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3274 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3274 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro 20 25 30 Pro Ala Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3275 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3275 aacatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gatcccccgg cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3276 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3276 Asn Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro 20 25 30 Pro Ala Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3277 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3277 Cys Ala Arg Ala Tyr Arg Pro Tyr Tyr Phe Asp Tyr Trp 1 5 10 <210> 3278 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3278 tccatctcca tacacaactc caagaacacg ctgtatcttc aaatgaatag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gcatatcgac cgtattactt tgactactgg 120 ggccaggga 129 <210> 3279 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3279 Ser Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Tyr 20 25 30 Arg Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3280 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3280 accatctcca tacacaactc caagaacacg ctgtatcttc aaatgaatag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gcatatcgac cgtattactt tgactactgg 120 ggccaggga 129 <210> 3281 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3281 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Tyr 20 25 30 Arg Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3282 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3282 accatctcca gagacaactc caagaacacg ctgtatcttc aaatgaatag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gcatatcgac cgtattactt tgactactgg 120 ggccaggga 129 <210> 3283 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3283 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Tyr 20 25 30 Arg Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3284 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3284 accatctcca gacacaactc caagaacacg ctgtatcttc aaatgaatag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gcatatcgac cgtattactt tgactactgg 120 ggccaggga 129 <210> 3285 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3285 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Tyr 20 25 30 Arg Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3286 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3286 accatctcca cacacaactc caagaacacg ctgtatcttc aaatgaatag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gcatatcgac cgtattactt tgactactgg 120 ggccaggga 129 <210> 3287 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3287 Thr Ile Ser Thr His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Tyr 20 25 30 Arg Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3288 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3288 Cys Ala Lys Asp Leu Ala Tyr Gly His Ala Phe Asp Tyr Trp 1 5 10 <210> 3289 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3289 ttctccagag acaattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat ctggcctatg gccacgcctt tgactactgg 120 ggccaggga 129 <210> 3290 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3290 Phe Ser Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Ala 20 25 30 Tyr Gly His Ala Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3291 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3291 ttctccagac acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat ctggcctatg gccacgcctt tgactactgg 120 ggccaggga 129 <210> 3292 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3292 Phe Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Ala 20 25 30 Tyr Gly His Ala Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3293 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3293 atctccatac acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat ctggcctatg gccacgcctt tgactactgg 120 ggccaggga 129 <210> 3294 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3294 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Ala 20 25 30 Tyr Gly His Ala Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3295 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3295 atctccagag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat ctggcctatg gccacgcctt tgactactgg 120 ggccaggga 129 <210> 3296 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3296 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Ala 20 25 30 Tyr Gly His Ala Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3297 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3297 atctccagac acaattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat ctggcctatg gccacgcctt tgactactgg 120 ggccaggga 129 <210> 3298 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3298 Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Ala 20 25 30 Tyr Gly His Ala Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3299 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3299 Cys Ala Asn Thr Arg Leu Val Ala Ala Thr Pro Arg Gly Thr Trp 1 5 10 15 <210> 3300 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3300 tccagagaca attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaacacacgt ctggtagctg ctactcccag aggtacctgg 120 ggccaggga 129 <210> 3301 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3301 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Asn Thr Arg Leu Val 20 25 30 Ala Ala Thr Pro Arg Gly Thr Trp Gly Gln Gly 35 40 <210> 3302 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3302 tccagacaca attccaacaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaacacacgt ctggtagctg ctactcccag aggtacctgg 120 ggccaggga 129 <210> 3303 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3303 Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Asn Thr Arg Leu Val 20 25 30 Ala Ala Thr Pro Arg Gly Thr Trp Gly Gln Gly 35 40 <210> 3304 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3304 tccacagaca attccaagaa cacgctgtat ctgcaaatga accgcctgag agccgaggac 60 acggccgtat attactgtgc gaacacacgt ctggtagctg ctactcccag aggtacctgg 120 ggccaggga 129 <210> 3305 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3305 Ser Thr Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Arg Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Asn Thr Arg Leu Val 20 25 30 Ala Ala Thr Pro Arg Gly Thr Trp Gly Gln Gly 35 40 <210> 3306 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3306 tccacagaca attccaacaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaacacacgt ctggtagctg ctactcccag aggtacctgg 120 ggccaggga 129 <210> 3307 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3307 Ser Thr Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Asn Thr Arg Leu Val 20 25 30 Ala Ala Thr Pro Arg Gly Thr Trp Gly Gln Gly 35 40 <210> 3308 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3308 tccacacaca attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaacacacgt ctggtagctg ctactcccag aggtacctgg 120 ggccaggga 129 <210> 3309 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3309 Ser Thr His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Asn Thr Arg Leu Val 20 25 30 Ala Ala Thr Pro Arg Gly Thr Trp Gly Gln Gly 35 40 <210> 3310 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3310 Cys Ala Arg Gly Gly Gln Glu Gly Pro Gly Gly Asp Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 3311 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3311 ttaagcacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagag gcggacagga agggccgggg ggagactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3312 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3312 Leu Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Gly Gln Glu Gly Pro Gly Gly Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3313 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3313 ataagcacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagag gcggacagga agggccgggg ggagactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3314 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3314 Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Gly Gln Glu Gly Pro Gly Gly Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3315 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3315 ataaccacag cctacttgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagag gcggacagga agggccgggg ggagactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3316 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3316 Ile Thr Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Gly Gln Glu Gly Pro Gly Gly Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3317 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3317 ataaccacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagag gcggacagga agggccgggg ggagactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3318 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3318 Ile Thr Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Gly Gln Glu Gly Pro Gly Gly Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3319 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3319 ataaccacac cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagag gcggacagga agggccgggg ggagactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3320 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3320 Ile Thr Thr Pro Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Gly Gln Glu Gly Pro Gly Gly Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3321 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3321 Cys Ala Arg Asp Lys Trp Ala Ala Gly Thr Gly Tyr Trp 1 5 10 <210> 3322 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3322 accatctcca tacacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gataagtggg cagctggtac gggctactgg 120 ggccaggga 129 <210> 3323 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3323 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Lys 20 25 30 Trp Ala Ala Gly Thr Gly Tyr Trp Gly Gln Gly 35 40 <210> 3324 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3324 accatctcca gagacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gataagtggg cagctggtac gggctactgg 120 ggccaggga 129 <210> 3325 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3325 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Lys 20 25 30 Trp Ala Ala Gly Thr Gly Tyr Trp Gly Gln Gly 35 40 <210> 3326 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3326 accatctcca gacacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gataagtggg cagctggtac gggctactgg 120 ggccaggga 129 <210> 3327 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3327 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Lys 20 25 30 Trp Ala Ala Gly Thr Gly Tyr Trp Gly Gln Gly 35 40 <210> 3328 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3328 accatctcca gacacaattc caagaacacg ctgtatcttc aaatcaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gataagtggg cagctggtac gggctactgg 120 ggccaggga 129 <210> 3329 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3329 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Lys 20 25 30 Trp Ala Ala Gly Thr Gly Tyr Trp Gly Gln Gly 35 40 <210> 3330 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3330 aacatctcca tagacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gataagtggg cagctggtac gggctactgg 120 ggccaggga 129 <210> 3331 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3331 Asn Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Lys 20 25 30 Trp Ala Ala Gly Thr Gly Tyr Trp Gly Gln Gly 35 40 <210> 3332 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3332 Cys Val Arg Glu Pro Thr Gly Gly Arg Leu Phe Asp Tyr Trp 1 5 10 <210> 3333 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3333 atcaacgcag acacatccac gaaccaggtc tccctgcagc tgagctctat gactcccgag 60 gacacggcta tgtattactg tgtcagagag ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 3334 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3334 Ile Asn Ala Asp Thr Ser Thr Asn Gln Val Ser Leu Gln Leu Ser Ser 1 5 10 15 Met Thr Pro Glu Asp Thr Ala Met Tyr Tyr Cys Val Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3335 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3335 atcaacgcag acacatccac gaaccaggtc tccctgcagc tgaactctgt gactcccgag 60 gacacggcta tgtattactg tgtcagagag ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 3336 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3336 Ile Asn Ala Asp Thr Ser Thr Asn Gln Val Ser Leu Gln Leu Asn Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Met Tyr Tyr Cys Val Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3337 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3337 atcaacgcag acacatccac gaaccaggtc tccctgcagc tgaactctat gactcccgag 60 gacacggcta tgtattactg tgtcagagag ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 3338 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3338 Ile Asn Ala Asp Thr Ser Thr Asn Gln Val Ser Leu Gln Leu Asn Ser 1 5 10 15 Met Thr Pro Glu Asp Thr Ala Met Tyr Tyr Cys Val Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3339 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3339 atcaacgcac acacatccac gaaccaggtc tccctgcagc tgaactctgt gactcccgag 60 gacacggcta tgtattactg tgtcagagag ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 3340 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3340 Ile Asn Ala His Thr Ser Thr Asn Gln Val Ser Leu Gln Leu Asn Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Met Tyr Tyr Cys Val Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3341 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3341 atcaacgcac acacatccac gaaccagggc tccctgcagc tgagctctat gactcccgag 60 gacacggcta tgtattactg tgtcagagag ccgactgggg gccgactctt tgactactgg 120 ggccaggga 129 <210> 3342 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3342 Ile Asn Ala His Thr Ser Thr Asn Gln Gly Ser Leu Gln Leu Ser Ser 1 5 10 15 Met Thr Pro Glu Asp Thr Ala Met Tyr Tyr Cys Val Arg Glu Pro Thr 20 25 30 Gly Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3343 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3343 Cys Ala Arg Leu Tyr Ser Ser Ser Trp Tyr Phe Ile Arg Gly Trp Phe 1 5 10 15 Asp Pro Trp <210> 3344 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3344 tccaaaaccc tggtggtcct tacaatgacc aacatggacc ctgtggacac agccacgtat 60 tactgtgcac ggctctatag cagcagctgg tactttatcc gtggctggtt cgacccctgg 120 ggccaggga 129 <210> 3345 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3345 Ser Lys Thr Leu Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala Arg Leu Tyr Ser Ser Ser Trp Tyr Phe 20 25 30 Ile Arg Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3346 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3346 tccaaaaccc cggtggtcct tacaatgacc aacatggacc ctgtggacac agccacgtat 60 tactgtgcac ggctctatag cagcagctgg tactttatcc gtggctggtt cgacccctgg 120 ggccaggga 129 <210> 3347 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3347 Ser Lys Thr Pro Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala Arg Leu Tyr Ser Ser Ser Trp Tyr Phe 20 25 30 Ile Arg Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3348 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3348 tccaaaaacc aggtggtcct tacaatgacc aacatggacc ctgtggacac agccacgtat 60 tactgtgcac ggctctatag cagcagctgg tactttatcc gtggctggtt cgacccctgg 120 ggccaggga 129 <210> 3349 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3349 Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala Arg Leu Tyr Ser Ser Ser Trp Tyr Phe 20 25 30 Ile Arg Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3350 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3350 tcaaaaaacc aggtggtcct tacaatgacc aacatggacc ctgtggacac agccacttat 60 tactgtgcac ggctctatag cagcagctgg tactttatcc gtggctggtt cgacccctgg 120 ggccaggga 129 <210> 3351 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3351 ctccaaaacc aggtggtcct tacaatgacc aacatggacc ctgtggacac agccacgtat 60 tactgtgcac ggctctatag cagcagctgg tactttatcc gtggctggtt cgacccctgg 120 ggccaggga 129 <210> 3352 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3352 Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala Arg Leu Tyr Ser Ser Ser Trp Tyr Phe 20 25 30 Ile Arg Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3353 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3353 Cys Leu Arg Asp Trp Pro Pro Gly Asn Phe Trp 1 5 10 <210> 3354 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3354 cggttcacca tctccagata caattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagacgagg acacggccgt atattactgt cttagagact ggccccctgg gaacttctgg 120 ggccaggga 129 <210> 3355 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3355 Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr Cys Leu Arg 20 25 30 Asp Trp Pro Pro Gly Asn Phe Trp Gly Gln Gly 35 40 <210> 3356 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3356 cggttcacca tctccagata caattccaag aacacgctgt atctgcaaat caacagcctg 60 agagacgagg acacggccgt atattactgt cttagagact ggccccctgg gaacttctgg 120 ggccaggga 129 <210> 3357 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3357 Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr Cys Leu Arg 20 25 30 Asp Trp Pro Pro Gly Asn Phe Trp Gly Gln Gly 35 40 <210> 3358 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3358 cggttcacca tctccagaga caattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagacgagg acacggccgt atattactgt cttagagact ggccccctgg gaacttctgg 120 ggccaggga 129 <210> 3359 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3359 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr Cys Leu Arg 20 25 30 Asp Trp Pro Pro Gly Asn Phe Trp Gly Gln Gly 35 40 <210> 3360 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3360 cggttcacca tctccagaca caattccaag aacacgctgt atctgcaaat caacagcctg 60 agagacgagg acacggccgt atattactgt cttagagact ggccccctgg gaacttctgg 120 ggccaggga 129 <210> 3361 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3361 Arg Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr Cys Leu Arg 20 25 30 Asp Trp Pro Pro Gly Asn Phe Trp Gly Gln Gly 35 40 <210> 3362 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3362 cggttcacca tctccagaca aaattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagacgagg acacggccgt atattactgt cttagagact ggccccctgg gaacttctgg 120 ggccaggga 129 <210> 3363 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3363 Arg Phe Thr Ile Ser Arg Gln Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr Cys Leu Arg 20 25 30 Asp Trp Pro Pro Gly Asn Phe Trp Gly Gln Gly 35 40 <210> 3364 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3364 Cys Ala Leu His Tyr Gly Ser Gly Arg Ser Phe Asp Tyr Trp 1 5 10 <210> 3365 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3365 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgttacac tatggttcgg ggcggagctt tgactactgg 120 ggccaggga 129 <210> 3366 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3366 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Leu His Tyr Gly 20 25 30 Ser Gly Arg Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3367 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3367 atctccatat ataattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgttacac tatggttcgg ggcggagctt tgactactgg 120 ggccaggga 129 <210> 3368 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3368 Ile Ser Ile Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Leu His Tyr Gly 20 25 30 Ser Gly Arg Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3369 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3369 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgttacac tatggttcgg ggcggagctt tgactactgg 120 ggccaggga 129 <210> 3370 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3370 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Leu His Tyr Gly 20 25 30 Ser Gly Arg Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3371 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3371 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgttacac tatggttcgg ggcggagctt tgactactgg 120 ggccaggga 129 <210> 3372 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3372 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Leu His Tyr Gly 20 25 30 Ser Gly Arg Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3373 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3373 atctccagac ataattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgttacac tatggttcgg ggcggagctt tgactactgg 120 ggccaggga 129 <210> 3374 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3374 Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Leu His Tyr Gly 20 25 30 Ser Gly Arg Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3375 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3375 Cys Ala Lys Gly Asn Arg Asp Ser Gly Trp Thr Pro Trp 1 5 10 <210> 3376 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3376 accatctcca tagacaattc caagaacacg ctctatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ggtaatcggg acagtggctg gaccccctgg 120 ggccaggga 129 <210> 3377 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3377 Thr Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Asn 20 25 30 Arg Asp Ser Gly Trp Thr Pro Trp Gly Gln Gly 35 40 <210> 3378 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3378 accatctcca tacacaattc caagaacacg ctctatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ggtaatcggg acagtggctg gaccccctgg 120 ggccaggga 129 <210> 3379 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3379 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Asn 20 25 30 Arg Asp Ser Gly Trp Thr Pro Trp Gly Gln Gly 35 40 <210> 3380 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3380 accatctcca gagacaattc caagaacacg ctctatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ggtaatcggg acagtggctg gaccccctgg 120 ggccaggga 129 <210> 3381 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3381 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Asn 20 25 30 Arg Asp Ser Gly Trp Thr Pro Trp Gly Gln Gly 35 40 <210> 3382 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3382 accatctcca gacacaattc caagaacacg ctctatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ggtaatcggg acagtggctg gaccccctgg 120 ggccaggga 129 <210> 3383 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3383 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Asn 20 25 30 Arg Asp Ser Gly Trp Thr Pro Trp Gly Gln Gly 35 40 <210> 3384 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3384 accatctcca cacacaattc caagaacacg ctctatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ggtaatcggg acagtggctg gaccccctgg 120 ggccaggga 129 <210> 3385 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3385 Thr Ile Ser Thr His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Asn 20 25 30 Arg Asp Ser Gly Trp Thr Pro Trp Gly Gln Gly 35 40 <210> 3386 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3386 Cys Ala Lys Asp Arg Val Asp Gly Tyr Gly Asp Tyr Pro Trp 1 5 10 <210> 3387 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3387 atctccatag acaattccaa gaatactctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattcctg tgcgaaagac cgtgtggacg gctacggtga ctatccctgg 120 ggccaggga 129 <210> 3388 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3388 Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Ser Cys Ala Lys Asp Arg Val 20 25 30 Asp Gly Tyr Gly Asp Tyr Pro Trp Gly Gln Gly 35 40 <210> 3389 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3389 atctccatac acaattccaa gaatactctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattcctg tgcgaaagac cgtgtggacg gctacggtga ctatccctgg 120 ggccaggga 129 <210> 3390 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3390 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Ser Cys Ala Lys Asp Arg Val 20 25 30 Asp Gly Tyr Gly Asp Tyr Pro Trp Gly Gln Gly 35 40 <210> 3391 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3391 atctccagag acaattccaa gaatactctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattcctg tgcgaaagac cgtgtggacg gctacggtga ctatccctgg 120 ggccaggga 129 <210> 3392 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3392 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Ser Cys Ala Lys Asp Arg Val 20 25 30 Asp Gly Tyr Gly Asp Tyr Pro Trp Gly Gln Gly 35 40 <210> 3393 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3393 atctccagac acaattccaa taatactctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattcctg tgcgaaagac cgtgtggacg gctacggtga ctatccctgg 120 ggccaggga 129 <210> 3394 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3394 Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Ser Cys Ala Lys Asp Arg Val 20 25 30 Asp Gly Tyr Gly Asp Tyr Pro Trp Gly Gln Gly 35 40 <210> 3395 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3395 atctccacag acaattccaa taatactctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattcctg tgcgaaagac cgtgtggacg gctacggtga ctatccctgg 120 ggccaggga 129 <210> 3396 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3396 Ile Ser Thr Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Ser Cys Ala Lys Asp Arg Val 20 25 30 Asp Gly Tyr Gly Asp Tyr Pro Trp Gly Gln Gly 35 40 <210> 3397 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3397 Cys Val Arg Glu Pro Ser Asn Thr Leu Tyr Phe Asp Phe Trp 1 5 10 <210> 3398 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3398 ttgaccgggg acacgtccac gagcacagtc tacatggaac tgagcagcct gagatctgag 60 gacacggccg tgtatttctg tgtgagagag ccctctaata ctctgtactt tgacttctgg 120 ggccaggga 129 <210> 3399 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3399 Leu Thr Gly Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Phe Cys Val Arg Glu Pro Ser 20 25 30 Asn Thr Leu Tyr Phe Asp Phe Trp Gly Gln Gly 35 40 <210> 3400 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3400 ttgaccgggg acacgtccac gagcacagtc tacatggaac tgagcagcct gagatctgag 60 gacacggccg tgtatttctg tgtgagagag ccctccaata ctctgtactt tgacttctgg 120 ggccaggga 129 <210> 3401 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3401 atgaccgggg gcacgtccac gagcacagtc tacatggaac tgagcagcct gagatctgag 60 gacacggccg tgtatttctg tgtgagagag ccctccaata ctctgtactt tgacttctgg 120 ggccaggga 129 <210> 3402 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3402 Met Thr Gly Gly Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Phe Cys Val Arg Glu Pro Ser 20 25 30 Asn Thr Leu Tyr Phe Asp Phe Trp Gly Gln Gly 35 40 <210> 3403 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3403 atgaccgggg acacgtccac gagcacagtc tacatggaac tgagcagcct gagatctgag 60 gacacggccg tgtatttctg tgtgagagag ccctctaata ctctgtactt tgacttctgg 120 ggccaggga 129 <210> 3404 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3404 Met Thr Gly Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Phe Cys Val Arg Glu Pro Ser 20 25 30 Asn Thr Leu Tyr Phe Asp Phe Trp Gly Gln Gly 35 40 <210> 3405 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3405 atgaccgggg acacgtccac gagcacagtc tacatggaac tgagcagcct gagatctgag 60 gacacggccg tgtatttctg tgtgagagag ccctccaata ctctgtactt tgacttctgg 120 ggccaggga 129 <210> 3406 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3406 Cys Ala Arg Asp Leu Asp Lys Ser Gly Asp Trp Tyr Phe Asp Leu Trp 1 5 10 15 <210> 3407 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3407 cggacaaatc ccacgaccac agcctacatg gaactgacca gcctgagacc tgaggacacg 60 gccatgtatt tctgtgcgcg agatctagat aaatctgggg actggtactt cgatctctgg 120 ggccgtggc 129 <210> 3408 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3408 Arg Thr Asn Pro Thr Thr Thr Ala Tyr Met Glu Leu Thr Ser Leu Arg 1 5 10 15 Pro Glu Asp Thr Ala Met Tyr Phe Cys Ala Arg Asp Leu Asp Lys Ser 20 25 30 Gly Asp Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 3409 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3409 gcgtacaaac ccacgaccac agcctacatg gaactgacca gcctgagacc tgaggacacg 60 gccatgtatt tctgtgcgcg agatctagat aaatctgggg actggtactt cgatctctgg 120 ggccgtggc 129 <210> 3410 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3410 Ala Tyr Lys Pro Thr Thr Thr Ala Tyr Met Glu Leu Thr Ser Leu Arg 1 5 10 15 Pro Glu Asp Thr Ala Met Tyr Phe Cys Ala Arg Asp Leu Asp Lys Ser 20 25 30 Gly Asp Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 3411 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3411 gcggacaaat ccacgaccac agcctacatg gaactgacca gcctgagacc tgaggacacg 60 gccatgtatt tctgtgcgcg agatctagat aaatctgggg actggtactt cgatctctgg 120 ggccgtggc 129 <210> 3412 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3412 Ala Asp Lys Ser Thr Thr Thr Ala Tyr Met Glu Leu Thr Ser Leu Arg 1 5 10 15 Pro Glu Asp Thr Ala Met Tyr Phe Cys Ala Arg Asp Leu Asp Lys Ser 20 25 30 Gly Asp Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 3413 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3413 gcggaaaaac ccacgaccac agcctacatg gaactgacca gcctgagacc tgaggacacg 60 gccatgtatt tctgtgcgcg agatctagat aaatctgggg actggtactt cgatctctgg 120 ggccgtggc 129 <210> 3414 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3414 Ala Glu Lys Pro Thr Thr Thr Ala Tyr Met Glu Leu Thr Ser Leu Arg 1 5 10 15 Pro Glu Asp Thr Ala Met Tyr Phe Cys Ala Arg Asp Leu Asp Lys Ser 20 25 30 Gly Asp Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 3415 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3415 gcgaacaaac ccacgaccac agcctacatg gaactgacca gcctgagacc tgaggacacg 60 gccatgtatt tctgtgcgcg agatctagat aaatctgggg actggtactt cgatctctgg 120 ggccgtggc 129 <210> 3416 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3416 Ala Asn Lys Pro Thr Thr Thr Ala Tyr Met Glu Leu Thr Ser Leu Arg 1 5 10 15 Pro Glu Asp Thr Ala Met Tyr Phe Cys Ala Arg Asp Leu Asp Lys Ser 20 25 30 Gly Asp Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 3417 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3417 Cys Ala Arg Gly Gly Asp Tyr Tyr Gly Asp Trp 1 5 10 <210> 3418 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3418 cgattcacca tctccagaga caattccaag aacacgctgt atcttcaaat gaacagcctg 60 agagccgaag acacggccgt gtattactgt gcgagaggcg gtgactacta cggggactgg 120 ggccaggga 129 <210> 3419 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3419 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Gly Gly Asp Tyr Tyr Gly Asp Trp Gly Gln Gly 35 40 <210> 3420 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3420 cgattcacca tctccagaga caattccaac aacacgctgt atcttcaaat caacagcctg 60 agagccgaag acacggccgt gtattactgt gcgagaggcg gtgactacta cggggactgg 120 ggccaggga 129 <210> 3421 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3421 Arg Phe Thr Ile Ser Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Gly Gly Asp Tyr Tyr Gly Asp Trp Gly Gln Gly 35 40 <210> 3422 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3422 cgattcacca tctccagaga caataccaag aacacgctgt atcttcaaat caacagcctg 60 agagccgaag acacggccgt gtattactgt gcgagaggcg gtgactacta cggggactgg 120 ggccaggga 129 <210> 3423 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3423 Arg Phe Thr Ile Ser Arg Asp Asn Thr Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Gly Gly Asp Tyr Tyr Gly Asp Trp Gly Gln Gly 35 40 <210> 3424 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3424 cgattcacca tctccagaca caattccaag aacacgctgt atcttcaaat caacagcctg 60 agagccgaag acacggccgt gtattactgt gcgagaggcg gtgactacta cggggactgg 120 ggccaggga 129 <210> 3425 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3425 Arg Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Gly Gly Asp Tyr Tyr Gly Asp Trp Gly Gln Gly 35 40 <210> 3426 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3426 cgatacacca tctccagaga caattccaag aacacgctgt atcttcaaat caacagcctg 60 agagccgaag acacggccgt gtattactgt gcgagaggcg gtgactacta cggggactgg 120 ggccaggga 129 <210> 3427 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3427 Arg Tyr Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Gly Gly Asp Tyr Tyr Gly Asp Trp Gly Gln Gly 35 40 <210> 3428 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3428 Cys Ala Lys Arg Val Val Leu Ala Ala Asp Ala Phe Asp Val Trp 1 5 10 15 <210> 3429 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3429 acctgggaca cctccataac cacagcctac atggagctga gcagcctgag atctgaagac 60 acggccgtat attactgtgc gaaaagggtg gtattagctg ccgacgcttt tgatgtctgg 120 ggccaaggg 129 <210> 3430 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3430 Thr Trp Asp Thr Ser Ile Thr Thr Ala Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Arg Val Val Leu 20 25 30 Ala Ala Asp Ala Phe Asp Val Trp Gly Gln Gly 35 40 <210> 3431 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3431 accagggaca cctccataac cacagcctac atggagctga gcggcctgag atctgaagac 60 acggccgtat attactgtgc gaaaagggtg gtattagctg ccgacgcttt tgatgtctgg 120 ggccaaggg 129 <210> 3432 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3432 Thr Arg Asp Thr Ser Ile Thr Thr Ala Tyr Met Glu Leu Ser Gly Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Arg Val Val Leu 20 25 30 Ala Ala Asp Ala Phe Asp Val Trp Gly Gln Gly 35 40 <210> 3433 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3433 accagggaca cctccataac cacagcctac atggagctga gcagcctgag atctgaagac 60 acggccgtat attactgtgc gaaaagggtg gtattagctg ccgacgcttt tgatgtctgg 120 ggccaaggg 129 <210> 3434 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3434 Thr Arg Asp Thr Ser Ile Thr Thr Ala Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Arg Val Val Leu 20 25 30 Ala Ala Asp Ala Phe Asp Val Trp Gly Gln Gly 35 40 <210> 3435 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3435 accagggaca cctccataac cacaccctac atggagctga gcagcctgag atctgaagac 60 acggccgtat attactgtgc gaaaagggtg gtattagctg ccgacgcttt tgatgtctgg 120 ggccaaggg 129 <210> 3436 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3436 Thr Arg Asp Thr Ser Ile Thr Thr Pro Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Arg Val Val Leu 20 25 30 Ala Ala Asp Ala Phe Asp Val Trp Gly Gln Gly 35 40 <210> 3437 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3437 accaggcaca cctccataac cacagcctac atggagctga gcagcctgag atctgaagac 60 acggccgtat attactgtgc gaaaagggtg gtattagctg ccgacgcttt tgatgtctgg 120 ggccaaggg 129 <210> 3438 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3438 Thr Arg His Thr Ser Ile Thr Thr Ala Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Arg Val Val Leu 20 25 30 Ala Ala Asp Ala Phe Asp Val Trp Gly Gln Gly 35 40 <210> 3439 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3439 Cys Ala Lys Gln Ile Gly Gly Tyr Ser Tyr Gly Tyr Thr Asp Val Trp 1 5 10 15 <210> 3440 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3440 tgtgatagct ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa acaaattggt ggatacagct atggttatac ggacgtctgg 120 ggccaaggg 129 <210> 3441 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3441 Cys Asp Ser Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gln Ile Gly Gly Tyr 20 25 30 Ser Tyr Gly Tyr Thr Asp Val Trp Gly Gln Gly 35 40 <210> 3442 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3442 atatataact ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa acaaattggt ggatacagct atggttatac ggacgtctgg 120 ggccaaggg 129 <210> 3443 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3443 Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gln Ile Gly Gly Tyr 20 25 30 Ser Tyr Gly Tyr Thr Asp Val Trp Gly Gln Gly 35 40 <210> 3444 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3444 agatataact ccaacaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa acaaattggt ggatacagct atggttatac ggacgtctgg 120 ggccaaggg 129 <210> 3445 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3445 Arg Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gln Ile Gly Gly Tyr 20 25 30 Ser Tyr Gly Tyr Thr Asp Val Trp Gly Gln Gly 35 40 <210> 3446 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3446 agagatagct ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa acaaattggt ggatacagct atggttatac ggacgtctgg 120 ggccaaggg 129 <210> 3447 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3447 Arg Asp Ser Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gln Ile Gly Gly Tyr 20 25 30 Ser Tyr Gly Tyr Thr Asp Val Trp Gly Gln Gly 35 40 <210> 3448 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3448 agagataact ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa acaaattggt ggatacagct atggttatac ggacgtctgg 120 ggccaaggg 129 <210> 3449 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3449 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gln Ile Gly Gly Tyr 20 25 30 Ser Tyr Gly Tyr Thr Asp Val Trp Gly Gln Gly 35 40 <210> 3450 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3450 Cys Ala Lys Gly Leu Trp Phe Gly Gly Gly Trp Phe Asp Pro Trp 1 5 10 15 <210> 3451 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3451 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggacta tggttcgggg ggggctggtt cgacccctgg 120 ggccaggga 129 <210> 3452 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3452 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Trp Phe 20 25 30 Gly Gly Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3453 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3453 tccagagata attccaacaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggacta tggttcgggg ggggctggtt cgacccctgg 120 ggccaggga 129 <210> 3454 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3454 Ser Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Trp Phe 20 25 30 Gly Gly Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3455 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3455 tccagacata attccaacaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggacta tggttcgggg ggggctggtt cgacccctgg 120 ggccaggga 129 <210> 3456 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3456 Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Trp Phe 20 25 30 Gly Gly Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3457 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3457 tccacagata attccaacaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggacta tggttcgggg ggggctggtt cgacccctgg 120 ggccaggga 129 <210> 3458 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3458 Ser Thr Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Trp Phe 20 25 30 Gly Gly Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3459 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3459 tacagagata attccaagaa cacgctgtat ctgcaaatga accgcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggacta tggttcgggg ggggctggtt cgacccctgg 120 ggccaggga 129 <210> 3460 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3460 Tyr Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Arg Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Trp Phe 20 25 30 Gly Gly Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3461 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3461 Cys Ala Lys Asn Ser Gly Tyr Asp Tyr Tyr Phe Asp Tyr Trp 1 5 10 <210> 3462 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3462 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaaat agtggctacg attactactt tgactactgg 120 ggccaggga 129 <210> 3463 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3463 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asn Ser Gly 20 25 30 Tyr Asp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3464 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3464 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaaat agtggctacg attactactt tgactactgg 120 ggccaggga 129 <210> 3465 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3465 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asn Ser Gly 20 25 30 Tyr Asp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3466 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3466 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacgaccg tatattactg tgcgaaaaat agtggctacg attactactt tgactactgg 120 ggccaggga 129 <210> 3467 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3467 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Thr Val Tyr Tyr Cys Ala Lys Asn Ser Gly 20 25 30 Tyr Asp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3468 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3468 atctccagag ataattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacgaccg tatattactg tgcgaaaaat agtggctacg attactactt tgactactgg 120 ggccaggga 129 <210> 3469 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3469 Ile Ser Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Thr Val Tyr Tyr Cys Ala Lys Asn Ser Gly 20 25 30 Tyr Asp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3470 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3470 atctccagac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacgaccg tatattactg tgcgaaaaat agtggctacg attactactt tgactactgg 120 ggccaggga 129 <210> 3471 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3471 Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Thr Val Tyr Tyr Cys Ala Lys Asn Ser Gly 20 25 30 Tyr Asp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3472 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3472 Cys Ala Arg Asp Ser Ser Gly Trp Ser Arg Asp Tyr Trp 1 5 10 <210> 3473 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3473 accatctcca tagattattc caagaacact ctgtatctgc aaatgaacag cctgagagtc 60 gaagacacgg ccatatatta ctgtgcgaga gatagtagtg gctggtcccg tgattactgg 120 ggccaggga 129 <210> 3474 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3474 Thr Ile Ser Ile Asp Tyr Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Val Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Asp Ser 20 25 30 Ser Gly Trp Ser Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 3475 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3475 accatctcca tagatgattc caagaacact ctgtatctgc aaatgaacag cctgagagtc 60 gaagacacgg ccatatatta ctgtgcgaga gatagtagtg gctggtcccg tgattactgg 120 ggccaggga 129 <210> 3476 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3476 Thr Ile Ser Ile Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Val Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Asp Ser 20 25 30 Ser Gly Trp Ser Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 3477 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3477 accatctcca gagattattc caagaacact ctgtatctgc aaatgaacag cctgagagtc 60 gaagacacgg ccatatatta ctgtgcgaga gatagtagtg gctggtcccg tgattactgg 120 ggccaggga 129 <210> 3478 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3478 Thr Ile Ser Arg Asp Tyr Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Val Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Asp Ser 20 25 30 Ser Gly Trp Ser Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 3479 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3479 accatctcca gagatgattc caagaacact ctgtatctgc aaatgaacag cctgagagtc 60 gaagacacgg ccatatatta ctgtgcgaga gatagtagtg gctggtcccg tgattactgg 120 ggccaggga 129 <210> 3480 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3480 Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Val Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Asp Ser 20 25 30 Ser Gly Trp Ser Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 3481 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3481 aacatctcca gatattattc caagaacact ctgtatctgc aaatgaacag cctgagaggc 60 gaacacacgg ccatatatta ctgtgcgaga gatagtagtg gctggtcccg tgattactgg 120 ggccaggga 129 <210> 3482 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3482 Asn Ile Ser Arg Tyr Tyr Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Gly Glu His Thr Ala Ile Tyr Tyr Cys Ala Arg Asp Ser 20 25 30 Ser Gly Trp Ser Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 3483 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3483 Cys Ile Arg Gly Gly Ser Pro Asp Tyr Phe Asp Tyr Trp 1 5 10 <210> 3484 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3484 tgcatttcca gagatcattc aaagaacacg gcgtatctgc agatgaacag cctgaaaacc 60 gaagacacgg ccgtctatta ttgtatcaga ggtgggagcc ctgactactt tgactattgg 120 ggccaggga 129 <210> 3485 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3485 Cys Ile Ser Arg Asp His Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ile Arg Gly Gly 20 25 30 Ser Pro Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3486 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3486 tgcatttcca gacatgattc aaagaacacg gcgtatctgc agatgaacag cctgaaaacc 60 gaagacacgg ccgtctatta ttgtatcaga ggtgggagcc ctgactactt tgactattgg 120 ggccaggga 129 <210> 3487 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3487 Cys Ile Ser Arg His Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ile Arg Gly Gly 20 25 30 Ser Pro Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3488 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3488 agcatttcca gagatgattc aaagaacacg gcgtatctgc agatgaacag cctgaaaacc 60 gaagacacgg ccgtctatta ttgtatcaga ggtgggagcc ctgactactt tgactattgg 120 ggccaggga 129 <210> 3489 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3489 Ser Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ile Arg Gly Gly 20 25 30 Ser Pro Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3490 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3490 agcatttcca gacatcattc aaagaacacg gcgtatctgc agatgaacag cctgaaaacc 60 gaagacacgg ccgtctatta ttgtatcaga ggtgggagcc ctgactactt tgactattgg 120 ggccaggga 129 <210> 3491 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3491 Ser Ile Ser Arg His His Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ile Arg Gly Gly 20 25 30 Ser Pro Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3492 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3492 accatttcca gacatgattc aaagaacacg gcgtatctgc agatgaacag cctgaaaacc 60 gaagacacgg ccgtctatta ttgtatcaga ggtgggagcc ctgactactt tgactattgg 120 ggccaggga 129 <210> 3493 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3493 Thr Ile Ser Arg His Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ile Arg Gly Gly 20 25 30 Ser Pro Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3494 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3494 Cys Ala Thr Leu Trp Phe Gly Glu Ser Asn Asp Tyr Trp 1 5 10 <210> 3495 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3495 accatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgact ctatggttcg gggagtcgaa tgactactgg 120 ggccaggga 129 <210> 3496 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3496 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Leu Trp 20 25 30 Phe Gly Glu Ser Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 3497 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3497 accatctcca tacataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgact ctatggttcg gggagtcgaa tgactactgg 120 ggccaggga 129 <210> 3498 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3498 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Leu Trp 20 25 30 Phe Gly Glu Ser Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 3499 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3499 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgact ctatggttcg gggagtcgaa tgactactgg 120 ggccaggga 129 <210> 3500 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3500 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Leu Trp 20 25 30 Phe Gly Glu Ser Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 3501 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3501 aacatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgact ctatggttcg gggagtcgaa tgactactgg 120 ggccaggga 129 <210> 3502 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3502 Asn Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Leu Trp 20 25 30 Phe Gly Glu Ser Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 3503 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3503 aacatctcca gatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgact ctatggttcg gggagtcgaa tgactactgg 120 ggccaggga 129 <210> 3504 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3504 Asn Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Leu Trp 20 25 30 Phe Gly Glu Ser Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 3505 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3505 Cys Ala Lys Asp Arg Ser Asp Pro Pro Trp Ile Phe Gly Val Val Met 1 5 10 15 Gly Tyr Tyr Gly Met Asp Val Trp 20 <210> 3506 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3506 tttctgaaaa tgaacagcct gagagccgag gacacggccg tatattactg tgcgaaagat 60 cggagtgatc ccccttggat ttttggagtg gttatgggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3507 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3507 Phe Leu Lys Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Arg Ser Asp Pro Pro Trp Ile Phe Gly Val Val Met 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3508 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3508 tttatgcaaa tgaacagcct gagagccgag gacacggccg tatattactg tgcgaaagat 60 cggagtgatc ccccttggat ttttggagtg gttatgggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3509 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3509 Phe Met Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Arg Ser Asp Pro Pro Trp Ile Phe Gly Val Val Met 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3510 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3510 tatctgcaaa tgaacagcct gagagccgag gacacggccg tatattactg tgcgaaagat 60 cggagtgatc ccccttggat ttttggagtg gttatgggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3511 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3511 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Arg Ser Asp Pro Pro Trp Ile Phe Gly Val Val Met 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3512 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3512 tatctgaaaa tcaacagcct gagagccgag gacacggccg tatattactg tgcgaaagat 60 cggagtgatc ccccttggat ttttggagtg gttatgggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3513 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3513 Tyr Leu Lys Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Arg Ser Asp Pro Pro Trp Ile Phe Gly Val Val Met 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3514 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3514 tatatgaaaa tgaacagcct gagagccgag gacacggccg tatattactg tgcgaaagat 60 cggagtgatc ccccttggat ttttggagtg gttatgggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3515 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3515 Tyr Met Lys Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Arg Ser Asp Pro Pro Trp Ile Phe Gly Val Val Met 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3516 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3516 Cys Ala Arg Gly Gly Gly Glu Phe Asp Cys Trp 1 5 10 <210> 3517 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3517 cggttcacca tctccagaga caaatccaag aacacgctgt ttctgcaaat ggacagcctg 60 agagccgagg acacggccat atatttctgt gcgagggggg gtggtgagtt tgactgctgg 120 ggccaggga 129 <210> 3518 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3518 Arg Phe Thr Ile Ser Arg Asp Lys Ser Lys Asn Thr Leu Phe Leu Gln 1 5 10 15 Met Asp Ser Leu Arg Ala Glu Asp Thr Ala Ile Tyr Phe Cys Ala Arg 20 25 30 Gly Gly Gly Glu Phe Asp Cys Trp Gly Gln Gly 35 40 <210> 3519 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3519 cggttcacca tctccagaca caaatccaag aacacgctgt ttctgcaaat ggacagcctg 60 agagccgagg acacggccat atatttctgt gcgagggggg gtggtgagtt tgactgctgg 120 ggccaggga 129 <210> 3520 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3520 Arg Phe Thr Ile Ser Arg His Lys Ser Lys Asn Thr Leu Phe Leu Gln 1 5 10 15 Met Asp Ser Leu Arg Ala Glu Asp Thr Ala Ile Tyr Phe Cys Ala Arg 20 25 30 Gly Gly Gly Glu Phe Asp Cys Trp Gly Gln Gly 35 40 <210> 3521 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3521 cggttcacca tctccagaca caaaaccaag aacacgctgt ttctgcaaat ggacagcctg 60 agagccgagg acacggccat atatttctgt gcgagggggg gtggtgagtt tgactgctgg 120 ggccaggga 129 <210> 3522 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3522 Arg Phe Thr Ile Ser Arg His Lys Thr Lys Asn Thr Leu Phe Leu Gln 1 5 10 15 Met Asp Ser Leu Arg Ala Glu Asp Thr Ala Ile Tyr Phe Cys Ala Arg 20 25 30 Gly Gly Gly Glu Phe Asp Cys Trp Gly Gln Gly 35 40 <210> 3523 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3523 cggttcacca tctccacaga caaatccaag aacacgctgt ttctgcaaat ggacagcctg 60 agagccgagg acacggccat atatttctgt gcgagggggg gtggtgagtt tgactgctgg 120 ggccaggga 129 <210> 3524 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3524 Arg Phe Thr Ile Ser Thr Asp Lys Ser Lys Asn Thr Leu Phe Leu Gln 1 5 10 15 Met Asp Ser Leu Arg Ala Glu Asp Thr Ala Ile Tyr Phe Cys Ala Arg 20 25 30 Gly Gly Gly Glu Phe Asp Cys Trp Gly Gln Gly 35 40 <210> 3525 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3525 cggatcacca tctccagaca caaatccaag aacacgctgt ttctgcaaat ggacagcctg 60 agagccgagg acacggccat atatttctgt gcgagggggg gtggtgagtt tgactgctgg 120 ggccaggga 129 <210> 3526 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3526 Arg Ile Thr Ile Ser Arg His Lys Ser Lys Asn Thr Leu Phe Leu Gln 1 5 10 15 Met Asp Ser Leu Arg Ala Glu Asp Thr Ala Ile Tyr Phe Cys Ala Arg 20 25 30 Gly Gly Gly Glu Phe Asp Cys Trp Gly Gln Gly 35 40 <210> 3527 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3527 Cys Ala Arg Glu Gly Gly Ala Pro Ser Tyr Asn Trp Phe Asp Pro Trp 1 5 10 15 <210> 3528 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3528 tggaacacct ccataagcac agcctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agaggggggg gccccctcgt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 3529 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3529 Trp Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly Gly Ala Pro 20 25 30 Ser Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3530 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3530 agtaacacct ccataagcac agcctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agaggggggg gccccctcgt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 3531 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3531 Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly Gly Ala Pro 20 25 30 Ser Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3532 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3532 aggaacacct ccatacgcac agcctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agaggggggg gccccctcgt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 3533 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3533 Arg Asn Thr Ser Ile Arg Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly Gly Ala Pro 20 25 30 Ser Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3534 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3534 aggaacacct ccataagcac agcctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agaggggggg gccccctcgt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 3535 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3535 Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly Gly Ala Pro 20 25 30 Ser Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3536 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3536 aggaacacct ccataaccac agcctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agaggggggg gccccctcgt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 3537 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3537 Arg Asn Thr Ser Ile Thr Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly Gly Ala Pro 20 25 30 Ser Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3538 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3538 Cys Ala Lys Thr Tyr Asp Tyr Gly Asp Tyr Val Gly Tyr Trp 1 5 10 <210> 3539 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3539 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaacc tatgactacg gtgactacgt gggctactgg 120 ggccaggga 129 <210> 3540 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3540 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr Tyr Asp 20 25 30 Tyr Gly Asp Tyr Val Gly Tyr Trp Gly Gln Gly 35 40 <210> 3541 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3541 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaacc tatgactacg gtgactacgt gggctactgg 120 ggccaggga 129 <210> 3542 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3542 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr Tyr Asp 20 25 30 Tyr Gly Asp Tyr Val Gly Tyr Trp Gly Gln Gly 35 40 <210> 3543 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3543 atctccagat ataattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaacc tatgactacg gtgactacgt gggctactgg 120 ggccaggga 129 <210> 3544 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3544 Ile Ser Arg Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr Tyr Asp 20 25 30 Tyr Gly Asp Tyr Val Gly Tyr Trp Gly Gln Gly 35 40 <210> 3545 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3545 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaacc tatgactacg gtgactacgt gggctactgg 120 ggccaggga 129 <210> 3546 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3546 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr Tyr Asp 20 25 30 Tyr Gly Asp Tyr Val Gly Tyr Trp Gly Gln Gly 35 40 <210> 3547 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3547 atctccagac ataattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaacc tatgactacg gtgactacgt gggctactgg 120 ggccaggga 129 <210> 3548 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3548 Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr Tyr Asp 20 25 30 Tyr Gly Asp Tyr Val Gly Tyr Trp Gly Gln Gly 35 40 <210> 3549 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3549 Cys Ala Lys Asp Leu Trp Arg Gly Gly Leu Phe Asp Tyr Trp 1 5 10 <210> 3550 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3550 atctccatag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat ctttggaggg ggggtctctt tgactactgg 120 ggccaggga 129 <210> 3551 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3551 Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Trp 20 25 30 Arg Gly Gly Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3552 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3552 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat ctttggaggg ggggtctctt tgactactgg 120 ggccaggga 129 <210> 3553 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3553 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Trp 20 25 30 Arg Gly Gly Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3554 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3554 atctccagat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat ctttggaggg ggggtctctt tgactactgg 120 ggccaggga 129 <210> 3555 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3555 Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Trp 20 25 30 Arg Gly Gly Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3556 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3556 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat ctttggaggg ggggtctctt tgactactgg 120 ggccaggga 129 <210> 3557 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3557 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Trp 20 25 30 Arg Gly Gly Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3558 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3558 atctccagac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat ctttggaggg ggggtctctt tgactactgg 120 ggccaggga 129 <210> 3559 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3559 Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Trp 20 25 30 Arg Gly Gly Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3560 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3560 Cys Gly Gly Ser Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 1 5 10 <210> 3561 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3561 accatctcca tagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgggggg tcatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3562 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3562 Thr Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Gly Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3563 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3563 accatctcca gatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgggggg tcatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3564 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3564 Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Gly Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3565 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3565 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgggggg tcatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3566 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3566 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Gly Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3567 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3567 accatctcca gagataattc caagaacacg ctgtatctgc aaatcaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgggggg tcatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3568 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3568 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Gly Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3569 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3569 accatctcca gacataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgggggg tcatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3570 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3570 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Gly Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3571 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3571 Cys Ala Arg Asp Pro Asn Ala Glu Gly Gly Ala Val Ala Gly Pro His 1 5 10 15 Gly Met Asp Val Trp 20 <210> 3572 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3572 tgcacagcct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatc ccaacgccga agggggagca gtggctggtc cccacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3573 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3573 Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Pro Asn Ala Glu Gly Gly Ala Val Ala 20 25 30 Gly Pro His Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3574 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3574 tgcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatc ccaacgccga agggggagca gtggctggtc cccacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3575 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3575 Cys Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Pro Asn Ala Glu Gly Gly Ala Val Ala 20 25 30 Gly Pro His Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3576 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3576 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatc ccaacgccga agggggagca gtggctggtc cccacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3577 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3577 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Pro Asn Ala Glu Gly Gly Ala Val Ala 20 25 30 Gly Pro His Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3578 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3578 agcacagcct acatggagct gagcagcctg agatctgagg acacggccat gtattactgt 60 gcgagagatc ccaacgccga agggggagca gtggctggtc cccacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3579 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3579 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Met Tyr Tyr Cys Ala Arg Asp Pro Asn Ala Glu Gly Gly Ala Val Ala 20 25 30 Gly Pro His Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3580 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3580 agcacagcct acatggagct gagcagcctg agatctgagg acacagccgt gtattactgt 60 gcgagagatc ccaacgccga agggggagca gtggctggtc cccacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3581 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3581 Cys Ala Lys Ala Asp Ser Tyr Tyr Asp Ile Leu Thr Gly Phe Trp Ser 1 5 10 15 Gly Ser Tyr Asp Tyr Trp 20 <210> 3582 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3582 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagctgact cgtattacga tattttgact ggtttttggt ccggaagtta tgactactgg 120 ggccaggga 129 <210> 3583 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3583 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Ala Asp Ser Tyr Tyr Asp Ile Leu Thr Gly Phe 20 25 30 Trp Ser Gly Ser Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3584 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3584 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagctgact cgtattacga tattttgact ggtttttggt ccggaagtta tgactactgg 120 ggccaggga 129 <210> 3585 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3585 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Ala Asp Ser Tyr Tyr Asp Ile Leu Thr Gly Phe 20 25 30 Trp Ser Gly Ser Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3586 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3586 acgatgtatc tgcaaatgaa cagcctgaga gccgagtaca cggccgtata ttactgtgcg 60 aaagctgact cgtattacga tattttgact ggtttttggt ccggaagtta tgactactgg 120 ggccaggga 129 <210> 3587 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3587 Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Tyr Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Ala Asp Ser Tyr Tyr Asp Ile Leu Thr Gly Phe 20 25 30 Trp Ser Gly Ser Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3588 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3588 acgatgtatc tgcaaatcaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagctgact cgtattacga tattttgact ggtttttggt ccggaagtta tgactactgg 120 ggccaggga 129 <210> 3589 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3589 Thr Met Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Ala Asp Ser Tyr Tyr Asp Ile Leu Thr Gly Phe 20 25 30 Trp Ser Gly Ser Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3590 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3590 acgatgtatc tccaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagctgact cgtattacga tattttgact ggtttttggt ccggaagtta tgactactgg 120 ggccaggga 129 <210> 3591 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3591 Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Ala Asp Ser Tyr Tyr Asp Ile Leu Thr Gly Phe 20 25 30 Trp Ser Gly Ser Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3592 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3592 Cys Ala Lys Gly Leu Ser Ala Tyr Ile Ser Phe Phe Asp Asp Trp 1 5 10 15 <210> 3593 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3593 tccagttata attcccaaaa cactctgtat ctgcaaatga acagcctgag agccgaagac 60 acggccgtat attactgtgc gaaagggcta agtgcctaca tttcgttctt tgatgactgg 120 ggccaggga 129 <210> 3594 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3594 Ser Ser Tyr Asn Ser Gln Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Ser Ala 20 25 30 Tyr Ile Ser Phe Phe Asp Asp Trp Gly Gln Gly 35 40 <210> 3595 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3595 tccagtgata attccgaaaa cactctgtat ctgcaaatga acagcctgag agccgaagac 60 acggccgtat attactgtgc gaaagggcta agtgcctaca tttcgttctt tgatgactgg 120 ggccaggga 129 <210> 3596 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3596 Ser Ser Asp Asn Ser Glu Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Ser Ala 20 25 30 Tyr Ile Ser Phe Phe Asp Asp Trp Gly Gln Gly 35 40 <210> 3597 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3597 tccagtgata attcccaaaa cactctgtat ctgcaaatga accgcctgag agccgaagac 60 acggccgtat attactgtgc gaaagggcta agtgcctaca tttcgttctt tgatgactgg 120 ggccaggga 129 <210> 3598 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3598 Ser Ser Asp Asn Ser Gln Asn Thr Leu Tyr Leu Gln Met Asn Arg Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Ser Ala 20 25 30 Tyr Ile Ser Phe Phe Asp Asp Trp Gly Gln Gly 35 40 <210> 3599 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3599 tccagtgata attcccaaaa cactctgtat ctgcaaatga acagcctgag agccgaagac 60 acggccgtat attactgtgc gaaagggcta agtgcctaca tttcgttctt tgatgactgg 120 ggccaggga 129 <210> 3600 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3600 Ser Ser Asp Asn Ser Gln Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Ser Ala 20 25 30 Tyr Ile Ser Phe Phe Asp Asp Trp Gly Gln Gly 35 40 <210> 3601 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3601 tccagtgata attcccaaaa cactctgtat ctgcaaatca acagcctgag agccgaagac 60 acggccgtat attactgtgc gaaagggcta agtgcctaca tttcgttctt tgatgactgg 120 ggccaggga 129 <210> 3602 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3602 Ser Ser Asp Asn Ser Gln Asn Thr Leu Tyr Leu Gln Ile Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Ser Ala 20 25 30 Tyr Ile Ser Phe Phe Asp Asp Trp Gly Gln Gly 35 40 <210> 3603 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3603 Cys Ala Arg Gly Arg Gly Asn Glu Asn Phe Asp Tyr Trp 1 5 10 <210> 3604 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3604 accatctcca tagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggtgacacgg ctgtgtatta ctgtgcaaga gggaggggaa acgagaactt tgactactgg 120 ggccaggga 129 <210> 3605 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3605 Thr Ile Ser Ile Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg 20 25 30 Gly Asn Glu Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3606 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3606 accatctcca tacaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggggacacgg ctgtgtatta ctgtgcaaga gggaggggaa acgagaactt tgactactgg 120 ggccaggga 129 <210> 3607 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3607 Thr Ile Ser Ile Gln Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg 20 25 30 Gly Asn Glu Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3608 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3608 accatctcca gagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggggacacgg ctgtgtatta ctgtgcaaga gggaggggaa acgagaactt tgactactgg 120 ggccaggga 129 <210> 3609 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3609 Thr Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg 20 25 30 Gly Asn Glu Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3610 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3610 aacatctcca tagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggggacacgg ctgtgtatta ctgtgcaaga gggaggggaa acgagaactt tgactactgg 120 ggccaggga 129 <210> 3611 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3611 Asn Ile Ser Ile Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg 20 25 30 Gly Asn Glu Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3612 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3612 aacatctcca gagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggtgacacgg ctgtgtatta ctgtgcaaga gggaggggaa acgagaactt tgactactgg 120 ggccaggga 129 <210> 3613 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3613 Asn Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg 20 25 30 Gly Asn Glu Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3614 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3614 Cys Thr Arg Glu Phe Trp Gly Phe Gly Glu Asp Tyr Trp 1 5 10 <210> 3615 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3615 accatctcaa gagattattc caaaagcatc gcctatctgc aaatcaacag ccttaaaacc 60 gagcacacag ccgtgtatta ctgtactaga gagttctggg ggttcgggga agactactgg 120 ggccaggga 129 <210> 3616 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3616 Thr Ile Ser Arg Asp Tyr Ser Lys Ser Ile Ala Tyr Leu Gln Ile Asn 1 5 10 15 Ser Leu Lys Thr Glu His Thr Ala Val Tyr Tyr Cys Thr Arg Glu Phe 20 25 30 Trp Gly Phe Gly Glu Asp Tyr Trp Gly Gln Gly 35 40 <210> 3617 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3617 accatctcaa gagatgattc caaaagcatc gcctatctgc aaatgaacag ccttaaaacc 60 gaggacacag ccgtgtatta ctgtactaga gagttctggg ggttcgggga agactactgg 120 ggccaggga 129 <210> 3618 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3618 Thr Ile Ser Arg Asp Asp Ser Lys Ser Ile Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Glu Phe 20 25 30 Trp Gly Phe Gly Glu Asp Tyr Trp Gly Gln Gly 35 40 <210> 3619 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3619 accatctcaa gagatgattc caaaagcatc gcctatctgc aaatgaacag cctgaaaacc 60 gaggacacag ccgtgtatta ctgtactaga gagttctggg ggttcgggga agactactgg 120 ggccaggga 129 <210> 3620 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3620 accatctcaa gagatgattc caaaagcatc gcctatctgc aaatgaacag cctgaaaacc 60 gaggacacag ccgtgtatta ctgtactaga gagttctggg ggttcggaga agactactgg 120 ggccaggga 129 <210> 3621 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3621 acaatctcaa gagatgattc caaaagcatc gcctatctgc aaatgaacag cctgaaaacc 60 gaggacacag ccgtgtatta ctgtactaga gagttctggg ggttcgggga agactactgg 120 ggccaggga 129 <210> 3622 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3622 Cys Thr Val Thr Pro Pro Tyr Gln Tyr Tyr Ala Met Asp Val Trp 1 5 10 15 <210> 3623 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3623 tccagagatt attcaaacaa cacggtgtat ctgcaaatga acagcctgaa aaccgaggac 60 acggccgtgt atttctgtac tgttactcct ccttaccagt attacgctat ggacgtctgg 120 ggccaaggg 129 <210> 3624 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3624 Ser Arg Asp Tyr Ser Asn Asn Thr Val Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Phe Cys Thr Val Thr Pro Pro Tyr 20 25 30 Gln Tyr Tyr Ala Met Asp Val Trp Gly Gln Gly 35 40 <210> 3625 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3625 tccagagatg attcaaagaa cacggtgtat ctgcaaatga acagcctgaa aaccgaggac 60 acggccgtgt atttctgtac tgttactcct ccttaccagt attacgctat ggacgtctgg 120 ggccaaggg 129 <210> 3626 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3626 Ser Arg Asp Asp Ser Lys Asn Thr Val Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Phe Cys Thr Val Thr Pro Pro Tyr 20 25 30 Gln Tyr Tyr Ala Met Asp Val Trp Gly Gln Gly 35 40 <210> 3627 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3627 tccagagatg attcaaacaa cacggtgtat ctgcaaatga acagcctcaa aaccgaggac 60 acggccgtgt atttctgtac tgttactcct ccttaccagt attacgctat ggacgtctgg 120 ggccaaggg 129 <210> 3628 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3628 Ser Arg Asp Asp Ser Asn Asn Thr Val Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Phe Cys Thr Val Thr Pro Pro Tyr 20 25 30 Gln Tyr Tyr Ala Met Asp Val Trp Gly Gln Gly 35 40 <210> 3629 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3629 tccagagatc attcaaacaa cacggtgtat ctgcaaatga acagcctgaa aaccgaggac 60 acggccgtgt atttctgtac tgttactcct ccttaccagt attacgctat ggacgtctgg 120 ggccaaggg 129 <210> 3630 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3630 Ser Arg Asp His Ser Asn Asn Thr Val Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Phe Cys Thr Val Thr Pro Pro Tyr 20 25 30 Gln Tyr Tyr Ala Met Asp Val Trp Gly Gln Gly 35 40 <210> 3631 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3631 Cys Ala Lys His Ala Arg Phe Tyr Ser Ser Ser His Thr Arg Asp Asp 1 5 10 15 Ala Phe Asp Ile Trp 20 <210> 3632 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3632 aacacgctgt ttctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaagcacg cccgtttcta tagcagcagc cacacccgcg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 3633 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3633 Asn Thr Leu Phe Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys His Ala Arg Phe Tyr Ser Ser Ser His Thr 20 25 30 Arg Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3634 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3634 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaagcacg cccgtttcta tagcagcagc cacacccgcg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 3635 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3635 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys His Ala Arg Phe Tyr Ser Ser Ser His Thr 20 25 30 Arg Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3636 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3636 aacacgctgt atctgcaaat caacagcctg agagccgagg acacggccgt atattactgt 60 gcgaagcacg cccgtttcta tagcagcagc cacacccgcg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 3637 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3637 Asn Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys His Ala Arg Phe Tyr Ser Ser Ser His Thr 20 25 30 Arg Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3638 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3638 aacacgctgt atctgaaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaagcacg cccgtttcta tagcagcagc cacacccgcg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 3639 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3639 Asn Thr Leu Tyr Leu Lys Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys His Ala Arg Phe Tyr Ser Ser Ser His Thr 20 25 30 Arg Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3640 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3640 Cys Ala Arg Gly Asp Gly Gln Leu Val Leu Pro Ser Trp 1 5 10 <210> 3641 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3641 tgtcttctcc ttggacgccc tgtcagcacg gcatatctgc agatcagcag cctaaagact 60 gaggacactg ccgtgtatta ctgtgcgaga ggggatgggc agctggtact tccgtcgtgg 120 ggccaggga 129 <210> 3642 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3642 Cys Leu Leu Leu Gly Arg Pro Val Ser Thr Ala Tyr Leu Gln Ile Ser 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp 20 25 30 Gly Gln Leu Val Leu Pro Ser Trp Gly Gln Gly 35 40 <210> 3643 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3643 gtcttctcct tggacgcctc tgtcagcacg gcatatctgc agatcagcag cctaaagact 60 gaggacactg ccgtgtatta ctgtgcgaga ggggatgggc agctggtact tccgtcgtgg 120 ggccaggga 129 <210> 3644 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3644 Val Phe Ser Leu Asp Ala Ser Val Ser Thr Ala Tyr Leu Gln Ile Ser 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp 20 25 30 Gly Gln Leu Val Leu Pro Ser Trp Gly Gln Gly 35 40 <210> 3645 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3645 gtcttctcct tggacacctc tgtcagcacg gcatatctgc agatcagcag cctaaaggct 60 gaggacactg ccgtgtatta ctgtgcgaga ggggatgggc agctggtact tccgtcgtgg 120 ggccaggga 129 <210> 3646 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3646 Val Phe Ser Leu Asp Thr Ser Val Ser Thr Ala Tyr Leu Gln Ile Ser 1 5 10 15 Ser Leu Lys Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp 20 25 30 Gly Gln Leu Val Leu Pro Ser Trp Gly Gln Gly 35 40 <210> 3647 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3647 gtcttctcct tggacacctc tgtcagcacg gcatatctgc agatcagcag cctaaagact 60 gaggacactg ccgtgtatta ctgtgcgaga ggggatgggc agctggtact tccgtcgtgg 120 ggccaggga 129 <210> 3648 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3648 Val Phe Ser Leu Asp Thr Ser Val Ser Thr Ala Tyr Leu Gln Ile Ser 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp 20 25 30 Gly Gln Leu Val Leu Pro Ser Trp Gly Gln Gly 35 40 <210> 3649 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3649 Cys Ala Lys Asp Arg Leu Gly Ala Ala Val Pro Asp Tyr Trp 1 5 10 <210> 3650 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3650 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat aggttaggag cagctgtccc tgactactgg 120 ggccaggga 129 <210> 3651 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3651 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Leu 20 25 30 Gly Ala Ala Val Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 3652 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3652 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat aggttaggag cagctgtccc tgactactgg 120 ggccaggga 129 <210> 3653 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3653 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Leu 20 25 30 Gly Ala Ala Val Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 3654 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3654 atctccagat ataattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat aggttaggag cagctgtccc tgactactgg 120 ggccaggga 129 <210> 3655 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3655 Ile Ser Arg Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Leu 20 25 30 Gly Ala Ala Val Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 3656 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3656 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat aggttaggag cagctgtccc tgactactgg 120 ggccaggga 129 <210> 3657 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3657 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Leu 20 25 30 Gly Ala Ala Val Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 3658 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3658 Cys Arg Ile Val Val Val Pro Ala Ala Asn Tyr Tyr Tyr Gly Met Asp 1 5 10 15 Val Trp <210> 3659 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3659 tattcaaaga ccacggcgta tctgcaaatg aacagcctga aaaccgagga cacggccgtg 60 tattactgtc gtattgtagt agtaccagct gcaaactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3660 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3660 Tyr Ser Lys Thr Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Arg Ile Val Val Val Pro Ala Ala Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3661 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3661 gtttcaaaga actcggcgta tctgcaaatg aacagcctga aaaccgagga cacggccgtg 60 tattactgtc gtattgtagt agtaccagct gcaaactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3662 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3662 Val Ser Lys Asn Ser Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Arg Ile Val Val Val Pro Ala Ala Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3663 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3663 gattcaaaga acacggcgta tctgcaaatg aacagcctga aaaccgagga cacggccgtg 60 tattactgtc gtattgtagt agtaccagct gcaaactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3664 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3664 Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Arg Ile Val Val Val Pro Ala Ala Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3665 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3665 attcaaagaa ccacggcgta tctgcaaatg aacagcctga aaaccgagga cacggccgtg 60 tattactgtc gtattgtagt agtaccagct gcaaactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3666 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3666 Ile Gln Arg Thr Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Arg Ile Val Val Val Pro Ala Ala Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3667 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3667 Cys Ala Lys Gly Pro Arg Pro Gly Gly Ser Trp Arg Phe Asp Tyr Trp 1 5 10 15 <210> 3668 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3668 atagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa aggcccgcga cctgggggca gctggcgctt tgactactgg 120 ggccaggga 129 <210> 3669 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3669 Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Pro Arg Pro Gly 20 25 30 Gly Ser Trp Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3670 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3670 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa aggcccgcga cctgggggca gctggcgctt tgactactgg 120 ggccaggga 129 <210> 3671 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3671 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Pro Arg Pro Gly 20 25 30 Gly Ser Trp Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3672 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3672 agagataatt ccaagaacac gctgtatctg aaaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa aggcccgcga cctgggggca gctggcgctt tgactactgg 120 ggccaggga 129 <210> 3673 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3673 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Lys Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Pro Arg Pro Gly 20 25 30 Gly Ser Trp Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3674 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3674 agagataatt ccaacaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa aggcccgcga cctgggggca gctggcgctt tgactactgg 120 ggccaggga 129 <210> 3675 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3675 Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Pro Arg Pro Gly 20 25 30 Gly Ser Trp Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3676 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3676 Cys Ala Lys Thr Arg Ser Ala Cys Phe Gln His Trp 1 5 10 <210> 3677 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3677 ttcaccatct ccagagacaa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaacccggt ccgcgtgctt ccagcactgg 120 ggccagggc 129 <210> 3678 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3678 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr 20 25 30 Arg Ser Ala Cys Phe Gln His Trp Gly Gln Gly 35 40 <210> 3679 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3679 ttcaccatct ccagagacaa taccaagaac acgctgtatc tgcaaatcaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaacccggt ccgcgtgctt ccagcactgg 120 ggccagggc 129 <210> 3680 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3680 Phe Thr Ile Ser Arg Asp Asn Thr Lys Asn Thr Leu Tyr Leu Gln Ile 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr 20 25 30 Arg Ser Ala Cys Phe Gln His Trp Gly Gln Gly 35 40 <210> 3681 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3681 ttcaccatct ccagacacaa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaacccggt ccgcgtgctt ccagcactgg 120 ggccagggc 129 <210> 3682 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3682 Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr 20 25 30 Arg Ser Ala Cys Phe Gln His Trp Gly Gln Gly 35 40 <210> 3683 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3683 ttcaccatct ccagacacaa ttccaagaac acgctgtatc tgcaaatcaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaacccggt ccgcgtgctt ccagcactgg 120 ggccagggc 129 <210> 3684 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3684 Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr 20 25 30 Arg Ser Ala Cys Phe Gln His Trp Gly Gln Gly 35 40 <210> 3685 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3685 Cys Ala Lys Pro Ala Val Thr Gly Thr Gly Tyr Trp 1 5 10 <210> 3686 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3686 ttcaccatct ccagatataa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaccggcag tgactggtac tggctattgg 120 ggccaggga 129 <210> 3687 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3687 Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro 20 25 30 Ala Val Thr Gly Thr Gly Tyr Trp Gly Gln Gly 35 40 <210> 3688 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3688 ttcaccatct ccagagataa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaccggcag tgactggtac tggctattgg 120 ggccaggga 129 <210> 3689 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3689 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro 20 25 30 Ala Val Thr Gly Thr Gly Tyr Trp Gly Gln Gly 35 40 <210> 3690 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3690 ttcaccatct ccagacataa ttccaagaac acgctgtatc tgcaaatcaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaccggcag tgactggtac tggctattgg 120 ggccaggga 129 <210> 3691 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3691 Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro 20 25 30 Ala Val Thr Gly Thr Gly Tyr Trp Gly Gln Gly 35 40 <210> 3692 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3692 ttcaccacct ccagagataa ttccgggaac acggtgtctc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaccggcag tgactggtac tggctattgg 120 ggccaggga 129 <210> 3693 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3693 Phe Thr Thr Ser Arg Asp Asn Ser Gly Asn Thr Val Ser Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro 20 25 30 Ala Val Thr Gly Thr Gly Tyr Trp Gly Gln Gly 35 40 <210> 3694 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3694 Cys Ala Arg Glu Val Gly Asp Gly Asp Gly Ser Ser Ile Gly Gly Tyr 1 5 10 15 Ala Phe Asp Ile Trp 20 <210> 3695 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3695 agcactgcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagagg tcggggacgg agatggcagc tcaatcggag ggtacgcttt tgatatctgg 120 ggccaaggg 129 <210> 3696 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3696 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Val Gly Asp Gly Asp Gly Ser Ser Ile 20 25 30 Gly Gly Tyr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3697 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3697 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagagg tcggggacgg agatggcagc tcaatcggag ggtacgcttt tgatatctgg 120 ggccaaggg 129 <210> 3698 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3698 agcacagcct acacggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagagg tcggggacgg agatggtagc tcaatcggag ggtacgcttt tgatatctgg 120 ggccaaggg 129 <210> 3699 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3699 Ser Thr Ala Tyr Thr Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Val Gly Asp Gly Asp Gly Ser Ser Ile 20 25 30 Gly Gly Tyr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3700 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3700 agcacagcct acacggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagagg tcggggacgg agatggcagc tcaatcggag ggtacgcttt tgatatctgg 120 ggccaaggg 129 <210> 3701 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3701 Cys Ala Lys Ala Pro Ser Gly Gly Val Ala Thr Pro His Ala Gly Gly 1 5 10 15 Met Asp Val Trp 20 <210> 3702 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3702 aagaacacgc tgtatctgca aatgaacagc ctgagagccg aggacacggc cgtatattac 60 tgtgcgaaag ccccttcggg tggggtggct accccccacg ccggtggtat ggacgtctgg 120 ggccaaggg 129 <210> 3703 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3703 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Ala Pro Ser Gly Gly Val Ala Thr Pro 20 25 30 His Ala Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3704 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3704 aagaacacgc tgtatctgaa aatgaacagc ctgagagccg aggacacggc cgtatattac 60 tgtgcgaaag ccccttcggg tggggtggct accccccacg ccggtggtat ggacgtctgg 120 ggccaaggg 129 <210> 3705 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3705 Lys Asn Thr Leu Tyr Leu Lys Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Ala Pro Ser Gly Gly Val Ala Thr Pro 20 25 30 His Ala Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3706 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3706 aacaacacgc tgtatctgca aatgaacagc ctgagagccg aggacacggc cgtatattac 60 tgtgcgaaag ccccttcggg tggggtggct accccccacg ccggtggtat ggacgtctgg 120 ggccaaggg 129 <210> 3707 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3707 Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Ala Pro Ser Gly Gly Val Ala Thr Pro 20 25 30 His Ala Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3708 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3708 aagaacccgc tgtatctgaa aatgaaccgc ctgagcgccg aggacacggc cgtatattac 60 tgtgcgaaag ccccttcggg tggggtggct accccccacg ccggtggtat ggacgtctgg 120 ggccaaggg 129 <210> 3709 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3709 Lys Asn Pro Leu Tyr Leu Lys Met Asn Arg Leu Ser Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Ala Pro Ser Gly Gly Val Ala Thr Pro 20 25 30 His Ala Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3710 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3710 Cys Ala Arg Val Gly Glu Thr Val Ala Ala Gly Met Val Asp Tyr Trp 1 5 10 15 <210> 3711 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3711 tgggacaacg ccaagaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgag agtgggggaa acagtagcag ctggaatggt ggactactgg 120 ggccaggga 129 <210> 3712 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3712 Trp Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly Glu Thr Val 20 25 30 Ala Ala Gly Met Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 3713 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3713 tgggacaacg ccaacaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgag agtgggggaa acagtagcag ctggaatggt ggactactgg 120 ggccaggga 129 <210> 3714 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3714 Trp Asp Asn Ala Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly Glu Thr Val 20 25 30 Ala Ala Gly Met Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 3715 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3715 agggacaacg ccaagaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgag agtgggggaa acagtagcag ctggaatggt ggactactgg 120 ggccaggga 129 <210> 3716 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3716 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly Glu Thr Val 20 25 30 Ala Ala Gly Met Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 3717 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3717 agggacaacg ccaagaactc actgtatctg caaatgaaca gcctgagagc cgacgacacg 60 gccgtgtatt actgtgcgag agtgggggag acagtagcag ctggaatggt ggactactgg 120 ggccaggga 129 <210> 3718 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3718 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly Glu Thr Val 20 25 30 Ala Ala Gly Met Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 3719 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3719 Cys Ala Arg Trp Ala Lys Val Thr Val Gly Gly Met Asp Val Trp 1 5 10 15 <210> 3720 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3720 acctgggaca cgtccgcgag cacagccgac atggagctga gaagcctgag atctgaagac 60 acggctgtat atttctgtgc gcgatgggct aaggtgactg ttgggggtat ggacgtctgg 120 ggccaaggg 129 <210> 3721 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3721 Thr Trp Asp Thr Ser Ala Ser Thr Ala Asp Met Glu Leu Arg Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Trp Ala Lys Val 20 25 30 Thr Val Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3722 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3722 acctgggaca cgcccgcgag cacagccgac atggagctga gaagcctgag atctgaagac 60 acggctgtat atttctgtgc gcgatgggct aaggtgactg ttgggggtat ggacgtctgg 120 ggccaaggg 129 <210> 3723 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3723 Thr Trp Asp Thr Pro Ala Ser Thr Ala Asp Met Glu Leu Arg Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Trp Ala Lys Val 20 25 30 Thr Val Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3724 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3724 accagggaca cgtccgcgag cacagccgac atggagctga gaagcctgag atctgaagac 60 acggctgtat atttctgtgc gcgatgggct aaggtgactg ttgggggtat ggacgtctgg 120 ggccaaggg 129 <210> 3725 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3725 Thr Arg Asp Thr Ser Ala Ser Thr Ala Asp Met Glu Leu Arg Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Trp Ala Lys Val 20 25 30 Thr Val Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3726 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3726 accagggaca cgcccgcgag cacagccgac atggagctga gaagcctgat atctgaagac 60 acggctgtat atttctgtgc gcgatgggct aaggtgactg ttgggggtat ggacgtctgg 120 ggccaaggg 129 <210> 3727 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3727 Thr Arg Asp Thr Pro Ala Ser Thr Ala Asp Met Glu Leu Arg Ser Leu 1 5 10 15 Ile Ser Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Trp Ala Lys Val 20 25 30 Thr Val Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3728 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3728 Cys Ala Arg Ala His Tyr Asp Phe Trp Ser Phe Ser Asn Pro Glu Arg 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 3729 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3729 tcgctgtatc ttcaaatgaa cagcctgaga gccgaggaca cggccgtgta ttactgtgcg 60 agagcccatt acgatttttg gagtttttcg aacccggagc gctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3730 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3730 Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Ala His Tyr Asp Phe Trp Ser Phe Ser Asn Pro 20 25 30 Glu Arg Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3731 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3731 tcgatgtatc ttcaaatgaa cagcctgaga gccgaggaca cggccgtgta ttactgtgcg 60 agagcccatt acgatttttg gagtttttcg aacccggagc gctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3732 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3732 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Ala His Tyr Asp Phe Trp Ser Phe Ser Asn Pro 20 25 30 Glu Arg Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3733 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3733 acgctgtatc ttcaaatgaa cagcctgaga gccgaggaca cggccgtgta ttactgtgcg 60 agagcccatt acgatttttg gagtttttcg aacccggagc gctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3734 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3734 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Ala His Tyr Asp Phe Trp Ser Phe Ser Asn Pro 20 25 30 Glu Arg Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3735 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3735 acgatgtatc ttcaaatcaa cagcctgaga gccgaggaca cggccgtgta ttactgtgcg 60 agagcccatt acgatttttg gagtttttcg aacccggagc gctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3736 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3736 Thr Met Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Ala His Tyr Asp Phe Trp Ser Phe Ser Asn Pro 20 25 30 Glu Arg Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3737 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3737 Cys Ala Lys Arg Gln Ile Lys Glu Gly Asp Thr Glu Ser Arg Asp Lys 1 5 10 15 Gly Ile Asp Cys Trp 20 <210> 3738 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3738 aacatgatgt atttgcaaat caacagcctg agagtcgagg acacggccct atattactgt 60 gcgaaaaggc agataaaaga gggtgacact gaatctcgcg ataaaggcat cgactgctgg 120 ggccaggga 129 <210> 3739 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3739 Asn Met Met Tyr Leu Gln Ile Asn Ser Leu Arg Val Glu Asp Thr Ala 1 5 10 15 Leu Tyr Tyr Cys Ala Lys Arg Gln Ile Lys Glu Gly Asp Thr Glu Ser 20 25 30 Arg Asp Lys Gly Ile Asp Cys Trp Gly Gln Gly 35 40 <210> 3740 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3740 aacatgatgt atttgcaaat gaacagcctg agagtcgagg acacggccct atattactgt 60 gcgaaaaggc agataaaaga gggtgacact gaatctcgcg ataaaggcat cgactgctgg 120 ggccaggga 129 <210> 3741 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3741 Asn Met Met Tyr Leu Gln Met Asn Ser Leu Arg Val Glu Asp Thr Ala 1 5 10 15 Leu Tyr Tyr Cys Ala Lys Arg Gln Ile Lys Glu Gly Asp Thr Glu Ser 20 25 30 Arg Asp Lys Gly Ile Asp Cys Trp Gly Gln Gly 35 40 <210> 3742 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3742 aacatgatgt atttccaaat caacagcctg agagtcgagg acacggccct atattactgt 60 gcgaaaaggc agataaaaga gggtgacact gaatctcgcg ataaaggcat cgactgctgg 120 ggccaggga 129 <210> 3743 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3743 Asn Met Met Tyr Phe Gln Ile Asn Ser Leu Arg Val Glu Asp Thr Ala 1 5 10 15 Leu Tyr Tyr Cys Ala Lys Arg Gln Ile Lys Glu Gly Asp Thr Glu Ser 20 25 30 Arg Asp Lys Gly Ile Asp Cys Trp Gly Gln Gly 35 40 <210> 3744 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3744 Cys Ala Lys Asp Arg Leu Ala Ala Ala Arg Trp Tyr Phe Asp Leu Trp 1 5 10 15 <210> 3745 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3745 agagacaatt ccaagaacac gctgtatctg caaatcaata gcctgagagc cgaagacacg 60 gccgtatatt actgtgcgaa agatcgccta gcagccgccc gctggtactt tgatctctgg 120 ggccgtggc 129 <210> 3746 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3746 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Leu Ala Ala 20 25 30 Ala Arg Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 3747 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3747 agagacaatt ccaacaacac gctgtatctg caaatcaatc gcctgagagc cgaagacacg 60 gccgtatatt actgtgcgaa agatcgccta gcagccgccc gctggtactt tgatctctgg 120 ggccgtggc 129 <210> 3748 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3748 Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Ile Asn Arg Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Leu Ala Ala 20 25 30 Ala Arg Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 3749 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3749 agagacaatt ccaacaacac gctgtatctg aaaatcaata gcctgagagc cgaagacacg 60 gccgtatatt actgtgcgaa agatcgccta gcagccgccc gctggtactt tgatctctgg 120 ggccgtggc 129 <210> 3750 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3750 Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Lys Ile Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Leu Ala Ala 20 25 30 Ala Arg Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 3751 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3751 agagaaaatt ccaagaacac gctgtatctg aaaatcaata gcctgagagc cgaagacacg 60 gccgtatatt actgtgcgaa agatcgccta gcagccgccc gctggtactt tgatctctgg 120 ggccgtggc 129 <210> 3752 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3752 Arg Glu Asn Ser Lys Asn Thr Leu Tyr Leu Lys Ile Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Leu Ala Ala 20 25 30 Ala Arg Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 3753 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3753 Cys Ala Lys Val Thr Thr Gly Thr Val Thr Asp Tyr Trp 1 5 10 <210> 3754 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3754 accatctcca tacacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gtaacaactg gaacagtaac tgactactgg 120 ggccaggga 129 <210> 3755 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3755 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Thr 20 25 30 Thr Gly Thr Val Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3756 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3756 accatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gtaacaactg gaacagtaac tgactactgg 120 ggccaggga 129 <210> 3757 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3757 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Thr 20 25 30 Thr Gly Thr Val Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3758 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3758 accatctcca gacacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gtaacaactg gaacagtaac tgactactgg 120 ggccaggga 129 <210> 3759 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3759 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Thr 20 25 30 Thr Gly Thr Val Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3760 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3760 accatctcca gacacaattc caacaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gtaacaactg gaacagtaac tgactactgg 120 ggccaggga 129 <210> 3761 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3761 Thr Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Thr 20 25 30 Thr Gly Thr Val Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3762 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3762 Cys Ala Lys Pro Arg Ala Arg Gln Gln Pro Leu Phe Asp Tyr Trp 1 5 10 15 <210> 3763 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3763 tccatatata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaccccgg gcgcggcagc agcccctatt tgactactgg 120 ggccaggga 129 <210> 3764 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3764 Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro Arg Ala Arg 20 25 30 Gln Gln Pro Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3765 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3765 tccagatata attccaagaa cacgctgtat ctgaaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaccccgg gcgcggcagc agcccctatt tgactactgg 120 ggccaggga 129 <210> 3766 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3766 Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Lys Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro Arg Ala Arg 20 25 30 Gln Gln Pro Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3767 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3767 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaccccgg gcgcggcagc agcccctatt tgactactgg 120 ggccaggga 129 <210> 3768 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3768 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro Arg Ala Arg 20 25 30 Gln Gln Pro Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3769 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3769 tacagatata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaccccgg gcgcggcagc agcccctatt tgactactgg 120 ggccaggga 129 <210> 3770 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3770 Tyr Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro Arg Ala Arg 20 25 30 Gln Gln Pro Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3771 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3771 Cys Thr Arg Val Arg Val Ala Gly Tyr Ser Ser Ser Trp Tyr Asp Ala 1 5 10 15 Phe Asp Ile Trp 20 <210> 3772 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3772 aagaatacgg cgtatctgca aatgaacagc ctgaaaatcg aggacacggc cgtgtattac 60 tgtactagag tgagggtcgc cgggtatagc agcagctggt acgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 3773 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3773 Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Ile Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Thr Arg Val Arg Val Ala Gly Tyr Ser Ser Ser 20 25 30 Trp Tyr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3774 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3774 aagaatacgg cgtatctgca aatgaacagc ctgaaaatcg aggacacggc cgtgtattac 60 tgtactagag tgagggtcgc cggctatagc agcagctggt acgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 3775 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3775 aagaacacgg cgtatctgca aatgaacagc ctgaaaaccg aggacacggc cgtgtattac 60 tgtactagag tgagggtcgc cgggtatagc agcagctggt acgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 3776 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3776 Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Thr Arg Val Arg Val Ala Gly Tyr Ser Ser Ser 20 25 30 Trp Tyr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3777 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3777 aacaatacgg cgtatctgca aatcaacagc ctgaaaatcg aggacacggc cgtgtattac 60 tgtactagag tgagggtcgc cgggtatagc agcagctggt acgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 3778 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3778 Asn Asn Thr Ala Tyr Leu Gln Ile Asn Ser Leu Lys Ile Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Thr Arg Val Arg Val Ala Gly Tyr Ser Ser Ser 20 25 30 Trp Tyr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3779 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3779 Cys Thr Thr Ser Gly Trp Pro Pro Tyr Tyr Tyr Tyr Gly Met Asp Val 1 5 10 15 Trp <210> 3780 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3780 tatgattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtaccaccag tggctggccc ccatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3781 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3781 Tyr Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Ser Gly Trp Pro Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3782 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3782 gattattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtaccaccag tggctggccc ccatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3783 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3783 Asp Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Ser Gly Trp Pro Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3784 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3784 tatgattcaa acaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtaccaccag tggctggccc ccatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3785 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3785 Tyr Asp Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Ser Gly Trp Pro Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3786 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3786 gatgattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtaccaccag tggctggccc ccatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3787 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3787 Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Ser Gly Trp Pro Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3788 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3788 Cys Ala Lys Gly Gly Ser Ser Trp Tyr Tyr Phe Asp Tyr Trp 1 5 10 <210> 3789 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3789 ttctccagac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaggg ggcagcagct ggtactactt tgactactgg 120 ggccaggga 129 <210> 3790 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3790 Phe Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Ser 20 25 30 Ser Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3791 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3791 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaggg ggcagcagct ggtactactt tgactactgg 120 ggccaggga 129 <210> 3792 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3792 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Ser 20 25 30 Ser Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3793 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3793 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaggg ggcagcagct ggtactactt tgactactgg 120 ggccaggga 129 <210> 3794 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3794 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Ser 20 25 30 Ser Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3795 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3795 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaggg ggcagcagct ggtactactt tgactactgg 120 ggccaggga 129 <210> 3796 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3796 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Ser 20 25 30 Ser Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3797 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3797 Cys Ala Lys Asp His Ile Ala Leu Asp Gly Leu Trp Asp Ser Asp Tyr 1 5 10 15 Trp <210> 3798 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3798 gacgactcca agaacacgat gtttctccac atgaacagac tgagagtcga cgacacggcc 60 gtatatttct gtgcgaaaga ccacattgcc cttgatggcc tctgggactc tgactactgg 120 ggccaggga 129 <210> 3799 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3799 Asp Asp Ser Lys Asn Thr Met Phe Leu His Met Asn Arg Leu Arg Val 1 5 10 15 Asp Asp Thr Ala Val Tyr Phe Cys Ala Lys Asp His Ile Ala Leu Asp 20 25 30 Gly Leu Trp Asp Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 3800 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3800 cacgactcca agaacacgat gtttctccac atgaacagac tgagagtcga cgacacggcc 60 gtatatttct gtgcgaaaga ccacattgcc cttgatggcc tctgggactc tgactactgg 120 ggccaggga 129 <210> 3801 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3801 His Asp Ser Lys Asn Thr Met Phe Leu His Met Asn Arg Leu Arg Val 1 5 10 15 Asp Asp Thr Ala Val Tyr Phe Cys Ala Lys Asp His Ile Ala Leu Asp 20 25 30 Gly Leu Trp Asp Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 3802 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3802 Cys Val Arg Asp Arg Lys Ser Arg Gly Trp Phe Pro Asp Asp Val Phe 1 5 10 15 Asp Met Trp <210> 3803 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3803 gctaataatt cagtgtattt gcagatgaac aacctgagag acgaggacac ggctctatat 60 ttttgtgtca gagatcggaa gagtagaggc tggttccccg atgatgtttt tgatatgtgg 120 ggccaaggg 129 <210> 3804 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3804 Ala Asn Asn Ser Val Tyr Leu Gln Met Asn Asn Leu Arg Asp Glu Asp 1 5 10 15 Thr Ala Leu Tyr Phe Cys Val Arg Asp Arg Lys Ser Arg Gly Trp Phe 20 25 30 Pro Asp Asp Val Phe Asp Met Trp Gly Gln Gly 35 40 <210> 3805 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3805 gcgaataatt ctgtgtattt gcagatgaac aacctgagag acgaggacac ggctctatat 60 ttttgtgtca gagatcggaa gagtagaggc tggttccccg atgatgtttt tgatatgtgg 120 ggccaaggg 129 <210> 3806 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3806 gcgaagaatt cagtgtattt gcagatgaac aacctgagag acgaggacac ggctctatat 60 ttttgtgtca gagatcggaa gagtagaggc tggttccccg atgatgtttt tgatatgtgg 120 ggccaaggg 129 <210> 3807 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3807 Ala Lys Asn Ser Val Tyr Leu Gln Met Asn Asn Leu Arg Asp Glu Asp 1 5 10 15 Thr Ala Leu Tyr Phe Cys Val Arg Asp Arg Lys Ser Arg Gly Trp Phe 20 25 30 Pro Asp Asp Val Phe Asp Met Trp Gly Gln Gly 35 40 <210> 3808 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3808 gcgaagaatt atgtgtattt gcagatgaac aacctgagag acgaggacac ggctctatat 60 ttttgtgtca gagatcggaa gagtagaggc tggttccccg atgatgtttt tgatatgtgg 120 ggccaaggg 129 <210> 3809 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3809 Ala Lys Asn Tyr Val Tyr Leu Gln Met Asn Asn Leu Arg Asp Glu Asp 1 5 10 15 Thr Ala Leu Tyr Phe Cys Val Arg Asp Arg Lys Ser Arg Gly Trp Phe 20 25 30 Pro Asp Asp Val Phe Asp Met Trp Gly Gln Gly 35 40 <210> 3810 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3810 Cys Thr His Asn Val Gly Gly Trp Asp Gly Pro Tyr Ser Asp Tyr Trp 1 5 10 15 <210> 3811 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3811 aaggacacct ccaaaaaccg ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt tctgtacaca caatgttgga ggctgggatg ggccgtactc tgactactgg 120 ggccaggga 129 <210> 3812 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3812 Lys Asp Thr Ser Lys Asn Arg Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Phe Cys Thr His Asn Val Gly Gly Trp 20 25 30 Asp Gly Pro Tyr Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 3813 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3813 aaggacacct ccaaaaaccg ggtggtcctc acaatgacca acatggaccc tgtggacaca 60 gccacatatt tctgtacaca caatgttgga ggctgggatg ggccgtactc tgactactgg 120 ggccaggga 129 <210> 3814 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3814 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatgggccc tgtggacaca 60 gccacatatt actgtacaca caatgttgga ggctgggatg gcccgtactc tgactactgg 120 ggccaggga 129 <210> 3815 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3815 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Gly 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Thr His Asn Val Gly Gly Trp 20 25 30 Asp Gly Pro Tyr Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 3816 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3816 aaggacacct ccaaaaacca ggtggtcctg accatgtcca acatggaccc tgtggacaca 60 gccacatatt actgtacaca caatgttgga ggctgggatg ggccgtactc tgactactgg 120 ggccaggga 129 <210> 3817 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3817 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Ser Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Thr His Asn Val Gly Gly Trp 20 25 30 Asp Gly Pro Tyr Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 3818 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3818 Cys Thr Thr Gln Gly Ser Gln Gly Met Asp Val Trp 1 5 10 <210> 3819 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3819 ttcaccatct ccttagatga ctcaaagaac acggcgtatc tgcaaatgaa cagcctgaaa 60 gccgaggaca cggccgtata ttactgtact acccagggat cacagggcat ggacgtctgg 120 ggccaaggg 129 <210> 3820 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3820 Phe Thr Ile Ser Leu Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Ala Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Gln 20 25 30 Gly Ser Gln Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3821 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3821 ttcaccatct ccagagatga ctcaaagaac acggcgtatc tgcaaatgaa cagcctgaag 60 gccgaggata cggccgtata ttactgtact acccagggat cacagggcat ggacgtctgg 120 ggccaaggg 129 <210> 3822 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3822 Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Ala Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Gln 20 25 30 Gly Ser Gln Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3823 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3823 ttcaccatct ccagagatga ctcaaagaac acggcgtatc tgcaaatgaa cagcctgaaa 60 gccgaggaca cggccgtata ttactgtact acccagggat cacagggcat ggacgtctgg 120 ggccaaggg 129 <210> 3824 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3824 ttcaccatct ccagacatta ctcaaagaac acggcgtatc tgcaaatgaa cagcctgaaa 60 gccgaggaca cggccgtata ttactgtact acccagggat cacagggcat ggacgtctgg 120 ggccaaggg 129 <210> 3825 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3825 Phe Thr Ile Ser Arg His Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Ala Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Gln 20 25 30 Gly Ser Gln Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3826 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3826 Cys Ala Ser Gly Arg Glu Ala Gly Tyr Trp 1 5 10 <210> 3827 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3827 ggcagagtca ccatgaccag gaacacctcc ataagcacag cctacatgga gctgagcagc 60 ctgagatctg aggacacggc cgtgtattac tgtgcgagtg ggagggaggc agggtactgg 120 ggccaggga 129 <210> 3828 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3828 Gly Arg Val Thr Met Thr Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met 1 5 10 15 Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Ser Gly Arg Glu Ala Gly Tyr Trp Gly Gln Gly 35 40 <210> 3829 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3829 ggcagagtca ccatgaccag caacacctcc ataagcacag cctacatgga gctgagcagc 60 ctgatatctg aggacacggc cgtgtattac tgtgcgagtg ggagggaggc agggtactgg 120 ggccaggga 129 <210> 3830 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3830 Gly Arg Val Thr Met Thr Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met 1 5 10 15 Glu Leu Ser Ser Leu Ile Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Ser Gly Arg Glu Ala Gly Tyr Trp Gly Gln Gly 35 40 <210> 3831 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3831 ggcagagtca ccatgaccag caacacctcc ataagcacag cctacatgga gctgagcagc 60 ctgagatctg aggacacggc cgtgtattac tgtgcgagtg ggagggaggc agggtactgg 120 ggccaggga 129 <210> 3832 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3832 Gly Arg Val Thr Met Thr Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met 1 5 10 15 Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Ser Gly Arg Glu Ala Gly Tyr Trp Gly Gln Gly 35 40 <210> 3833 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3833 ggcagagtca ccatgaccag caacacctcc ataaccacag cctacatgga gctgagcagc 60 ctgagatctg aggacacggc cgtgtattac tgtgcgagtg ggagggaggc agggtactgg 120 ggccaggga 129 <210> 3834 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3834 Gly Arg Val Thr Met Thr Ser Asn Thr Ser Ile Thr Thr Ala Tyr Met 1 5 10 15 Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Ser Gly Arg Glu Ala Gly Tyr Trp Gly Gln Gly 35 40 <210> 3835 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3835 Cys Ala Lys Leu Leu Ser Val Arg Ser Tyr Phe Asp Tyr Trp 1 5 10 <210> 3836 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3836 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaactc ctcagcgtcc gtagctactt tgactactgg 120 ggccaggga 129 <210> 3837 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3837 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Leu Leu Ser 20 25 30 Val Arg Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3838 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3838 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaactc ctcagcgtcc gtagctactt tgactactgg 120 ggccaggga 129 <210> 3839 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3839 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Leu Leu Ser 20 25 30 Val Arg Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3840 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3840 atctccagat ataattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaactc ctcagcgtcc gtagctactt tgactactgg 120 ggccaggga 129 <210> 3841 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3841 Ile Ser Arg Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Leu Leu Ser 20 25 30 Val Arg Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3842 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3842 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaactc ctcagcgtcc gtagctactt tgactactgg 120 ggccaggga 129 <210> 3843 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3843 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Leu Leu Ser 20 25 30 Val Arg Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3844 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3844 Cys Ala Arg Gly Gly Ser Asp Asn Trp His Leu Asp Leu Trp 1 5 10 <210> 3845 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3845 tttaccaggg acatatccgc gactacagcc tacctggaac tgaccagcct gacttctgaa 60 gacacggctt tctattactg tgcgagagga gggagcgaca actggcacct cgatctgtgg 120 ggccgtggc 129 <210> 3846 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3846 Phe Thr Arg Asp Ile Ser Ala Thr Thr Ala Tyr Leu Glu Leu Thr Ser 1 5 10 15 Leu Thr Ser Glu Asp Thr Ala Phe Tyr Tyr Cys Ala Arg Gly Gly Ser 20 25 30 Asp Asn Trp His Leu Asp Leu Trp Gly Arg Gly 35 40 <210> 3847 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3847 tttaccagag acacatccgc gactacagcc tacatggaac tgaccagcct gaggtctgaa 60 gacacggctg tatattactg tgcgagagga gggagcgaca actggcacct cgatctgtgg 120 ggccgtggc 129 <210> 3848 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3848 Phe Thr Arg Asp Thr Ser Ala Thr Thr Ala Tyr Met Glu Leu Thr Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Ser 20 25 30 Asp Asn Trp His Leu Asp Leu Trp Gly Arg Gly 35 40 <210> 3849 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3849 tttaccagac acacatccgc gactacagcc tacatggaac tgaccagcct gaggtctgaa 60 gacacggctg tatattactg tgcgagagga gggagcgaca actggcacct cgatctgtgg 120 ggccgtggc 129 <210> 3850 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3850 Phe Thr Arg His Thr Ser Ala Thr Thr Ala Tyr Met Glu Leu Thr Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Ser 20 25 30 Asp Asn Trp His Leu Asp Leu Trp Gly Arg Gly 35 40 <210> 3851 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3851 ttaaccagac acacatccgc gactacagcc tacatggaac tgaccagcct gaggtctgaa 60 gacacggctg tatattactg tgcgagagga gggagcgaca actggcacct cgatctgtgg 120 ggccgtggc 129 <210> 3852 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3852 Leu Thr Arg His Thr Ser Ala Thr Thr Ala Tyr Met Glu Leu Thr Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Ser 20 25 30 Asp Asn Trp His Leu Asp Leu Trp Gly Arg Gly 35 40 <210> 3853 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3853 Cys Thr Arg Gly Gly Val Val Gly Val Ser Ala Pro Tyr Asp Trp 1 5 10 15 <210> 3854 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3854 gccagagaca attccaagaa cacgctgtat cttcaaatga acagcctgag agccgaggac 60 acgggcgtgt atttatgtac gagagggggt gtagtggggg ttagtgcccc ttacgactgg 120 ggcctggga 129 <210> 3855 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3855 Ala Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Gly Val Tyr Leu Cys Thr Arg Gly Gly Val Val 20 25 30 Gly Val Ser Ala Pro Tyr Asp Trp Gly Leu Gly 35 40 <210> 3856 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3856 gccagagaca attccaagaa cacgctgtat cttcaaatga acagcctgag agccgaggac 60 acgggcgtgt atttatgtac gagagggggg gtagtggggg ttagtgcccc ttacgactgg 120 ggcctggga 129 <210> 3857 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3857 gacagagaca attccaagaa cacgctgtat cttcaaatga acagcctgag agccgatgac 60 acgggcgtgt atttatgtac gagagggggt gtagtggggg ttagtgcccc ttacgactgg 120 ggcctggga 129 <210> 3858 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3858 Asp Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Asp Asp Thr Gly Val Tyr Leu Cys Thr Arg Gly Gly Val Val 20 25 30 Gly Val Ser Ala Pro Tyr Asp Trp Gly Leu Gly 35 40 <210> 3859 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3859 gacagagaca attccaagaa cacgctgtat cttcaaatga acagcctgag agccgaggac 60 acgggcgtgt atttatgtac gagagggggg gtagtggggg ttagtgcccc ttacgactgg 120 ggcctggga 129 <210> 3860 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3860 Asp Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Gly Val Tyr Leu Cys Thr Arg Gly Gly Val Val 20 25 30 Gly Val Ser Ala Pro Tyr Asp Trp Gly Leu Gly 35 40 <210> 3861 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3861 Cys Ala Arg Gln Gly Arg Gly Asn Trp Phe Asp Pro Trp 1 5 10 <210> 3862 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3862 accatatcag tagacacgtc caagaaccag ttctccctga agctgagctc tgtgaccgcc 60 gcagacacgg ccgtgtatta ctgtgcgaga cagggtagag ggaactggtt cgacccctgg 120 ggccaggga 129 <210> 3863 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3863 Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gln Gly 20 25 30 Arg Gly Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3864 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3864 accatatcag tacacacgtc caagaaccag ttctccctga agctgagctc tgtgaccgcc 60 gcagacacgg ccgtgtatta ctgtgcgaga cagggtagag ggaactggtt cgacccctgg 120 ggccaggga 129 <210> 3865 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3865 Thr Ile Ser Val His Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gln Gly 20 25 30 Arg Gly Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3866 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3866 acaatatcag tacacacgtc caagaaccag ttctccctga agctgagctc tgtgaccgcc 60 gcagacacgg ccgtgtatta ctgtgcgaga cagggtagag ggaactggtt cgacccctgg 120 ggccaggga 129 <210> 3867 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3867 aacatatcag tagacacgtc caagaaccag ttctccctga agctgagctc tgtgaccgcc 60 gcagacacgg ccgtgtatta ctgtgcgaga cagggtagag ggaactggtt cgacccctgg 120 ggccaggga 129 <210> 3868 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3868 Asn Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gln Gly 20 25 30 Arg Gly Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 3869 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3869 Cys Ala Arg Glu Ala Val Gly Ala Thr Pro Phe Phe Asp Asp Trp 1 5 10 15 <210> 3870 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3870 tcagtagaca cgtccaagaa ccagttctcc ctgaagctga gctctgtgtc cgccgcggac 60 acggccgtat attattgtgc gagagaggcg gtgggagcca ctcccttttt tgacgactgg 120 ggccaggga 129 <210> 3871 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3871 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Ser Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Ala Val Gly 20 25 30 Ala Thr Pro Phe Phe Asp Asp Trp Gly Gln Gly 35 40 <210> 3872 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3872 tcagtagaca cgtccaagaa ccagttctcc ctgaagctga gctctgtggc cgccgcggac 60 acggccgtat attattgtgc gagagaggcg gtgggagcca ctcccttttt tgacgactgg 120 ggccaggga 129 <210> 3873 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3873 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Ala Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Ala Val Gly 20 25 30 Ala Thr Pro Phe Phe Asp Asp Trp Gly Gln Gly 35 40 <210> 3874 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3874 tcagtagaca cgtccaacaa ccagttctcc ctgaagctga gctctgtgtc cgccgcggac 60 acggccgtat attattgtgc gagagaggcg gtgggagcca ctcccttttt tgacgactgg 120 ggccaggga 129 <210> 3875 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3875 Ser Val Asp Thr Ser Asn Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Ser Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Ala Val Gly 20 25 30 Ala Thr Pro Phe Phe Asp Asp Trp Gly Gln Gly 35 40 <210> 3876 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3876 tcagtacaca cgtccaacaa ccagttctcc ctgaagctga gctctgtgtc cgccgcggac 60 acggccgtat attattgtgc gagagaggcg gtgggagcca ctcccttttt tgacgactgg 120 ggccaggga 129 <210> 3877 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3877 Ser Val His Thr Ser Asn Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Ser Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Ala Val Gly 20 25 30 Ala Thr Pro Phe Phe Asp Asp Trp Gly Gln Gly 35 40 <210> 3878 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3878 Cys Val Arg Val Pro Ala Ala Ala Gly Lys Gly Val Pro Gly Ile Phe 1 5 10 15 Asp Ile Trp <210> 3879 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3879 tcctcgacct cagtctacat ggagctgagg agcctgagat ctgacgacac ggccgtgtat 60 tactgtgtga gagtaccagc agcagctgga aagggcgtcc ctggtatttt tgatatttgg 120 ggccaaggg 129 <210> 3880 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3880 Ser Ser Thr Ser Val Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Val Arg Val Pro Ala Ala Ala Gly Lys Gly 20 25 30 Val Pro Gly Ile Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3881 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3881 tccacgacca cagtctacat ggagctgagg agcctgagat ctgacgacac ggccgtgtat 60 tactgtgtga gagtaccagc agcagctgga aagggcgtcc ctggtatttt tgatatttgg 120 ggccaaggg 129 <210> 3882 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3882 Ser Thr Thr Thr Val Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Val Arg Val Pro Ala Ala Ala Gly Lys Gly 20 25 30 Val Pro Gly Ile Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3883 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3883 cccacgacca cagtctacat ggagctgagg agcctgagat ctgacgacac ggccgtgtat 60 tactgtgtga gagtaccagc agcagctgga aagggcgtcc ctggtatttt tgatatttgg 120 ggccaaggg 129 <210> 3884 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3884 Pro Thr Thr Thr Val Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Val Arg Val Pro Ala Ala Ala Gly Lys Gly 20 25 30 Val Pro Gly Ile Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3885 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3885 cccacgacca aagtctacat ggagctgagg agcctgagat ctgacgacac ggccgtgtat 60 tactgtgtga gagtaccagc agcagctgga aagggcgtcc ctggtatttt tgatatttgg 120 ggccaaggg 129 <210> 3886 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3886 Pro Thr Thr Lys Val Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Val Arg Val Pro Ala Ala Ala Gly Lys Gly 20 25 30 Val Pro Gly Ile Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3887 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3887 Cys Ala Lys Asp Gly Thr Glu Trp Trp Glu Ser Leu Thr Phe Tyr Asp 1 5 10 15 Tyr Trp <210> 3888 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3888 aattccaaga acacgctgta tctgcaaatg aatagcctga gagtcgacga ctcgggtgtg 60 tactactgtg cgaaagatgg tacggagtgg tgggagtcac tcaccttcta tgactactgg 120 ggccaggga 129 <210> 3889 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3889 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Val Asp 1 5 10 15 Asp Ser Gly Val Tyr Tyr Cys Ala Lys Asp Gly Thr Glu Trp Trp Glu 20 25 30 Ser Leu Thr Phe Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3890 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3890 aattccaaga acacgctgta tctgaaaatg aatagcctga gaggcgacga ctcgggtgtg 60 tactactgtg cgaaagatgg tacggagtgg tgggagtcac tcaccttcta tgactactgg 120 ggccaggga 129 <210> 3891 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3891 Asn Ser Lys Asn Thr Leu Tyr Leu Lys Met Asn Ser Leu Arg Gly Asp 1 5 10 15 Asp Ser Gly Val Tyr Tyr Cys Ala Lys Asp Gly Thr Glu Trp Trp Glu 20 25 30 Ser Leu Thr Phe Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3892 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3892 aattccaaca acacgctgta tctgaaaatg aatagcctga gagtcgacga ctcgggtgtg 60 tactactgtg cgaaagatgg tacggagtgg tgggagtcac tcaccttcta tgactactgg 120 ggccaggga 129 <210> 3893 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3893 Asn Ser Asn Asn Thr Leu Tyr Leu Lys Met Asn Ser Leu Arg Val Asp 1 5 10 15 Asp Ser Gly Val Tyr Tyr Cys Ala Lys Asp Gly Thr Glu Trp Trp Glu 20 25 30 Ser Leu Thr Phe Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3894 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3894 aattccaaga acacgctgta tctgcaaatg aatcgcctga gagtcgacga ctcgggtgtg 60 tactactgtg cgaaagatgg tacggagtgg tgggagtcac tcaccttcta tgactactgg 120 ggccaggga 129 <210> 3895 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3895 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Arg Leu Arg Val Asp 1 5 10 15 Asp Ser Gly Val Tyr Tyr Cys Ala Lys Asp Gly Thr Glu Trp Trp Glu 20 25 30 Ser Leu Thr Phe Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3896 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3896 Cys Ala Arg Glu Gly Gly Gly Ser Ser Phe Asp Tyr Trp 1 5 10 <210> 3897 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3897 accatcaacc cggacacatc caagaaccag ttctccctgc agctgaactc tgtgactccc 60 gaggacacgg ctgtgtatta ctgtgcaaga gaggggggtg ggagttcgtt tgactactgg 120 ggccaggga 129 <210> 3898 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3898 Thr Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly 20 25 30 Gly Gly Ser Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3899 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3899 accatcaacc cggacacatc caagaaccag ttctccctgc agctgaactc tgtgactccc 60 aaggacacgg ctgtgtatta ctgtgcaaga gaggggggtg ggagttcgtt tgactactgg 120 ggccaggga 129 <210> 3900 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3900 Thr Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Lys Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly 20 25 30 Gly Gly Ser Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3901 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3901 accatcaacc cgcacacatc caagaaccag ttctccctgc agctgaactc tgtgactccc 60 gaggacacgg ctgtgtatta ctgtgcaaga gaggggggtg ggagttcgtt tgactactgg 120 ggccaggga 129 <210> 3902 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3902 Thr Ile Asn Pro His Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly 20 25 30 Gly Gly Ser Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3903 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3903 accatcaacc cgcacacatc caagaaccag ttctccctgc agctgaactc tgtgactccc 60 aaggacacgg ctgtgtatta ctgtgcaaga gaggggggtg ggagttcgtt tgactactgg 120 ggccaggga 129 <210> 3904 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3904 Thr Ile Asn Pro His Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Lys Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly 20 25 30 Gly Gly Ser Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3905 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3905 Cys Ala Ser Gly Tyr Ser Ser Ser Trp Tyr Asp Tyr Trp 1 5 10 <210> 3906 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3906 accatctcca tacacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgagc gggtatagca gcagctggta cgattactgg 120 ggccaggga 129 <210> 3907 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3907 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly Tyr 20 25 30 Ser Ser Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3908 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3908 accatctcca gagacaattc caagaacacg ctgtatcttc aaatgaacag cctgggagcc 60 gaggacacgg ccgtgtatta ctgtgcgagc gggtatagca gcagctggta cgattactgg 120 ggccaggga 129 <210> 3909 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3909 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Gly Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly Tyr 20 25 30 Ser Ser Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3910 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3910 accatctcca gagacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgagc gggtatagca gcagctggta cgattactgg 120 ggccaggga 129 <210> 3911 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3911 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly Tyr 20 25 30 Ser Ser Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3912 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3912 accatctcca gacacaattc caacaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgagc gggtatagca gcagctggta cgattactgg 120 ggccaggga 129 <210> 3913 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3913 Thr Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly Tyr 20 25 30 Ser Ser Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 3914 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3914 Cys Ala Arg Asp Ser Ser Ser Trp Tyr Tyr Glu Ser Pro Asp Phe Tyr 1 5 10 15 Tyr Tyr Tyr Gly Met Asp Val Trp 20 <210> 3915 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3915 tatcttcaaa tgaacagcct gagagccgag gacacggccg tgtattactg tgcgagagat 60 agcagcagct ggtactatga atccccggac ttctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3916 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3916 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Asp Ser Ser Ser Trp Tyr Tyr Glu Ser Pro Asp Phe Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3917 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3917 tatattcaaa tgaacagcct gagagccgag gacacggccg tgtattactg tgcgagagat 60 agcagcagct ggtactatga atccccggac ttctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3918 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3918 Tyr Ile Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Asp Ser Ser Ser Trp Tyr Tyr Glu Ser Pro Asp Phe Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3919 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3919 tatattcaaa tcaacagcct gagagccgag gacacggccg tgtattactg tgcgagagat 60 agcagcagct ggtactatga atccccggac ttctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3920 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3920 Tyr Ile Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Asp Ser Ser Ser Trp Tyr Tyr Glu Ser Pro Asp Phe Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3921 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3921 tatattaaaa tgaacagcct gagagccgag gacacggccg tgtattactg tgcgagagat 60 agcagcagct ggtactatga atccccggac ttctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3922 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3922 Tyr Ile Lys Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Asp Ser Ser Ser Trp Tyr Tyr Glu Ser Pro Asp Phe Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3923 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3923 Cys Ala Arg Gly Ser Gly Ser Ala Gly Tyr Phe Asp Tyr Trp 1 5 10 <210> 3924 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3924 atctccatac acaattccaa gaacacactg tatcttcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagga agtggttcgg ccggatactt tgactactgg 120 ggccaagga 129 <210> 3925 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3925 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Ser Gly 20 25 30 Ser Ala Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3926 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3926 atctccagag acaattccaa gaacacactg tatcttcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagga agtggttcgg ccggatactt tgactactgg 120 ggccaagga 129 <210> 3927 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3927 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Ser Gly 20 25 30 Ser Ala Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3928 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3928 atctccagac acaattccaa caacacactg tatcttcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagga agtggttcgg ccggatactt tgactactgg 120 ggccaagga 129 <210> 3929 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3929 Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Ser Gly 20 25 30 Ser Ala Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3930 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3930 atctccacag acaattccaa caacacactg tatcttcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagga agtggttcgg ccggatactt tgactactgg 120 ggccaagga 129 <210> 3931 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3931 Ile Ser Thr Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Ser Gly 20 25 30 Ser Ala Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3932 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3932 Cys Ala Lys Glu Phe Arg Val Arg Gly Phe Gly Glu Val Pro Arg Leu 1 5 10 15 Asp Tyr Trp <210> 3933 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3933 tcctggggga cgctgtttct gcaaatgagt agcctgagag tcgacgactc ggctatttac 60 tactgtgcga aagaatttag ggtgaggggg ttcggggagg tcccccgatt ggactactgg 120 ggccaggga 129 <210> 3934 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3934 Ser Trp Gly Thr Leu Phe Leu Gln Met Ser Ser Leu Arg Val Asp Asp 1 5 10 15 Ser Ala Ile Tyr Tyr Cys Ala Lys Glu Phe Arg Val Arg Gly Phe Gly 20 25 30 Glu Val Pro Arg Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 3935 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3935 tccaggggga cgctgtttct gcaaatgagt agcctgagag tcgacgactc ggctatttac 60 tactgtgcga aagaatttag ggtgaggggg ttcggggagg tcccccgatt ggactactgg 120 ggccaggga 129 <210> 3936 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3936 Ser Arg Gly Thr Leu Phe Leu Gln Met Ser Ser Leu Arg Val Asp Asp 1 5 10 15 Ser Ala Ile Tyr Tyr Cys Ala Lys Glu Phe Arg Val Arg Gly Phe Gly 20 25 30 Glu Val Pro Arg Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 3937 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3937 tccaggggga cgctgtttct gcaaatgagt agcctgagag gcgacgactc ggctatttac 60 tactgtgcga aagaatttag ggtgaggggg ttcggggagg tcccccgatt ggactactgg 120 ggccaggga 129 <210> 3938 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3938 Ser Arg Gly Thr Leu Phe Leu Gln Met Ser Ser Leu Arg Gly Asp Asp 1 5 10 15 Ser Ala Ile Tyr Tyr Cys Ala Lys Glu Phe Arg Val Arg Gly Phe Gly 20 25 30 Glu Val Pro Arg Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 3939 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3939 tccaagaaga cgctgtttct gcaaatgaat agcctgagag gcgaggactc ggctatgtat 60 tactgtgcga aagagttcag ggtgaggggg ttcggggagg taccccgatt ggactactgg 120 ggccaggga 129 <210> 3940 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3940 Ser Lys Lys Thr Leu Phe Leu Gln Met Asn Ser Leu Arg Gly Glu Asp 1 5 10 15 Ser Ala Met Tyr Tyr Cys Ala Lys Glu Phe Arg Val Arg Gly Phe Gly 20 25 30 Glu Val Pro Arg Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 3941 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3941 Cys Ala Lys Gly Glu Trp Leu Val Asn Ser Asp Tyr Trp 1 5 10 <210> 3942 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3942 accatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgctaag ggggagtggc tggtaaatag cgactactgg 120 ggccaggga 129 <210> 3943 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3943 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Glu 20 25 30 Trp Leu Val Asn Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 3944 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3944 accatctcca tacataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgctaag ggggagtggc tggtaaatag cgactactgg 120 ggccaggga 129 <210> 3945 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3945 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Glu 20 25 30 Trp Leu Val Asn Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 3946 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3946 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgctaag ggggagtggc tggtaaatag cgactactgg 120 ggccaggga 129 <210> 3947 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3947 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Glu 20 25 30 Trp Leu Val Asn Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 3948 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3948 aacatctcca tagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgctaag ggggagtggc tggtaaatag cgactactgg 120 ggccaggga 129 <210> 3949 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3949 Asn Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Glu 20 25 30 Trp Leu Val Asn Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 3950 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3950 Cys Ala Lys Asp Gln Arg Arg Ser Gly Val Asn Val Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 3951 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3951 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatc aacggcggag tggggtcaac gtctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3952 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3952 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Gln Arg Arg Ser Gly Val Asn Val Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3953 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3953 aacacgatgt atctgcaaat gaacagcctg agagccgagt acacggccgt atattactgt 60 gcgaaagatc aacggcggag tggggtcaac gtctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3954 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3954 Asn Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Tyr Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Gln Arg Arg Ser Gly Val Asn Val Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3955 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3955 aacacgctgt atctgcaaat caacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatc aacggcggag tggggtcaac gtctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3956 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3956 Asn Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Gln Arg Arg Ser Gly Val Asn Val Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3957 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3957 aacacgctgt atctccaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatc aacggcggag tggggtcaac gtctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3958 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3958 Cys Ala Lys Glu Arg Gln Trp Leu Val Glu Pro Phe Phe Asp Tyr Trp 1 5 10 15 <210> 3959 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3959 agagacaatt ccaagaacat ggtttatctg cacatgaaca gcctgagagc cgacgacacg 60 gccgtatatt actgtgcgaa agagaggcag tggctggtag agccattttt tgactactgg 120 ggccaggga 129 <210> 3960 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3960 Arg Asp Asn Ser Lys Asn Met Val Tyr Leu His Met Asn Ser Leu Arg 1 5 10 15 Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Arg Gln Trp Leu 20 25 30 Val Glu Pro Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3961 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3961 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agagaggcag tggctggtag agccattttt tgactactgg 120 ggccaggga 129 <210> 3962 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3962 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Arg Gln Trp Leu 20 25 30 Val Glu Pro Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3963 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3963 agagacaatt ccaagaacac cctatatctg cagatgaaca gcctgagagc cgaggacacg 60 gccgtctatt actgtgcgaa agagaggcag tggctggtag agccattttt tgactactgg 120 ggccaggga 129 <210> 3964 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3964 acagacaatt ccaagaacac gctgtatctg caaatgaacc gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agagaggcag tggctggtag agccattttt tgactactgg 120 ggccaggga 129 <210> 3965 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3965 Thr Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Arg Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Arg Gln Trp Leu 20 25 30 Val Glu Pro Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 3966 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3966 Cys Ala Arg Asp Arg Arg Asp Ser Gly Tyr Asp Ile Asp Tyr Trp 1 5 10 15 <210> 3967 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3967 tccagagaca atgccaagaa ctcactgtat ctacaaatga acagcctgag agacgaggac 60 acggctctgt attattgtgc gagagataga cgtgatagtg gctacgatat agactactgg 120 ggccaggga 129 <210> 3968 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3968 Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Asp Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Arg Asp Arg Arg Asp 20 25 30 Ser Gly Tyr Asp Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 3969 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3969 tccagagaca atcccaacaa ctcactgtat ctacaaatga acagcctgag agacgaggac 60 acggctctgt attattgtgc gagagataga cgtgatagtg gctacgatat agactactgg 120 ggccaggga 129 <210> 3970 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3970 Ser Arg Asp Asn Pro Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Asp Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Arg Asp Arg Arg Asp 20 25 30 Ser Gly Tyr Asp Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 3971 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3971 tccagacaca atcccaagaa ctcactgtat ctacaaatga acagcctgag agacgaggac 60 acggctctgt attattgtgc gagagataga cgtgatagtg gctacgatat agactactgg 120 ggccaggga 129 <210> 3972 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3972 Ser Arg His Asn Pro Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Asp Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Arg Asp Arg Arg Asp 20 25 30 Ser Gly Tyr Asp Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 3973 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3973 tacagagaca atgccaagaa ctcactgtat ctacaaatca acagcctgag agacgaggac 60 acggctctgt attattgtgc gagagataga cgtgatagtg gctacgatat agactactgg 120 ggccaggga 129 <210> 3974 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3974 Tyr Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Ile Asn Ser Leu 1 5 10 15 Arg Asp Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Arg Asp Arg Arg Asp 20 25 30 Ser Gly Tyr Asp Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 3975 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3975 Cys Ala Arg Gly Tyr Asn Trp Asn Asp Trp Val Leu Gly Ala Phe Asp 1 5 10 15 Ile Trp <210> 3976 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3976 aattccaaga acacgctgta tcttcaaatg aacagcctga gagccgagga cacggccgtg 60 tattactgtg cgagagggta caactggaac gactgggtct taggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 3977 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3977 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Tyr Asn Trp Asn Asp Trp 20 25 30 Val Leu Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3978 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3978 aattccaaga acacgctgta tcttcaaatc aacagcctga gagccgagga cacggccgtg 60 tattactgtg cgagagggta caactggaac gactgggtct taggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 3979 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3979 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Tyr Asn Trp Asn Asp Trp 20 25 30 Val Leu Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3980 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3980 aattccaaca acacgatgta tcttcaaatc aacagcctga gagccgagga cacggccgtg 60 tattactgtg cgagagggta caactggaac gactgggtct taggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 3981 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3981 Asn Ser Asn Asn Thr Met Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Tyr Asn Trp Asn Asp Trp 20 25 30 Val Leu Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3982 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3982 aattccaata acacgattta tcttcaaatg aacagcctga gagccgagga cacggccgtg 60 tattactgtg cgagagggta caactggaac gactgggtct taggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 3983 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3983 Asn Ser Asn Asn Thr Ile Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Tyr Asn Trp Asn Asp Trp 20 25 30 Val Leu Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 3984 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3984 Cys Leu Arg Gly Trp Ser Thr Ala Met Asp Tyr Trp 1 5 10 <210> 3985 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3985 ttcaccatct ccagagacaa cgccaagaac acgctgtatc tgcaaatgaa cagtctgaga 60 gccgaagaca cggctctgta ttattgtcta agagggtgga gtacagctat ggattactgg 120 ggccaggga 129 <210> 3986 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3986 Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Leu Arg Gly 20 25 30 Trp Ser Thr Ala Met Asp Tyr Trp Gly Gln Gly 35 40 <210> 3987 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3987 ttcaccatct ccagacacaa cgccaagaac acgctgtatc tgcaaatgaa cagtctgaga 60 gccgaagaca cggctctgta ttattgtcta agagggtgga gtacagctat ggattactgg 120 ggccaggga 129 <210> 3988 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3988 Phe Thr Ile Ser Arg His Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Leu Arg Gly 20 25 30 Trp Ser Thr Ala Met Asp Tyr Trp Gly Gln Gly 35 40 <210> 3989 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3989 ttcaccatct ccagacacaa cgccaagaac acgctgtatc tgcaaatgaa cagtctgaga 60 gccgaacaca cggctctgta ttattgtcta agagggtgga gtacagctat ggattactgg 120 ggccaggga 129 <210> 3990 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3990 Phe Thr Ile Ser Arg His Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu His Thr Ala Leu Tyr Tyr Cys Leu Arg Gly 20 25 30 Trp Ser Thr Ala Met Asp Tyr Trp Gly Gln Gly 35 40 <210> 3991 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3991 ttcaccatct ccagacacaa ccccaagaac acgctgtatc tgcaaatgaa cagtctgaga 60 gccgaagaca cggctctgta ttattgtcta agagggtgga gtacagctat ggattactgg 120 ggccaggga 129 <210> 3992 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3992 Phe Thr Ile Ser Arg His Asn Pro Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Leu Arg Gly 20 25 30 Trp Ser Thr Ala Met Asp Tyr Trp Gly Gln Gly 35 40 <210> 3993 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3993 Cys Ala Arg Glu Pro Thr Leu Thr Met Val Arg Gly Phe Val Pro Ser 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 3994 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3994 ttggtgctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagaaccg 60 accttgacta tggttcgggg atttgttcct tcctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3995 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3995 Leu Val Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Glu Pro Thr Leu Thr Met Val Arg Gly Phe Val Pro Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3996 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3996 ttggagctga ggtgcctgag atctgacgac acggccgtgt attactgtgc gagagaaccg 60 accttgacta tggttcgggg atttgttcct tcctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3997 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3997 Leu Glu Leu Arg Cys Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Glu Pro Thr Leu Thr Met Val Arg Gly Phe Val Pro Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 3998 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3998 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagaaccg 60 accttgacta tggttcgggg atttgttcct tcctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 3999 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 3999 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Glu Pro Thr Leu Thr Met Val Arg Gly Phe Val Pro Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4000 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4000 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagaaccg 60 accttgacta tggttcgggg atttgttcct tcctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4001 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4001 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Glu Pro Thr Leu Thr Met Val Arg Gly Phe Val Pro Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4002 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4002 Cys Ala Lys Glu Gly Arg Val Val Ala Ala Thr Asp Tyr Trp 1 5 10 <210> 4003 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4003 ttctccagag acaattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagag gggcgcgtgg tagctgctac agactactgg 120 ggccaggga 129 <210> 4004 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4004 Phe Ser Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Gly Arg 20 25 30 Val Val Ala Ala Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4005 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4005 atctccagag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagag gggcgcgtgg tagctgctac agactactgg 120 ggccaggga 129 <210> 4006 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4006 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Gly Arg 20 25 30 Val Val Ala Ala Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4007 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4007 atctccagac acaattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagag gggcgcgtgg tagctgctac agactactgg 120 ggccaggga 129 <210> 4008 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4008 Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Gly Arg 20 25 30 Val Val Ala Ala Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4009 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4009 atctccacac acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagag gggcgcgtgg tagctgctac agactactgg 120 ggccaggga 129 <210> 4010 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4010 Ile Ser Thr His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Gly Arg 20 25 30 Val Val Ala Ala Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4011 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4011 Cys Ala Arg Asp Leu Glu Gly Gly Tyr Phe Asp Tyr Trp 1 5 10 <210> 4012 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4012 tacatgacca gggacacgtc cacgagcaca gtctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga gatctggagg ggggttactt tgactactgg 120 ggccaggga 129 <210> 4013 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4013 Tyr Met Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu 20 25 30 Glu Gly Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4014 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4014 accatgaccc ggcacacgtc cacgagcaca gtctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga gatctggagg ggggttactt tgactactgg 120 ggccaggga 129 <210> 4015 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4015 Thr Met Thr Arg His Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu 20 25 30 Glu Gly Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4016 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4016 accatgacca gggacacgtc cacgagcaca gtctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga gatctggagg ggggttactt tgactactgg 120 ggccaggga 129 <210> 4017 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4017 Thr Met Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu 20 25 30 Glu Gly Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4018 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4018 accatgacca ggcacacgtc cacgagcaca gtctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga gatctggagg ggggttactt tgactactgg 120 ggccaggga 129 <210> 4019 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4019 Cys Ala Arg Gly Arg Trp Leu Thr Val Pro Tyr Asp Tyr Tyr Tyr Gly 1 5 10 15 Leu Asp Val Trp 20 <210> 4020 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4020 atgaaccagt tctccctgat gctggattct ctgaccgccg cggacacggc cgtatattac 60 tgtgcgaggg ggcggtggct gacggtaccg tatgactact attacggtct ggacgtctgg 120 ggccaaggg 129 <210> 4021 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4021 Met Asn Gln Phe Ser Leu Met Leu Asp Ser Leu Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Arg Trp Leu Thr Val Pro Tyr Asp 20 25 30 Tyr Tyr Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 4022 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4022 aagaaccagt tctccctgaa gctggattct ctgaccgccg cggacgcggc cgtatattac 60 tgtgcgaggg ggcggtggct gacggtaccg tatgactact attacggtct ggacgtctgg 120 ggccaaggg 129 <210> 4023 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4023 Lys Asn Gln Phe Ser Leu Lys Leu Asp Ser Leu Thr Ala Ala Asp Ala 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Arg Trp Leu Thr Val Pro Tyr Asp 20 25 30 Tyr Tyr Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 4024 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4024 aagaaccagt tctccctgaa gctggattct ctgaccgccg cggacacggc cgtatattac 60 tgtgcgaggg ggcggtggct gacggtaccg tatgactact attacggtct ggacgtctgg 120 ggccaaggg 129 <210> 4025 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4025 Lys Asn Gln Phe Ser Leu Lys Leu Asp Ser Leu Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Arg Trp Leu Thr Val Pro Tyr Asp 20 25 30 Tyr Tyr Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 4026 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4026 aacaaccagt tctccctgac gctggattct ctgaccgccg cggacacggc cgtatattac 60 tgtgcgaggg ggcggtggct gacggtaccg tatgactact attacggtct ggacgtctgg 120 ggccaaggg 129 <210> 4027 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4027 Asn Asn Gln Phe Ser Leu Thr Leu Asp Ser Leu Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Arg Trp Leu Thr Val Pro Tyr Asp 20 25 30 Tyr Tyr Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 4028 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4028 Cys Val Arg Glu Arg Gly Pro Gly Glu Pro Cys Phe Asp Cys Trp 1 5 10 15 <210> 4029 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4029 tcaagatatc attcaaagag ctctctgtat ctgcaaatga gcagcgtgaa aaccgaggac 60 acggccgtct attactgtgt tagagagagg ggaccggggg agccgtgctt tgactgctgg 120 ggccaggga 129 <210> 4030 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4030 Ser Arg Tyr His Ser Lys Ser Ser Leu Tyr Leu Gln Met Ser Ser Val 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Glu Arg Gly Pro 20 25 30 Gly Glu Pro Cys Phe Asp Cys Trp Gly Gln Gly 35 40 <210> 4031 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4031 tcaagagatt attcaaagag ctctctgtat ctgcaaatga gcagcgtgaa aaccgaggac 60 acggccgtct attactgtgt tagagagagg ggaccggggg agccgtgctt tgactgctgg 120 ggccaggga 129 <210> 4032 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4032 Ser Arg Asp Tyr Ser Lys Ser Ser Leu Tyr Leu Gln Met Ser Ser Val 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Glu Arg Gly Pro 20 25 30 Gly Glu Pro Cys Phe Asp Cys Trp Gly Gln Gly 35 40 <210> 4033 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4033 tcaagagatg attcaaagag ctctctgtat ctgcaaatga gcagcgtgaa aaccgaggac 60 acggccgtct attactgtgt tagagagagg ggaccggggg agccgtgctt tgactgctgg 120 ggccaggga 129 <210> 4034 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4034 Ser Arg Asp Asp Ser Lys Ser Ser Leu Tyr Leu Gln Met Ser Ser Val 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Glu Arg Gly Pro 20 25 30 Gly Glu Pro Cys Phe Asp Cys Trp Gly Gln Gly 35 40 <210> 4035 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4035 tcaagagatc attcaaagag ctctctgtat ctgcaaatga gcagcgtgaa aaccgaggac 60 acggccgtct attactgtgt tagagagagg ggaccggggg agccgtgctt tgactgctgg 120 ggccaggga 129 <210> 4036 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4036 Ser Arg Asp His Ser Lys Ser Ser Leu Tyr Leu Gln Met Ser Ser Val 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Glu Arg Gly Pro 20 25 30 Gly Glu Pro Cys Phe Asp Cys Trp Gly Gln Gly 35 40 <210> 4037 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4037 Cys Ala Lys Glu Phe Arg Val Arg Gly Cys Gly Glu Val Pro Arg Leu 1 5 10 15 Asp Tyr Trp <210> 4038 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4038 tcctggggga cgctgtttct ccaaatgagt agcctgagag gcgacgactc ggctatttac 60 tactgtgcga aagaatttag ggtgaggggg tgcggggagg tcccccgatt ggactactgg 120 ggccaggga 129 <210> 4039 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4039 Ser Trp Gly Thr Leu Phe Leu Gln Met Ser Ser Leu Arg Gly Asp Asp 1 5 10 15 Ser Ala Ile Tyr Tyr Cys Ala Lys Glu Phe Arg Val Arg Gly Cys Gly 20 25 30 Glu Val Pro Arg Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4040 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4040 tccaggggga cgctgtttct gcaaatgagt agcctgagag tcgacgactc ggctatttac 60 tactgtgcga aagaatttag ggtgaggggg tgcggggagg tcccccgatt ggactactgg 120 ggccaggga 129 <210> 4041 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4041 Ser Arg Gly Thr Leu Phe Leu Gln Met Ser Ser Leu Arg Val Asp Asp 1 5 10 15 Ser Ala Ile Tyr Tyr Cys Ala Lys Glu Phe Arg Val Arg Gly Cys Gly 20 25 30 Glu Val Pro Arg Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4042 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4042 tccaagaaga cgctgtttct gcaaatgaat agcctgagag gcgaggactc ggctatgtat 60 tactgtgcga aagagttccg ggtgaggggg tgcggggagg taccccgatt ggactactgg 120 ggccaggga 129 <210> 4043 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4043 Ser Lys Lys Thr Leu Phe Leu Gln Met Asn Ser Leu Arg Gly Glu Asp 1 5 10 15 Ser Ala Met Tyr Tyr Cys Ala Lys Glu Phe Arg Val Arg Gly Cys Gly 20 25 30 Glu Val Pro Arg Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4044 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4044 tccaagaaga cgctgtttct gcaaatgaat agcctgagag gcgaggactc ggctatgtat 60 tactgtgcga aagagttcag ggtgaggggg tgcggggagg taccccgatt ggactactgg 120 ggccaggga 129 <210> 4045 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4045 Cys Thr Ser Arg Arg Ile Pro Asp Pro Asp Tyr Trp 1 5 10 <210> 4046 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4046 ttcaccatct ccatagatta ttcaaagaac acggcgtatc tgcaaatgaa cagcctgaaa 60 accgaggaca cggccgtgta ttactgtact agccgacgga tacctgaccc ggactactgg 120 ggccaggga 129 <210> 4047 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4047 Phe Thr Ile Ser Ile Asp Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Arg 20 25 30 Arg Ile Pro Asp Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4048 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4048 ttcaccatct ccagatatga ttcaaagaac acggcgtatc tgcaaatgaa cagcctgaaa 60 cccgaggaca cggccgtgta ttactgtact agccgacgga tacctgaccc ggactactgg 120 ggccaggga 129 <210> 4049 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4049 Phe Thr Ile Ser Arg Tyr Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Pro Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Arg 20 25 30 Arg Ile Pro Asp Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4050 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4050 ttcaccatct ccagatatga ttcaaagaac acggcgtatc tgaaaatgaa cagcctgaaa 60 accgaggaca cggccgtgta ttactgtact agccgacgga tacctgaccc ggactactgg 120 ggccaggga 129 <210> 4051 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4051 Phe Thr Ile Ser Arg Tyr Asp Ser Lys Asn Thr Ala Tyr Leu Lys Met 1 5 10 15 Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Arg 20 25 30 Arg Ile Pro Asp Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4052 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4052 ttcaccatct ccagagatga ttcaaagaac acggcgtatc tgcaaatgaa cagcctgaaa 60 accgaggaca cggccgtgta ttactgtact agccgacgga tacctgaccc ggactactgg 120 ggccaggga 129 <210> 4053 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4053 Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Arg 20 25 30 Arg Ile Pro Asp Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4054 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4054 Cys Ala Arg Ala Arg Ser Gly Tyr Tyr Ile Asp Tyr Trp 1 5 10 <210> 4055 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4055 tccatctcca tagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggggacacgg ctgtgtatta ctgtgcaaga gcgcggagtg gttattacat tgactactgg 120 ggccaggga 129 <210> 4056 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4056 Ser Ile Ser Ile Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Arg 20 25 30 Ser Gly Tyr Tyr Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4057 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4057 accatctcca gagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggggacacgg ctgtgtatta ctgtgcaaga gcgcggagtg gttattacat tgactactgg 120 ggccaggga 129 <210> 4058 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4058 Thr Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Arg 20 25 30 Ser Gly Tyr Tyr Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4059 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4059 aacatctcca tagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggggacacgg ctgtgtatta ctgtgcaaga gcgcggagtg gttattacat tgactactgg 120 ggccaggga 129 <210> 4060 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4060 Asn Ile Ser Ile Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Arg 20 25 30 Ser Gly Tyr Tyr Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4061 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4061 aacatctcca gagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggtgacacgg ctgtgtatta ctgtgcaaga gcgcggagtg gttattacat tgactactgg 120 ggccaggga 129 <210> 4062 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4062 Asn Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Arg 20 25 30 Ser Gly Tyr Tyr Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4063 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4063 Cys Ala Arg Glu Ser Asp Ala Val Gly Ala Thr Val Thr Asn Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 4064 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4064 tcgctgtatc ttcaaatgac cagcctgaga gccgaggaca cggccgtgta ttactgtgcg 60 agagagtccg acgccgtggg ggctacggtt acaaattact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4065 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4065 Ser Leu Tyr Leu Gln Met Thr Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Glu Ser Asp Ala Val Gly Ala Thr Val Thr Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4066 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4066 tcgatgtatc ttcaaatgaa cagcctgaga gccgaggaca cggccgtgta ttactgtgcg 60 agagagtccg acgccgtggg ggctacggtt acaaattact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4067 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4067 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Glu Ser Asp Ala Val Gly Ala Thr Val Thr Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4068 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4068 acgctgtatc ttcaaatgaa cagcctgaga gccgaggaca cggccgtgta ttactgtgcg 60 agagagtccg acgccgtggg ggctacggtt acaaattact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4069 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4069 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Glu Ser Asp Ala Val Gly Ala Thr Val Thr Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4070 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4070 acgatgtatc ttcaaatcaa cagcctgaga gccgaggaca cggccgtgta ttactgtgcg 60 agagagtccg acgccgtggg ggctacggtt acaaattact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4071 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4071 Thr Met Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Glu Ser Asp Ala Val Gly Ala Thr Val Thr Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4072 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4072 Cys Ala Lys Val Val Gly Ile Leu Thr Gly Tyr Phe Asp Trp 1 5 10 <210> 4073 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4073 atctccatat acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagtt gttggtattt tgactggtta tttcgactgg 120 ggccaggga 129 <210> 4074 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4074 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Val Gly 20 25 30 Ile Leu Thr Gly Tyr Phe Asp Trp Gly Gln Gly 35 40 <210> 4075 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4075 atctccatac acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagtt gttggtattt tgactggtta tttcgactgg 120 ggccaggga 129 <210> 4076 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4076 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Val Gly 20 25 30 Ile Leu Thr Gly Tyr Phe Asp Trp Gly Gln Gly 35 40 <210> 4077 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4077 atctccagag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagtt gttggtattt tgactggtta tttcgactgg 120 ggccaggga 129 <210> 4078 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4078 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Val Gly 20 25 30 Ile Leu Thr Gly Tyr Phe Asp Trp Gly Gln Gly 35 40 <210> 4079 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4079 atctccagac acaattccaa caacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagtt gttggtattt tgactggtta tttcgactgg 120 ggccaggga 129 <210> 4080 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4080 Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Val Gly 20 25 30 Ile Leu Thr Gly Tyr Phe Asp Trp Gly Gln Gly 35 40 <210> 4081 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4081 Cys Ala Lys Asp Arg Leu Arg Ser Ser Asp Tyr Trp 1 5 10 <210> 4082 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4082 ttcaccatct ccagagacaa ttccaagagc actctatatc tgcaaatgag cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagatcgcc tacggtcctc agactactgg 120 ggcccggga 129 <210> 4083 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4083 Phe Thr Ile Ser Arg Asp Asn Ser Lys Ser Thr Leu Tyr Leu Gln Met 1 5 10 15 Ser Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp 20 25 30 Arg Leu Arg Ser Ser Asp Tyr Trp Gly Pro Gly 35 40 <210> 4084 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4084 ttcaccatct ccagagacaa ttccaagaac acactatatc tgcaaatgag cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagatcgcc tacggtcctc agactactgg 120 ggccaggga 129 <210> 4085 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4085 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Ser Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp 20 25 30 Arg Leu Arg Ser Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 4086 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4086 ttcaccatct ccagacacaa ttccaagagc actctatatc tgcaaatgag cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagatcgcc tacggtcctc agactactgg 120 ggcccggga 129 <210> 4087 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4087 Phe Thr Ile Ser Arg His Asn Ser Lys Ser Thr Leu Tyr Leu Gln Met 1 5 10 15 Ser Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp 20 25 30 Arg Leu Arg Ser Ser Asp Tyr Trp Gly Pro Gly 35 40 <210> 4088 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4088 ttcaccatct ccagacacaa ttccaagaac acaatatatc tgcaaatgag cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagatcgcc tacggtcctc agactactgg 120 ggccaggga 129 <210> 4089 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4089 Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Ile Tyr Leu Gln Met 1 5 10 15 Ser Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp 20 25 30 Arg Leu Arg Ser Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 4090 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4090 Cys Ala Lys Gly Pro Leu Val Gly Trp Tyr Phe Asp Leu Trp 1 5 10 <210> 4091 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4091 ttctccagat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagga cctctcgtag gctggtactt cgatctctgg 120 ggccgtggc 129 <210> 4092 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4092 Phe Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Pro Leu 20 25 30 Val Gly Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4093 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4093 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagga cctctcgtag gctggtactt cgatctctgg 120 ggccgtggc 129 <210> 4094 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4094 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Pro Leu 20 25 30 Val Gly Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4095 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4095 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagga cctctcgtag gctggtactt cgatctctgg 120 ggccgtggc 129 <210> 4096 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4096 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Pro Leu 20 25 30 Val Gly Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4097 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4097 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagga cctctcgtag gctggtactt cgatctctgg 120 ggccgtggc 129 <210> 4098 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4098 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Pro Leu 20 25 30 Val Gly Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4099 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4099 Cys Ala Asn Ser Gln Asp Tyr Asp Ser Ser Gly Tyr Tyr Pro Asp Tyr 1 5 10 15 Trp <210> 4100 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4100 tacaattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaactc gcaggactat gatagtagtg gttattaccc cgactactgg 120 ggccaggga 129 <210> 4101 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4101 Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Asn Ser Gln Asp Tyr Asp Ser 20 25 30 Ser Gly Tyr Tyr Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4102 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4102 gacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaactc gcaggactat gatagtagtg gttattaccc cgactactgg 120 ggccaggga 129 <210> 4103 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4103 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Asn Ser Gln Asp Tyr Asp Ser 20 25 30 Ser Gly Tyr Tyr Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4104 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4104 gacaatacca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaactc gcaggactat gatagtagtg gttattaccc cgactactgg 120 ggccaggga 129 <210> 4105 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4105 Asp Asn Thr Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Asn Ser Gln Asp Tyr Asp Ser 20 25 30 Ser Gly Tyr Tyr Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4106 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4106 gaaaattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaactc gcaggactat gatagtagtg gttattaccc cgactactgg 120 ggccaggga 129 <210> 4107 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4107 Glu Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Asn Ser Gln Asp Tyr Asp Ser 20 25 30 Ser Gly Tyr Tyr Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4108 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4108 Cys Ala Lys Thr Arg His Tyr Gly Asp Tyr Trp Tyr Phe Asp Leu Trp 1 5 10 15 <210> 4109 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4109 ttagataatt ccaagaacac gctgcatctg caaatgaaca gcctgagagc cgacgacacg 60 gccgtatatt actgtgcgaa aactagacac tacggtgact actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4110 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4110 Leu Asp Asn Ser Lys Asn Thr Leu His Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr Arg His Tyr Gly 20 25 30 Asp Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4111 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4111 atatataatt ccaagaacac gctgcatctg caaatgaaca gcctgagagc cgacgacacg 60 gccgtatatt actgtgcgaa aactagacac tacggtgact actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4112 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4112 Ile Tyr Asn Ser Lys Asn Thr Leu His Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr Arg His Tyr Gly 20 25 30 Asp Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4113 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4113 atagataatt ccaacaacac gctgcatctg caaatgaaca gcctgagagc cgacgacacg 60 gccgtatatt actgtgcgaa aactagacac tacggtgact actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4114 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4114 Ile Asp Asn Ser Asn Asn Thr Leu His Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr Arg His Tyr Gly 20 25 30 Asp Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4115 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4115 agagataatt ccaagaacac gctgcatctg caaatgaaca gcctgagagc cgacgacacg 60 gccgtatatt actgtgcgaa aactagacac tacggtgact actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4116 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4116 Arg Asp Asn Ser Lys Asn Thr Leu His Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Lys Thr Arg His Tyr Gly 20 25 30 Asp Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4117 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4117 Cys Ala Lys Asp Arg Arg Phe Gly Glu Phe Asp Pro Trp 1 5 10 <210> 4118 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4118 accatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gatcggaggt tcggggagtt cgacccctgg 120 ggccaggga 129 <210> 4119 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4119 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg 20 25 30 Arg Phe Gly Glu Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4120 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4120 accatctcca tacataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gatcggaggt tcggggagtt cgacccctgg 120 ggccaggga 129 <210> 4121 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4121 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg 20 25 30 Arg Phe Gly Glu Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4122 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4122 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gatcggaggt tcggggagtt cgacccctgg 120 ggccaggga 129 <210> 4123 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4123 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg 20 25 30 Arg Phe Gly Glu Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4124 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4124 aacatctcca tagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gatcggaggt tcggggagtt cgacccctgg 120 ggccaggga 129 <210> 4125 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4125 Asn Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg 20 25 30 Arg Phe Gly Glu Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4126 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4126 Cys Ala Lys Gly Arg Ser Ser Ser Trp Tyr Asp Tyr Trp 1 5 10 <210> 4127 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4127 accatctcca tatacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gggcgtagca gcagctggta cgactactgg 120 ggccaggga 129 <210> 4128 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4128 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg 20 25 30 Ser Ser Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4129 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4129 accatctcca tacacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gggcgtagca gcagctggta cgactactgg 120 ggccaggga 129 <210> 4130 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4130 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg 20 25 30 Ser Ser Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4131 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4131 accatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gggcgtagca gcagctggta cgactactgg 120 ggccaggga 129 <210> 4132 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4132 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg 20 25 30 Ser Ser Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4133 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4133 accatctcca gacacaattc caacaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gggcgtagca gcagctggta cgactactgg 120 ggccaggga 129 <210> 4134 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4134 Thr Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg 20 25 30 Ser Ser Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4135 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4135 Cys Gly His Ser Ser Ser Trp Tyr Cys Leu Asp Tyr Trp 1 5 10 <210> 4136 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4136 accatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtggtcat agcagcagct ggtactgcct tgactactgg 120 ggccaggga 129 <210> 4137 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4137 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly His Ser Ser 20 25 30 Ser Trp Tyr Cys Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4138 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4138 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtggtcat agcagcagct ggtactgcct tgactactgg 120 ggccaggga 129 <210> 4139 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4139 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly His Ser Ser 20 25 30 Ser Trp Tyr Cys Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4140 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4140 accatctcca gacataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtggtcat agcagcagct ggtactgcct tgactactgg 120 ggccaggga 129 <210> 4141 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4141 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly His Ser Ser 20 25 30 Ser Trp Tyr Cys Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4142 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4142 Cys Ala Lys Asp Leu Ser Val Asn Asp Tyr Gly Glu Pro Phe Asp Ser 1 5 10 15 Trp <210> 4143 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4143 ggcaacgcca agaactccct ctttctgcaa atgaacagtc tgagagctga ggacacggcc 60 ttatattact gtgcaaaaga cttgagtgtg aatgactatg gtgaaccttt tgactcctgg 120 ggccaggga 129 <210> 4144 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4144 Gly Asn Ala Lys Asn Ser Leu Phe Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Leu Ser Val Asn Asp 20 25 30 Tyr Gly Glu Pro Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 4145 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4145 gacaacgcca agaactccct ctttctgcaa atgaacagtc tgagagctga ggacacggcc 60 ttatattact gtgcaaaaga cttgagtgtg aatgactatg gtgagccttt tgactcctgg 120 ggccaggga 129 <210> 4146 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4146 Asp Asn Ala Lys Asn Ser Leu Phe Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Leu Ser Val Asn Asp 20 25 30 Tyr Gly Glu Pro Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 4147 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4147 gacaacgcca agaactccct ctttctgcaa atgaacagtc tgagagctga ggacacggcc 60 ttatattact gtgcaaaaga cttgagtgtg aatgactatg gtgaaccttt tgactcctgg 120 ggccaggga 129 <210> 4148 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4148 Cys Ala Lys Asp Met Gly Ser Pro Ile Ala Ala Ala Gly Asn Asp Tyr 1 5 10 15 Trp <210> 4149 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4149 tataattcca agaacacgct ttatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga tatgggcagc cccatagcag cagctgggaa tgactactgg 120 ggccaggga 129 <210> 4150 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4150 Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Met Gly Ser Pro Ile 20 25 30 Ala Ala Ala Gly Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 4151 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4151 tataattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga tatgggcagc cccatagcag cagctgggaa tgactactgg 120 ggccaggga 129 <210> 4152 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4152 Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Met Gly Ser Pro Ile 20 25 30 Ala Ala Ala Gly Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 4153 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4153 gataattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga tatgggcagc cccatagcag cagctgggaa tgactactgg 120 ggccaggga 129 <210> 4154 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4154 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Met Gly Ser Pro Ile 20 25 30 Ala Ala Ala Gly Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 4155 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4155 Cys Ala Lys Gly Ser Gly Ser Tyr Tyr Thr Leu Tyr Asp Tyr Trp 1 5 10 15 <210> 4156 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4156 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggttcg gggagttatt atacccttta tgattattgg 120 ggccaggga 129 <210> 4157 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4157 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Ser Gly Ser 20 25 30 Tyr Tyr Thr Leu Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4158 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4158 tccagacata attccaacaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggttcg gggagttatt atacccttta tgattattgg 120 ggccaggga 129 <210> 4159 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4159 Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Ser Gly Ser 20 25 30 Tyr Tyr Thr Leu Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4160 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4160 tccacagata attccaacaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggttcg gggagttatt atacccttta tgattattgg 120 ggccaggga 129 <210> 4161 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4161 Ser Thr Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Ser Gly Ser 20 25 30 Tyr Tyr Thr Leu Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4162 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4162 Cys Ala Arg Gly Leu Ser Ser Ser Trp Tyr Lys Asp Trp 1 5 10 <210> 4163 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4163 accatgacca ggaacacctc cataagcaca gcgtacatgg agctgagcag tctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ggcctgagca gcagctggta taaggactgg 120 ggccaggga 129 <210> 4164 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4164 Thr Met Thr Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Leu 20 25 30 Ser Ser Ser Trp Tyr Lys Asp Trp Gly Gln Gly 35 40 <210> 4165 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4165 accatgacca gcaacacctc cataagcaca gcgtacatgg agctgagcag tctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ggcctgagca gcagctggta taaggactgg 120 ggccaggga 129 <210> 4166 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4166 Thr Met Thr Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Leu 20 25 30 Ser Ser Ser Trp Tyr Lys Asp Trp Gly Gln Gly 35 40 <210> 4167 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4167 accatgacca gcaacacctc cataagcaca gcgtacatgg agctgagcag tctgagagct 60 gaggacacgg ccgtgtatta ctgtgcgaga ggcctgagca gcagctggta taaggactgg 120 ggccaggga 129 <210> 4168 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4168 Thr Met Thr Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Leu 20 25 30 Ser Ser Ser Trp Tyr Lys Asp Trp Gly Gln Gly 35 40 <210> 4169 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4169 Cys Trp Gly Arg Ile Ala Val Ala Gly Val Asp Pro Trp 1 5 10 <210> 4170 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4170 accatctcca tagatcattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgttgggga cgtatagcag tggctggagt cgacccctgg 120 ggccaggga 129 <210> 4171 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4171 Thr Ile Ser Ile Asp His Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Trp Gly Arg Ile 20 25 30 Ala Val Ala Gly Val Asp Pro Trp Gly Gln Gly 35 40 <210> 4172 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4172 accatctcca gagattattc aaagaacacg gcgtatctgc aaatgaacag ccttaaaacc 60 gaggacacgg ccgtgtatta ctgttgggga cgtatagcag tggctggagt cgacccctgg 120 ggccaggga 129 <210> 4173 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4173 Thr Ile Ser Arg Asp Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Trp Gly Arg Ile 20 25 30 Ala Val Ala Gly Val Asp Pro Trp Gly Gln Gly 35 40 <210> 4174 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4174 accatctcca gagatgattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgttgggga cgtatagcag tggctggagt cgacccctgg 120 ggccaggga 129 <210> 4175 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4175 Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Trp Gly Arg Ile 20 25 30 Ala Val Ala Gly Val Asp Pro Trp Gly Gln Gly 35 40 <210> 4176 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4176 Cys Ala Lys Asp Phe Ile Ser Ser Ser Trp Tyr Thr Tyr Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 4177 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4177 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagatttta taagcagcag ctggtacacc tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4178 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4178 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Phe Ile Ser Ser Ser Trp Tyr Thr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4179 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4179 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagatttta taagcagcag ctggtacacc tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4180 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4180 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Phe Ile Ser Ser Ser Trp Tyr Thr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4181 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4181 acgatgtatc tgcaaatcaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagatttta taagcagcag ctggtacacc tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4182 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4182 Thr Met Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Phe Ile Ser Ser Ser Trp Tyr Thr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4183 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4183 Cys Ala Lys Gly Ala Ala Ala Gly Pro Phe Asp Tyr Trp 1 5 10 <210> 4184 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4184 tacatctcca gagacaacgc caagaactcc ctgtatctgc aaatgaacag tctgagagct 60 gaggacacgg ccttgtatta ctgtgcaaaa ggggcagcag ctggcccttt tgactactgg 120 ggccaggga 129 <210> 4185 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4185 Tyr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Gly Ala 20 25 30 Ala Ala Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4186 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4186 accatctcca gagacaacgc caagaactcc ctgtatctgc aaatgaacag tctgagagct 60 gaggacacgg ccttgtatta ctgtgcaaaa ggggcagcag ctggcccttt tgactactgg 120 ggccaggga 129 <210> 4187 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4187 Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Gly Ala 20 25 30 Ala Ala Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4188 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4188 accatcccca gagacaacgc caagaactcc ctgtatctgc aaatgaacag tctgagagct 60 gaggacacgg ccttgtatta ctgtgcaaaa ggggcagcag ctggcccttt tgactactgg 120 ggccaggga 129 <210> 4189 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4189 Thr Ile Pro Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Gly Ala 20 25 30 Ala Ala Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4190 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4190 Cys Ala Lys Leu Asp His Pro Leu Ser Met Asp Val Trp 1 5 10 <210> 4191 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4191 accatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ttagatcacc ctttaagtat ggacgtctgg 120 ggccaaggg 129 <210> 4192 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4192 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Leu Asp 20 25 30 His Pro Leu Ser Met Asp Val Trp Gly Gln Gly 35 40 <210> 4193 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4193 accatctcca tacataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ttagatcacc ctttaagtat ggacgtctgg 120 ggccaaggg 129 <210> 4194 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4194 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Leu Asp 20 25 30 His Pro Leu Ser Met Asp Val Trp Gly Gln Gly 35 40 <210> 4195 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4195 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ttagatcacc ctttaagtat ggacgtctgg 120 ggccaaggg 129 <210> 4196 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4196 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Leu Asp 20 25 30 His Pro Leu Ser Met Asp Val Trp Gly Gln Gly 35 40 <210> 4197 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4197 Cys Val Lys Ala Asp Thr Gly Gly Tyr Tyr Tyr Ala Tyr Trp 1 5 10 <210> 4198 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4198 atctccatac acaattccaa gaacacactg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgtgaaagcc gatactggtg gttattacta tgcctactgg 120 ggccaggga 129 <210> 4199 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4199 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Val Lys Ala Asp Thr 20 25 30 Gly Gly Tyr Tyr Tyr Ala Tyr Trp Gly Gln Gly 35 40 <210> 4200 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4200 atctccagag acaattccaa gaacacactg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgtgaaagcc gatactggtg gttattacta tgcctactgg 120 ggccaggga 129 <210> 4201 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4201 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Val Lys Ala Asp Thr 20 25 30 Gly Gly Tyr Tyr Tyr Ala Tyr Trp Gly Gln Gly 35 40 <210> 4202 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4202 atctccagac acaattccaa caacacactg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgtgaaagcc gatactggtg gttattacta tgcctactgg 120 ggccaggga 129 <210> 4203 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4203 Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Val Lys Ala Asp Thr 20 25 30 Gly Gly Tyr Tyr Tyr Ala Tyr Trp Gly Gln Gly 35 40 <210> 4204 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4204 Cys Ala Arg Gly Arg Gly His Trp Gly Asn Trp Tyr Phe Asp Leu Trp 1 5 10 15 <210> 4205 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4205 gtagacacgt ccaacaacca gttctccctg aagctgagct ctgtgaccgc cgcggacacg 60 actgtatttt actgtgcgag aggtcggggc cactggggga actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4206 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4206 Val Asp Thr Ser Asn Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Thr Val Phe Tyr Cys Ala Arg Gly Arg Gly His Trp 20 25 30 Gly Asn Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4207 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4207 gtagacacgt ccaagaacca gttctccctg aagctgagct ctgtgaccgc cgcggacacg 60 actgtatttt actgtgcgag aggtcggggc cactggggga actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4208 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4208 Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Thr Val Phe Tyr Cys Ala Arg Gly Arg Gly His Trp 20 25 30 Gly Asn Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4209 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4209 gtagacacgc ccaagaacca gttctccctg aagctgagct ctgtgaccgc cgcggacacg 60 actgtatttt actgtgcgag aggtcggggc cactggggga actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4210 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4210 Val Asp Thr Pro Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Thr Val Phe Tyr Cys Ala Arg Gly Arg Gly His Trp 20 25 30 Gly Asn Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4211 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4211 Cys Ala Arg Val Thr Leu Phe Val Ala Asp Leu Tyr Tyr Phe His Tyr 1 5 10 15 Trp <210> 4212 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4212 gacaaattca cgaccacagc ctacatggag ctgagcagcc tgagatctga ggacacggcc 60 gtgtattact gtgcgagagt gactttgttc gtcgctgacc tgtactactt tcactactgg 120 ggccaggga 129 <210> 4213 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4213 Asp Lys Phe Thr Thr Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Thr Leu Phe Val Ala 20 25 30 Asp Leu Tyr Tyr Phe His Tyr Trp Gly Gln Gly 35 40 <210> 4214 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4214 gacaaataca cgaccacagc ctacatggag ctgagcagcc tgagatctga ggacacggcc 60 gtgtattact gtgcgagagt gactttgttc gtcgctgacc tgtactactt tcactactgg 120 ggccaggga 129 <210> 4215 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4215 Asp Lys Tyr Thr Thr Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Thr Leu Phe Val Ala 20 25 30 Asp Leu Tyr Tyr Phe His Tyr Trp Gly Gln Gly 35 40 <210> 4216 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4216 gaaaaattca cgaccacagc ctacatggag ctgagcagcc tgagatctga ggacacggcc 60 gtgtattact gtgcgagagt gactttgttc gtcgctgacc tgtactactt tcactactgg 120 ggccaggga 129 <210> 4217 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4217 Glu Lys Phe Thr Thr Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Thr Leu Phe Val Ala 20 25 30 Asp Leu Tyr Tyr Phe His Tyr Trp Gly Gln Gly 35 40 <210> 4218 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4218 Cys Ala Arg Gly Arg Gly Asp Gly Asp Gly Gly Gly Met Asp Val Trp 1 5 10 15 <210> 4219 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4219 gtagacacgt ctaagaacct gttctccctg aagctgagct ctgtgactgc cgcggacacg 60 gccgtgtatt actgtgcgag aggaagaggc gacggtgacg gcggcggtat ggacgtctgg 120 ggccaaggg 129 <210> 4220 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4220 Val Asp Thr Ser Lys Asn Leu Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg Gly Asp Gly 20 25 30 Asp Gly Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4221 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4221 gtagacacgt ctaacaacca gttctccctg aagctgagct ctgtgactgc cgcggacacg 60 gccgtgtatt actgtgcgag aggaagaggc gacggtgacg gcggcggtat ggacgtctgg 120 ggccaaggg 129 <210> 4222 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4222 Val Asp Thr Ser Asn Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg Gly Asp Gly 20 25 30 Asp Gly Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4223 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4223 gtagacacgt ctaagaacca gttctccctg aagctgagct ctgtgactgc cgcggacacg 60 gccgtgtatt actgtgcgag aggaagaggc gacggtgacg gcggcggtat ggacgtctgg 120 ggccaaggg 129 <210> 4224 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4224 Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg Gly Asp Gly 20 25 30 Asp Gly Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4225 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4225 Cys Ala Arg Ser Pro Ser Pro Asp Tyr Phe Asp His Trp 1 5 10 <210> 4226 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4226 tccatatcaa taaacacgtc caggaatcac ttctccctga agctgagctc tgtgaccgct 60 gcggacacgg ccgtgtacta ctgtgcgaga tcccccagtc cagactactt tgaccactgg 120 ggccaggga 129 <210> 4227 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4227 Ser Ile Ser Ile Asn Thr Ser Arg Asn His Phe Ser Leu Lys Leu Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ser Pro 20 25 30 Ser Pro Asp Tyr Phe Asp His Trp Gly Gln Gly 35 40 <210> 4228 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4228 tcaatatcaa taaccacgtc caggaatcac ttctccctga agctgagctc tgtgaccgct 60 gcggacacgg ccgtgtacta ctgtgcgaga tcccccagtc cagactactt tgaccactgg 120 ggccaggga 129 <210> 4229 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4229 Ser Ile Ser Ile Thr Thr Ser Arg Asn His Phe Ser Leu Lys Leu Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ser Pro 20 25 30 Ser Pro Asp Tyr Phe Asp His Trp Gly Gln Gly 35 40 <210> 4230 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4230 tcaatatcaa aaaacacgtc caggaatcac ttctccctga agctgagctc tgtgaccgct 60 gcggacacgg ccgtgtacta ctgtgcgaga tcccccagtc cagactactt tgaccactgg 120 ggccaggga 129 <210> 4231 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4231 Ser Ile Ser Lys Asn Thr Ser Arg Asn His Phe Ser Leu Lys Leu Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ser Pro 20 25 30 Ser Pro Asp Tyr Phe Asp His Trp Gly Gln Gly 35 40 <210> 4232 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4232 Cys Val Arg Asp Asn Trp Gly Leu Asp Cys Trp 1 5 10 <210> 4233 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4233 agattcacca tctcaagata tgattcaaag aactcactgt atctacaaat gaacagcctg 60 aaaaccgaag acacggccgt gtattactgt gttagagaca actgggggct tgactgctgg 120 ggccaggga 129 <210> 4234 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4234 Arg Phe Thr Ile Ser Arg Tyr Asp Ser Lys Asn Ser Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg 20 25 30 Asp Asn Trp Gly Leu Asp Cys Trp Gly Gln Gly 35 40 <210> 4235 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4235 agattcacca tctcaagaga tgattcaaag aactcactgt atctacaaat gaacagcctt 60 aaaaccgaag acacggccgt gtattactgt gttagagaca actgggggct tgactgctgg 120 ggccaggga 129 <210> 4236 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4236 Arg Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Ser Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg 20 25 30 Asp Asn Trp Gly Leu Asp Cys Trp Gly Gln Gly 35 40 <210> 4237 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4237 agattcacca tctcaagaga tgattcaaag aactcactgt atctacaaat gaacagcctg 60 aaaaccgaag acacggccgt gtattactgt gttagagaca actgggggct tgactgctgg 120 ggccaggga 129 <210> 4238 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4238 Cys Ala Arg Pro Gly Ser Ser Gly Trp Gln Gly Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 4239 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4239 tgggacacgt ccacgagcac tgtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag accgggaagt agtggctggc agggctactt tgactactgg 120 ggccaggga 129 <210> 4240 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4240 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Pro Gly Ser Ser Gly 20 25 30 Trp Gln Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4241 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4241 tgggacacgc ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag accgggaagt agtggctggc agggctactt tgactactgg 120 ggccaggga 129 <210> 4242 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4242 Trp Asp Thr Pro Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Pro Gly Ser Ser Gly 20 25 30 Trp Gln Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4243 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4243 agggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag accgggaagt agtggctggc agggctactt tgactactgg 120 ggccaggga 129 <210> 4244 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4244 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Pro Gly Ser Ser Gly 20 25 30 Trp Gln Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4245 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4245 Cys Ala Lys Asp Pro Ser Ser Ser Trp Ser Phe Gly Ile Asp Tyr Trp 1 5 10 15 <210> 4246 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4246 agagacaatt ccaagaacac gctgtatctg caaatgagca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatccgagc agcagctggt ccttcgggat tgactactgg 120 ggccaggga 129 <210> 4247 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4247 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Ser Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Ser Ser Ser 20 25 30 Trp Ser Phe Gly Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4248 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4248 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatccgagc agcagctggt ctttcgggat tgactactgg 120 ggccaggga 129 <210> 4249 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4249 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Ser Ser Ser 20 25 30 Trp Ser Phe Gly Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4250 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4250 agagacaatt ccaacaacac gctgtatctg caaatgaacc gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatccgagc agcagctggt ctttcgggat tgactactgg 120 ggccaggga 129 <210> 4251 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4251 Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Arg Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Ser Ser Ser 20 25 30 Trp Ser Phe Gly Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4252 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4252 Cys Ala Lys Gly Gly His Gly Ser Gly Asn Asp Tyr Phe Asp Ser Trp 1 5 10 15 <210> 4253 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4253 agatataatt ccaagaacac gctgtatctg caaatgaacc gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agggggccat ggttcgggga acgactactt tgactcctgg 120 ggccaggga 129 <210> 4254 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4254 Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Arg Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly His Gly Ser 20 25 30 Gly Asn Asp Tyr Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 4255 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4255 agatataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agggggccat ggttcgggga acgactactt tgactcctgg 120 ggccaggga 129 <210> 4256 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4256 Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly His Gly Ser 20 25 30 Gly Asn Asp Tyr Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 4257 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4257 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agggggccat ggttcgggga acgactactt tgactcctgg 120 ggccaggga 129 <210> 4258 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4258 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly His Gly Ser 20 25 30 Gly Asn Asp Tyr Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 4259 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4259 Cys Ala Arg Thr Arg Met Ser Gly Phe Val Leu Phe Asp Tyr Trp 1 5 10 15 <210> 4260 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4260 ctccaaggac acctccaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acggacccgg atgtccgggt tcgtcctctt tgactactgg 120 ggccaggga 129 <210> 4261 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4261 Leu Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Thr Arg Met Ser 20 25 30 Gly Phe Val Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4262 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4262 tccaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acggacccgg atgtccgggt tcgtcctctt tgactactgg 120 ggccaggga 129 <210> 4263 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4263 Ser Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Thr Arg Met Ser 20 25 30 Gly Phe Val Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4264 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4264 tacaaggaca cctccaaaat ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acggacccgg atgtccgggt tcgtcctctt tgactactgg 120 ggccaggga 129 <210> 4265 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4265 Tyr Lys Asp Thr Ser Lys Ile Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Thr Arg Met Ser 20 25 30 Gly Phe Val Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4266 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4266 Cys Ala Arg Ala Lys Arg Ala Thr Tyr Gly Gly Asn Gly Arg Tyr Ala 1 5 10 15 Phe Asp Ile Trp 20 <210> 4267 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4267 gcgagcaccg cctacatggc gctgagcagc ctgagatctg aagacacggc tgtgtattac 60 tgtgcgagag ccaaacgcgc cacttacggt ggtaacggcc gctatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4268 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4268 Ala Ser Thr Ala Tyr Met Ala Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Ala Lys Arg Ala Thr Tyr Gly Gly Asn 20 25 30 Gly Arg Tyr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4269 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4269 gcgagcacag cctacatgga gctgagcagc ctgagatctg aagacacggc tgtgtattac 60 tgtgcgagag ccaaacgcgc cacttacggt ggtaacggcc gctatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4270 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4270 Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Ala Lys Arg Ala Thr Tyr Gly Gly Asn 20 25 30 Gly Arg Tyr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4271 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4271 gcctgcacag cctacatgga gctgagcagc ctgagatctg aagacacggc tgtgtattac 60 tgtgcgagag ccaaacgcgc cacttacggt ggtaacggcc gctatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4272 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4272 Ala Cys Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Ala Lys Arg Ala Thr Tyr Gly Gly Asn 20 25 30 Gly Arg Tyr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4273 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4273 Cys Ala Lys Asp Arg Tyr Ser Gly Thr Tyr Asp Tyr Trp 1 5 10 <210> 4274 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4274 accatctcca tacacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaag gaccggtata gtgggaccta tgactactgg 120 ggccaggga 129 <210> 4275 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4275 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg 20 25 30 Tyr Ser Gly Thr Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4276 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4276 accatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaag gaccggtata gtgggaccta tgactactgg 120 ggccaggga 129 <210> 4277 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4277 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg 20 25 30 Tyr Ser Gly Thr Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4278 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4278 accatctcca gacacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaag gaccggtata gtgggaccta tgactactgg 120 ggccaggga 129 <210> 4279 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4279 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg 20 25 30 Tyr Ser Gly Thr Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4280 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4280 Cys Ala Arg Asp Pro Ser Thr Asp Thr Ile Phe Gly Pro His Gly Lys 1 5 10 15 Gly Trp Phe Asp Pro Trp 20 <210> 4281 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4281 acagcctact tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agagatccat cgaccgatac gatttttgga ccccacggga agggctggtt cgacccctgg 120 ggccaggga 129 <210> 4282 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4282 Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Pro Ser Thr Asp Thr Ile Phe Gly Pro His 20 25 30 Gly Lys Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4283 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4283 acagcctaca tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agagatccat cgaccgatac gatttttgga ccccacggga agggctggtt cgacccctgg 120 ggccaggga 129 <210> 4284 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4284 Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Pro Ser Thr Asp Thr Ile Phe Gly Pro His 20 25 30 Gly Lys Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4285 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4285 aaagcctaca tggcgctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agagatccat cgaccgatac gatttttgga ccccacggga agggctggtt cgacccctgg 120 ggccaggga 129 <210> 4286 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4286 Lys Ala Tyr Met Ala Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Pro Ser Thr Asp Thr Ile Phe Gly Pro His 20 25 30 Gly Lys Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4287 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4287 Cys Ala Ser Gly Glu Gly Gly Pro Pro Asp Tyr Trp 1 5 10 <210> 4288 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4288 gtcacgatta ccgcggacaa atccacgagc acagcctaca tggagctgag cagcctgaga 60 tctgaggaca cggccgtgta ttactgtgcg agtggtgaag gggggcctcc tgactactgg 120 ggccaggga 129 <210> 4289 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4289 Val Thr Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu 1 5 10 15 Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly 20 25 30 Glu Gly Gly Pro Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4290 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4290 gtcacgatta ccgcgcacaa atccacgagc acagcctaca tggagctgag cagcctgaga 60 tctgaggaca cggccgtgta ttactgtgcg agtggtgaag gggggcctcc tgactactgg 120 ggccaggga 129 <210> 4291 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4291 Val Thr Ile Thr Ala His Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu 1 5 10 15 Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly 20 25 30 Glu Gly Gly Pro Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4292 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4292 gtcacgatta ccgcgcacaa aaccacgagc acagcctaca tggagctgag cagcctgaga 60 tctgaggaca cggccgtgta ttactgtgcg agtggtgaag gggggcctcc tgactactgg 120 ggccaggga 129 <210> 4293 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4293 Val Thr Ile Thr Ala His Lys Thr Thr Ser Thr Ala Tyr Met Glu Leu 1 5 10 15 Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly 20 25 30 Glu Gly Gly Pro Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4294 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4294 Cys Ala Arg Glu Asn Ala Pro Phe Asp Tyr Trp 1 5 10 <210> 4295 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4295 cggttcacca tctccagata taattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgagagaaa atgccccatt tgactactgg 120 ggccaggga 129 <210> 4296 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4296 Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Glu Asn Ala Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4297 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4297 cggttcacca tctccagata taattccaag aacacgctgt atctgcaaat caacagcctg 60 agagccgagg acacggccgt atattactgt gcgagagaaa atgccccatt tgactactgg 120 ggccaggga 129 <210> 4298 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4298 Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Glu Asn Ala Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4299 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4299 cggttcacca tctccagaga taattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgagagaaa atgccccatt tgactactgg 120 ggccaggga 129 <210> 4300 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4300 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Glu Asn Ala Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4301 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4301 Cys Ala Arg Asp His Gly Ser Gly Ser Tyr Trp Gly Asn Ala Phe Asp 1 5 10 15 Ile Trp <210> 4302 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4302 acgtccacgt gcacagtcta cttggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagagacca tggttcgggg agttattggg gcaatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4303 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4303 Thr Ser Thr Cys Thr Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp His Gly Ser Gly Ser Tyr 20 25 30 Trp Gly Asn Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4304 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4304 acgtccacgt gcacagtcta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagagacca tggttcgggg agttattggg gcaatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4305 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4305 Thr Ser Thr Cys Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp His Gly Ser Gly Ser Tyr 20 25 30 Trp Gly Asn Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4306 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4306 acgtccacga gcacagtcta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagagacca tggttcgggg agttattggg gcaatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4307 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4307 Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp His Gly Ser Gly Ser Tyr 20 25 30 Trp Gly Asn Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4308 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4308 Cys Ala His Arg Asn Thr Trp Ile Gln Leu Trp Gly Gly Trp Phe Asp 1 5 10 15 Pro Trp <210> 4309 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4309 tcctccaaaa acctggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacagaaa tacgtggata cagctatggg gggggtggtt cgacccctgg 120 ggccaggga 129 <210> 4310 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4310 Ser Ser Lys Asn Leu Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Asn Thr Trp Ile Gln Leu 20 25 30 Trp Gly Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4311 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4311 acctccaaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacagaaa tacgtggata cagctatggg gggggtggtt cgacccctgg 120 ggccaggga 129 <210> 4312 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4312 Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Asn Thr Trp Ile Gln Leu 20 25 30 Trp Gly Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4313 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4313 cacctccaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacagaaa tacgtggata cagctatggg gggggtggtt cgacccctgg 120 ggccaggga 129 <210> 4314 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4314 His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Asn Thr Trp Ile Gln Leu 20 25 30 Trp Gly Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4315 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4315 Cys Ala His Ile Arg Pro Gly Ile Trp Gly Met Asp Val Trp 1 5 10 <210> 4316 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4316 catcaccaag gacacctcca aaaccaggtg gtccttacaa tgaccaacat ggaccctgtg 60 gacacagcca catattactg tgcacacata cgtccgggta tctggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4317 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4317 His His Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ile Arg Pro 20 25 30 Gly Ile Trp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4318 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4318 catcaccaag gacacctcca aaaaccaggt ggtcctacaa tgaccaacat ggaccctgtg 60 gacacagcca catattactg tgcacacata cgtccgggta tctggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4319 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4319 His His Gln Gly His Leu Gln Lys Pro Gly Gly Pro Thr Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ile Arg Pro 20 25 30 Gly Ile Trp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4320 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4320 atcaccaagg acacctccaa aaaccaggtg gtccttacaa tgaccaacat ggaccctgtg 60 gacacagcca catattactg tgcacacata cgtccgggta tctggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4321 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4321 Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ile Arg Pro 20 25 30 Gly Ile Trp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4322 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4322 Cys Ala Arg Gly Ser Gly Ser Tyr Ser Phe Phe Asp Tyr Trp 1 5 10 <210> 4323 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4323 ttttcagtag acacgtctaa gaaccagttc tccctgaagc tgagctctgt gactgccgcg 60 gacacggccg tgtattactg tgcgagaggg agtgggagct actccttctt tgactactgg 120 ggccaggga 129 <210> 4324 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4324 Phe Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Ser Gly 20 25 30 Ser Tyr Ser Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4325 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4325 atatcagtag acacgtctaa gaaccagttc tccctgaagc tgagctctgt gactgccgcg 60 gacacggccg tgtattactg tgcgagaggg agtgggagct actccttctt tgactactgg 120 ggccaggga 129 <210> 4326 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4326 Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Ser Gly 20 25 30 Ser Tyr Ser Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4327 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4327 atatcagcag acacgtctaa gaaccagttc tccctgaagc tgaactctgt gactgccgcg 60 gacacggccg tgtattactg tgcgagaggg agtgggagct actccttctt tgactactgg 120 ggccaggga 129 <210> 4328 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4328 Ile Ser Ala Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Asn Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Ser Gly 20 25 30 Ser Tyr Ser Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4329 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4329 Cys Ala Arg Val Lys Tyr Gly Phe Gly Leu Tyr Gly Met Asp Val Trp 1 5 10 15 <210> 4330 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4330 tgggacaacg ccaagaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgcgag agtcaagtac ggttttggcc tctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4331 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4331 Trp Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Lys Tyr Gly Phe 20 25 30 Gly Leu Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4332 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4332 tgggacaacg ccaacaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgcgag agtcaagtac ggttttggcc tctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4333 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4333 Trp Asp Asn Ala Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Lys Tyr Gly Phe 20 25 30 Gly Leu Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4334 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4334 agggacaacg ccaagaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgcgag agtcaagtac ggttttggcc tctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4335 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4335 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Lys Tyr Gly Phe 20 25 30 Gly Leu Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4336 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4336 Cys Ala Arg Gly Glu Pro Arg Ser Gly Ser Tyr Tyr Trp Phe Asp Tyr 1 5 10 15 Trp <210> 4337 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4337 cacaaatcca agaacacgct gtatcttcaa atgaacagcc tgagagcgga ggacacggcc 60 gtgtattact gtgcgagagg tgagcctcgc agtgggagct actactggtt tgactactgg 120 ggccaggga 129 <210> 4338 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4338 His Lys Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Glu Pro Arg Ser Gly 20 25 30 Ser Tyr Tyr Trp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4339 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4339 gacaaatcca agaacacgct gtatcttcaa atgaacagcc tgagagcgga ggacacggcc 60 gtgtattact gtgcgagagg tgagcctcgc agtgggagct actactggtt tgactactgg 120 ggccaggga 129 <210> 4340 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4340 Asp Lys Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Glu Pro Arg Ser Gly 20 25 30 Ser Tyr Tyr Trp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4341 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4341 cacaaatcca acaacacgct gtatcttcaa atgaacagcc tgagagcgga ggacacggcc 60 gtgtattact gtgcgagagg tgagcctcgc agtgggagct actactggtt tgactactgg 120 ggccaggga 129 <210> 4342 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4342 His Lys Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Glu Pro Arg Ser Gly 20 25 30 Ser Tyr Tyr Trp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4343 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4343 Cys Ala Lys Asp Val Asp Ile Val Ala Val Pro Trp 1 5 10 <210> 4344 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4344 ttcgccatct ccagagacaa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgagggca cggccgtata ttactgtgcg aaagacgtgg atatagtggc tgtcccgtgg 120 ggccaggga 129 <210> 4345 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4345 Phe Ala Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Gly Thr Ala Val Tyr Tyr Cys Ala Lys Asp 20 25 30 Val Asp Ile Val Ala Val Pro Trp Gly Gln Gly 35 40 <210> 4346 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4346 ttcaccatct ccagagacaa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagacgtgg atatagtggc tgtcccgtgg 120 ggccaggga 129 <210> 4347 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4347 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp 20 25 30 Val Asp Ile Val Ala Val Pro Trp Gly Gln Gly 35 40 <210> 4348 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4348 ttcaccatct ccagacacaa ttccaacaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagacgtgg atatagtggc tgtcccgtgg 120 ggccaggga 129 <210> 4349 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4349 Phe Thr Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp 20 25 30 Val Asp Ile Val Ala Val Pro Trp Gly Gln Gly 35 40 <210> 4350 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4350 Cys Ala Lys Glu Ser Gly Ser Tyr Ser Phe Asp Tyr Trp 1 5 10 <210> 4351 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4351 accatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gagggcacgg ccgtatatta ctgtgcgaaa gaaagtggga gctactcatt tgactactgg 120 ggccaggga 129 <210> 4352 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4352 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Gly Thr Ala Val Tyr Tyr Cys Ala Lys Glu Ser 20 25 30 Gly Ser Tyr Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4353 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4353 accatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gaaagtggga gctactcatt tgactactgg 120 ggccaggga 129 <210> 4354 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4354 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Ser 20 25 30 Gly Ser Tyr Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4355 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4355 accatctcca gacacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gaaagtggga gctactcatt tgactactgg 120 ggccaggga 129 <210> 4356 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4356 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Ser 20 25 30 Gly Ser Tyr Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4357 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4357 Cys Ala Arg Glu Arg Gly Ser Ser Trp Pro Arg Asp Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 4358 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4358 tgcacagcct acttggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagaga ggggcagcag ctggcctcgg gactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4359 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4359 Cys Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Arg Gly Ser Ser Trp Pro Arg Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4360 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4360 tgcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagaga ggggcagcag ctggcctcgg gactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4361 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4361 Cys Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Arg Gly Ser Ser Trp Pro Arg Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4362 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4362 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagaga ggggcagcag ctggcctcgg gactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4363 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4363 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Arg Gly Ser Ser Trp Pro Arg Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4364 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4364 Cys Ala Arg Gly Asn Phe Met Thr Gly Thr Pro Gly Ala Phe Asp Ile 1 5 10 15 Trp <210> 4365 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4365 gacacgtccg agaaccagtt ctccctgaag ctgacctctg tgaccgccgc ggacacgact 60 gtatattact gtgcgagagg caattttatg actggaaccc caggggcttt tgatatctgg 120 ggccaaggg 129 <210> 4366 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4366 Asp Thr Ser Glu Asn Gln Phe Ser Leu Lys Leu Thr Ser Val Thr Ala 1 5 10 15 Ala Asp Thr Thr Val Tyr Tyr Cys Ala Arg Gly Asn Phe Met Thr Gly 20 25 30 Thr Pro Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4367 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4367 cacacgtccg agaaccagtt ctccctgaag ctgacctctg tgaccgccgc ggacacgact 60 gtatattact gtgcgagagg caattttatg actggaaccc caggggcttt tgatatctgg 120 ggccaaggg 129 <210> 4368 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4368 His Thr Ser Glu Asn Gln Phe Ser Leu Lys Leu Thr Ser Val Thr Ala 1 5 10 15 Ala Asp Thr Thr Val Tyr Tyr Cys Ala Arg Gly Asn Phe Met Thr Gly 20 25 30 Thr Pro Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4369 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4369 cacacgtccg acaaccagtt ctccctgaag ctgacctctg tgaccgccgc ggacacgact 60 gtatattact gtgcgagagg caattttatg actggaaccc caggggcttt tgatatctgg 120 ggccaaggg 129 <210> 4370 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4370 His Thr Ser Asp Asn Gln Phe Ser Leu Lys Leu Thr Ser Val Thr Ala 1 5 10 15 Ala Asp Thr Thr Val Tyr Tyr Cys Ala Arg Gly Asn Phe Met Thr Gly 20 25 30 Thr Pro Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4371 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4371 Cys Thr Arg Gly Gly Val Gly Gly Val Ser Ala Pro Tyr Asp Trp 1 5 10 15 <210> 4372 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4372 gccagagaca attccaagaa cacgctgtat cttcaaatga accgcctgag agccgaggac 60 acgggcgtgt atttatgtac gagagggggt gtaggggggg ttagtgcccc ttacgactgg 120 ggcctggga 129 <210> 4373 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4373 Ala Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Arg Leu 1 5 10 15 Arg Ala Glu Asp Thr Gly Val Tyr Leu Cys Thr Arg Gly Gly Val Gly 20 25 30 Gly Val Ser Ala Pro Tyr Asp Trp Gly Leu Gly 35 40 <210> 4374 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4374 gccagagaca attccaagaa cacgctgtat cttcaaatga acagcctgag agccgaggac 60 acgggcgtgt atttatgtac gagagggggt gtaggggggg ttagtgcccc ttacgactgg 120 ggcctggga 129 <210> 4375 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4375 Ala Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Gly Val Tyr Leu Cys Thr Arg Gly Gly Val Gly 20 25 30 Gly Val Ser Ala Pro Tyr Asp Trp Gly Leu Gly 35 40 <210> 4376 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4376 gccagagaca attccaagaa cacgctgtat cttcaaatga acagcctgag agccgaggac 60 acgggcgtgt atttatgtac gagagggggg gtaggggggg ttagtgcccc ttacgactgg 120 ggcctggga 129 <210> 4377 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4377 Cys Ala Lys Asn His Leu Gly Met Tyr Tyr Phe Asp Tyr Trp 1 5 10 <210> 4378 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4378 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaaac catcttggga tgtactactt tgactactgg 120 ggccaggga 129 <210> 4379 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4379 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asn His Leu 20 25 30 Gly Met Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4380 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4380 atctccatag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaaac catcttggga tgtactactt tgactactgg 120 ggccaggga 129 <210> 4381 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4381 Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asn His Leu 20 25 30 Gly Met Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4382 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4382 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaaac catcttggga tgtactactt tgactactgg 120 ggccaggga 129 <210> 4383 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4383 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asn His Leu 20 25 30 Gly Met Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4384 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4384 Cys Ala Lys Asp Gln Arg Gly Leu Val Asn Gly Met Asp Val Trp 1 5 10 15 <210> 4385 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4385 ctccagagac aacgccagaa ttccgtgtat ttgcaaatga acagtctgag aattgaggac 60 acggccctat attattgtgc taaggatcag cggggtctgg tgaatggtat ggacgtctgg 120 ggccaaggg 129 <210> 4386 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4386 Leu Gln Arg Gln Arg Gln Asn Ser Val Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ile Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Gln Arg Gly 20 25 30 Leu Val Asn Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4387 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4387 tccagagaca acgccaagaa ttccgtgtat ttgcaaatga acagtctgat aattgaggac 60 acggccctat attattgtgc taaggatcag cggggtctgg tgaatggtat ggacgtctgg 120 ggccaaggg 129 <210> 4388 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4388 Ser Arg Asp Asn Ala Lys Asn Ser Val Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Ile Ile Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Gln Arg Gly 20 25 30 Leu Val Asn Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4389 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4389 tccagagaca acgccaagaa ttccgtgtat ttgcaaatga acagtctgag aattgaggac 60 acggccctat attattgtgc taaggatcag cggggtctgg tgaatggtat ggacgtctgg 120 ggccaaggg 129 <210> 4390 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4390 Ser Arg Asp Asn Ala Lys Asn Ser Val Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ile Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Gln Arg Gly 20 25 30 Leu Val Asn Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4391 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4391 Cys Val Arg Gly Ala Ser Gln Tyr Tyr Gly Ser Glu Lys Tyr Leu Tyr 1 5 10 15 Tyr Phe Asp Tyr Trp 20 <210> 4392 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4392 tgcacagcct acttggaggt gagcagcctg agatcagacg acacggccgt gtattactgt 60 gtgagaggcg ccagtcaata ctatggctca gaaaaatatt tgtactactt tgactactgg 120 ggccaggga 129 <210> 4393 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4393 Cys Thr Ala Tyr Leu Glu Val Ser Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Val Arg Gly Ala Ser Gln Tyr Tyr Gly Ser Glu Lys 20 25 30 Tyr Leu Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4394 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4394 tgcacagcct acatggaggt gagcagcctg agatcagacg acacggccgt gtattactgt 60 gtgagaggcg ccagtcaata ctatggctca gaaaaatatt tgtactactt tgactactgg 120 ggccaggga 129 <210> 4395 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4395 Cys Thr Ala Tyr Met Glu Val Ser Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Val Arg Gly Ala Ser Gln Tyr Tyr Gly Ser Glu Lys 20 25 30 Tyr Leu Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4396 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4396 agcacagcct acatggaggt gagcagcctg agatcagacg acacggccgt gtattactgt 60 gtgagaggcg ccagtcaata ctatggctca gaaaaatatt tgtactactt tgactactgg 120 ggccaggga 129 <210> 4397 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4397 Ser Thr Ala Tyr Met Glu Val Ser Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Val Arg Gly Ala Ser Gln Tyr Tyr Gly Ser Glu Lys 20 25 30 Tyr Leu Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4398 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4398 Cys Ala Arg Asp Leu Gly Tyr Ser Ser Ser Trp Gly Gly Ala Gly Asn 1 5 10 15 Trp Phe Asp Pro Trp 20 <210> 4399 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4399 tgcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatc ttgggtatag cagcagctgg ggaggggcgg gaaactggtt cgacccctgg 120 ggccaggga 129 <210> 4400 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4400 Cys Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Leu Gly Tyr Ser Ser Ser Trp Gly Gly 20 25 30 Ala Gly Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4401 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4401 agcacagtct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatc ttgggtatag cagcagctgg ggaggggcgg gaaactggtt cgacccctgg 120 ggccaggga 129 <210> 4402 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4402 Ser Thr Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Leu Gly Tyr Ser Ser Ser Trp Gly Gly 20 25 30 Ala Gly Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4403 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4403 agcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatc ttgggtatag cagcagctgg ggaggggcgg gaaactggtt cgacccctgg 120 ggccaggga 129 <210> 4404 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4404 Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Leu Gly Tyr Ser Ser Ser Trp Gly Gly 20 25 30 Ala Gly Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4405 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4405 Cys Ala Arg Gly Tyr Ala Leu Asp Gly Met Asp Val Trp 1 5 10 <210> 4406 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4406 accatgacca ggaacacctc cataagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ggttacgcct tggacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4407 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4407 Thr Met Thr Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Tyr 20 25 30 Ala Leu Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4408 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4408 accatgacca gcaacacctc cataagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ggttacgcct tggacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4409 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4409 Thr Met Thr Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Tyr 20 25 30 Ala Leu Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4410 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4410 accatgacca gcaacacctc cataaccaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ggttacgcct tggacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4411 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4411 Thr Met Thr Ser Asn Thr Ser Ile Thr Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Tyr 20 25 30 Ala Leu Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4412 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4412 Cys Ala Arg Glu Asp Gly Asn Val Leu Asp Tyr Trp 1 5 10 <210> 4413 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4413 ttaaccgtca gtccggacac atccaagaac ctgttctccc tgcagttgca gtctgtggtt 60 cccgacgata cggctgtgta ttactgtgcc agagaagacg gcaatgtcct tgactactgg 120 ggccaggga 129 <210> 4414 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4414 Leu Thr Val Ser Pro Asp Thr Ser Lys Asn Leu Phe Ser Leu Gln Leu 1 5 10 15 Gln Ser Val Val Pro Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu 20 25 30 Asp Gly Asn Val Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4415 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4415 ataaccgtcc gtccgcacac atccaagaac cagttctccc tgcagttgca gtctgtggtt 60 cccgacgata cggctgtgta ttactgtgcc agagaagacg gcaatgtcct tgactactgg 120 ggccaggga 129 <210> 4416 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4416 Ile Thr Val Arg Pro His Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu 1 5 10 15 Gln Ser Val Val Pro Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu 20 25 30 Asp Gly Asn Val Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4417 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4417 ataaccgtca gtccggacac atccaagaac cagttctccc tgcagttgca gtctgtggtt 60 cccgacgata cggctgtgta ttactgtgcc agagaagacg gcaatgtcct tgactactgg 120 ggccaggga 129 <210> 4418 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4418 Ile Thr Val Ser Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu 1 5 10 15 Gln Ser Val Val Pro Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu 20 25 30 Asp Gly Asn Val Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4419 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4419 Cys Ala Lys Thr His Tyr Tyr Asp Ser Ser Gly Ser Trp Val His Phe 1 5 10 15 Asp Tyr Trp <210> 4420 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4420 tccaataata cgctgtatct gcaaatgaac ggcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aaacccatta ctatgatagt agtggttcct gggtccactt tgactactgg 120 ggccaggga 129 <210> 4421 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4421 Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Gly Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Thr His Tyr Tyr Asp Ser Ser Gly 20 25 30 Ser Trp Val His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4422 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4422 tccaagaata cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aaacccatta ctatgatagt agtggttcct gggtccactt tgactactgg 120 ggccaggga 129 <210> 4423 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4423 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Thr His Tyr Tyr Asp Ser Ser Gly 20 25 30 Ser Trp Val His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4424 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4424 tccaagaata cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtacat 60 tactgtgcga aaacccatta ctatgatagt agtggttcct gggtccactt tgactactgg 120 ggccaggga 129 <210> 4425 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4425 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val His Tyr Cys Ala Lys Thr His Tyr Tyr Asp Ser Ser Gly 20 25 30 Ser Trp Val His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4426 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4426 Cys Ala Arg Ala Ile Ser Thr Arg Gly Tyr Phe Asp Tyr Trp 1 5 10 <210> 4427 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4427 catctccaga gaaatgccaa gaactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagagcc atctccaccc gggggtactt tgactactgg 120 ggccaggga 129 <210> 4428 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4428 His Leu Gln Arg Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Ile Ser 20 25 30 Thr Arg Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4429 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4429 atctccatag aaaatgccaa gaactccttg tatcttcaaa tgaacagcct gagagccggt 60 gacacggctg tgtattactg tgcaagagcc atctccaccc gggggtactt tgactactgg 120 ggccaggga 129 <210> 4430 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4430 Ile Ser Ile Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Ile Ser 20 25 30 Thr Arg Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4431 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4431 atctccagag aaaatgccaa gaactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagagcc atctccaccc gggggtactt tgactactgg 120 ggccaggga 129 <210> 4432 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4432 Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Ile Ser 20 25 30 Thr Arg Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4433 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4433 Cys Thr Arg Gln Ser Asp Tyr Tyr Asp Ser Ser Gly Thr Lys Thr Thr 1 5 10 15 Phe Asp Tyr Trp 20 <210> 4434 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4434 aagaacacgg cgtatctgca aatgaacagc ctgaaaaccg aggacacggc cgtgtattac 60 tgtactagac aatccgatta ctatgatagt agtggtacca aaacgacttt tgactactgg 120 ggccaggga 129 <210> 4435 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4435 Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Thr Arg Gln Ser Asp Tyr Tyr Asp Ser Ser Gly 20 25 30 Thr Lys Thr Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4436 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4436 aacaacacgg cgtatctgca aatgaacagc cttaaaaccg aggacacggc cgtgtattac 60 tgtactagac aatccgatta ctatgatagt agtggtacca aaacgacttt tgactactgg 120 ggccaggga 129 <210> 4437 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4437 Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Thr Arg Gln Ser Asp Tyr Tyr Asp Ser Ser Gly 20 25 30 Thr Lys Thr Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4438 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4438 aacaacacgg cgtatctgca aatgaacagc ctgaaacccg aggacacggc cgtgtattac 60 tgtactagac aatccgatta ctatgatagt agtggtacca aaacgacttt tgactactgg 120 ggccaggga 129 <210> 4439 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4439 Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Pro Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Thr Arg Gln Ser Asp Tyr Tyr Asp Ser Ser Gly 20 25 30 Thr Lys Thr Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4440 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4440 Cys Ala Ser Pro Asp Pro Leu Gly Ser Val Ala Asp Leu Asp Tyr Trp 1 5 10 15 <210> 4441 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4441 tgggacacat ccgcgagcac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 gctgtgtatt actgtgcgag tccggacccc ttgggttcag tggctgacct tgactactgg 120 ggccaggga 129 <210> 4442 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4442 Trp Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Pro Asp Pro Leu Gly 20 25 30 Ser Val Ala Asp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4443 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4443 agtgacaggt ccgtgagcac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 gctgtgtatt actgtgcgag tccggacccc ttgggttcag tggctgacct tgactactgg 120 ggccaggga 129 <210> 4444 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4444 Ser Asp Arg Ser Val Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Pro Asp Pro Leu Gly 20 25 30 Ser Val Ala Asp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4445 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4445 agggacacat ccgcgagcac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 gctgtgtatt actgtgcgag tccggacccc ttgggttcag tggctgacct tgactactgg 120 ggccaggga 129 <210> 4446 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4446 Arg Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Pro Asp Pro Leu Gly 20 25 30 Ser Val Ala Asp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4447 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4447 Cys Ala Arg Pro His Ser Pro Gly Gly Ser Tyr Pro Asn Tyr Phe Asp 1 5 10 15 Tyr Trp <210> 4448 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4448 acgtccatca gtaccgccta cctgcagtgg ggcagcctga aggcctcgga caccgccatc 60 tattactgtg cgagacccca ttcccccggt gggagctacc caaattactt tgactactgg 120 ggccaggga 129 <210> 4449 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4449 Thr Ser Ile Ser Thr Ala Tyr Leu Gln Trp Gly Ser Leu Lys Ala Ser 1 5 10 15 Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Pro His Ser Pro Gly Gly Ser 20 25 30 Tyr Pro Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4450 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4450 acgtccatca gcaccgccta cctgcagtgg ggcagcctga aggcctcgga caccgccatc 60 tattactgtg cgagacccca ttcccccggt gggagctacc caaattactt tgactactgg 120 ggccaggga 129 <210> 4451 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4451 aagtccatca gcaccgccta cctgcagtgg ggcagcctga aggcctcgga caccgccatc 60 tattactgtg cgagacccca ttcccccggt gggagctacc cgaattactt tgactactgg 120 ggccaggga 129 <210> 4452 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4452 Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Gly Ser Leu Lys Ala Ser 1 5 10 15 Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Pro His Ser Pro Gly Gly Ser 20 25 30 Tyr Pro Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4453 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4453 Cys Ala Arg Ala Gly Arg Met Arg Gly Val Arg Pro Gly Gly Met Asp 1 5 10 15 Val Trp <210> 4454 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4454 tatgccaaga actccttgta tcttcaaatg aacagcctga gagccgggga cacggctgtg 60 tattactgtg caagagcagg gcgtatgcgg ggagttcggc cggggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4455 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4455 Tyr Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Gly 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Gly Arg Met Arg Gly Val 20 25 30 Arg Pro Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4456 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4456 aatgccaaga actccttgta tcttcaaatg aacagcctga gagccgggga cacggctgtg 60 tattactgtg caagagcagg tcgtatgcgg ggagttcggc cggggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4457 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4457 Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Gly 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Gly Arg Met Arg Gly Val 20 25 30 Arg Pro Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4458 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4458 aatgccaaga actccttgta tcttcaaatg aacagcctga gagccgggga cacggctgtg 60 tattactgtg caagagcagg gcgtatgcgg ggagtgcggc cggggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4459 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4459 Cys Ala Arg Val Gly Ser Gly Trp Tyr Glu Asp Tyr Trp 1 5 10 <210> 4460 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4460 accatctcca tacacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gtcggcagtg gctggtacga ggactactgg 120 ggccaggga 129 <210> 4461 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4461 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly 20 25 30 Ser Gly Trp Tyr Glu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4462 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4462 accatctcca gagacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gtcggcagtg gctggtacga ggactactgg 120 ggccaggga 129 <210> 4463 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4463 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly 20 25 30 Ser Gly Trp Tyr Glu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4464 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4464 accatctcca gacacaattc caacaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gtcggcagtg gctggtacga ggactactgg 120 ggccaggga 129 <210> 4465 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4465 Thr Ile Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly 20 25 30 Ser Gly Trp Tyr Glu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4466 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4466 Cys Ala Arg Asp Pro Trp Thr Gly Thr Thr Pro Thr Arg Ala Ile Asp 1 5 10 15 Ile Trp <210> 4467 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4467 acatccacgt gcacaggcta cttggagctg aggagcctga gatttgacga cacggccgtg 60 tattattgtg cgagagaccc gtggactgga acgacgccaa cgcgtgctat tgatatctgg 120 ggccaaggg 129 <210> 4468 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4468 Thr Ser Thr Cys Thr Gly Tyr Leu Glu Leu Arg Ser Leu Arg Phe Asp 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro Trp Thr Gly Thr Thr 20 25 30 Pro Thr Arg Ala Ile Asp Ile Trp Gly Gln Gly 35 40 <210> 4469 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4469 acatccacga gcacaggcta cttggagctg aggagcctga gatttgacga cacggccgtg 60 tattattgtg cgagagaccc gtggactgga acgacgccaa cgcgtgctat tgatatctgg 120 ggccaaggg 129 <210> 4470 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4470 Thr Ser Thr Ser Thr Gly Tyr Leu Glu Leu Arg Ser Leu Arg Phe Asp 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro Trp Thr Gly Thr Thr 20 25 30 Pro Thr Arg Ala Ile Asp Ile Trp Gly Gln Gly 35 40 <210> 4471 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4471 acatccacga gcacaggcta catggagctg aggagcctga gatttgacga cacggccgtg 60 tattattgtg cgagagaccc gtggactgga acgacgccaa cgcgtgctat tgatatctgg 120 ggccaaggg 129 <210> 4472 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4472 Thr Ser Thr Ser Thr Gly Tyr Met Glu Leu Arg Ser Leu Arg Phe Asp 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro Trp Thr Gly Thr Thr 20 25 30 Pro Thr Arg Ala Ile Asp Ile Trp Gly Gln Gly 35 40 <210> 4473 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4473 Cys Ala Arg Ala Asp Gly Thr Gly Tyr Tyr Leu Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 4474 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4474 gtagacaggc ccaagaacca gttctccctg aagctgagct ctgtgaccgc cgcggacacg 60 gccgtgtatt actgtgccag agctgacggg actggttatt acctctactt tgactactgg 120 ggccaggga 129 <210> 4475 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4475 Val Asp Arg Pro Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Asp Gly Thr Gly 20 25 30 Tyr Tyr Leu Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4476 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4476 gtagacaggt ccaagaacca gttctccctg aagctgagct ctgtgaccgc cgcggacacg 60 gccgtgtatt actgtgccag agctgacggg actggttatt acctctactt tgactactgg 120 ggccaggga 129 <210> 4477 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4477 Val Asp Arg Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Asp Gly Thr Gly 20 25 30 Tyr Tyr Leu Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4478 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4478 gtagacaggc ccaacaacca gttctccctg aagctgagct ctgtgaccgc cgcggacacg 60 gccgtgtatt actgtgccag agctgacggg actggttatt acctctactt tgactactgg 120 ggccaggga 129 <210> 4479 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4479 Val Asp Arg Pro Asn Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Asp Gly Thr Gly 20 25 30 Tyr Tyr Leu Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4480 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4480 Cys Thr Thr Glu Gly Ser Tyr Phe Leu Phe Asp Pro Trp 1 5 10 <210> 4481 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4481 accatctcaa gagatgattc aaaaaacacg ctgtatctgc aaatgaacag cctgaaaacc 60 gaggacacag ccgtgtatta ctgtaccaca gaggggtcgt attttttgtt cgacccctgg 120 ggccaggga 129 <210> 4482 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4482 Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Glu Gly 20 25 30 Ser Tyr Phe Leu Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4483 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4483 aacatctcaa gagatgattc aaaaaacacg ctgtatctgc aaatgaacag cctgaaaacc 60 gatgacacag ccgtgtatta ctgtaccaca gaggggtcgt attttttgtt cgacccctgg 120 ggccaggga 129 <210> 4484 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4484 Asn Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Asp Asp Thr Ala Val Tyr Tyr Cys Thr Thr Glu Gly 20 25 30 Ser Tyr Phe Leu Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4485 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4485 ccatctcaag agatgattca aaaaaacacg ctgtatctgc aaatgaacag cctgaaaacc 60 gaggacacag ccgtgtatta ctgtaccaca gaggggtcgt attttttgtt cgacccctgg 120 ggccaggga 129 <210> 4486 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4486 Pro Ser Gln Glu Met Ile Gln Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Glu Gly 20 25 30 Ser Tyr Phe Leu Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4487 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4487 Cys Ser His Arg Arg Val Gly Leu Ala Thr Gly Phe Asp Ile Trp 1 5 10 15 <210> 4488 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4488 actaaggact cctccaaaaa cctggtggtc ctcacaatga ccaacatgga ccctgcggac 60 acggccacat attactgttc acacagaaga gttgggctgg cgactggttt tgatatctgg 120 ggccaaggg 129 <210> 4489 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4489 Thr Lys Asp Ser Ser Lys Asn Leu Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Ala Asp Thr Ala Thr Tyr Tyr Cys Ser His Arg Arg Val Gly 20 25 30 Leu Ala Thr Gly Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4490 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4490 actaaggaca cctccaaaaa ccaggtggtc ctcacaatga ccaacatgga ccctgcggac 60 acggccacat attactgttc acacagaaga gttgggctgg cgactggttt tgatatctgg 120 ggccaaggg 129 <210> 4491 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4491 Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Ala Asp Thr Ala Thr Tyr Tyr Cys Ser His Arg Arg Val Gly 20 25 30 Leu Ala Thr Gly Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4492 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4492 actaaggaca actccaaaaa cctggtggtc ctcacaatga ccaacatgga ccctgcggac 60 acggccacat attactgttc acacagaaga gttgggctgg cgactggttt tgatatctgg 120 ggccaaggg 129 <210> 4493 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4493 Thr Lys Asp Asn Ser Lys Asn Leu Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Ala Asp Thr Ala Thr Tyr Tyr Cys Ser His Arg Arg Val Gly 20 25 30 Leu Ala Thr Gly Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4494 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4494 Cys Ala Gly Thr Met Val Gln Gly Val Pro Pro Ala Arg Gln Asn Trp 1 5 10 15 Phe Asp Pro Trp 20 <210> 4495 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4495 tcgagcacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgggga ctatggttca gggagtcccc cccgcgcgcc aaaactggtt cgacccctgg 120 ggtcaggga 129 <210> 4496 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4496 Ser Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Gly Thr Met Val Gln Gly Val Pro Pro Ala 20 25 30 Arg Gln Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4497 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4497 acgagcacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgggga ctatggttca gggagtcccc cccgcgcgcc aaaactggtt cgacccctgg 120 ggtcaggga 129 <210> 4498 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4498 Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Gly Thr Met Val Gln Gly Val Pro Pro Ala 20 25 30 Arg Gln Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4499 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4499 acgagcacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgggga ctatggttca gggagtcccc cccgcgcgcc aaaactggtt cgacccctgg 120 ggccaggga 129 <210> 4500 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4500 Cys Ala Lys Gly Arg Arg Gly Ser Tyr Phe Asp Tyr Trp 1 5 10 <210> 4501 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4501 accatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ggacgccgtg ggagctactt tgactactgg 120 ggccaggga 129 <210> 4502 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4502 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg 20 25 30 Arg Gly Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4503 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4503 accatctcca tacataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ggacgccgtg ggagctactt tgactactgg 120 ggccaggga 129 <210> 4504 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4504 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg 20 25 30 Arg Gly Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4505 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4505 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ggacgccgtg ggagctactt tgactactgg 120 ggccaggga 129 <210> 4506 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4506 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg 20 25 30 Arg Gly Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4507 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4507 Cys Ala Lys Phe Trp Phe Gly Glu Leu Leu Pro Asp Tyr Trp 1 5 10 <210> 4508 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4508 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaattc tggttcgggg agttattacc ggactactgg 120 ggccaggga 129 <210> 4509 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4509 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Phe Trp Phe 20 25 30 Gly Glu Leu Leu Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4510 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4510 atctccagat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaattc tggttcgggg agttattacc ggactactgg 120 ggccaggga 129 <210> 4511 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4511 Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Phe Trp Phe 20 25 30 Gly Glu Leu Leu Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4512 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4512 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaattc tggttcgggg agttattacc ggactactgg 120 ggccaggga 129 <210> 4513 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4513 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Phe Trp Phe 20 25 30 Gly Glu Leu Leu Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 4514 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4514 Cys Ala Arg Asp Pro Gly Thr Asn Thr Trp Tyr Gly Leu Asp Val Trp 1 5 10 15 <210> 4515 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4515 tgggacacct ccacaagcac tgcctacatg gagctgagca gcctgagatc tgacgacgcg 60 gccgtgtatt actgtgcgag ggatccgggc accaacacct ggtacggtct ggacgtctgg 120 ggccaaggg 129 <210> 4516 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4516 Trp Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Asp Asp Ala Ala Val Tyr Tyr Cys Ala Arg Asp Pro Gly Thr Asn 20 25 30 Thr Trp Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 4517 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4517 agggacacct ccataagcac agcctacatg gaactgagca gcctgagatc tgacgacgcg 60 gccgtctatt actgtgcgag ggatccgggc accaacacct ggtacggtct ggacgtctgg 120 ggcgaaggg 129 <210> 4518 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4518 Arg Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Asp Asp Ala Ala Val Tyr Tyr Cys Ala Arg Asp Pro Gly Thr Asn 20 25 30 Thr Trp Tyr Gly Leu Asp Val Trp Gly Glu Gly 35 40 <210> 4519 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4519 agggacacct ccacaagcac agcctacatg gagctgagca gcctgagatc tgacgacgcg 60 gccgtgtatt actgtgcgag ggatccgggc accaacacct ggtacggtct ggacgtctgg 120 ggccaaggg 129 <210> 4520 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4520 Arg Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Asp Asp Ala Ala Val Tyr Tyr Cys Ala Arg Asp Pro Gly Thr Asn 20 25 30 Thr Trp Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 4521 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4521 Cys Ala Lys Met Ser Arg Ala Leu Gln Ile Phe Asp Tyr Trp 1 5 10 <210> 4522 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4522 atctccatag ataattccaa gaatacgctg tatctgcaaa tgaatagcct gagagccgag 60 gacacggccg tatattattg tgcgaaaatg tcgagagcac tccaaatttt tgactactgg 120 ggccaggga 129 <210> 4523 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4523 Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Met Ser Arg 20 25 30 Ala Leu Gln Ile Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4524 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4524 atctccagat ataattccaa gaatacgctg tatctgcaaa tgaatagcct gagagccgag 60 gacacggccg tatattattg tgcgaaaatg tcgagagcac tccaaatttt tgactactgg 120 ggccaggga 129 <210> 4525 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4525 Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Met Ser Arg 20 25 30 Ala Leu Gln Ile Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4526 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4526 atctccagag ataattccaa gaatacgctg tatctgcaaa tgaatagcct gagagccgag 60 gacacggccg tatattattg tgcgaaaatg tcgagagcac tccaaatttt tgactactgg 120 ggccaggga 129 <210> 4527 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4527 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Met Ser Arg 20 25 30 Ala Leu Gln Ile Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4528 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4528 Cys Ala Arg Trp Asp Tyr Tyr Gly Ser Gly Ser Tyr Phe Leu Pro Trp 1 5 10 15 Pro Gly Asp Trp Tyr Phe Asp Leu Trp 20 25 <210> 4529 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4529 ctgcaaatga acagcctgag agccgaggac acggccgtat attactgtgc gagatgggat 60 tactatggtt cggggagtta tttcctcccc tggccagggg actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4530 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4530 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Trp Asp Tyr Tyr Gly Ser Gly Ser Tyr Phe Leu Pro Trp Pro 20 25 30 Gly Asp Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4531 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4531 ctgaaaatga actgcctgag agccgaggac acggccgtat attactgtgc gagatgggat 60 tactatggtt cggggagtta tttcctcccc tggccagggg actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4532 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4532 Leu Lys Met Asn Cys Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Trp Asp Tyr Tyr Gly Ser Gly Ser Tyr Phe Leu Pro Trp Pro 20 25 30 Gly Asp Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4533 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4533 ctgaaaatga accgcctgag agccgaggac acggccgtat attactgtgc gagatgggat 60 tactatggtt cggggagtta tttcctcccc tggccagggg actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4534 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4534 Leu Lys Met Asn Arg Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Trp Asp Tyr Tyr Gly Ser Gly Ser Tyr Phe Leu Pro Trp Pro 20 25 30 Gly Asp Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4535 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4535 Cys Ala Arg Arg Ser Val Gly Gly Arg Tyr Phe Asp Tyr Trp 1 5 10 <210> 4536 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4536 atctccatat acaattccaa gaacactctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgcggagg tcagtgggtg gtcgttattt tgactactgg 120 ggccaggga 129 <210> 4537 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4537 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Arg Ser Val 20 25 30 Gly Gly Arg Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4538 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4538 atctccatac acaattccaa gaacactctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgcggagg tcagtgggtg gtcgttattt tgactactgg 120 ggccaggga 129 <210> 4539 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4539 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Arg Ser Val 20 25 30 Gly Gly Arg Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4540 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4540 atctccagag acaattccaa gaacactctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgcggagg tcagtgggtg gtcgttattt tgactactgg 120 ggccaggga 129 <210> 4541 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4541 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Arg Ser Val 20 25 30 Gly Gly Arg Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4542 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4542 Cys Ala Arg Ala Arg Gly Ile Thr Met Ile Val Gly Gly Arg Glu Asp 1 5 10 15 Ala Phe Asp Ile Trp 20 <210> 4543 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4543 agcactgcct acatggagct gtggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagcga ggggtattac tatgatagta gggggcagag aggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4544 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4544 Ser Thr Ala Tyr Met Glu Leu Trp Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Ala Arg Gly Ile Thr Met Ile Val Gly Gly 20 25 30 Arg Glu Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4545 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4545 agcactgcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagcga ggggtattac tatgatagta gggggcagag aggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4546 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4546 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Ala Arg Gly Ile Thr Met Ile Val Gly Gly 20 25 30 Arg Glu Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4547 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4547 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagcga ggggtattac tatgatagta gggggcagag aggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4548 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4548 Cys Ala Arg Gly Lys Val Trp Glu Gly Gly Tyr Gly Trp Gly Tyr Trp 1 5 10 15 <210> 4549 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4549 tgggacaacg ccaagaactc actgtttctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgcgag agggaaggtt tgggagggtg gctacggctg gggttactgg 120 ggccaggga 129 <210> 4550 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4550 Trp Asp Asn Ala Lys Asn Ser Leu Phe Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Lys Val Trp Glu 20 25 30 Gly Gly Tyr Gly Trp Gly Tyr Trp Gly Gln Gly 35 40 <210> 4551 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4551 agggacaacg ccaagaactc actgtttctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgcgag agggaaggtt tgggagggtg gctacggctg gggttactgg 120 ggccaggga 129 <210> 4552 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4552 Arg Asp Asn Ala Lys Asn Ser Leu Phe Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Lys Val Trp Glu 20 25 30 Gly Gly Tyr Gly Trp Gly Tyr Trp Gly Gln Gly 35 40 <210> 4553 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4553 agggacaacg ccaagaactc actgtttctg caaatgaaca gcctgagagc cgaggacacg 60 gcagtgtatt actgtgcgag agggaaggtt tgggagggtg gctacggctg gggttactgg 120 ggccaggga 129 <210> 4554 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4554 Cys Ala Arg Gly Leu Phe Tyr Tyr Gly Ser Val Val Ala Lys Ile Pro 1 5 10 15 Gly Gly Tyr Trp 20 <210> 4555 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4555 ataagcacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagag gcctcttcta ctatggttca gtcgtcgcca aaattccggg ggggtactgg 120 ggccaggga 129 <210> 4556 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4556 Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Leu Phe Tyr Tyr Gly Ser Val Val 20 25 30 Ala Lys Ile Pro Gly Gly Tyr Trp Gly Gln Gly 35 40 <210> 4557 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4557 ataagcacac cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagag gcctcttcta ctatggttca gtcgtcgcca aaattccggg ggggtactgg 120 ggccaggga 129 <210> 4558 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4558 Ile Ser Thr Pro Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Leu Phe Tyr Tyr Gly Ser Val Val 20 25 30 Ala Lys Ile Pro Gly Gly Tyr Trp Gly Gln Gly 35 40 <210> 4559 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4559 ataaccacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagag gcctcttcta ctatggttca gtcgtcgcca aaattccggg ggggtactgg 120 ggccaggga 129 <210> 4560 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4560 Ile Thr Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Leu Phe Tyr Tyr Gly Ser Val Val 20 25 30 Ala Lys Ile Pro Gly Gly Tyr Trp Gly Gln Gly 35 40 <210> 4561 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4561 Cys Ala Arg Asp Lys Phe Ser Ser Gly Ser Tyr Tyr Tyr Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 4562 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4562 tcgatgtatc ttcaaatgaa cagcctgaga gccgaggaca cggccgtgta ttactgtgcg 60 agagataaat tttccagtgg gagctactat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4563 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4563 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Lys Phe Ser Ser Gly Ser Tyr Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4564 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4564 acgctgtatc ttcaaatgaa cagcctgaga gccgaggaca cggccgtgta ttactgtgcg 60 agagataaat tttccagtgg gagctactat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4565 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4565 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Lys Phe Ser Ser Gly Ser Tyr Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4566 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4566 acgatgtatc ttcaaatgaa cagcctgaga gccgagtaca cggccgtgta ttactgtgcg 60 agagataaat tttccagtgg gagctactat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4567 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4567 Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Tyr Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Lys Phe Ser Ser Gly Ser Tyr Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4568 <211> 26 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4568 Cys Ala Lys Asp Arg Ala Tyr Tyr Asp Ile Leu Thr Gly Tyr Tyr Gly 1 5 10 15 Thr Tyr Asp Gln Asp Ala Phe Asp Ile Trp 20 25 <210> 4569 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4569 caattgaact gcctgagagc cgaggacacg gccgtatatt actgtgcgaa agatcgggcg 60 tattacgata ttttgactgg ttattatggg acttatgatc aagatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4570 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4570 Gln Leu Asn Cys Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala 1 5 10 15 Lys Asp Arg Ala Tyr Tyr Asp Ile Leu Thr Gly Tyr Tyr Gly Thr Tyr 20 25 30 Asp Gln Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4571 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4571 caaatgaact gcctgagagc cgaggacacg gccgtatatt actgtgcgaa agatcgggcg 60 tattacgata ttttgactgg ttattatggg acttatgatc aagatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4572 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4572 Gln Met Asn Cys Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala 1 5 10 15 Lys Asp Arg Ala Tyr Tyr Asp Ile Leu Thr Gly Tyr Tyr Gly Thr Tyr 20 25 30 Asp Gln Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4573 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4573 caaatgaaca gcctgagagc cgaggacacg gccgtatatt actgtgcgaa agatcgggcg 60 tattacgata ttttgactgg ttattatggg acttatgatc aagatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4574 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4574 Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala 1 5 10 15 Lys Asp Arg Ala Tyr Tyr Asp Ile Leu Thr Gly Tyr Tyr Gly Thr Tyr 20 25 30 Asp Gln Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4575 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4575 Cys Ala Arg Gly Met Ser Leu Leu Asp Tyr Trp 1 5 10 <210> 4576 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4576 cgattcacca tctccaggga caacgccaag aactcactgc ttctgcacat gaacagcctg 60 agagccgagg acgcggccgt gtattactgt gcgagaggga tgagccttct tgactactgg 120 ggccaggga 129 <210> 4577 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4577 Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Leu Leu His 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Ala Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Gly Met Ser Leu Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4578 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4578 cgattcacca cctccaggga caacgccaag aactcactgc ttctgcacat gaacagcctg 60 agagccgagg acgcggccgt gtattactgt gcgagaggga tgagccttct tgactactgg 120 ggccaggga 129 <210> 4579 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4579 Arg Phe Thr Thr Ser Arg Asp Asn Ala Lys Asn Ser Leu Leu Leu His 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Ala Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Gly Met Ser Leu Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4580 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4580 cgattcacca cctccaggga caacgccaag aactcactgc ttctgcacat gaacagcctg 60 agagccgagg acgcggccgt gtattactgt gcgagaggga tgagcctcct tgactactgg 120 ggccaggga 129 <210> 4581 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4581 Cys Ala Arg Gly Gly Arg Gly Arg Pro Gly Tyr Ser Arg Trp Gly Asp 1 5 10 15 Tyr Trp <210> 4582 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4582 tacgccaaga actccctgta tctgcaaatg aacagtctga gagctgagga cacggccttg 60 tattactgtg caagaggagg gcgtgggcgc cccgggtata gcagatgggg ggactactgg 120 ggccaggga 129 <210> 4583 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4583 Tyr Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Arg Gly Gly Arg Gly Arg Pro Gly 20 25 30 Tyr Ser Arg Trp Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 4584 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4584 aacgccaaga actccctgta tctgcaaatg aacagtctga gagctgagga cacggccttg 60 tattactgtg caagaggagg tcgtgggcgc cccgggtata gcagatgggg ggactactgg 120 ggccaggga 129 <210> 4585 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4585 Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Arg Gly Gly Arg Gly Arg Pro Gly 20 25 30 Tyr Ser Arg Trp Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 4586 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4586 caacgccaag aactcctgta tctgcaaatg aacagtctga gagctgagga cacggccttg 60 tattactgtg caagaggagg tcgtgggcgc cccgggtata gcagatgggg ggactactgg 120 ggccaggga 129 <210> 4587 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4587 Gln Arg Gln Glu Leu Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Arg Gly Gly Arg Gly Arg Pro Gly 20 25 30 Tyr Ser Arg Trp Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 4588 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4588 Cys Ala Arg Asp Pro Asn Gly Ser Gly Ser Tyr Tyr Leu Gly Tyr Trp 1 5 10 15 <210> 4589 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4589 tgggacacgt ccacgagcac tgtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agatcccaat ggttcgggga gttactattt aggctactgg 120 ggccaggga 129 <210> 4590 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4590 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro Asn Gly Ser 20 25 30 Gly Ser Tyr Tyr Leu Gly Tyr Trp Gly Gln Gly 35 40 <210> 4591 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4591 tgggacacgc ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agatcccaat ggttcgggga gttactattt aggctactgg 120 ggccaggga 129 <210> 4592 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4592 Trp Asp Thr Pro Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro Asn Gly Ser 20 25 30 Gly Ser Tyr Tyr Leu Gly Tyr Trp Gly Gln Gly 35 40 <210> 4593 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4593 agggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agatcccaat ggttcgggga gttactattt aggctactgg 120 ggccaggga 129 <210> 4594 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4594 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro Asn Gly Ser 20 25 30 Gly Ser Tyr Tyr Leu Gly Tyr Trp Gly Gln Gly 35 40 <210> 4595 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4595 Cys Ala Arg Gly Pro Ser Ile Ala Ala His Pro Leu Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 4596 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4596 tacacgatgt atcttcaaat gaacagcctg agagccgagg acacggccgt gtattactgt 60 gcgagagggc cgagtatagc agctcacccc ctctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4597 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4597 Tyr Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Pro Ser Ile Ala Ala His Pro Leu Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4598 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4598 aacacgctgt atcttcaaat gaacagcctg agagccgagg acacggccgt gtattactgt 60 gcgagagggc cgagtatagc agctcacccc ctctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4599 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4599 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Pro Ser Ile Ala Ala His Pro Leu Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4600 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4600 aacacgctgt atcttcaaat caacagcctg agagccgagg acacggccgt gtattactgt 60 gcgagagggc cgagtatagc agctcacccc ctctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4601 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4601 Asn Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Pro Ser Ile Ala Ala His Pro Leu Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4602 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4602 Cys Thr Thr Pro Tyr Gly Ser Gly Ser Tyr Ser Arg Asp Tyr Trp 1 5 10 15 <210> 4603 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4603 caagagatga ttcaaaaaaa cacgctgtat ctgcaaatga acagcctgaa aaccgaggac 60 acagccgtgt attactgtac cacaccttat ggttcgggga gttattccag agactactgg 120 ggccaggga 129 <210> 4604 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4604 Gln Glu Met Ile Gln Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Pro Tyr Gly Ser 20 25 30 Gly Ser Tyr Ser Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 4605 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4605 tcaagagatg attcaaaaaa cacgctgtat ctgcaaatga acagcctgaa aaccgagggc 60 acagccgtgt attactgtac cacaccttat ggttcgggga gttattccag agactactgg 120 ggccaggga 129 <210> 4606 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4606 Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Gly Thr Ala Val Tyr Tyr Cys Thr Thr Pro Tyr Gly Ser 20 25 30 Gly Ser Tyr Ser Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 4607 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4607 tcaagagatg attcaaaaaa cacgctgtat ctgcaaatga acagcctgaa aaccgaggac 60 acagccgtgt attactgtac cacaccttat ggttcgggga gttattccag agactactgg 120 ggccaggga 129 <210> 4608 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4608 Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Pro Tyr Gly Ser 20 25 30 Gly Ser Tyr Ser Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 4609 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4609 Cys Ala Arg Val Lys Gly Trp Thr Gly Tyr Phe Asp Tyr Trp 1 5 10 <210> 4610 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4610 atctccaggg acaacgccaa gaactcactg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagtt aagggctgga cgggttactt tgactactgg 120 ggccaggga 129 <210> 4611 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4611 Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Lys Gly 20 25 30 Trp Thr Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4612 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4612 atctccaggc acaacgccaa caactcactg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagtt aagggctgga cgggttactt tgactactgg 120 ggccaggga 129 <210> 4613 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4613 Ile Ser Arg His Asn Ala Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Lys Gly 20 25 30 Trp Thr Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4614 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4614 atctccaggc acaaccccaa gaactcactg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagtt aagggctgga cgggttactt tgactactgg 120 ggccaggga 129 <210> 4615 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4615 Ile Ser Arg His Asn Pro Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Lys Gly 20 25 30 Trp Thr Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4616 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4616 Cys Thr Ser Ser Arg Ser Ile Ala Arg Gly Gly Gly Ala Phe Asp Ile 1 5 10 15 Trp <210> 4617 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4617 tattattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagcag tcgaagtata gcaagagggg gtggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 4618 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4618 Tyr Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Ser Arg Ser Ile Ala Arg 20 25 30 Gly Gly Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4619 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4619 gatgattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagcag tcgaagtata gcaagagggg gtggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 4620 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4620 Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Ser Arg Ser Ile Ala Arg 20 25 30 Gly Gly Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4621 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4621 cattattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagcag tcgaagtata gcaagagggg gtggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 4622 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4622 His Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Ser Arg Ser Ile Ala Arg 20 25 30 Gly Gly Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4623 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4623 Cys Ala Arg Asp Lys Gly Trp Gly Asp Gly Met Asp Val Trp 1 5 10 <210> 4624 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4624 atctccatat acaattccaa gaacacgctg tatcttcaaa tgggcagcct gagagctgag 60 gacatggctg cgtattactg tgcgagagat aaagggtggg gggacggaat ggacgtctgg 120 ggccaaggg 129 <210> 4625 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4625 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Gly Ser 1 5 10 15 Leu Arg Ala Glu Asp Met Ala Ala Tyr Tyr Cys Ala Arg Asp Lys Gly 20 25 30 Trp Gly Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4626 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4626 atctccatac acaattccaa gaacacgctg tatcttcaaa tgggcagcct gagagctgag 60 gacatggctg cgtattactg tgcgagagat aaagggtggg gggacggaat ggacgtctgg 120 ggccaaggg 129 <210> 4627 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4627 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Gly Ser 1 5 10 15 Leu Arg Ala Glu Asp Met Ala Ala Tyr Tyr Cys Ala Arg Asp Lys Gly 20 25 30 Trp Gly Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4628 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4628 atctccagag acaattccaa gaacacgctg tatcttcaaa tgggcagcct gagagctgag 60 gacatggctg cgtattactg tgcgagagat aaagggtggg gggacggaat ggacgtctgg 120 ggccaaggg 129 <210> 4629 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4629 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Gly Ser 1 5 10 15 Leu Arg Ala Glu Asp Met Ala Ala Tyr Tyr Cys Ala Arg Asp Lys Gly 20 25 30 Trp Gly Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4630 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4630 Cys Ala Lys Ser Ser Pro Thr Val Thr Asn Asn Trp Phe Asp Pro Trp 1 5 10 15 <210> 4631 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4631 agagacaatt ccaagaacac actgtatctg caaatgaacg gcctgagagc cggggacacg 60 gccatatatt actgtgcgaa atcaagtcca acggtgacta acaactggtt cgacccctgg 120 ggccaggga 129 <210> 4632 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4632 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Gly Leu Arg 1 5 10 15 Ala Gly Asp Thr Ala Ile Tyr Tyr Cys Ala Lys Ser Ser Pro Thr Val 20 25 30 Thr Asn Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4633 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4633 agagacaatt ccaagaacac actgtatctg caaatgaaca gcctgagagc cggggacacg 60 gccatatatt actgtgcgaa atcaagtcca acggtgacta acaactggtt cgacccctgg 120 ggccaggga 129 <210> 4634 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4634 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Gly Asp Thr Ala Ile Tyr Tyr Cys Ala Lys Ser Ser Pro Thr Val 20 25 30 Thr Asn Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4635 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4635 agagacaatt ccaagaacac actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccatatatt actgtgcgaa atcaagtcca acggtgacta acaactggtt cgacccctgg 120 ggccaggga 129 <210> 4636 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4636 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Lys Ser Ser Pro Thr Val 20 25 30 Thr Asn Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4637 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4637 Cys Ala Lys Asp Tyr Gly Ser Ser Trp Phe Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 4638 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4638 atatataatt ccaacaacac gctgtatctg caaatgaacc gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agattacggc agcagctggt tctactactt tgactactgg 120 ggccaggga 129 <210> 4639 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4639 Ile Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Arg Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Tyr Gly Ser Ser 20 25 30 Trp Phe Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4640 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4640 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agattacggc agcagctggt tctactactt tgactactgg 120 ggccaggga 129 <210> 4641 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4641 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Tyr Gly Ser Ser 20 25 30 Trp Phe Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4642 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4642 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccatatatt actgtgcgaa agattacggc agcagctggt tctactactt tgactactgg 120 ggccaggga 129 <210> 4643 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4643 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Lys Asp Tyr Gly Ser Ser 20 25 30 Trp Phe Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4644 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4644 Cys Ala Asn Gly Ile Ala Ala Arg Gly Thr Asp Tyr Trp 1 5 10 <210> 4645 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4645 accatctcca tatataattc caagaacacg ctgtatctgc aaatgagcag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaat ggaatagcag cacgtggtac cgactactgg 120 ggccaggga 129 <210> 4646 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4646 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Ser 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Asn Gly Ile 20 25 30 Ala Ala Arg Gly Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4647 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4647 accatctcca tacataattc caagaacacg ctgtatctgc aaatgagcag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaat ggaatagcag cacgtggtac cgactactgg 120 ggccaggga 129 <210> 4648 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4648 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Ser 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Asn Gly Ile 20 25 30 Ala Ala Arg Gly Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4649 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4649 accatctcca gagataattc caagaacacg ctgtatctgc aaatgagcag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaat ggaatagcag cacgtggtac cgactactgg 120 ggccaggga 129 <210> 4650 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4650 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Ser 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Asn Gly Ile 20 25 30 Ala Ala Arg Gly Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4651 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4651 Cys Ala Lys Asp Glu Asp Ser Gly Ser Gly Val Gly Gly Met Asp Val 1 5 10 15 Trp <210> 4652 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4652 gacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggct 60 gtgtattact gtgcgaaaga cgaagattcg gggagtggag tggggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4653 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4653 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Glu Asp Ser Gly Ser 20 25 30 Gly Val Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4654 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4654 gacaattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggct 60 gtgtattact gtgcgaaaga cgaagattcg gggagtggag tggggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4655 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4655 Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Glu Asp Ser Gly Ser 20 25 30 Gly Val Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4656 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4656 cacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggct 60 gtgtattact gtgcgaaaga cgaagattcg gggagtggag tggggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4657 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4657 His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Glu Asp Ser Gly Ser 20 25 30 Gly Val Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4658 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4658 Cys Ala Lys Asp Arg Arg Gly Val Arg Gly Val Ile Pro Ser Tyr Phe 1 5 10 15 Asp Tyr Trp <210> 4659 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4659 gccaagaact ccctgtatct gcaaatgaac agtctgagag ctgaggacac ggccttgtat 60 tactgtgcaa aagatagacg aggggttcgg ggagttattc ctagttactt tgactactgg 120 ggccagggg 129 <210> 4660 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4660 Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Arg Arg Gly Val Arg Gly Val 20 25 30 Ile Pro Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4661 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4661 gccaagaact ccctgtatct gcaaatgaac agtctgagag ctgaggacac ggccttgtat 60 tactgtgcaa aagatagacg aggggttcgg ggagttattc ctagttactt tgactactgg 120 ggccaggga 129 <210> 4662 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4662 gccaagaact ccctgtatct gaaaatgaac agtctgagag ctgaggacac ggccttttat 60 tactgtgcaa aagatagacg aggggttcgg ggagttattc ctagttactt tgactactgg 120 ggccaggga 129 <210> 4663 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4663 Ala Lys Asn Ser Leu Tyr Leu Lys Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Phe Tyr Tyr Cys Ala Lys Asp Arg Arg Gly Val Arg Gly Val 20 25 30 Ile Pro Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4664 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4664 Cys Ala Arg Ala Gly Val Trp Val Arg Gly Val Met Pro Arg Gln Arg 1 5 10 15 Glu Leu Asp Tyr Trp 20 <210> 4665 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4665 tgcacagtct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagcgg gggtttgggt tcggggagtt atgccccgcc agagagaact tgactactgg 120 ggccaggga 129 <210> 4666 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4666 Cys Thr Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Ala Gly Val Trp Val Arg Gly Val Met Pro 20 25 30 Arg Gln Arg Glu Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4667 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4667 tgcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagcgg gggtttgggt tcggggagtt atgccccgcc agagagaact tgactactgg 120 ggccaggga 129 <210> 4668 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4668 Cys Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Ala Gly Val Trp Val Arg Gly Val Met Pro 20 25 30 Arg Gln Arg Glu Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4669 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4669 agcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagcgg gggtttgggt tcggggagtt atgccccgcc agagagaact tgactactgg 120 ggccaggga 129 <210> 4670 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4670 Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Ala Gly Val Trp Val Arg Gly Val Met Pro 20 25 30 Arg Gln Arg Glu Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 4671 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4671 Cys Ala Thr Tyr Ser Gly Ser Ser His Tyr Trp 1 5 10 <210> 4672 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4672 cggttcacca tctccagata taattccaag aacacgctgt atctgcaaat gaagagcctg 60 agagccgagg acacggccgt atattactgt gcgacatata gtgggagctc tcactactgg 120 ggccaggga 129 <210> 4673 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4673 Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Lys Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr 20 25 30 Tyr Ser Gly Ser Ser His Tyr Trp Gly Gln Gly 35 40 <210> 4674 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4674 cggttcacca tctccagaga taattccaag aacacgctgt atctgcaaat gaagagcctg 60 agagccgagg acacggccgt atattactgt gcgacatata gtgggagctc tcactactgg 120 ggccaggga 129 <210> 4675 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4675 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Lys Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr 20 25 30 Tyr Ser Gly Ser Ser His Tyr Trp Gly Gln Gly 35 40 <210> 4676 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4676 cggttcacca tctccagaca taataccaag aacacgctgt atctgcaaat gaagagcctg 60 agagccgagg acacggccgt atattactgt gcgacatata gtgggagctc tcactactgg 120 ggccaggga 129 <210> 4677 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4677 Arg Phe Thr Ile Ser Arg His Asn Thr Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Lys Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr 20 25 30 Tyr Ser Gly Ser Ser His Tyr Trp Gly Gln Gly 35 40 <210> 4678 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4678 Cys Ala Arg Asp Leu Glu Thr Asp Thr Phe Asp Tyr Trp 1 5 10 <210> 4679 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4679 accatctcca gagacaacgc caggaacacc ttatatctgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtgtatta ctgtgcaaga gatctggaga ctgatacctt tgactactgg 120 ggccaggga 129 <210> 4680 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4680 Thr Ile Ser Arg Asp Asn Ala Arg Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu 20 25 30 Glu Thr Asp Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4681 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4681 accatctcca gagacaacgc caagaacacg ctgtatctgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtgtatta ctgtgcaagg gatctggaga ctgatacctt tgactactgg 120 ggccaggga 129 <210> 4682 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4682 Thr Ile Ser Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu 20 25 30 Glu Thr Asp Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4683 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4683 accatctcca gagacaacgc caagaacacg ctgtatctgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtgtatta ctgtgcaaga gatctggaga ctgatacctt tgactactgg 120 ggccaggga 129 <210> 4684 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4684 Cys Thr Thr Pro Phe Phe Arg Val Pro Gln Ala Trp 1 5 10 <210> 4685 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4685 ttcaccatct caagagatga ttcaaataat attgtgtttc tgcaaatgaa cagcctgaaa 60 accgaggaca cagccgtgta ttactgtacc acccctttct tccgggtgcc ccaggcctgg 120 ggccaggga 129 <210> 4686 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4686 Phe Thr Ile Ser Arg Asp Asp Ser Asn Asn Ile Val Phe Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Pro 20 25 30 Phe Phe Arg Val Pro Gln Ala Trp Gly Gln Gly 35 40 <210> 4687 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4687 ttcaccatct caagagatga ttcaaataat attgtgtttc tgcaaatgaa cagcctgaaa 60 accgaggaca cagccgcgta ttactgtacc acccctttct tccgggtgcc ccaggcctgg 120 ggccaggga 129 <210> 4688 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4688 Phe Thr Ile Ser Arg Asp Asp Ser Asn Asn Ile Val Phe Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Thr Glu Asp Thr Ala Ala Tyr Tyr Cys Thr Thr Pro 20 25 30 Phe Phe Arg Val Pro Gln Ala Trp Gly Gln Gly 35 40 <210> 4689 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4689 ttcaccatct caagagatga ttcaaataat attgtgtttc cgcaaatgaa cagcctgaaa 60 accgaggaca cagccgcgta ttactgtacc acccctttct tccgggtgcc ccaggcctgg 120 ggccaggga 129 <210> 4690 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4690 Phe Thr Ile Ser Arg Asp Asp Ser Asn Asn Ile Val Phe Pro Gln Met 1 5 10 15 Asn Ser Leu Lys Thr Glu Asp Thr Ala Ala Tyr Tyr Cys Thr Thr Pro 20 25 30 Phe Phe Arg Val Pro Gln Ala Trp Gly Gln Gly 35 40 <210> 4691 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4691 Cys Ala Arg Glu Gly Gly Thr Ile Phe Gly Trp Gly Met Asp Val Trp 1 5 10 15 <210> 4692 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4692 tgggacacat ccgcgagtac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 tctgtctatt actgtgcgag agaggggggt acgatttttg ggtggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4693 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4693 Trp Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ser Val Tyr Tyr Cys Ala Arg Glu Gly Gly Thr Ile 20 25 30 Phe Gly Trp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4694 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4694 tgggacacat ccgcgagaac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 tctgtctatt actgtgcgag agaggggggt acgatttttg ggtggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4695 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4695 Trp Asp Thr Ser Ala Arg Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ser Val Tyr Tyr Cys Ala Arg Glu Gly Gly Thr Ile 20 25 30 Phe Gly Trp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4696 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4696 agggacacat ccgcgagtac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 tctgtctatt actgtgcgag agaggggggt acgatttttg ggtggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4697 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4697 Arg Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ser Val Tyr Tyr Cys Ala Arg Glu Gly Gly Thr Ile 20 25 30 Phe Gly Trp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4698 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4698 Cys Ala Arg Asp Glu Ser Ser Ser Ser Leu Asn Trp Phe Asp Pro Trp 1 5 10 15 <210> 4699 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4699 tgggacacat ccgcgagcat agtctacatg gaactgagca gcctgagatc tgaagacacg 60 gctgtatatt actgtgcgag agacgaaagc agctcgtccc tgaactggtt cgacccctgg 120 ggccaggga 129 <210> 4700 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4700 Trp Asp Thr Ser Ala Ser Ile Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Glu Ser Ser Ser 20 25 30 Ser Leu Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4701 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4701 agggacacat ccgcgagcat agtctacatg gaactgagca gcctgagatc tgaagacacg 60 gctgtatatt actgtgcgag agacgaaagc agctcgtccc tgaactggtt cgacccctgg 120 ggccaggga 129 <210> 4702 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4702 Arg Asp Thr Ser Ala Ser Ile Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Glu Ser Ser Ser 20 25 30 Ser Leu Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4703 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4703 agggacacat ccgcgagcac agtctacatg gacctgagca gcctgagatc tgaagacacg 60 gctgtttatt actgtgcgag agacgaaagc agttcgtccc tgaattggtt cgacccctgg 120 ggccaggga 129 <210> 4704 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4704 Arg Asp Thr Ser Ala Ser Thr Val Tyr Met Asp Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Glu Ser Ser Ser 20 25 30 Ser Leu Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4705 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4705 Cys Ala Arg Leu Leu Gly Gly Gly Gly Gly Gln Thr Trp 1 5 10 <210> 4706 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4706 atcatctcca tacacaacgc caagaacacg ctgtatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg gggggggagg tcagacttgg 120 ggccaggga 129 <210> 4707 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4707 Ile Ile Ser Ile His Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu 20 25 30 Gly Gly Gly Gly Gly Gln Thr Trp Gly Gln Gly 35 40 <210> 4708 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4708 atcatctcca gagacaacgc caagaacacg ctgtatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg gggggggagg tcagacttgg 120 ggccaggga 129 <210> 4709 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4709 Ile Ile Ser Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu 20 25 30 Gly Gly Gly Gly Gly Gln Thr Trp Gly Gln Gly 35 40 <210> 4710 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4710 atcatctcca gacacaacgc caagaacacg ctgtatttgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtctatta ctgtgcaaga ctcctgggtg gggggggagg tcagacttgg 120 ggccaggga 129 <210> 4711 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4711 Ile Ile Ser Arg His Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu 20 25 30 Gly Gly Gly Gly Gly Gln Thr Trp Gly Gln Gly 35 40 <210> 4712 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4712 Cys Ala Arg Trp Ile Pro Met Val His Trp Pro Asn Asp Ala Phe Asp 1 5 10 15 Ile Trp <210> 4713 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4713 acctccatat gcacagccta cttggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagatggat ccctatggtt cattggccaa atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4714 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4714 Thr Ser Ile Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Trp Ile Pro Met Val His Trp 20 25 30 Pro Asn Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4715 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4715 acctccatat gcacagccta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagatggat ccctatggtt cattggccaa atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4716 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4716 Thr Ser Ile Cys Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Trp Ile Pro Met Val His Trp 20 25 30 Pro Asn Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4717 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4717 acctccataa gcacagccta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagatggat ccctatggtt cattggccaa atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4718 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4718 Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Trp Ile Pro Met Val His Trp 20 25 30 Pro Asn Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4719 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4719 Cys Ala Arg Arg Gly Ser Gly Ser Pro Ala Thr Gly Ile Asp Tyr Trp 1 5 10 15 <210> 4720 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4720 tgggacacgc cccagagcac agtctacatg gacctgagca gcctcagaac taacgacacg 60 gccatgtttt actgtgcgag aaggggatcg gggagcccag ctaccggcat tgactactgg 120 ggccaggga 129 <210> 4721 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4721 Trp Asp Thr Pro Gln Ser Thr Val Tyr Met Asp Leu Ser Ser Leu Arg 1 5 10 15 Thr Asn Asp Thr Ala Met Phe Tyr Cys Ala Arg Arg Gly Ser Gly Ser 20 25 30 Pro Ala Thr Gly Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4722 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4722 agggacacgt cccagagcac agtctacatg gacctgagca gcctcagaac tgacgacacg 60 gccatgtttt actgtgcgag aaggggatcg gggagcccag ctaccggcat tgactactgg 120 ggccaggga 129 <210> 4723 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4723 Arg Asp Thr Ser Gln Ser Thr Val Tyr Met Asp Leu Ser Ser Leu Arg 1 5 10 15 Thr Asp Asp Thr Ala Met Phe Tyr Cys Ala Arg Arg Gly Ser Gly Ser 20 25 30 Pro Ala Thr Gly Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4724 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4724 agggacacgt cccagagcac agtctacatg gacctgagca gcctcagaac taacgacacg 60 gccatgtttt actgtgcgag aaggggatcg gggagcccag ctaccggcat tgactactgg 120 ggccaggga 129 <210> 4725 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4725 Arg Asp Thr Ser Gln Ser Thr Val Tyr Met Asp Leu Ser Ser Leu Arg 1 5 10 15 Thr Asn Asp Thr Ala Met Phe Tyr Cys Ala Arg Arg Gly Ser Gly Ser 20 25 30 Pro Ala Thr Gly Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4726 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4726 Cys Ala Lys Glu Val Arg Glu Arg Trp Pro Ser Gly Met Asp Val Trp 1 5 10 15 <210> 4727 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4727 ttatataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agaggtccgg gaacggtggc ccagcggtat ggacgtctgg 120 ggccaaggg 129 <210> 4728 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4728 Leu Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Val Arg Glu Arg 20 25 30 Trp Pro Ser Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4729 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4729 ttagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agaggtccgg gaacggtggc ccagcggtat ggacgtctgg 120 ggccaaggg 129 <210> 4730 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4730 Leu Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Val Arg Glu Arg 20 25 30 Trp Pro Ser Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4731 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4731 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agaggtccgg gaacggtggc ccagcggtat ggacgtctgg 120 ggccaaggg 129 <210> 4732 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4732 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Val Arg Glu Arg 20 25 30 Trp Pro Ser Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4733 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4733 Cys Ala Arg Asp Phe Ser Ser Ser Trp Tyr Ser Tyr Phe Gln His Trp 1 5 10 15 <210> 4734 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4734 tgggacacgt ccacgagcac tgtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agattttagc agcagctggt atagctactt ccagcactgg 120 ggccagggc 129 <210> 4735 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4735 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Phe Ser Ser Ser 20 25 30 Trp Tyr Ser Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 4736 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4736 tgggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agattttagc agcagctggt atagctactt ccagcactgg 120 ggccagggc 129 <210> 4737 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4737 agggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agattttagc agcagctggt atagctactt ccagcactgg 120 ggccagggc 129 <210> 4738 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4738 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Phe Ser Ser Ser 20 25 30 Trp Tyr Ser Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 4739 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4739 Cys Ala Arg Gly Val Tyr Gly Ser Gly Asp Asp Trp 1 5 10 <210> 4740 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4740 ttcaccatct ccagagacaa ttccaagaac acgctgtatc ttcaaatgaa cagcctgaga 60 gccgaggaca cggccgtgta ttactgtgcg agaggggtgt atggttcggg agacgattgg 120 ggccaggga 129 <210> 4741 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4741 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly 20 25 30 Val Tyr Gly Ser Gly Asp Asp Trp Gly Gln Gly 35 40 <210> 4742 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4742 ttcaccatct ccagacacaa ttccaagaac acgctgtatc ttcaaatgaa cagcctgaga 60 gccgaggaca cggccgtgta ttactgtgcg agaggggtgt atggttcggg agacgattgg 120 ggccaggga 129 <210> 4743 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4743 Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly 20 25 30 Val Tyr Gly Ser Gly Asp Asp Trp Gly Gln Gly 35 40 <210> 4744 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4744 ttcaccatct ccagacacaa ttccaagaac acgctgtatc ttcaaatcaa cagcctgaga 60 gccgaggaca cggccgtgta ttactgtgcg agaggggtgt atggttcggg agacgattgg 120 ggccaggga 129 <210> 4745 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4745 Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly 20 25 30 Val Tyr Gly Ser Gly Asp Asp Trp Gly Gln Gly 35 40 <210> 4746 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4746 Cys Ala Lys Gly Ala Ile Ala Val Ala Gly Met Thr Asp Tyr Trp 1 5 10 15 <210> 4747 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4747 tccattaata attccaagaa cacgctgaat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggggct atagcagtgg ctggtatgac tgactactgg 120 ggccaggga 129 <210> 4748 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4748 Ser Ile Asn Asn Ser Lys Asn Thr Leu Asn Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Ala Ile Ala 20 25 30 Val Ala Gly Met Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4749 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4749 tccagagatg attcaaagaa cacggcgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggggct atagcagtgg ctggtatgac tgactactgg 120 ggccaggga 129 <210> 4750 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4750 Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Ala Ile Ala 20 25 30 Val Ala Gly Met Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4751 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4751 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggggct atagcagtgg ctggtatgac tgactactgg 120 ggccaggga 129 <210> 4752 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4752 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Ala Ile Ala 20 25 30 Val Ala Gly Met Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4753 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4753 Cys Thr Arg His Trp Asp Ser Gly Tyr Asp Ser Met Asp Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 4754 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4754 aacacggcgt atctgcaaat gaacagcctg aaaaccgagg acacggccgt gtattactgt 60 actagacatt gggatagtgg ctacgattcg atggactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4755 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4755 Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Thr Arg His Trp Asp Ser Gly Tyr Asp Ser Met Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4756 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4756 tacacggcgt atctgcaaat gaacagcctg aaaaccgagg acacggccgt gtattactgt 60 actagacatt gggatagtgg ctacgattcg atggactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4757 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4757 Tyr Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Thr Arg His Trp Asp Ser Gly Tyr Asp Ser Met Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4758 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4758 aacacggcgt atctgcaaat caacagcctg aaaaccgagg acacggccgt gtattactgt 60 actagacatt gggatagtgg ctacgattcg atggactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4759 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4759 Asn Thr Ala Tyr Leu Gln Ile Asn Ser Leu Lys Thr Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Thr Arg His Trp Asp Ser Gly Tyr Asp Ser Met Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4760 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4760 Cys Ala His Arg Arg Asp Asn Ser Trp Tyr Asp Tyr Trp 1 5 10 <210> 4761 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4761 accatcacca cggacacctc caaaaagcag gtggtcctta caatgaccaa catggaccct 60 gtggacacag ccacatatta ctgtgcacac agacgtgaca atagctggta tgactactgg 120 ggcctggga 129 <210> 4762 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4762 Thr Ile Thr Thr Asp Thr Ser Lys Lys Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg 20 25 30 Asp Asn Ser Trp Tyr Asp Tyr Trp Gly Leu Gly 35 40 <210> 4763 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4763 accatcacca cggacacctc caaaaaccag gtagtcctta caatgaccaa catggaccct 60 gtggacacag ccacatatta ctgtgcacac agacgtgaca atagctggta tgactactgg 120 ggcctggga 129 <210> 4764 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4764 Thr Ile Thr Thr Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg 20 25 30 Asp Asn Ser Trp Tyr Asp Tyr Trp Gly Leu Gly 35 40 <210> 4765 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4765 accatcacca cggacacctc caaaaaccag gtagtcctta caatgaccaa catggaccct 60 gtggacacag ccacatatta ctgtgcacac agacgtgaca atagctggta tgactactgg 120 ggccagggc 129 <210> 4766 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4766 Thr Ile Thr Thr Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg 20 25 30 Asp Asn Ser Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4767 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4767 Cys Ala Lys Glu Gly Lys Ile Val Gly Ala Thr Met Pro Phe Asp Tyr 1 5 10 15 Trp <210> 4768 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4768 gacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga ggggaagata gtgggagcta ctatgccttt tgactactgg 120 ggccaggga 129 <210> 4769 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4769 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Gly Lys Ile Val Gly 20 25 30 Ala Thr Met Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4770 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4770 gacaatccca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga ggggaagata gtgggagcta ctatgccttt tgactactgg 120 ggccaggga 129 <210> 4771 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4771 Asp Asn Pro Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Gly Lys Ile Val Gly 20 25 30 Ala Thr Met Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4772 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4772 gaaaattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga ggggaagata gtgggagcta ctatgccttt tgactactgg 120 ggccaggga 129 <210> 4773 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4773 Glu Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Gly Lys Ile Val Gly 20 25 30 Ala Thr Met Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4774 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4774 Cys Ala Lys Asp Leu Ser Asn Ser Gly Ala Thr Glu Tyr Trp 1 5 10 <210> 4775 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4775 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagac ctatcaaata gtggtgctac tgaatactgg 120 ggccaggga 129 <210> 4776 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4776 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Ser 20 25 30 Asn Ser Gly Ala Thr Glu Tyr Trp Gly Gln Gly 35 40 <210> 4777 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4777 atctccatac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagac ctatcaaata gtggtgctac tgaatactgg 120 ggccaggga 129 <210> 4778 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4778 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Ser 20 25 30 Asn Ser Gly Ala Thr Glu Tyr Trp Gly Gln Gly 35 40 <210> 4779 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4779 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagac ctatcaaata gtggtgctac tgaatactgg 120 ggccaggga 129 <210> 4780 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4780 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Ser 20 25 30 Asn Ser Gly Ala Thr Glu Tyr Trp Gly Gln Gly 35 40 <210> 4781 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4781 Cys Ala Arg Val Arg Ser Tyr Asp Ser Thr Ala Tyr Asp Glu Pro Leu 1 5 10 15 Asp Ala Leu Asp Ile Trp 20 <210> 4782 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4782 acagcctact tggagttgcg ctgcctgaga tctgaagaca cggctgtata ttactgtgcg 60 agagttcggt cctatgatag tactgcgtat gacgaacccc ttgatgctct tgatatctgg 120 ggccaaggg 129 <210> 4783 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4783 Thr Ala Tyr Leu Glu Leu Arg Cys Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Val Arg Ser Tyr Asp Ser Thr Ala Tyr Asp Glu 20 25 30 Pro Leu Asp Ala Leu Asp Ile Trp Gly Gln Gly 35 40 <210> 4784 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4784 acagcctact tggagttgcg cagcctgaga tctgaagaca cggctgtata ttactgtgcg 60 agagttcggt cctatgatag tactgcgtat gacgaacccc ttgatgctct tgatatctgg 120 ggccaaggg 129 <210> 4785 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4785 Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Val Arg Ser Tyr Asp Ser Thr Ala Tyr Asp Glu 20 25 30 Pro Leu Asp Ala Leu Asp Ile Trp Gly Gln Gly 35 40 <210> 4786 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4786 acagcctaca tggagttgcg cagcctgaga tctgaagaca cggctgtata ttactgtgcg 60 agagttcggt cctatgatag tactgcgtat gacgaacccc ttgatgctct tgatatctgg 120 ggccaaggg 129 <210> 4787 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4787 Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Val Arg Ser Tyr Asp Ser Thr Ala Tyr Asp Glu 20 25 30 Pro Leu Asp Ala Leu Asp Ile Trp Gly Gln Gly 35 40 <210> 4788 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4788 Cys Ala Lys Ala Arg Gly Val Gly Gly Pro Phe Asp Tyr Trp 1 5 10 <210> 4789 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4789 atctccatag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggctg tgtattactg tgcgaaagcc cggggggtgg gcgggccgtt tgactactgg 120 ggccaggga 129 <210> 4790 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4790 Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Arg Gly 20 25 30 Val Gly Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4791 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4791 atctccatac acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggctg tgtattactg tgcgaaagcc cggggggtgg gcgggccgtt tgactactgg 120 ggccaggga 129 <210> 4792 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4792 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Arg Gly 20 25 30 Val Gly Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4793 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4793 atctccagag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggctg tgtattactg tgcgaaagcc cggggggtgg gcgggccgtt tgactactgg 120 ggccaggga 129 <210> 4794 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4794 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Arg Gly 20 25 30 Val Gly Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4795 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4795 Cys Thr Arg Tyr Gly Asp Thr Arg Asp Trp Val Phe Asp Leu Trp 1 5 10 15 <210> 4796 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4796 ccagagatga ttcagagaac cacggcgtat ctgcaaatga acagcctgaa gaccgaggac 60 acggccgtgt attactgtac tagatacggt gacaccaggg actgggtctt cgatctgtgg 120 ggccgtggc 129 <210> 4797 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4797 Pro Glu Met Ile Gln Arg Thr Thr Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Tyr Gly Asp Thr 20 25 30 Arg Asp Trp Val Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4798 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4798 tccagagatt attcagacaa cacggcgtat ctgcaaatga acagcctgaa gaccgaggac 60 acggccgtgt attactgtac tagatacggt gacaccaggg actgggtctt cgatctgtgg 120 ggccgtggc 129 <210> 4799 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4799 Ser Arg Asp Tyr Ser Asp Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Tyr Gly Asp Thr 20 25 30 Arg Asp Trp Val Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4800 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4800 tccagagatg attcagagaa cacggcgtat ctgcaaatga acagcctgaa gaccgaggac 60 acggccgtgt attactgtac tagatacggt gacaccaggg actgggtctt cgatctgtgg 120 ggccgtggc 129 <210> 4801 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4801 Ser Arg Asp Asp Ser Glu Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Tyr Gly Asp Thr 20 25 30 Arg Asp Trp Val Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4802 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4802 Cys Ala His Thr Pro Gly Gly Ser Glu Leu Arg Glu Gly Ile Asp Tyr 1 5 10 15 Trp <210> 4803 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4803 gacacctcca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacac ccccggtggc tctgaattac gggaggggat tgactactgg 120 ggccaggga 129 <210> 4804 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4804 Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Thr Pro Gly Gly Ser Glu 20 25 30 Leu Arg Glu Gly Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4805 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4805 ggacacctcc aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacac ccccggtggc tctgaattac gggaggggat tgactactgg 120 ggccaggga 129 <210> 4806 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4806 Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Thr Pro Gly Gly Ser Glu 20 25 30 Leu Arg Glu Gly Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4807 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4807 ggacacctcc aaaaaccagg tggtccttca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacac ccccggtggc tctgaattac gggaggggat tgactactgg 120 ggccaggga 129 <210> 4808 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4808 Gly His Leu Gln Lys Pro Gly Gly Pro Ser Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Thr Pro Gly Gly Ser Glu 20 25 30 Leu Arg Glu Gly Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 4809 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4809 Cys Ala Arg Tyr His Ile Leu Thr Gly Gln Tyr Met Asp Tyr Tyr Tyr 1 5 10 15 Tyr Gly Leu Asp Val Trp 20 <210> 4810 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4810 tatctgcatc tgcagatgag cagcctgaga gccggcgaca cggccgtata ttattgtgcg 60 aggtaccata ttttgactgg tcagtatatg gactactact actacggtct ggacgtctgg 120 ggccaaggg 129 <210> 4811 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4811 Tyr Leu His Leu Gln Met Ser Ser Leu Arg Ala Gly Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Tyr His Ile Leu Thr Gly Gln Tyr Met Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 4812 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4812 actctgcatc tgcagatgag cagcctgaga gccggcgaca cggccgtata ttattgtgcg 60 aggtaccata ttttgactgg tcagtatatg gactactact actacggtct ggacgtctgg 120 ggccaaggg 129 <210> 4813 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4813 Thr Leu His Leu Gln Met Ser Ser Leu Arg Ala Gly Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Tyr His Ile Leu Thr Gly Gln Tyr Met Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 4814 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4814 actatgcatc tgctgatgag cagcctgaga gccggcgaca cggccgtata ttattgtgcg 60 aggtaccata ttttgactgg tcagtatatg gactactact actacggtct ggacgtctgg 120 ggccaaggg 129 <210> 4815 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4815 Thr Met His Leu Leu Met Ser Ser Leu Arg Ala Gly Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Tyr His Ile Leu Thr Gly Gln Tyr Met Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 4816 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4816 Cys Ala Thr Asn Ile Ala Ala Ala Gly Thr Asp Ala Phe Asp Ile Trp 1 5 10 15 <210> 4817 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4817 gaggacacat ctacagacac agcctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcaac aaatatagca gcagctggta ctgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4818 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4818 Glu Asp Thr Ser Thr Asp Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Asn Ile Ala Ala Ala 20 25 30 Gly Thr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4819 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4819 gaggacacat ctacagacac agcctacacg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtact actgtgcaac aaatatagca gcagctggta ctgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4820 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4820 Glu Asp Thr Ser Thr Asp Thr Ala Tyr Thr Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Asn Ile Ala Ala Ala 20 25 30 Gly Thr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4821 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4821 gaggacacat atacagacac agcctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcaac aaatatagca gcagctggta ctgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 4822 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4822 Glu Asp Thr Tyr Thr Asp Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Asn Ile Ala Ala Ala 20 25 30 Gly Thr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4823 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4823 Cys Ala Lys Asp Gly Arg Leu Ile Ala Ala Ala Gly Arg Glu Trp Tyr 1 5 10 15 Trp Tyr Phe Asp Leu Trp 20 <210> 4824 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4824 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagatggga ggcttatagc agcagctggt agagagtggt actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4825 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4825 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Gly Arg Leu Ile Ala Ala Ala Gly Arg Glu 20 25 30 Trp Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4826 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4826 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagatggga ggcttatagc agcagccggt agagagtggt actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4827 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4827 aagatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagatggga ggcttatagc agcagctggt agagagtggt actggtactt cgatctctgg 120 ggccgtggc 129 <210> 4828 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4828 Lys Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Gly Arg Leu Ile Ala Ala Ala Gly Arg Glu 20 25 30 Trp Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4829 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4829 Cys Ala Lys Asp Thr Gly Asn Trp 1 5 <210> 4830 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4830 gtgaagggcc ggttcaccat ctccagatat aattccaaga acacgctgta tctgcaaatt 60 aacagcctga gagccgagga cacggccgta tattactgtg cgaaagatac gggcaactgg 120 ggccaggga 129 <210> 4831 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4831 Val Lys Gly Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu 1 5 10 15 Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 20 25 30 Cys Ala Lys Asp Thr Gly Asn Trp Gly Gln Gly 35 40 <210> 4832 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4832 gtgaagggcc ggttcaccat ctccagatat aattccaaga acacgctgta tctgaaaatg 60 aacagcctga gagccgagga cacggccgta tattactgtg cgaaagatac gggcaactgg 120 ggccaggga 129 <210> 4833 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4833 Val Lys Gly Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu 1 5 10 15 Tyr Leu Lys Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 20 25 30 Cys Ala Lys Asp Thr Gly Asn Trp Gly Gln Gly 35 40 <210> 4834 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4834 gtgaagggcc ggttcaccat ctccagagat aattccaaga acacgctgta tctgcaaatg 60 aacagcctga gagccgagga cacggccgta tattactgtg cgaaagatac gggcaactgg 120 ggccaggga 129 <210> 4835 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4835 Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu 1 5 10 15 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 20 25 30 Cys Ala Lys Asp Thr Gly Asn Trp Gly Gln Gly 35 40 <210> 4836 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4836 Cys Ala Lys Gly Tyr Thr Ser Gly Trp Tyr Asp Tyr Trp 1 5 10 <210> 4837 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4837 accatctcca tacacaattc caagagcacg ctgcatctgc aaatgagcag cctgagagcc 60 gaggacacgg ccgtatattt ctgtgcgaag ggatatacga gtggctggta cgactactgg 120 ggccaggga 129 <210> 4838 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4838 Thr Ile Ser Ile His Asn Ser Lys Ser Thr Leu His Leu Gln Met Ser 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Phe Cys Ala Lys Gly Tyr 20 25 30 Thr Ser Gly Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4839 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4839 accatctcca gagacaattc caagagcacg ctgcatctgc aaatgagcag cctgagagcc 60 gaggacacgg ccgtatattt ctgtgcgaag ggatatacga gtggctggta cgactactgg 120 ggccaggga 129 <210> 4840 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4840 Thr Ile Ser Arg Asp Asn Ser Lys Ser Thr Leu His Leu Gln Met Ser 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Phe Cys Ala Lys Gly Tyr 20 25 30 Thr Ser Gly Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4841 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4841 aacatctcca tagacaattc caagagcacg ctgcatctgc aaatgagcag cctgagagcc 60 gaggacacgg ccgtatattt ctgtgcgaag ggatatacga gtggctggta cgactactgg 120 ggccaggga 129 <210> 4842 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4842 Asn Ile Ser Ile Asp Asn Ser Lys Ser Thr Leu His Leu Gln Met Ser 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Phe Cys Ala Lys Gly Tyr 20 25 30 Thr Ser Gly Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 4843 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4843 Cys Ala His Ile Asn Ser Glu Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 1 5 10 15 <210> 4844 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4844 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cattaacagc gagtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4845 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4845 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ile Asn Ser Glu Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4846 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4846 agggacacct ccaaaaacca ggtggtcctt acagtgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cattaacagc gagtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4847 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4847 Arg Asp Thr Ser Lys Asn Gln Val Val Leu Thr Val Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ile Asn Ser Glu Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4848 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4848 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cattaacagc gagtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4849 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4849 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ile Asn Ser Glu Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4850 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4850 Cys Ala Arg Glu Asn Ser Gly Tyr Gly Phe Asp Tyr Trp 1 5 10 <210> 4851 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4851 accatctcca gagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggggacacgg ctgtgtatta ctgtgcaaga gaaaatagtg gctacgggtt tgactactgg 120 ggccaggga 129 <210> 4852 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4852 Thr Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Asn 20 25 30 Ser Gly Tyr Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4853 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4853 aacatctcca tagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggggacacgg ctgtgtatta ctgtgcaaga gaaaatagtg gctacgggtt tgactactgg 120 ggccaggga 129 <210> 4854 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4854 Asn Ile Ser Ile Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Asn 20 25 30 Ser Gly Tyr Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4855 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4855 aacatctcca gagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggtgacacgg ctgtgtatta ctgtgcaaga gaaaatagtg gctacgggtt tgactactgg 120 ggccaggga 129 <210> 4856 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4856 Asn Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Asn 20 25 30 Ser Gly Tyr Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4857 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4857 Cys Ala Arg Gly Val Ser Ser Ser Trp Tyr Ala Trp Phe Asp Pro Trp 1 5 10 15 <210> 4858 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4858 tgggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag aggggttagc agcagctggt atgcttggtt cgacccctgg 120 ggccaggga 129 <210> 4859 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4859 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Val Ser Ser Ser 20 25 30 Trp Tyr Ala Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4860 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4860 tgggacacgc ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag aggggttagc agcagctggt atgcttggtt cgacccctgg 120 ggccaggga 129 <210> 4861 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4861 Trp Asp Thr Pro Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Val Ser Ser Ser 20 25 30 Trp Tyr Ala Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4862 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4862 agggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag aggggttagc agcagctggt atgcttggtt cgacccctgg 120 ggccaggga 129 <210> 4863 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4863 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Val Ser Ser Ser 20 25 30 Trp Tyr Ala Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4864 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4864 Cys Thr Thr Asp Ala Trp Asp Ile Val Val Val Pro Ala Ala Met His 1 5 10 15 Ala His Phe Asp Tyr Trp 20 <210> 4865 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4865 acgctgtatc tgcgaatgaa cagcctgaaa accgaggaca cagccgtgta ttactgtacc 60 acagatgctt gggatattgt agtagtacca gctgctatgc atgctcattt tgactactgg 120 ggccaggga 129 <210> 4866 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4866 Thr Leu Tyr Leu Arg Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Thr Thr Asp Ala Trp Asp Ile Val Val Val Pro Ala Ala 20 25 30 Met His Ala His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4867 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4867 acgctgtatc tgcaaatgaa cagcctgaaa accgaggaca cagccgtgta ttactgtacc 60 acagatgctt gggatattgt agtagtacca gctgctatgc atgctcattt tgactactgg 120 ggccaggga 129 <210> 4868 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4868 Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Thr Thr Asp Ala Trp Asp Ile Val Val Val Pro Ala Ala 20 25 30 Met His Ala His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4869 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4869 aagctgtatc tgcgaatgaa cagcctgaaa accgaggaca cagccgtgta ttactgtacc 60 acagatgctt gggatattgt agtagtacca gctgctatgc atgctcattt tgactactgg 120 ggccaggga 129 <210> 4870 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4870 Lys Leu Tyr Leu Arg Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Thr Thr Asp Ala Trp Asp Ile Val Val Val Pro Ala Ala 20 25 30 Met His Ala His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4871 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4871 Cys Val Val Ile Gly Val Gln Glu Gly Tyr Trp 1 5 10 <210> 4872 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4872 tggttcacca tctccagata tgattcaaag accacggcgt atctgcaaat gaacagcctg 60 aaacccgagg acacggccgt gtattactgt gtggtaatag gggtgcaaga aggctactgg 120 ggccaggga 129 <210> 4873 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4873 Trp Phe Thr Ile Ser Arg Tyr Asp Ser Lys Thr Thr Ala Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Lys Pro Glu Asp Thr Ala Val Tyr Tyr Cys Val Val 20 25 30 Ile Gly Val Gln Glu Gly Tyr Trp Gly Gln Gly 35 40 <210> 4874 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4874 tggttcacca tctccagata tgattcaaag accacggcgt atctgcaaat gaacagcctg 60 aaaaccgagg acacggccgt gtattactgt gtggtaatag gggtgcaaga aggctactgg 120 ggccaggga 129 <210> 4875 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4875 Trp Phe Thr Ile Ser Arg Tyr Asp Ser Lys Thr Thr Ala Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Val Val 20 25 30 Ile Gly Val Gln Glu Gly Tyr Trp Gly Gln Gly 35 40 <210> 4876 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4876 aggttcacca tctccagaga tgattcaaag accacggcgt atctgcaaat gaacagcctg 60 aaaaccgagg acacggccgt gtattactgt gtggtaatag gggtgcaaga aggctactgg 120 ggccaggga 129 <210> 4877 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4877 Arg Phe Thr Ile Ser Arg Asp Asp Ser Lys Thr Thr Ala Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Val Val 20 25 30 Ile Gly Val Gln Glu Gly Tyr Trp Gly Gln Gly 35 40 <210> 4878 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4878 Cys Ala Arg Asp Asp Ser Arg Ser Ala Phe Gly Glu Leu Leu Ser Gly 1 5 10 15 Leu Met Asp Val Trp 20 <210> 4879 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4879 tgcagagtct acttggagct gagcagcctg agatctgaag acacggccgt gtattattgt 60 gcgagagatg attctcgatc ggcgttcggg gagttattat cgggcctgat ggacgtctgg 120 ggccaaggg 129 <210> 4880 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4880 Cys Arg Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Asp Ser Arg Ser Ala Phe Gly Glu Leu 20 25 30 Leu Ser Gly Leu Met Asp Val Trp Gly Gln Gly 35 40 <210> 4881 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4881 tgcagagtct acatggagct gagcagcctg agatctgaag acacggccgt gtattattgt 60 gcgagagatg attctcgatc ggcgttcggg gagttattat cgggcctgat ggacgtctgg 120 ggccaaggg 129 <210> 4882 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4882 Cys Arg Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Asp Ser Arg Ser Ala Phe Gly Glu Leu 20 25 30 Leu Ser Gly Leu Met Asp Val Trp Gly Gln Gly 35 40 <210> 4883 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4883 agcagagtct acatggagct gagcagcctg agatctgaag acacggccgt gtattattgt 60 gcgagagatg attctcgatc ggcgttcggg gagttattat cgggcctgat ggacgtctgg 120 ggccaaggg 129 <210> 4884 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4884 Ser Arg Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Asp Ser Arg Ser Ala Phe Gly Glu Leu 20 25 30 Leu Ser Gly Leu Met Asp Val Trp Gly Gln Gly 35 40 <210> 4885 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4885 Cys Ala Arg Val Ser Leu Gly Thr Pro Glu Leu Gly Gly Val Glu Gly 1 5 10 15 Pro Phe Asp Tyr Trp 20 <210> 4886 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4886 tgcacagcct acttggagct gagcagcctg agatctgaag acacggctgt gtattactgt 60 gcgagagttt ccctagggac cccggagctg ggtggggtgg aggggccttt tgactactgg 120 ggccaggga 129 <210> 4887 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4887 Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Val Ser Leu Gly Thr Pro Glu Leu Gly Gly 20 25 30 Val Glu Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4888 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4888 tgcacagcct acatggagct gagcagcctg agatctgaag acacggctgt gtattactgt 60 gcgagagttt ccctagggac cccggagctg ggtggggtgg aggggccttt tgactactgg 120 ggccaggga 129 <210> 4889 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4889 Cys Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Val Ser Leu Gly Thr Pro Glu Leu Gly Gly 20 25 30 Val Glu Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4890 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4890 agcacagcct acatggagct gagcagcctg agatctgaag acacggctgt gtattactgt 60 gcgagagttt ccctagggac cccggagctg ggtggggtgg aggggccttt tgactactgg 120 ggccaggga 129 <210> 4891 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4891 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Val Ser Leu Gly Thr Pro Glu Leu Gly Gly 20 25 30 Val Glu Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4892 <211> 27 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4892 Cys Ala Lys Asp Lys Tyr Tyr Ser Ser Ser Trp Tyr Gly Arg Pro Pro 1 5 10 15 Thr Thr Asn Glu Ala Gly Gly Met Asp Val Trp 20 25 <210> 4893 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4893 ttgaacagcc tgagagccga ggacacggcc gtatattact gtgcgaaaga caagtactat 60 agcagcagct ggtacggacg accgccgacg actaacgagg cggggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4894 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4894 Leu Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 1 5 10 15 Asp Lys Tyr Tyr Ser Ser Ser Trp Tyr Gly Arg Pro Pro Thr Thr Asn 20 25 30 Glu Ala Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4895 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4895 ttcaacagcc tgagagccga ggacacggcc gtatattact gtgcgaaaga caagtactat 60 agcagcagct ggtacggacg accgccgacg actaacgagg cggggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4896 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4896 Phe Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 1 5 10 15 Asp Lys Tyr Tyr Ser Ser Ser Trp Tyr Gly Arg Pro Pro Thr Thr Asn 20 25 30 Glu Ala Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4897 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4897 atgaacagcc tgagagccga ggacacggcc gtatattact gtgcgaaaga caagtactat 60 agcagcagct ggtacggacg accgccgacg actaacgagg cggggggtat ggacgtctgg 120 ggccaaggg 129 <210> 4898 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4898 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 1 5 10 15 Asp Lys Tyr Tyr Ser Ser Ser Trp Tyr Gly Arg Pro Pro Thr Thr Asn 20 25 30 Glu Ala Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4899 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4899 Cys Ile Thr Thr Tyr Gly Tyr Ser Gly Tyr Asp His Gly Tyr Trp 1 5 10 15 <210> 4900 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4900 tcaagagatg attcaagaac cactgtctat ctgcaaatga acagcctgaa aagcgaggac 60 acaggcgtct attactgtat cacgacgtat ggatatagtg gctacgatca tggctactgg 120 ggccaggga 129 <210> 4901 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4901 Ser Arg Asp Asp Ser Arg Thr Thr Val Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Ser Glu Asp Thr Gly Val Tyr Tyr Cys Ile Thr Thr Tyr Gly Tyr 20 25 30 Ser Gly Tyr Asp His Gly Tyr Trp Gly Gln Gly 35 40 <210> 4902 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4902 tcaagagatg attcaaaaaa cacgctgtat ctgcaaatga acagcctgaa aagcgaggac 60 acaggcgtct attactgtat cacgacgtat ggatatagtg gctacgatca tggctactgg 120 ggccaggga 129 <210> 4903 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4903 Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Ser Glu Asp Thr Gly Val Tyr Tyr Cys Ile Thr Thr Tyr Gly Tyr 20 25 30 Ser Gly Tyr Asp His Gly Tyr Trp Gly Gln Gly 35 40 <210> 4904 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4904 tcaagagatg attcaaaaaa cacgctgtat ctgcaaatga acagcctgaa aaccgaggac 60 acagccgtgt attactgtat cacgacgtat ggatatagtg gctacgatca tggctactgg 120 ggccaggga 129 <210> 4905 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4905 Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ile Thr Thr Tyr Gly Tyr 20 25 30 Ser Gly Tyr Asp His Gly Tyr Trp Gly Gln Gly 35 40 <210> 4906 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4906 Cys Ala Arg Trp Gly Glu Ala Asn Ser Gly Tyr Asp Asp His Trp Phe 1 5 10 15 Asp Pro Trp <210> 4907 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4907 tccatcggca ccgcctacct gcagtggagc agcctgaagg cctcggacac cgccatgtat 60 tactgtgcga gatgggggga ggcaaatagc ggctacgatg atcactggtt cgacccctgg 120 ggccaggga 129 <210> 4908 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4908 Ser Ile Gly Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser Asp 1 5 10 15 Thr Ala Met Tyr Tyr Cys Ala Arg Trp Gly Glu Ala Asn Ser Gly Tyr 20 25 30 Asp Asp His Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4909 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4909 tccatcagca ccgcctacct gcagtggggc agcctgaagg cctcggacac cgccatgtat 60 tactgtgcga gatgggggga ggcaaatagt ggctacgatg atcactggtt tgacccctgg 120 ggccaggga 129 <210> 4910 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4910 Ser Ile Ser Thr Ala Tyr Leu Gln Trp Gly Ser Leu Lys Ala Ser Asp 1 5 10 15 Thr Ala Met Tyr Tyr Cys Ala Arg Trp Gly Glu Ala Asn Ser Gly Tyr 20 25 30 Asp Asp His Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4911 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4911 tccatcagca ccgcctacct gcagtggagc agcctgaagg cctcggacac cgccatgtat 60 tactgtgcga gatgggggga ggcaaatagt ggctacgatg atcactggtt cgacccctgg 120 ggccaggga 129 <210> 4912 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4912 Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser Asp 1 5 10 15 Thr Ala Met Tyr Tyr Cys Ala Arg Trp Gly Glu Ala Asn Ser Gly Tyr 20 25 30 Asp Asp His Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4913 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4913 Cys Thr Ser Leu Thr Leu Phe Gly Glu Leu Val Thr Trp 1 5 10 <210> 4914 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4914 accatctcca tagatcattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactagt ctaacactct tcggggagtt agtaacttgg 120 ggccaggga 129 <210> 4915 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4915 Thr Ile Ser Ile Asp His Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Leu Thr 20 25 30 Leu Phe Gly Glu Leu Val Thr Trp Gly Gln Gly 35 40 <210> 4916 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4916 accatctcca gagattattc aaagaacacg gcgtatctgc aaatgaacag ccttaaaacc 60 gaggacacgg ccgtgtatta ctgtactagt ctaacactct tcggggagtt agtaacttgg 120 ggccaggga 129 <210> 4917 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4917 Thr Ile Ser Arg Asp Tyr Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Leu Thr 20 25 30 Leu Phe Gly Glu Leu Val Thr Trp Gly Gln Gly 35 40 <210> 4918 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4918 accatctcca gagatgattc aaagaacacg gcgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtactagt ctaacactct tcggggagtt agtaacttgg 120 ggccaggga 129 <210> 4919 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4919 Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Ser Leu Thr 20 25 30 Leu Phe Gly Glu Leu Val Thr Trp Gly Gln Gly 35 40 <210> 4920 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4920 Cys Val Lys Asp Gly Pro Arg Ala Pro Arg Asn Leu Gly Arg Tyr Gly 1 5 10 15 Gly Tyr Phe Asp Asp Trp 20 <210> 4921 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4921 tcgatctatc tgaacatgaa caacctgaga gtcgacgata cggccgtata tttctgtgtg 60 aaagatggcc ctcgcgcgcc ccggaatcta gggagatacg gagggtactt tgacgactgg 120 ggccaggga 129 <210> 4922 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4922 Ser Ile Tyr Leu Asn Met Asn Asn Leu Arg Val Asp Asp Thr Ala Val 1 5 10 15 Tyr Phe Cys Val Lys Asp Gly Pro Arg Ala Pro Arg Asn Leu Gly Arg 20 25 30 Tyr Gly Gly Tyr Phe Asp Asp Trp Gly Gln Gly 35 40 <210> 4923 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4923 acgctctatc tgaacatgaa caacctgaga gtcgacgata cggccgtata tttctgtgtg 60 aaagatggcc ctcgcgcgcc ccggaatcta gggagatacg gagggtactt tgacgactgg 120 ggccaggga 129 <210> 4924 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4924 Thr Leu Tyr Leu Asn Met Asn Asn Leu Arg Val Asp Asp Thr Ala Val 1 5 10 15 Tyr Phe Cys Val Lys Asp Gly Pro Arg Ala Pro Arg Asn Leu Gly Arg 20 25 30 Tyr Gly Gly Tyr Phe Asp Asp Trp Gly Gln Gly 35 40 <210> 4925 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4925 acgctctatc tgaacatcaa caacctgaga gtcgacgata cggccgtata tttctgtgtg 60 aaagatggcc ctcgcgcgcc ccggaatcta gggagatacg gagggtactt tgacgactgg 120 ggccaggga 129 <210> 4926 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4926 Thr Leu Tyr Leu Asn Ile Asn Asn Leu Arg Val Asp Asp Thr Ala Val 1 5 10 15 Tyr Phe Cys Val Lys Asp Gly Pro Arg Ala Pro Arg Asn Leu Gly Arg 20 25 30 Tyr Gly Gly Tyr Phe Asp Asp Trp Gly Gln Gly 35 40 <210> 4927 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4927 Cys Ala His Arg Gly Ala Ala Gly Thr Phe Asn Trp Phe Asp Pro Trp 1 5 10 15 <210> 4928 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4928 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagaggagca gctggtacct tcaactggtt cgacccctgg 120 ggccaggga 129 <210> 4929 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4929 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Gly Ala Ala Gly 20 25 30 Thr Phe Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4930 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4930 caaggacacc tccaaaaacc aggtggtcct acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagaggagca gctggtacct tcaactggtt cgacccctgg 120 ggccaggga 129 <210> 4931 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4931 Gln Gly His Leu Gln Lys Pro Gly Gly Pro Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Gly Ala Ala Gly 20 25 30 Thr Phe Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4932 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4932 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagaggagca gctggtacct tcaactggtt cgacccctgg 120 ggccaggga 129 <210> 4933 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4933 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Gly Ala Ala Gly 20 25 30 Thr Phe Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4934 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4934 Cys Ala Lys Ser Phe Gly Gly Tyr Ile Ser Tyr Gly Asp Tyr Asp Cys 1 5 10 15 Trp <210> 4935 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4935 gtcaattcca aggacaccct gtatctgcaa atgaatagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaatc cttcggaggc tatatttcct acggtgacta cgattgctgg 120 ggccaggga 129 <210> 4936 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4936 Val Asn Ser Lys Asp Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ser Phe Gly Gly Tyr Ile 20 25 30 Ser Tyr Gly Asp Tyr Asp Cys Trp Gly Gln Gly 35 40 <210> 4937 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4937 gtcaattcca agaacaccct gtatctgcaa attaatagcc tgagagccga gtacacggcc 60 gtatattact gtgcgaaatc cttcggaggc tatatttcct acggtgacta cgattgctgg 120 ggccaggga 129 <210> 4938 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4938 Val Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala 1 5 10 15 Glu Tyr Thr Ala Val Tyr Tyr Cys Ala Lys Ser Phe Gly Gly Tyr Ile 20 25 30 Ser Tyr Gly Asp Tyr Asp Cys Trp Gly Gln Gly 35 40 <210> 4939 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4939 gtcaattcca agaacaccct gtatctgcaa atgaatagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaatc cttcggaggc tatatttcct acggtgacta cgattgctgg 120 ggccaggga 129 <210> 4940 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4940 Val Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ser Phe Gly Gly Tyr Ile 20 25 30 Ser Tyr Gly Asp Tyr Asp Cys Trp Gly Gln Gly 35 40 <210> 4941 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4941 Cys Ala Lys Gly Ser Arg Pro Gly Gly Gln Lys Gly Gly Tyr Phe Asp 1 5 10 15 Leu Trp <210> 4942 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4942 aattccaaga acacgctgta tctgcaaatg agcagcctga gagccgagga cccggtcgta 60 tattactgtg cgaaagggtc acgtccaggt ggacaaaagg gggggtactt cgatctctgg 120 ggccgtggc 129 <210> 4943 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4943 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Ser Ser Leu Arg Ala Glu 1 5 10 15 Asp Pro Val Val Tyr Tyr Cys Ala Lys Gly Ser Arg Pro Gly Gly Gln 20 25 30 Lys Gly Gly Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4944 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4944 aattccaaga acacgctgta tctgcaaatg agcagcctga gagccgagga cacggtcgta 60 tattactgtg cgaaagggtc acgtccaggt ggacaaaagg gggggtactt cgatctctgg 120 ggccgtggc 129 <210> 4945 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4945 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Ser Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Val Val Tyr Tyr Cys Ala Lys Gly Ser Arg Pro Gly Gly Gln 20 25 30 Lys Gly Gly Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4946 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4946 aattccaaga acacgctgta tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgaaagggtc acgtccaggt ggacaaaagg gggggtactt cgatctctgg 120 ggccgtggc 129 <210> 4947 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4947 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Ser Arg Pro Gly Gly Gln 20 25 30 Lys Gly Gly Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 4948 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4948 Cys Ala Arg Glu Ser Gly Cys Ser Ser Thr Ser Cys Tyr Phe Ser Trp 1 5 10 15 Phe Asp Pro Trp 20 <210> 4949 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4949 gtcagcacgg catatctgca gatcagcagc ctaaaggctg aggacactgc cgtgtattac 60 tgtgcgagag agagtggttg tagtagtacc agctgctatt ttagctggtt cgacccctgg 120 ggccaggga 129 <210> 4950 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4950 Val Ser Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Glu Ser Gly Cys Ser Ser Thr Ser Cys 20 25 30 Tyr Phe Ser Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4951 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4951 gccagcacgg catatctgca gatcagcagc ctaaaggctg aggacactgc cgtgtattac 60 tgtgcgagag agagtggttg tagtagtacc agctgctatt ttagctggtt cgacccctgg 120 ggccaggga 129 <210> 4952 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4952 Ala Ser Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Glu Ser Gly Cys Ser Ser Thr Ser Cys 20 25 30 Tyr Phe Ser Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4953 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4953 gccagcacgg catatctgca gaccagcagc ctaaaggctg aggacactgc cgtgtattac 60 tgtgcgagag agagtggttg tagtagtacc agctgctatt ttagctggtt cgacccctgg 120 ggccaggga 129 <210> 4954 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4954 Ala Ser Thr Ala Tyr Leu Gln Thr Ser Ser Leu Lys Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Glu Ser Gly Cys Ser Ser Thr Ser Cys 20 25 30 Tyr Phe Ser Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 4955 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4955 Cys Ala Arg Gly Pro Gly Ile Val Val Val Leu Ser Thr Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 4956 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4956 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 cgggggccgg ggatagtagt ggttctttcg acctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4957 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4957 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Pro Gly Ile Val Val Val Leu Ser Thr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4958 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4958 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 cgggggccgg ggatagtagt ggttctttcg acctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4959 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4959 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Pro Gly Ile Val Val Val Leu Ser Thr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4960 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4960 acgatgtatc tgcaaatgaa cagcctgaga gctgaggaca cggccgtata ttactgtgcg 60 cgggggccgg ggatagtagt ggttctttcg acctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4961 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4961 Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Pro Gly Ile Val Val Val Leu Ser Thr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4962 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4962 Cys Ala Lys Arg Glu Asp Tyr Asp Phe Trp Ser Gly Arg Gly Ala Phe 1 5 10 15 Asp Ile Trp <210> 4963 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4963 tccaataact cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aaagggagga ttacgatttt tggagtggcc ggggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 4964 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4964 Ser Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Arg Glu Asp Tyr Asp Phe Trp Ser 20 25 30 Gly Arg Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4965 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4965 tccaagaact cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aaagggagga ttacgatttt tggagtggcc ggggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 4966 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4966 Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Arg Glu Asp Tyr Asp Phe Trp Ser 20 25 30 Gly Arg Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4967 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4967 tccaagaaca cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aaagggagga ttacgatttt tggagtggcc ggggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 4968 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4968 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Arg Glu Asp Tyr Asp Phe Trp Ser 20 25 30 Gly Arg Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4969 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4969 Cys Ala Arg Glu Gly Ala Tyr Gly Asp Tyr Arg Gly Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 4970 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4970 tgcactgcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagagg gggcttacgg tgactatcgt ggctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4971 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4971 Cys Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Gly Ala Tyr Gly Asp Tyr Arg Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4972 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4972 tgcacagcct acttggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagagg gggcttacgg tgactatcgt ggctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4973 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4973 Cys Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Gly Ala Tyr Gly Asp Tyr Arg Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4974 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4974 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagagg gggcttacgg tgactatcgt ggctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 4975 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4975 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Gly Ala Tyr Gly Asp Tyr Arg Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 4976 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4976 Cys Ala Thr Thr Pro Gly Pro Trp Ile Gln Leu Trp Phe Gly Gly Gly 1 5 10 15 Phe Asp Tyr Trp 20 <210> 4977 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4977 atcaccaccg cctacctaca gtggagcagc ctgcaggcct cggacaccgc catttattac 60 tgtgcgacaa cccccgggcc gtggatacaa ctttggtttg gggggggctt tgactactgg 120 ggccaggga 129 <210> 4978 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4978 Ile Thr Thr Ala Tyr Leu Gln Trp Ser Ser Leu Gln Ala Ser Asp Thr 1 5 10 15 Ala Ile Tyr Tyr Cys Ala Thr Thr Pro Gly Pro Trp Ile Gln Leu Trp 20 25 30 Phe Gly Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4979 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4979 atcaccaccg cctacctaca gtggagcagc ctgcaggcct cggacaccgc catgtattac 60 tgtgcgacaa cccccgggcc gtggatacaa ctttggtttg gggggggctt tgactactgg 120 ggccaggga 129 <210> 4980 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4980 Ile Thr Thr Ala Tyr Leu Gln Trp Ser Ser Leu Gln Ala Ser Asp Thr 1 5 10 15 Ala Met Tyr Tyr Cys Ala Thr Thr Pro Gly Pro Trp Ile Gln Leu Trp 20 25 30 Phe Gly Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4981 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4981 atcaccaccg cctacctaca gtggagcagc ctgcaggcct cggacaccgc catgtattac 60 tgtgcgacaa cacccgggcc gtggatacaa ctttggtttg gggggggctt tgactactgg 120 ggccaggga 129 <210> 4982 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4982 Cys Ala Thr Ser Val Leu Pro Tyr His Leu His Phe Asp Tyr Trp 1 5 10 15 <210> 4983 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4983 tccagaaaca attccaagaa cacgctgtat cttcaaatga acagcctgag agccgaggac 60 acggccgtgt attactgtgc gacgtcagtt ctgccttacc atctccactt tgactactgg 120 ggccaggga 129 <210> 4984 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4984 Ser Arg Asn Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Ser Val Leu Pro 20 25 30 Tyr His Leu His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4985 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4985 tccacaaaca attccaacaa cacgctgtat cttcaaatga acagcctgag agccgaggac 60 acggccgtgt attactgtgc gacgtcagtt ctgccttacc atctccactt tgactactgg 120 ggccaggga 129 <210> 4986 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4986 Ser Thr Asn Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Ser Val Leu Pro 20 25 30 Tyr His Leu His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4987 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4987 tacagaaaca attccaagaa cacgctgtat cttaaaatga acagcctgag agccgaggac 60 acggccgtgt attactgtgc gacgtcagtt ctgccttacc atctccactt tgactactgg 120 ggccaggga 129 <210> 4988 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4988 Tyr Arg Asn Asn Ser Lys Asn Thr Leu Tyr Leu Lys Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Ser Val Leu Pro 20 25 30 Tyr His Leu His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 4989 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4989 Cys Ala Arg Val Arg Leu Gly Ile Ala Ala Ala Gln Thr Trp 1 5 10 <210> 4990 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4990 atatcagtag gcatgtccaa gaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggctg tgtattactg tgcgagagtc cgcctcggta tagcggcagc ccaaacctgg 120 ggccaggga 129 <210> 4991 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4991 Ile Ser Val Gly Met Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Arg Leu 20 25 30 Gly Ile Ala Ala Ala Gln Thr Trp Gly Gln Gly 35 40 <210> 4992 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4992 atatcagtag gcacgtccaa gaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggctg tgtattactg tgcgagagtc cgcctcggta tagcggcagc ccaaacctgg 120 ggccaggga 129 <210> 4993 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4993 Ile Ser Val Gly Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Arg Leu 20 25 30 Gly Ile Ala Ala Ala Gln Thr Trp Gly Gln Gly 35 40 <210> 4994 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4994 atatcagtag acacgtccaa gaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggctg tgtattactg tgcgagagtc cgcctcggta tagcagcagc ccaaacctgg 120 ggccaggga 129 <210> 4995 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4995 Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Arg Leu 20 25 30 Gly Ile Ala Ala Ala Gln Thr Trp Gly Gln Gly 35 40 <210> 4996 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4996 Cys Thr Lys Ser Ile Ser Thr Gly Gly Thr Thr Ala Phe Asp Ile Trp 1 5 10 15 <210> 4997 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4997 agaggcaacg ccaagagcac actgtatctg caaatgaaca ctctgagagc cgaggacacg 60 gctatatatt actgtacaaa aagtatatca acaggtggaa ccaccgcttt tgatatctgg 120 ggccaaggg 129 <210> 4998 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4998 Arg Gly Asn Ala Lys Ser Thr Leu Tyr Leu Gln Met Asn Thr Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Ile Tyr Tyr Cys Thr Lys Ser Ile Ser Thr Gly 20 25 30 Gly Thr Thr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 4999 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 4999 agagacaacg ccaagagcac actgtatctg caaatgaaca ctctgagggc cgaggacacg 60 gctatatatt actgtacaaa aagtatatca acaggtggaa ccaccgcttt tgatatctgg 120 ggccaaggg 129 <210> 5000 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5000 Arg Asp Asn Ala Lys Ser Thr Leu Tyr Leu Gln Met Asn Thr Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Ile Tyr Tyr Cys Thr Lys Ser Ile Ser Thr Gly 20 25 30 Gly Thr Thr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5001 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5001 agagacaacg ccaagagcac actgtatctg caaatgaaca ctctgagagc cgaggacacg 60 gctatatatt actgtacaaa aagtatatca acaggtggaa ccaccgcttt tgatatctgg 120 ggccaaggg 129 <210> 5002 <211> 7 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5002 Cys Ala Arg Thr Arg Tyr Trp 1 5 <210> 5003 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5003 atctctgaag accaggctca ccatctccaa ggccacctcc aaaaccaggt ggtccttaca 60 atgaccaaca tggaccctgt ggacacagcc acgtattact gtgcacggac ccggtactgg 120 ggccaggga 129 <210> 5004 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5004 Ile Ser Glu Asp Gln Ala His His Leu Gln Gly His Leu Gln Asn Gln 1 5 10 15 Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr 20 25 30 Tyr Cys Ala Arg Thr Arg Tyr Trp Gly Gln Gly 35 40 <210> 5005 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5005 tctctgaaga ccaggctcac catctccaag gccacctcca aaaaccgggt ggcccttaca 60 atgaccaaca tggaccctgt ggacacagcc acgtattact gtgcacggac ccggtactgg 120 ggccaggga 129 <210> 5006 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5006 Ser Leu Lys Thr Arg Leu Thr Ile Ser Lys Ala Thr Ser Lys Asn Arg 1 5 10 15 Val Ala Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr 20 25 30 Tyr Cys Ala Arg Thr Arg Tyr Trp Gly Gln Gly 35 40 <210> 5007 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5007 tctctgaaga ccaggctcac catctccaag gccacctcca aaaaccaggt ggtccttaca 60 atgaccaaca tggaccctgt ggacacagcc acgtattact gtgcacggac ccggtactgg 120 ggccaggga 129 <210> 5008 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5008 Ser Leu Lys Thr Arg Leu Thr Ile Ser Lys Ala Thr Ser Lys Asn Gln 1 5 10 15 Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr 20 25 30 Tyr Cys Ala Arg Thr Arg Tyr Trp Gly Gln Gly 35 40 <210> 5009 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5009 Cys Val Arg Gly Asp Trp Ala Tyr Trp Tyr Phe Asp Leu Trp 1 5 10 <210> 5010 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5010 ttctccagag acaaccccaa gaacacgctg tatctgcaaa tgaacagtct gagagccgag 60 gacacggctg tgtattattg tgtaagaggg gactgggcct actggtactt cgatctctgg 120 ggccgtggc 129 <210> 5011 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5011 Phe Ser Arg Asp Asn Pro Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Gly Asp Trp 20 25 30 Ala Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5012 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5012 atctccagag acaacgccaa gaacacgctg tatctgcaaa tgaacagtct gagagccgag 60 gacacggctg tgtattattg tgtaagaggg gactgggcct actggtactt cgatctctgg 120 ggccgtggc 129 <210> 5013 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5013 Ile Ser Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Gly Asp Trp 20 25 30 Ala Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5014 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5014 atctccagac acaaccccaa gaacacgctg tatctgcaaa tgaacagtct gagagccgag 60 gacacggctg tgtattattg tgtaagaggg gactgggcct actggtactt cgatctctgg 120 ggccgtggc 129 <210> 5015 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5015 Ile Ser Arg His Asn Pro Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Gly Asp Trp 20 25 30 Ala Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5016 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5016 Cys Ala Thr Asn Pro Gly Ser Tyr Val Tyr Phe Val Tyr Trp 1 5 10 <210> 5017 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5017 atctccaggg acaacgccaa gaactccctg tatctgcaaa tcaacagcct gagagccgag 60 gacacggccc tatattactg tgcgacgaat cctgggagct atgtttattt tgtctactgg 120 ggccaggga 129 <210> 5018 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5018 Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Ile Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Thr Asn Pro Gly 20 25 30 Ser Tyr Val Tyr Phe Val Tyr Trp Gly Gln Gly 35 40 <210> 5019 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5019 atctccaggg acaacgccaa gaactccctg tatctgcaaa tcaacagcct gagagccgac 60 gacacggccg tgtattactg tgcgacgaat cctgggagct acgtctattt tgtctactgg 120 ggccaggga 129 <210> 5020 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5020 Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Ile Asn Ser 1 5 10 15 Leu Arg Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Thr Asn Pro Gly 20 25 30 Ser Tyr Val Tyr Phe Val Tyr Trp Gly Gln Gly 35 40 <210> 5021 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5021 atctccaggc acaacgccaa caactccctg tatctgcaaa tcaacagcct gagagccgag 60 gacacggccc tatattactg tgcgacgaat cctgggagct atgtttattt tgtctactgg 120 ggccaggga 129 <210> 5022 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5022 Ile Ser Arg His Asn Ala Asn Asn Ser Leu Tyr Leu Gln Ile Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Thr Asn Pro Gly 20 25 30 Ser Tyr Val Tyr Phe Val Tyr Trp Gly Gln Gly 35 40 <210> 5023 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5023 Cys Ala Lys Gly Asp Asp Glu Gly Tyr Tyr Gly Met Asp Val Trp 1 5 10 15 <210> 5024 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5024 tccagagaca acgccaagaa ctccctgtat ctgcaaatga acagtctgag agctgaggac 60 acggccttgt attactgtgc aaaaggggac gacgagggat actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5025 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5025 Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Gly Asp Asp Glu 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5026 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5026 tccagagaca accccaacaa ctccctgtat ctgcaaatga acagtctgag agctgaggac 60 acggccttgt attactgtgc aaaaggggac gacgagggat actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5027 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5027 Ser Arg Asp Asn Pro Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Gly Asp Asp Glu 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5028 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5028 tccacagaca accccaagaa ctccctgtat ctgcaaatga acagtctgag agctgaggac 60 acggccttgt attactgtgc aaaaggggac gacgagggat actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5029 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5029 Ser Thr Asp Asn Pro Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Gly Asp Asp Glu 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5030 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5030 Cys Ala Arg Arg Gly Pro Arg Gly Asp Asn Asp Tyr Trp 1 5 10 <210> 5031 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5031 accatgacct gggacaggtc cacgagcact gtttacttgg aggtcaacag cctcaaatct 60 gacgactcgg ccgtatatta ttgtgcgaga aggggccctc ggggtgacaa tgactactgg 120 ggccaggga 129 <210> 5032 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5032 Thr Met Thr Trp Asp Arg Ser Thr Ser Thr Val Tyr Leu Glu Val Asn 1 5 10 15 Ser Leu Lys Ser Asp Asp Ser Ala Val Tyr Tyr Cys Ala Arg Arg Gly 20 25 30 Pro Arg Gly Asp Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 5033 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5033 accatgacca gggacaggtc cacgagcact gtttacttgg aggtgaacag cctcaaatct 60 gacgactcgg ccgtatatta ttgtgcgaga aggggccctc ggggtgacaa tgactactgg 120 ggccaggga 129 <210> 5034 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5034 Thr Met Thr Arg Asp Arg Ser Thr Ser Thr Val Tyr Leu Glu Val Asn 1 5 10 15 Ser Leu Lys Ser Asp Asp Ser Ala Val Tyr Tyr Cys Ala Arg Arg Gly 20 25 30 Pro Arg Gly Asp Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 5035 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5035 accatgacca gggacaggtc cacgagcact gtttacttgg aggtcaacag cctcaaatct 60 gacgactcgg ccgtatatta ttgtgcgaga aggggccctc ggggtgacaa tgactactgg 120 ggccaggga 129 <210> 5036 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5036 Cys Ala Arg Gly Asp Tyr Tyr Tyr Gly Met Asp Val Trp 1 5 10 <210> 5037 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5037 caccatctcc agagaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggggacacgg ctgtgtatta ctgtgcaaga ggtgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5038 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5038 His His Leu Gln Arg Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5039 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5039 accatctcca gagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggggacacgg ctgtgtatta ctgtgcaaga ggtgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5040 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5040 Thr Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5041 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5041 aacatctcca tagaaaatgc caagaactcc ttgtatcttc aaatgaacag cctgagagcc 60 ggggacacgg ctgtgtatta ctgtgcaaga ggtgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5042 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5042 Asn Ile Ser Ile Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5043 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5043 Cys Ala Lys Asp Gly Gly Ser Ser Pro Glu Gly His Asp Ala Phe Asp 1 5 10 15 Ile Trp <210> 5044 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5044 aacgccaaga actccctgta tctgcaaatg aacagtctga gagctgagga cacggccttg 60 tattactgtg caaaagatgg cggcagttca cctgagggtc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5045 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5045 Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Gly Gly Ser Ser Pro Glu 20 25 30 Gly His Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5046 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5046 aacgccaaga actccctgta tctgcaaatg aacagtctga gagctgagga cacggccttg 60 tattactgtg caaaagatgg cggcagctca cctgagggtc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5047 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5047 aacgccaaga actccccgta tctgcaaatg aacagtctga gagctgagga cacggccttg 60 tattactgtg caaaagatgg cggcagctca cctgagggtc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5048 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5048 Asn Ala Lys Asn Ser Pro Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Gly Gly Ser Ser Pro Glu 20 25 30 Gly His Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5049 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5049 Cys Ala Lys Thr Arg Ser Asp Leu Ile Arg Tyr Cys Ser Gly Gly Thr 1 5 10 15 Cys Tyr Phe Phe Asp Ser Trp 20 <210> 5050 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5050 ctgtatctgc aaatgaacag cctgagagcc gaagacgcgg ccgtatatta ctgtgcgaaa 60 acacggagcg acctcatacg atattgtagt ggtggtacct gctacttctt tgactcctgg 120 ggccaggga 129 <210> 5051 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5051 Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Ala Ala Val Tyr 1 5 10 15 Tyr Cys Ala Lys Thr Arg Ser Asp Leu Ile Arg Tyr Cys Ser Gly Gly 20 25 30 Thr Cys Tyr Phe Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 5052 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5052 ctgtatctgc aaatcaacag cctgagagcc gaagacgcgg ccgtatatta ctgtgcgaaa 60 acacggagcg acctcatacg atattgtagt ggtggtacct gctacttctt tgactcctgg 120 ggccaggga 129 <210> 5053 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5053 Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Ala Ala Val Tyr 1 5 10 15 Tyr Cys Ala Lys Thr Arg Ser Asp Leu Ile Arg Tyr Cys Ser Gly Gly 20 25 30 Thr Cys Tyr Phe Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 5054 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5054 atgtatctcc aaatgaacag cctgagagcc gaagacgcgg ccgtatatta ctgtgcgaaa 60 acacggagcg acctcatacg atattgtagt ggtggtacct gctacttctt tgactcctgg 120 ggccaggga 129 <210> 5055 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5055 Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Ala Ala Val Tyr 1 5 10 15 Tyr Cys Ala Lys Thr Arg Ser Asp Leu Ile Arg Tyr Cys Ser Gly Gly 20 25 30 Thr Cys Tyr Phe Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 5056 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5056 Cys Thr Arg Arg Ile Leu Gly Ser Pro Gly Gly Met Asp Val Trp 1 5 10 15 <210> 5057 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5057 tccagagatg attcaaagaa cacggcgtat ctgcaaatga acagcctgaa aaccgaggac 60 acggccgtgt attactgtac tagacgaatc cttgggtccc cgggcggtat ggacgtctgg 120 ggccaaggg 129 <210> 5058 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5058 Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Arg Ile Leu Gly 20 25 30 Ser Pro Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5059 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5059 tccagagatc attcaaacaa cacggcgtat ctgcaaatga acagcctgaa aaccgaggac 60 acggccgtgt attactgtac tagacgaatc cttgggtccc cgggcggtat ggacgtctgg 120 ggccaaggg 129 <210> 5060 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5060 Ser Arg Asp His Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Arg Ile Leu Gly 20 25 30 Ser Pro Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5061 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5061 tccacagatg attcaaacaa cacggcgtat ctgcaaatga acagcctgaa aaccgaggac 60 acggccgtgt attactgtac tagacgaatc cttgggtccc cgggcggtat ggacgtctgg 120 ggccaaggg 129 <210> 5062 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5062 Ser Thr Asp Asp Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Arg Ile Leu Gly 20 25 30 Ser Pro Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5063 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5063 Cys Ala Arg Asp Ala Pro Thr Tyr Tyr Tyr His Ser Ser Gly Tyr Tyr 1 5 10 15 Phe Trp His Phe Asp Leu Trp 20 <210> 5064 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5064 gtctatatgg aactgaccag cctgacactt gacgacacgg ccgtctatta ctgtgcgaga 60 gatgcgccaa catattatta tcatagcagt ggttattatt tctggcactt cgatctgtgg 120 ggccgtggc 129 <210> 5065 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5065 Val Tyr Met Glu Leu Thr Ser Leu Thr Leu Asp Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Asp Ala Pro Thr Tyr Tyr Tyr His Ser Ser Gly Tyr 20 25 30 Tyr Phe Trp His Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5066 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5066 gtctatatgg aactgaccag cctgacactt gacgacacgg ccgtctatta ctgtgcgaga 60 gatgcgccaa catattatta tcatagcagt ggttattatt tctggcactt cgatctctgg 120 ggccgtggc 129 <210> 5067 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5067 gtctatatgg aactgaccag cctgacacct gacgacacgg ccgtctatta ctgtgcgaga 60 gatgcgccaa catattatta tcatagcagt ggttattatt tctggcactt cgatctctgg 120 ggccgtggc 129 <210> 5068 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5068 Val Tyr Met Glu Leu Thr Ser Leu Thr Pro Asp Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Asp Ala Pro Thr Tyr Tyr Tyr His Ser Ser Gly Tyr 20 25 30 Tyr Phe Trp His Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5069 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5069 Cys Gly Val Trp Ser Gly Arg Asn Gly Met Asp Leu Trp 1 5 10 <210> 5070 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5070 accatgacca gggacacctc cataaacaca gcctacatgg agctgagcag cctgaaatct 60 gaggacacgg ccgtgtatta ctgtggcgtc tggagtggcc gaaacggtat ggacctctgg 120 ggccaaggg 129 <210> 5071 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5071 Thr Met Thr Arg Asp Thr Ser Ile Asn Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Lys Ser Glu Asp Thr Ala Val Tyr Tyr Cys Gly Val Trp Ser 20 25 30 Gly Arg Asn Gly Met Asp Leu Trp Gly Gln Gly 35 40 <210> 5072 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5072 accatgacca ggcacacctc cataaacaca gcctacatgg agctgagcag ccttaaatct 60 gaggacacgg ccgtgtatta ctgtggcgtc tggagtggcc gaaacggtat ggacctctgg 120 ggccaaggg 129 <210> 5073 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5073 Thr Met Thr Arg His Thr Ser Ile Asn Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Lys Ser Glu Asp Thr Ala Val Tyr Tyr Cys Gly Val Trp Ser 20 25 30 Gly Arg Asn Gly Met Asp Leu Trp Gly Gln Gly 35 40 <210> 5074 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5074 accatgacca ggcacacctc cataaacaca gcctacatgg agctgagcag cctgaaatct 60 gaggacacgg ccgtgtatta ctgtggcgtc tggagtggcc gaaacggtat ggacctctgg 120 ggccaaggg 129 <210> 5075 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5075 Cys Ala Arg Leu Gly Phe Trp Ser Gly Leu Asp Tyr Trp 1 5 10 <210> 5076 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5076 accatctcaa gagatgattc aaagaactca ctgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtgctaga cttgggtttt ggagtggttt ggactactgg 120 ggccaggga 129 <210> 5077 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5077 Thr Ile Ser Arg Asp Asp Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Gly 20 25 30 Phe Trp Ser Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5078 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5078 accatctcaa gagatgattc aaagaactca ctgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgcgtatta ctgtgctaga cttgggtttt ggagtggttt ggactactgg 120 ggccaggga 129 <210> 5079 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5079 Thr Ile Ser Arg Asp Asp Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Ala Tyr Tyr Cys Ala Arg Leu Gly 20 25 30 Phe Trp Ser Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5080 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5080 accatctcaa gacattattc aaagaactca ctgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtatta ctgtgctaga cttgggtttt ggagtggttt ggactactgg 120 ggccaggga 129 <210> 5081 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5081 Thr Ile Ser Arg His Tyr Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Gly 20 25 30 Phe Trp Ser Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5082 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5082 Cys Thr Arg His Ala Gly Ala Ile Gly Tyr Trp 1 5 10 <210> 5083 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5083 tggttcacca tctccagaga tgattcaaag aacacggcgt atctgcaaat gaacagcctg 60 aaacccgagg acacggccgt gtattactgt actagacatg cgggggcgat aggctactgg 120 ggccaggga 129 <210> 5084 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5084 Trp Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Lys Pro Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg 20 25 30 His Ala Gly Ala Ile Gly Tyr Trp Gly Gln Gly 35 40 <210> 5085 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5085 tggttcacca tctccagaga tgattcaaag aacacggcgt atctgcaaat gaacagcctg 60 aaaaccgagg acacggccgt gtattactgt actagacatg cgggggcgat aggctactgg 120 ggccaggga 129 <210> 5086 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5086 Trp Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg 20 25 30 His Ala Gly Ala Ile Gly Tyr Trp Gly Gln Gly 35 40 <210> 5087 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5087 aggttcacca tctccagaga tgattcaaag aacacggcgt atctgcaaat gaacagcctg 60 aaaaccgagg acacggccgt gtattactgt actagacatg cgggggcgat aggctactgg 120 ggccaggga 129 <210> 5088 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5088 Arg Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg 20 25 30 His Ala Gly Ala Ile Gly Tyr Trp Gly Gln Gly 35 40 <210> 5089 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5089 Cys Ala Arg Gly Asn Leu Tyr Tyr Tyr Gly Ser Gly Ser Tyr Val Pro 1 5 10 15 Trp <210> 5090 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5090 gacaacgcca agaactcgct gtatctgcaa atgagcagcc tgagagccga cgacacggcc 60 gtgtattact gtgcgagagg gaacctgtat tactatggtt cagggagtta tgtcccctgg 120 ggccaggga 129 <210> 5091 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5091 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Ser Ser Leu Arg Ala 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asn Leu Tyr Tyr Tyr 20 25 30 Gly Ser Gly Ser Tyr Val Pro Trp Gly Gln Gly 35 40 <210> 5092 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5092 gacaacgcca agaactcact gtatctgcaa atgaacagcc tgagagccga cgacgcggcc 60 gtgtattact gtgcgagagg gaacctgtat tactatggtt cagggagtta tgtcccctgg 120 ggccaggga 129 <210> 5093 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5093 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Asp Asp Ala Ala Val Tyr Tyr Cys Ala Arg Gly Asn Leu Tyr Tyr Tyr 20 25 30 Gly Ser Gly Ser Tyr Val Pro Trp Gly Gln Gly 35 40 <210> 5094 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5094 gacaacgcca agaactcact gtatctgcaa atgaacagcc tgagagccga cgacacggcc 60 gtgtattact gtgcgagagg gaacctgtat tactatggtt cagggagtta tgtcccctgg 120 ggccaggga 129 <210> 5095 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5095 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asn Leu Tyr Tyr Tyr 20 25 30 Gly Ser Gly Ser Tyr Val Pro Trp Gly Gln Gly 35 40 <210> 5096 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5096 Cys Ala Arg Asp Pro Arg Asn Leu Asp Tyr Tyr Tyr Asp Ser Ser Gln 1 5 10 15 Thr Pro Ala Asp Ala Phe Asp Ile Trp 20 25 <210> 5097 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5097 atggtgctgt ggagcctgag atctgacgac acggccgtgt attactgtgc gagagatccc 60 cgaaacttag actattacta tgatagtagt cagacacccg ccgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5098 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5098 Met Val Leu Trp Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Asp Pro Arg Asn Leu Asp Tyr Tyr Tyr Asp Ser Ser Gln Thr 20 25 30 Pro Ala Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5099 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5099 atggtgctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagatccc 60 cgaaacttag actattacta tgatagtagt cagacacccg ccgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5100 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5100 Met Val Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Asp Pro Arg Asn Leu Asp Tyr Tyr Tyr Asp Ser Ser Gln Thr 20 25 30 Pro Ala Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5101 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5101 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagatccc 60 cgaaacttag actattacta tgatagtagt cagacacccg ccgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5102 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5102 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Asp Pro Arg Asn Leu Asp Tyr Tyr Tyr Asp Ser Ser Gln Thr 20 25 30 Pro Ala Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5103 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5103 Cys Ala Arg Thr Lys Thr Ser Gly Tyr Asp Ser Ser Phe Asp Tyr Trp 1 5 10 15 <210> 5104 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5104 agagatgatt ccaagaacac cttgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccatatatt actgtgcgag aactaaaact agtggctacg attcgtcctt tgactactgg 120 ggccaggga 129 <210> 5105 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5105 Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Thr Lys Thr Ser Gly 20 25 30 Tyr Asp Ser Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5106 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5106 agagataatt ccaagaacac cttgtatttg caaatgaaca gcctgagagc cgaggacacg 60 gccatatatt actgtgcgag aactaaaacc agtggctacg attcgtcctt tgactactgg 120 ggccaggga 129 <210> 5107 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5107 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Thr Lys Thr Ser Gly 20 25 30 Tyr Asp Ser Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5108 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5108 agagataatt ccaagaacac cttgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccatatatt actgtgcgag aactaaaact agtggctacg attcgtcctt tgactactgg 120 ggccaggga 129 <210> 5109 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5109 Cys Ala Arg His Val Gly Tyr Gly Asn Asn Trp Phe Asp Pro Trp 1 5 10 15 <210> 5110 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5110 tcagtagaca cgtccaagaa ccagttctcc ctgaagttga gctctgtgac cgccgcagac 60 acggccatgt attactgtgc gagacatgta ggctatggga acaactggtt cgacccctgg 120 ggccaggga 129 <210> 5111 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5111 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Met Tyr Tyr Cys Ala Arg His Val Gly Tyr 20 25 30 Gly Asn Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5112 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5112 tcagtagaca cgtccgagaa ccacttctcc ctgagtctga cctctgtgac cgccgcagac 60 acggccgtgt attactgtgc gagacatgtt ggctacggga acaactggtt cgacccctgg 120 ggccaggga 129 <210> 5113 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5113 Ser Val Asp Thr Ser Glu Asn His Phe Ser Leu Ser Leu Thr Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg His Val Gly Tyr 20 25 30 Gly Asn Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5114 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5114 tcagtagaca cgtccaagaa ccacttctcc ctgagtctga gctctgtgac cgccgcagac 60 acggccgtgt attactgtgc gagacatgta ggctacggga acaactggtt cgacccctgg 120 ggccaggga 129 <210> 5115 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5115 Ser Val Asp Thr Ser Lys Asn His Phe Ser Leu Ser Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg His Val Gly Tyr 20 25 30 Gly Asn Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5116 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5116 Cys Ala Lys Gly Glu Phe Arg Asn Tyr Asp Phe Trp Ser Gly Tyr Leu 1 5 10 15 Asp Gly Met Asp Val Trp 20 <210> 5117 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5117 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaaggagagt tccggaatta cgatttttgg agtggttatt tggacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5118 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5118 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Gly Glu Phe Arg Asn Tyr Asp Phe Trp Ser Gly 20 25 30 Tyr Leu Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5119 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5119 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaaggagagt tccggaatta cgatttttgg agtggttatt tggacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5120 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5120 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Gly Glu Phe Arg Asn Tyr Asp Phe Trp Ser Gly 20 25 30 Tyr Leu Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5121 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5121 acgctgtatc tccaaatcaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaaggagagt tccggaatta cgatttttgg agtggttatt tggacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5122 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5122 Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Gly Glu Phe Arg Asn Tyr Asp Phe Trp Ser Gly 20 25 30 Tyr Leu Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5123 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5123 Cys Ala His Gly Leu Gly Gly Trp Asp Gly Gln Tyr Phe Asp His Trp 1 5 10 15 <210> 5124 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5124 aaggacacgt ccaataacca ggtggtcctt agaatgacca acatggaccc tgcagacaca 60 gccacatatt actgtgcaca cggtcttgga ggctgggatg ggcagtattt tgaccactgg 120 gggcaggga 129 <210> 5125 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5125 Lys Asp Thr Ser Asn Asn Gln Val Val Leu Arg Met Thr Asn Met Asp 1 5 10 15 Pro Ala Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Leu Gly Gly Trp 20 25 30 Asp Gly Gln Tyr Phe Asp His Trp Gly Gln Gly 35 40 <210> 5126 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5126 aaggacacgt ccaaaaacca ggtggtgctt agaatgacca acatgaaccc tgcggacaca 60 gccacatatt actgtgcaca cggtcttgga ggctgggatg ggcagtattt tgaccactgg 120 gggcaggga 129 <210> 5127 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5127 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Arg Met Thr Asn Met Asn 1 5 10 15 Pro Ala Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Leu Gly Gly Trp 20 25 30 Asp Gly Gln Tyr Phe Asp His Trp Gly Gln Gly 35 40 <210> 5128 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5128 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cggtcttgga ggctgggatg ggcagtattt tgaccactgg 120 gggcaggga 129 <210> 5129 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5129 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Leu Gly Gly Trp 20 25 30 Asp Gly Gln Tyr Phe Asp His Trp Gly Gln Gly 35 40 <210> 5130 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5130 Cys Ala Thr Ser Gly Ser Tyr Tyr Cys Phe Gly Tyr Trp 1 5 10 <210> 5131 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5131 accatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgacc agtgggagct actattgttt cggctactgg 120 ggccaggga 129 <210> 5132 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5132 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Ser Gly 20 25 30 Ser Tyr Tyr Cys Phe Gly Tyr Trp Gly Gln Gly 35 40 <210> 5133 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5133 accatctcca tacataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgacc agtgggagct actattgttt cggctactgg 120 ggccaggga 129 <210> 5134 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5134 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Ser Gly 20 25 30 Ser Tyr Tyr Cys Phe Gly Tyr Trp Gly Gln Gly 35 40 <210> 5135 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5135 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgacc agtgggagct actattgttt cggctactgg 120 ggccaggga 129 <210> 5136 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5136 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Ser Gly 20 25 30 Ser Tyr Tyr Cys Phe Gly Tyr Trp Gly Gln Gly 35 40 <210> 5137 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5137 Cys Ala Lys Gly Tyr Gly Ser Gly Ser Tyr Asn Pro Gly Asn Phe Asp 1 5 10 15 Tyr Trp <210> 5138 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5138 tattccaaga acacgctgtt tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattattgtg cgaaaggtta tggttcaggg agttataatc ccggaaactt tgactactgg 120 ggccaggga 129 <210> 5139 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5139 Tyr Ser Lys Asn Thr Leu Phe Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Tyr Gly Ser Gly Ser Tyr 20 25 30 Asn Pro Gly Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5140 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5140 acttccaaga acacgctgtt tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattattgtg cgaaaggtta tggttcaggg agttataatc ccggaaactt tgactactgg 120 ggccaggga 129 <210> 5141 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5141 Thr Ser Lys Asn Thr Leu Phe Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Tyr Gly Ser Gly Ser Tyr 20 25 30 Asn Pro Gly Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5142 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5142 aattccaaga acacgctgtt tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattattgtg cgaaaggtta tggttcaggg agttataatc ccggaaactt tgactactgg 120 ggccaggga 129 <210> 5143 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5143 Asn Ser Lys Asn Thr Leu Phe Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Tyr Gly Ser Gly Ser Tyr 20 25 30 Asn Pro Gly Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5144 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5144 Cys Ala Arg Glu Gly Ala Asp Tyr Asp Ser Val Ser Gln Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 5145 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5145 acagtctaca tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agagaggggg ccgactatga tagtgtcagc caatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5146 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5146 Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Glu Gly Ala Asp Tyr Asp Ser Val Ser Gln Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5147 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5147 acagtctaca tggagctgag cagcctgaga tctgaggaca cggccgtgta ctactgtgcg 60 agagaggggg ccgactatga tagtgtcagc caatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5148 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5148 aaagtctaca tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agagaggggg ccgactatga tagtgtcagc caatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5149 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5149 Lys Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Glu Gly Ala Asp Tyr Asp Ser Val Ser Gln Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5150 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5150 Cys Val Arg Gly Gly Gly Gly Ser Gly Ser Ser Pro Pro Phe Glu Tyr 1 5 10 15 Trp <210> 5151 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5151 gacacgtcca cgagcacatt ctacatggag ctgagcagcc tgaggtctga ggacacggcc 60 gtgtattatt gtgtgagagg gggcggcggt tcagggagct ccccaccttt tgaatactgg 120 ggccaggga 129 <210> 5152 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5152 Asp Thr Ser Thr Ser Thr Phe Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Gly Gly Gly Gly Ser Gly 20 25 30 Ser Ser Pro Pro Phe Glu Tyr Trp Gly Gln Gly 35 40 <210> 5153 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5153 gacacgtcca cgagcacatt ctacatggag ctgagcagcc tgagggctga ggacacggcc 60 gtgtattatt gtgtgagagg gggcggcggt tcagggagct ccccaccttt tgaatactgg 120 ggccaggga 129 <210> 5154 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5154 Asp Thr Ser Thr Ser Thr Phe Tyr Met Glu Leu Ser Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Gly Gly Gly Gly Ser Gly 20 25 30 Ser Ser Pro Pro Phe Glu Tyr Trp Gly Gln Gly 35 40 <210> 5155 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5155 gacacgccca cgagcacatt ctacatggag ctgagcagcc tgaggtctga ggacacggcc 60 gtgtattatt gtgtgagagg gggcggcggt tcagggagct ccccaccttt tgaatactgg 120 ggccaggga 129 <210> 5156 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5156 Asp Thr Pro Thr Ser Thr Phe Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Gly Gly Gly Gly Ser Gly 20 25 30 Ser Ser Pro Pro Phe Glu Tyr Trp Gly Gln Gly 35 40 <210> 5157 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5157 Cys Ala Arg Ala Gly Trp Arg Leu Gln Val Pro Phe Cys Asp Tyr Trp 1 5 10 15 <210> 5158 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5158 tgggacaacg ccaagaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgcgag ggctggttgg agactgcaag tccccttttg tgactactgg 120 ggccaggga 129 <210> 5159 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5159 Trp Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Gly Trp Arg Leu 20 25 30 Gln Val Pro Phe Cys Asp Tyr Trp Gly Gln Gly 35 40 <210> 5160 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5160 agggacaacg ccaagaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgcgag ggctggttgg agactgcaag tccccttttg tgactactgg 120 ggccaggga 129 <210> 5161 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5161 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Gly Trp Arg Leu 20 25 30 Gln Val Pro Phe Cys Asp Tyr Trp Gly Gln Gly 35 40 <210> 5162 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5162 Cys Ala Lys Gly Pro Trp Asp Ser Ser Gly Trp Tyr Tyr Phe Asp Tyr 1 5 10 15 Trp <210> 5163 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5163 tataattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaagg tccttgggat agcagtggct ggtactactt tgactactgg 120 ggccaggga 129 <210> 5164 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5164 Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Pro Trp Asp Ser Ser 20 25 30 Gly Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5165 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5165 gataattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaagg tccttgggat agcagtggct ggtactactt tgactactgg 120 ggccaggga 129 <210> 5166 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5166 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Pro Trp Asp Ser Ser 20 25 30 Gly Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5167 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5167 Cys Ala Arg Asp Arg Ser Ile Thr Ile Phe Gly Val Ala Pro Leu Asp 1 5 10 15 Gly Tyr Gly Met Asp Val Trp 20 <210> 5168 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5168 ctttatattc aaatgaacag cctgagagcc gaggacacgg ccgtgtatta ctgtgcgaga 60 gatcggagta ttacgatttt tggagtggcc cccctcgacg ggtacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5169 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5169 Leu Tyr Ile Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Asp Arg Ser Ile Thr Ile Phe Gly Val Ala Pro Leu 20 25 30 Asp Gly Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5170 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5170 ctgtatcttc aaatgaacag cctgagagcc gaggacacgg ccgtgtatta ctgtgcgaga 60 gatcggagta ttacgatttt tggagtggcc cccctcgacg ggtacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5171 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5171 Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Asp Arg Ser Ile Thr Ile Phe Gly Val Ala Pro Leu 20 25 30 Asp Gly Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5172 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5172 Cys Ala Thr Leu Leu Leu Arg Gly Lys Leu Asp Val Trp 1 5 10 <210> 5173 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5173 agcatcaacc cagacacatc caagaacctg ttctccctgc agctgaactc tgtgactccc 60 gaggacacgg ctgtttatta ctgtgcaaca ttattgcttc gggggaagtt ggacgtctgg 120 ggccaaggg 129 <210> 5174 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5174 Ser Ile Asn Pro Asp Thr Ser Lys Asn Leu Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Leu Leu 20 25 30 Leu Arg Gly Lys Leu Asp Val Trp Gly Gln Gly 35 40 <210> 5175 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5175 accatcaacc cagacacatc caagaaccag ttctccctgc agttgaactc tgtgactccc 60 gaggatacgg gtgtttatta ctgtgcaaca ttattgcttc gggggaagtt ggacgtctgg 120 ggccaaggg 129 <210> 5176 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5176 Thr Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Glu Asp Thr Gly Val Tyr Tyr Cys Ala Thr Leu Leu 20 25 30 Leu Arg Gly Lys Leu Asp Val Trp Gly Gln Gly 35 40 <210> 5177 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5177 Cys Ala Arg Val Trp Ser Ser Ser Ser Val Phe Asp Tyr Trp 1 5 10 <210> 5178 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5178 ttgaccacac acacatccac gagcacagcc tacatggagc tgaggagcct gagatctgac 60 gacacggccg tgtattactg tgcgagagtt tggagcagct cgtccgtctt tgactactgg 120 ggccaggga 129 <210> 5179 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5179 Leu Thr Thr His Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser 1 5 10 15 Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Trp Ser 20 25 30 Ser Ser Ser Val Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5180 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5180 atgaccacag acacatccac gagcacagcc tacatggagc tgaggagcct gagatctgac 60 gacacggccg tgtattactg tgcgagagtt tggagcagct cgtccgtctt tgactactgg 120 ggccaggga 129 <210> 5181 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5181 Met Thr Thr Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser 1 5 10 15 Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Trp Ser 20 25 30 Ser Ser Ser Val Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5182 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5182 Cys Ala Arg Ser Asp Tyr Tyr Asp Ser Ser Gly Tyr Arg Asn Trp 1 5 10 15 <210> 5183 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5183 ctccaaggac acctccaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acgatcggat tactatgata gtagtggtta tcgtaactgg 120 ggccaggga 129 <210> 5184 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5184 Leu Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ser Asp Tyr Tyr 20 25 30 Asp Ser Ser Gly Tyr Arg Asn Trp Gly Gln Gly 35 40 <210> 5185 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5185 tccaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acgatcggat tactatgata gtagtggtta tcgtaactgg 120 ggccaggga 129 <210> 5186 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5186 Ser Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ser Asp Tyr Tyr 20 25 30 Asp Ser Ser Gly Tyr Arg Asn Trp Gly Gln Gly 35 40 <210> 5187 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5187 Cys Thr Thr Asp Arg Pro Ser Tyr Tyr Asp Phe Trp Arg Pro Asp Phe 1 5 10 15 Asp Tyr Trp <210> 5188 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5188 tcaaaaaaca cgctgtatct gcaaatgaac agcctgaaaa ccgaggacac agccgtgtat 60 tactgtacca cagatcggcc cagttattac gatttttgga ggccggactt tgactactgg 120 ggccaggga 129 <210> 5189 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5189 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Thr Asp Arg Pro Ser Tyr Tyr Asp Phe 20 25 30 Trp Arg Pro Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5190 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5190 ttcaaaaaca cgctgtatct gcaaatgaac agcctgaaaa ccgaggacac agccgtgtat 60 tactgtacca cagatcggcc cagttattac gatttttgga ggccggactt tgactactgg 120 ggccaggga 129 <210> 5191 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5191 Phe Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Thr Asp Arg Pro Ser Tyr Tyr Asp Phe 20 25 30 Trp Arg Pro Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5192 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5192 Cys Thr Thr Pro Phe Phe Arg Leu Pro Gln Ala Trp 1 5 10 <210> 5193 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5193 ttcaccatct caagagatga ttcaaaaaac atggtgtatc tgcaaatgaa cagcctgaaa 60 accgaggaca cagccgtgta ttattgtacc acccctttct tccggctgcc ccaggcctgg 120 ggcctggga 129 <210> 5194 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5194 Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Met Val Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Pro 20 25 30 Phe Phe Arg Leu Pro Gln Ala Trp Gly Leu Gly 35 40 <210> 5195 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5195 ttcaccatct caagagatga ttcaaaaaac atggtgtatc tgcaaatgaa caacctgaaa 60 accgaggaca cagccgtgta ttattgtacc acccctttct tccggctgcc ccaggcctgg 120 ggcctggga 129 <210> 5196 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5196 Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Met Val Tyr Leu Gln Met 1 5 10 15 Asn Asn Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Pro 20 25 30 Phe Phe Arg Leu Pro Gln Ala Trp Gly Leu Gly 35 40 <210> 5197 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5197 Cys Thr Ser Pro Tyr Lys Tyr Gly Ser Gly Ser Tyr Tyr Asp Tyr Tyr 1 5 10 15 Tyr Tyr Gly Met Asp Val Trp 20 <210> 5198 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5198 gcgtatctgc aaatgaacag cctgaaaacc gaggacacgg ccgtgtatta ctgtactagc 60 ccttacaaat atggttcggg gagttattac gactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5199 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5199 Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Thr Ser Pro Tyr Lys Tyr Gly Ser Gly Ser Tyr Tyr Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5200 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5200 gagtatctgc aaatcaacag cctgaaaacc gaggacacgg ccgtgtatta ctgtactagc 60 ccttacaaat atggttcggg gagttattac gactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5201 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5201 Glu Tyr Leu Gln Ile Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Thr Ser Pro Tyr Lys Tyr Gly Ser Gly Ser Tyr Tyr Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5202 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5202 Cys Thr Thr Pro Gly Asp Gly Pro Asn Asp Tyr Trp 1 5 10 <210> 5203 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5203 ttcaccatct caagagatga ttcaaaaaac gcgctgtatc tgcaaatgaa cagcctgaaa 60 accgaggaca cagccgtgta ttactgtacc acacctggtg acggacccaa tgactactgg 120 ggccaggga 129 <210> 5204 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5204 Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Ala Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Pro 20 25 30 Gly Asp Gly Pro Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 5205 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5205 ttcaccatct caagagatga ttcaaaaaac acgctgtatc tgcaaatgaa cagcctgaaa 60 accgaggaca cagccgtgta ttactgtacc acacctggtg acggacccaa tgactactgg 120 ggccaggga 129 <210> 5206 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5206 Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Pro 20 25 30 Gly Asp Gly Pro Asn Asp Tyr Trp Gly Gln Gly 35 40 <210> 5207 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5207 Cys Ala Lys Asp Arg Ser Gly Trp Asn Gly Gly Phe His Phe Trp 1 5 10 15 <210> 5208 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5208 ctccagagat acttccaaaa tacactttat ctacaaatga acagcctgag ggccgaggac 60 acggccgtat attactgtgc gaaagatcgc agtggctgga acgggggatt ccacttctgg 120 ggccagggc 129 <210> 5209 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5209 Leu Gln Arg Tyr Phe Gln Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Ser Gly 20 25 30 Trp Asn Gly Gly Phe His Phe Trp Gly Gln Gly 35 40 <210> 5210 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5210 tccagagata cttccaaaaa tacactttat ctacaaatga acagcctgag ggccgaggac 60 acggccgtat attactgtgc gaaagatcgc agtggctgga acgggggatt ccacttctgg 120 ggccagggc 129 <210> 5211 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5211 Ser Arg Asp Thr Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Ser Gly 20 25 30 Trp Asn Gly Gly Phe His Phe Trp Gly Gln Gly 35 40 <210> 5212 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5212 Cys Ala Lys Ser Thr Asp Phe Trp Ser Gly Gly Phe Asp Ser Trp 1 5 10 15 <210> 5213 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5213 tccagagaca attccaagga cacgctgtat ctgcagatgg acagcctgag agtcgaggac 60 acggccgtat attactgtgc aaagtctacc gatttttgga gtggtggttt tgactcctgg 120 ggccaggga 129 <210> 5214 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5214 Ser Arg Asp Asn Ser Lys Asp Thr Leu Tyr Leu Gln Met Asp Ser Leu 1 5 10 15 Arg Val Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ser Thr Asp Phe 20 25 30 Trp Ser Gly Gly Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 5215 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5215 tccagacaca attccacgga cacgctgtat ctgcagatgg acagcctgag agtcgaggac 60 acggccgtat attactgtgc aaagtctacc gatttttgga gtggtggttt tgactcctgg 120 ggccaggga 129 <210> 5216 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5216 Ser Arg His Asn Ser Thr Asp Thr Leu Tyr Leu Gln Met Asp Ser Leu 1 5 10 15 Arg Val Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ser Thr Asp Phe 20 25 30 Trp Ser Gly Gly Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 5217 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5217 Cys Ala Arg Asp Arg Asp Phe Arg Asp Leu Asp Tyr Trp 1 5 10 <210> 5218 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5218 atcatcaacc cagacacatc caggaaccag ttctccctgc agctgaactc tgtgactccc 60 gcggacacgg ctgtgtatta ctgtgcaaga gatagggatt tcagggatct tgactactgg 120 ggccaggga 129 <210> 5219 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5219 Ile Ile Asn Pro Asp Thr Ser Arg Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg 20 25 30 Asp Phe Arg Asp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5220 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5220 atcatcaacc cagacacatc caagaaccag ttctccctgc agctgaactc tgtgactccc 60 gcggacacgg ctgtgtatta ctgtgcaaga gatagggatt tcagggatct tgactactgg 120 ggccaggga 129 <210> 5221 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5221 Ile Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg 20 25 30 Asp Phe Arg Asp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5222 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5222 Cys Ala Arg Pro Ala Ser Ser Ser Gly Trp Tyr Gly Gly Leu Asp Tyr 1 5 10 15 Trp <210> 5223 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5223 gacaagtcta tcaccaccgc ctacctgcag tggagcagcc tgaaggcctc ggacaccgcc 60 atgtattact gtgcgagacc agcatctagc agtggctggt acggaggatt ggactactgg 120 ggccaggga 129 <210> 5224 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5224 Asp Lys Ser Ile Thr Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala 1 5 10 15 Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Pro Ala Ser Ser Ser Gly 20 25 30 Trp Tyr Gly Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5225 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5225 gacaagtcca tcagcaccgc ctacctgcag tggagcagcc tgaaggcctc ggacaccgcc 60 atgtatttct gtgcgagacc agcatctagc agtggctggt acggaggatt ggactactgg 120 ggccaggga 129 <210> 5226 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5226 Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala 1 5 10 15 Ser Asp Thr Ala Met Tyr Phe Cys Ala Arg Pro Ala Ser Ser Ser Gly 20 25 30 Trp Tyr Gly Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5227 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5227 Cys Ala Lys Asp Met Gln Asn Phe Asp Tyr Trp 1 5 10 <210> 5228 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5228 cggttcacca tctccagaga caattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaagaca tgcaaaactt tgactactgg 120 ggccaggga 129 <210> 5229 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5229 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Asp Met Gln Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5230 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5230 cggttcacca tctccagaca caattccaag aacacgctgt atctgcaaat caacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaagaca tgcaaaactt tgactactgg 120 ggccaggga 129 <210> 5231 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5231 Arg Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Asp Met Gln Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5232 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5232 Cys Ala Lys Ala Lys Glu Gly Trp Leu Phe Arg Gly Tyr Phe Asp Tyr 1 5 10 15 Trp <210> 5233 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5233 gacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaagc gaaggagggg tggttatttc gggggtactt tgactactgg 120 ggccaggga 129 <210> 5234 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5234 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Lys Glu Gly Trp Leu 20 25 30 Phe Arg Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5235 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5235 gacaattcca agaacacgct gtatctacaa ataaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaagc gaaggagggg tggttatttc gggggtactt tgactactgg 120 ggccaggga 129 <210> 5236 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5236 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Lys Glu Gly Trp Leu 20 25 30 Phe Arg Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5237 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5237 Cys Ala Arg Met Val Ala Pro Ile Tyr Tyr Phe Tyr Gly Met Asp Val 1 5 10 15 Trp <210> 5238 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5238 gacacctcca gaaaccaggt ggtccttaca atgaccaacg tggaccctgt ggacacagcc 60 acgtattact gtgcacggat ggtggccccc atctactact tctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5239 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5239 Asp Thr Ser Arg Asn Gln Val Val Leu Thr Met Thr Asn Val Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Met Val Ala Pro Ile Tyr 20 25 30 Tyr Phe Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5240 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5240 gacaccccca gaaaccaggt ggtccttaca atgaccaacg tggaccctgt ggacacagcc 60 acgtgttact gtgcacggat ggtggccccc atctactact tctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5241 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5241 Asp Thr Pro Arg Asn Gln Val Val Leu Thr Met Thr Asn Val Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Cys Tyr Cys Ala Arg Met Val Ala Pro Ile Tyr 20 25 30 Tyr Phe Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5242 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5242 Cys Ala Arg Val Arg Asp Gly Ala Leu Leu Asp Tyr Trp 1 5 10 <210> 5243 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5243 acgattaccg cggacaaatc cacgagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga gtgagggacg gtgccctact tgactactgg 120 ggccgggga 129 <210> 5244 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5244 Thr Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Arg 20 25 30 Asp Gly Ala Leu Leu Asp Tyr Trp Gly Arg Gly 35 40 <210> 5245 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5245 acgattaccg cggacaaatc cacgagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga gtgagggacg gtgccctact tgactactgg 120 ggccaggga 129 <210> 5246 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5246 Thr Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Arg 20 25 30 Asp Gly Ala Leu Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5247 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5247 Cys Ala Arg Glu Thr Val Asp Thr Ala Met Val Tyr Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 5248 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5248 tgcacagcct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagaga ccgtggatac agctatggtc tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5249 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5249 Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Thr Val Asp Thr Ala Met Val Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5250 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5250 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagaga ccgtggatac agctatggtc tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5251 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5251 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Thr Val Asp Thr Ala Met Val Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5252 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5252 Cys Ala Lys Ala Gly Gly Asn Pro Thr Asp Ala Phe Asp Ile Trp 1 5 10 15 <210> 5253 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5253 tccagatata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaagccggt ggtaacccta cggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5254 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5254 Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Gly Gly Asn 20 25 30 Pro Thr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5255 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5255 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaagccggt ggtaacccta cggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5256 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5256 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Gly Gly Asn 20 25 30 Pro Thr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5257 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5257 Cys Ala Arg Gly Asp Ser Gly Asp Arg Asp Thr Ala Met Val Lys Gly 1 5 10 15 Tyr Phe Asp Tyr Trp 20 <210> 5258 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5258 tgcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagggg attcgggaga ccgggataca gctatggtta aggggtactt tgactactgg 120 ggccaggga 129 <210> 5259 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5259 Cys Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Asp Ser Gly Asp Arg Asp Thr Ala Met 20 25 30 Val Lys Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5260 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5260 agcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagggg attcgggaga ccgggataca gctatggtta aggggtactt tgactactgg 120 ggccaggga 129 <210> 5261 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5261 Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Asp Ser Gly Asp Arg Asp Thr Ala Met 20 25 30 Val Lys Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5262 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5262 Cys Ala Ser Ser Cys Gly Gly Tyr Ala His Ala Cys Phe Asp Tyr Trp 1 5 10 15 <210> 5263 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5263 tgggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag ctcatgcggt ggctacgccc atgcctgttt tgactactgg 120 ggccaggga 129 <210> 5264 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5264 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Ser Cys Gly Gly Tyr 20 25 30 Ala His Ala Cys Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5265 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5265 agggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag ctcatgcggt ggctacgccc atgcctgttt tgactactgg 120 ggccaggga 129 <210> 5266 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5266 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Ser Cys Gly Gly Tyr 20 25 30 Ala His Ala Cys Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5267 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5267 Cys Ala Ser Arg Gly Ile Thr Met Val Arg Gly Ala Ala Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 5268 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5268 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagtagag gtattactat ggttcggggc gcagcctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5269 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5269 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Ser Arg Gly Ile Thr Met Val Arg Gly Ala Ala 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5270 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5270 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagtagag gtattactat ggttcggggc gcagcctact actacggtat ggacgtctgg 120 agccaaggg 129 <210> 5271 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5271 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Ser Arg Gly Ile Thr Met Val Arg Gly Ala Ala 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Ser Gln Gly 35 40 <210> 5272 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5272 Cys Glu Ser Gly Leu Ala Gly Leu Leu Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 5273 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5273 ctcaagcaac accctttaag tgcagtctgc cttacaatga ccaatctgaa agccaaggac 60 aaggtcatgt attactgtga gtctgggctg gctgggctcc tttactactt tgactactgg 120 ggccaggga 129 <210> 5274 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5274 Leu Lys Gln His Pro Leu Ser Ala Val Cys Leu Thr Met Thr Asn Leu 1 5 10 15 Lys Ala Lys Asp Lys Val Met Tyr Tyr Cys Glu Ser Gly Leu Ala Gly 20 25 30 Leu Leu Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5275 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5275 tcaagcaaca cccttttaag tgcagtctgc cttacaatga ccaatctgaa agccaaggac 60 aaggtcatgt attactgtga gtctgggctg gctgggctcc tttactactt tgactactgg 120 ggccaggga 129 <210> 5276 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5276 Ser Ser Asn Thr Leu Leu Ser Ala Val Cys Leu Thr Met Thr Asn Leu 1 5 10 15 Lys Ala Lys Asp Lys Val Met Tyr Tyr Cys Glu Ser Gly Leu Ala Gly 20 25 30 Leu Leu Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5277 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5277 Cys Ala Lys Leu Val Gln Arg Ala Gly Ser Asp Tyr Trp 1 5 10 <210> 5278 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5278 accatttcca gagacaacac caagaactcc ctctttctgc aaatgaacag tctgagacct 60 gaggacacgg ccttgtatta ctgtgcaaaa ctggtccaac gagctggttc ggactactgg 120 ggccaggga 129 <210> 5279 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5279 Thr Ile Ser Arg Asp Asn Thr Lys Asn Ser Leu Phe Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Pro Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Leu Val 20 25 30 Gln Arg Ala Gly Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 5280 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5280 aacatttcca gagacaacac caagaactcc ctctttctgc aaatgaacag tctgagacct 60 gaggacacgg ccttgtatta ctgtgcaaaa ctggtccaac gagctggttc ggactactgg 120 ggccaggga 129 <210> 5281 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5281 Asn Ile Ser Arg Asp Asn Thr Lys Asn Ser Leu Phe Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Pro Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Leu Val 20 25 30 Gln Arg Ala Gly Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 5282 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5282 Cys Ala Lys Asp Arg Ala Ala Gly Ile Tyr Gly Met Asp Val Trp 1 5 10 15 <210> 5283 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5283 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaagatcgg gcagctggta tttacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5284 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5284 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Ala Ala 20 25 30 Gly Ile Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5285 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5285 tacagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgatgac 60 acggccgtat attactgtgc gaaagatcgg gcagctggta tttacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5286 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5286 Tyr Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Ala Ala 20 25 30 Gly Ile Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5287 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5287 Cys Thr Thr Arg Leu Ser Asn Gly Ala Ala Ala Gly Ser Pro Asp Ala 1 5 10 15 Phe Asp Ile Trp 20 <210> 5288 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5288 aaaaacacgc tgtatctgca aatgaacagc ctgaaaaccg aggacacagc cgtgtattac 60 tgtaccacaa gactatccaa tggggcagca gctggtagcc ctgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5289 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5289 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Thr Thr Arg Leu Ser Asn Gly Ala Ala Ala Gly 20 25 30 Ser Pro Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5290 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5290 aaaaacacgc tgtatccgca aatgaacagc ctgaaaaccg aggacacagc cgtgtattac 60 tgtaccacaa gactatccaa tggggcagca gctggtagcc ctgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5291 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5291 Lys Asn Thr Leu Tyr Pro Gln Met Asn Ser Leu Lys Thr Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Thr Thr Arg Leu Ser Asn Gly Ala Ala Ala Gly 20 25 30 Ser Pro Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5292 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5292 Cys Ala Ala Gln Arg Arg Asp Gly Tyr Ile Ser Tyr Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 5293 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5293 tgcacagcct acttggagct gagcagcctg agatccgagg acacggccgt gtattactgt 60 gcggcacaac gtagagatgg ctacatatca tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5294 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5294 Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Ala Gln Arg Arg Asp Gly Tyr Ile Ser Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5295 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5295 agcacagcct acatggagct gagcagcctg agatccgagg acacggccgt gtattactgt 60 gcggcacaac gtagagatgg ctacatatca tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5296 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5296 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Ala Gln Arg Arg Asp Gly Tyr Ile Ser Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5297 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5297 Cys Ala Lys Gly Ala Ser Leu Gly Phe Gly Glu Leu Phe Asp Tyr Trp 1 5 10 15 <210> 5298 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5298 ttagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa aggagcctct ttggggttcg gggagttatt tgactactgg 120 ggccaggga 129 <210> 5299 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5299 Leu Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Ala Ser Leu Gly 20 25 30 Phe Gly Glu Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5300 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5300 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa aggagcctct ttggggttcg gggagttatt tgactactgg 120 ggccaggga 129 <210> 5301 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5301 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Ala Ser Leu Gly 20 25 30 Phe Gly Glu Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5302 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5302 Cys Ala Arg Ser Arg Pro Ser Val Gly Gly Ala Phe Asp Ile Trp 1 5 10 15 <210> 5303 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5303 gaccaggaca cgtccatcag cacagcctac atggagctga gcagcctcag atctgacgac 60 acggtcgtgt tttactgtgc gagatcgcgg cctagtgtgg gcggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 5304 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5304 Asp Gln Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Asp Asp Thr Val Val Phe Tyr Cys Ala Arg Ser Arg Pro Ser 20 25 30 Val Gly Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5305 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5305 accagggaca cgtccatcag cacagcctac atggagctga gcagcctcag atctgacgac 60 acggtcgtgt tttactgtgc gagatcgcgg cctagtgtgg gcggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 5306 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5306 Thr Arg Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Asp Asp Thr Val Val Phe Tyr Cys Ala Arg Ser Arg Pro Ser 20 25 30 Val Gly Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5307 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5307 Cys Ala Arg Leu Phe Tyr Tyr Asp Ser Ser Ala Tyr Tyr Leu Gly Tyr 1 5 10 15 Tyr Phe Asp Tyr Trp 20 <210> 5308 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5308 tactccatgt atctgcaaat gaacaccctg agagacgagg acacggctgt gtattactgt 60 gcgagactgt tttactatga tagtagtgct tattacttgg gttactactt tgactactgg 120 ggccaggga 129 <210> 5309 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5309 Tyr Ser Met Tyr Leu Gln Met Asn Thr Leu Arg Asp Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Leu Phe Tyr Tyr Asp Ser Ser Ala Tyr Tyr 20 25 30 Leu Gly Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5310 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5310 aactccctgt atctgcaaat gaacaccctg agagacgagg acacggctgt gtattactgt 60 gcgagactgt tttactatga tagtagtgct tattacttgg gttactactt tgactactgg 120 ggccaggga 129 <210> 5311 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5311 Asn Ser Leu Tyr Leu Gln Met Asn Thr Leu Arg Asp Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Leu Phe Tyr Tyr Asp Ser Ser Ala Tyr Tyr 20 25 30 Leu Gly Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5312 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5312 Cys Ala Thr Asp Tyr Tyr Asp Ser Ser Gly Tyr Thr Trp Gly Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 5313 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5313 caagaactcc tgtatctgca aatgaacagt ctgagagctg aggacacggc cttgtattac 60 tgtgccacag attactatga tagtagtggt tacacgtggg ggtacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5314 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5314 Gln Glu Leu Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Leu Tyr Tyr Cys Ala Thr Asp Tyr Tyr Asp Ser Ser Gly Tyr Thr 20 25 30 Trp Gly Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5315 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5315 aagaactccc tgtatctgca aatgaacagt ctgagagctg aggacacggc cttgtattac 60 tgtgccacag attactatga tagtagtggt tacacgtggg ggtacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5316 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5316 Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Leu Tyr Tyr Cys Ala Thr Asp Tyr Tyr Asp Ser Ser Gly Tyr Thr 20 25 30 Trp Gly Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5317 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5317 Cys Ala Thr Asp Arg Pro Leu Thr Asp Tyr Tyr Tyr Gly Met Asp Val 1 5 10 15 Trp <210> 5318 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5318 gacacgtcta cagacacagc ctacatggag ctgagcagcc tgagatctga ggacacggcc 60 gtgtattact gtgcaacaga tcgcccgctt accgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5319 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5319 Asp Thr Ser Thr Asp Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Asp Arg Pro Leu Thr Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5320 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5320 gacacgtcta cagacacagc ctacatggag ctgagcagcc tgaaatctga ggacacggcc 60 gtgtattact gtgcaacaga tcgcccgctt accgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5321 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5321 Asp Thr Ser Thr Asp Thr Ala Tyr Met Glu Leu Ser Ser Leu Lys Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Asp Arg Pro Leu Thr Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5322 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5322 Cys Ala Lys Asp Leu Tyr Tyr Phe Asp Ser Ser Gly Tyr Asp Tyr Trp 1 5 10 15 <210> 5323 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5323 agagatgatt ccaagaacac gctgtatctg caaatgaaca gtctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatttatat tactttgata gtagtggtta tgactactgg 120 ggccaggga 129 <210> 5324 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5324 Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Tyr Tyr Phe 20 25 30 Asp Ser Ser Gly Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 5325 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5325 agagatgatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatttatat tactttgata gtagtggtta tgactactgg 120 ggccaggga 129 <210> 5326 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5326 Cys Ala Lys Ala Arg Ser Gly Tyr Asp Arg Phe Asp Tyr Trp 1 5 10 <210> 5327 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5327 atctccatac acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagcc cgcagtggct acgacagatt tgactactgg 120 ggccaggga 129 <210> 5328 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5328 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Arg Ser 20 25 30 Gly Tyr Asp Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5329 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5329 atctccagag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagcc cgcagtggct acgacagatt tgactactgg 120 ggccaggga 129 <210> 5330 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5330 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Arg Ser 20 25 30 Gly Tyr Asp Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5331 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5331 Cys Ala Lys Gly Glu Gly Ser Ser Trp Tyr Trp Phe Asp Pro Trp 1 5 10 15 <210> 5332 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5332 tccagagaca attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggctgtgt attactgtgc gaaaggtgag ggcagcagct ggtactggtt cgacccctgg 120 ggccaggga 129 <210> 5333 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5333 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Glu Gly Ser 20 25 30 Ser Trp Tyr Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5334 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5334 tacagagaca attccaagaa cacgctgtat ctgcaaatga accgcctgag agccgaggac 60 acggctgtgt attactgtgc gaaaggtgag ggcagcagct ggtactggtt cgacccctgg 120 ggccaggga 129 <210> 5335 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5335 Tyr Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Arg Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Glu Gly Ser 20 25 30 Ser Trp Tyr Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5336 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5336 Cys Ala His Thr Pro Pro Thr Thr Val Thr Thr Met Phe Asp Tyr Trp 1 5 10 15 <210> 5337 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5337 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca caccccgccg actacggtga ctacaatgtt tgactactgg 120 ggccaggga 129 <210> 5338 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5338 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Thr Pro Pro Thr Thr 20 25 30 Val Thr Thr Met Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5339 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5339 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca caccccgccg actacggtga ctacaatgtt tgactactgg 120 ggccaggga 129 <210> 5340 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5340 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Thr Pro Pro Thr Thr 20 25 30 Val Thr Thr Met Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5341 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5341 Cys Ala Lys Gly Pro Ala Ala Gly Thr Asp Trp 1 5 10 <210> 5342 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5342 cggttcacca tctccagata taattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaaggcc cagcagctgg taccgactgg 120 ggccaggga 129 <210> 5343 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5343 Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Gly Pro Ala Ala Gly Thr Asp Trp Gly Gln Gly 35 40 <210> 5344 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5344 cggttcacca tctccagaga taattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaaggcc cagcagctgg taccgactgg 120 ggccaggga 129 <210> 5345 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5345 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Gly Pro Ala Ala Gly Thr Asp Trp Gly Gln Gly 35 40 <210> 5346 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5346 Cys Ala Lys Asp Gly Ser Tyr Gly Ser Gln Pro Asn Leu Phe Asp Pro 1 5 10 15 Trp <210> 5347 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5347 gacaacgcca agaactccgt gtatttgcaa atgaacagtc tgagagctga ggacacggcc 60 ttgtattatt gtgcaaaaga tggatcctat gggtcccaac cgaacttatt cgacccctgg 120 ggccaggga 129 <210> 5348 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5348 Asp Asn Ala Lys Asn Ser Val Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Gly Ser Tyr Gly Ser 20 25 30 Gln Pro Asn Leu Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5349 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5349 gacaacgcca agaactccgt gtatttgcaa atgaacagtc tgagagctga ggacacggcc 60 ttatattatt gtgcaaaaga tggatcctat gggtcccaac cgaacttatt cgacccctgg 120 ggccaggga 129 <210> 5350 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5350 Cys Ala Arg Asp Ser Gly Glu Glu Tyr Cys Ser Gly Gly Ser Cys Tyr 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 5351 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5351 ctgcaaatga acagcctgaa aaccgaggac acggccgtgt attactgtgc tagagatagc 60 ggtgaggaat attgtagtgg tggtagctgc tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5352 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5352 Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Asp Ser Gly Glu Glu Tyr Cys Ser Gly Gly Ser Cys Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5353 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5353 ctgaaaatga actgcctgaa aaccgaggac acggccgtgt attactgtgc tagagatagc 60 ggtgaggaat attgtagtgg tggtagctgc tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5354 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5354 Leu Lys Met Asn Cys Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Asp Ser Gly Glu Glu Tyr Cys Ser Gly Gly Ser Cys Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5355 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5355 Cys Thr Ser Arg Ile Thr Met Val Thr Asn Arg Thr Glu Leu Phe Asp 1 5 10 15 Tyr Trp <210> 5356 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5356 ttttcaaaga acacggcgta tctgcaaatg aacagcctga aaaccgagga cacggccgtg 60 tattactgta ctagccgtat tactatggtt actaaccgca cggaattgtt tgactactgg 120 ggccaggga 129 <210> 5357 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5357 Phe Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Thr Ser Arg Ile Thr Met Val Thr Asn 20 25 30 Arg Thr Glu Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5358 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5358 gattcaaaga acacggcgta tctgcaaatg aacagcctga aaaccgagga cacggccgtg 60 tattactgta ctagccgtat tactatggtt actaaccgca cggaattgtt tgactactgg 120 ggccaggga 129 <210> 5359 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5359 Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Thr Ser Arg Ile Thr Met Val Thr Asn 20 25 30 Arg Thr Glu Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5360 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5360 Cys Ala Arg Glu Ala His Ser Ser Thr Trp Asp Asn Asn Phe Asp Leu 1 5 10 15 Trp <210> 5361 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5361 gacaacgcca agaacacgct gtatctgcag atgaacagtc tgagaaccgg ggacacggct 60 gtttatcact gtgcaagaga ggcgcatagc agcacctggg ataacaactt tgacctctgg 120 ggccaggga 129 <210> 5362 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5362 Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Thr 1 5 10 15 Gly Asp Thr Ala Val Tyr His Cys Ala Arg Glu Ala His Ser Ser Thr 20 25 30 Trp Asp Asn Asn Phe Asp Leu Trp Gly Gln Gly 35 40 <210> 5363 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5363 gacaacgcca agaacacgcc gtatctgcag atgaacagtc tgagaaccgg ggacacggct 60 gtttatcact gtgcaagaga ggcgcatagc agcacctggg ataacaactt tgacctctgg 120 ggccaggga 129 <210> 5364 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5364 Asp Asn Ala Lys Asn Thr Pro Tyr Leu Gln Met Asn Ser Leu Arg Thr 1 5 10 15 Gly Asp Thr Ala Val Tyr His Cys Ala Arg Glu Ala His Ser Ser Thr 20 25 30 Trp Asp Asn Asn Phe Asp Leu Trp Gly Gln Gly 35 40 <210> 5365 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5365 Cys Ala Arg Ala Ser Val Pro Tyr Tyr Tyr Asp Tyr Trp 1 5 10 <210> 5366 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5366 accatctcca tacacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gccagtgtac cttactacta tgactactgg 120 ggccaggga 129 <210> 5367 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5367 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Ser 20 25 30 Val Pro Tyr Tyr Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 5368 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5368 accatctcca gagacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gccagtgtac cttactacta tgactactgg 120 ggccaggga 129 <210> 5369 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5369 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Ser 20 25 30 Val Pro Tyr Tyr Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 5370 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5370 Cys Ala Arg Val Ile Ser Gly Ser Tyr Tyr Leu Asp Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 5371 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5371 tgcacagcct acttggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagtaa ttagtgggag ctactactta gactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5372 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5372 Cys Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Val Ile Ser Gly Ser Tyr Tyr Leu Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5373 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5373 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagtaa ttagtgggag ctactactta gactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5374 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5374 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Val Ile Ser Gly Ser Tyr Tyr Leu Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5375 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5375 Cys Ala Arg Asp His Gln Glu Met Ala Thr Ile Thr Trp Tyr Asp Ala 1 5 10 15 Phe Asp Ile Trp 20 <210> 5376 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5376 aagaacacgc tgtatctgca aatgaacagt ctgagagccg aggacacggc tgtgtattac 60 tgtgcaagag atcatcagga gatggctaca attacctggt atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5377 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5377 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Asp His Gln Glu Met Ala Thr Ile Thr 20 25 30 Trp Tyr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5378 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5378 aagaacacgc tgtatctgca aatgaacagt ctgagagccg aggacacggc tgcgtattac 60 tgtgcaagag atcatcagga gatggctaca attacctggt atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5379 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5379 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Ala Tyr Tyr Cys Ala Arg Asp His Gln Glu Met Ala Thr Ile Thr 20 25 30 Trp Tyr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5380 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5380 Cys Ala Lys Asp Ile Gly Gly Ser Ser Gly Trp Tyr Asp Glu Leu Gly 1 5 10 15 Trp Tyr Phe Asp Leu Trp 20 <210> 5381 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5381 tccctgtatc tgcaaatgaa cagtctgaga gctgaggaca cggccttgta ttactgtgca 60 aaagatatag gaggtagcag tggctggtac gatgaactgg gctggtactt cgatctctgg 120 ggccgtggc 129 <210> 5382 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5382 Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Ile Gly Gly Ser Ser Gly Trp Tyr Asp Glu 20 25 30 Leu Gly Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5383 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5383 tacatgtatc tgcaaatgaa cagtctgaga gctgaggaca cggccttgta ttactgtgca 60 aaagatatag gaggtagcag tggctggtac gatgaactgg gctggtactt cgatctctgg 120 ggccgtggc 129 <210> 5384 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5384 Tyr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Ile Gly Gly Ser Ser Gly Trp Tyr Asp Glu 20 25 30 Leu Gly Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5385 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5385 Cys Ala Arg Gly Asn Asp Gly Ser Ser Gly Ser His Phe Tyr Tyr Tyr 1 5 10 15 Tyr Gly Leu Asp Val Trp 20 <210> 5386 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5386 caattctccc tgaaagtgag ttctgtgacc gccgcggaca cggctgttta ttgctgtgcg 60 agaggcaatg acggcagcag cgggtctcat ttttattact actatggcct ggacgtctgg 120 ggccagggg 129 <210> 5387 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5387 Gln Phe Ser Leu Lys Val Ser Ser Val Thr Ala Ala Asp Thr Ala Val 1 5 10 15 Tyr Cys Cys Ala Arg Gly Asn Asp Gly Ser Ser Gly Ser His Phe Tyr 20 25 30 Tyr Tyr Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 5388 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5388 caattctccc tgaaagtgag ttctgtgacc gccgcggaca cggctgttta ttactgtgcg 60 agaggcaatg acggcagcag cgggtctcat ttttattact actatggcct ggacgtctgg 120 ggccagggg 129 <210> 5389 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5389 Gln Phe Ser Leu Lys Val Ser Ser Val Thr Ala Ala Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Asn Asp Gly Ser Ser Gly Ser His Phe Tyr 20 25 30 Tyr Tyr Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 5390 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5390 Cys Ala Lys Asp Asp Gly Val Ala Thr Ile Thr Ser Tyr Phe Asp Tyr 1 5 10 15 Trp <210> 5391 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5391 gacaacagca aaaactccct gtatctgcaa atgaacagtc tgagaactga ggacaccgcc 60 ttgtattact gtgcaaaaga cgacggggtg gctacaatta ctagctactt tgactactgg 120 ggccaggga 129 <210> 5392 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5392 Asp Asn Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Thr 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Asp Gly Val Ala Thr 20 25 30 Ile Thr Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5393 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5393 gacaacacca aaaactccct gtatctgcaa atgaacagtc tgagaactga ggacaccgcc 60 ttgtattact gtgcaaaaga cgacggggtg gctacaatta ctagctactt tgactactgg 120 ggccaggga 129 <210> 5394 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5394 Asp Asn Thr Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Thr 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Asp Gly Val Ala Thr 20 25 30 Ile Thr Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5395 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5395 Cys Ala Lys Glu Gly Tyr Tyr Asp Ile Leu Thr Gly Tyr Phe Trp Gln 1 5 10 15 Gly Leu Phe Asp Tyr Trp 20 <210> 5396 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5396 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagaagggt attacgatat tttgactggt tatttctggc aaggcctctt tgactactgg 120 ggccaggga 129 <210> 5397 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5397 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Glu Gly Tyr Tyr Asp Ile Leu Thr Gly Tyr Phe 20 25 30 Trp Gln Gly Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5398 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5398 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagaagggt attacgatat tttgactggt tatttctggc aaggcctctt tgactactgg 120 ggccaggga 129 <210> 5399 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5399 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Glu Gly Tyr Tyr Asp Ile Leu Thr Gly Tyr Phe 20 25 30 Trp Gln Gly Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5400 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5400 Cys Ala Lys Gly Arg Gly Pro Thr Met Thr Thr Ala Phe Asn Arg Phe 1 5 10 15 Asp Pro Trp <210> 5401 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5401 gccaagaact ccttgtttct gcaaatggac agtctgcgag ttgaggacac ggccttctat 60 tactgtgcaa aaggacgggg acctaccatg accactgctt ttaaccggtt cgacccctgg 120 ggccaggga 129 <210> 5402 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5402 Ala Lys Asn Ser Leu Phe Leu Gln Met Asp Ser Leu Arg Val Glu Asp 1 5 10 15 Thr Ala Phe Tyr Tyr Cys Ala Lys Gly Arg Gly Pro Thr Met Thr Thr 20 25 30 Ala Phe Asn Arg Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5403 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5403 gccaagaact ccctgtttct gcaaatggac agtctgcgag ttgaggacac ggccctctat 60 tactgtgcaa aaggacgggg acctaccatg accactgctt ttaaccggtt cgacccctgg 120 ggccaggga 129 <210> 5404 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5404 Ala Lys Asn Ser Leu Phe Leu Gln Met Asp Ser Leu Arg Val Glu Asp 1 5 10 15 Thr Ala Leu Tyr Tyr Cys Ala Lys Gly Arg Gly Pro Thr Met Thr Thr 20 25 30 Ala Phe Asn Arg Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5405 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5405 Cys Ala Arg Lys Leu Met Gly Thr Gln Pro Phe Asp Tyr Trp 1 5 10 <210> 5406 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5406 atgaccaggg acacgtccat cagcacagcc tacatggagc tcagcagcct gagatctggc 60 gacacggccg tgtattactg tgcgaggaaa ctaatgggaa cacaaccctt cgactactgg 120 ggccaggga 129 <210> 5407 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5407 Met Thr Arg Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Lys Leu Met 20 25 30 Gly Thr Gln Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5408 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5408 atgaccaggg acacgtccat cagcacagcc tacatggagc tcagcagcct gagatctgac 60 gacacggccg tgtattactg tgcgaggaaa ctaatgggaa cacaaccctt tgactactgg 120 ggccaggga 129 <210> 5409 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5409 Met Thr Arg Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Lys Leu Met 20 25 30 Gly Thr Gln Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5410 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5410 Cys Ala Lys Glu Val Arg Gly Val Ile Asp Tyr Trp 1 5 10 <210> 5411 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5411 ttcaccatct ccagatataa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagaggttc ggggagttat tgactactgg 120 ggccaggga 129 <210> 5412 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5412 Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu 20 25 30 Val Arg Gly Val Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 5413 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5413 ttcaccatct ccagagataa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagaggttc ggggagttat tgactactgg 120 ggccaggga 129 <210> 5414 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5414 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu 20 25 30 Val Arg Gly Val Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 5415 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5415 Cys Val Lys Gln Ser Ser Gly Asn Ser Tyr Gly Val Ser Asp Tyr Trp 1 5 10 15 <210> 5416 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5416 agatataatt ccaacaacac gctctacttg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgtgaa acagtcgagt gggaactcct acggggtttc ggactactgg 120 ggccaggga 129 <210> 5417 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5417 Arg Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Val Lys Gln Ser Ser Gly Asn 20 25 30 Ser Tyr Gly Val Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 5418 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5418 agagataatt ccaagaacac gctctacttg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgtgaa acagtcgagt gggaactcct acggggtttc ggactactgg 120 ggccaggga 129 <210> 5419 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5419 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Val Lys Gln Ser Ser Gly Asn 20 25 30 Ser Tyr Gly Val Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 5420 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5420 Cys Ala Arg Pro Arg Ala Pro Thr Thr Asn Tyr Tyr Tyr Tyr Gly Met 1 5 10 15 Asp Val Trp <210> 5421 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5421 tctgtcagca cggcatatct gcagatcagc agcctaaagg ctgaggacac tgccgtgtat 60 tactgtgcga ggccacgggc acctaccaca aactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5422 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5422 Ser Val Ser Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Pro Arg Ala Pro Thr Thr Asn Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5423 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5423 tctgtcagca cggcatatct gcagatcagc agcctaaagg ctgaggacac tgccgtgtat 60 tactgtgcga ggccacgggc acctaccaca aactactact actacggtat ggacgtctgg 120 agccaaggg 129 <210> 5424 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5424 Ser Val Ser Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Pro Arg Ala Pro Thr Thr Asn Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Ser Gln Gly 35 40 <210> 5425 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5425 Cys Ala Lys Glu Glu Gly Val Ser Thr Trp Thr Arg Ile Glu Asn Trp 1 5 10 15 <210> 5426 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5426 agatataatt ccatgaacat gctctatctg caaatgaaca gcctgagagg cgaggacacg 60 gccgtatatt actgtgcgaa agaagaggga gtcagtacct ggacgcggat tgagaactgg 120 ggccaggga 129 <210> 5427 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5427 Arg Tyr Asn Ser Met Asn Met Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Gly Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Glu Gly Val Ser 20 25 30 Thr Trp Thr Arg Ile Glu Asn Trp Gly Gln Gly 35 40 <210> 5428 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5428 agagataatt ccatgaacat gctctatctg caaatgaaca gcctgagagg cgaggacacg 60 gccgtatatt actgtgcgaa agaagaggga gtcagtacct ggacgcggat tgagaactgg 120 ggccaggga 129 <210> 5429 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5429 Arg Asp Asn Ser Met Asn Met Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Gly Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Glu Gly Val Ser 20 25 30 Thr Trp Thr Arg Ile Glu Asn Trp Gly Gln Gly 35 40 <210> 5430 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5430 Cys Ala Ser Leu Leu Gly Gly Ser Ala Thr Phe Asp Tyr Trp 1 5 10 <210> 5431 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5431 atctccagag acgacgccaa gaactcgttg tatctgcaaa tgaacagtct gagagtcgag 60 gacacggcta tgtattactg tgcaagccta ctaggaggga gtgccacttt cgactactgg 120 ggccaggga 129 <210> 5432 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5432 Ile Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Val Glu Asp Thr Ala Met Tyr Tyr Cys Ala Ser Leu Leu Gly 20 25 30 Gly Ser Ala Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5433 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5433 atctccagag acaacgccaa gaactcgttg tatctgcaaa tgaacagtct gagagtcgag 60 gacacggcta tgtattactg tgcaagccta ctaggaggga gtgccacttt cgactactgg 120 ggccaggga 129 <210> 5434 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5434 Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Val Glu Asp Thr Ala Met Tyr Tyr Cys Ala Ser Leu Leu Gly 20 25 30 Gly Ser Ala Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5435 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5435 Cys Ala Arg Glu Gly Tyr Ser Tyr Tyr Tyr Asp Ser Ser Gly Gln Asn 1 5 10 15 Trp Phe Asp Pro Trp 20 <210> 5436 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5436 tgcacagcct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagagg gctactcgta ttactatgat agtagtggtc agaactggtt cgacccctgg 120 ggccaggga 129 <210> 5437 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5437 Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Gly Tyr Ser Tyr Tyr Tyr Asp Ser Ser 20 25 30 Gly Gln Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5438 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5438 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagagg gctactcgta ttactatgat agtagtggtc agaactggtt cgacccctgg 120 ggccaggga 129 <210> 5439 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5439 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Gly Tyr Ser Tyr Tyr Tyr Asp Ser Ser 20 25 30 Gly Gln Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5440 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5440 Cys Ala Lys Leu Met Gly Gly Gly Asp Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 5441 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5441 tccagagaca attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaattgatg ggaggtggtg actactactt tgactactgg 120 ggccaggga 129 <210> 5442 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5442 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Leu Met Gly Gly 20 25 30 Gly Asp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5443 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5443 tccacagaca attccaacaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaattgatg ggaggtggtg actactactt tgactactgg 120 ggccaggga 129 <210> 5444 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5444 Ser Thr Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Leu Met Gly Gly 20 25 30 Gly Asp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5445 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5445 Cys Ala Lys Ala Arg Tyr Ser Ser Ser Trp Tyr Glu Thr Arg Asp Tyr 1 5 10 15 Tyr Tyr Gly Met Asp Val Trp 20 <210> 5446 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5446 ctgtatctgc aaatgaacag cctgagagcc gaggacacgg ccgtatatta ctgtgcgaaa 60 gcgaggtata gcagcagctg gtacgaaacc cgtgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5447 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5447 Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Lys Ala Arg Tyr Ser Ser Ser Trp Tyr Glu Thr Arg Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5448 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5448 ctgcatctgc aaatgaacag cctgagagcc gaggacacgg ccgtatatta ctgtgcgaaa 60 gcgaggtata gcagcagctg gtacgaaacc cgtgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5449 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5449 Leu His Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Lys Ala Arg Tyr Ser Ser Ser Trp Tyr Glu Thr Arg Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5450 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5450 Cys Ala Lys Asp Gly Thr Met Val Arg Glu Arg Arg Pro Phe Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 5451 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5451 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggctgtgta ttactgtgcg 60 aaagatggga ctatggttcg ggagcgccgt cctttctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5452 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5452 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Gly Thr Met Val Arg Glu Arg Arg Pro Phe 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5453 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5453 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggctgtgta ttactgtgcg 60 aaagatggga ctatggttcg ggagcgccgt cctttctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5454 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5454 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Gly Thr Met Val Arg Glu Arg Arg Pro Phe 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5455 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5455 Cys Ala Lys Ala Pro Pro Asn Arg Pro Gly Gly Arg Ala Gln Phe Arg 1 5 10 15 Tyr Phe Asp Tyr Trp 20 <210> 5456 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5456 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagcac cccccaatag gccgggtggt cgggctcagt tccgctactt tgactactgg 120 ggccaggga 129 <210> 5457 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5457 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Ala Pro Pro Asn Arg Pro Gly Gly Arg Ala 20 25 30 Gln Phe Arg Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5458 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5458 Cys Ala Arg His Ser Gly Ser Ser Trp Tyr Asp Ala Phe Asp Ile Trp 1 5 10 15 <210> 5459 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5459 gtagacacgt ccaagaacca gttctccctg aagctgagct ctgtgaccgc cgcagacacg 60 gctgtgtatt actgtgcgag acattcgggc agcagctggt acgatgcttt tgatatctgg 120 ggtcaaggg 129 <210> 5460 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5460 Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg His Ser Gly Ser Ser 20 25 30 Trp Tyr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5461 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5461 gtagacacgt ccaagaacca gttctccctg aagctgagct ctgtgaccgc cgcagacacg 60 gctgtgtatt actgtgcgag acattcgggc agcagctggt acgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5462 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5462 Cys Ala Lys Val Gly Tyr Tyr Asp Ser Ser Gly Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 5463 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5463 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gtcgtatatt actgtgcgaa agtaggctac tatgatagta gtggttattt tgactactgg 120 ggccaggga 129 <210> 5464 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5464 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Val Val Tyr Tyr Cys Ala Lys Val Gly Tyr Tyr Asp 20 25 30 Ser Ser Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5465 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5465 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agtaggctac tatgatagta gtggttattt tgactactgg 120 ggccaggga 129 <210> 5466 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5466 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Tyr Tyr Asp 20 25 30 Ser Ser Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5467 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5467 Cys Ala Lys Glu Gly Arg Ser Asp Tyr Trp 1 5 10 <210> 5468 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5468 ggccgattca ccatctccag agacaacgcc aagaactccc tgtatctgca aatgaacagt 60 ctgagagctg aggacacggc cttgtattac tgtgcaaaag agggacgttc agactactgg 120 ggccaggga 129 <210> 5469 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5469 Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu 1 5 10 15 Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala 20 25 30 Lys Glu Gly Arg Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 5470 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5470 ggccgattca ccatctccag agacaacgcc aagaactccc tgtatctgca aatgaacagt 60 ctgagagctg aggacacggc cttgtattac tgcgcaaaag agggacgttc agactactgg 120 ggccaggga 129 <210> 5471 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5471 Cys Ala Arg Ser Tyr Asp Ser Ser Gly Tyr Ser Asp Tyr Trp 1 5 10 <210> 5472 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5472 atctcagccg gcgagtccat cagcaccgcc tacctgcagt ggagcagcct gaaggcctcg 60 gacaccgcca tgtattactg tgcgagatcc tatgatagta gtggttattc tgactactgg 120 ggccaggga 129 <210> 5473 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5473 Ile Ser Ala Gly Glu Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser 1 5 10 15 Leu Lys Ala Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Ser Tyr Asp 20 25 30 Ser Ser Gly Tyr Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 5474 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5474 atctcagccg acaagtccat cagcaccgcc tacctgcagt ggagcagcct gaaggcctcg 60 gacaccgcca tgtattactg tgcgagatcc tatgatagta gtggttattc tgactactgg 120 ggccaggga 129 <210> 5475 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5475 Ile Ser Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser 1 5 10 15 Leu Lys Ala Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Ser Tyr Asp 20 25 30 Ser Ser Gly Tyr Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 5476 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5476 Cys Ala Arg Gly Pro Val Gly Ala Ala Val Val Ala Ala Thr Arg Phe 1 5 10 15 Asp Pro Trp <210> 5477 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5477 tccgcgaaca cggcctacat ggaattgaga ggcctgacat ctgaagacac ggctatcttt 60 ttctgtgcga gagggcccgt gggtgcagcg gtggtagctg ccactcgctt cgacccgtgg 120 ggccaggga 129 <210> 5478 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5478 Ser Ala Asn Thr Ala Tyr Met Glu Leu Arg Gly Leu Thr Ser Glu Asp 1 5 10 15 Thr Ala Ile Phe Phe Cys Ala Arg Gly Pro Val Gly Ala Ala Val Val 20 25 30 Ala Ala Thr Arg Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5479 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5479 tccgcgaaca cggcctacat ggaattgaga ggcctgaaat ctgaagacac gggtatcttt 60 ttctgtgcga gagggcccgt gggtgcagcg gtggtagctg ccactcgctt cgacccgtgg 120 ggccaggga 129 <210> 5480 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5480 Ser Ala Asn Thr Ala Tyr Met Glu Leu Arg Gly Leu Lys Ser Glu Asp 1 5 10 15 Thr Gly Ile Phe Phe Cys Ala Arg Gly Pro Val Gly Ala Ala Val Val 20 25 30 Ala Ala Thr Arg Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5481 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5481 Cys Ala Arg Ile Tyr Gly Asp Leu Tyr Tyr Gly Met Asp Val Trp 1 5 10 15 <210> 5482 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5482 tcagccgaca agtccatcag caccgcctac ctgcagtgga gcggcctgaa ggcctcggac 60 accgccatgt attactgcgc gagaatctac ggtgacttat actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5483 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5483 Ser Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Gly Leu 1 5 10 15 Lys Ala Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Ile Tyr Gly Asp 20 25 30 Leu Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5484 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5484 tcagccgaca agtccatcag caccgcctac ctgcagtgga gcagcctgaa ggcctcggac 60 accgccatgt attactgtgc gagaatctac ggtgacttat actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5485 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5485 Ser Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu 1 5 10 15 Lys Ala Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Ile Tyr Gly Asp 20 25 30 Leu Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5486 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5486 Cys Thr Thr Asp Ile Ser Ser Pro His Ala Leu Trp Phe Gly Glu Thr 1 5 10 15 Asp Tyr Trp <210> 5487 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5487 tcaaaaaaca cgctgtatct gcaaatgaac agcctgaaaa ccgaggacac agccgtgtat 60 tactgtacca cagatataag ctctccgcat gcactatggt tcggggagac tgactactgg 120 ggccaggga 129 <210> 5488 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5488 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Thr Asp Ile Ser Ser Pro His Ala Leu 20 25 30 Trp Phe Gly Glu Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 5489 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5489 ttcaaaaaca cgctgtatct gcaaatgaac agcctgaaaa ccgaggacac agccgtgtat 60 tactgtacca cagatataag ctctccgcat gcactatggt tcggggagac tgactactgg 120 ggccaggga 129 <210> 5490 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5490 Phe Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Thr Asp Ile Ser Ser Pro His Ala Leu 20 25 30 Trp Phe Gly Glu Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 5491 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5491 Cys Ala Lys Asp Gly Leu Val Val Ala Gly Thr Phe Asp Tyr Trp 1 5 10 15 <210> 5492 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5492 tccagatata attccaagaa cacgctgtat ctgaaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaagatgga ctagtggtgg ctggtacctt tgactactgg 120 ggccaggga 129 <210> 5493 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5493 Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Lys Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Gly Leu Val 20 25 30 Val Ala Gly Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5494 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5494 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaagatgga ctagtggtgg ctggtacctt tgactactgg 120 ggccaggga 129 <210> 5495 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5495 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Gly Leu Val 20 25 30 Val Ala Gly Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5496 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5496 Cys Thr Ser Ala Tyr Ser Ser Ser Trp Tyr Tyr Tyr Tyr Gly Met Asp 1 5 10 15 Val Trp <210> 5497 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5497 gattcaacca acacggcgta tctgcaaatg aacagcctga aaaccgagga cacggccgtg 60 tattactgta ctagcgcgta tagcagcagc tggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5498 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5498 Asp Ser Thr Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Thr Ser Ala Tyr Ser Ser Ser Trp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5499 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5499 gattcaaaga acacggcgta tctgcaaatg aacagcctga aaaccgagga cacggccgtg 60 tattactgta ctagcgcgta tagcagcagc tggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5500 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5500 Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Thr Ser Ala Tyr Ser Ser Ser Trp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5501 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5501 Cys Ala Arg Leu Leu Val Val Tyr Ala Tyr Phe Asp Tyr Trp 1 5 10 <210> 5502 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5502 atctccatac acaattccaa gaacacgctg tatcttcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagacta ctggtggtgt atgcctactt tgactactgg 120 ggccaggga 129 <210> 5503 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5503 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu Val 20 25 30 Val Tyr Ala Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5504 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5504 atctccagag acaattccaa gaacacgctg tatcttcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagacta ctggtggtgt atgcctactt tgactactgg 120 ggccaggga 129 <210> 5505 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5505 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Leu Val 20 25 30 Val Tyr Ala Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5506 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5506 Cys Ala Arg Gln Glu Asn Ser Gly Ser Phe Gln Ile Thr His Phe Asp 1 5 10 15 Tyr Trp <210> 5507 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5507 agctccagca gcaccgccta cctgcagtgg agcagcctga aggcctcgga caccgccatg 60 tattactgtg cgagacaaga aaatagtggg agcttccaaa taacacactt tgactactgg 120 ggccaggga 129 <210> 5508 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5508 Ser Ser Ser Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser 1 5 10 15 Asp Thr Ala Met Tyr Tyr Cys Ala Arg Gln Glu Asn Ser Gly Ser Phe 20 25 30 Gln Ile Thr His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5509 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5509 aagtccatca gcaccgccta cctgcagtgg agcagcctga aggcctcgga caccgccatg 60 tattactgtg cgagacaaga aaatagtggg agcttccaaa taacacactt tgactactgg 120 ggccaggga 129 <210> 5510 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5510 Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser 1 5 10 15 Asp Thr Ala Met Tyr Tyr Cys Ala Arg Gln Glu Asn Ser Gly Ser Phe 20 25 30 Gln Ile Thr His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5511 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5511 Cys Ala Lys Gly Pro Tyr Gly Asp Asp Arg Phe Phe Phe Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 5512 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5512 aagaacacac tgtggctgca aatggacagc ctgagagccg gggacacggc catatattac 60 tgtgcgaaag gtccctacgg tgacgaccga ttcttcttct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5513 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5513 Lys Asn Thr Leu Trp Leu Gln Met Asp Ser Leu Arg Ala Gly Asp Thr 1 5 10 15 Ala Ile Tyr Tyr Cys Ala Lys Gly Pro Tyr Gly Asp Asp Arg Phe Phe 20 25 30 Phe Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5514 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5514 aagaacacac tgtggctgca aatgaacagc ctgagagccg aggacacggc catatattac 60 tgtgcgaaag gtccctacgg tgacgaccga ttcttcttct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5515 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5515 Lys Asn Thr Leu Trp Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Ile Tyr Tyr Cys Ala Lys Gly Pro Tyr Gly Asp Asp Arg Phe Phe 20 25 30 Phe Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5516 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5516 Cys Ala Arg Gly Gly Gly Lys Tyr Tyr Tyr Gly Ser Gly Arg His Tyr 1 5 10 15 Tyr Tyr Tyr Gly Met Asp Val Trp 20 <210> 5517 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5517 tccctgaagc tgagctctgt gaccgccgcg gactcggctg tgtattactg tgcgagagga 60 ggggggaaat attactatgg ttcggggagg cactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5518 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5518 Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Ser Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Gly Gly Gly Lys Tyr Tyr Tyr Gly Ser Gly Arg His Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5519 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5519 tccctgaagc tgagctctgt gaccgccgcg gacacggctg tgtattactg tgcgagagga 60 ggggggaaat attactatgg ttcggggagg cactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5520 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5520 Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Gly Gly Gly Lys Tyr Tyr Tyr Gly Ser Gly Arg His Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5521 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5521 Cys Ala Arg Asp Arg Asp Tyr Asp Asp Thr Ser Asn Tyr Tyr His Gly 1 5 10 15 Gly Tyr Phe Asp Ser Trp 20 <210> 5522 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5522 tccctatatc tgcaaatgaa cggtctgaga gccgaggaca cggccctcta ttactgtgcg 60 agagatcgtg attatgatga tacgagtaat tattaccacg gcgggtactt tgactcctgg 120 ggccaggga 129 <210> 5523 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5523 Ser Leu Tyr Leu Gln Met Asn Gly Leu Arg Ala Glu Asp Thr Ala Leu 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Arg Asp Tyr Asp Asp Thr Ser Asn Tyr Tyr 20 25 30 His Gly Gly Tyr Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 5524 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5524 tccatatatc tgcaaatgaa cggtctgaga gccgaggaca cggccctcta ttactgtgcg 60 agagatcgtg attatgatga tacgagtaat tattaccacg gcgggtactt tgactcctgg 120 ggccaggga 129 <210> 5525 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5525 Ser Ile Tyr Leu Gln Met Asn Gly Leu Arg Ala Glu Asp Thr Ala Leu 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Arg Asp Tyr Asp Asp Thr Ser Asn Tyr Tyr 20 25 30 His Gly Gly Tyr Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 5526 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5526 Cys Ala Arg Asp Gly Thr Gln Leu Val Leu Asp Leu His Ala Phe Asp 1 5 10 15 Ile Trp <210> 5527 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5527 aaatccacgt gcacagccta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagagatgg aacgcagctg gtactggatc tacatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5528 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5528 Lys Ser Thr Cys Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Gly Thr Gln Leu Val Leu 20 25 30 Asp Leu His Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5529 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5529 aaatccacga gcacagccta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagagatgg aacgcagctg gtactggatc tacatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5530 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5530 Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Gly Thr Gln Leu Val Leu 20 25 30 Asp Leu His Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5531 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5531 Cys Ala Ser Gly Gly Val Arg Gly Val Ile Met Val Tyr Trp 1 5 10 <210> 5532 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5532 ttatcagtag acacgtccaa gaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggctg tgtattactg tgcgagcggg ggggttcggg gagttattat ggtctactgg 120 ggccaggga 129 <210> 5533 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5533 Leu Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly Gly Val 20 25 30 Arg Gly Val Ile Met Val Tyr Trp Gly Gln Gly 35 40 <210> 5534 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5534 atatcagtag acacgtccaa gaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggctg tgtattactg tgcgagcggg ggggttcggg gagttattat ggtctactgg 120 ggccaggga 129 <210> 5535 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5535 Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly Gly Val 20 25 30 Arg Gly Val Ile Met Val Tyr Trp Gly Gln Gly 35 40 <210> 5536 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5536 Cys Ala Arg Gly Leu Arg Ser Pro Pro His Thr Ala Ser Lys Thr Pro 1 5 10 15 Lys Lys Tyr Trp Tyr Phe Asp Leu Trp 20 25 <210> 5537 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5537 ttggagctga gcagcctgag atctgaggac acggccgtgt attactgtgc gagaggcctt 60 cgttcccccc cccatacggc atcgaaaacc ccgaagaaat actggtactt cgatctctgg 120 ggccgtggc 129 <210> 5538 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5538 Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Leu Arg Ser Pro Pro His Thr Ala Ser Lys Thr Pro Lys 20 25 30 Lys Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5539 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5539 atggagctga gcagcctgag atctgaggac acggccgtgt attactgtgc gagaggcctt 60 cgttcccccc cccatacggc atcgaaaacc ccgaagaaat actggtactt cgatctctgg 120 ggccgtggc 129 <210> 5540 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5540 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Leu Arg Ser Pro Pro His Thr Ala Ser Lys Thr Pro Lys 20 25 30 Lys Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5541 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5541 Cys Ala Arg Gly Thr Thr Val Val Thr Gly Phe Asp Tyr Trp 1 5 10 <210> 5542 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5542 catcaaccca gacacatcca agaaccagtt ctcctgcagc tgaactctgt gactcccgag 60 gacacggctg tgtattactg tgcaaggggg actacggtgg taacggggtt cgactactgg 120 ggccaggga 129 <210> 5543 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5543 His Gln Pro Arg His Ile Gln Glu Pro Val Leu Leu Gln Leu Asn Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Thr Thr 20 25 30 Val Val Thr Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5544 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5544 atcaacccag acacatccaa gaaccagttc tccctgcagc tgaactctgt gactcccgag 60 gacacggctg tgtattactg tgcaaggggg actacggtgg taacggggtt cgactactgg 120 ggccaggga 129 <210> 5545 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5545 Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Thr Thr 20 25 30 Val Val Thr Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5546 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5546 Cys Ala Arg Glu Pro Arg Tyr Trp 1 5 <210> 5547 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5547 gtgaagggcc tattcaccat ctccagagac aattccaaga acacgctgta tcttcaaatg 60 aacagcctga gagccgagga cacggccgtg tattactgtg cgagagagcc ccgatactgg 120 ggccaggga 129 <210> 5548 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5548 Val Lys Gly Leu Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu 1 5 10 15 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 20 25 30 Cys Ala Arg Glu Pro Arg Tyr Trp Gly Gln Gly 35 40 <210> 5549 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5549 gtgaagggcc gattcaccat ctccagagac aattccaaga acacgctgta tcttcaaatg 60 aacagcctga gagccgagga cacggccgtg tattactgtg cgagagagcc ccgatactgg 120 ggccaggga 129 <210> 5550 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5550 Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu 1 5 10 15 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 20 25 30 Cys Ala Arg Glu Pro Arg Tyr Trp Gly Gln Gly 35 40 <210> 5551 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5551 Cys Ala Ser Ser Pro Trp Asp Ser Arg Thr Ser Leu Trp 1 5 10 <210> 5552 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5552 accatgacca gggacacgtc catcagcacg gcctacatgg agctgagcag gctgagatct 60 gacgacacgg ccgtgtatta ctgtgcgagt tccccctggg atagtaggac ctccctctgg 120 ggccaggga 129 <210> 5553 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5553 Thr Met Thr Arg Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Arg Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Ser Ser Pro 20 25 30 Trp Asp Ser Arg Thr Ser Leu Trp Gly Gln Gly 35 40 <210> 5554 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5554 accatgacca gggacacgtc catcagcaca gcctacatgg agctgagcag gctgagatct 60 gacgacacgg ccgtgtatta ctgtgcgagt tccccctggg atagtaggac ctccctctgg 120 ggccaggga 129 <210> 5555 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5555 Cys Ala Arg Gly Leu Lys Val Asp Thr Ala Met Val Arg Val Ala Leu 1 5 10 15 Gly Met Asp Val Trp 20 <210> 5556 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5556 aaccagttct ccctggagct gagctctgtg accgccgcgg acacggctgt ggattactgt 60 gcgagaggcc ttaaggtgga tacagctatg gttagagtag cactcggtat ggacgtctgg 120 ggccaaggg 129 <210> 5557 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5557 Asn Gln Phe Ser Leu Glu Leu Ser Ser Val Thr Ala Ala Asp Thr Ala 1 5 10 15 Val Asp Tyr Cys Ala Arg Gly Leu Lys Val Asp Thr Ala Met Val Arg 20 25 30 Val Ala Leu Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5558 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5558 aaccagttct ccctgaagct gagctctgtg accgccgcgg acacggctgt gtattactgt 60 gcgagaggcc ttaaggtgga tacagctatg gttagagtag cactcggtat ggacgtctgg 120 ggccaaggg 129 <210> 5559 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5559 Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Leu Lys Val Asp Thr Ala Met Val Arg 20 25 30 Val Ala Leu Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5560 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5560 Cys Ala Lys Ser Leu Gly Arg Ser Trp Tyr Asn Pro Arg His Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 5561 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5561 tacacgatgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaatccc tgggccgcag ctggtacaat ccgcggcact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5562 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5562 Tyr Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Ser Leu Gly Arg Ser Trp Tyr Asn Pro Arg 20 25 30 His Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5563 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5563 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaatccc tgggccgcag ctggtacaat ccgcggcact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5564 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5564 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Ser Leu Gly Arg Ser Trp Tyr Asn Pro Arg 20 25 30 His Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5565 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5565 Cys Ala Arg Arg Asn Tyr Tyr Ala Ser Gly Ser Pro Ser Tyr Trp Tyr 1 5 10 15 Phe Asp Leu Trp 20 <210> 5566 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5566 aagaacacgc tgtctcttca aatgaacagc ctgagagccg aggacgcggc catttattat 60 tgtgcgagac ggaattacta tgcctcgggg agcccctcgt attggtactt cgatctctgg 120 ggccgtggc 129 <210> 5567 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5567 Lys Asn Thr Leu Ser Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Ala 1 5 10 15 Ala Ile Tyr Tyr Cys Ala Arg Arg Asn Tyr Tyr Ala Ser Gly Ser Pro 20 25 30 Ser Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5568 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5568 aagaacacgc tgtctcttca aatgaacagc ctgagagccg aggacacggc catttattat 60 tgtgcgagac ggaattacta tgcctcgggg agcccctcgt attggtactt cgatctctgg 120 ggccgtggc 129 <210> 5569 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5569 Lys Asn Thr Leu Ser Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Ile Tyr Tyr Cys Ala Arg Arg Asn Tyr Tyr Ala Ser Gly Ser Pro 20 25 30 Ser Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5570 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5570 Cys Ala Lys Asp Phe Arg Arg Ile Val Val Val Val Ala Ser Thr Leu 1 5 10 15 His Tyr Tyr Gly Met Asp Val Trp 20 <210> 5571 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5571 tatctgcaaa tgaacagtct gagagtcgag gacacggccg tgtattactg tgcaaaagat 60 tttcgccgta ttgtagtggt ggtagcttct actctacact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5572 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5572 Tyr Leu Gln Met Asn Ser Leu Arg Val Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Phe Arg Arg Ile Val Val Val Val Ala Ser Thr Leu 20 25 30 His Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5573 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5573 tatatgaaaa tgaacagtct gagagtcgag gacacggccg tgtattactg tgcaaaagat 60 tttcgccgta ttgtagtggt ggtagcttct actctacact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5574 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5574 Tyr Met Lys Met Asn Ser Leu Arg Val Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Phe Arg Arg Ile Val Val Val Val Ala Ser Thr Leu 20 25 30 His Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5575 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5575 Cys Val Arg Gly His Tyr Asp Arg Ser Gly Ser Trp Gly Phe Asp Tyr 1 5 10 15 Trp <210> 5576 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5576 gacaatgcca ataactcttt gtatctgcaa atgaacaatc tgagagacga ggacacggct 60 ctatattatt gtgtgcgagg gcactatgat aggagtggtt cttggggctt tgactactgg 120 ggccaggga 129 <210> 5577 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5577 Asp Asn Ala Asn Asn Ser Leu Tyr Leu Gln Met Asn Asn Leu Arg Asp 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Val Arg Gly His Tyr Asp Arg Ser 20 25 30 Gly Ser Trp Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5578 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5578 gacaatgcca agaactcatt gtatctgcaa atgaacaatc tgagagacga ggacacggct 60 ctatattatt gtgtgcgagg gcactatgat aggagtggtt cttggggctt tgactactgg 120 ggccaggga 129 <210> 5579 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5579 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Asn Leu Arg Asp 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Val Arg Gly His Tyr Asp Arg Ser 20 25 30 Gly Ser Trp Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5580 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5580 Cys Ala Arg Ser Ser Gly Asp Phe Trp Ser Gly Tyr Pro Ser Leu Gly 1 5 10 15 Phe Asp Pro Trp 20 <210> 5581 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5581 gtcagcacgg catatctgca gatcagcagc ctaaaggctg aggacactgc cgtgtattac 60 tgtgcgagat cctccgggga tttttggagt ggttatccct cgctggggtt cgacccctgg 120 ggccaggga 129 <210> 5582 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5582 Val Ser Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Ser Ser Gly Asp Phe Trp Ser Gly Tyr 20 25 30 Pro Ser Leu Gly Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5583 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5583 gtcagcacgg catatccgca gatcagcagc ctgaaggctg aggacactgc cgtgtattac 60 tgtgcgagat cctccgggga tttttggagt ggttatccct cgctggggtt cgacccctgg 120 ggccaggga 129 <210> 5584 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5584 Val Ser Thr Ala Tyr Pro Gln Ile Ser Ser Leu Lys Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Ser Ser Gly Asp Phe Trp Ser Gly Tyr 20 25 30 Pro Ser Leu Gly Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5585 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5585 Cys Ala Arg Met Ala Ala Ala Ala Gly Gln Phe Asp Tyr Trp 1 5 10 <210> 5586 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5586 atctccatag aaaatgccaa gaactccttg tatcttcaaa tgaacagcct gagagccggt 60 gacacggctg tgtattactg tgcaagaatg gcggcagcag ctggccaatt tgactactgg 120 ggccaggga 129 <210> 5587 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5587 Ile Ser Ile Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Met Ala Ala 20 25 30 Ala Ala Gly Gln Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5588 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5588 atctccagag aaaatgccaa gaactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagaatg gcggcagcag ctggccaatt tgactactgg 120 ggccaggga 129 <210> 5589 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5589 Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Met Ala Ala 20 25 30 Ala Ala Gly Gln Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5590 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5590 Cys Ala Arg Lys Tyr Tyr Tyr Asp Ser Ser Gly Ser Tyr Asp Tyr Trp 1 5 10 15 <210> 5591 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5591 tgggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag gaagtattac tatgatagta gtggttccta tgactactgg 120 ggccaggga 129 <210> 5592 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5592 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Lys Tyr Tyr Tyr Asp 20 25 30 Ser Ser Gly Ser Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 5593 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5593 agggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag gaagtattac tatgatagta gtggttccta tgactactgg 120 ggccaggga 129 <210> 5594 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5594 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Lys Tyr Tyr Tyr Asp 20 25 30 Ser Ser Gly Ser Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 5595 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5595 Cys Ala His His Tyr Ser Ser Gly Trp Tyr Ile Ile Phe Asp Tyr Trp 1 5 10 15 <210> 5596 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5596 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca ccattatagc agtggctggt acataatctt tgactactgg 120 ggccaggga 129 <210> 5597 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5597 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His His Tyr Ser Ser Gly 20 25 30 Trp Tyr Ile Ile Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5598 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5598 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca ccattatagc agtggctggt acataatctt tgactactgg 120 ggccaggga 129 <210> 5599 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5599 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His His Tyr Ser Ser Gly 20 25 30 Trp Tyr Ile Ile Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5600 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5600 Cys Ala Arg Val Ser Ser Ser Trp Gly Tyr Trp Tyr Phe Asp Leu Trp 1 5 10 15 <210> 5601 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5601 ccagacacat ccaagaacca gttctccctg cagctgaact ctgtgactcc cgaggacacg 60 gctgtgtatt gctgtgcaag agttagcagc agctggggct actggtactt cgatctctgg 120 ggccgtggc 129 <210> 5602 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5602 Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser Val Thr 1 5 10 15 Pro Glu Asp Thr Ala Val Tyr Cys Cys Ala Arg Val Ser Ser Ser Trp 20 25 30 Gly Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5603 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5603 ccagacacat ccaagaacca gttctccctg cagctgaact ctgtgactcc cgaggacacg 60 gctgtgtatt actgtgcaag agttagcagc agctggggct actggtactt cgatctctgg 120 ggccgtggc 129 <210> 5604 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5604 Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser Val Thr 1 5 10 15 Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Ser Ser Ser Trp 20 25 30 Gly Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5605 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5605 Cys Ser Arg Gly Thr Arg Glu Leu Pro Asp Trp 1 5 10 <210> 5606 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5606 cgattcacca tctccagaga caacgccaag aactccctgt atctgcaaat gaatagtctg 60 agacctgagg acacggcctt atattactgt tcaagaggga ccagggagct gccggactgg 120 ggccaggga 129 <210> 5607 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5607 Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Pro Glu Asp Thr Ala Leu Tyr Tyr Cys Ser Arg 20 25 30 Gly Thr Arg Glu Leu Pro Asp Trp Gly Gln Gly 35 40 <210> 5608 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5608 cgattcacca tctccagaga caacgccaag aactccctgt atctgcaaat gaatagcctg 60 agacctgagg acacggcctt atattactgt tcaagaggga ccagggagct gccggactgg 120 ggccaggga 129 <210> 5609 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5609 Cys Ala Lys Asp Thr Ser Ile Glu Tyr Ser Ser Ala Ser Gly Gly Gly 1 5 10 15 Ser Phe Asp Tyr Trp 20 <210> 5610 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5610 aactccctgt atctgcaaat gaacagtctg agagctgagg acacggcctt gtattactgt 60 gcaaaagata cgagcatcga gtatagcagc gcgtccgggg ggggtagttt tgactactgg 120 ggccaggga 129 <210> 5611 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5611 Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Leu Tyr Tyr Cys Ala Lys Asp Thr Ser Ile Glu Tyr Ser Ser Ala Ser 20 25 30 Gly Gly Gly Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5612 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5612 Cys Ala Arg Asp Trp Gly Tyr Ser Tyr Gly Tyr Arg Gly Trp Tyr Leu 1 5 10 15 Asp Leu Trp <210> 5613 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5613 tctgtcggca cgacatatct gcagatcagc agcctaaagg ctggggacac tgccgtgtat 60 tactgtgcga gagattgggg atacagctat ggttacaggg gctggtacct cgatctctgg 120 ggccgtggc 129 <210> 5614 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5614 Ser Val Gly Thr Thr Tyr Leu Gln Ile Ser Ser Leu Lys Ala Gly Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Asp Trp Gly Tyr Ser Tyr Gly Tyr 20 25 30 Arg Gly Trp Tyr Leu Asp Leu Trp Gly Arg Gly 35 40 <210> 5615 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5615 tctgtcggca cgacatatct gcagatcagc agcctaaagg ctgaggacac tgccgtgtat 60 tactgtgcga gagattgggg atacagctat ggttacaggg gctggtacct cgatctctgg 120 ggccgtggc 129 <210> 5616 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5616 Ser Val Gly Thr Thr Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Asp Trp Gly Tyr Ser Tyr Gly Tyr 20 25 30 Arg Gly Trp Tyr Leu Asp Leu Trp Gly Arg Gly 35 40 <210> 5617 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5617 Cys Ala Arg Val Ser Trp Val Arg Met Gly Ala Thr Arg Gly Tyr Tyr 1 5 10 15 Tyr Tyr Gly Met Asp Val Trp 20 <210> 5618 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5618 ctgtatctac aaatgaacag cctgaaaacc gaggacacgg ccgtgtatta ctgtgctaga 60 gtctcgtggg tcagaatggg agctactcgg ggatactatt actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5619 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5619 Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Val Ser Trp Val Arg Met Gly Ala Thr Arg Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5620 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5620 ctgtatatac aattgaacag cctgaaaacc gaggacacgg ccgtgtatta ctgtgctaga 60 gtctcgtggg tcagaatggg agctactcgg ggatactatt actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5621 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5621 Leu Tyr Ile Gln Leu Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Val Ser Trp Val Arg Met Gly Ala Thr Arg Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5622 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5622 Cys Thr Arg His Gly Tyr Asp Ile Leu Thr Gly Tyr Tyr Glu Thr His 1 5 10 15 Asp Ala Phe Asp Ile Trp 20 <210> 5623 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5623 acggcgtatc tgcaaatgaa cagcctgaaa accgaggaca cggccgtgta ttactgtact 60 agacatggtt acgatatttt gactggttat tatgaaaccc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5624 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5624 Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Thr Arg His Gly Tyr Asp Ile Leu Thr Gly Tyr Tyr Glu 20 25 30 Thr His Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5625 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5625 acggcgtatc tgaaaatgaa cagcctgaaa accgaggaca cggccgtgta ttactgtact 60 agacatggtt acgatatttt gactggttat tatgaaaccc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5626 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5626 Thr Ala Tyr Leu Lys Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Thr Arg His Gly Tyr Asp Ile Leu Thr Gly Tyr Tyr Glu 20 25 30 Thr His Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5627 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5627 Cys Ala Lys Thr Arg Phe Asp Tyr Trp 1 5 <210> 5628 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5628 ttgggccggt tcaccatctc cagagacaat tccaagaaca cgctgtatct gcaaatgaac 60 agcctgagag ccgaggacac ggccgtatat tactgtgcga aaacccgatt tgactactgg 120 ggccaggga 129 <210> 5629 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5629 Leu Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 1 5 10 15 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 20 25 30 Ala Lys Thr Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5630 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5630 aagggccggt tcaccatctc cagagacaat tccaagaaca cgctgtatct gcaaatgaac 60 agcctgagag ccgaggacac ggccgtatat tactgtgcga aaacccgatt tgactactgg 120 ggccaggga 129 <210> 5631 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5631 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 1 5 10 15 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 20 25 30 Ala Lys Thr Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5632 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5632 Cys Ala Lys Gly Gly Asp Tyr Tyr Gly Met Asp Val Trp 1 5 10 <210> 5633 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5633 accatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ggcggtgact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5634 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5634 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly 20 25 30 Asp Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5635 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5635 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa ggcggtgact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5636 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5636 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly 20 25 30 Asp Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5637 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5637 Cys Ala Arg Ile Gln Gly Tyr Ser Tyr Gly Ser Tyr Gly Met Asp Val 1 5 10 15 Trp <210> 5638 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5638 gacacctcca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acgtattact gtgcacggat acaaggatac agctatggtt cgtacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5639 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5639 Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Gln Gly Tyr Ser Tyr 20 25 30 Gly Ser Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5640 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5640 ggacacctcc aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acgtattact gtgcacggat acaaggatac agctatggtt cgtacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5641 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5641 Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Gln Gly Tyr Ser Tyr 20 25 30 Gly Ser Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5642 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5642 Cys Ala Arg Gly Gly Ala Tyr Tyr Asp Ile Leu Thr Gly Tyr Tyr Arg 1 5 10 15 Pro Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 5643 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5643 ttggagctga gcagcctgag atctgaggac acggccgtgt attactgtgc gagagggggg 60 gcgtattacg atattttgac tggttattat aggccctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5644 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5644 Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Gly Ala Tyr Tyr Asp Ile Leu Thr Gly Tyr Tyr Arg Pro 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5645 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5645 atggagctga gcagcctgag atctgaggac acggccgtgt attactgtgc gagagggggg 60 gcgtattacg atattttgac tggttattat aggccctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5646 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5646 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Gly Ala Tyr Tyr Asp Ile Leu Thr Gly Tyr Tyr Arg Pro 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5647 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5647 Cys Ala Arg Glu Gly Gly Leu Gly Arg Leu Asp Pro Trp 1 5 10 <210> 5648 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5648 accatcaacc cagacacatc caagaaccag ttctccctgc agctgaactc tgtgactccc 60 gaggacacgg ctgtatattt ctgtgcaaga gagggggggc tgggccggct cgacccctgg 120 ggccaggga 129 <210> 5649 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5649 Thr Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Glu Gly 20 25 30 Gly Leu Gly Arg Leu Asp Pro Trp Gly Gln Gly 35 40 <210> 5650 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5650 accatcaacc cacacacatc caagaaccag ttctccctgc agctgaactc tgtgactccc 60 gaggacacgg ctgtatattt ctgtgcaaga gagggggggc tgggccggct cgacccctgg 120 ggccaggga 129 <210> 5651 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5651 Thr Ile Asn Pro His Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Glu Gly 20 25 30 Gly Leu Gly Arg Leu Asp Pro Trp Gly Gln Gly 35 40 <210> 5652 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5652 Cys Ala Lys Asp Leu His Arg Ala Ser Tyr Tyr Gly Met Asp Ile Trp 1 5 10 15 <210> 5653 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5653 caccacaacg ccaggacttc cgtgtacctg cagatgaaca gtctgagaac tgacgacacg 60 gccttgtatt tctgtgcaaa agacctccac agggcctctt attatggtat ggatatttgg 120 ggccaaggg 129 <210> 5654 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5654 His His Asn Ala Arg Thr Ser Val Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Thr Asp Asp Thr Ala Leu Tyr Phe Cys Ala Lys Asp Leu His Arg Ala 20 25 30 Ser Tyr Tyr Gly Met Asp Ile Trp Gly Gln Gly 35 40 <210> 5655 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5655 agagacaacg ccaggacttc cgtgtacctg cagatgaaca gtctgagaac tgacgacacg 60 gccttgtatt tctgtgcaaa agacctccac agggcctctt attatggtat ggatatttgg 120 ggccaaggg 129 <210> 5656 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5656 Arg Asp Asn Ala Arg Thr Ser Val Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Thr Asp Asp Thr Ala Leu Tyr Phe Cys Ala Lys Asp Leu His Arg Ala 20 25 30 Ser Tyr Tyr Gly Met Asp Ile Trp Gly Gln Gly 35 40 <210> 5657 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5657 Cys Ala Arg Asp Ser Arg Gly Tyr Gly Phe Asp Tyr Trp 1 5 10 <210> 5658 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5658 accatctcca tacacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gattcgcgtg gttatggttt tgactactgg 120 ggccaggga 129 <210> 5659 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5659 Thr Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ser 20 25 30 Arg Gly Tyr Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5660 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5660 accatctcca gagacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gattcgcgtg gttatggttt tgactactgg 120 ggccaggga 129 <210> 5661 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5661 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ser 20 25 30 Arg Gly Tyr Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5662 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5662 Cys Ala Arg Ala Trp Gly Ser Ile Ala Ala Ala Asp Tyr Trp 1 5 10 <210> 5663 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5663 tttaccgcgg acaaatccac gagcacagcc tacatggagc tgagcagcct gatatctgag 60 gacacggccg tgtattactg tgcgagagct tggggaagta tagcagccgc tgactactgg 120 ggccaggga 129 <210> 5664 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5664 Phe Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Ile Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Trp Gly 20 25 30 Ser Ile Ala Ala Ala Asp Tyr Trp Gly Gln Gly 35 40 <210> 5665 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5665 attaccgcgg acaaatccac gagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagagct tggggaagta tagcagccgc tgactactgg 120 ggccaggga 129 <210> 5666 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5666 Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Trp Gly 20 25 30 Ser Ile Ala Ala Ala Asp Tyr Trp Gly Gln Gly 35 40 <210> 5667 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5667 Cys Ala Arg Ser Arg Met Val Arg Gly Val Ile Met Thr His Phe Asp 1 5 10 15 Ile Trp <210> 5668 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5668 acctccaaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccacg 60 tattactgtg cacggagccg tatggttcgg ggagttatta tgacccattt tgatatctgg 120 ggccaaggg 129 <210> 5669 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5669 Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ser Arg Met Val Arg Gly Val 20 25 30 Ile Met Thr His Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5670 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5670 cacctccaat accaggtggt ccttacaatg accaacatgg accctgtgga cacagccacg 60 tattactgtg cacggagccg tatggttcgg ggagttatta tgacccattt tgatatctgg 120 ggccaaggg 129 <210> 5671 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5671 His Leu Gln Tyr Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ser Arg Met Val Arg Gly Val 20 25 30 Ile Met Thr His Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5672 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5672 Cys Ala Arg Arg Glu Val Gly Ala Gly Leu Asp Tyr Trp 1 5 10 <210> 5673 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5673 accatctcag ccgacaagtc catcagcacc gcctacctgc agtggagcag cctgaaggcc 60 tcggacaccg ccatgtattg ctgtgcgaga cgggaagtgg gagctggatt agactactgg 120 ggccaggga 129 <210> 5674 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5674 Thr Ile Ser Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser 1 5 10 15 Ser Leu Lys Ala Ser Asp Thr Ala Met Tyr Cys Cys Ala Arg Arg Glu 20 25 30 Val Gly Ala Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5675 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5675 accatctcag ccgacaagtc catcagcacc gcctacctgc agtggagcag cctgaaggcc 60 tcggacaccg ccatgtatta ctgtgcgaga cgggaagtgg gagctggatt agactactgg 120 ggccaggga 129 <210> 5676 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5676 Thr Ile Ser Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser 1 5 10 15 Ser Leu Lys Ala Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Arg Glu 20 25 30 Val Gly Ala Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5677 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5677 Cys Ala Arg Ser Gly Ala Thr His Tyr Phe Asp Tyr Trp 1 5 10 <210> 5678 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5678 accatgacca cagacacatc cacgagcaca gcctacatgg agctgaggag cctgagatct 60 gacgacacgg ccgtgtatta ctgtgcgaga tcgggagcta cccactactt tgactactgg 120 ggccaggga 129 <210> 5679 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5679 Thr Met Thr Thr Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg 1 5 10 15 Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ser Gly 20 25 30 Ala Thr His Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5680 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5680 accatgacca cagacacatc cacgagcaca gcctacatgg agctgaggag cctgagacct 60 gacgacacgg ccgtgtatta ctgtgcgaga tcgggagcta cccactactt tgactactgg 120 ggccaggga 129 <210> 5681 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5681 Thr Met Thr Thr Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg 1 5 10 15 Ser Leu Arg Pro Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ser Gly 20 25 30 Ala Thr His Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5682 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5682 Cys Ala Lys Asp Cys Cys Ser Gly Ile Leu Tyr Tyr Gly Met Asp Val 1 5 10 15 Trp <210> 5683 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5683 gacagcgcca agaactccct gtatctgcaa atgaacagtc tgagagctga ggacacggcc 60 ttgtattact gtgcaaaaga ttgctgctcc ggcatcctct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5684 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5684 Asp Ser Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Cys Cys Ser Gly Ile 20 25 30 Leu Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5685 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5685 gacaacgcca agaactccct gtatctgcaa atgaacagtc tgagagctga ggacacggcc 60 ttgtattact gtgcaaaaga ttgctgctcc ggtatcctct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5686 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5686 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Cys Cys Ser Gly Ile 20 25 30 Leu Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5687 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5687 Cys Ala Arg Lys Asn Asn Trp Asn Tyr Asp Leu Pro Asp Ser Trp 1 5 10 15 <210> 5688 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5688 tccttggaca cctctgtcag cacggcatat ctgcagatca gcagcctaaa ggctgagggc 60 actgccgtgt attactgtgc gagaaaaaat aattggaact acgatctccc cgactcctgg 120 ggccaggga 129 <210> 5689 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5689 Ser Leu Asp Thr Ser Val Ser Thr Ala Tyr Leu Gln Ile Ser Ser Leu 1 5 10 15 Lys Ala Glu Gly Thr Ala Val Tyr Tyr Cys Ala Arg Lys Asn Asn Trp 20 25 30 Asn Tyr Asp Leu Pro Asp Ser Trp Gly Gln Gly 35 40 <210> 5690 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5690 tccttggaca cctctgtcag cacggcatat ctgcagatca gcagcctaaa ggctgaggac 60 actgccgtgt attactgtgc gagaaaaaat aactggaact acgatctccc cgactcctgg 120 ggccaggga 129 <210> 5691 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5691 Ser Leu Asp Thr Ser Val Ser Thr Ala Tyr Leu Gln Ile Ser Ser Leu 1 5 10 15 Lys Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Lys Asn Asn Trp 20 25 30 Asn Tyr Asp Leu Pro Asp Ser Trp Gly Gln Gly 35 40 <210> 5692 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5692 Cys Ala Lys Asp Pro Gly Tyr Tyr Tyr Asp Ser Ser Gly Lys Asn Trp 1 5 10 15 Tyr Phe Asp Leu Trp 20 <210> 5693 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5693 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatc ctgggtatta ctatgatagt agtggaaaga actggtactt cgatctctgg 120 ggccgtggc 129 <210> 5694 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5694 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Pro Gly Tyr Tyr Tyr Asp Ser Ser Gly 20 25 30 Lys Asn Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5695 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5695 aacacgatgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatc ctgggtatta ctatgatagt agtggaaaga actggtactt cgatctctgg 120 ggccgtggc 129 <210> 5696 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5696 Asn Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Pro Gly Tyr Tyr Tyr Asp Ser Ser Gly 20 25 30 Lys Asn Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5697 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5697 Cys Ala Arg Ile Arg Ala Ala Ala Gly Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 5698 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5698 ctccaaggac acctccaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acggatacgg gcagcagctg ggtactactt tgactactgg 120 ggccaggga 129 <210> 5699 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5699 Leu Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Arg Ala Ala 20 25 30 Ala Gly Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5700 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5700 tccaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acggatacgg gcagcagctg ggtactactt tgactactgg 120 ggccaggga 129 <210> 5701 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5701 Ser Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Arg Ala Ala 20 25 30 Ala Gly Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5702 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5702 Cys Ala Arg Arg Leu Ile Ser Gly Thr Thr Leu Ala Pro Ser Asp Tyr 1 5 10 15 Trp <210> 5703 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5703 gacacgtcca agaaccagtt ctccctgaag ctgaactctg tgaccgccgc agacacggct 60 gtgtattact gtgcgagacg attgatctca gggactaccc tggcccccag tgactactgg 120 ggccaggga 129 <210> 5704 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5704 Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Asn Ser Val Thr Ala 1 5 10 15 Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Arg Leu Ile Ser Gly Thr 20 25 30 Thr Leu Ala Pro Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 5705 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5705 gacacgccca acaaccagtt ctccctgaag ctgaactctg tgaccgccgc agacacggct 60 gtgtattact gtgcgagacg attgatctca gggactaccc tggcccccag tgactactgg 120 ggccaggga 129 <210> 5706 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5706 Asp Thr Pro Asn Asn Gln Phe Ser Leu Lys Leu Asn Ser Val Thr Ala 1 5 10 15 Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Arg Leu Ile Ser Gly Thr 20 25 30 Thr Leu Ala Pro Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 5707 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5707 Cys Ala Arg Val Gly Ser Gly Asp Ser Ser Gly Tyr Tyr Leu Phe Pro 1 5 10 15 Asp Tyr Trp <210> 5708 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5708 tccatgagca cagtctacat ggagctgagc agcctgagat ctgaggacac ggccgtgtat 60 tactgtgcga gagtagggtc gggtgatagt agtggttatt acttgttccc cgactactgg 120 ggccaggga 129 <210> 5709 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5709 Ser Met Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly Ser Gly Asp Ser Ser Gly 20 25 30 Tyr Tyr Leu Phe Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 5710 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5710 tccacgagca cagtctacat ggagctgagc agcctgagat ctgaggacac ggccgtgtat 60 tactgtgcga gagtagggtc gggtgatagt agtggttatt acttgttccc cgactactgg 120 ggccaggga 129 <210> 5711 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5711 Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly Ser Gly Asp Ser Ser Gly 20 25 30 Tyr Tyr Leu Phe Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 5712 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5712 Cys Ala Arg Pro His Gly Thr Ala Trp Tyr Pro Trp Phe Asp Pro Trp 1 5 10 15 <210> 5713 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5713 gttgacacgt ccaagaacca gttctccctg aagctgaact ctgtgaccgc cgcagacacg 60 gctgtgtatt actgtgcgag accccatggc actgcctggt acccgtggtt cgacccctgg 120 ggccaggga 129 <210> 5714 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5714 Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Asn Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Pro His Gly Thr Ala 20 25 30 Trp Tyr Pro Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5715 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5715 gttgacacgc ccaagaacca gttcaccctg aagctgaact ctgtgaccgc cgcagacacg 60 gctgtgtatt actgtgcgag accccatggc actgcctggt acccgtggtt cgacccctgg 120 ggccaggga 129 <210> 5716 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5716 Val Asp Thr Pro Lys Asn Gln Phe Thr Leu Lys Leu Asn Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Pro His Gly Thr Ala 20 25 30 Trp Tyr Pro Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5717 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5717 Cys Ala Arg Gly Thr Thr Leu Pro Ser Tyr Asp Phe Trp Ser Gly Asn 1 5 10 15 Ser Gly Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 5718 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5718 ttggagctga gcagcctgag atctgaggac acggccgtgt attactgtgc gagagggact 60 acacttccga gttacgattt ttggagtggg aactcaggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5719 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5719 Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Thr Thr Leu Pro Ser Tyr Asp Phe Trp Ser Gly Asn Ser 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5720 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5720 atggagctga gcagcctgag atctgaggac acggccgtgt attactgtgc gagagggact 60 acacttccga gttacgattt ttggagtggg aactcaggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5721 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5721 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Thr Thr Leu Pro Ser Tyr Asp Phe Trp Ser Gly Asn Ser 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5722 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5722 Cys Ala Arg Asp Pro Thr Pro Val Val Val Leu Gln Gly His Ala Phe 1 5 10 15 Asp Ile Trp <210> 5723 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5723 tccacgagca cagcctacat ggagctgagc agcctgagat ctgaggacac ggccgtgtat 60 tactgtgcga gagatccaac tcctgtagtg gttctacagg ggcatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5724 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5724 Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro Thr Pro Val Val Val Leu 20 25 30 Gln Gly His Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5725 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5725 tccacgagca aagcctacat ggagctgagc agcctgagat ctgaggacac ggccgtgtat 60 tactgtgcga gagatccaac tcctgtagtg gttctacagg ggcatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5726 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5726 Ser Thr Ser Lys Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro Thr Pro Val Val Val Leu 20 25 30 Gln Gly His Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5727 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5727 Cys Ala Arg Ala Pro Ala Ala Ala Gly Asp Tyr Tyr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 5728 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5728 acgagcacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgaggg cccccgcagc agctggggat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5729 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5729 Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Ala Pro Ala Ala Ala Gly Asp Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5730 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5730 acgaccaccg cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgaggg cccccgcagc agctggggat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5731 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5731 Thr Thr Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Ala Pro Ala Ala Ala Gly Asp Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5732 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5732 Cys Ala Lys Val Ile Thr Ile Gly Pro Asp Tyr Trp 1 5 10 <210> 5733 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5733 ttcaccatct ccagagacaa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagttatta cgataggacc tgactactgg 120 ggccaggga 129 <210> 5734 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5734 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val 20 25 30 Ile Thr Ile Gly Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 5735 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5735 ttcaccatct ccagacacaa ttccaagaac acgctgtatc tgcaaatcaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagttatta cgataggacc tgactactgg 120 ggccaggga 129 <210> 5736 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5736 Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val 20 25 30 Ile Thr Ile Gly Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 5737 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5737 Cys Ala Arg Thr Asp Trp Phe Asp Pro Trp 1 5 10 <210> 5738 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5738 ggcagagtca ccatgaccag gaacacctcc ataagcacag cctacatgga gctgagcagc 60 ctgagatctg aggacacggc cgtgtattac tgtgcgagga cggactggtt cgacccctgg 120 ggccaggga 129 <210> 5739 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5739 Gly Arg Val Thr Met Thr Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met 1 5 10 15 Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Arg Thr Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5740 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5740 ggcagagaca ccatgaccag caacacctcc ataagcacag cctacatgga gctgagcagc 60 ctgagatctg aggacacggc cgtgtattac tgtgcgagga cggactggtt cgacccctgg 120 ggccaggga 129 <210> 5741 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5741 Gly Arg Asp Thr Met Thr Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met 1 5 10 15 Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Arg Thr Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5742 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5742 Cys Ala Thr Gly Gly Val Phe Pro Val Gly Trp Leu Asp Pro Trp 1 5 10 15 <210> 5743 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5743 tccagagaca attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaccgggggg gttttcccgg tcggctggct cgacccctgg 120 ggccaggga 129 <210> 5744 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5744 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Gly Gly Val Phe 20 25 30 Pro Val Gly Trp Leu Asp Pro Trp Gly Gln Gly 35 40 <210> 5745 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5745 tacagagaaa attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaccgggggg gttttcccgg tcggctggct cgacccctgg 120 ggccaggga 129 <210> 5746 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5746 Tyr Arg Glu Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Gly Gly Val Phe 20 25 30 Pro Val Gly Trp Leu Asp Pro Trp Gly Gln Gly 35 40 <210> 5747 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5747 Cys Ala Arg Gly Arg Leu Gly Arg Ala Ala Ala Gly Lys Gly Arg Ala 1 5 10 15 Tyr Tyr Phe Asp Tyr Trp 20 <210> 5748 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5748 ctgttctccc tgatgctgag ctctgtgacc gccgcggaca cggctgtgta ttactgtgcg 60 agaggccggt tggggcgggc agcagctggt aagggccgcg cctactactt tgactactgg 120 ggccaggga 129 <210> 5749 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5749 Leu Phe Ser Leu Met Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Arg Leu Gly Arg Ala Ala Ala Gly Lys Gly 20 25 30 Arg Ala Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5750 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5750 cagttctccc tgaagctgag ctctgtgacc gccgcggaca cggctgtgta ttactgtgcg 60 agaggccggt tggggcgggc agcagctggt aagggccgcg cctactactt tgactactgg 120 ggccaggga 129 <210> 5751 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5751 Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Arg Leu Gly Arg Ala Ala Ala Gly Lys Gly 20 25 30 Arg Ala Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5752 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5752 Cys Ala Lys Glu Glu Gly Pro Trp 1 5 <210> 5753 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5753 gtgaagggcc tattcaccat ctccagagac aacgccaaga actccctgta tcttcaaatg 60 aacagtctga gagctgagga cacggccttg tattactgtg caaaagaaga gggcccctgg 120 ggccaggga 129 <210> 5754 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5754 Val Lys Gly Leu Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu 1 5 10 15 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr 20 25 30 Cys Ala Lys Glu Glu Gly Pro Trp Gly Gln Gly 35 40 <210> 5755 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5755 gtgaagggcc gattcaccat ctccagagac aacgccaaga actccctgta tctgcaaatg 60 aacagtctga gagctgagga cacggccttg tattactgtg caaaagaaga gggcccctgg 120 ggccaggga 129 <210> 5756 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5756 Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu 1 5 10 15 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr 20 25 30 Cys Ala Lys Glu Glu Gly Pro Trp Gly Gln Gly 35 40 <210> 5757 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5757 Cys Ala Arg Gln Asp Ala Gly Ala Ser Cys Ile Asp Trp 1 5 10 <210> 5758 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5758 accatctcag ccgacaagtc catcaccacc gcctacctac agttgaacag cctggaggcc 60 tcggacaccg ccatctatta ctgtgcgaga caggatgctg gtgctagttg catcgactgg 120 ggccaggga 129 <210> 5759 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5759 Thr Ile Ser Ala Asp Lys Ser Ile Thr Thr Ala Tyr Leu Gln Leu Asn 1 5 10 15 Ser Leu Glu Ala Ser Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Gln Asp 20 25 30 Ala Gly Ala Ser Cys Ile Asp Trp Gly Gln Gly 35 40 <210> 5760 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5760 ccatctcagc cgacaagtcc atccaccacc gcctacctac agttgaacag cctggaggcc 60 tcggacaccg ccatctatta ctgtgcgaga caggatgctg gtgctagttg catcgactgg 120 ggccaggga 129 <210> 5761 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5761 Pro Ser Gln Pro Thr Ser Pro Ser Thr Thr Ala Tyr Leu Gln Leu Asn 1 5 10 15 Ser Leu Glu Ala Ser Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Gln Asp 20 25 30 Ala Gly Ala Ser Cys Ile Asp Trp Gly Gln Gly 35 40 <210> 5762 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5762 Cys Thr Thr Asp Pro Tyr Asp Phe Trp Thr Asp Tyr Trp 1 5 10 <210> 5763 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5763 accatctcaa gagatgattc aaaaaacacg ctgtatctgc aaatgaacag cctgaaaacc 60 gaggacacag ccgtgtatta ctgtaccaca gacccatacg atttttggac tgactactgg 120 ggccaggga 129 <210> 5764 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5764 Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Asp Pro 20 25 30 Tyr Asp Phe Trp Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 5765 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5765 accatctcaa gagatgattc aaaaaacacg ctgtatctgc aaatgaacag cctgaaaacc 60 gaggacacag ccgtgcatta ctgtaccaca gacccatacg atttttggac tgactactgg 120 ggccaggga 129 <210> 5766 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5766 Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val His Tyr Cys Thr Thr Asp Pro 20 25 30 Tyr Asp Phe Trp Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 5767 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5767 Cys Ala His Ser Tyr Pro Phe Met Thr Thr Val Thr Tyr Phe Asp Tyr 1 5 10 15 Trp <210> 5768 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5768 gacacctcca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacag ttaccccttt atgactacgg tgacctactt tgactactgg 120 ggccaggga 129 <210> 5769 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5769 Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Tyr Pro Phe Met Thr 20 25 30 Thr Val Thr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5770 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5770 ggacacctcc aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacag ttaccccttt atgactacgg tgacctactt tgactactgg 120 ggccaggga 129 <210> 5771 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5771 Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Tyr Pro Phe Met Thr 20 25 30 Thr Val Thr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5772 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5772 Cys Ile Pro Gly Tyr Ser Ser Gly Leu Arg Leu Leu Asp Tyr Trp 1 5 10 15 <210> 5773 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5773 tccagagatt attcaaacaa cacggcgtat ctgcaaatga acagcctgaa aaccgaggac 60 acggccgtgt attactgtat tcccgggtat agcagtggcc tgaggctact tgactactgg 120 ggccaggga 129 <210> 5774 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5774 Ser Arg Asp Tyr Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ile Pro Gly Tyr Ser Ser 20 25 30 Gly Leu Arg Leu Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5775 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5775 tccagagatg attcaaagaa cacggcgtat ctgcaaatga acagcctgaa aaccgaggac 60 acggccgtgt attactgtat tcccgggtat agcagtggcc tgaggctact tgactactgg 120 ggccaggga 129 <210> 5776 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5776 Ser Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ile Pro Gly Tyr Ser Ser 20 25 30 Gly Leu Arg Leu Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5777 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5777 Cys Ala Arg Asn Leu Leu Phe Ala Asp Phe Trp 1 5 10 <210> 5778 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5778 ttaatcaccc tgaccatgga cacgtccacg agcacagtct acatggaact gagcagcctg 60 agatctgagg acacggccgt gtattactgt gcgagaaacc ttctttttgc ggacttctgg 120 ggccaggga 129 <210> 5779 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5779 Leu Ile Thr Leu Thr Met Asp Thr Ser Thr Ser Thr Val Tyr Met Glu 1 5 10 15 Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Asn Leu Leu Phe Ala Asp Phe Trp Gly Gln Gly 35 40 <210> 5780 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5780 agaatcaccc tgaccatgga cacgtccacg agcacagtct acatggaact gagcagcctg 60 agatctgagg acacggccgt gtattactgt gcgagaaacc ttctttttgc ggacttctgg 120 ggccaggga 129 <210> 5781 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5781 Arg Ile Thr Leu Thr Met Asp Thr Ser Thr Ser Thr Val Tyr Met Glu 1 5 10 15 Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Asn Leu Leu Phe Ala Asp Phe Trp Gly Gln Gly 35 40 <210> 5782 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5782 Cys Ala Ser Tyr Ser Asn Ser Trp Ser Ser Trp Asp Tyr Trp 1 5 10 <210> 5783 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5783 atatcagtag acacgtccaa aaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggccg tgtattactg tgccagttat agtaacagct ggtcgagttg ggactactgg 120 ggccaggga 129 <210> 5784 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5784 Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Ser Tyr Ser Asn 20 25 30 Ser Trp Ser Ser Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 5785 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5785 acatcagtag acacgtccaa aaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggccg tgtattactg tgccagttat agtaacagct ggtcgagttg ggactactgg 120 ggccaggga 129 <210> 5786 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5786 Thr Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Ser Tyr Ser Asn 20 25 30 Ser Trp Ser Ser Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 5787 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5787 Cys Ala Lys Phe Ile Ala Ala Ala Gly Phe Asp Tyr Trp 1 5 10 <210> 5788 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5788 accatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa tttatagcag cagctggttt tgactactgg 120 ggccaggga 129 <210> 5789 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5789 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Phe Ile 20 25 30 Ala Ala Ala Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5790 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5790 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa tttatagcag cagctggttt tgactactgg 120 ggccaggga 129 <210> 5791 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5791 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Phe Ile 20 25 30 Ala Ala Ala Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5792 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5792 Cys Ala Arg Ala Leu Arg Ser Gly Gln Gly Ser Ser Pro Ser Asn Asn 1 5 10 15 Trp Phe Asp Pro Trp 20 <210> 5793 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5793 aaccagttct ccctgaagct gagctctgtg accgccgcgg acacggctgt gtattactgt 60 gcgagagccc tgcgatcagg ccagggcagc agcccctcga acaactggtt cgacccctgg 120 ggccaggga 129 <210> 5794 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5794 Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Ala Leu Arg Ser Gly Gln Gly Ser Ser Pro 20 25 30 Ser Asn Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5795 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5795 aaccagttct ccccgaagct gagctctgtg accgccgcgg acacggctgt gtattactgt 60 gcgagagccc tgcgatcagg ccagggcagc agcccctcga acaactggtt cgacccctgg 120 ggccaggga 129 <210> 5796 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5796 Asn Gln Phe Ser Pro Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Ala Leu Arg Ser Gly Gln Gly Ser Ser Pro 20 25 30 Ser Asn Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5797 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5797 Cys Ala Lys Gly Pro Ile Val Val Val Pro Ala Ala Ile Arg Asn Pro 1 5 10 15 Pro Asp Tyr Trp 20 <210> 5798 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5798 aagaacacgc tgtatctgca aatgaacagc ctgagagccg aggacacggc cgtatattac 60 tgtgccaagg ggccgattgt agtagtacca gctgctatac gtaatccccc agactactgg 120 ggccaggga 129 <210> 5799 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5799 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Gly Pro Ile Val Val Val Pro Ala Ala 20 25 30 Ile Arg Asn Pro Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 5800 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5800 aagaacacgc tgtatctaca aatgaacagc ctgagagccg aggacacggc cgtatattac 60 tgtgccaagg ggccgattgt agtagtacca gctgctatac gtaatccccc agactactgg 120 ggccaggga 129 <210> 5801 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5801 Cys Ala Arg Arg Gly Ser Ser Trp Ser Trp Ala Phe Asp Pro Trp 1 5 10 15 <210> 5802 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5802 tcagccgaca gctccagcag caccgcctac ctgcagtgga gcagcctgaa ggcctcggac 60 accgccatgt attactgtgc gagacgtggc agcagctggt catgggcctt cgacccctgg 120 ggccaggga 129 <210> 5803 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5803 Ser Ala Asp Ser Ser Ser Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu 1 5 10 15 Lys Ala Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Arg Gly Ser Ser 20 25 30 Trp Ser Trp Ala Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5804 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5804 tcagccgaca agtccatcag caccgcctac ctgcagtgga gcagcctgaa ggcctcggac 60 accgccatgt attactgtgc gagacgtggc agcagctggt catgggcctt cgacccctgg 120 ggccaggga 129 <210> 5805 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5805 Ser Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu 1 5 10 15 Lys Ala Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Arg Gly Ser Ser 20 25 30 Trp Ser Trp Ala Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5806 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5806 Cys Ala Arg Asp Ile Asp Ala Pro Gly Thr Thr Tyr Tyr Phe Asp Tyr 1 5 10 15 Trp <210> 5807 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5807 gacaacgcca agaactccct gtatctgcaa atggactccc tgagagccga ggacacggcc 60 gtgtactact gtgcgagaga tatagacgcg cctggaacga cctattactt tgactactgg 120 ggccaggga 129 <210> 5808 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5808 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asp Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ile Asp Ala Pro Gly 20 25 30 Thr Thr Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5809 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5809 gacaacgcca acaactccct gtatctgcaa atggactccc tgagagccga ggacacggcc 60 gtgtactact gtgcgagaga tatagacgcg cctggaacga cctattactt tgactactgg 120 ggccaggga 129 <210> 5810 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5810 Asp Asn Ala Asn Asn Ser Leu Tyr Leu Gln Met Asp Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ile Asp Ala Pro Gly 20 25 30 Thr Thr Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5811 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5811 Cys Ala Arg Val Arg Pro Val Val Ala Thr Met Phe Leu Asn Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 5812 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5812 tgcacagtct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagttc ggccggtagt ggctacgatg ttcctaaact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5813 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5813 Cys Thr Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Val Arg Pro Val Val Ala Thr Met Phe Leu 20 25 30 Asn Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5814 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5814 agcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagttc ggccggtagt ggctacgatg ttcctaaact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5815 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5815 Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Val Arg Pro Val Val Ala Thr Met Phe Leu 20 25 30 Asn Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5816 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5816 Cys Ala Arg Leu Ser Thr Gln Gln Trp Leu Pro Glu Asp Ala Phe Asp 1 5 10 15 Met Trp <210> 5817 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5817 aaatccatct gtaccgccta cttgcagcgg agtagtctgc aggtctcgga caccgccata 60 tattactgtg cgagactgtc gactcagcag tggctgccag aagatgcttt tgatatgtgg 120 ggccaaggg 129 <210> 5818 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5818 Lys Ser Ile Cys Thr Ala Tyr Leu Gln Arg Ser Ser Leu Gln Val Ser 1 5 10 15 Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Leu Ser Thr Gln Gln Trp Leu 20 25 30 Pro Glu Asp Ala Phe Asp Met Trp Gly Gln Gly 35 40 <210> 5819 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5819 aaatccatca gtaccgccta catgcagcgg agtagtctgc aggtctcgga caccgccata 60 tattactgtg cgagactgtc gactcagcag tggctgccag aagatgcttt tgatatgtgg 120 ggccaaggg 129 <210> 5820 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5820 Lys Ser Ile Ser Thr Ala Tyr Met Gln Arg Ser Ser Leu Gln Val Ser 1 5 10 15 Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Leu Ser Thr Gln Gln Trp Leu 20 25 30 Pro Glu Asp Ala Phe Asp Met Trp Gly Gln Gly 35 40 <210> 5821 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5821 Cys Thr Thr Asp Leu Tyr Arg Tyr Ser Ser Ser Trp Asp Tyr Phe Asp 1 5 10 15 Tyr Trp <210> 5822 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5822 gattcaaaaa acacgctgta tctgcaaatg aacagcctga aaaccgagga cacagccgtg 60 tattattgta ccacagatct atataggtat agcagcagct gggactactt tgactactgg 120 ggccaggga 129 <210> 5823 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5823 Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Thr Thr Asp Leu Tyr Arg Tyr Ser Ser 20 25 30 Ser Trp Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5824 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5824 gattcaaaaa acacgctgta tctgcaaatg aacagcctga aaaccgagga cacagccgtg 60 tattactgta ccacagatct atataggtat agcagcagct gggactactt tgactactgg 120 ggccaggga 129 <210> 5825 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5825 Cys Thr Arg Gln Leu Gly Gly Ser Gly Ser Asp Tyr Trp 1 5 10 <210> 5826 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5826 atcatcagcc cagacacatc caagaaccag ttctccctgc aattgaactc tgtgactccc 60 gacgacacgg ctgtgtatta ctgtacaaga cagctcggtg gttcaggatc tgattactgg 120 ggccaggga 129 <210> 5827 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5827 Ile Ile Ser Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Asp Asp Thr Ala Val Tyr Tyr Cys Thr Arg Gln Leu 20 25 30 Gly Gly Ser Gly Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 5828 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5828 atcatcaacc cagacacatc caagaaccag ttctccctgc aactgaactc tgtgactccc 60 gaggacacgg ctgtgtatta ctgtacaaga caactcggtg gttcaggatc tgattactgg 120 ggccaggga 129 <210> 5829 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5829 Ile Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Gln Leu 20 25 30 Gly Gly Ser Gly Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 5830 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5830 Cys Ala Arg Gly Gln Glu Glu Gly Tyr Ser Ser Ser Trp Tyr Arg Gly 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 5831 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5831 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagaggccag 60 gaggaggggt atagcagcag ctggtaccgg ggctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5832 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5832 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Gln Glu Glu Gly Tyr Ser Ser Ser Trp Tyr Arg Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5833 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5833 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagaggccag 60 gaggaggggt atagcagcag ctggtaccgg ggctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5834 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5834 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Gln Glu Glu Gly Tyr Ser Ser Ser Trp Tyr Arg Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5835 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5835 Cys Ala His Ser Leu Ser Pro Tyr Ser Pro Ala Trp Phe Asp Pro Trp 1 5 10 15 <210> 5836 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5836 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagtctgagt ccttatagcc ccgcctggtt cgacccctgg 120 ggccaggga 129 <210> 5837 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5837 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Leu Ser Pro Tyr 20 25 30 Ser Pro Ala Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5838 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5838 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagtctgagt ccttatagcc ccgcctggtt cgacccctgg 120 ggccaggga 129 <210> 5839 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5839 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Leu Ser Pro Tyr 20 25 30 Ser Pro Ala Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5840 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5840 Cys Ala Lys Gly Arg Ser Ser Trp Pro Tyr Tyr Tyr Tyr Gly Met Asp 1 5 10 15 Val Trp <210> 5841 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5841 aattccaaga acacgctgta tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgaaggggcg cagcagctgg ccctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5842 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5842 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Arg Ser Ser Trp Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5843 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5843 aattccaaga acacgctgta tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgaaagggcg cagcagctgg ccctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5844 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5844 Cys Ala Lys Asp Leu Gly Ser Gly Ser Ser Ala Tyr Tyr Tyr Gly Met 1 5 10 15 Asp Val Trp <210> 5845 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5845 gccaagaact ccctgtatct gcaaatgaac agtctgagag ctgaggacac ggccttgtat 60 tactgtgcaa aagatcttgg ttcggggagc tcagcgtact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5846 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5846 Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Leu Gly Ser Gly Ser Ser Ala 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5847 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5847 gccaagaact ccctgtatct gcaaatgaac agcctgagag ctgaggacac ggccttgtat 60 tactgtgcaa aagatcttgg ttcggggagc tcagcgtact actacggtat ggacgtctgg 120 ggccaagga 129 <210> 5848 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5848 Cys Ala Arg Gly Ala Pro Asp Ser Ser Gly Tyr Tyr Phe Gln Gly Glu 1 5 10 15 Val Tyr Phe Asp Tyr Trp 20 <210> 5849 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5849 tcgctgtatc ttctaatggg cagcctgaga gctgaggaca tggctgtgta ttactgtgcg 60 agaggggccc ctgatagtag tggttattac ttccaagggg aggtctactt tgactactgg 120 ggccaggga 129 <210> 5850 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5850 Ser Leu Tyr Leu Leu Met Gly Ser Leu Arg Ala Glu Asp Met Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Ala Pro Asp Ser Ser Gly Tyr Tyr Phe Gln 20 25 30 Gly Glu Val Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5851 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5851 acgctgtatc ttcaaatggg cagcctgaga gctgaggaca tggctgtgta ttactgtgcg 60 agaggggccc ctgatagtag tggttattac ttccaagggg aggtctactt tgactactgg 120 ggccaggga 129 <210> 5852 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5852 Thr Leu Tyr Leu Gln Met Gly Ser Leu Arg Ala Glu Asp Met Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Ala Pro Asp Ser Ser Gly Tyr Tyr Phe Gln 20 25 30 Gly Glu Val Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5853 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5853 Cys Ala Ile Leu Ala Arg Thr Ser Tyr Phe Asp Trp Ser Lys Ile Phe 1 5 10 15 Asp Tyr Trp <210> 5854 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5854 tccatcagca cagcctacat ggagctgagc aggctgagat ctgacgacac ggccgtgtat 60 tactgtgcga tcctagcccg gacctcctat tttgactggt caaaaatctt tgactactgg 120 ggccgggga 129 <210> 5855 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5855 Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg Ser Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Ile Leu Ala Arg Thr Ser Tyr Phe Asp 20 25 30 Trp Ser Lys Ile Phe Asp Tyr Trp Gly Arg Gly 35 40 <210> 5856 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5856 tccatcagca cagcctacat ggagctgagc aggctgagat ctgacgacac ggccgtgtat 60 tactgtgcga tcctagcccg gacctcctat tttgactggt caaaaatctt tgactactgg 120 ggccaggga 129 <210> 5857 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5857 Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg Ser Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Ile Leu Ala Arg Thr Ser Tyr Phe Asp 20 25 30 Trp Ser Lys Ile Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5858 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5858 Cys Ala Arg Leu Val Val Ser Ala Ala Gly Asn Ser His Phe Asp Tyr 1 5 10 15 Trp <210> 5859 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5859 gacaagtcca tcagcaccgc ctacctgcag tggagcagcc tgaaggcctc ggacaccgcc 60 atgtattact gtgcgagact tgtggttagt gcagctggca actctcactt tgactactgg 120 ggccaggga 129 <210> 5860 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5860 Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala 1 5 10 15 Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Leu Val Val Ser Ala Ala 20 25 30 Gly Asn Ser His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5861 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5861 gacaagtcca tcagcaccgc ctacctgcag tggagcagcc tgaaggcctc ggacaccgcc 60 atgtattact gtgcgagact tgtggttagt gcagctggca actcccactt tgactactgg 120 ggccgggga 129 <210> 5862 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5862 Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala 1 5 10 15 Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Leu Val Val Ser Ala Ala 20 25 30 Gly Asn Ser His Phe Asp Tyr Trp Gly Arg Gly 35 40 <210> 5863 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5863 Cys Ala Arg Glu Pro Pro Pro Thr Met Thr Thr Val Val Thr Ile Leu 1 5 10 15 Asp Tyr Trp <210> 5864 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5864 tccacgagca cagtctacat ggagctgagc agcctgagat ctgaggacac ggccgtgtat 60 tactgtgcga gggaaccccc ccccaccatg actacggtgg taacgattct ggactactgg 120 ggccaggga 129 <210> 5865 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5865 Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Pro Pro Thr Met Thr Thr 20 25 30 Val Val Thr Ile Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5866 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5866 gacacgagca cagtctacat ggagctgagc agcctgagat ctgaggacac ggccgtgtat 60 tactgtgcga gggaaccccc ccccaccatg actacggtgg taacgattct ggactactgg 120 ggccaggga 129 <210> 5867 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5867 Asp Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Pro Pro Thr Met Thr Thr 20 25 30 Val Val Thr Ile Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5868 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5868 Cys Ala Lys Asp Leu Pro Tyr Cys Gly Gly Asp Cys Tyr Pro Asp Ala 1 5 10 15 Phe Asp Ile Trp 20 <210> 5869 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5869 aagaacgcgc tgtttctgca aatgaacagc ctgagagccg aggacacggc tgtgtattac 60 tgtgcgaaag accttccata ttgtggtggt gactgctacc ctgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5870 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5870 Lys Asn Ala Leu Phe Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Asp Leu Pro Tyr Cys Gly Gly Asp Cys 20 25 30 Tyr Pro Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5871 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5871 aagaacacgc tgtttctgca aatgaacagc ctgagagccg aggacacggc tgtgtattac 60 tgtgcgaaag accttccata ttgtggtggt gactgctacc ctgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5872 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5872 Lys Asn Thr Leu Phe Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Asp Leu Pro Tyr Cys Gly Gly Asp Cys 20 25 30 Tyr Pro Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5873 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5873 Cys Ala His Ser Ala Leu Tyr Tyr Gly Ser Gly Pro Arg Gly Trp Phe 1 5 10 15 Asp Pro Trp <210> 5874 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5874 tccaaaaacc gggtggtcct tacaatgacc aacatggacc ctgtggacac agccacatat 60 tactgtgcac acagcgctct ttactatggt tcagggcccc ggggatggtt cgacccctgg 120 ggccaggga 129 <210> 5875 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5875 Ser Lys Asn Arg Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala His Ser Ala Leu Tyr Tyr Gly Ser Gly 20 25 30 Pro Arg Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5876 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5876 tccaaaaacc aggtggtcct tacaatgacc aacatggacc ctgtggacac agccacatat 60 tactgtgcac acagcgctct ttactatggt tcagggcccc ggggatggtt cgacccctgg 120 ggccaggga 129 <210> 5877 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5877 Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala His Ser Ala Leu Tyr Tyr Gly Ser Gly 20 25 30 Pro Arg Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5878 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5878 Cys Ala Ser Trp Gly Pro Leu Trp Ser Gly Ser Pro Asn Asp Ala Phe 1 5 10 15 Asp Ile Trp <210> 5879 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5879 gccaagaact cgatgtatct gcaaatgaac agtctgagag ccgaggacac ggctgtgtat 60 tactgtgcaa gctgggggcc cctttggagt ggttccccaa atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5880 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5880 Ala Lys Asn Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Ser Trp Gly Pro Leu Trp Ser Gly Ser 20 25 30 Pro Asn Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5881 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5881 gccaagaaca cgctgtatct gcaaatgaac agtctgagag ccgaggacac ggctgtgtat 60 tactgtgcaa gctgggggcc cctttggagt ggttccccaa atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5882 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5882 Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Ser Trp Gly Pro Leu Trp Ser Gly Ser 20 25 30 Pro Asn Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5883 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5883 Cys Ala Lys Pro Pro Gly Gly Tyr Ser Ser Ser Trp Tyr Tyr Leu Asp 1 5 10 15 Tyr Trp <210> 5884 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5884 aactccatga acaccctgta cctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgaaaccgcc gggggggtat agcagcagct ggtactacct tgactattgg 120 ggccaggga 129 <210> 5885 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5885 Asn Ser Met Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro Pro Gly Gly Tyr Ser Ser 20 25 30 Ser Trp Tyr Tyr Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5886 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5886 aactccatca acaccctgta cctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgaaaccgcc gggggggtat agcagcagct ggtactacct tgactattgg 120 ggccaggga 129 <210> 5887 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5887 Asn Ser Ile Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro Pro Gly Gly Tyr Ser Ser 20 25 30 Ser Trp Tyr Tyr Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5888 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5888 Cys Ala Arg Gly Leu Gly Gly Ser Pro Gly Leu Asp Tyr Trp 1 5 10 <210> 5889 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5889 ttgaccaggg acacgtccac gagcacagtc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgaggggg ctcgggggga gccccgggct tgactactgg 120 ggccaggga 129 <210> 5890 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5890 Leu Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Leu Gly 20 25 30 Gly Ser Pro Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5891 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5891 atgaccaggg acacgtccac gagcacagtc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgaggggg ctcgggggga gccccgggct tgactactgg 120 ggccaggga 129 <210> 5892 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5892 Met Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Leu Gly 20 25 30 Gly Ser Pro Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 5893 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5893 Cys Ala Lys Ala Val Val Gln Gly Val Tyr Trp 1 5 10 <210> 5894 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5894 cggttcacca tctccagaga caattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaggcgg tggtacaagg agtatactgg 120 ggccaggga 129 <210> 5895 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5895 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Ala Val Val Gln Gly Val Tyr Trp Gly Gln Gly 35 40 <210> 5896 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5896 cggttcacca tctccagaca caattccaag aacacgctgt atctgcaaat caacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaggcgg tggtacaagg agtatactgg 120 ggccaggga 129 <210> 5897 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5897 Arg Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Ala Val Val Gln Gly Val Tyr Trp Gly Gln Gly 35 40 <210> 5898 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5898 Cys Ala Arg Glu Gln Ser Leu Arg Asn Pro Asn Tyr Tyr Tyr Phe Tyr 1 5 10 15 Ala Met Asp Val Trp 20 <210> 5899 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5899 tgcacagcct acttggagct gagcagcctg agatctgaag acacggctgt gtattactgt 60 gcgagagagc aaagtctaag gaacccaaat tactactact tctacgctat ggacgtctgg 120 ggccaaggg 129 <210> 5900 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5900 Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Gln Ser Leu Arg Asn Pro Asn Tyr Tyr 20 25 30 Tyr Phe Tyr Ala Met Asp Val Trp Gly Gln Gly 35 40 <210> 5901 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5901 agcacagcct acatggagct gagcagcctg agatctgaag acacggctgt gtattactgt 60 gcgagagagc aaagtctaag gaacccaaat tactactact tctacgctat ggacgtctgg 120 ggccaaggg 129 <210> 5902 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5902 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Gln Ser Leu Arg Asn Pro Asn Tyr Tyr 20 25 30 Tyr Phe Tyr Ala Met Asp Val Trp Gly Gln Gly 35 40 <210> 5903 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5903 Cys Ala Arg Val Arg Gln Gly Leu Arg Arg Thr Trp Tyr Tyr Phe Asp 1 5 10 15 Tyr Trp <210> 5904 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5904 aattccaaga acacgctgta tctgcaaatg aacagtctga gagccgagga cacggctgtg 60 tattactgtg caagagtgag gcaaggacta cggaggacgt ggtactactt tgactactgg 120 ggccaggga 129 <210> 5905 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5905 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Arg Gln Gly Leu Arg Arg 20 25 30 Thr Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5906 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5906 aacgccaaga acacgctgta tctgcaaatg aacagtctga gagccgagga cacggctgtg 60 tattactgtg caagagtgag gcaaggacta cggaggacgt ggtactactt tgactactgg 120 ggccaggga 129 <210> 5907 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5907 Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Arg Gln Gly Leu Arg Arg 20 25 30 Thr Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5908 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5908 Cys Ala His Gly Arg Gly Ser Tyr Tyr Tyr Asp Ser Asn Tyr Phe Asp 1 5 10 15 Tyr Trp <210> 5909 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5909 acctccaaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacgggcg gggatcatat tactatgata gtaactactt tgactactgg 120 ggccaggga 129 <210> 5910 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5910 Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Arg Gly Ser Tyr Tyr Tyr 20 25 30 Asp Ser Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5911 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5911 cacctccaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacgggcg gggatcatat tactatgata gtaactactt tgactactgg 120 ggccaggga 129 <210> 5912 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5912 His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Arg Gly Ser Tyr Tyr Tyr 20 25 30 Asp Ser Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5913 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5913 Cys Ala His Arg Ser Ser Gly Tyr Ser Tyr Gly Ser Asp Tyr Phe Asp 1 5 10 15 Tyr Trp <210> 5914 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5914 acctccaaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacaggag cagtggatac agctatggtt cagactactt tgactactgg 120 ggccaggga 129 <210> 5915 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5915 Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Ser Ser Gly Tyr Ser Tyr 20 25 30 Gly Ser Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5916 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5916 cacctccaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacaggag cagtggatac agctatggtt cagactactt tgactactgg 120 ggccaggga 129 <210> 5917 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5917 His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Ser Ser Gly Tyr Ser Tyr 20 25 30 Gly Ser Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5918 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5918 Cys Ala Lys Asp Met Arg Tyr Cys Ser Ser Pro Gly Cys Tyr Gly Asp 1 5 10 15 Trp Tyr Phe Asp Leu Trp 20 <210> 5919 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5919 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagatatga gatattgtag tagtcccggc tgctatggcg actggtactt cgatctctgg 120 ggccgtggc 129 <210> 5920 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5920 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Met Arg Tyr Cys Ser Ser Pro Gly Cys Tyr 20 25 30 Gly Asp Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5921 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5921 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagatatga gatattgtag tagtcccggc tgctatggcg actggtactt cgatctctgg 120 ggccgtggc 129 <210> 5922 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5922 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Met Arg Tyr Cys Ser Ser Pro Gly Cys Tyr 20 25 30 Gly Asp Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 5923 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5923 Cys Ala Arg Asp Leu Arg Ile Pro Ala Gly Thr Glu Gly Phe Asp Tyr 1 5 10 15 Trp <210> 5924 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5924 gacaattcca aggacacact gtatcttcaa atgaacagcc tgagagccga ggacatggcc 60 gtgtatttct gtgcgagaga tctccgtata ccagctggta ccgagggctt tgactactgg 120 ggccaggga 129 <210> 5925 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5925 Asp Asn Ser Lys Asp Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Met Ala Val Tyr Phe Cys Ala Arg Asp Leu Arg Ile Pro Ala 20 25 30 Gly Thr Glu Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5926 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5926 gacaattcca agaacacact gtatcttcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtatttct gtgcgagaga tctccgtata ccagctggta ccgagggctt tgactactgg 120 ggccaggga 129 <210> 5927 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5927 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Asp Leu Arg Ile Pro Ala 20 25 30 Gly Thr Glu Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5928 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5928 Cys Ser Arg Arg Met Gly Ser Tyr Ser Gly His Tyr Leu Gly Tyr Trp 1 5 10 15 <210> 5929 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5929 agtaacacat ccataagtac agcctacatg gaattgagcg gcctgaaatc tgacgacacg 60 gccgtctact attgttcgag gaggatgggc tcttatagtg gacactactt aggctactgg 120 ggccaggga 129 <210> 5930 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5930 Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Gly Leu Lys 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ser Arg Arg Met Gly Ser Tyr 20 25 30 Ser Gly His Tyr Leu Gly Tyr Trp Gly Gln Gly 35 40 <210> 5931 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5931 aggaacacat ccataagtac agcctacatg gaattgagcg gcctgaaatc tgacgacacg 60 gccgtctact attgttcgag gaggatgggc tcttatagtg gacactactt aggctactgg 120 ggccaggga 129 <210> 5932 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5932 Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Gly Leu Lys 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ser Arg Arg Met Gly Ser Tyr 20 25 30 Ser Gly His Tyr Leu Gly Tyr Trp Gly Gln Gly 35 40 <210> 5933 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5933 Cys Ala Arg Val Gly Glu Thr Ala Ala Ala Gly Met Val Asp Tyr Trp 1 5 10 15 <210> 5934 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5934 tgggacaacg ccaagaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgag agtgggggaa acagcagcag ctggaatggt ggactactgg 120 ggccaggga 129 <210> 5935 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5935 Trp Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly Glu Thr Ala 20 25 30 Ala Ala Gly Met Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 5936 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5936 agggacaacg ccaagaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgag agtgggggaa acagcagcag ctggaatggt ggactactgg 120 ggccaggga 129 <210> 5937 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5937 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly Glu Thr Ala 20 25 30 Ala Ala Gly Met Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 5938 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5938 Cys Ala Lys Val Phe Ser Asn Ser His Phe Phe Asp Tyr Trp 1 5 10 <210> 5939 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5939 atctccatac acaattccaa gagcacgctg tatctgcaaa tgaacagcct gagacccgag 60 gacacggccg tatattactg tgcgaaagtg tttagcaaca gccacttctt tgactactgg 120 ggccaggga 129 <210> 5940 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5940 Ile Ser Ile His Asn Ser Lys Ser Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Phe Ser 20 25 30 Asn Ser His Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5941 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5941 atctccagag acaattccaa gagcacgctg tatctgcaaa tgaacagcct gagacccgag 60 gacacggccg tatattactg tgcgaaagtg tttagcaaca gccacttctt tgactactgg 120 ggccaggga 129 <210> 5942 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5942 Ile Ser Arg Asp Asn Ser Lys Ser Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Phe Ser 20 25 30 Asn Ser His Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5943 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5943 Cys Ala Arg Asp Leu Arg Tyr Cys Gly Gly Asp Cys Tyr Ser Leu Ala 1 5 10 15 Gly Ala Phe Asp Ile Trp 20 <210> 5944 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5944 acagtctact tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agagatttac gatattgtgg tggtgactgc tattctttgg ctggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 5945 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5945 Thr Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Leu Arg Tyr Cys Gly Gly Asp Cys Tyr Ser 20 25 30 Leu Ala Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5946 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5946 acagtctaca tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agagatttac gatattgtgg tggtgactgc tattctttgg ctggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 5947 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5947 Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Leu Arg Tyr Cys Gly Gly Asp Cys Tyr Ser 20 25 30 Leu Ala Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5948 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5948 Cys Ala Arg Glu Ser Asn Ala Arg Leu Asp Trp 1 5 10 <210> 5949 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5949 ctattcacca tctccagata caatgccaag aactcactgt atctgcaaat gaacagcctg 60 agagacgagg acacggctgt gtattactgt gcgagagaat ccaacgctcg gctggactgg 120 ggccaggga 129 <210> 5950 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5950 Leu Phe Thr Ile Ser Arg Tyr Asn Ala Lys Asn Ser Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Glu Ser Asn Ala Arg Leu Asp Trp Gly Gln Gly 35 40 <210> 5951 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5951 cgattcacca tctccagaga caatgccaag aactcactgt atctgcaaat gaacagcctg 60 agagacgagg acacggctgt gtattactgt gcgagagaat ccaacgctcg gctggactgg 120 ggccaggga 129 <210> 5952 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5952 Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Glu Ser Asn Ala Arg Leu Asp Trp Gly Gln Gly 35 40 <210> 5953 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5953 Cys Ala Arg Glu Ser Tyr Cys Thr Gly Gly Val Cys Tyr Pro Asn Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 5954 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5954 aacacgctgt atcttcaaat gaacagcctg agagccgagg acacggccgt gtattactgt 60 gcgagagaaa gctattgtac tggtggtgta tgctacccca actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5955 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5955 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Ser Tyr Cys Thr Gly Gly Val Cys Tyr 20 25 30 Pro Asn Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5956 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5956 aacacgatgt atcttcaaat gaacagcctg agagccgagt acacggccgt gtattactgt 60 gcgagagaaa gctattgtac tggtggtgta tgctacccca actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5957 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5957 Asn Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Tyr Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Ser Tyr Cys Thr Gly Gly Val Cys Tyr 20 25 30 Pro Asn Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5958 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5958 Cys Ala Arg Val Leu Tyr Ser Tyr Gly Pro Gly Pro Ile Asp Tyr Trp 1 5 10 15 <210> 5959 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5959 agagacaatg ccaagaactc agtgtatctg caaatgaaca gcctgagaga cgaggacacg 60 gctgtgtatt actgtgcgag agttctgtac agctatggtc cgggacctat tgactactgg 120 ggccaggga 129 <210> 5960 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5960 Arg Asp Asn Ala Lys Asn Ser Val Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Asp Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Leu Tyr Ser Tyr 20 25 30 Gly Pro Gly Pro Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 5961 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5961 agagacaatg ccaagaactc agtgtatctg caaatgaaca gcctgagaga cgaggacacg 60 gctgtgtatt actgtgcaag agttctgtac agctatggtc caggacctat tgactactgg 120 ggccaggga 129 <210> 5962 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5962 Cys Ala Arg Gly Arg Tyr Thr Ser Glu Trp Phe Gly Glu Phe Arg Gly 1 5 10 15 Arg Asn Trp Phe Asp Pro Trp 20 <210> 5963 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5963 gcctacttgg agctgaggag cctgagatct gacgacacgg ccgtgtatta ctgtgcgaga 60 ggacggtaca cttcggaatg gttcggggag ttccgcggac gcaactggtt cgacccctgg 120 ggccaggga 129 <210> 5964 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5964 Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Gly Arg Tyr Thr Ser Glu Trp Phe Gly Glu Phe Arg 20 25 30 Gly Arg Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5965 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5965 gcctacatgg agctgaggag cctgagatct gacgacacgg ccgtgtatta ctgtgcgaga 60 ggacggtaca cttcggaatg gttcggggag ttccgcggac gcaactggtt cgacccctgg 120 ggccaggga 129 <210> 5966 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5966 Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Gly Arg Tyr Thr Ser Glu Trp Phe Gly Glu Phe Arg 20 25 30 Gly Arg Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 5967 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5967 Cys Ala His Ala Phe Lys Gly Asp Phe Val Trp Ser Thr Ile Phe His 1 5 10 15 Ala Phe Asp Ile Trp 20 <210> 5968 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5968 aatcaggtgg tccttacaat gaccaatttg gaccctgtgg acacagccac atattactgt 60 gcacacgctt ttaagggcga ttttgtctgg tcaaccatct ttcatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5969 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5969 Asn Gln Val Val Leu Thr Met Thr Asn Leu Asp Pro Val Asp Thr Ala 1 5 10 15 Thr Tyr Tyr Cys Ala His Ala Phe Lys Gly Asp Phe Val Trp Ser Thr 20 25 30 Ile Phe His Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 5970 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5970 aaccaggtgg tccttacaat gaccaatttg gaccctgtgg acacagccac atattactgt 60 gcacacgctt ttaagggcga ttttgtctgg tcaaccatct ttcatgcttt tgatatctgg 120 ggccaaggg 129 <210> 5971 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5971 Cys Ala Arg Trp Ser His Asp Tyr Gly Asp Tyr Thr Ile Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 5972 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5972 actgcctact tggagctgag gagcctgaga tctgacgaca cggccgtgta ttactgtgcg 60 agatggagcc atgactacgg tgactacacc atctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5973 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5973 Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Trp Ser His Asp Tyr Gly Asp Tyr Thr Ile Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5974 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5974 acagcctaca tggagctgag gagcctgaga tctgacgaca cggccgtgta ttactgtgcg 60 agatggagcc atgactacgg tgactacacc atctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5975 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5975 Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Trp Ser His Asp Tyr Gly Asp Tyr Thr Ile Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5976 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5976 Cys Ala Arg Val Gly Gly Tyr Ser Tyr Gly Tyr Pro His Tyr Trp 1 5 10 15 <210> 5977 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5977 tccagagaca acgccaagaa ctccctgtat ctgcaaatga acagtctgag agccgaggac 60 acggccttgt attactgtgc gagagttgga gggtacagct atggttatcc ccactactgg 120 ggccaggga 129 <210> 5978 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5978 Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Arg Val Gly Gly Tyr 20 25 30 Ser Tyr Gly Tyr Pro His Tyr Trp Gly Gln Gly 35 40 <210> 5979 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5979 tccagagaca acgccaagaa ctccctgtat ctgcaaatga acagtctgag agccgaggac 60 acggccttgt attactgtgc gagagttgga ggatacagct atggttatcc ccactactgg 120 ggccaggga 129 <210> 5980 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5980 Cys Ala Arg Ala Tyr Gly Asp Tyr Ile Leu Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 5981 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5981 tcaagagatg attccaaaag catcgcctat ctgcaaatga gcagcctgaa aaccgaggac 60 acagccgtct attactgtgc tagagcgtac ggtgactaca tattatactt tgactactgg 120 ggccaggga 129 <210> 5982 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5982 Ser Arg Asp Asp Ser Lys Ser Ile Ala Tyr Leu Gln Met Ser Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Tyr Gly Asp 20 25 30 Tyr Ile Leu Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5983 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5983 tcaagagatg attccaaaag catcgcctat ctgcaaatga acagcctgaa aaccgaggac 60 acagccgtct attactgtgc tagagcgtac ggtgactaca tattatactt tgactactgg 120 ggccaggga 129 <210> 5984 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5984 Ser Arg Asp Asp Ser Lys Ser Ile Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Tyr Gly Asp 20 25 30 Tyr Ile Leu Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5985 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5985 Cys Ala Arg Glu Asn Gly His Gly Gly Asn Ile Ala Ser Phe Asp Tyr 1 5 10 15 Trp <210> 5986 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5986 gacacatccg cgagcacagc ctacatggag ctgagcagcc tgagatctga agacgcggct 60 gtatattact gtgcgagaga aaacggccac ggtggtaaca tcgcatcctt tgactactgg 120 ggccaggga 129 <210> 5987 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5987 Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Ala Ala Val Tyr Tyr Cys Ala Arg Glu Asn Gly His Gly Gly 20 25 30 Asn Ile Ala Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5988 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5988 gacacatccg cgagcacagc ctacatggag ctgagcagcc tgagatctga agacacggct 60 gtatattact gtgcgagaga aaacggccac ggtggtaaca tcgcatcctt tgactactgg 120 ggccaggga 129 <210> 5989 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5989 Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Asn Gly His Gly Gly 20 25 30 Asn Ile Ala Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 5990 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5990 Cys Ala Arg Asp Gly Glu Tyr Ser Ser Ser Phe Tyr Gly Met Asp Val 1 5 10 15 Trp <210> 5991 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5991 tacaattcca agaacacgct gtatcttcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgcgagaga tggggaatat agcagcagct tctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5992 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5992 Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Gly Glu Tyr Ser Ser 20 25 30 Ser Phe Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5993 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5993 gacaattcca agaacacgct gtatcttcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgcgagaga tggggaatat agcagcagct tctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 5994 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5994 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Gly Glu Tyr Ser Ser 20 25 30 Ser Phe Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 5995 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5995 Cys Ala Arg Thr Asp Ile Leu Thr Gly Tyr Tyr Gln Phe Asp Tyr Trp 1 5 10 15 <210> 5996 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5996 caaggactcc tccaaaaacc aggtggtcct acaatgacca acatggaccc tgtggacaca 60 gacacatatt actgtgcacg caccgatatt ttgactggtt attatcaatt tgactactgg 120 ggccacgga 129 <210> 5997 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5997 Gln Gly Leu Leu Gln Lys Pro Gly Gly Pro Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Asp Thr Tyr Tyr Cys Ala Arg Thr Asp Ile Leu Thr 20 25 30 Gly Tyr Tyr Gln Phe Asp Tyr Trp Gly His Gly 35 40 <210> 5998 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5998 aaggactcct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gacacatatt actgtgcacg caccgatatt ttgactggtt attatcaatt tgactactgg 120 ggccacgga 129 <210> 5999 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 5999 Lys Asp Ser Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Asp Thr Tyr Tyr Cys Ala Arg Thr Asp Ile Leu Thr 20 25 30 Gly Tyr Tyr Gln Phe Asp Tyr Trp Gly His Gly 35 40 <210> 6000 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6000 Cys Ala Lys Asp Pro Ser Ala Ala Gly Thr His Tyr Phe Gln His Trp 1 5 10 15 <210> 6001 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6001 agagacaacg ccaagaactc cctgtgtctg caaatgaaca gtctgagagc tgaggacacg 60 gccttgtatt actgtgcaaa agatccgtca gcagctggta cccattactt ccagcactgg 120 gaccagggc 129 <210> 6002 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6002 Arg Asp Asn Ala Lys Asn Ser Leu Cys Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Pro Ser Ala Ala 20 25 30 Gly Thr His Tyr Phe Gln His Trp Asp Gln Gly 35 40 <210> 6003 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6003 agagacaacg ccaagaactc cctgtatctg caaatgaaca gtctgagagc tgaggacacg 60 gccttgtatt actgtgcaaa agatccgtca gcagctggta cccattactt ccagcactgg 120 ggccagggc 129 <210> 6004 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6004 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Pro Ser Ala Ala 20 25 30 Gly Thr His Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 6005 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6005 Cys Ala Lys Gly Gly Trp Leu Asp Asp Trp 1 5 10 <210> 6006 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6006 ggccgattca tcatctccag atataattcc aagaacatga cgtttctgca aatggacagg 60 ttgagaggcg acgacacggc cgtatattac tgtgcgaaag ggggctggct tgacgactgg 120 ggccaggga 129 <210> 6007 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6007 Gly Arg Phe Ile Ile Ser Arg Tyr Asn Ser Lys Asn Met Thr Phe Leu 1 5 10 15 Gln Met Asp Arg Leu Arg Gly Asp Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Lys Gly Gly Trp Leu Asp Asp Trp Gly Gln Gly 35 40 <210> 6008 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6008 ggccgattca tcatctccag agataattcc aagaacatga cgtttctgca aatggacagg 60 ttgagaggcg acgacacggc cgtatattac tgtgcgaaag ggggctggct tgacgactgg 120 ggccaggga 129 <210> 6009 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6009 Gly Arg Phe Ile Ile Ser Arg Asp Asn Ser Lys Asn Met Thr Phe Leu 1 5 10 15 Gln Met Asp Arg Leu Arg Gly Asp Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Lys Gly Gly Trp Leu Asp Asp Trp Gly Gln Gly 35 40 <210> 6010 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6010 Cys Ala Arg Asp Gly Pro Gln Asp Tyr Gly Asp Asn Ser Tyr Tyr Tyr 1 5 10 15 Tyr Tyr Tyr Gly Met Asp Val Trp 20 <210> 6011 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6011 tttatgcaaa tgaacagcct gagagacgag gacacggctg tgtattactg tgcgagagat 60 ggaccccaag actacggtga caactcctat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6012 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6012 Phe Met Gln Met Asn Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Asp Gly Pro Gln Asp Tyr Gly Asp Asn Ser Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6013 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6013 tatctgcaaa tgaacagcct gagagacgag gacacggctg tgtattactg tgcgagagat 60 ggaccccaag actacggtga caactcctat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6014 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6014 Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Asp Gly Pro Gln Asp Tyr Gly Asp Asn Ser Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6015 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6015 Cys Ala Arg Asp Leu Glu Pro Trp Tyr Phe Asp Val Trp 1 5 10 <210> 6016 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6016 accatctcca gagacaatgc caagaattta ttgtatctgc aaatgaccag gctgagagac 60 gacgacacgg ctgtgtatta ctgtgcgcga gatctcgagc cctggtactt cgatgtctgg 120 ggccgtggc 129 <210> 6017 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6017 Thr Ile Ser Arg Asp Asn Ala Lys Asn Leu Leu Tyr Leu Gln Met Thr 1 5 10 15 Arg Leu Arg Asp Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu 20 25 30 Glu Pro Trp Tyr Phe Asp Val Trp Gly Arg Gly 35 40 <210> 6018 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6018 aacatctcca tagacaatgc caagaattta ttgtatctgc aaatgaccag gctgagagac 60 gacgacacgg ctgtgtatta ctgtgcgcga gatctcgagc cctggtactt cgatgtctgg 120 ggccgtggc 129 <210> 6019 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6019 Asn Ile Ser Ile Asp Asn Ala Lys Asn Leu Leu Tyr Leu Gln Met Thr 1 5 10 15 Arg Leu Arg Asp Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu 20 25 30 Glu Pro Trp Tyr Phe Asp Val Trp Gly Arg Gly 35 40 <210> 6020 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6020 Cys Thr Thr Asp Asp Tyr Gly Asp Tyr Arg Arg Tyr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 6021 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6021 aaaaacacgc tgtatctgca aatgaacagc ctgaaaaccg aggacatagc cgtgtattac 60 tgtaccacag acgactacgg tgactaccga aggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6022 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6022 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Ile 1 5 10 15 Ala Val Tyr Tyr Cys Thr Thr Asp Asp Tyr Gly Asp Tyr Arg Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6023 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6023 aaaaacacgc tgtatctgca aatgaacagc ctgaaaaccg aggacacagc cgtgtattac 60 tgtaccacag acgactacgg tgactaccga aggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6024 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6024 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Thr Thr Asp Asp Tyr Gly Asp Tyr Arg Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6025 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6025 Cys Gly Arg Leu His Tyr Asp Gly Leu Gly His Asp Ala Phe Asp Ile 1 5 10 15 Trp <210> 6026 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6026 gacacatcct cgagcacagc ctacatggag ctgaggagcc tgagatctga cgacacggcc 60 gtgtattact gtgggcgtct ccactatgac ggtttgggtc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6027 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6027 Asp Thr Ser Ser Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Gly Arg Leu His Tyr Asp Gly Leu 20 25 30 Gly His Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6028 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6028 gacacatcca cgagcacagc ctacatggag ctgaggagcc tgagatctga cgacacggcc 60 gtgtattact gtgggcgtct ccactatgac ggtttgggtc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6029 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6029 Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Gly Arg Leu His Tyr Asp Gly Leu 20 25 30 Gly His Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6030 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6030 Cys Ala Lys Val Gly Val Gly Ala Gly Ala Leu Asp Tyr Trp 1 5 10 <210> 6031 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6031 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagtc ggggttggag cgggagccct tgactactgg 120 ggccaggga 129 <210> 6032 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6032 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Val 20 25 30 Gly Ala Gly Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6033 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6033 atctccacac ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagtc ggggttggag cgggagccct tgactactgg 120 ggccaggga 129 <210> 6034 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6034 Ile Ser Thr His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Val 20 25 30 Gly Ala Gly Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6035 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6035 Cys Ala Arg Ala Arg Gly Val Gly Arg Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 6036 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6036 tccagagaaa atgccaagaa ctccttgtat cttcaaatga acagcctgag agccggggac 60 acggctgtgt attactgtgc aagagccagg ggagtgggac ggtactactt tgactactgg 120 ggccaggga 129 <210> 6037 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6037 Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Arg Gly Val 20 25 30 Gly Arg Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6038 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6038 tacagagaaa atgccaagaa ctccttgtat cttcaaatga acagcctgag agccggtgac 60 acggctgtgt attactgtgc aagagccagg ggagtgggac ggtactactt tgactactgg 120 ggccaggga 129 <210> 6039 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6039 Tyr Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Arg Gly Val 20 25 30 Gly Arg Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6040 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6040 Cys Ala Arg Phe Gln Arg Ser Phe Gly Tyr Phe Asp Tyr Trp 1 5 10 <210> 6041 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6041 atctcagccg acaggtccat caccaccgcc ttcctgcagt gggacagtct gaaggcctcg 60 gacaccgccc tttatttctg tgcgagattc caacgcagtt tcggctattt tgactactgg 120 ggccaggga 129 <210> 6042 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6042 Ile Ser Ala Asp Arg Ser Ile Thr Thr Ala Phe Leu Gln Trp Asp Ser 1 5 10 15 Leu Lys Ala Ser Asp Thr Ala Leu Tyr Phe Cys Ala Arg Phe Gln Arg 20 25 30 Ser Phe Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6043 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6043 tctcagcccg acaggtccat caccaccgcc ttcctgcagt gggacagtct gaaggcctcg 60 gacaccgccc tttatttctg tgcgagattc caacgcagtt tcggctattt tgactactgg 120 ggccaggga 129 <210> 6044 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6044 Ser Gln Pro Asp Arg Ser Ile Thr Thr Ala Phe Leu Gln Trp Asp Ser 1 5 10 15 Leu Lys Ala Ser Asp Thr Ala Leu Tyr Phe Cys Ala Arg Phe Gln Arg 20 25 30 Ser Phe Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6045 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6045 Cys Ala Arg Gly Gly Ile Gln Val Pro Gly Leu Asp Asp Val Phe Asp 1 5 10 15 Ile Trp <210> 6046 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6046 gacgccaaaa actccttgta tcttcaaatg aacagcctga gagacgggga cacggctgtt 60 tattactgtg ccaggggagg tatacaagtg cctggcctag atgatgtctt tgatatctgg 120 ggccaaggg 129 <210> 6047 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6047 Asp Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp Gly 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Ile Gln Val Pro Gly 20 25 30 Leu Asp Asp Val Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6048 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6048 agacgccaaa actccttgta tcttcaaatg aacagcctga gagacgggga cacggctgtt 60 tattactgtg ccaggggagg tatacaagtg cctggcctag atgatgtctt tgatatctgg 120 ggccaaggg 129 <210> 6049 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6049 Arg Arg Gln Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp Gly 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Ile Gln Val Pro Gly 20 25 30 Leu Asp Asp Val Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6050 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6050 Cys Ala Arg Gly Tyr Ile Thr Gly Thr Trp Asp Tyr Trp 1 5 10 <210> 6051 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6051 accatgacca ggaacacctc cataagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ggatacataa ctggaacgtg ggactactgg 120 ggccaggga 129 <210> 6052 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6052 Thr Met Thr Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Tyr 20 25 30 Ile Thr Gly Thr Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 6053 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6053 accatgacca gcaacacctc cataagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ggatacataa ctggaacgtg ggactactgg 120 ggccaggga 129 <210> 6054 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6054 Thr Met Thr Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Tyr 20 25 30 Ile Thr Gly Thr Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 6055 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6055 Cys Ala Lys Asp Arg Ser Ser Tyr Gly Ala Gly Gly Met Asp Val Trp 1 5 10 15 <210> 6056 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6056 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggactcg 60 gctgtctatt actgtgcgaa agatagaagc agttatggag cggggggtat ggacgtctgg 120 ggccaaggg 129 <210> 6057 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6057 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Ser Ala Val Tyr Tyr Cys Ala Lys Asp Arg Ser Ser Tyr 20 25 30 Gly Ala Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6058 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6058 agagacaatt ccaagaacac gctgtacctg caaatgaaca gcctgagagc cgaggactcg 60 gctgtctatt actgtgcgaa agatagaagc agttatggag cagggggtat ggacgtctgg 120 ggccaaggg 129 <210> 6059 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6059 Cys Ala Arg Asp Arg Thr Gly Gly Tyr Leu Phe Asp Tyr Trp 1 5 10 <210> 6060 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6060 atcaacccag acacatccaa gaaccagttc tccctgcagc tgaactctgt ggctcccgag 60 gacacggctg tgtattactg tgcaagagat cgcactggtg gttacttatt tgactactgg 120 ggccaggga 129 <210> 6061 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6061 Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser 1 5 10 15 Val Ala Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Thr 20 25 30 Gly Gly Tyr Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6062 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6062 atcaacccag acacatccaa gaaccagttc tccctgcagc tgaactctgc ggctcccgag 60 gacacggctg tgtattactg tgcaagagat cgcactggtg gctacttatt tgactactgg 120 ggccaggga 129 <210> 6063 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6063 Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser 1 5 10 15 Ala Ala Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Thr 20 25 30 Gly Gly Tyr Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6064 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6064 Cys Ala Arg Gly Gly Gly Trp Gly Arg Thr Thr Leu Pro Pro Asp Tyr 1 5 10 15 Trp <210> 6065 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6065 gacacgtcta agaaccagtt ctccctgaag ctgagctctg tgactgccgc ggacacggcc 60 gtgtattact gtgcgagagg ggggggttgg ggcaggacta ctttaccccc cgactactgg 120 ggccaggga 129 <210> 6066 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6066 Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala 1 5 10 15 Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Gly Trp Gly Arg 20 25 30 Thr Thr Leu Pro Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 6067 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6067 gacacgtcta agaaccagtt ctccctgaag ctgagctctg tgactgccgc ggacacggcc 60 gtgtattact gtgcgagagg gggggggtgg ggcaggacta ctttaccccc cgactactgg 120 ggccaggga 129 <210> 6068 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6068 Cys Ala Arg Asp Gln Leu Val Leu Glu Trp Leu Tyr Pro Thr Pro Asp 1 5 10 15 Ala Phe Asp Ile Trp 20 <210> 6069 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6069 agcactgcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatc agctggtttt ggagtggtta tatccaacac ccgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6070 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6070 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Gln Leu Val Leu Glu Trp Leu Tyr Pro 20 25 30 Thr Pro Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6071 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6071 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatc agctggtttt ggagtggtta tatccaacac ccgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6072 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6072 Cys Ala Arg Gly Tyr Ser Gly Ser Tyr Tyr Gly Glu Val Asp Tyr Trp 1 5 10 15 <210> 6073 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6073 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacgtatt actgtgcacg ggggtatagt gggagctact acggggaggt tgactactgg 120 ggccaggga 129 <210> 6074 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6074 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Gly Tyr Ser Gly Ser 20 25 30 Tyr Tyr Gly Glu Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 6075 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6075 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacgtatt actgtgcacg ggggtatagt gggagctact acggggaggt tgactactgg 120 ggccaggga 129 <210> 6076 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6076 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Gly Tyr Ser Gly Ser 20 25 30 Tyr Tyr Gly Glu Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 6077 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6077 Cys Ala Lys Val Arg Asp Ile Glu Arg Thr Trp 1 5 10 <210> 6078 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6078 cggttcacca tctccagaga caattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaagtga gggatattga aaggacttgg 120 ggccaggga 129 <210> 6079 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6079 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Val Arg Asp Ile Glu Arg Thr Trp Gly Gln Gly 35 40 <210> 6080 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6080 cggttcacca tctccagaca caattccaag aacacgctgt atctgcaaat caacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaagtga gggatattga aaggacttgg 120 ggccaggga 129 <210> 6081 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6081 Arg Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Val Arg Asp Ile Glu Arg Thr Trp Gly Gln Gly 35 40 <210> 6082 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6082 Cys Thr Arg Pro Arg Pro Cys Phe Glu Ser His Gly Tyr Asp Cys Asn 1 5 10 15 Val Phe Asp Met Trp 20 <210> 6083 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6083 aatacggcgt atctgcaaat gaacagcctg aaaaccgagg acacggccat gtattattgt 60 actagaccgc gtccgtgctt tgagagtcat ggttatgact gcaatgtttt tgatatgtgg 120 ggccaaggg 129 <210> 6084 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6084 Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala 1 5 10 15 Met Tyr Tyr Cys Thr Arg Pro Arg Pro Cys Phe Glu Ser His Gly Tyr 20 25 30 Asp Cys Asn Val Phe Asp Met Trp Gly Gln Gly 35 40 <210> 6085 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6085 aacacggcgt atctgcaaat gaacagcctg aaaaccgagg acacggccat gtattattgt 60 actagaccgc gtccgtgctt tgagagtcat ggttatgact gcaatgtttt tgatatgtgg 120 ggccaaggg 129 <210> 6086 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6086 Cys Ala Arg Glu Ser Leu Ile Thr Val Thr Asn Asn Trp Phe Asp Ser 1 5 10 15 Trp <210> 6087 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6087 gacaacgcca agaactccct gtatctgcaa atgaacagtc tgaaggccga ggacacggcc 60 ttctactact gtgcgagaga gtccctgatt acggtgacca acaactggtt cgactcttgg 120 ggccaggga 129 <210> 6088 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6088 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Lys Ala 1 5 10 15 Glu Asp Thr Ala Phe Tyr Tyr Cys Ala Arg Glu Ser Leu Ile Thr Val 20 25 30 Thr Asn Asn Trp Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 6089 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6089 gacaacgcca agaactccct gtatctgcaa atgaacagtc tgaaagccga ggacacggcc 60 ttctactact gtgcgagaga gtccctgatt acggtgacca acaactggtt cgactcttgg 120 ggccaggga 129 <210> 6090 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6090 Cys Ala Arg Ser His Glu Trp Glu Leu Leu Asn Phe Asp Tyr Trp 1 5 10 15 <210> 6091 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6091 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaggtcccat gagtgggagc tactaaactt tgactactgg 120 ggccaggga 129 <210> 6092 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6092 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ser His Glu Trp 20 25 30 Glu Leu Leu Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6093 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6093 tacagatata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaggtcccat gagtgggagc tactaaactt tgactactgg 120 ggccaggga 129 <210> 6094 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6094 Tyr Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ser His Glu Trp 20 25 30 Glu Leu Leu Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6095 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6095 Cys Glu Arg Met Gly Ile Ala Val Ala Gly Ile Trp Gly Tyr Trp 1 5 10 15 <210> 6096 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6096 ctcaagcaac accctttaag tgcagtctgc cttacaatga ccaatctgaa agccaaggac 60 aaggtcatgt attactgtga aagaatgggt atagcagtgg ctggtatatg gggctactgg 120 ggccaggga 129 <210> 6097 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6097 Leu Lys Gln His Pro Leu Ser Ala Val Cys Leu Thr Met Thr Asn Leu 1 5 10 15 Lys Ala Lys Asp Lys Val Met Tyr Tyr Cys Glu Arg Met Gly Ile Ala 20 25 30 Val Ala Gly Ile Trp Gly Tyr Trp Gly Gln Gly 35 40 <210> 6098 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6098 tcaagcaaca cccttttaag tgcagtctgc cttacaatga ccaatctgaa agccaaggac 60 aaggtcatgt attactgtga aagaatgggt atagcagtgg ctggtatatg gggctactgg 120 ggccaggga 129 <210> 6099 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6099 Ser Ser Asn Thr Leu Leu Ser Ala Val Cys Leu Thr Met Thr Asn Leu 1 5 10 15 Lys Ala Lys Asp Lys Val Met Tyr Tyr Cys Glu Arg Met Gly Ile Ala 20 25 30 Val Ala Gly Ile Trp Gly Tyr Trp Gly Gln Gly 35 40 <210> 6100 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6100 Cys Ala Lys Asp Leu Gly Ser Pro Gly Arg Gln Ala Ala Asp Tyr Trp 1 5 10 15 <210> 6101 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6101 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatttggga tcacctggaa gacaggcagc tgactactgg 120 ggccaggga 129 <210> 6102 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6102 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Gly Ser Pro 20 25 30 Gly Arg Gln Ala Ala Asp Tyr Trp Gly Gln Gly 35 40 <210> 6103 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6103 agagacaatc tcaggaatac cctctatttg caaatgaaca gcctgagagc cgaggacacg 60 gccgtttatt actgtgcgaa agatttggga tcacctggaa gacaggcagc tgactactgg 120 ggccaggga 129 <210> 6104 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6104 Arg Asp Asn Leu Arg Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Gly Ser Pro 20 25 30 Gly Arg Gln Ala Ala Asp Tyr Trp Gly Gln Gly 35 40 <210> 6105 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6105 Cys Ala Arg Tyr Gly Gly Tyr Asp Glu Ala Phe Asp Tyr Trp 1 5 10 <210> 6106 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6106 ttgtcagtag acacgtccaa gaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggccg tgtattactg tgcgagatac ggggggtacg atgaggcgtt tgactactgg 120 ggccaggga 129 <210> 6107 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6107 Leu Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Tyr Gly Gly 20 25 30 Tyr Asp Glu Ala Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6108 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6108 atgtcagtag acacgtccaa gaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggccg tgtattactg tgcgagatac ggggggtacg atgaggcgtt tgactactgg 120 ggccaggga 129 <210> 6109 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6109 Met Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Tyr Gly Gly 20 25 30 Tyr Asp Glu Ala Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6110 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6110 Cys Ala Arg Ser Thr His Asp Phe Trp Ser Gly Ser Phe Pro Ser Gly 1 5 10 15 Gln Gly Phe Asp Pro Trp 20 <210> 6111 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6111 ctgttctccc tgatgctgag ctctgtgacc gccgcagaca cggccgtgta ttactgtgcg 60 agatctactc acgatttttg gagtggttcc ttcccctcag gccaggggtt cgacccctgg 120 ggccaggga 129 <210> 6112 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6112 Leu Phe Ser Leu Met Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Ser Thr His Asp Phe Trp Ser Gly Ser Phe Pro 20 25 30 Ser Gly Gln Gly Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6113 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6113 cagttctccc tgaagctgag ctctgtgacc gccgcagaca cggccgtgta ttactgtgcg 60 agatctactc acgatttttg gagtggttcc ttcccctcag gccaggggtt cgacccctgg 120 ggccaggga 129 <210> 6114 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6114 Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Ser Thr His Asp Phe Trp Ser Gly Ser Phe Pro 20 25 30 Ser Gly Gln Gly Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6115 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6115 Cys Ala Arg Val Gly Tyr Ala Tyr Gly Leu Asp His Trp 1 5 10 <210> 6116 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6116 accttatcag ttgacacgtc taagaaccac ttctccctga aggtgagctc tgtgactgct 60 gcggacacgg ccgtatatta ctgtgcgaga gttgggtacg cctatggtct tgaccactgg 120 ggccaggga 129 <210> 6117 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6117 Thr Leu Ser Val Asp Thr Ser Lys Asn His Phe Ser Leu Lys Val Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly 20 25 30 Tyr Ala Tyr Gly Leu Asp His Trp Gly Gln Gly 35 40 <210> 6118 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6118 accttatcag ttgacacgtc taagaaccac ttctccctga aggtgacctc tgtgaccgct 60 gcggacacgg ccgtgtatta ctgtgcgaga gttggatacg cctatggtct tgaccactgg 120 ggccaggga 129 <210> 6119 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6119 Thr Leu Ser Val Asp Thr Ser Lys Asn His Phe Ser Leu Lys Val Thr 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly 20 25 30 Tyr Ala Tyr Gly Leu Asp His Trp Gly Gln Gly 35 40 <210> 6120 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6120 Cys Ala Lys Asp Lys Leu Phe Ala Ser Val Pro Gly Pro Phe Asp Ser 1 5 10 15 Trp <210> 6121 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6121 cacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga taaacttttc gcttcggtcc ccggtccatt tgactcctgg 120 ggccaggga 129 <210> 6122 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6122 His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Lys Leu Phe Ala Ser 20 25 30 Val Pro Gly Pro Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 6123 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6123 gacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga taaacttttc gcttcggtcc ccggtccatt tgactcctgg 120 ggccaggga 129 <210> 6124 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6124 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Lys Leu Phe Ala Ser 20 25 30 Val Pro Gly Pro Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 6125 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6125 Cys Ala Arg Glu Gly Thr Gly Val Phe Asp Tyr Trp 1 5 10 <210> 6126 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6126 gtcaccttta ccgcggacaa atccacgggc acagcctaca tggagttgag aggcctgaga 60 tctgaggaca cggccgtgta tttctgtgcg agagagggga ctggcgtctt tgactactgg 120 ggccaggga 129 <210> 6127 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6127 Val Thr Phe Thr Ala Asp Lys Ser Thr Gly Thr Ala Tyr Met Glu Leu 1 5 10 15 Arg Gly Leu Arg Ser Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Glu 20 25 30 Gly Thr Gly Val Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6128 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6128 gtcaccttta ccgcgcacaa atccacgggc acagcctaca tggagttgag aggcctgaga 60 tctgaggaca cggccgtgta tttctgtgcg agagagggga ctggcgtctt tgactactgg 120 ggccaggga 129 <210> 6129 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6129 Val Thr Phe Thr Ala His Lys Ser Thr Gly Thr Ala Tyr Met Glu Leu 1 5 10 15 Arg Gly Leu Arg Ser Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Glu 20 25 30 Gly Thr Gly Val Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6130 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6130 Cys Ala Lys Asp Gly Ser Gly Thr Ile Phe Gly Val Val Ile Ala Lys 1 5 10 15 Tyr Tyr Phe Asp Tyr Trp 20 <210> 6131 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6131 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagacggtt ccggtacgat ttttggagtg gttatcgcca aatactactt tgactactgg 120 ggccaggga 129 <210> 6132 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6132 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Gly Ser Gly Thr Ile Phe Gly Val Val Ile 20 25 30 Ala Lys Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6133 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6133 acgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagacggtt ccggtacgat ttttggagtg gttatcgcca aatactactt tgactactgg 120 ggccaggga 129 <210> 6134 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6134 Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Gly Ser Gly Thr Ile Phe Gly Val Val Ile 20 25 30 Ala Lys Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6135 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6135 Cys Ala Ser Gly Ser Gly Pro Gly Leu Trp Leu Glu Tyr Trp 1 5 10 <210> 6136 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6136 atctccatac acaattccaa gaacacgctg tatcttcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagcggg tccgggccgg ggctatggtt agaatactgg 120 ggccaggga 129 <210> 6137 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6137 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly Ser Gly 20 25 30 Pro Gly Leu Trp Leu Glu Tyr Trp Gly Gln Gly 35 40 <210> 6138 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6138 atctccagag acaattccaa gaacacgctg tatcttcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagcggg tccgggccgg ggctatggtt agaatactgg 120 ggccaggga 129 <210> 6139 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6139 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly Ser Gly 20 25 30 Pro Gly Leu Trp Leu Glu Tyr Trp Gly Gln Gly 35 40 <210> 6140 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6140 Cys Ala Asn Ser Leu Pro Gln Ser Gly Tyr Glu Asp Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 6141 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6141 tacacgctgt atctgcaaat caacagcctg agagccgagg acacggccgt atattactgt 60 gcgaacagcc tccctcaaag tggctacgaa gactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6142 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6142 Tyr Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Asn Ser Leu Pro Gln Ser Gly Tyr Glu Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6143 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6143 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaacagcc tccctcaaag tggctacgaa gactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6144 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6144 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Asn Ser Leu Pro Gln Ser Gly Tyr Glu Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6145 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6145 Cys Ala Arg Asp Leu Asp Ser Ser Tyr Gly Met Asp Val Trp 1 5 10 <210> 6146 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6146 ttgaccaggg acacgtccac gagcacagtc tacatggagc tgagcagcct gatatctgag 60 gacacggccg tgtattactg tgcgagagat ctggactcat cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6147 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6147 Leu Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Ile Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu Asp 20 25 30 Ser Ser Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6148 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6148 atgaccaggg acacgtccac gagcacagtc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagagat ctggactcat cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6149 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6149 Met Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu Asp 20 25 30 Ser Ser Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6150 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6150 Cys Ala Arg Thr Val Phe Tyr Ser Gly Ser Tyr Leu Leu Phe Asp Tyr 1 5 10 15 Trp <210> 6151 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6151 gacacctcca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acgtattact gtgcacggac cgtcttttat agtgggagct accttctctt tgactactgg 120 ggccaggga 129 <210> 6152 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6152 Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Thr Val Phe Tyr Ser Gly 20 25 30 Ser Tyr Leu Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6153 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6153 ggacacctcc aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acgtattact gtgcacggac cgtcttttat agtgggagct accttctctt tgactactgg 120 ggccaggga 129 <210> 6154 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6154 Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Thr Val Phe Tyr Ser Gly 20 25 30 Ser Tyr Leu Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6155 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6155 Cys Ala His Leu Ser Arg Asp Gly Tyr Asn Pro Trp 1 5 10 <210> 6156 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6156 gctcaccatc accaaggaca cctccaaaac caggtggtcc ttacaatgac caacatggac 60 cctgtggaca cagccacata ttactgtgca cacctgtcgc gagatggcta caatccgtgg 120 ggccaggga 129 <210> 6157 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6157 Ala His His His Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met 1 5 10 15 Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Leu 20 25 30 Ser Arg Asp Gly Tyr Asn Pro Trp Gly Gln Gly 35 40 <210> 6158 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6158 ctcaccatca ccaaggacac ctccaaaaac caggtggtcc ttacaatgac caacatggac 60 cctgtggaca cagccacata ttactgtgca cacctgtcgc gagatggcta caatccgtgg 120 ggccaggga 129 <210> 6159 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6159 Leu Thr Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met 1 5 10 15 Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Leu 20 25 30 Ser Arg Asp Gly Tyr Asn Pro Trp Gly Gln Gly 35 40 <210> 6160 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6160 Cys Thr Thr Val Ser Ile Ala Thr Arg Gly Tyr Tyr Tyr Tyr Gly Met 1 5 10 15 Asp Val Trp <210> 6161 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6161 tcaaaaaaca cgctgtatct gcaaatgaac agcctgaaaa ccgaggacac agccgtgtat 60 tactgtacca cagtgagtat agcaactcga ggctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6162 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6162 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Thr Val Ser Ile Ala Thr Arg Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6163 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6163 ttcaaaaaca cgctgtatct gcaaatgaac agcctgaaaa ccgaggacac agccgtgtat 60 tactgtacca cagtgagtat agcaactcga ggctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6164 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6164 Phe Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Thr Val Ser Ile Ala Thr Arg Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6165 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6165 Cys Ala Arg Asp Thr Thr Thr Glu Arg Trp Met Asp Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 6166 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6166 tgcacagcct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagata ccaccacgga gcgttggatg gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6167 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6167 Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Thr Thr Thr Glu Arg Trp Met Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6168 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6168 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagata ccaccacgga gcgttggatg gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6169 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6169 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Thr Thr Thr Glu Arg Trp Met Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6170 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6170 Cys Ala Lys Asp Ser Gly Ile Ala Val Ala Gly Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 6171 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6171 agagacaacg ccaagagctc cctgtatctg cagatgaaca gtctgagagc tgaggacacg 60 gccttgtatt actgtgcaaa agatagtggt atagcagtgg ctggctactt tgactactgg 120 ggccaggga 129 <210> 6172 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6172 Arg Asp Asn Ala Lys Ser Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Ser Gly Ile Ala 20 25 30 Val Ala Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6173 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6173 agagacaacg ccaagaactc cctgtatctg caaatgaaca gtctgagagc tgaggacacg 60 gccttgtatt actgtgcaaa agatagtggt atagcagtgg ctggctactt tgactactgg 120 ggccaggga 129 <210> 6174 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6174 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Ser Gly Ile Ala 20 25 30 Val Ala Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6175 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6175 Cys Ala Thr Tyr Ser Ser Ser Ser Ser Arg Trp Phe Asp Pro Trp 1 5 10 15 <210> 6176 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6176 tccagagaca tttccaagaa tatgttgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc tacatatagt agctcgtctt ccaggtggtt cgacccctgg 120 ggccaggga 129 <210> 6177 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6177 Ser Arg Asp Ile Ser Lys Asn Met Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Tyr Ser Ser Ser 20 25 30 Ser Ser Arg Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6178 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6178 tacagagaca tttccaataa tatgttgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc tacatatagt agctcgtctt ccaggtggtt cgacccctgg 120 ggccaggga 129 <210> 6179 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6179 Tyr Arg Asp Ile Ser Asn Asn Met Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Tyr Ser Ser Ser 20 25 30 Ser Ser Arg Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6180 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6180 Cys Ala Arg Ser Arg Ser Arg Leu Tyr Ala Phe Asp Ile Trp 1 5 10 <210> 6181 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6181 attaccaggg acaggtctat gagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacgcagcca tgtattactg tgcaagatca cggtcccgat tgtatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6182 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6182 Ile Thr Arg Asp Arg Ser Met Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Ala Ala Met Tyr Tyr Cys Ala Arg Ser Arg Ser 20 25 30 Arg Leu Tyr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6183 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6183 attaccaggg acaggtctat gagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacagcca tgtattactg tgcaagatca cggtcccgat tgtatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6184 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6184 Ile Thr Arg Asp Arg Ser Met Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Met Tyr Tyr Cys Ala Arg Ser Arg Ser 20 25 30 Arg Leu Tyr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6185 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6185 Cys Thr Arg His Asn Trp Asn Phe Glu Tyr Asn Trp Phe Asp Pro Trp 1 5 10 15 <210> 6186 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6186 agatatgatt caaacaacac ggcgtatctg caaatgaaca gcctgaaaac cgaggacacg 60 gccgtgtatt actgtactag acataactgg aacttcgagt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 6187 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6187 Arg Tyr Asp Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys 1 5 10 15 Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg His Asn Trp Asn Phe 20 25 30 Glu Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6188 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6188 agagatgatt caaagaacac ggcgtatctg caaatgaaca gcctgaaaac cgaggacacg 60 gccgtgtatt actgtactag acataactgg aacttcgagt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 6189 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6189 Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys 1 5 10 15 Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg His Asn Trp Asn Phe 20 25 30 Glu Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6190 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6190 Cys Ala Arg Asp Glu Val Arg Tyr Phe Asp Tyr Trp 1 5 10 <210> 6191 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6191 gtcaccatat cagtagacac gtccaagaac cagttctccc tgaagctgag ctctgtgacc 60 gccgcggaca cggccgtgta ttactgtgcg agagatgagg tccgatactt tgactactgg 120 ggccaggga 129 <210> 6192 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6192 Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu 1 5 10 15 Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Glu Val Arg Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6193 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6193 gtcaccatat cagtacacac gtccaagaac cagttctccc tgaagctgag ctctgtgacc 60 gccgcggaca cggccgtgta ttactgtgcg agagatgagg tccgatactt tgactactgg 120 ggccaggga 129 <210> 6194 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6194 Val Thr Ile Ser Val His Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu 1 5 10 15 Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Glu Val Arg Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6195 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6195 Cys Ala Arg Gln Tyr Tyr Asp Tyr Val Trp Gly Ser Tyr Arg His Phe 1 5 10 15 Asp Tyr Trp <210> 6196 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6196 gccaaaaccc cggtggtcct tacaatgacc aacatggacc ctgtggacac agccacatat 60 tactgtgcac gacagtatta tgattacgtt tgggggagtt atcgccactt tgactactgg 120 ggccaggga 129 <210> 6197 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6197 Ala Lys Thr Pro Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala Arg Gln Tyr Tyr Asp Tyr Val Trp Gly 20 25 30 Ser Tyr Arg His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6198 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6198 gccaaaaacc aggtggtcct tacaatgacc aacatggacc ctgtggacac agccacatat 60 tactgtgcac gacagtatta tgattacgtt tgggggagtt atcgccactt tgactactgg 120 ggccaggga 129 <210> 6199 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6199 Ala Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala Arg Gln Tyr Tyr Asp Tyr Val Trp Gly 20 25 30 Ser Tyr Arg His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6200 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6200 Cys Ala Arg Glu Gly Arg Ala Thr Glu Ser Gly Met Asp Val Trp 1 5 10 15 <210> 6201 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6201 accaggaaca cctccataag cacagcctac atggggctga gcagcctgag atctgaggac 60 acggccgtgt attactgtgc gagagaggga cgggctacgg agtccggtat ggacgtctgg 120 ggccaaggg 129 <210> 6202 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6202 Thr Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Gly Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly Arg Ala 20 25 30 Thr Glu Ser Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6203 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6203 accaggaaca cctccataag cacagcctac atggagctga gcagcctgag atctgaggac 60 acggccgtgt attactgtgc gagagaggga cgggctacgg agtccggtat ggacgtctgg 120 ggccaaggg 129 <210> 6204 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6204 Thr Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly Arg Ala 20 25 30 Thr Glu Ser Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6205 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6205 Cys Ala His Arg Leu Tyr Asn Trp Phe Asp Pro Trp 1 5 10 <210> 6206 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6206 actcaccatc accaaggaca cctccaaaac caggtggtcc ttacaatgac cgacttggac 60 cctgtggaca cagccacata ttactgtgca cacagactct ataattggtt cgacccctgg 120 ggccaggga 129 <210> 6207 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6207 Thr His His His Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met 1 5 10 15 Thr Asp Leu Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg 20 25 30 Leu Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6208 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6208 ctcaccatca ccaaggacac ctccaaaaac caggtggtcc ttacaatgac cgacttggac 60 cctgtggaca cagccacata ttactgtgca cacagactct ataattggtt cgacccctgg 120 ggccaggga 129 <210> 6209 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6209 Leu Thr Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met 1 5 10 15 Thr Asp Leu Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg 20 25 30 Leu Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6210 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6210 Cys Ala Arg Tyr Cys Ser Ser Thr Thr Cys Tyr Val Pro Glu Gly His 1 5 10 15 Tyr Tyr Ser Met Asp Val Trp 20 <210> 6211 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6211 ctttatctgc aaatgaacag cctgcgagac gaggacacgg gtgtctatta ctgtgcgaga 60 tattgtagta gtaccacctg ctatgtcccg gaggggcact actactctat ggacgtctgg 120 ggccgaggg 129 <210> 6212 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6212 Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp Thr Gly Val Tyr 1 5 10 15 Tyr Cys Ala Arg Tyr Cys Ser Ser Thr Thr Cys Tyr Val Pro Glu Gly 20 25 30 His Tyr Tyr Ser Met Asp Val Trp Gly Arg Gly 35 40 <210> 6213 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6213 ctttatctgc aaatgaacag cctgagagac gaggacacgg gtgtatatta ctgtgcgaga 60 tattgtagta gtaccacctg ctatgtcccg gaggggcact actactctat ggacgtctgg 120 ggccgaggg 129 <210> 6214 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6214 Cys Ala Arg Asp Lys Asn Gly Asp Tyr Tyr Phe Asp Ser Trp 1 5 10 <210> 6215 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6215 ttatcagtag acacgtccaa gaaccagttc tccctgaacc tgagctctgt gaccgccgcg 60 gacacggccg tgtattattg tgcgagagat aaaaacggtg actactactt tgactcctgg 120 ggccaggga 129 <210> 6216 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6216 Leu Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Asn Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Lys Asn 20 25 30 Gly Asp Tyr Tyr Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 6217 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6217 atatcagtag acacgtccaa gaaccagttc tccctgaacc tgagctctgt gaccgccgcg 60 gacacggccg tgtattattg tgcgagagat aaaaacggtg actactactt tgactcctgg 120 ggccaggga 129 <210> 6218 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6218 Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Asn Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Lys Asn 20 25 30 Gly Asp Tyr Tyr Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 6219 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6219 Cys Ala Arg Asp Leu Asp Thr Met Ile Val Val Val Lys Ala Asp Asp 1 5 10 15 Ala Phe Asp Ile Trp 20 <210> 6220 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6220 agcactgcct acatggagct gtggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagatc tggatactat gatagtagtg gttaaggccg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6221 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6221 Ser Thr Ala Tyr Met Glu Leu Trp Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Leu Asp Thr Met Ile Val Val Val Lys 20 25 30 Ala Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6222 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6222 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagatc tggatactat gatagtagtg gttaaggccg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6223 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6223 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Leu Asp Thr Met Ile Val Val Val Lys 20 25 30 Ala Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6224 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6224 Cys Ala Arg Asp Phe Gly Val Gly Leu Ala Trp Tyr Ser Asp Leu Trp 1 5 10 15 <210> 6225 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6225 tgggacacgt ccatcagtac agtctacatg gagctgagca ggctgagatc tgacgacacg 60 gccgtgtatt cctgtgcgag agatttcggg gtcgggttgg cctggtactc cgatctctgg 120 ggccgtggc 129 <210> 6226 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6226 Trp Asp Thr Ser Ile Ser Thr Val Tyr Met Glu Leu Ser Arg Leu Arg 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Ser Cys Ala Arg Asp Phe Gly Val Gly 20 25 30 Leu Ala Trp Tyr Ser Asp Leu Trp Gly Arg Gly 35 40 <210> 6227 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6227 agggacacgt ccatcagtac agtctacatg gagctgagca ggctgagatc tgacgacacg 60 gccgtgtatt cctgtgcgag agatttcggg gtcgggttgg cctggtactc cgatctctgg 120 ggccgtggc 129 <210> 6228 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6228 Arg Asp Thr Ser Ile Ser Thr Val Tyr Met Glu Leu Ser Arg Leu Arg 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Ser Cys Ala Arg Asp Phe Gly Val Gly 20 25 30 Leu Ala Trp Tyr Ser Asp Leu Trp Gly Arg Gly 35 40 <210> 6229 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6229 Cys Ala Arg Arg Tyr Cys Ser Ser Thr Ser Cys Tyr Trp Ser Phe Asp 1 5 10 15 Tyr Trp <210> 6230 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6230 aagtccatca gcaccgccta cctgcagtgg agcagcctga aggcctcgga caccgccatg 60 tattactgtg cgagacggta ttgtagtagt accagctgct attggagttt tgactactgg 120 ggccaggga 129 <210> 6231 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6231 Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser 1 5 10 15 Asp Thr Ala Met Tyr Tyr Cys Ala Arg Arg Tyr Cys Ser Ser Thr Ser 20 25 30 Cys Tyr Trp Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6232 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6232 aagtccatca gcaccgccta cctgcagtgg agcagcctga aggcctcgga caccaccatg 60 tattactgtg cgagacggta ttgtagtagt accagctgct attggagttt tgactactgg 120 ggccgggga 129 <210> 6233 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6233 Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser 1 5 10 15 Asp Thr Thr Met Tyr Tyr Cys Ala Arg Arg Tyr Cys Ser Ser Thr Ser 20 25 30 Cys Tyr Trp Ser Phe Asp Tyr Trp Gly Arg Gly 35 40 <210> 6234 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6234 Cys Ala Lys Glu Phe Glu Thr Lys Ser Gly Tyr Gly Asp Tyr Trp 1 5 10 15 <210> 6235 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6235 ttcagagaca actccaagaa cacactgtat ctgcagatga acagtctgag agccgaggac 60 acggccatat attactgtgc gaaagagttc gaaaccaaaa gtggatatgg ggactactgg 120 ggccagggc 129 <210> 6236 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6236 Phe Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Lys Glu Phe Glu Thr 20 25 30 Lys Ser Gly Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 6237 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6237 tccagagaca attacaagaa cacactgtat ctgcaaatga acagcctgag agccgaggac 60 acggccatat attactgtgc gaaagagttc gaaaccaaaa gtggatatgg ggactactgg 120 ggccaggga 129 <210> 6238 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6238 Ser Arg Asp Asn Tyr Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Lys Glu Phe Glu Thr 20 25 30 Lys Ser Gly Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 6239 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6239 Cys Ala Arg Val Leu Leu Arg Tyr Ser Gly Ser Ser Phe Asp Tyr Trp 1 5 10 15 <210> 6240 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6240 gtagacacgt ccaagaacca gttctccctg aagctgagct ctgtgaccgc cgcggacacg 60 gctgtgtatt actgtgcgag agttttgttg cggtatagtg ggagctcgtt tgactactgg 120 ggccaggga 129 <210> 6241 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6241 Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Leu Leu Arg Tyr 20 25 30 Ser Gly Ser Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6242 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6242 gtagacacgt ccaagaacca gttctccctg aagctgagct ctgcgaccgc cgcggacacg 60 gctgtgtatt actgtgcgag agttttgttg cggtatagtg ggagctcgtt tgactactgg 120 ggccaggga 129 <210> 6243 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6243 Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Ala Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Leu Leu Arg Tyr 20 25 30 Ser Gly Ser Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6244 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6244 Cys Thr Thr Ala Val Thr Pro Ala Leu Asp Tyr Trp 1 5 10 <210> 6245 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6245 ttcaccatct caggagatga ttcaaaaaac acgctgtatc tgcaaatgaa cagcctgaaa 60 accgaggaca cagccgtgta ttactgtacc acagcggtga cgccagctct tgactactgg 120 ggccaggga 129 <210> 6246 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6246 Phe Thr Ile Ser Gly Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Ala 20 25 30 Val Thr Pro Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6247 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6247 ttcaccatct caagagatga ttcaaaaaac acgctgtatc tgcaaatgaa cagcctgaaa 60 accgaggaca cagccgtgta ttactgtacc acagcggtga cgccagctct tgactactgg 120 ggccaggga 129 <210> 6248 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6248 Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Ala 20 25 30 Val Thr Pro Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6249 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6249 Cys Ala His Val Arg Ser Pro Ser Met Gly Ala Phe Trp Ile Trp 1 5 10 15 <210> 6250 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6250 accaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacat atttctgtgc acacgtccgt tctccgagca tgggtgcttt ttggatctgg 120 ggccaaggg 129 <210> 6251 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6251 Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Phe Cys Ala His Val Arg Ser Pro 20 25 30 Ser Met Gly Ala Phe Trp Ile Trp Gly Gln Gly 35 40 <210> 6252 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6252 accaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacat atttctgtgc acacgtccgt tctccgagca tgggtgcctt ttggatctgg 120 ggccaaggg 129 <210> 6253 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6253 Cys Ala Arg Met Glu Ser Gly Thr Tyr Gln Asp Leu Asp Tyr Trp 1 5 10 15 <210> 6254 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6254 accagtgaca cgtccacgag cacagtctac atggagctga acagcctgat atctgaagac 60 acggccgtgt attactgtgc gagaatggag agtgggacct accaagacct tgactactgg 120 ggccaggga 129 <210> 6255 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6255 Thr Ser Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Asn Ser Leu 1 5 10 15 Ile Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Met Glu Ser Gly 20 25 30 Thr Tyr Gln Asp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6256 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6256 accagtgaca cgtccacgag cacagtctac atggagctga acagcctgag atctgaagac 60 acggccgtgt attactgtgc gagaatggag agtgggacct accaagacct tgactactgg 120 ggccaggga 129 <210> 6257 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6257 Thr Ser Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Asn Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Met Glu Ser Gly 20 25 30 Thr Tyr Gln Asp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6258 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6258 Cys Ala Arg Asp Glu Gly His Tyr Tyr Gly Ser Glu Gly Gly Tyr Tyr 1 5 10 15 Tyr Tyr Gly Met Asp Val Trp 20 <210> 6259 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6259 gcctacatgg cgctgagcag cctgagatct gaggacacgg ccgtgtatta ctgtgcgaga 60 gacgaggggc attactatgg ttcagagggg ggctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6260 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6260 Ala Tyr Met Ala Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Asp Glu Gly His Tyr Tyr Gly Ser Glu Gly Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6261 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6261 gcctacatgg agctgagcag cctgagatct gaggacacgg ccgtgtatta ctgtgcgaga 60 gacgaggggc attactatgg ttcagagggg ggctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6262 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6262 Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Asp Glu Gly His Tyr Tyr Gly Ser Glu Gly Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6263 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6263 Cys Ala Lys Asp Arg Thr Thr Leu Arg Trp Val Leu Gly Gly Met Asp 1 5 10 15 Val Trp <210> 6264 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6264 aacagcaaaa actccctgta tctgcaaatg aacagtctga gagctgagga caccgccttg 60 tattactgtg caaaagatcg gacgacctta cgttgggttc tggggggtat ggacgtctgg 120 ggccaaggg 129 <210> 6265 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6265 Asn Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Arg Thr Thr Leu Arg Trp 20 25 30 Val Leu Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6266 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6266 caacagcaaa actccctgta tctgcaaatg aacagtctga gagctgagga caccgccttg 60 tattactgtg caaaagatcg gacgacctta cgttgggttc tggggggtat ggacgtctgg 120 ggccaaggg 129 <210> 6267 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6267 Gln Gln Gln Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Arg Thr Thr Leu Arg Trp 20 25 30 Val Leu Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6268 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6268 Cys Ala Lys Glu Phe Glu Thr Lys Thr Gly Tyr Gly Asp Tyr Trp 1 5 10 15 <210> 6269 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6269 tccagagaca attccaagaa cattctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccacat attactgtgc gaaagagttc gaaaccaaaa ctggatatgg ggactactgg 120 ggccagggc 129 <210> 6270 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6270 Ser Arg Asp Asn Ser Lys Asn Ile Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Thr Tyr Tyr Cys Ala Lys Glu Phe Glu Thr 20 25 30 Lys Thr Gly Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 6271 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6271 tccagagaca attccaagaa cacactgtat ctgcaaatga acagcctgag agccgaggac 60 acggccatat attactgtgc gaaagagttc gaaaccaaaa ctggatatgg ggactactgg 120 ggccagggc 129 <210> 6272 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6272 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Lys Glu Phe Glu Thr 20 25 30 Lys Thr Gly Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 6273 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6273 Cys Ala Lys Asp Leu Tyr Ser Ser Ser Ser Gly Gly Phe Asp Tyr Trp 1 5 10 15 <210> 6274 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6274 agggacaacg ccaagaactc cctgtatctg caaatgaaca gtctgagagc tgaggacacg 60 gccttgtatt actgtgcaaa agacctgtat agcagcagct cagggggctt tgactactgg 120 ggccagggg 129 <210> 6275 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6275 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Leu Tyr Ser Ser 20 25 30 Ser Ser Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6276 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6276 agagacaacg ccaagaactc cctgtatctg caaatgaaca gtctgagagc tgaggacacg 60 gccttgtatt actgtgcaaa agacctgtat agcagcagct cagggggctt tgactactgg 120 ggccaggga 129 <210> 6277 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6277 Cys Ala Lys Ser Ile Ala Val Ala Ala Cys Phe Asp Tyr Trp 1 5 10 <210> 6278 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6278 atctccatat ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaagagt atagcagtgg ctgcctgctt tgactactgg 120 ggccaggga 129 <210> 6279 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6279 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ser Ile Ala 20 25 30 Val Ala Ala Cys Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6280 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6280 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaagagt atagcagtgg ctgcctgctt tgactactgg 120 ggccaggga 129 <210> 6281 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6281 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ser Ile Ala 20 25 30 Val Ala Ala Cys Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6282 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6282 Cys Ala Arg Ala Gly Trp Tyr Asp Glu Gly Gly Phe Asp Tyr Trp 1 5 10 15 <210> 6283 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6283 accagggaca catccgcgag cacagcctac atggagctga gcagcctgag atctgaagac 60 acggctgtgt attactgtgc gagggcgggc tggtacgacg agggaggttt tgactactgg 120 ggccaggga 129 <210> 6284 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6284 Thr Arg Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Gly Trp Tyr 20 25 30 Asp Glu Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6285 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6285 accagggaca catccgcgag cacagcctac atggagctga gcagcctgag atctgaagac 60 acgactgtgt attactgtgc gagggcgggc tggtacgacg agggaggttt tgactactgg 120 ggccaggga 129 <210> 6286 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6286 Thr Arg Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Thr Val Tyr Tyr Cys Ala Arg Ala Gly Trp Tyr 20 25 30 Asp Glu Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6287 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6287 Cys Ala Arg Ala Asp Ser Arg Lys Asp Val Ser Tyr Gly Met Asp Val 1 5 10 15 Trp <210> 6288 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6288 aacacctcca taagcacagc ctacatggag ctgagcagcc tgagatctga ggacacggcc 60 gtgtattact gtgcgagggc cgactcccga aaagacgtct cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6289 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6289 Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Asp Ser Arg Lys Asp 20 25 30 Val Ser Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6290 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6290 Cys Ala Lys Asp Ile Ala Val Ala Gly Thr Asp Leu Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 6291 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6291 aaaaactccc tgtatctgca aatgaacagt ctgagaactg aggacaccgc cttgtattac 60 tgtgcaaaag atatagcagt ggctggtacg gatttgtact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6292 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6292 Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Thr Glu Asp Thr 1 5 10 15 Ala Leu Tyr Tyr Cys Ala Lys Asp Ile Ala Val Ala Gly Thr Asp Leu 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6293 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6293 aaaactccct gtttctgcaa atgcaacagt ctgagaactg aggacaccgc cttgtattac 60 tgtgcaaaag atatagcagt ggctggtacg gatttgtact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6294 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6294 Lys Thr Pro Cys Phe Cys Lys Cys Asn Ser Leu Arg Thr Glu Asp Thr 1 5 10 15 Ala Leu Tyr Tyr Cys Ala Lys Asp Ile Ala Val Ala Gly Thr Asp Leu 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6295 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6295 Cys Ala Arg Gly Asn Arg Ile Ala Ala Ala Gly Ile Arg Ser Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 6296 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6296 acagcctaca tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agaggcaacc gtatagcagc agctggtatt cgatcctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6297 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6297 Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Asn Arg Ile Ala Ala Ala Gly Ile Arg Ser 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6298 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6298 aaagcctaca tggtgctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agaggcaacc gtatagcagc agctggtatt cgatcctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6299 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6299 Lys Ala Tyr Met Val Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Asn Arg Ile Ala Ala Ala Gly Ile Arg Ser 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6300 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6300 Cys Ala Arg Gly Ala Asn Glu Phe His Phe Trp 1 5 10 <210> 6301 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6301 cgattcacct tctccagaga cgacgccaag aactccctgt atctgcaaat gaacagtctg 60 agagccgagg acacggcctt gtattactgt gcgagggggg caaacgaatt ccatttctgg 120 ggccaaggg 129 <210> 6302 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6302 Arg Phe Thr Phe Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Arg 20 25 30 Gly Ala Asn Glu Phe His Phe Trp Gly Gln Gly 35 40 <210> 6303 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6303 cgattcacca tctccagaga caacgccaag aactccctgt atctgcaaat gaacagtctg 60 agagccgagg acacggcctt gtattactgt gcgagggggg caaacgaatt ccatttctgg 120 ggccaaggg 129 <210> 6304 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6304 Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Arg 20 25 30 Gly Ala Asn Glu Phe His Phe Trp Gly Gln Gly 35 40 <210> 6305 <211> 27 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6305 Cys Ala Lys Leu Ser Leu Ser Tyr Ser Glu Thr Met Val Arg Val His 1 5 10 15 Gly Tyr Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 6306 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6306 ttcaacagcc tgagagccga ggacacggcc gtatattact gtgcgaaact atccctgtcg 60 tattcggaga ctatggttcg ggtccatggg tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6307 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6307 Phe Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 1 5 10 15 Leu Ser Leu Ser Tyr Ser Glu Thr Met Val Arg Val His Gly Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6308 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6308 atgaacagcc tgagagccga ggacacggcc gtatattact gtgcgaaact atccctgtcg 60 tattcggaga ctatggttcg ggtccatggg tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6309 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6309 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 1 5 10 15 Leu Ser Leu Ser Tyr Ser Glu Thr Met Val Arg Val His Gly Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6310 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6310 Cys Ala Arg Ala Ala Lys Arg Gln Gln Leu Phe Pro Arg Asn Tyr Phe 1 5 10 15 Asp Tyr Trp <210> 6311 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6311 tccacgagca cagtctacat ggagctgagt agcctgagat ctgaggacac ggccgtgtat 60 tactgtgcga gagcagctaa gaggcagcag ctgtttcccc gaaactactt tgactactgg 120 ggccaggga 129 <210> 6312 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6312 Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Ala Ala Lys Arg Gln Gln Leu Phe 20 25 30 Pro Arg Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6313 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6313 tccacgagca cagtctacat ggagctgagc agcctgagat ctgaggacac ggccgtgtat 60 tactgtgcga gagcagctaa gaggcagcag ctgtttcccc gaaactactt tgactactgg 120 ggccaggga 129 <210> 6314 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6314 Cys Ala Lys Gly Ser Gly Ile Ala Val Ala Gly Thr Thr Val Gly Asn 1 5 10 15 Trp Tyr Phe Asp Leu Trp 20 <210> 6315 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6315 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaggggtcgg gtatagcagt ggctggtacc acagttggga actggtactt cgatctctgg 120 ggccgtggc 129 <210> 6316 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6316 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Gly Ser Gly Ile Ala Val Ala Gly Thr Thr Val 20 25 30 Gly Asn Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 6317 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6317 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaggggtcgg gtatagcagt ggctggtacc acagttggga actggtactt cgatctctgg 120 ggccgtggc 129 <210> 6318 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6318 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Gly Ser Gly Ile Ala Val Ala Gly Thr Thr Val 20 25 30 Gly Asn Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 6319 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6319 Cys Ala Lys Asp Thr Tyr Ser Arg Gly Trp Leu Asp Tyr Trp 1 5 10 <210> 6320 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6320 atctccagag acaacgccaa gaactccctg tatctgcaaa tgaacagtct gagaggtgag 60 gacacggcct tgtattactg tgcaaaagat acctatagtc gtggctggct ggactactgg 120 ggccaggga 129 <210> 6321 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6321 Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Gly Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Thr Tyr 20 25 30 Ser Arg Gly Trp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6322 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6322 acctccagag acaacgccaa gaactccctg tatctgcaaa tgaacagtct gggaggtgag 60 gacacggcct tgtattactg tgcaaaagat acctatagtc gtggctggct ggactactgg 120 ggccaggga 129 <210> 6323 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6323 Thr Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Gly Gly Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Thr Tyr 20 25 30 Ser Arg Gly Trp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6324 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6324 Cys Ala Arg Asn Asn Phe Tyr Asp Arg Ser Gly Tyr His Tyr Trp 1 5 10 15 <210> 6325 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6325 tccgtggaca cgtccaagaa ccaattctcc ctgaagctga gctctgtgac cgccgcggac 60 acggctcttt attactgtgc gaggaacaat ttctatgaca ggagtggtta tcactactgg 120 ggccaggga 129 <210> 6326 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6326 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Leu Tyr Tyr Cys Ala Arg Asn Asn Phe Tyr 20 25 30 Asp Arg Ser Gly Tyr His Tyr Trp Gly Gln Gly 35 40 <210> 6327 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6327 tccgtagaca cgtccaagaa ccaattctcc ctgaagctga gctctgtgac cgccgcggac 60 acggctgtat attactgtgc gaggaacaat ttctatgata ggagtggtta tcactactgg 120 ggccaggga 129 <210> 6328 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6328 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asn Asn Phe Tyr 20 25 30 Asp Arg Ser Gly Tyr His Tyr Trp Gly Gln Gly 35 40 <210> 6329 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6329 Cys Ala Arg Asp Leu Thr Pro Leu Gly Glu Leu Arg Thr Glu Asn Ala 1 5 10 15 Phe Asp Ile Trp 20 <210> 6330 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6330 acgagcacag tctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagag atctcacccc tttgggggag ctacggaccg aaaatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6331 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6331 Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Asp Leu Thr Pro Leu Gly Glu Leu Arg 20 25 30 Thr Glu Asn Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6332 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6332 acgagcacag tctacatgga gctaagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagag atctcacccc tttgggggag ctacggaccg aaaatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6333 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6333 Cys Ala His Ser Thr Tyr Tyr Tyr Gly Ser Gly Ala Leu Phe Asp Tyr 1 5 10 15 Trp <210> 6334 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6334 gacacctcca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacag cacgtattac tatggttcgg gggccctatt tgactactgg 120 ggccaggga 129 <210> 6335 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6335 Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Thr Tyr Tyr Tyr Gly 20 25 30 Ser Gly Ala Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6336 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6336 ggacacctcc aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacag cacgtattac tatggttcgg gggccctatt tgactactgg 120 ggccaggga 129 <210> 6337 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6337 Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Thr Tyr Tyr Tyr Gly 20 25 30 Ser Gly Ala Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6338 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6338 Cys Ala Arg Ala Tyr Tyr Asp Ile Leu Thr Gly Tyr Ser Asn Phe Pro 1 5 10 15 Tyr Phe Asp Tyr Trp 20 <210> 6339 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6339 tgcacagcct acttggagct gagcagcctg agatctgaag acacggctgt gtattactgt 60 gcgagggcgt attacgatat cttgactggt tattccaatt tcccatactt tgactactgg 120 ggccaggga 129 <210> 6340 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6340 Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Ala Tyr Tyr Asp Ile Leu Thr Gly Tyr Ser 20 25 30 Asn Phe Pro Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6341 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6341 agcacagcct acatggagct gagcagcctg agatctgaag acacggctgt gtattactgt 60 gcgagggcgt attacgatat cttgactggt tattccaatt tcccatactt tgactactgg 120 ggccaggga 129 <210> 6342 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6342 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Ala Tyr Tyr Asp Ile Leu Thr Gly Tyr Ser 20 25 30 Asn Phe Pro Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6343 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6343 Cys Ala Thr Lys Pro Gly Trp Phe Asp Pro Trp 1 5 10 <210> 6344 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6344 cgagtcacca tatcagtaga cacgtccaag aaccagttct ccctgaagct gagctctgtg 60 accgccgcgg acacggctgt gtattactgt gcgactaaac cagggtggtt cgacccctgg 120 ggccaggga 129 <210> 6345 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6345 Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys 1 5 10 15 Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Thr 20 25 30 Lys Pro Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6346 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6346 cgagtcacca tatcagtaga cacgtccaag aaccagttct ccctgaagct gagctctgtg 60 accgccgcgg acacggctgc gtattactgt gcgactaaac cagggtggtt cgacccctgg 120 ggccaggga 129 <210> 6347 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6347 Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys 1 5 10 15 Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Ala Tyr Tyr Cys Ala Thr 20 25 30 Lys Pro Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6348 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6348 Cys Ala Arg Gly Ser Arg Val Met Val Gln Gly Val Ile Ile Pro Ser 1 5 10 15 Tyr Tyr Tyr Gly Met Asp Val Trp 20 <210> 6349 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6349 tatcttcaaa tgaacagcct gagagccgag gacacggccg tgtattactg tgcgagaggg 60 agcagggtta tggttcaggg agttattatc ccttcctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6350 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6350 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Gly Ser Arg Val Met Val Gln Gly Val Ile Ile Pro Ser 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6351 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6351 tatattcaaa tcaacagcct gagagccgag gacacggccg tgtattactg tgcgagaggg 60 agcagggtta tggttcaggg agttattatc ccttcctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6352 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6352 Tyr Ile Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Gly Ser Arg Val Met Val Gln Gly Val Ile Ile Pro Ser 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6353 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6353 Cys Ala Lys Asp Ala Tyr Gly Ser Gly Glu Ser Pro Arg Phe Asp Tyr 1 5 10 15 Trp <210> 6354 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6354 agacaacgcc aagaactcct gtatctgcaa atgaacagtc tgagagctga ggacacggcc 60 ttgtattact gtgcaaaaga cgcatatggt tcgggggagt ccccgcgatt tgactactgg 120 ggccaggga 129 <210> 6355 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6355 Arg Gln Arg Gln Glu Leu Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Ala Tyr Gly Ser Gly 20 25 30 Glu Ser Pro Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6356 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6356 gacaacgcca agaactccct gtatctgcaa atgaacagtc tgagagctga ggacacggcc 60 ttgtattact gtgcaaaaga cgcatatggt tcgggggagt ccccgcgatt tgactactgg 120 ggccaggga 129 <210> 6357 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6357 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Ala Tyr Gly Ser Gly 20 25 30 Glu Ser Pro Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6358 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6358 Cys Ala Arg Ala Pro Pro Glu Tyr Ser Gly Tyr Gly Cys Asp Tyr Trp 1 5 10 15 <210> 6359 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6359 tgggacacgt ccacgagcac agtctacatg gaactgagca gcctgagatc tgaggacacg 60 gccgtatatt tctgtgcgag agcccctccc gaatatagtg gctacggttg tgactactgg 120 ggccaggga 129 <210> 6360 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6360 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Ala Pro Pro Glu Tyr 20 25 30 Ser Gly Tyr Gly Cys Asp Tyr Trp Gly Gln Gly 35 40 <210> 6361 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6361 agggacacgt ccacgagcac agtctacatg gaactgagca gcctgagatc tgaggacacg 60 gccgtatatt tctgtgcgag agcccctccc gaatatagtg gctacggttg tgactactgg 120 ggccaggga 129 <210> 6362 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6362 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Ala Pro Pro Glu Tyr 20 25 30 Ser Gly Tyr Gly Cys Asp Tyr Trp Gly Gln Gly 35 40 <210> 6363 <211> 26 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6363 Cys Ala Arg Pro Ser His Gly Tyr Met Val Arg Gly Val Ile Ile Pro 1 5 10 15 Pro Ser Ile Trp Tyr Tyr Phe Asp Tyr Trp 20 25 <210> 6364 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6364 gagctgagga gcctgagatc tgacgacacg gccgtgtatt actgtgcgag accctcccat 60 ggatatatgg ttcggggagt tattatcccc ccctcgatct ggtactactt tgactactgg 120 ggccaggga 129 <210> 6365 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6365 Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala 1 5 10 15 Arg Pro Ser His Gly Tyr Met Val Arg Gly Val Ile Ile Pro Pro Ser 20 25 30 Ile Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6366 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6366 gagatgaggt gcctgtgttc tgacgacacg gccgtgtatt actgtgcgag accctcccat 60 ggatatatgg ttcggggagt tattatcccc ccctcgatct ggtactactt tgactactgg 120 ggccaggga 129 <210> 6367 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6367 Glu Met Arg Cys Leu Cys Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala 1 5 10 15 Arg Pro Ser His Gly Tyr Met Val Arg Gly Val Ile Ile Pro Pro Ser 20 25 30 Ile Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6368 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6368 Cys Ala Lys Asp Met Gly Gly Ser Tyr Tyr Pro Pro Arg Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 6369 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6369 tccctgtatc tgcaaatgaa cagtctgaga gctgaggaca cggccttgta ttactgtgca 60 aaagatatgg gtgggagcta ctaccctccc cgctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6370 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6370 Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Met Gly Gly Ser Tyr Tyr Pro Pro Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6371 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6371 tacatgtatc tgcaaatgaa cagtctgaga gctgaggaca cggccttgta ttactgtgca 60 aaagatatgg gtgggagcta ctaccctccc cgctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6372 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6372 Tyr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Met Gly Gly Ser Tyr Tyr Pro Pro Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6373 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6373 Cys Ala Lys Asp Tyr Cys Gly Gly Asp Cys Tyr Leu Ser Phe Trp Tyr 1 5 10 15 Phe Asp Leu Trp 20 <210> 6374 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6374 caagaactcc ctgtatctgc aatgaacagt ctgagagctg aggacacggc cttgtattac 60 tgtgcaaaag attattgtgg tggtgactgc tatttatcat tctggtactt cgatctctgg 120 ggccgtggc 129 <210> 6375 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6375 Gln Glu Leu Pro Val Ser Ala Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Leu Tyr Tyr Cys Ala Lys Asp Tyr Cys Gly Gly Asp Cys Tyr Leu 20 25 30 Ser Phe Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 6376 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6376 aagaactccc tgtatctgca aatgaacagt ctgagagctg aggacacggc cttgtattac 60 tgtgcaaaag attattgtgg tggtgactgc tatttatcat tctggtactt cgatctctgg 120 ggccgtggc 129 <210> 6377 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6377 Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Leu Tyr Tyr Cys Ala Lys Asp Tyr Cys Gly Gly Asp Cys Tyr Leu 20 25 30 Ser Phe Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 6378 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6378 Cys Ala Lys Val Gly Val Ala Gly Thr Gly Asp Phe Trp Tyr Phe Asp 1 5 10 15 Leu Trp <210> 6379 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6379 tgttccgaga acacgctgtt tctgcaaatg aacagcctga gagtcgagga cacggccgta 60 tattactgtg cgaaagtagg cgtggctggc actggggact tctggtactt cgatctctgg 120 ggccgtggc 129 <210> 6380 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6380 Cys Ser Glu Asn Thr Leu Phe Leu Gln Met Asn Ser Leu Arg Val Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Val Ala Gly Thr Gly 20 25 30 Asp Phe Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 6381 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6381 agttccgaga acacgctgtt tctgcaaatg aacagcctga gagtcgagga cacggccgta 60 tattactgtg cgaaagtagg cgtggctggc actggggact tctggtactt cgatctctgg 120 ggccgtggc 129 <210> 6382 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6382 Ser Ser Glu Asn Thr Leu Phe Leu Gln Met Asn Ser Leu Arg Val Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Val Ala Gly Thr Gly 20 25 30 Asp Phe Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 6383 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6383 Cys Ala Arg Trp Gly Met Gln Gln Gln Leu Gly Leu Asp Tyr Trp 1 5 10 15 <210> 6384 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6384 accagggact cgtccttcag cacagcctac atggagctga gcaggctgag atctgacgac 60 acggccgtgt attactgtgc gagatgggga atgcagcagc agctgggact tgactactgg 120 ggccaggga 129 <210> 6385 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6385 Thr Arg Asp Ser Ser Phe Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu 1 5 10 15 Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Trp Gly Met Gln 20 25 30 Gln Gln Leu Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6386 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6386 accagggaca cgtccatcag cacagcctac atggagctga gcaggctgag atctgacgac 60 acggccgtgt attactgtgc gagatgggga atgcagcagc agctgggact tgactactgg 120 ggccaggga 129 <210> 6387 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6387 Thr Arg Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu 1 5 10 15 Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Trp Gly Met Gln 20 25 30 Gln Gln Leu Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6388 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6388 Cys Ala Arg Lys Val Ala Ser Ser Gly Phe Gly Glu Leu Phe Phe Asp 1 5 10 15 Tyr Trp <210> 6389 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6389 aattccaagg acacgctgta tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgagaaaagt cgcctcttcg gggttcgggg agttattttt tgactactgg 120 ggccaggga 129 <210> 6390 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6390 Asn Ser Lys Asp Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Lys Val Ala Ser Ser Gly Phe 20 25 30 Gly Glu Leu Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6391 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6391 aattccaaga acacgctgta tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgagaaaagt cgcctcttcg gggttcgggg agttattttt tgactactgg 120 ggccaggga 129 <210> 6392 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6392 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Lys Val Ala Ser Ser Gly Phe 20 25 30 Gly Glu Leu Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6393 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6393 Cys Ala Arg Gly Phe Trp Ile Ala Thr Ala Gly Ile Asn Trp Phe Asp 1 5 10 15 Pro Trp <210> 6394 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6394 acgtccaaga accagttctc cctgaagctg agctctgtga ccgccgcgga cacggccgtg 60 tatcactgtg cgagaggttt ttggatagca acagctggta tcaattggtt cgacccctgg 120 ggccaggga 129 <210> 6395 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6395 Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Thr Ala Val Tyr His Cys Ala Arg Gly Phe Trp Ile Ala Thr Ala 20 25 30 Gly Ile Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6396 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6396 acgtccaaga accagttctc cctgaagccg agctctgtga ccgccgcgga cacggccgtg 60 tatcactgtg cgagaggttt ttggatagca acagctggta tcaattggtt cgacccctgg 120 ggccaggga 129 <210> 6397 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6397 Thr Ser Lys Asn Gln Phe Ser Leu Lys Pro Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Thr Ala Val Tyr His Cys Ala Arg Gly Phe Trp Ile Ala Thr Ala 20 25 30 Gly Ile Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6398 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6398 Cys Ala Ser Thr Lys Phe Tyr Cys Thr Gly Gly Val Cys Ser Leu Asp 1 5 10 15 Tyr Trp <210> 6399 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6399 acatccacga gcacagccta catggaactg aagggcctga gatctgacga ctcggccgtc 60 tattattgtg caagtaccaa gttctattgt actggtggtg tatgctccct tgactactgg 120 ggccaggga 129 <210> 6400 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6400 Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Lys Gly Leu Arg Ser Asp 1 5 10 15 Asp Ser Ala Val Tyr Tyr Cys Ala Ser Thr Lys Phe Tyr Cys Thr Gly 20 25 30 Gly Val Cys Ser Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6401 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6401 acatccacga gcacaaccta catggaactg atgagcctga gatctgacga ctcggccgtg 60 tattactgtg caagtaccaa gttctattgt actggtggtg tttgctccct tgactactgg 120 ggccaggga 129 <210> 6402 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6402 Thr Ser Thr Ser Thr Thr Tyr Met Glu Leu Met Ser Leu Arg Ser Asp 1 5 10 15 Asp Ser Ala Val Tyr Tyr Cys Ala Ser Thr Lys Phe Tyr Cys Thr Gly 20 25 30 Gly Val Cys Ser Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6403 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6403 Cys Ala Arg Glu Asn Ser Gly Tyr Glu Phe Asp Tyr Trp 1 5 10 <210> 6404 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6404 accatctcca gggacaacgc caagaactca ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gaaaatagtg gctacgagtt tgactactgg 120 ggccaggga 129 <210> 6405 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6405 Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Asn 20 25 30 Ser Gly Tyr Glu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6406 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6406 accatctcca ggcacaaccc caagaactca ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gaaaatagtg gctacgagtt tgactactgg 120 ggccaggga 129 <210> 6407 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6407 Thr Ile Ser Arg His Asn Pro Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Asn 20 25 30 Ser Gly Tyr Glu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6408 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6408 Cys Ala Lys Ser Arg Gly Val Asp Tyr Trp 1 5 10 <210> 6409 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6409 ggccggttca ccatctccag agacaattcc aagaacacgc tgtatctgca aatgaacagc 60 ctgagagccg aggacacggc cgtatattac tgtgcgaaaa gccggggtgt tgactactgg 120 ggccaggga 129 <210> 6410 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6410 Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu 1 5 10 15 Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Lys Ser Arg Gly Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 6411 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6411 ggcaggttca ccatctccag acacaattcc aagaactcgc tgtatctgca aattaacagc 60 ctgagagccg aggacacggc cgtatattac tgtgcgaaaa gccggggtgt tgactactgg 120 ggccaggga 129 <210> 6412 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6412 Gly Arg Phe Thr Ile Ser Arg His Asn Ser Lys Asn Ser Leu Tyr Leu 1 5 10 15 Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Lys Ser Arg Gly Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 6413 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6413 Cys Ala Arg Asp Ser Gly Tyr Ser Asn Tyr Pro Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 6414 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6414 tgggacaacg ccaacaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgcgag agattccgga tacagtaact acccctactt tgactactgg 120 ggccaggga 129 <210> 6415 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6415 Trp Asp Asn Ala Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ser Gly Tyr Ser 20 25 30 Asn Tyr Pro Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6416 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6416 agggacaacg ccaagaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgcgag agattccgga tacagtaact acccctactt tgactactgg 120 ggccaggga 129 <210> 6417 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6417 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ser Gly Tyr Ser 20 25 30 Asn Tyr Pro Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6418 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6418 Cys Ala Arg Pro Gly Gly Arg Ile Val Gly Ala Leu Trp Gly Ala Phe 1 5 10 15 Asp Tyr Trp <210> 6419 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6419 tccatcagcg ccgcctacct gcagtggagc agcctgaagg cctcggacac cgccatgtat 60 tactgcgcga gacccggcgg taggatagtg ggagctctct ggggggcttt tgactactgg 120 ggccaggga 129 <210> 6420 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6420 Ser Ile Ser Ala Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser Asp 1 5 10 15 Thr Ala Met Tyr Tyr Cys Ala Arg Pro Gly Gly Arg Ile Val Gly Ala 20 25 30 Leu Trp Gly Ala Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6421 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6421 tccatcagca ccgcctacct gcagtggagc agcctgaagg cctcggacac cgccatgtat 60 tactgtgcga gacccggcgg taggatagtg ggagctctct ggggggcttt tgactactgg 120 ggccaggga 129 <210> 6422 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6422 Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser Asp 1 5 10 15 Thr Ala Met Tyr Tyr Cys Ala Arg Pro Gly Gly Arg Ile Val Gly Ala 20 25 30 Leu Trp Gly Ala Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6423 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6423 Cys Ala Arg Glu Val Tyr Ser Gly Gly Trp His Val Gly Val Gly Asp 1 5 10 15 Tyr Trp <210> 6424 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6424 accgctgtcg gcacggcata tctgcagatc agcagcctaa aggctgagga cactgccgtg 60 tattattgtg cgagagaagt gtatagcggt ggctggcacg tgggggtcgg ggactactgg 120 ggccaggga 129 <210> 6425 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6425 Thr Ala Val Gly Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Val Tyr Ser Gly Gly Trp 20 25 30 His Val Gly Val Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 6426 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6426 accgctgtcg gcacggcata tctgcagatc agcagcctaa aggctgagga cactgccatg 60 tattattgtg cgagagaagt gtatagcggt ggctggcacg tgggggtcgg ggactactgg 120 ggccagggg 129 <210> 6427 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6427 Thr Ala Val Gly Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu 1 5 10 15 Asp Thr Ala Met Tyr Tyr Cys Ala Arg Glu Val Tyr Ser Gly Gly Trp 20 25 30 His Val Gly Val Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 6428 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6428 Cys Ala Arg Asp Arg Arg Phe Leu Glu Trp Leu Lys Ala Asn Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 6429 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6429 tgcacagcct acttggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagatc ggcgattttt ggagtggtta aaagcgaact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6430 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6430 Cys Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Arg Arg Phe Leu Glu Trp Leu Lys Ala 20 25 30 Asn Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6431 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6431 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagatc ggcgattttt ggagtggtta aaagcgaact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6432 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6432 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Arg Arg Phe Leu Glu Trp Leu Lys Ala 20 25 30 Asn Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6433 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6433 Cys Ala Arg Gly Pro Glu Trp Leu His Tyr Leu Asp Tyr Trp 1 5 10 <210> 6434 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6434 ttatcaatag acaggcccaa gaaccagttc tccctgaacc tgagctctgt gaccgctgcg 60 gacacggccg tgtattactg tgcgagaggc ccggagtggc ttcattactt ggactactgg 120 ggccaggga 129 <210> 6435 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6435 Leu Ser Ile Asp Arg Pro Lys Asn Gln Phe Ser Leu Asn Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Pro Glu 20 25 30 Trp Leu His Tyr Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6436 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6436 atatcaatag acaggtccaa gaaccagttc tccctgaacc tgagctctgt gaccgctgcg 60 gacacggccg tgtattactg tgcgagaggc ccggagtggc ttcattactt ggactactgg 120 ggccaggga 129 <210> 6437 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6437 Ile Ser Ile Asp Arg Ser Lys Asn Gln Phe Ser Leu Asn Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Pro Glu 20 25 30 Trp Leu His Tyr Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6438 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6438 Cys Ala Arg Gly Ser Ser Asp Glu Ala Thr Tyr Tyr Tyr Gly Pro Asp 1 5 10 15 Asp Ala Phe Asp Ile Trp 20 <210> 6439 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6439 acagcctact tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agaggatcat ccgacgaagc gacgtattac tatggtcccg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6440 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6440 Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Ser Ser Asp Glu Ala Thr Tyr Tyr Tyr Gly 20 25 30 Pro Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6441 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6441 acagcctaca tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agaggatcat ccgacgaagc gacgtattac tatggtcccg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6442 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6442 Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Ser Ser Asp Glu Ala Thr Tyr Tyr Tyr Gly 20 25 30 Pro Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6443 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6443 Cys Ala Arg Asp Arg Thr Gly Leu Gly Leu Asp Ile Trp 1 5 10 <210> 6444 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6444 accacttccg tagacaggtc caagaaccag ttctccctga aggtgaactc tgtgaccgcc 60 gcagacacgg ccgtgtatta ctgtgcgaga gacaggactg gtttagggct tgatatctgg 120 ggccaaggg 129 <210> 6445 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6445 Thr Thr Ser Val Asp Arg Ser Lys Asn Gln Phe Ser Leu Lys Val Asn 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg 20 25 30 Thr Gly Leu Gly Leu Asp Ile Trp Gly Gln Gly 35 40 <210> 6446 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6446 accacatccg tagacaggtc caagaacctg ttctccctga aggtgaactc tgtgaccgcc 60 gcagacacgg ccgtgtatta ctgtgcgaga gacaggactg gtttagggct tgatatctgg 120 ggccaaggg 129 <210> 6447 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6447 Thr Thr Ser Val Asp Arg Ser Lys Asn Leu Phe Ser Leu Lys Val Asn 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg 20 25 30 Thr Gly Leu Gly Leu Asp Ile Trp Gly Gln Gly 35 40 <210> 6448 <211> 9 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6448 Cys Ala Arg Asp Gly Trp Ala Cys Trp 1 5 <210> 6449 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6449 aaaagtctaa taagcatcaa cgcagacaca tccaagaacc agttctccct gcacttaaac 60 tttgtgactc ccgaggacac ggctgtgtat tactgtgcaa gagatggctg ggcctgctgg 120 ggccaggga 129 <210> 6450 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6450 Lys Ser Leu Ile Ser Ile Asn Ala Asp Thr Ser Lys Asn Gln Phe Ser 1 5 10 15 Leu His Leu Asn Phe Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys 20 25 30 Ala Arg Asp Gly Trp Ala Cys Trp Gly Gln Gly 35 40 <210> 6451 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6451 aaaagtcgaa taagcatcaa cgcagacaca tccaagaacc agttctccct gcacttgaac 60 tttgtgactc ccgaggacac ggctgtgtat tactgtgcaa gagatggctg ggcctgctgg 120 ggccaggga 129 <210> 6452 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6452 Lys Ser Arg Ile Ser Ile Asn Ala Asp Thr Ser Lys Asn Gln Phe Ser 1 5 10 15 Leu His Leu Asn Phe Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys 20 25 30 Ala Arg Asp Gly Trp Ala Cys Trp Gly Gln Gly 35 40 <210> 6453 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6453 Cys Ala Arg Ala Met Ser Ile Ala Ala Arg Arg Gly Val Gly Tyr Trp 1 5 10 15 <210> 6454 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6454 tgggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agctatgagt atagcagctc ggcggggcgt tgggtactgg 120 ggccaggga 129 <210> 6455 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6455 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Met Ser Ile Ala 20 25 30 Ala Arg Arg Gly Val Gly Tyr Trp Gly Gln Gly 35 40 <210> 6456 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6456 agggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agctatgagt atagcagctc ggcggggcgt tgggtactgg 120 ggccaggga 129 <210> 6457 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6457 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Met Ser Ile Ala 20 25 30 Ala Arg Arg Gly Val Gly Tyr Trp Gly Gln Gly 35 40 <210> 6458 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6458 Cys Ala His Tyr His Gly Asp Tyr Asp Thr Trp 1 5 10 <210> 6459 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6459 caggctcacc atcaccaagg acacctccaa aaccaggtgg tccttacaat gaccaacatg 60 gaccctgtgg acacagccac atattactgt gcacactacc acggtgacta cgacacctgg 120 ggccaggga 129 <210> 6460 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6460 Gln Ala His His His Gln Gly His Leu Gln Asn Gln Val Val Leu Thr 1 5 10 15 Met Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His 20 25 30 Tyr His Gly Asp Tyr Asp Thr Trp Gly Gln Gly 35 40 <210> 6461 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6461 aggctcacca tcaccaagga cacctccaaa aaccaggtgg tccttacaat gaccaacatg 60 gaccctgtgg acacagccac atattactgt gcacactacc acggtgacta cgacacctgg 120 ggccaggga 129 <210> 6462 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6462 Arg Leu Thr Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr 1 5 10 15 Met Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His 20 25 30 Tyr His Gly Asp Tyr Asp Thr Trp Gly Gln Gly 35 40 <210> 6463 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6463 Cys Ala Arg Gly Asp Ser Ser Ser Trp Phe Val Asp Tyr Trp 1 5 10 <210> 6464 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6464 ttgaccaggg acacgtccac gagcacagtc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagaggg gacagcagca gctggtttgt ggactactgg 120 ggccaggga 129 <210> 6465 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6465 Leu Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp Ser 20 25 30 Ser Ser Trp Phe Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 6466 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6466 atgaccaggg acacgtccac gagcacagtc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagaggg gacagcagca gctggtttgt ggactactgg 120 ggccaggga 129 <210> 6467 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6467 Met Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp Ser 20 25 30 Ser Ser Trp Phe Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 6468 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6468 Cys Ala His Arg Arg Asn Leu Asp Tyr Phe Asp Gly Ser Gly Arg Tyr 1 5 10 15 Asn Tyr Phe Gly Pro Trp 20 <210> 6469 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6469 caggtggtcc taacaatgac caacgtggac cctgtggaca cagccaccta ttactgtgca 60 cacagacgta atctggatta ctttgatggt agtggtcgct acaactactt cggcccctgg 120 ggccaggga 129 <210> 6470 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6470 Gln Val Val Leu Thr Met Thr Asn Val Asp Pro Val Asp Thr Ala Thr 1 5 10 15 Tyr Tyr Cys Ala His Arg Arg Asn Leu Asp Tyr Phe Asp Gly Ser Gly 20 25 30 Arg Tyr Asn Tyr Phe Gly Pro Trp Gly Gln Gly 35 40 <210> 6471 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6471 ccaggtggtc ctacaatgac caacgtggac cctgtggaca cagccaccta ttactgtgca 60 cacagacgta atctggatta ctttgatggt agtggtcgct acaactactt cggcccctgg 120 ggccaggga 129 <210> 6472 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6472 Pro Gly Gly Pro Thr Met Thr Asn Val Asp Pro Val Asp Thr Ala Thr 1 5 10 15 Tyr Tyr Cys Ala His Arg Arg Asn Leu Asp Tyr Phe Asp Gly Ser Gly 20 25 30 Arg Tyr Asn Tyr Phe Gly Pro Trp Gly Gln Gly 35 40 <210> 6473 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6473 Cys Thr Thr Glu Gly Ser Gly Trp Tyr Leu Phe Tyr Trp 1 5 10 <210> 6474 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6474 accatctcaa gagatgattc aaaagacacg ctgtatctgc aaatgaacag cctgaaaacc 60 gaggacacag ccgtgtatta ttgtaccaca gagggcagtg gctggtattt gttctactgg 120 ggccaggga 129 <210> 6475 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6475 Thr Ile Ser Arg Asp Asp Ser Lys Asp Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Glu Gly 20 25 30 Ser Gly Trp Tyr Leu Phe Tyr Trp Gly Gln Gly 35 40 <210> 6476 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6476 accatctcaa gagatgattc aaaaaacacg ctgtatctgc aaatgaacag cctgaaaacc 60 gaggacacag ccgtgtatta ttgtaccaca gagggcagtg gctggtattt gttctactgg 120 ggccaggga 129 <210> 6477 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6477 Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Glu Gly 20 25 30 Ser Gly Trp Tyr Leu Phe Tyr Trp Gly Gln Gly 35 40 <210> 6478 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6478 Cys Ala Arg Arg Lys Val Gly Gly Gly Tyr Trp Tyr Phe Asp Leu Trp 1 5 10 15 <210> 6479 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6479 tgggacaacg ccaagaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgcgag acggaaggtt ggcgggggtt actggtactt cgatctctgg 120 ggccgtggc 129 <210> 6480 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6480 Trp Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Arg Lys Val Gly Gly 20 25 30 Gly Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 6481 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6481 agggacaacg ccaagaactc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgcgag acggaaggtt ggcgggggtt actggtactt cgatctctgg 120 ggccgtggc 129 <210> 6482 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6482 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Arg Lys Val Gly Gly 20 25 30 Gly Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 6483 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6483 Cys Ala His Arg Gln Gly Ala Ala Ala Val Val Gly Trp Phe Asp Pro 1 5 10 15 Trp <210> 6484 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6484 gacacctcca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacag acaaggagca gcagctgttg ttggctggtt cgacccctgg 120 ggccaggga 129 <210> 6485 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6485 Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Gln Gly Ala Ala Ala 20 25 30 Val Val Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6486 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6486 ggacacctcc aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacag acaaggagca gcagctgttg ttggctggtt cgacccctgg 120 ggccaggga 129 <210> 6487 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6487 Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Gln Gly Ala Ala Ala 20 25 30 Val Val Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6488 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6488 Cys Ala Arg Gly His Gln Ser Gly Tyr Asn Tyr Tyr Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 6489 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6489 aaccagttct ccctgaagct gagctttgtg accgccgcgg acacggctgt gtattactgt 60 gcgagagggc atcaaagtgg ctacaactac tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6490 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6490 Asn Gln Phe Ser Leu Lys Leu Ser Phe Val Thr Ala Ala Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly His Gln Ser Gly Tyr Asn Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6491 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6491 aaccagttct ccctgaagct gagctctgtg accgccgcgg acacggctgt gtattactgt 60 gcgagagggc atcaaagtgg ctacaactac tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6492 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6492 Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly His Gln Ser Gly Tyr Asn Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6493 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6493 Cys Ala Arg Leu Arg Tyr Cys Ser Ser Ile Thr Ser Cys Ser Tyr Tyr 1 5 10 15 Cys Asp Tyr Trp 20 <210> 6494 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6494 atcagcaccg cctacctgca gtggagcagc ctgaaggcct tggacaccgc catgtattac 60 tgtgcgagac tcagatattg tagtagtatt actagctgct cctactactg tgactactgg 120 ggccaggga 129 <210> 6495 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6495 Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Leu Asp Thr 1 5 10 15 Ala Met Tyr Tyr Cys Ala Arg Leu Arg Tyr Cys Ser Ser Ile Thr Ser 20 25 30 Cys Ser Tyr Tyr Cys Asp Tyr Trp Gly Gln Gly 35 40 <210> 6496 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6496 atcagcaccg cctacctgca gtggagcagc ctgaaggcct cggacaccgc catgtattac 60 tgtgcgagac tcagatattg tagtagtatt actagctgct cctactactg tgactactgg 120 ggccaggga 129 <210> 6497 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6497 Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser Asp Thr 1 5 10 15 Ala Met Tyr Tyr Cys Ala Arg Leu Arg Tyr Cys Ser Ser Ile Thr Ser 20 25 30 Cys Ser Tyr Tyr Cys Asp Tyr Trp Gly Gln Gly 35 40 <210> 6498 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6498 Cys Ala Ala Asp Ser Pro Lys Gly Ser Ile Thr Gly Thr Arg Trp Tyr 1 5 10 15 Tyr Tyr Tyr Gly Met Asp Val Trp 20 <210> 6499 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6499 tacttggagc tgagctgcct gagatccgag gacacggccg tgtattactg tgcggcagat 60 tcaccaaagg ggagtataac tggaactcgg tggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6500 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6500 Tyr Leu Glu Leu Ser Cys Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Ala Asp Ser Pro Lys Gly Ser Ile Thr Gly Thr Arg Trp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6501 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6501 tacatggagc tgagcagcct gagatccgag gacacggccg tgtattactg tgcggcagat 60 tcaccaaagg ggagtataac tggaactcgg tggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6502 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6502 Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Ala Asp Ser Pro Lys Gly Ser Ile Thr Gly Thr Arg Trp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6503 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6503 Cys Ala Lys Asp Arg Trp Ile Ala Ala Ala Gly Asp Trp 1 5 10 <210> 6504 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6504 accatctcca gagacaattc caagaacacc ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccctatatta ctgtgcgaaa gatagatgga tagcggcagc tggtgactgg 120 ggccaggga 129 <210> 6505 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6505 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Arg 20 25 30 Trp Ile Ala Ala Ala Gly Asp Trp Gly Gln Gly 35 40 <210> 6506 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6506 accatctcca gagacaattc caagaacacc ctgtatccgc aaatgaacag cctgagagcc 60 gaggacacgg ccctatatta ctgtgcgaaa gatagatgga tagcggcagc tggtgactgg 120 ggccaggga 129 <210> 6507 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6507 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Pro Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Arg 20 25 30 Trp Ile Ala Ala Ala Gly Asp Trp Gly Gln Gly 35 40 <210> 6508 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6508 Cys Ala Arg Val Ile Ala Ala Ala Gly Asn Pro Phe Asp Tyr Trp 1 5 10 15 <210> 6509 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6509 accacagaca catccacgac cacagcctac atggagttga ggagcctgag atctgacgac 60 acggccgtgt attactgtgc gagagtcata gcagcagctg gcaatccctt tgactactgg 120 ggccaggga 129 <210> 6510 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6510 Thr Thr Asp Thr Ser Thr Thr Thr Ala Tyr Met Glu Leu Arg Ser Leu 1 5 10 15 Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Ile Ala Ala 20 25 30 Ala Gly Asn Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6511 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6511 accacacaca catccacgac cacagcctac atggagttga ggagcctgag atctgacgac 60 acggccgtgt attactgtgc gagagtcata gcagcagctg gcaatccctt tgactactgg 120 ggccaggga 129 <210> 6512 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6512 Thr Thr His Thr Ser Thr Thr Thr Ala Tyr Met Glu Leu Arg Ser Leu 1 5 10 15 Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Ile Ala Ala 20 25 30 Ala Gly Asn Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6513 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6513 Cys Ala Gly Ser Ser Gly Trp Arg Trp Tyr Phe Asp Tyr Trp 1 5 10 <210> 6514 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6514 atctccagag acaacgccaa gaactccctg tatctgcaaa tgaacagtct gagagctgag 60 gacacggcct tgtattactg tgcgggtagt agtggttgga ggtggtactt tgactactgg 120 ggccaggga 129 <210> 6515 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6515 Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Gly Ser Ser Gly 20 25 30 Trp Arg Trp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6516 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6516 atctccagag acaacgccaa gaactccctg tatctgcaaa tgaacagtct gagagctgag 60 gacacggcct tgtattactg tgcgggcagt agtggttgga ggtggtactt tgactactgg 120 ggccaggga 129 <210> 6517 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6517 Cys Ala Arg Gly Asn Asp Trp Tyr Ser Ser Ser Trp Tyr Leu Leu Asp 1 5 10 15 Tyr Trp <210> 6518 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6518 tcgtctaaga acctgttctc cctgaagctg agctctgtga ctgccgcgga cacggccgtg 60 tattactgtg cgagaggaaa cgactggtat agcagcagct ggtacttgct tgactactgg 120 ggccaggga 129 <210> 6519 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6519 Ser Ser Lys Asn Leu Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asn Asp Trp Tyr Ser Ser 20 25 30 Ser Trp Tyr Leu Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6520 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6520 acgtctaaga accagttctc cctgaagctg agctctgtga ctgccgcgga cacggccgtg 60 tattactgtg cgagaggaaa cgactggtat agcagcagct ggtacttgct tgactactgg 120 ggccaggga 129 <210> 6521 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6521 Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asn Asp Trp Tyr Ser Ser 20 25 30 Ser Trp Tyr Leu Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6522 <211> 29 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6522 Cys Ala Lys Asp Leu Arg Glu Glu Ser Glu Tyr Asp Tyr Val Trp Gly 1 5 10 15 Ser Tyr Arg Ala Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 6523 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6523 tgcctgagag ccgaggacac ggccgtatat tactgtgcga aagatctacg tgaagagtcc 60 gaatatgatt acgtttgggg gagttatcgt gcttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6524 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6524 Cys Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu 1 5 10 15 Arg Glu Glu Ser Glu Tyr Asp Tyr Val Trp Gly Ser Tyr Arg Ala Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6525 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6525 agcctgagag ccgaggacac ggccgtatat tactgtgcga aagatctacg tgaagagtcc 60 gaatatgatt acgtttgggg gagttatcgt gcttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6526 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6526 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu 1 5 10 15 Arg Glu Glu Ser Glu Tyr Asp Tyr Val Trp Gly Ser Tyr Arg Ala Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6527 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6527 Cys Ala Lys Leu Trp Gly Gly Gly Tyr Tyr His Ala Phe Asp Ile Trp 1 5 10 15 <210> 6528 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6528 atatataatt ccaagaacac actgtatctg caaatgaaca gtctgagagc cgaggacacg 60 gccgtatatt attgtgcgaa actgtggggt gggggctatt accatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6529 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6529 Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Leu Trp Gly Gly Gly 20 25 30 Tyr Tyr His Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6530 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6530 agagataatt ccaagaacac actgtatctg caaatgaaca gtctgagagc cgaggacacg 60 gccgtatatt attgtgcgaa actgtggggt gggggctatt accatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6531 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6531 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Leu Trp Gly Gly Gly 20 25 30 Tyr Tyr His Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6532 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6532 Cys Ala Arg Gly Gly Gly Ser Tyr Tyr Ser Asp Phe Asp Tyr Trp 1 5 10 15 <210> 6533 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6533 tcagttgaca cgtctaagaa ccagttctcc ctgaagctga gctctgtgac tgccgcggac 60 acggccgtgt attactgtgc gagaggagga gggagttatt attcggactt tgactactgg 120 ggccaggga 129 <210> 6534 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6534 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Gly Ser 20 25 30 Tyr Tyr Ser Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6535 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6535 tatgttgaca cgtctaagaa ccagttctcc ctgaagctga gctctgtgac tgccgcggac 60 acggccgtgt attactgtgc gagaggagga gggagttatt attcggactt tgactactgg 120 ggccaggga 129 <210> 6536 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6536 Tyr Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Gly Ser 20 25 30 Tyr Tyr Ser Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6537 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6537 Cys Ala Arg Leu Leu Ile Pro Met Tyr Tyr Tyr Gly Ser Gly Ser Tyr 1 5 10 15 Tyr Asn His Asn Trp Phe Asp Pro Trp 20 25 <210> 6538 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6538 ttggagctga gcaggctgag atctgacgac acggccgtgt attactgtgc gaggctcctg 60 ataccgatgt attactatgg ttcggggagt tattataacc acaactggtt cgacccctgg 120 ggccaggga 129 <210> 6539 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6539 Leu Glu Leu Ser Arg Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Leu Leu Ile Pro Met Tyr Tyr Tyr Gly Ser Gly Ser Tyr Tyr 20 25 30 Asn His Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6540 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6540 atggagctga gcaggctgag atctgacgac acggccgtgt attactgtgc gaggctcctg 60 ataccgatgt attactatgg ttcggggagt tattataacc acaactggtt cgacccctgg 120 ggccaggga 129 <210> 6541 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6541 Met Glu Leu Ser Arg Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Leu Leu Ile Pro Met Tyr Tyr Tyr Gly Ser Gly Ser Tyr Tyr 20 25 30 Asn His Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6542 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6542 Cys Ala Arg Val Gly Ile Val Val Leu Ile Thr Gly Val Cys Tyr Phe 1 5 10 15 Asp Tyr Trp <210> 6543 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6543 tccaagagca cgctgtatct tcaaatgaac agcctgagag ccgaggacac ggccgtgtat 60 tactgtgcga gagttggaat agtagtgctt attacggggg tatgctactt tgactactgg 120 ggccaggga 129 <210> 6544 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6544 Ser Lys Ser Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly Ile Val Val Leu Ile Thr 20 25 30 Gly Val Cys Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6545 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6545 tccaagaaca cgctgtatct tcaaatgaac agcctgagag ccgaggacac ggccgtgtat 60 tactgtgcga gagttggaat agtagtgctt attacggggg tatgctactt tgactactgg 120 ggccaggga 129 <210> 6546 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6546 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Val Gly Ile Val Val Leu Ile Thr 20 25 30 Gly Val Cys Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6547 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6547 Cys Ala Arg Ala Glu Ile Val Gly Ala Thr Asp His Phe Asp Tyr Trp 1 5 10 15 <210> 6548 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6548 tgggacacat ccgcgagcac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 gctgtgtatt actgtgcgag agctgagata gtgggagcta ccgatcactt tgactactgg 120 ggccaggga 129 <210> 6549 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6549 Trp Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Glu Ile Val Gly 20 25 30 Ala Thr Asp His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6550 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6550 agggacacat ccgcgagcac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 gctgtgtatt actgtgcgag agctgagata gtgggagcta ccgatcactt tgactactgg 120 ggccaggga 129 <210> 6551 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6551 Arg Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Glu Ile Val Gly 20 25 30 Ala Thr Asp His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6552 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6552 Cys Ala Lys Val Val Gly Gly Gly Asp Cys Ser Gly Gly Ser Cys Tyr 1 5 10 15 Gly Trp Tyr Phe Asp Leu Trp 20 <210> 6553 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6553 ctgtatctgc aaatgagcag tctgagagct gaggacacgg ccttgtatta ctgtgcaaaa 60 gttgtgggcg gaggagattg tagtggtggt agctgctacg gttggtactt cgatctctgg 120 ggccgtggc 129 <210> 6554 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6554 Leu Tyr Leu Gln Met Ser Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr 1 5 10 15 Tyr Cys Ala Lys Val Val Gly Gly Gly Asp Cys Ser Gly Gly Ser Cys 20 25 30 Tyr Gly Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 6555 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6555 ctgtatctgc aaatgaacag tctgagagct gaggacacgg ccttgtatta ctgtgcaaaa 60 gttgtgggcg gaggagattg tagtggtggt agctgctacg gttggtactt cgatctctgg 120 ggccgtggc 129 <210> 6556 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6556 Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr 1 5 10 15 Tyr Cys Ala Lys Val Val Gly Gly Gly Asp Cys Ser Gly Gly Ser Cys 20 25 30 Tyr Gly Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 6557 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6557 Cys Ala His Ser Arg Gly Val Trp Glu Leu Pro Asp Phe Asp Tyr Trp 1 5 10 15 <210> 6558 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6558 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagccggggg gtgtgggagc tacccgactt tgactactgg 120 ggccaggga 129 <210> 6559 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6559 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Arg Gly Val Trp 20 25 30 Glu Leu Pro Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6560 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6560 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagccggggg gtgtgggagc tacccgactt tgactactgg 120 ggccaggga 129 <210> 6561 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6561 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Arg Gly Val Trp 20 25 30 Glu Leu Pro Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6562 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6562 Cys Ala Lys Glu Gly Pro Val Arg Gly Val Pro Thr Glu Phe Asp Pro 1 5 10 15 Trp <210> 6563 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6563 tataattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga agggccggtt cggggagttc cgaccgagtt cgacccctgg 120 ggccaggga 129 <210> 6564 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6564 Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Gly Pro Val Arg Gly 20 25 30 Val Pro Thr Glu Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6565 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6565 gataattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga agggccggtt cggggagttc cgaccgagtt cgacccctgg 120 ggccaggga 129 <210> 6566 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6566 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Gly Pro Val Arg Gly 20 25 30 Val Pro Thr Glu Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6567 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6567 Cys Ala Arg Asp Tyr Tyr Tyr Asp Ser Ser Gly Gln Glu Asn Arg Leu 1 5 10 15 Trp Phe Asp Pro Trp 20 <210> 6568 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6568 tgcacagtct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatt actactatga tagtagtggt caggaaaatc gactgtggtt cgacccctgg 120 ggccaggga 129 <210> 6569 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6569 Cys Thr Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Tyr Tyr Tyr Asp Ser Ser Gly Gln Glu 20 25 30 Asn Arg Leu Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6570 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6570 agcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatt actactatga tagtagtggt caggaaaatc gactgtggtt cgacccctgg 120 ggccaggga 129 <210> 6571 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6571 Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Tyr Tyr Tyr Asp Ser Ser Gly Gln Glu 20 25 30 Asn Arg Leu Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6572 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6572 Cys Gly Arg His Glu Trp Leu Gly Leu Phe Asp His Trp 1 5 10 <210> 6573 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6573 tacatatcca tagacacgtc caagaatcag ttctccctga agctgagctc tgtgaccgcc 60 gcagacacgg ctgtgtatta ctgtgggaga catgagtggc tgggactttt tgaccactgg 120 ggccaggga 129 <210> 6574 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6574 Tyr Ile Ser Ile Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Gly Arg His Glu 20 25 30 Trp Leu Gly Leu Phe Asp His Trp Gly Gln Gly 35 40 <210> 6575 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6575 accatatcca tagacacgtc caagaatcag ttctccctga agctgagctc tgtgaccgcc 60 gcagacacgg ctgtgtatta ctgtgggaga catgagtggc tgggactttt tgaccactgg 120 ggccaggga 129 <210> 6576 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6576 Thr Ile Ser Ile Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Gly Arg His Glu 20 25 30 Trp Leu Gly Leu Phe Asp His Trp Gly Gln Gly 35 40 <210> 6577 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6577 Cys Thr Thr Val Glu Gln Trp Leu Leu Arg Gly Val Glu Tyr Trp 1 5 10 15 <210> 6578 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6578 tcaagagatg attcaaaaaa cacactgtat ctgcaaatga acagcctgaa aagtgaggac 60 acagccgtgt attactgtac cactgtagag cagtggctgc taagaggtgt ggaatactgg 120 ggccaggga 129 <210> 6579 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6579 Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Ser Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Val Glu Gln Trp 20 25 30 Leu Leu Arg Gly Val Glu Tyr Trp Gly Gln Gly 35 40 <210> 6580 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6580 tcaagagatg attcaaaaaa cacactgtat ctgcaaatga acagcctgaa aagtgaggac 60 acagccgtgc attactgtac cactgtagag cagtggctgc taagaggtgt ggaatactgg 120 ggccaggga 129 <210> 6581 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6581 Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Ser Glu Asp Thr Ala Val His Tyr Cys Thr Thr Val Glu Gln Trp 20 25 30 Leu Leu Arg Gly Val Glu Tyr Trp Gly Gln Gly 35 40 <210> 6582 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6582 Cys Ala His Ser Pro Asn Glu Tyr Ser Ser Ser Ser Gly Tyr Phe Asp 1 5 10 15 Tyr Trp <210> 6583 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6583 acctccaaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacagccc caatgagtat agcagctcgt ccggctactt tgactactgg 120 ggccaggga 129 <210> 6584 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6584 Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Pro Asn Glu Tyr Ser Ser 20 25 30 Ser Ser Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6585 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6585 cacctccaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacagccc caatgagtat agcagctcgt ccggctactt tgactactgg 120 ggccaggga 129 <210> 6586 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6586 His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Pro Asn Glu Tyr Ser Ser 20 25 30 Ser Ser Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6587 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6587 Cys Ala Arg Gln Phe Leu Thr Lys Asp Ile Val Ile Leu Pro Ala Ala 1 5 10 15 Asp Asp Ala Phe Asp Ile Trp 20 <210> 6588 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6588 ttctccctga ggctgagctc tgtgaccgcc gcagacacgg ctgtgtattt ctgtgcgaga 60 cagttcttga cgaaggatat tgttatacta ccagctgccg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6589 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6589 Phe Ser Leu Arg Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr 1 5 10 15 Phe Cys Ala Arg Gln Phe Leu Thr Lys Asp Ile Val Ile Leu Pro Ala 20 25 30 Ala Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6590 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6590 ttctccctga ggccgagctc tgtgaccgcc gcagacacgg ctgtgtattt ctgtgcgaga 60 cagttcttga cgaaggatat tgttatacta ccagctgccg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6591 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6591 Phe Ser Leu Arg Pro Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr 1 5 10 15 Phe Cys Ala Arg Gln Phe Leu Thr Lys Asp Ile Val Ile Leu Pro Ala 20 25 30 Ala Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6592 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6592 Cys Ala Lys Asp Phe Tyr Gly Asp Pro Leu Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 6593 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6593 agagacaacg ccaagaactc cctgtatctg caaatgaaca gtctgagagc tgaggacacg 60 gccttgtatt actgtgcaaa agatttctac ggcgacccct tgtactactt tgactactgg 120 ggccaggga 129 <210> 6594 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6594 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Phe Tyr Gly Asp 20 25 30 Pro Leu Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6595 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6595 agagacaacg ccaagaactc cctgtatctg caaatgaaca gcctgagagc tgaggacacg 60 gccttgtatt actgtgcaaa agatttctac ggcgacccct tgtactactt tgactactgg 120 ggccaggga 129 <210> 6596 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6596 Cys Ala Lys Gly Gly Tyr Gly Ser Gly Glu Phe Asp Tyr Trp 1 5 10 <210> 6597 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6597 atctccatag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaggg ggctatggtt cgggagagtt tgactactgg 120 ggccaggga 129 <210> 6598 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6598 Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Tyr 20 25 30 Gly Ser Gly Glu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6599 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6599 atctccagag ataattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaggg ggctatggtt cgggagagtt tgactactgg 120 ggccaggga 129 <210> 6600 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6600 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Tyr 20 25 30 Gly Ser Gly Glu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6601 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6601 Cys Ala Ser His Pro Asn Trp Asp Ser Phe Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 6602 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6602 tccagagatg aatcaaagaa cacggcgtat ctgcaaatga acagcctgaa aaccgaggac 60 acggccgtgt attactgtgc tagccaccct aactgggatt cgttctactt tgactactgg 120 ggccaggga 129 <210> 6603 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6603 Ser Arg Asp Glu Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser His Pro Asn Trp 20 25 30 Asp Ser Phe Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6604 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6604 tccagagatc aatcaaacaa cacggcgtat ctgcaaatga acagcctgaa aaccgaggac 60 acggccgtgt attactgtgc tagccaccct aactgggatt cgttctactt tgactactgg 120 ggccaggga 129 <210> 6605 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6605 Ser Arg Asp Gln Ser Asn Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser His Pro Asn Trp 20 25 30 Asp Ser Phe Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6606 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6606 Cys Ala Lys Gly Leu Pro Arg Asp Leu Phe Asp Tyr Trp 1 5 10 <210> 6607 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6607 accatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaag gggcttcccc gggacctttt tgactactgg 120 ggccaggga 129 <210> 6608 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6608 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu 20 25 30 Pro Arg Asp Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6609 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6609 accatctcca gacacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaag gggcttcccc gggacctttt tgactactgg 120 ggccaggga 129 <210> 6610 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6610 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu 20 25 30 Pro Arg Asp Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6611 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6611 Cys Ala Arg Gly Pro Arg Val Val Thr Val Gly Thr Asp Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 6612 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6612 acgctgtatc ttcaaatgaa cagcctgaga gccgaggaca cggccgtgta ttactgtgcg 60 agagggccta gggtggtgac tgtaggaacc gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6613 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6613 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Pro Arg Val Val Thr Val Gly Thr Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6614 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6614 aagatgtatc ttcaaatgaa cagcctgaga gccgaggaca cggccgtgta ttactgtgcg 60 agagggccta gggtggtgac tgtaggaacc gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6615 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6615 Lys Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Pro Arg Val Val Thr Val Gly Thr Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6616 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6616 Cys Ala His Gly Val Gly Gly Trp Asp Gly Gln Tyr Phe Asp His Trp 1 5 10 15 <210> 6617 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6617 aaggacacct ccgaaaacca ggtggtccta acaatgacca acatggaacc tgcagacaca 60 gccacatact actgtgcaca cggtgttgga ggctgggatg ggcagtactt tgaccactgg 120 ggcccggga 129 <210> 6618 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6618 Lys Asp Thr Ser Glu Asn Gln Val Val Leu Thr Met Thr Asn Met Glu 1 5 10 15 Pro Ala Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Val Gly Gly Trp 20 25 30 Asp Gly Gln Tyr Phe Asp His Trp Gly Pro Gly 35 40 <210> 6619 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6619 aaggacacct ccaaaaacca ggtggtcctt acaatgaccg acatggaccc actggacaca 60 gccacatatt actgtgcaca cggtgttgga ggctgggatg gtcagtactt tgaccactgg 120 ggccaggga 129 <210> 6620 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6620 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asp Met Asp 1 5 10 15 Pro Leu Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Val Gly Gly Trp 20 25 30 Asp Gly Gln Tyr Phe Asp His Trp Gly Gln Gly 35 40 <210> 6621 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6621 Cys Thr Arg Val Tyr Asp Tyr Gly Asp Tyr Ser Val Gly Leu Asp Tyr 1 5 10 15 Trp <210> 6622 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6622 gttgattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagagt gtatgactac ggtgactact cggttggttt ggactactgg 120 ggccaggga 129 <210> 6623 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6623 Val Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Val Tyr Asp Tyr Gly Asp 20 25 30 Tyr Ser Val Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6624 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6624 gatgattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagagt gtatgactac ggtgactact cggttggttt ggactactgg 120 ggccaggga 129 <210> 6625 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6625 Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Val Tyr Asp Tyr Gly Asp 20 25 30 Tyr Ser Val Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6626 <211> 29 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6626 Cys Ala Arg Ala Glu Gly Ser Ser Ile Thr Ile Phe Gly Val Val Thr 1 5 10 15 Arg Ala Leu Ala Gly Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 6627 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6627 tgcctgagat ctgacgacac ggccgtgtat tactgtgcga gagctgaagg ttctagtatt 60 acgatttttg gagtggttac tagggccctc gcgggctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6628 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6628 Cys Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Glu 1 5 10 15 Gly Ser Ser Ile Thr Ile Phe Gly Val Val Thr Arg Ala Leu Ala Gly 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6629 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6629 agcctgagat ctgacgacac ggccgtgtat tactgtgcga gagctgaagg ttctagtatt 60 acgatttttg gagtggttac tagggccctc gcgggctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6630 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6630 Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Glu 1 5 10 15 Gly Ser Ser Ile Thr Ile Phe Gly Val Val Thr Arg Ala Leu Ala Gly 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6631 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6631 Cys Ala Arg Gly Asn Ile Ala Ala Ala Gly Thr Asn Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 6632 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6632 tgcacagcct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagaggca acatagcagc agctggtaca aactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6633 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6633 Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Asn Ile Ala Ala Ala Gly Thr Asn Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6634 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6634 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagaggca acatagcagc agctggtaca aactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6635 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6635 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Asn Ile Ala Ala Ala Gly Thr Asn Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6636 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6636 Cys Gly Arg Arg Gly Asn Phe Lys Tyr Ser Thr Pro Val Gly Asp Tyr 1 5 10 15 Trp <210> 6637 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6637 gacaacgcca tcaactcact gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgggaggag agggaatttt aagtatagca ccccggtggg ggactactgg 120 ggccaggga 129 <210> 6638 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6638 Asp Asn Ala Ile Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Gly Arg Arg Gly Asn Phe Lys Tyr 20 25 30 Ser Thr Pro Val Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 6639 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6639 gacaacgcca agaactcact gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgggaggag agggaatttt aagtatagca ccccggtggg ggactactgg 120 ggccaggga 129 <210> 6640 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6640 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Gly Arg Arg Gly Asn Phe Lys Tyr 20 25 30 Ser Thr Pro Val Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 6641 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6641 Cys Ala Arg Gly Leu Tyr Gly Gly Asn Arg Glu Gly Ala Tyr Trp 1 5 10 15 <210> 6642 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6642 tccagggaca acgccaacaa ttccctgtat ctgcaaatga acagtctcag agccgaggac 60 acggccttct attactgtgc gagaggtctc tacggtggta accgggaggg tgcctactgg 120 ggccaggga 129 <210> 6643 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6643 Ser Arg Asp Asn Ala Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Phe Tyr Tyr Cys Ala Arg Gly Leu Tyr Gly 20 25 30 Gly Asn Arg Glu Gly Ala Tyr Trp Gly Gln Gly 35 40 <210> 6644 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6644 tccagagaca acgccaacaa ttccctgtat ctgcaaatga acagtctcag agccgaggac 60 acggccttct attactgtgc gagaggtctc tacggtggta accgggaggg tgcctactgg 120 ggccaggga 129 <210> 6645 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6645 Cys Ala Arg Asp Ala Pro Ile Ala Ala Ser Trp Phe Asp Pro Trp 1 5 10 15 <210> 6646 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6646 accaggaact cctccataag aacagcctac atggagctga gcagcctgag atctgaggac 60 acggccgtgt attactgtgc gagggatgcc cccatagctg cgagctggtt cgacccctgg 120 ggccaggga 129 <210> 6647 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6647 Thr Arg Asn Ser Ser Ile Arg Thr Ala Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ala Pro Ile 20 25 30 Ala Ala Ser Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6648 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6648 accaggaact cctccataac aacagcctac atggagctga gcagcctgat atctgaggac 60 acggccgtgt attactgtgc gagggatgcc cccatagctg cgagctggtt cgacccctgg 120 ggccaggga 129 <210> 6649 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6649 Thr Arg Asn Ser Ser Ile Thr Thr Ala Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Ile Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ala Pro Ile 20 25 30 Ala Ala Ser Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6650 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6650 Cys Ala Thr Arg Lys Pro Glu Gly His Tyr Tyr Gly Met Asp Val Trp 1 5 10 15 <210> 6651 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6651 ttatataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgac tcgtaaacca gaaggccact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6652 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6652 Leu Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Arg Lys Pro Glu Gly 20 25 30 His Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6653 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6653 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgac tcgtaaacca gaaggccact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6654 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6654 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Arg Lys Pro Glu Gly 20 25 30 His Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6655 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6655 Cys Ala Arg Gly Arg Gly Val Arg Gly Ala Tyr Asp Tyr Trp 1 5 10 <210> 6656 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6656 ttatctgtag acacgtccaa gaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggctg tgtattactg tgcgagaggc cgtggggttc ggggagccta tgactactgg 120 ggccaggga 129 <210> 6657 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6657 Leu Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg Gly 20 25 30 Val Arg Gly Ala Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 6658 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6658 atatcagtag acacgtccaa gaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggctg tgtattactg tgcgagaggc cgtggggttc ggggagccta tgactactgg 120 ggccaggga 129 <210> 6659 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6659 Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg Gly 20 25 30 Val Arg Gly Ala Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 6660 <211> 26 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6660 Cys Ala Arg Gly Lys Gly Gly Gly Phe Thr Met Val Arg Gly Val Ile 1 5 10 15 Ile Gly Gly Tyr Asn Trp Phe Asp Pro Trp 20 25 <210> 6661 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6661 gtgctgagca gcctgagatc tgaggacacg gccgtgtatt actgtgcgag aggcaaaggc 60 gggggattta ctatggttcg gggagttatt ataggcgggt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 6662 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6662 Val Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala 1 5 10 15 Arg Gly Lys Gly Gly Gly Phe Thr Met Val Arg Gly Val Ile Ile Gly 20 25 30 Gly Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6663 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6663 gagctgagca gcctgagatc tgaggacacg gccgtgtatt actgtgcgag aggcaaaggc 60 gggggattta ctatggttcg gggagttatt ataggcgggt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 6664 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6664 Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala 1 5 10 15 Arg Gly Lys Gly Gly Gly Phe Thr Met Val Arg Gly Val Ile Ile Gly 20 25 30 Gly Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6665 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6665 Cys Ala Arg Asp Ile Val Gly Val Gly Asp Pro Pro Ile Pro Phe Asp 1 5 10 15 Tyr Trp <210> 6666 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6666 aaatccacga gcacagccta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagagatat cgtgggagtc ggtgacccac ccatcccgtt tgactactgg 120 ggccaggga 129 <210> 6667 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6667 Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ile Val Gly Val Gly Asp 20 25 30 Pro Pro Ile Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6668 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6668 aaatccacga gcacagccta catggagctg agcagcccga gatctgagga cacggccgtg 60 tattactgtg cgagagatat cgtgggagtc ggtgacccac ccatcccgtt tgactactgg 120 ggccaggga 129 <210> 6669 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6669 Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Pro Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ile Val Gly Val Gly Asp 20 25 30 Pro Pro Ile Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6670 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6670 Cys Ala Arg Arg Gly Tyr Phe Asp Val Trp 1 5 10 <210> 6671 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6671 tgtcgagtaa ccttattagt agacacgtcc aagagccagt tctccctgaa gctgacctct 60 gtgaccgccg cggacacggc tgtgtattac tgtgcgagaa ggggctactt cgatgtctgg 120 ggccgtggc 129 <210> 6672 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6672 Cys Arg Val Thr Leu Leu Val Asp Thr Ser Lys Ser Gln Phe Ser Leu 1 5 10 15 Lys Leu Thr Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Arg Arg Gly Tyr Phe Asp Val Trp Gly Arg Gly 35 40 <210> 6673 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6673 agtcgagtaa ccatattagt agacacgtcc aagagccagt tctccctgaa gctgacctct 60 gtgaccgccg cggacacggc tgtgtattac tgtgcgagaa ggggctactt cgatgtctgg 120 ggccgtggc 129 <210> 6674 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6674 Ser Arg Val Thr Ile Leu Val Asp Thr Ser Lys Ser Gln Phe Ser Leu 1 5 10 15 Lys Leu Thr Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Arg Arg Gly Tyr Phe Asp Val Trp Gly Arg Gly 35 40 <210> 6675 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6675 Cys Ala Arg Asp Arg Arg Pro Leu Ala Ala Ala Gly Tyr Leu Asp Tyr 1 5 10 15 Trp <210> 6676 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6676 gacacgtcca cgagcacagt ctacatggag ctgagcagcc tgagatctga ggacacggcc 60 gtgtattact gtgcgagaga caggcgcccc ctggcagcgg ctggttatct tgactactgg 120 ggccaggga 129 <210> 6677 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6677 Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Arg Pro Leu Ala 20 25 30 Ala Ala Gly Tyr Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6678 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6678 gacacgtcca cgagcacagt ctacatggag ctgagcagcc tgagatctga ggacacggcc 60 gtgtattact gtgcgagaga caggcgcccc ctggcagcag ctggttatct tgactactgg 120 ggccaggga 129 <210> 6679 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6679 Cys Ala Arg Asp Thr Asn Asp Phe Trp Ser Gly Tyr Ser Ile Asn Trp 1 5 10 15 Phe Asp Pro Trp 20 <210> 6680 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6680 gcgagcacag cctacatgga gctgagcagc ctgggatctg aagacacggc tgtgcattac 60 tgtgcgagag atacaaacga tttttggagt ggttattcta tcaactggtt cgacccctgg 120 ggccaggga 129 <210> 6681 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6681 Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Gly Ser Glu Asp Thr 1 5 10 15 Ala Val His Tyr Cys Ala Arg Asp Thr Asn Asp Phe Trp Ser Gly Tyr 20 25 30 Ser Ile Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6682 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6682 gcgagcacag cctacatgga gctgagcagc ctgagatctg aagacacggc tgtgtattac 60 tgtgcgagag atacaaacga tttttggagt ggttattcta tcaactggtt cgacccctgg 120 ggccaggga 129 <210> 6683 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6683 Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Asp Thr Asn Asp Phe Trp Ser Gly Tyr 20 25 30 Ser Ile Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6684 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6684 Cys Ala Arg Asp Gly Ser Leu Arg Gly Ile Ala Arg Gly Tyr Asp Tyr 1 5 10 15 Trp <210> 6685 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6685 gacaacgcca agaactcact gtatctgcaa atgaacagcc tgagagctga ggacacggcc 60 gtgtattact gtgcgagaga tggtagtctg cgcggtatag caagaggtta tgactactgg 120 ggccaggga 129 <210> 6686 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6686 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Gly Ser Leu Arg Gly 20 25 30 Ile Ala Arg Gly Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 6687 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6687 gacaacgcca agaactcact gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgcgagaga tggtagtctg cgcggtatag caagaggtta tgactactgg 120 ggccaggga 129 <210> 6688 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6688 Cys Ala Lys Asp Ile Gly Gln Leu Val Arg Glu Gly Gly Phe Asp Tyr 1 5 10 15 Trp <210> 6689 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6689 gacaacgcca agaactccct gtatctgcaa atgaacagtc tgagagctga ggacacggcc 60 ttgtattact gtgcaaaaga tatagggcag ctcgttcggg aaggcggctt tgactactgg 120 ggccaggga 129 <210> 6690 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6690 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Ile Gly Gln Leu Val 20 25 30 Arg Glu Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6691 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6691 gacaacgcca agaactccct gtatctgcaa atgaacactc tgagagctga ggacacggcc 60 ttctattact gtgcaaaaga tatagggcag ctcgttcggg aaggcggctt tgactactgg 120 ggccaggga 129 <210> 6692 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6692 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Thr Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Phe Tyr Tyr Cys Ala Lys Asp Ile Gly Gln Leu Val 20 25 30 Arg Glu Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6693 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6693 Cys Ala Lys Val Gly Ala Gly Trp Arg Val Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 6694 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6694 ttagataatc ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt attgtgcgaa agtgggggca gggtggcgcg tctactactt tgactactgg 120 ggccaggga 129 <210> 6695 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6695 Leu Asp Asn Pro Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Ala Gly Trp 20 25 30 Arg Val Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6696 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6696 agagataatc ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt attgtgcgaa agtgggggca gggtggcgcg tctactactt tgactactgg 120 ggccaggga 129 <210> 6697 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6697 Arg Asp Asn Pro Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly Ala Gly Trp 20 25 30 Arg Val Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6698 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6698 Cys Ala Lys Asp His Ser Ser Ser Trp Tyr Ser Ile Asp Tyr Trp 1 5 10 15 <210> 6699 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6699 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag aggcgaggac 60 acggccgtat attactgtgc gaaagaccat agcagcagct ggtattctat tgactactgg 120 ggccaggga 129 <210> 6700 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6700 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Gly Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp His Ser Ser 20 25 30 Ser Trp Tyr Ser Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 6701 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6701 tccagagata attccaagaa cacgctgtat ctcaaaatga accgcgtgag aggcgaggac 60 acggccgtat attactgtgc gaaagaccat agcagcagct ggtattctat tgactactgg 120 ggccaggga 129 <210> 6702 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6702 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Lys Met Asn Arg Val 1 5 10 15 Arg Gly Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp His Ser Ser 20 25 30 Ser Trp Tyr Ser Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 6703 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6703 Cys Thr Thr Asp Leu Gly Ala Gly Pro Arg Pro Phe Asp Asn Trp 1 5 10 15 <210> 6704 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6704 tcaagagatg attcaagaaa catgctgttt ctggacatga acaccgtgaa aacggacgac 60 acagccgtct atcactgcac cacagatctg ggagcgggac cacgcccctt tgacaactgg 120 ggccaggga 129 <210> 6705 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6705 Ser Arg Asp Asp Ser Arg Asn Met Leu Phe Leu Asp Met Asn Thr Val 1 5 10 15 Lys Thr Asp Asp Thr Ala Val Tyr His Cys Thr Thr Asp Leu Gly Ala 20 25 30 Gly Pro Arg Pro Phe Asp Asn Trp Gly Gln Gly 35 40 <210> 6706 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6706 tcaagagatg attcaagaaa cacgctgttt ctggaaatga acaccgtgaa aacggacgac 60 acagccgtct attactgcac cacagatctg ggagcgggac cacgcccctt tgacaactgg 120 ggccaggga 129 <210> 6707 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6707 Ser Arg Asp Asp Ser Arg Asn Thr Leu Phe Leu Glu Met Asn Thr Val 1 5 10 15 Lys Thr Asp Asp Thr Ala Val Tyr Tyr Cys Thr Thr Asp Leu Gly Ala 20 25 30 Gly Pro Arg Pro Phe Asp Asn Trp Gly Gln Gly 35 40 <210> 6708 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6708 Cys Ser Thr His Arg Gly Val Gly Gly Ser Gly Ser Tyr Leu Asp Asp 1 5 10 15 Trp <210> 6709 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6709 gacaattcca agaacacact ctatcttcaa atgaacagcc tgagagtcga cgacacggcc 60 gtgtattact gttcgactca tcggggggtg ggtggtagtg gctcctacct tgacgactgg 120 ggccaggga 129 <210> 6710 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6710 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Val 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ser Thr His Arg Gly Val Gly Gly 20 25 30 Ser Gly Ser Tyr Leu Asp Asp Trp Gly Gln Gly 35 40 <210> 6711 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6711 gacaattcca acaacacact ctatcttcaa atgaacagcc tgagagtcga cgacacggcc 60 gtgtattact gttcgactca tcggggggtg ggtggtagtg gctcctacct tgacgactgg 120 ggccaggga 129 <210> 6712 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6712 Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Val 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ser Thr His Arg Gly Val Gly Gly 20 25 30 Ser Gly Ser Tyr Leu Asp Asp Trp Gly Gln Gly 35 40 <210> 6713 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6713 Cys Ala Lys Asp Gln Trp Ala Ala Ala Gly Phe Asp Tyr Trp 1 5 10 <210> 6714 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6714 ttctccagag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat caatgggcag cagctggatt cgactactgg 120 ggccaggga 129 <210> 6715 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6715 Phe Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Gln Trp 20 25 30 Ala Ala Ala Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6716 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6716 atctccagag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaagat caatgggcag cagctggatt cgactactgg 120 ggccaggga 129 <210> 6717 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6717 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Gln Trp 20 25 30 Ala Ala Ala Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6718 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6718 Cys Ala Arg Asp Trp Gly Glu Glu Gln Trp Ser Tyr Trp 1 5 10 <210> 6719 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6719 accatgacca cagacacatc cacgagcaca gcctacatgg agctgaggag cctgagatct 60 gacgacacgg ccgtgtatta ctgtgcgaga gattgggggg aggagcagtg gtcctactgg 120 ggccaggga 129 <210> 6720 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6720 Thr Met Thr Thr Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg 1 5 10 15 Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Trp 20 25 30 Gly Glu Glu Gln Trp Ser Tyr Trp Gly Gln Gly 35 40 <210> 6721 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6721 accatgacca cacacacatc cacgagcaca gcctacatgg agctgaggag cctgagatct 60 gacgacacgg ccgtgtatta ctgtgcgaga gattgggggg aggagcagtg gtcctactgg 120 ggccaggga 129 <210> 6722 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6722 Thr Met Thr Thr His Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg 1 5 10 15 Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Trp 20 25 30 Gly Glu Glu Gln Trp Ser Tyr Trp Gly Gln Gly 35 40 <210> 6723 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6723 Cys Ala Arg Glu Asp His Phe Gly Met Asp Val Trp 1 5 10 <210> 6724 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6724 ttcaccatct cctgggacaa cgccaataac tcactgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtgta ttactgtgcg agagaggacc acttcggtat ggacgtctgg 120 ggccatggg 129 <210> 6725 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6725 Phe Thr Ile Ser Trp Asp Asn Ala Asn Asn Ser Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu 20 25 30 Asp His Phe Gly Met Asp Val Trp Gly His Gly 35 40 <210> 6726 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6726 ttcaccatct ccagggacaa cgccaagaac tcactgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtgta ttactgtgcg agagaggacc acttcggtat ggacgtctgg 120 ggccatggg 129 <210> 6727 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6727 Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu 20 25 30 Asp His Phe Gly Met Asp Val Trp Gly His Gly 35 40 <210> 6728 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6728 Cys Ala Arg Asp Met Pro Tyr Gly Ser Gly Ser Tyr Tyr Val Asp Tyr 1 5 10 15 Trp <210> 6729 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6729 gacacatcca tgagcacagc ctacacggag ctgaggagcc tgagatctga cgacacggcc 60 gtgtattact gtgcgagaga tatgccatat ggttcgggga gttattacgt tgactactgg 120 ggccaggga 129 <210> 6730 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6730 Asp Thr Ser Met Ser Thr Ala Tyr Thr Glu Leu Arg Ser Leu Arg Ser 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Met Pro Tyr Gly Ser 20 25 30 Gly Ser Tyr Tyr Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 6731 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6731 gacacatcca cgagcacagc ctacatggag ctgaggagcc tgagatctga cgacacggcc 60 gtgtattact gtgcgagaga tatgccatat ggttcgggga gttattacgt tgactactgg 120 ggccaggga 129 <210> 6732 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6732 Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Met Pro Tyr Gly Ser 20 25 30 Gly Ser Tyr Tyr Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 6733 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6733 Cys Ala Arg Gly Gly Tyr Cys Ser Gly Gly Ser Cys Tyr Ser Leu Tyr 1 5 10 15 Tyr Tyr Gly Met Asp Val Trp 20 <210> 6734 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6734 ctgtatctgc aaatgaacag tctgagagcc gaggacacgg ctgtgtatta ctgtgcaagg 60 ggtggatatt gtagtggtgg tagctgctac tccctctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6735 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6735 Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Gly Gly Tyr Cys Ser Gly Gly Ser Cys Tyr Ser Leu 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6736 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6736 ctgtatctgc aaatgaacag tctgagagcc gaggacacgg ctgtgtatta ctgtgcaaga 60 ggtggatatt gtagtggtgg tagctgctac tccctctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6737 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6737 Cys Ala Lys Glu Asp Tyr Gly Gly Asn Ser Pro Pro Phe Asp Tyr Trp 1 5 10 15 <210> 6738 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6738 agagataatt ccgagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agaggactac ggtggtaact cccctccctt tgactactgg 120 ggccaggga 129 <210> 6739 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6739 Arg Asp Asn Ser Glu Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Asp Tyr Gly Gly 20 25 30 Asn Ser Pro Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6740 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6740 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agaggactac ggtggtaact cccctccctt tgactactgg 120 ggccaggga 129 <210> 6741 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6741 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Asp Tyr Gly Gly 20 25 30 Asn Ser Pro Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6742 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6742 Cys Ala Arg Asp Tyr Gly Trp Gly Ile Ala Ala Ala Asp Gly Val Asp 1 5 10 15 Trp Phe Asp Pro Trp 20 <210> 6743 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6743 tgcacagcct acttggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagatt atggttgggg tatagcagca gctgatgggg tggactggtt cgacccctgg 120 ggccaggga 129 <210> 6744 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6744 Cys Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Tyr Gly Trp Gly Ile Ala Ala Ala Asp 20 25 30 Gly Val Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6745 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6745 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagatt atggttgggg tatagcagca gctgatgggg tggactggtt cgacccctgg 120 ggccaggga 129 <210> 6746 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6746 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Tyr Gly Trp Gly Ile Ala Ala Ala Asp 20 25 30 Gly Val Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6747 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6747 Cys Ala Lys Gly Phe Asp Tyr Gly Gly Asn Leu Asp Tyr Trp 1 5 10 <210> 6748 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6748 atctccatat ataattccaa gaacacagtc tctctacaaa tgaatagcct gagagccgag 60 gacacggccg catattactg tgcgaaaggg tttgactacg gtggtaacct tgattattgg 120 ggccaggga 129 <210> 6749 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6749 Ile Ser Ile Tyr Asn Ser Lys Asn Thr Val Ser Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Ala Tyr Tyr Cys Ala Lys Gly Phe Asp 20 25 30 Tyr Gly Gly Asn Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6750 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6750 atctccagag ataattccaa gaacacagtc tctctacaaa tgaatagcct gagagccgag 60 gacacggccg catattactg tgcgaaaggg tttgactacg gtggtaacct tgattattgg 120 ggccaggga 129 <210> 6751 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6751 Ile Ser Arg Asp Asn Ser Lys Asn Thr Val Ser Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Ala Tyr Tyr Cys Ala Lys Gly Phe Asp 20 25 30 Tyr Gly Gly Asn Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6752 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6752 Cys Ala Arg Asp Phe Ser Leu Ser Gln Trp Leu Val Arg Ser Arg Gly 1 5 10 15 Pro Asn Asp Ala Phe Asp Ile Trp 20 <210> 6753 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6753 tatctgcaaa tgaacagcct gagggacgag gacacggctg tgtattactg cgcgagagat 60 ttttcgttgt cgcagtggct ggtacgttct aggggaccaa atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6754 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6754 Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Asp Phe Ser Leu Ser Gln Trp Leu Val Arg Ser Arg Gly 20 25 30 Pro Asn Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6755 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6755 tatctgcaaa tgaacagcct gagagacgag gacacggctg tgtattactg tgcgagagat 60 ttttcgttgt cgcagtggct ggtacgttct aggggaccaa atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6756 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6756 Cys Ala Lys Phe Asp Gly Ser Glu Trp Tyr Phe Asp Leu Trp 1 5 10 <210> 6757 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6757 atctccatac acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaattt gatggcagcg agtggtactt cgatctctgg 120 ggccgtggc 129 <210> 6758 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6758 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Phe Asp Gly 20 25 30 Ser Glu Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 6759 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6759 atctccagag acaattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaattt gatggcagcg agtggtactt cgatctctgg 120 ggccgtggc 129 <210> 6760 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6760 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Phe Asp Gly 20 25 30 Ser Glu Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 6761 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6761 Cys Ala Arg Ile Ser Asp Gly Ser Gly Ser Gln Ile Asp Tyr Trp 1 5 10 15 <210> 6762 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6762 ctccaaggac acctccaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acggatatcg gatggttcgg ggagtcaaat tgactactgg 120 ggccaggga 129 <210> 6763 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6763 Leu Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Ser Asp Gly 20 25 30 Ser Gly Ser Gln Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 6764 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6764 tccaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acggatatcg gatggttcgg ggagtcaaat tgactactgg 120 ggccaggga 129 <210> 6765 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6765 Ser Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Ser Asp Gly 20 25 30 Ser Gly Ser Gln Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 6766 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6766 Cys Ala Arg Asp Cys Gly Asp Leu Arg Gly Ser Asn Cys Tyr Gly Asp 1 5 10 15 Ser Phe Asp Pro Trp 20 <210> 6767 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6767 aacactgtct acttggagct gaggagcctg agatctgacg acacggccgt atattactgt 60 gcaagagatt gcggggacct gcgtggttcc aactgctatg gggactcgtt cgacccctgg 120 ggccaggga 129 <210> 6768 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6768 Asn Thr Val Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Cys Gly Asp Leu Arg Gly Ser Asn Cys 20 25 30 Tyr Gly Asp Ser Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6769 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6769 aacacagtct acatggagct gaggagcctg agatctgacg acacggccgt atattactgt 60 gcaagagatt gcggggacct gcgtggttcc aactgctatg gggactcgtt cgacccctgg 120 ggccaggga 129 <210> 6770 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6770 Asn Thr Val Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Cys Gly Asp Leu Arg Gly Ser Asn Cys 20 25 30 Tyr Gly Asp Ser Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6771 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6771 Cys Ala Lys Gly Gln Asp Arg Tyr Ser Ser Gly Trp Tyr Tyr Tyr Trp 1 5 10 15 <210> 6772 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6772 agagacaatt ccaagaacgc gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gctgtgtatt actgtgcgaa aggccaagac cggtatagca gtggctggta ctactactgg 120 ggccaggga 129 <210> 6773 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6773 Arg Asp Asn Ser Lys Asn Ala Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gln Asp Arg Tyr 20 25 30 Ser Ser Gly Trp Tyr Tyr Tyr Trp Gly Gln Gly 35 40 <210> 6774 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6774 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gctgtgtatt actgtgcgaa aggccaagac cggtatagca gtggctggta ctactactgg 120 ggccaggga 129 <210> 6775 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6775 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gln Asp Arg Tyr 20 25 30 Ser Ser Gly Trp Tyr Tyr Tyr Trp Gly Gln Gly 35 40 <210> 6776 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6776 Cys Ala His Ser Gly Ile Thr Met Val Arg Gly Val Leu Asp Tyr Trp 1 5 10 15 <210> 6777 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6777 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagcggtatt actatggttc ggggagtttt agactactgg 120 ggccaggga 129 <210> 6778 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6778 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Gly Ile Thr Met 20 25 30 Val Arg Gly Val Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6779 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6779 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagcggtatt actatggttc ggggagtttt agactactgg 120 ggccaggga 129 <210> 6780 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6780 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Gly Ile Thr Met 20 25 30 Val Arg Gly Val Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6781 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6781 Cys Ala Lys Asp Phe His Gly Ile Ala Ala Ala Gly Ile Asp Tyr Trp 1 5 10 15 <210> 6782 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6782 ttagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agattttcac ggtatagcag cagctggaat tgactactgg 120 ggccaggga 129 <210> 6783 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6783 Leu Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Phe His Gly Ile 20 25 30 Ala Ala Ala Gly Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 6784 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6784 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agattttcac ggtatagcag cagctggaat tgactactgg 120 ggccaggga 129 <210> 6785 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6785 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Phe His Gly Ile 20 25 30 Ala Ala Ala Gly Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 6786 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6786 Cys Gly Arg Asp Ala Arg Ser Ser Gly Tyr Ser Gly Tyr Asp Met Phe 1 5 10 15 Asp Ile Trp <210> 6787 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6787 tccatcagca cagccttcat ggaacttagc agtctgagat atgacgacac ggccgtatat 60 tactgtggga gagatgcacg gtctagtggc tacagtggat atgatatgtt tgatatctgg 120 ggccaaggg 129 <210> 6788 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6788 Ser Ile Ser Thr Ala Phe Met Glu Leu Ser Ser Leu Arg Tyr Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Gly Arg Asp Ala Arg Ser Ser Gly Tyr Ser 20 25 30 Gly Tyr Asp Met Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6789 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6789 tccatcagca aagccttcat ggaacttagc agtctgagat atgacgacac ggccgtatat 60 tactgtggga gagatgcacg gtctagtggc tacagtggat atgatatgtt tgatatctgg 120 ggccaaggg 129 <210> 6790 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6790 Ser Ile Ser Lys Ala Phe Met Glu Leu Ser Ser Leu Arg Tyr Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Gly Arg Asp Ala Arg Ser Ser Gly Tyr Ser 20 25 30 Gly Tyr Asp Met Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6791 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6791 Cys Ala Arg Val Arg Ala Gly Gly Val Phe Asp Leu Trp 1 5 10 <210> 6792 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6792 accatctcct gggacaacgc caagaactca ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gtgagagccg ggggtgtttt tgatctctgg 120 ggccaaggg 129 <210> 6793 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6793 Thr Ile Ser Trp Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Arg 20 25 30 Ala Gly Gly Val Phe Asp Leu Trp Gly Gln Gly 35 40 <210> 6794 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6794 accatctcca gggacaacgc caagaactca ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gtgagagccg ggggtgtttt tgatctctgg 120 ggccaaggg 129 <210> 6795 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6795 Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Arg 20 25 30 Ala Gly Gly Val Phe Asp Leu Trp Gly Gln Gly 35 40 <210> 6796 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6796 Cys Ala Lys Asp Pro Lys Thr Thr Val Ser Arg Leu Met Ser Tyr Trp 1 5 10 15 <210> 6797 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6797 ttagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatcctaaa actacggtgt cccgcctaat gagctactgg 120 ggccaggga 129 <210> 6798 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6798 Leu Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Lys Thr Thr 20 25 30 Val Ser Arg Leu Met Ser Tyr Trp Gly Gln Gly 35 40 <210> 6799 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6799 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatcctaaa actacggtgt cccgcctaat gagctactgg 120 ggccaggga 129 <210> 6800 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6800 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Lys Thr Thr 20 25 30 Val Ser Arg Leu Met Ser Tyr Trp Gly Gln Gly 35 40 <210> 6801 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6801 Cys Ala Lys Asp Leu Asp Ile Ala Val Ala Gly Ser Val Gly Phe Asp 1 5 10 15 Tyr Trp <210> 6802 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6802 aacgccaaga actccgtgta tctgcaaatg gacagtctga gagctgagga cacggcctta 60 tattactgtg caaaagactt ggatatagca gtggctggta gtgtgggctt tgactactgg 120 ggccaggga 129 <210> 6803 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6803 Asn Ala Lys Asn Ser Val Tyr Leu Gln Met Asp Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Leu Asp Ile Ala Val Ala 20 25 30 Gly Ser Val Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6804 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6804 aacgccaaga actccgtgta tctgcaaatg aacagtctga gagctgagga cacggcctta 60 tattactgtg caaaagactt ggatatagca gtggctggta gtgtgggctt tgactactgg 120 ggccaggga 129 <210> 6805 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6805 Asn Ala Lys Asn Ser Val Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Leu Asp Ile Ala Val Ala 20 25 30 Gly Ser Val Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6806 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6806 Cys Ala Arg Asp Glu Arg Thr Met Val Arg Gly Glu Tyr Asp Tyr Trp 1 5 10 15 <210> 6807 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6807 tgggacacgt ccatcagcac agcctacatg gagctgagca ggctgagatc tgacgacacg 60 gccgtgtatt actgtgcgag agatgaacgt actatggttc ggggagaata tgactactgg 120 ggccaggga 129 <210> 6808 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6808 Trp Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Glu Arg Thr Met 20 25 30 Val Arg Gly Glu Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 6809 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6809 agggacacgt ccatcagcac agcctacatg gagctgagca ggctgagatc tgacgacacg 60 gccgtgtatt actgtgcgag agatgaacgt actatggttc ggggagaata tgactactgg 120 ggccaggga 129 <210> 6810 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6810 Arg Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Glu Arg Thr Met 20 25 30 Val Arg Gly Glu Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 6811 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6811 Cys Ala His Arg Lys Arg Asp Tyr Gly Asn His Leu Val Phe Asp Pro 1 5 10 15 Trp <210> 6812 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6812 gacacctcca cagaccaggt ggtcctttcc atgaccgaca tggaccctgt ggacacaggc 60 acatattatt gtgcacacag aaaaagagat tatggaaatc acttggtgtt cgacccctgg 120 ggccaggga 129 <210> 6813 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6813 Asp Thr Ser Thr Asp Gln Val Val Leu Ser Met Thr Asp Met Asp Pro 1 5 10 15 Val Asp Thr Gly Thr Tyr Tyr Cys Ala His Arg Lys Arg Asp Tyr Gly 20 25 30 Asn His Leu Val Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6814 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6814 ggacacctcc acagaccagg tggtctttcc gtgaccgaca tggaccctgt ggacacaggc 60 tcatattatt gtgcacacag aaaaagagat tatggaaatc acttggtgtt cgacccctgg 120 ggccaggga 129 <210> 6815 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6815 Gly His Leu His Arg Pro Gly Gly Leu Ser Val Thr Asp Met Asp Pro 1 5 10 15 Val Asp Thr Gly Ser Tyr Tyr Cys Ala His Arg Lys Arg Asp Tyr Gly 20 25 30 Asn His Leu Val Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6816 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6816 Cys Ala Arg Asp Arg Pro Gly Ala Ala Ala Gly Asp Tyr Trp 1 5 10 <210> 6817 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6817 attaccgcgg acaaatccac gagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagagat cgacccgggg cagcagctgg tgactactgg 120 ggccaggga 129 <210> 6818 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6818 Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Pro 20 25 30 Gly Ala Ala Ala Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 6819 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6819 attaccgcgc acaaatccac gaccacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagagat cgacccgggg cagcagctgg tgactactgg 120 ggccaggga 129 <210> 6820 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6820 Ile Thr Ala His Lys Ser Thr Thr Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Pro 20 25 30 Gly Ala Ala Ala Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 6821 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6821 Cys Ala Arg Asp Glu Tyr Asp Tyr Val Trp Gly Ser Tyr Arg Pro His 1 5 10 15 Tyr Phe Asp Tyr Trp 20 <210> 6822 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6822 tgcacagcct acttggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagacg agtatgatta cgtttggggg agttatcgtc ctcactactt tgactactgg 120 ggccaggga 129 <210> 6823 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6823 Cys Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Glu Tyr Asp Tyr Val Trp Gly Ser Tyr 20 25 30 Arg Pro His Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6824 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6824 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagacg agtatgatta cgtttggggg agttatcgtc ctcactactt tgactactgg 120 ggccaggga 129 <210> 6825 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6825 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Glu Tyr Asp Tyr Val Trp Gly Ser Tyr 20 25 30 Arg Pro His Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6826 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6826 Cys Ala Arg Ala Gly Gly Ala Trp Gly Ile Val Gly Leu Asp Tyr Trp 1 5 10 15 <210> 6827 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6827 tgggacacat ccgcgagcac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 gctgtgtatt actgtgcgag agcgggcggg gcctggggta ttgtagggct ggactactgg 120 ggccaggga 129 <210> 6828 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6828 Trp Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Gly Gly Ala Trp 20 25 30 Gly Ile Val Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6829 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6829 agggacacat ccgcgagcac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 gctgtgtatt actgtgcgag agcgggcggg gcctggggta ttgtagggct ggactactgg 120 ggccaggga 129 <210> 6830 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6830 Arg Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Gly Gly Ala Trp 20 25 30 Gly Ile Val Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6831 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6831 Cys Ala Lys Val His Asp Ser Ser Gly Tyr Tyr Trp Val Tyr Phe Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 6832 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6832 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaggtccacg atagtagtgg ttattattgg gtctacttct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6833 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6833 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Val His Asp Ser Ser Gly Tyr Tyr Trp Val Tyr 20 25 30 Phe Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6834 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6834 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaggtccacg atagtagtgg ttattattgg gtctacttct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6835 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6835 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Val His Asp Ser Ser Gly Tyr Tyr Trp Val Tyr 20 25 30 Phe Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6836 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6836 Cys Ala Arg Gly Pro Val Asp Ser Gly Tyr Asp Trp Arg Gly Pro Gly 1 5 10 15 Ala Phe Asp Ile Trp 20 <210> 6837 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6837 agcactgcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagggc cggttgatag tggctacgat tggaggggcc cgggcgcttt tgatatctgg 120 ggccaaggg 129 <210> 6838 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6838 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Pro Val Asp Ser Gly Tyr Asp Trp Arg 20 25 30 Gly Pro Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6839 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6839 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagggc cggttgatag tggctacgat tggaggggcc cgggcgcttt tgatatctgg 120 ggccaaggg 129 <210> 6840 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6840 Cys Ala Lys Gly Gly Gly Tyr Tyr Tyr Asp Asn Ser Gly Tyr Val Gly 1 5 10 15 Tyr Trp <210> 6841 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6841 acttccaaga acacgctgtt tctgcaaatg agcagcctga gagtcgagga cacggccgta 60 tattactgtg cgaagggggg cgggtattac tatgataata gtggttatgt tggctactgg 120 ggccaggga 129 <210> 6842 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6842 Thr Ser Lys Asn Thr Leu Phe Leu Gln Met Ser Ser Leu Arg Val Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Gly Tyr Tyr Tyr Asp 20 25 30 Asn Ser Gly Tyr Val Gly Tyr Trp Gly Gln Gly 35 40 <210> 6843 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6843 aattccaaga acacgctgtt tctgcaaatg agcagcctga gagtcgagga cacggccgta 60 tattactgtg cgaagggggg cgggtattac tatgataata gtggttatgt tggctactgg 120 ggccaggga 129 <210> 6844 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6844 Asn Ser Lys Asn Thr Leu Phe Leu Gln Met Ser Ser Leu Arg Val Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Gly Tyr Tyr Tyr Asp 20 25 30 Asn Ser Gly Tyr Val Gly Tyr Trp Gly Gln Gly 35 40 <210> 6845 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6845 Cys Thr His Asn Leu Gly Gly Trp Asp Gly Gln Tyr Ser Asp Tyr Trp 1 5 10 15 <210> 6846 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6846 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt tctgtacaca caatcttgga ggctgggatg ggcagtactc tgactactgg 120 ggccaggga 129 <210> 6847 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6847 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Phe Cys Thr His Asn Leu Gly Gly Trp 20 25 30 Asp Gly Gln Tyr Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 6848 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6848 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtagacaca 60 gccacatatt tctgtacaca caatcttgga ggctgggatg ggcagtactc tgactactgg 120 ggccaggga 129 <210> 6849 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6849 Cys Ala Arg Asp Arg Tyr Gly Ser Gly Leu Asp Tyr Trp 1 5 10 <210> 6850 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6850 accatctcca gagacaacgc caagaacacg ctgtatctgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtgtatta ctgtgcaaga gatcgttatg gttcgggcct cgactactgg 120 ggccagggg 129 <210> 6851 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6851 Thr Ile Ser Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg 20 25 30 Tyr Gly Ser Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6852 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6852 accatctcca gagacaacgc caagaacacg ctgtatctgc aaatgaacag tctgagagcc 60 gaggacacgg ctgtgtatta ctgtgcaaga gatcgttatg gttcgggcct cgactactgg 120 ggccaggga 129 <210> 6853 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6853 Cys Ala Lys Asp Arg Arg Glu Gln Gln Leu Asp Leu Arg Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 6854 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6854 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggctgtgta ttactgtgcg 60 aaagatcgaa gggagcagca gctggacctt cggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6855 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6855 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Arg Arg Glu Gln Gln Leu Asp Leu Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6856 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6856 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggctgtgta ttactgtgcg 60 aaagatcgaa gggagcagca gctggacctt cggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6857 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6857 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Arg Arg Glu Gln Gln Leu Asp Leu Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6858 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6858 Cys Ala His Ser Ser Thr Ile Leu Tyr Tyr Phe Asp Tyr Trp 1 5 10 <210> 6859 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6859 catcaccaag gacacctcca aaaccaggtg gtccttacaa tgaccaacat ggaccctgtg 60 gacacagcca catattactg tgcacacagt tctacgatat tatattactt tgactactgg 120 ggccaggga 129 <210> 6860 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6860 His His Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Ser Thr 20 25 30 Ile Leu Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6861 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6861 atcaccaagg acacctccaa aaaccaggtg gtccttacaa tgaccaacat ggaccctgtg 60 gacacagcca catattactg tgcacacagt tctacgatat tatattactt tgactactgg 120 ggccaggga 129 <210> 6862 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6862 Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Ser Thr 20 25 30 Ile Leu Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6863 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6863 Cys Ala Arg Asp Phe Arg His Tyr Gly Asp Tyr Gly Lys Gly Val Gly 1 5 10 15 Arg Tyr Trp Phe Asp Pro Trp 20 <210> 6864 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6864 gcctacatgg agctgagcag cctgagatct gaggacacgg ccgtgtatta ctgtgcgaga 60 gacttccgac actacggtga ctatgggaag ggggtcgggc ggtactggtt cgacccctgg 120 ggccaggga 129 <210> 6865 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6865 Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Asp Phe Arg His Tyr Gly Asp Tyr Gly Lys Gly Val 20 25 30 Gly Arg Tyr Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6866 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6866 Cys Val Arg Thr Lys Thr Met Met Pro Ser Gly Thr Tyr Phe Tyr Tyr 1 5 10 15 Trp <210> 6867 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6867 gacatttcac tcagtaccgc ctacctgcac tggaacagcc tgcggtcctc cgacaccggc 60 atttatttct gtgtgcgaac gaagactatg atgccttcgg ggacttattt ctactactgg 120 ggccaggga 129 <210> 6868 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6868 Asp Ile Ser Leu Ser Thr Ala Tyr Leu His Trp Asn Ser Leu Arg Ser 1 5 10 15 Ser Asp Thr Gly Ile Tyr Phe Cys Val Arg Thr Lys Thr Met Met Pro 20 25 30 Ser Gly Thr Tyr Phe Tyr Tyr Trp Gly Gln Gly 35 40 <210> 6869 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6869 gacatttcac tcagtaccgc ctacctgcac tggaacaccc tgcggtcctc cgacaccggc 60 atttatttct gtgtgcgaac gaagactatg atgccttcgg ggacttattt ctactactgg 120 ggccaggga 129 <210> 6870 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6870 Asp Ile Ser Leu Ser Thr Ala Tyr Leu His Trp Asn Thr Leu Arg Ser 1 5 10 15 Ser Asp Thr Gly Ile Tyr Phe Cys Val Arg Thr Lys Thr Met Met Pro 20 25 30 Ser Gly Thr Tyr Phe Tyr Tyr Trp Gly Gln Gly 35 40 <210> 6871 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6871 Cys Ala Gly Val Asp Gly Asp Glu His Pro Tyr Tyr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 6872 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6872 aagaacacgc tgtatcttca aatgaacagc ctgagagccg aggacacggc cgtgtattac 60 tgcgccgggg tggacggtga cgaacacccc tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6873 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6873 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Gly Val Asp Gly Asp Glu His Pro Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6874 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6874 aacaacacgc tgtatctaca aatgaacagc ctgagagccg aggacacggc cgtgtattac 60 tgcgccgggg tggacggtga cgaacacccc tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6875 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6875 Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Gly Val Asp Gly Asp Glu His Pro Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6876 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6876 Cys Ala Arg Gly Arg Leu Arg Val Gly Tyr Tyr Tyr Gly Ser Gly Ser 1 5 10 15 Tyr Tyr Leu Ala Ser Phe Ala Tyr Trp 20 25 <210> 6877 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6877 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagaggtcgt 60 ttaagagtgg ggtattacta tggttcgggg agttattatc tggcctcctt tgcctactgg 120 ggccaggga 129 <210> 6878 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6878 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Arg Leu Arg Val Gly Tyr Tyr Tyr Gly Ser Gly Ser Tyr 20 25 30 Tyr Leu Ala Ser Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 6879 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6879 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagaggtcgt 60 ttaagagtgg ggtattacta tggttcgggg agttattatc tggcctcctt tgcctactgg 120 ggccaggga 129 <210> 6880 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6880 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Arg Leu Arg Val Gly Tyr Tyr Tyr Gly Ser Gly Ser Tyr 20 25 30 Tyr Leu Ala Ser Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 6881 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6881 Cys Ala Arg Gly Pro Arg Leu Arg Gly Tyr Ser Ser Ser Ser Tyr Pro 1 5 10 15 Asn Trp Phe Asp Pro Trp 20 <210> 6882 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6882 acggcatatc tgcagatcag cagcctaaag gctgaggaca ctgccgtgta ttactgtgcg 60 agaggcccga ggcttagggg gtatagcagc tcgtcctacc ctaactggtt cgacccctgg 120 ggccgggga 129 <210> 6883 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6883 Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Pro Arg Leu Arg Gly Tyr Ser Ser Ser Ser 20 25 30 Tyr Pro Asn Trp Phe Asp Pro Trp Gly Arg Gly 35 40 <210> 6884 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6884 acggcatatc tgcagatcag cagcctaaag gctgaggaca ctgccgtgta ttactgtgcg 60 agaggcccga ggcttagggg gtatagcagc tcgtcctacc ctaactggtt cgacccctgg 120 ggccaggga 129 <210> 6885 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6885 Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Pro Arg Leu Arg Gly Tyr Ser Ser Ser Ser 20 25 30 Tyr Pro Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 6886 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6886 Cys Ala Lys Asp Tyr Tyr Tyr Asp Ser Ser Gly Tyr Val Asp Ala Phe 1 5 10 15 Asp Ile Trp <210> 6887 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6887 tccaagaact cgatgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aagattacta ctatgatagt agtggttacg ttgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6888 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6888 Ser Lys Asn Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Asp Tyr Tyr Tyr Asp Ser Ser Gly 20 25 30 Tyr Val Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6889 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6889 tccaagaaca cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aagattacta ctatgatagt agtggttacg ttgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6890 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6890 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Asp Tyr Tyr Tyr Asp Ser Ser Gly 20 25 30 Tyr Val Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6891 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6891 Cys Thr Arg Thr Phe Gly Thr Pro Ala Ser Tyr Tyr Tyr Tyr Gly Met 1 5 10 15 Asp Val Trp <210> 6892 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6892 tcaaagaaca cggcgtatct gcaaatgaac agcctgaaaa ccgaggacac ggccgtgtat 60 tactgtacta ggacgttcgg gacccctgcc tcctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6893 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6893 Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Arg Thr Phe Gly Thr Pro Ala Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6894 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6894 caaagaacca cggcgtatct gcaaatgaac agcctgaaaa ccgaggacac ggccgtgtat 60 tactgtacta ggacgttcgg gacccctgcc tcctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6895 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6895 Gln Arg Thr Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Arg Thr Phe Gly Thr Pro Ala Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6896 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6896 Cys Ala Arg Asp Leu Met Val Arg Gly Val Ser Leu Asp Ala Phe Asp 1 5 10 15 Ile Trp <210> 6897 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6897 aaatccacgt gcacagccta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagagatct aatggttcgg ggagtcagtt tagatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6898 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6898 Lys Ser Thr Cys Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu Met Val Arg Gly Val 20 25 30 Ser Leu Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6899 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6899 aaatccacga gcacagccta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagagatct aatggttcgg ggagtcagtt tagatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6900 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6900 Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu Met Val Arg Gly Val 20 25 30 Ser Leu Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6901 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6901 Cys Ala Lys Tyr Asn Tyr Ile Trp Gly Ser Tyr Arg Tyr Lys Tyr Phe 1 5 10 15 Asp Tyr Trp <210> 6902 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6902 tccaagaaca cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aatacaatta catttggggg agttatcgct ataagtactt tgactactgg 120 ggccaggga 129 <210> 6903 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6903 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Tyr Asn Tyr Ile Trp Gly Ser Tyr 20 25 30 Arg Tyr Lys Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6904 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6904 tccaagaaca cgctgtatct gcaaatgaac agcctgaaag ccgaggacac ggccgtatat 60 tactgtgcga aatacaatta catttggggg agttatcgct ataagtactt tgactactgg 120 ggccaggga 129 <210> 6905 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6905 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Tyr Asn Tyr Ile Trp Gly Ser Tyr 20 25 30 Arg Tyr Lys Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6906 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6906 Cys Ala Arg Arg Thr Val Tyr Tyr Asp Ile Leu Thr Gly Ser Lys Ala 1 5 10 15 Asp Leu Asp Tyr Trp 20 <210> 6907 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6907 tgcacagcct acttggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagaagga ctgtgtatta cgatattttg actggttcga aagccgacct tgactactgg 120 ggccaggga 129 <210> 6908 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6908 Cys Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Arg Thr Val Tyr Tyr Asp Ile Leu Thr Gly 20 25 30 Ser Lys Ala Asp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6909 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6909 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagaagga ctgtgtatta cgatattttg actggttcga aagccgacct tgactactgg 120 ggccaggga 129 <210> 6910 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6910 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Arg Thr Val Tyr Tyr Asp Ile Leu Thr Gly 20 25 30 Ser Lys Ala Asp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 6911 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6911 Cys Ala Lys Asp Gly Ile Ala Val Ala Gly Thr Tyr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 6912 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6912 aagaatacgc tgtatctgca aatgaacagc ctgagagccg aggacatggc cgtatattac 60 tgtgcgaaag atggcatagc agtggctggc acttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6913 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6913 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Met 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Asp Gly Ile Ala Val Ala Gly Thr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6914 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6914 aagaacacgc tgtatctgca aatgaacagc ctgagagccg aggacacggc cgtatattac 60 tgtgcgaaag atggcatagc agtggctggc acttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6915 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6915 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Asp Gly Ile Ala Val Ala Gly Thr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6916 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6916 Cys Ala Lys Asp Ser His Leu Ala Pro Arg Asp Pro Gly Ser Tyr Ala 1 5 10 15 Gly Ile Phe Asp Tyr Trp 20 <210> 6917 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6917 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagattctc atctcgcgcc ccgggatccg gggagctacg cagggatctt tgactactgg 120 ggccaggga 129 <210> 6918 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6918 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Ser His Leu Ala Pro Arg Asp Pro Gly Ser 20 25 30 Tyr Ala Gly Ile Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6919 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6919 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagattctc atctcgcgcc ccgggatccg gggagctacg cagggatctt tgactactgg 120 ggccaggga 129 <210> 6920 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6920 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Ser His Leu Ala Pro Arg Asp Pro Gly Ser 20 25 30 Tyr Ala Gly Ile Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6921 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6921 Cys Ala Arg Gly Asp Met Gly Leu Trp Phe Gly Glu Leu Arg Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 6922 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6922 aagaaccagt tctccctgaa gctgagctct gtgactgccg cggacacggc cgtgtattac 60 tgtgcgagag gcgacatggg cctatggttc ggggagttac gatacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6923 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6923 Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Asp Met Gly Leu Trp Phe Gly Glu 20 25 30 Leu Arg Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6924 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6924 aacaaccagt tctccctgac gctgagctct gtgactgccg cggacacggc cgtgtattac 60 tgtgcgagag gcgacatggg cctatggttc ggggagttac gatacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6925 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6925 Asn Asn Gln Phe Ser Leu Thr Leu Ser Ser Val Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Asp Met Gly Leu Trp Phe Gly Glu 20 25 30 Leu Arg Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6926 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6926 Cys Ala Thr Val Glu Ala Ser Gly Ser Pro Trp 1 5 10 <210> 6927 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6927 agagtcacca taaccgcgga cacgtctaca gacacagcct acatggagct gagcagcctg 60 agatctgagg acacggccgt atattactgt gcaacagtgg aggctagtgg gagcccttgg 120 ggccaggga 129 <210> 6928 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6928 Arg Val Thr Ile Thr Ala Asp Thr Ser Thr Asp Thr Ala Tyr Met Glu 1 5 10 15 Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr 20 25 30 Val Glu Ala Ser Gly Ser Pro Trp Gly Gln Gly 35 40 <210> 6929 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6929 agagacacca taaccgcgca cacgtcaaca gacacagcct acatggagct gagcagcctt 60 agatctgagg acacggccgt atattactgt gcaacagtgg aggctagtgg gagcccttgg 120 ggccaggga 129 <210> 6930 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6930 Arg Asp Thr Ile Thr Ala His Thr Ser Thr Asp Thr Ala Tyr Met Glu 1 5 10 15 Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr 20 25 30 Val Glu Ala Ser Gly Ser Pro Trp Gly Gln Gly 35 40 <210> 6931 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6931 Cys Ala Arg Glu Ser Leu Thr Thr Ile Ala Ala Ala Gly Glu Asn Tyr 1 5 10 15 Phe Asp Tyr Trp 20 <210> 6932 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6932 tcgagcacag cctacatgga gctgaggagc ctgagatctg acgacacggc cgtgtattac 60 tgtgcgagag agagcctcac gacaatagca gcagctgggg aaaactactt tgactactgg 120 ggccaggga 129 <210> 6933 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6933 Ser Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Glu Ser Leu Thr Thr Ile Ala Ala Ala 20 25 30 Gly Glu Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6934 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6934 acgagcacag cctacatgga gctgaggagc ctgagatctg acgacacggc cgtgtattac 60 tgtgcgagag agagcctcac gacaatagca gcagctgggg aaaactactt tgactactgg 120 ggccaggga 129 <210> 6935 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6935 Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Glu Ser Leu Thr Thr Ile Ala Ala Ala 20 25 30 Gly Glu Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6936 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6936 Cys Ala Arg Asp Gly Glu Tyr Ser Ser Gly Trp Thr Gly Thr Gly Ser 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 6937 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6937 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagacggg 60 gagtatagca gtggctggac aggaactgga tcctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6938 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6938 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Asp Gly Glu Tyr Ser Ser Gly Trp Thr Gly Thr Gly Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6939 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6939 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagacggg 60 gagtatagca gtggctggac aggaactgga tcctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6940 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6940 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Asp Gly Glu Tyr Ser Ser Gly Trp Thr Gly Thr Gly Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6941 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6941 Cys Ala Lys Asp Thr Ser Trp Ala Thr Ala Glu Thr Tyr Phe Asp Tyr 1 5 10 15 Trp <210> 6942 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6942 gacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattatt gtgcgaaaga tacgtcctgg gctacagccg agacctactt tgactactgg 120 ggccaggga 129 <210> 6943 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6943 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Thr Ser Trp Ala Thr 20 25 30 Ala Glu Thr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6944 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6944 cacaattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattatt gtgcgaaaga tacgtcctgg gctacagccg agacctactt tgactactgg 120 ggccaggga 129 <210> 6945 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6945 His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Thr Ser Trp Ala Thr 20 25 30 Ala Glu Thr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6946 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6946 Cys Ala Arg Asp Arg Gln Glu Thr Tyr Ser Ser Ser Trp Tyr Asp Tyr 1 5 10 15 Pro Val Phe Tyr Gly Met Asp Val Trp 20 25 <210> 6947 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6947 cttcaaatga acagcctgag agccgaggac acggccgtgt attactgtgc gagagatcgt 60 caagaaacgt atagcagcag ctggtacgat tacccggttt tctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6948 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6948 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Asp Arg Gln Glu Thr Tyr Ser Ser Ser Trp Tyr Asp Tyr Pro 20 25 30 Val Phe Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6949 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6949 cttaaaatga accgcctgag agccgaggac acggccgtgt attactgtgc gagagatcgt 60 caagaaacgt atagcagcag ctggtacgat tacccggttt tctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6950 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6950 Leu Lys Met Asn Arg Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Asp Arg Gln Glu Thr Tyr Ser Ser Ser Trp Tyr Asp Tyr Pro 20 25 30 Val Phe Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6951 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6951 Cys Ala Arg Glu Val Asn Asp Asp Phe Trp Ser Gly Tyr Phe Thr Tyr 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 6952 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6952 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagaagtc 60 aatgacgatt tttggagtgg ttactttact tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6953 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6953 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Glu Val Asn Asp Asp Phe Trp Ser Gly Tyr Phe Thr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6954 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6954 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagaagtc 60 aatgacgatt tttggagtgg ttactttact tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 6955 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6955 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Glu Val Asn Asp Asp Phe Trp Ser Gly Tyr Phe Thr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 6956 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6956 Cys Ala Arg Ala Lys Ala Ala Ala Asp Arg Thr Ser Ala Phe Asp Ile 1 5 10 15 Cys <210> 6957 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6957 gacacgtcca tcagcgcagc ctacatggag ctgagcaggc tgagatctga cgacacggcc 60 gtgtattact gtgcgagggc taaagcagca gctgaccgga ctagtgcttt tgatatctgt 120 ggccaaggg 129 <210> 6958 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6958 Asp Thr Ser Ile Ser Ala Ala Tyr Met Glu Leu Ser Arg Leu Arg Ser 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Lys Ala Ala Ala Asp 20 25 30 Arg Thr Ser Ala Phe Asp Ile Cys Gly Gln Gly 35 40 <210> 6959 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6959 gacacgtcca tcagcacagc ctacatggag ctgagcaggc tgagatctga cgacacggcc 60 gtgtattact gtgcgagggc taaagcagca gctgaccgga ctagtgcttt tgatatctgt 120 ggccaaggg 129 <210> 6960 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6960 Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg Ser 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Lys Ala Ala Ala Asp 20 25 30 Arg Thr Ser Ala Phe Asp Ile Cys Gly Gln Gly 35 40 <210> 6961 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6961 Cys Ala Lys Val Met Val Val Ala Phe His Arg Asp Ala Phe Asp Ile 1 5 10 15 Trp <210> 6962 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6962 gacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaagt gatggtggta gctttccata gggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6963 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6963 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Met Val Val Ala Phe 20 25 30 His Arg Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6964 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6964 cacaattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaagt gatggtggta gctttccata gggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6965 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6965 His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Met Val Val Ala Phe 20 25 30 His Arg Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6966 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6966 Cys Ala Lys Asp Phe Pro Val Tyr Arg Ala Pro Arg Pro Asn Ala Phe 1 5 10 15 Asp Ile Trp <210> 6967 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6967 tccaagaaca cgctgtatct gcagatgagc agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aagattttcc cgtttatcgc gcaccccgcc caaatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6968 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6968 Ser Lys Asn Thr Leu Tyr Leu Gln Met Ser Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Asp Phe Pro Val Tyr Arg Ala Pro 20 25 30 Arg Pro Asn Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6969 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6969 tccaagaaca cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aagattttcc cgtttatcgc gcaccccgcc caaatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6970 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6970 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Asp Phe Pro Val Tyr Arg Ala Pro 20 25 30 Arg Pro Asn Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6971 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6971 Cys Thr His Val Arg Ser Pro Ser Met Gly Ala Phe Trp Ile Trp 1 5 10 15 <210> 6972 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6972 accaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacat atttctgtac acacgtccgt tctccgagca tgggtgcttt ttggatctgg 120 ggccaaggg 129 <210> 6973 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6973 Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Phe Cys Thr His Val Arg Ser Pro 20 25 30 Ser Met Gly Ala Phe Trp Ile Trp Gly Gln Gly 35 40 <210> 6974 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6974 accaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgcggac 60 acagccacat atttctgtac acacgtccgt tctccgagca tgggtgcttt ttggatctgg 120 ggccaaggg 129 <210> 6975 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6975 Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Ala Asp Thr Ala Thr Tyr Phe Cys Thr His Val Arg Ser Pro 20 25 30 Ser Met Gly Ala Phe Trp Ile Trp Gly Gln Gly 35 40 <210> 6976 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6976 Cys Ala Arg Glu Pro Ile Gln Leu Trp Leu Leu Pro Trp Ser Gly Ala 1 5 10 15 Asp Tyr Trp <210> 6977 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6977 tccatcagca cagcctacat ggagctgagc aggctgagat ctgacgacac ggccgtgtat 60 tactgtgcga gagagccaat acagctatgg ttactcccct ggtccggagc ggactactgg 120 ggccaggga 129 <210> 6978 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6978 Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg Ser Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Ile Gln Leu Trp Leu Leu 20 25 30 Pro Trp Ser Gly Ala Asp Tyr Trp Gly Gln Gly 35 40 <210> 6979 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6979 tccatcagca cagcctacat ggagctgagc aggctgagat ctgacgacac agccgtgtat 60 tactgtgcga gagagccaat acagctatgg ttactcccct ggtccggagc ggactactgg 120 ggccaggga 129 <210> 6980 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6980 Cys Ala Arg Thr Lys Trp Phe Gly Glu Phe Pro Phe Asp Tyr Trp 1 5 10 15 <210> 6981 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6981 ctccaagaca cctccaaaag ccaggtggtc cttaccatga ccaacatgga ccctgtggac 60 acagccacat attactgtgc acggacaaaa tggttcgggg agtttccttt tgactactgg 120 ggccaggga 129 <210> 6982 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6982 Leu Gln Asp Thr Ser Lys Ser Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Thr Lys Trp Phe 20 25 30 Gly Glu Phe Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6983 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6983 tccaaggaca cctccaaaag ccaggtggtc cttaccatga ccaacatgga ccctgtggac 60 acagccacat attactgtgc acggacaaaa tggttcgggg agtttccttt tgactactgg 120 ggccaggga 129 <210> 6984 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6984 Ser Lys Asp Thr Ser Lys Ser Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Thr Lys Trp Phe 20 25 30 Gly Glu Phe Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6985 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6985 Cys Ala Arg Val Leu Ser Thr Phe Gly Gly Val Gly Ala Phe Asp Ile 1 5 10 15 Trp <210> 6986 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6986 gacgcatccg cgagcacagc ctacatggag ctgagcagcc tgagatctga agacacggct 60 gtgtattact gtgcgagagt cttgagtaca tttgggggag ttggggcttt tgatatctgg 120 ggccaaggg 129 <210> 6987 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6987 Asp Ala Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Leu Ser Thr Phe Gly 20 25 30 Gly Val Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6988 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6988 gacacatccg cgagcacagc ctacatggag ctgagcagcc tgagatctga agacacggct 60 gtgtattact gtgcgagagt cttgagtaca tttgggggag ttggggcttt tgatatctgg 120 ggccaaggg 129 <210> 6989 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6989 Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Leu Ser Thr Phe Gly 20 25 30 Gly Val Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6990 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6990 Cys Ala Arg Asp Gly Tyr Tyr Tyr Asp Ser Ser Gly Ser Asp Ala Phe 1 5 10 15 Asp Ile Trp <210> 6991 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6991 tccaagaact cgctgtatct tcaaatgaac agcctgagag ccgaggacac ggccgtgtat 60 tactgtgcga gagatgggta ttactatgat agtagtggct ccgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6992 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6992 Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Asp Gly Tyr Tyr Tyr Asp Ser Ser 20 25 30 Gly Ser Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6993 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6993 tccaagaaca cgctgtatct tcaaatgaac agcctgagag ccgaggacac ggccgtgtat 60 tactgtgcga gagatgggta ttactatgat agtagtggct ccgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 6994 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6994 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Asp Gly Tyr Tyr Tyr Asp Ser Ser 20 25 30 Gly Ser Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 6995 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6995 Cys Ala Arg Gly Leu Ser Ser Trp Glu Pro Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 6996 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6996 ccagacacat ccaagaacca gttctccctg cagctgaact ctgtgactcc cgaggacacg 60 gctgtgtatt actgtgcaag aggtctcagc agctgggaac cttactactt tgactactgg 120 ggccaggga 129 <210> 6997 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6997 Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser Val Thr 1 5 10 15 Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Leu Ser Ser Trp 20 25 30 Glu Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 6998 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6998 ccagacacat ccaagaacca gttctccctg cagctgaact ctgtgactcc cgaggacacg 60 gctgtgtatt actgtgcaag aggtctcagc agctgggaac cttactactt tgactactgg 120 gaccaggga 129 <210> 6999 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 6999 Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser Val Thr 1 5 10 15 Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Leu Ser Ser Trp 20 25 30 Glu Pro Tyr Tyr Phe Asp Tyr Trp Asp Gln Gly 35 40 <210> 7000 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7000 Cys Ala Ser Gln Tyr Thr Gly Tyr Asp Tyr Phe Asp Tyr Trp 1 5 10 <210> 7001 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7001 ttctccttgg acacctctgt cagcacggca tatctgcaga tcagcagcct aaaggctgag 60 gacactgccg tgtattactg tgcgagtcaa tatactggct acgattactt tgactactgg 120 ggtcaggga 129 <210> 7002 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7002 Phe Ser Leu Asp Thr Ser Val Ser Thr Ala Tyr Leu Gln Ile Ser Ser 1 5 10 15 Leu Lys Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gln Tyr Thr 20 25 30 Gly Tyr Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7003 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7003 ttctccttag acacctctgt cagcacggca tatctgcaga tcagcagcct aaaggctgag 60 gacactgccg tgtattattg tgcgagtcaa tatactggct acgattactt tgactactgg 120 ggtcaggga 129 <210> 7004 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7004 Cys Ala Arg Asp Asp Tyr Ser Asp Tyr Arg Pro Phe Asp Tyr Trp 1 5 10 15 <210> 7005 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7005 accacagaca cgtccacgac cacagcctac atggaactga agaacctgag atctgacgac 60 acggccgttt attactgtgc gagagatgac tacagtgact accgcccatt tgactactgg 120 ggccaggga 129 <210> 7006 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7006 Thr Thr Asp Thr Ser Thr Thr Thr Ala Tyr Met Glu Leu Lys Asn Leu 1 5 10 15 Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Asp Tyr Ser 20 25 30 Asp Tyr Arg Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7007 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7007 accacagaca cgcccacgac cacagcctac atggaactga agaacctgag atctgacgac 60 acggccgttt attactgtgc gagagatgac tacagtgact accgcccatt tgactactgg 120 ggccaggga 129 <210> 7008 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7008 Thr Thr Asp Thr Pro Thr Thr Thr Ala Tyr Met Glu Leu Lys Asn Leu 1 5 10 15 Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Asp Tyr Ser 20 25 30 Asp Tyr Arg Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7009 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7009 Cys Ala Ile Ser Phe Tyr Cys Thr Gly Gly Val Cys Tyr Leu Pro Arg 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 7010 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7010 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gatctcgttc 60 tattgtactg gtggtgtatg ctatttgcct cggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7011 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7011 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Ile Ser Phe Tyr Cys Thr Gly Gly Val Cys Tyr Leu Pro Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7012 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7012 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gatctcgttc 60 tattgtactg gtggtgtatg ctatttgcct cggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7013 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7013 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Ile Ser Phe Tyr Cys Thr Gly Gly Val Cys Tyr Leu Pro Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7014 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7014 Cys Ala His Thr Pro Tyr Asp Phe Trp Ser Gly Tyr Gly Gly Phe Gly 1 5 10 15 Trp Phe Asp Pro Trp 20 <210> 7015 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7015 aaccaggtgg tccttacaat gaccaacatg gaccctgtgg acacagccac atattactgt 60 gcacacaccc cgtacgattt ttggagtggt tatggtgggt ttgggtggtt cgacccctgg 120 ggccaggga 129 <210> 7016 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7016 Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala 1 5 10 15 Thr Tyr Tyr Cys Ala His Thr Pro Tyr Asp Phe Trp Ser Gly Tyr Gly 20 25 30 Gly Phe Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7017 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7017 aaaccaggtg gtcctacaat gaccaacatg gaccctgtgg acacagccac atattactgt 60 gcacacaccc cgtacgattt ttggagtggt tatggtgggt ttgggtggtt cgacccctgg 120 ggccaggga 129 <210> 7018 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7018 Lys Pro Gly Gly Pro Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala 1 5 10 15 Thr Tyr Tyr Cys Ala His Thr Pro Tyr Asp Phe Trp Ser Gly Tyr Gly 20 25 30 Gly Phe Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7019 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7019 Cys Ala Arg Leu Ala Ala Ala Ala Ala Gly Pro Tyr Gly Met Asp Val 1 5 10 15 Trp <210> 7020 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7020 gacacgtcca cgagcacagt ctacatggag ctgagcagcc tgagatctga ggacacggcc 60 gtgtattact gtgcgaggct agcagcagct gctgccggac cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7021 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7021 Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Ala Ala Ala Ala Ala 20 25 30 Gly Pro Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7022 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7022 gacacgccca cgagcactgt ctacatggag ctgagcagcc tgagatctga ggacacggcc 60 gtgtattact gtgcgaggct agcagcagct gctgccggac cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7023 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7023 Asp Thr Pro Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Ala Ala Ala Ala Ala 20 25 30 Gly Pro Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7024 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7024 Cys Ala Lys Trp Arg Met Val Gln Gly Val Glu Thr Asp Tyr Trp 1 5 10 15 <210> 7025 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7025 tccagagaca attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaatggcgt atggttcagg gagttgaaac tgactactgg 120 ggccaggga 129 <210> 7026 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7026 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Trp Arg Met Val 20 25 30 Gln Gly Val Glu Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 7027 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7027 tccagacaca attccaacaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaatggcgt atggttcagg gagttgaaac tgactactgg 120 ggccaggga 129 <210> 7028 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7028 Ser Arg His Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Trp Arg Met Val 20 25 30 Gln Gly Val Glu Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 7029 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7029 Cys Ala Arg Ala Pro Tyr Ser Ser Ser Phe Asp Tyr Trp 1 5 10 <210> 7030 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7030 accatatcag tagacacgtc caagaaccag ttctccctga agctgagctc tgtgaccgcc 60 gcggacacgg ctgtgtatta ctgtgcgaga gcaccctata gcagcagctt tgactactgg 120 ggccaggga 129 <210> 7031 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7031 Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Pro 20 25 30 Tyr Ser Ser Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7032 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7032 accatatcag tagacacgcc caagaaccag ttctccctga agctgagctc tgtgaccgcc 60 gcggacacgg ctgtgtatta ctgtgcgaga gcaccctata gcagcagctt tgactactgg 120 ggccaggga 129 <210> 7033 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7033 Thr Ile Ser Val Asp Thr Pro Lys Asn Gln Phe Ser Leu Lys Leu Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Pro 20 25 30 Tyr Ser Ser Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7034 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7034 Cys Ala Ser Gly Pro Asn Ser Gly Ser Tyr Trp Tyr Tyr Trp 1 5 10 <210> 7035 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7035 ttgaccaggg acacgtccac gagcacagtc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagcggt cctaatagtg ggagctactg gtactactgg 120 ggccaggga 129 <210> 7036 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7036 Leu Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly Pro Asn 20 25 30 Ser Gly Ser Tyr Trp Tyr Tyr Trp Gly Gln Gly 35 40 <210> 7037 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7037 atgaccaggg acacgtccac gagcacagtc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagcggt cctaatagtg ggagctactg gtactactgg 120 ggccaggga 129 <210> 7038 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7038 Met Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly Pro Asn 20 25 30 Ser Gly Ser Tyr Trp Tyr Tyr Trp Gly Gln Gly 35 40 <210> 7039 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7039 Cys Ala Ser Gly Glu Gln Gln Leu Val Gly Gly Asp Tyr Phe Asp Tyr 1 5 10 15 Trp <210> 7040 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7040 gacaacgcca agaactcact gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgcgagtgg ggagcagcag ttggtaggag gggactactt tgactactgg 120 ggccaggga 129 <210> 7041 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7041 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Gly Glu Gln Gln Leu Val 20 25 30 Gly Gly Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7042 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7042 gacaacgcca agaactcact gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgcgagtgg ggagcagcag ctggtaggag gggactactt tgactactgg 120 ggccaggga 129 <210> 7043 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7043 Cys Ala Lys Glu Gly Asp Val Tyr Tyr Asp Tyr Val Trp Gly Ser Tyr 1 5 10 15 Glu Leu Asp Tyr Trp 20 <210> 7044 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7044 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagagg gcgacgtgta ttatgattac gtttggggga gttatgaact tgactactgg 120 ggccaggga 129 <210> 7045 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7045 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Glu Gly Asp Val Tyr Tyr Asp Tyr Val Trp 20 25 30 Gly Ser Tyr Glu Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7046 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7046 aacacgatgt atctgcaaat caacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagagg gcgacgtgta ttatgattac gtttggggga gttatgaact tgactactgg 120 ggccaggga 129 <210> 7047 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7047 Asn Thr Met Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Glu Gly Asp Val Tyr Tyr Asp Tyr Val Trp 20 25 30 Gly Ser Tyr Glu Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7048 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7048 Cys Ala Arg Gly Gly Gly Asn Gly Trp Arg Ser Glu Gly Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 7049 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7049 actgtctact tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agaggtggag gtaatggctg gcgaagcgaa ggctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7050 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7050 Thr Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Gly Gly Asn Gly Trp Arg Ser Glu Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7051 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7051 acagtctaca tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agaggtggag gtaatggctg gcgaagcgaa ggctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7052 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7052 Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Gly Gly Asn Gly Trp Arg Ser Glu Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7053 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7053 Cys Ala Arg Asp Leu Lys Asp Ile Val Val Val Val Ala Ala Val His 1 5 10 15 Asp Ala Phe Asp Ile Trp 20 <210> 7054 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7054 acagcctact tggagctgag gagcctgaga tctgacgaca cggccgtgta ttactgtgcg 60 agagatctca aggatattgt agtggtggta gctgctgtcc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7055 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7055 Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Leu Lys Asp Ile Val Val Val Val Ala Ala 20 25 30 Val His Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7056 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7056 acagcctaca tggagctgag gagcctgaga tctgacgaca cggccgtgta ttactgtgcg 60 agagatctca aggatattgt agtggtggta gctgctgtcc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7057 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7057 Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Leu Lys Asp Ile Val Val Val Val Ala Ala 20 25 30 Val His Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7058 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7058 Cys Ala Arg Arg Gly Ala Tyr Ser Gly Ser Phe Arg Thr Trp Ala Phe 1 5 10 15 Asp Ile Trp <210> 7059 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7059 tccaagaacc agttctccct gaagctgagc tctgtgaccg ccgcagacac ggctgtgtat 60 tactgtgcga gacgtggcgc ttattccggt tcgttccgca catgggcttt tgatatctgg 120 ggccaaggg 129 <210> 7060 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7060 Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Arg Gly Ala Tyr Ser Gly Ser Phe 20 25 30 Arg Thr Trp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7061 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7061 tccaagaacc agttctccct gaagccgagc tctgtgaccg ccgcagacac ggctgtgtat 60 tactgtgcga gacgtggcgc ttattccggt tcgttccgca catgggcttt tgatatctgg 120 ggccaaggg 129 <210> 7062 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7062 Ser Lys Asn Gln Phe Ser Leu Lys Pro Ser Ser Val Thr Ala Ala Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Arg Gly Ala Tyr Ser Gly Ser Phe 20 25 30 Arg Thr Trp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7063 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7063 Cys Ala Arg Asp Val Tyr Tyr Gly Ser Gly Ser Tyr Tyr Trp Phe Asp 1 5 10 15 Pro Trp <210> 7064 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7064 aaatccacga gcacagtcta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagagatgt gtactatggt tcggggagtt attactggtt cgacccctgg 120 ggccaggga 129 <210> 7065 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7065 Lys Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Val Tyr Tyr Gly Ser Gly 20 25 30 Ser Tyr Tyr Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7066 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7066 aaatccacga gcacagccta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgagagatgt gtactatggt tcggggagtt attactggtt cgacccctgg 120 ggccaggga 129 <210> 7067 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7067 Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Val Tyr Tyr Gly Ser Gly 20 25 30 Ser Tyr Tyr Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7068 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7068 Cys Ala Arg Asp Leu Ala Ser Arg Gln Gln Leu Val Leu Ile Gly Tyr 1 5 10 15 Trp Asn Tyr Phe Asp Tyr Trp 20 <210> 7069 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7069 ctgtatctgc aaatgaacag tctgagagcc gaggacacgg ccttgtatta ctgtgcgaga 60 gatctagcaa gtaggcagca gctggtactg atcgggtatt ggaactactt tgactactgg 120 ggccagggg 129 <210> 7070 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7070 Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr 1 5 10 15 Tyr Cys Ala Arg Asp Leu Ala Ser Arg Gln Gln Leu Val Leu Ile Gly 20 25 30 Tyr Trp Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7071 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7071 ctgtatctgc aaatgaacag tctgagagcc gaggacacgg ccttgtatta ctgtgcgaga 60 gatctagcaa gtaggcagca gctggtactg atcgggtatt ggaactactt tgactactgg 120 ggccaggga 129 <210> 7072 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7072 Cys Ala Arg Gly Trp His Ala Lys Asn Asp Ala Phe Asp Ile Trp 1 5 10 15 <210> 7073 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7073 tcagttgact cgtccaagaa ccagttctcc ctgaagctga gctctgtgac cgccgcggac 60 acggccgtgt attactgtgc gagagggtgg catgctaaaa atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7074 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7074 Ser Val Asp Ser Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Trp His Ala 20 25 30 Lys Asn Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7075 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7075 tcagtagaca cgtccaagaa ccagttctcc ctgaagctga gctctgtgac cgccgcggac 60 acggccgtgt attactgtgc gagagggtgg catgctaaaa atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7076 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7076 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Trp His Ala 20 25 30 Lys Asn Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7077 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7077 Cys Ala Arg Asp Arg Leu Ser Trp Gly Arg Tyr Phe Asp Leu Trp 1 5 10 15 <210> 7078 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7078 tccagagaca attccaagaa cacgctgtat cttcaaatga acagcctgag agccgaggac 60 acggccgtgt attactgtgc gagagaccgg ctttcctggg gacggtactt cgatctctgg 120 ggccgtggc 129 <210> 7079 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7079 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Leu Ser 20 25 30 Trp Gly Arg Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 7080 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7080 tacagagaca attccaagaa cacgctgtat cttcaaatga acagcctgag agccgaggac 60 acggccgtgt attactgtgc gagagaccgg ctttcctggg gacggtactt cgatctctgg 120 ggccgtagc 129 <210> 7081 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7081 Tyr Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Leu Ser 20 25 30 Trp Gly Arg Tyr Phe Asp Leu Trp Gly Arg Ser 35 40 <210> 7082 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7082 Cys Ala Arg His Thr Leu Ala Gln Leu Trp Phe Gly Asp Tyr Gly Met 1 5 10 15 Asp Val Trp <210> 7083 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7083 tccatcagca cagcctacat ggagctgagc gggctgagat ctgacgacac ggccgtgtat 60 tactgtgcga gacatacctt agcccaatta tggttcgggg actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7084 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7084 Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Gly Leu Arg Ser Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg His Thr Leu Ala Gln Leu Trp Phe 20 25 30 Gly Asp Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7085 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7085 tccatcagca cagcctacat ggagctgagc aggctgagat ctgacgacac ggccgtgtat 60 tactgtgcga gacatacctt agcccaatta tggttcgggg actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7086 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7086 Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg Ser Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg His Thr Leu Ala Gln Leu Trp Phe 20 25 30 Gly Asp Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7087 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7087 Cys Ala Arg Ile Thr Trp Phe Gly Glu Leu Tyr Asn Gly Met Asp Val 1 5 10 15 Trp <210> 7088 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7088 gacacctcca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acgtattact gtgcacggat aacatggttc ggggagttat ataacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7089 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7089 Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Thr Trp Phe Gly Glu 20 25 30 Leu Tyr Asn Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7090 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7090 ggacacctcc aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acgtattact gtgcacggat aacatggttc ggggagttat ataacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7091 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7091 Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Thr Trp Phe Gly Glu 20 25 30 Leu Tyr Asn Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7092 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7092 Cys Ala Arg Gly His Gln Ser Gly Tyr Asn Tyr Tyr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 7093 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7093 aagaaccagt tctccctgaa gctgagcttt gtgaccgccg cggacacggc tgtgtattac 60 tgtgcgagag ggcatcaaag tggctacaac tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7094 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7094 Lys Asn Gln Phe Ser Leu Lys Leu Ser Phe Val Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly His Gln Ser Gly Tyr Asn Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7095 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7095 aagaaccagt tctccctgaa gctgagctct gtgaccgccg cggacacggc tgtgtattac 60 tgtgcgagag ggcatcaaag tggctacaac tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7096 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7096 Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly His Gln Ser Gly Tyr Asn Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7097 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7097 Cys Ala Arg Gly Val Tyr Ser Phe Asp Phe Trp 1 5 10 <210> 7098 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7098 cgagttacca tgtcagtaga cacgtctaag aaccagttct ccctgaagtt gagctctgtg 60 actgccgcgg acgcggccgt gtattactgt gcgagagggg tctacagctt tgacttctgg 120 ggccaggga 129 <210> 7099 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7099 Arg Val Thr Met Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys 1 5 10 15 Leu Ser Ser Val Thr Ala Ala Asp Ala Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Gly Val Tyr Ser Phe Asp Phe Trp Gly Gln Gly 35 40 <210> 7100 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7100 cgagttacca tgtcagtaga cacgtctaag aaccagttct ccctgaagct gagctctgtg 60 actgccgcgg acgcggccgt gtattactgt gcgagagggg tctacagctt cgacttctgg 120 ggccaggga 129 <210> 7101 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7101 Cys Ala His Lys Ser Leu Ser Tyr Tyr Asn Val Gly Trp Phe Asp Pro 1 5 10 15 Trp <210> 7102 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7102 gacacctcca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacaa gtccctaagt tattataacg tcgggtggtt cgacccctgg 120 ggccaggga 129 <210> 7103 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7103 Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Lys Ser Leu Ser Tyr Tyr 20 25 30 Asn Val Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7104 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7104 gacaccccca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacaa gtccctaagt tattataacg tcgggtggtt cgacccctgg 120 ggtcaggga 129 <210> 7105 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7105 Asp Thr Pro Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Lys Ser Leu Ser Tyr Tyr 20 25 30 Asn Val Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7106 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7106 Cys Ala His Lys Val Ser Val Val Arg Gly Val Ile Asn Tyr Trp 1 5 10 15 <210> 7107 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7107 caccaaggac acctccaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacat attactgtgc acacaaagtt tctgtggttc ggggagttat caactactgg 120 ggccaggga 129 <210> 7108 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7108 His Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Lys Val Ser Val 20 25 30 Val Arg Gly Val Ile Asn Tyr Trp Gly Gln Gly 35 40 <210> 7109 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7109 accaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacat attactgtgc acacaaagtt tctgtggttc ggggagttat caactactgg 120 ggccaggga 129 <210> 7110 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7110 Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Lys Val Ser Val 20 25 30 Val Arg Gly Val Ile Asn Tyr Trp Gly Gln Gly 35 40 <210> 7111 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7111 Cys Ala Arg Gly Ser Ser Ser Ser Gly His His Tyr Trp 1 5 10 <210> 7112 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7112 tacatatcag tagacacgtc caagaaccag ttctccctga agctgagctc tgtgaccgcc 60 gcggacacgg ctgtgtatta ctgtgcgaga ggctcatcaa gcagtggcca tcattactgg 120 ggccaggga 129 <210> 7113 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7113 Tyr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Ser 20 25 30 Ser Ser Ser Gly His His Tyr Trp Gly Gln Gly 35 40 <210> 7114 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7114 accatatcag tagacacgtc caagaaccag ttctccctga agctgagctc tgtgaccgcc 60 gcggacacgg ctgtgtatta ctgtgcgaga ggctcatcaa gcagtggcca tcattactgg 120 ggccaggga 129 <210> 7115 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7115 Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Ser 20 25 30 Ser Ser Ser Gly His His Tyr Trp Gly Gln Gly 35 40 <210> 7116 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7116 Cys Ala Ser Glu Gly Gly Thr Ile Cys Ser Ser Thr Ser Cys Pro Leu 1 5 10 15 Gly Tyr Tyr Gly Met Asp Val Trp 20 <210> 7117 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7117 tatctgcaaa tgaacagcct gagagccgag gacacggccg tatattactg tgcctccgag 60 ggggggacta tttgtagtag taccagctgc cccctcggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7118 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7118 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Ser Glu Gly Gly Thr Ile Cys Ser Ser Thr Ser Cys Pro Leu 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7119 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7119 tatatgcaaa tcaacagcct gagagccgag gacacggccg tatattactg tgcctccgag 60 ggggggacta tttgtagtag taccagctgc cccctcggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7120 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7120 Tyr Met Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Ser Glu Gly Gly Thr Ile Cys Ser Ser Thr Ser Cys Pro Leu 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7121 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7121 Cys Ala Lys Asp Arg Gly His Leu Pro Asn Asp Gly Ser Asp Tyr Trp 1 5 10 15 <210> 7122 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7122 agagacaaca cccagaactc cctctttctg caaatgaaca gtctgagagc ggaagacacg 60 gccttctatt attgtgcgaa agacaggggg cacttaccaa acgacgggtc tgactactgg 120 ggccaggga 129 <210> 7123 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7123 Arg Asp Asn Thr Gln Asn Ser Leu Phe Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Phe Tyr Tyr Cys Ala Lys Asp Arg Gly His Leu 20 25 30 Pro Asn Asp Gly Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 7124 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7124 agagacaaca cccagaactc cctctttctg caaatgaaca gtctgagagc ggaagacacg 60 gcctcctatt attgtgcgaa agacaggggg cacttaccaa acgacgggtc tgactactgg 120 ggccaggga 129 <210> 7125 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7125 Arg Asp Asn Thr Gln Asn Ser Leu Phe Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Ser Tyr Tyr Cys Ala Lys Asp Arg Gly His Leu 20 25 30 Pro Asn Asp Gly Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 7126 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7126 Cys Ala Arg Asp Gln Gly Gly Ala Gly Pro Thr Thr Val Asp Tyr Trp 1 5 10 15 <210> 7127 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7127 cgagacaacg ccaagaacac gctgtatctg gaaatgaaca gtctgggagc cgaggacacg 60 gctgtgtatt actgtgcaag agatcagggg ggagcgggac ctacaaccgt agactactgg 120 ggccaggga 129 <210> 7128 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7128 Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Glu Met Asn Ser Leu Gly 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Gln Gly Gly Ala 20 25 30 Gly Pro Thr Thr Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 7129 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7129 cgagacaacg ccaagaacac gctgtatctg caaatgaaca gtctgggagc cgaggacacg 60 gctgtgtatt actgtgcaag agatcagggg ggagcgggac ctacaaccgt agactactgg 120 ggccaggga 129 <210> 7130 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7130 Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Gly 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Gln Gly Gly Ala 20 25 30 Gly Pro Thr Thr Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 7131 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7131 Cys Ala His Ser Thr Pro Asp Tyr Phe Asp Tyr Trp 1 5 10 <210> 7132 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7132 ctcaccatca ccaaggacac ctccaaaaac cagttggtcc ttacaatgac caacatggac 60 cctgtggaca caggcacgta ttactgtgca cacagtaccc cggactactt tgactactgg 120 ggccaggga 129 <210> 7133 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7133 Leu Thr Ile Thr Lys Asp Thr Ser Lys Asn Gln Leu Val Leu Thr Met 1 5 10 15 Thr Asn Met Asp Pro Val Asp Thr Gly Thr Tyr Tyr Cys Ala His Ser 20 25 30 Thr Pro Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7134 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7134 ctcaccatca ccaaggacac ctccaaaaac cagttggtcc ttacaatgac caacatggac 60 cctgtggaca caggcacata ttactgtgca cacagtaccc cggactactt tgactactgg 120 ggccaggga 129 <210> 7135 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7135 Cys Ala Lys Leu Lys Ala Phe Asp Met Trp 1 5 10 <210> 7136 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7136 ggccggttca ccatctcaag agacaattcc aagaacacgg tgtatctgca aatgaacagc 60 ctgagagccg aggacacggc cgtatattac tgtgcgaaac tgaaggcttt tgatatgtgg 120 ggccaaggg 129 <210> 7137 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7137 Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Val Tyr Leu 1 5 10 15 Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Lys Leu Lys Ala Phe Asp Met Trp Gly Gln Gly 35 40 <210> 7138 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7138 ggccggttca ccatctcaag acacaattcc aagaacacgg tgtatctgca aatgaacagc 60 ctgagagccg aggacacggc cgtatattac tgtgcgaaac tgaaggcttt tgatatgtgg 120 ggccaaggg 129 <210> 7139 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7139 Gly Arg Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Val Tyr Leu 1 5 10 15 Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Lys Leu Lys Ala Phe Asp Met Trp Gly Gln Gly 35 40 <210> 7140 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7140 Cys Ala Lys Asp Gly Gly Ser Gly Thr Arg Val Tyr Tyr Tyr Gly Ser 1 5 10 15 Gly Ser Tyr Phe Ile Asp Tyr Trp 20 <210> 7141 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7141 tatctgcaaa tgaacagcct gagagccgag gacacggccg tatattactg tgcgaaagat 60 ggtggaagtg gaacgagggt gtattactat ggttcgggga gttattttat tgactactgg 120 ggccaggga 129 <210> 7142 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7142 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Gly Gly Ser Gly Thr Arg Val Tyr Tyr Tyr Gly Ser 20 25 30 Gly Ser Tyr Phe Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 7143 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7143 tatatgaaaa tgaacagcct gagagccgag gacacggccg tatattactg tgcgaaagat 60 ggtggaagtg gaacgagggt gtattactat ggttcgggga gttattttat tgactactgg 120 ggccaggga 129 <210> 7144 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7144 Tyr Met Lys Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Gly Gly Ser Gly Thr Arg Val Tyr Tyr Tyr Gly Ser 20 25 30 Gly Ser Tyr Phe Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 7145 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7145 Cys Ala Arg Gly Trp Ala Pro Asp Tyr Trp 1 5 10 <210> 7146 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7146 tgtcgagtca ccatatcgat ggacacgtcc aagaaccaat tctccctgaa cctgaattct 60 gtgaccgccg cggacacggc tgtatattac tgtgcgagag gttgggcacc tgactactgg 120 ggccaggga 129 <210> 7147 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7147 Cys Arg Val Thr Ile Ser Met Asp Thr Ser Lys Asn Gln Phe Ser Leu 1 5 10 15 Asn Leu Asn Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Arg Gly Trp Ala Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 7148 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7148 agtcgagtca ccatatcgat ggacacgtcc aagaaccaat tctccctgaa cctgaattct 60 gtgaccgccg cggacacggc tgtatattac tgtgcgagag gttgggcacc tgactactgg 120 ggccaggga 129 <210> 7149 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7149 Ser Arg Val Thr Ile Ser Met Asp Thr Ser Lys Asn Gln Phe Ser Leu 1 5 10 15 Asn Leu Asn Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Arg Gly Trp Ala Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 7150 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7150 Cys Ala Arg Val Gly Gly Ile Ala Ala Ala Gly Asn Ile Leu Leu Ser 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 7151 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7151 actgcctact tggagctgag gagcctgaga tctgacgaca cggccgtgta ttactgtgcg 60 agagttggag gtatagcagc agctggtaac atcttgctgt cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7152 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7152 Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Val Gly Gly Ile Ala Ala Ala Gly Asn Ile Leu 20 25 30 Leu Ser Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7153 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7153 acagcctaca tggagctgag gagcctgaga tctgacgaca cggccgtgta ttactgtgcg 60 agagttggag gtatagcagc agctggtaac atcttgctgt cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7154 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7154 Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Val Gly Gly Ile Ala Ala Ala Gly Asn Ile Leu 20 25 30 Leu Ser Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7155 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7155 Cys Ala Lys Asp Thr Ser Ser Gly Trp Tyr Gly Pro Leu Ser Tyr Trp 1 5 10 15 <210> 7156 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7156 agagacaacg ccaagaactc cctgtatctg caaatgaaca gtctgagagc tgatgacact 60 gccttgtatt actgtgcaaa agacactagc agtggctggt acggccccct ttcctactgg 120 ggccaggga 129 <210> 7157 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7157 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Asp Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Thr Ser Ser Gly 20 25 30 Trp Tyr Gly Pro Leu Ser Tyr Trp Gly Gln Gly 35 40 <210> 7158 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7158 agagacaacg ccaagaactc cctgtatctg caaatgaaca gtctgagagc tgaggacacg 60 gccttgtatt actgtgcaaa agacactagc agtggctggt acggccccct ttcctactgg 120 ggccaggga 129 <210> 7159 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7159 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Thr Ser Ser Gly 20 25 30 Trp Tyr Gly Pro Leu Ser Tyr Trp Gly Gln Gly 35 40 <210> 7160 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7160 Cys Ala Arg Gly Arg Gly Ser Val Val Val Pro Ala Asp Thr Thr Ser 1 5 10 15 Thr Tyr Tyr Gly Met Asp Val Trp 20 <210> 7161 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7161 tccctgaagc tgggctctgt gaccgccgcg gacacggctg tgtattactg tgcgagaggc 60 cgggggagtg tagtagtacc agctgacacc acatctactt actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7162 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7162 Ser Leu Lys Leu Gly Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Gly Arg Gly Ser Val Val Val Pro Ala Asp Thr Thr Ser 20 25 30 Thr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7163 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7163 tccctgaagc tgagctctgt gaccgccgcg gacacggctg tgtattactg tgcgagaggc 60 cgggggagtg tagtagtacc agctgacacc acatctactt actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7164 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7164 Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Gly Arg Gly Ser Val Val Val Pro Ala Asp Thr Thr Ser 20 25 30 Thr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7165 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7165 Cys Ala Thr Asp Leu Asp Gly Asp Tyr Lys Phe Asp Tyr Trp 1 5 10 <210> 7166 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7166 ttatcggtag acacgtccac gaaccagttc tccctgaaga tgagctctct gaccgccgcg 60 gacacggccg tgtatcactg cgcgacagat ctggacggtg actacaaatt tgactactgg 120 ggccaggga 129 <210> 7167 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7167 Leu Ser Val Asp Thr Ser Thr Asn Gln Phe Ser Leu Lys Met Ser Ser 1 5 10 15 Leu Thr Ala Ala Asp Thr Ala Val Tyr His Cys Ala Thr Asp Leu Asp 20 25 30 Gly Asp Tyr Lys Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7168 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7168 atatcggtag acacgtccaa gaaccagttc tccctgaaga tgagctctct gaccgccgcg 60 gacacggccg tgtatcactg cgcgacagat ctggacggtg actacaaatt tgactactgg 120 ggccaggga 129 <210> 7169 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7169 Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Met Ser Ser 1 5 10 15 Leu Thr Ala Ala Asp Thr Ala Val Tyr His Cys Ala Thr Asp Leu Asp 20 25 30 Gly Asp Tyr Lys Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7170 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7170 Cys Ala Arg Asp Asp Glu Gly Gln His Tyr Phe Asp Tyr Trp 1 5 10 <210> 7171 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7171 atctccaggg acaacgccaa gaactcactg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagat gatgagggtc agcactactt tgactactgg 120 ggccaggga 129 <210> 7172 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7172 Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Asp Glu 20 25 30 Gly Gln His Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7173 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7173 atctccaggc acaaccccaa gaactcactg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagat gatgagggtc agcactactt tgactactgg 120 ggccaggga 129 <210> 7174 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7174 Ile Ser Arg His Asn Pro Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Asp Glu 20 25 30 Gly Gln His Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7175 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7175 Cys Ala Arg Ser Gly Val Ile Gly Lys Tyr Asp Ser Ser Pro Asn Asp 1 5 10 15 Ala Phe Asp Ile Trp 20 <210> 7176 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7176 aacacgctgt atcttcaaat gaacagcctg agagccgagg acacggccgt gtattactgt 60 gcgagatcag gggtaatagg gaagtatgat agtagcccaa atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7177 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7177 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Ser Gly Val Ile Gly Lys Tyr Asp Ser Ser 20 25 30 Pro Asn Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7178 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7178 aacacgctgt atattcaaat gaacagcctg agagccgagg acacggccgt gtattactgt 60 gcgagatcag gtgtaatagg gaagtatgat agtagcccaa atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7179 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7179 Asn Thr Leu Tyr Ile Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Ser Gly Val Ile Gly Lys Tyr Asp Ser Ser 20 25 30 Pro Asn Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7180 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7180 Cys Ala His Thr Thr Asn Gly Ile Leu Thr Gly Tyr Tyr Pro Asp Tyr 1 5 10 15 Tyr Tyr Tyr Gly Met Asp Val Trp 20 <210> 7181 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7181 gtccttacaa tgaccagcat ggaccctgtg gacacagcca catattactg tgcacacacc 60 actaacggta ttttgactgg ttattatccg gactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7182 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7182 Val Leu Thr Met Thr Ser Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr 1 5 10 15 Cys Ala His Thr Thr Asn Gly Ile Leu Thr Gly Tyr Tyr Pro Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7183 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7183 gtccttacaa tgaccaacat ggaccctgtg gacacagcca catattactg tgcacacacc 60 actaacggta ttttgactgg ttattatccg gactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7184 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7184 Val Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr 1 5 10 15 Cys Ala His Thr Thr Asn Gly Ile Leu Thr Gly Tyr Tyr Pro Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7185 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7185 Cys Val Arg Glu Asp Leu Asn Thr Pro Ser Phe Asp Leu Trp 1 5 10 <210> 7186 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7186 ttctccaggg acgacgccaa gaactctctg tatcttcaaa tcaatagcct gagagccgag 60 gacacggccg tgtatttttg tgtcagagag gacctcaaca cgccaagctt tgacctctgg 120 ggccaggga 129 <210> 7187 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7187 Phe Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr Leu Gln Ile Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Phe Cys Val Arg Glu Asp Leu 20 25 30 Asn Thr Pro Ser Phe Asp Leu Trp Gly Gln Gly 35 40 <210> 7188 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7188 atctccaggg acgacgccaa gaactctctg tatcttcaaa tcaatagcct gagagccgag 60 gacacggccg tgtatttttg tgtcagagag gacctcaaca cgccaagctt tgacctctgg 120 ggccaggga 129 <210> 7189 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7189 Ile Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr Leu Gln Ile Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Phe Cys Val Arg Glu Asp Leu 20 25 30 Asn Thr Pro Ser Phe Asp Leu Trp Gly Gln Gly 35 40 <210> 7190 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7190 Cys Ala Arg Asp Arg Arg Asp Tyr Gly Leu His Phe Asp Tyr Trp 1 5 10 15 <210> 7191 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7191 accgcggaca aatccacgag cacagcctac atggagctga gcagcctgag atctgaggac 60 acggccgtgt attactgtgc gagagatcgg cgagactacg gtctccactt tgactactgg 120 ggccaggga 129 <210> 7192 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7192 Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Arg Asp 20 25 30 Tyr Gly Leu His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7193 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7193 accgcgcaca aatccacgag cacagcctac atggagctga gcagcctgat atctgaggac 60 acggccgtgt attactgtgc gagagatcgg cgagactacg gtctccactt tgactactgg 120 ggccaggga 129 <210> 7194 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7194 Thr Ala His Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Ile Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Arg Asp 20 25 30 Tyr Gly Leu His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7195 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7195 Cys Ala Lys Asp Gly Ala Ser Gly Trp Pro Asn Trp His Phe Asp Leu 1 5 10 15 Trp <210> 7196 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7196 tataattcca acaacacgct gtatctgcaa atgaacagcc tgagagtcga ggacacggcc 60 gtatattact gtgcgaaaga tggcgccagt ggctggccca actggcattt cgatctctgg 120 ggccgtgga 129 <210> 7197 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7197 Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Val 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Gly Ala Ser Gly Trp 20 25 30 Pro Asn Trp His Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 7198 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7198 gataattcca agaacacgct gtatctgcaa atgaacagcc tgagagtcga ggacacggcc 60 gtatattact gtgcgaaaga tggcgccagt ggctggccca actggcattt cgatctctgg 120 ggccgtgga 129 <210> 7199 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7199 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Val 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Gly Ala Ser Gly Trp 20 25 30 Pro Asn Trp His Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 7200 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7200 Cys Ala Arg Tyr Ser Ser Ser Trp Tyr Glu Glu Gly Gly Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 7201 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7201 aagaactcac tgtatctgca agtgaacagc ctgagagacg aggacacggc tgtgtattac 60 tgtgcgaggt atagcagcag ctggtacgag gaggggggat actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7202 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7202 Lys Asn Ser Leu Tyr Leu Gln Val Asn Ser Leu Arg Asp Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Tyr Ser Ser Ser Trp Tyr Glu Glu Gly 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7203 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7203 aagaactcac tgtatctgca aatgaacagc ctgagagacg aggacacggc tgtgtattac 60 tgtgcgaggt atagcagcag ctggtacgag gaggggggat actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7204 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7204 Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Tyr Ser Ser Ser Trp Tyr Glu Glu Gly 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7205 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7205 Cys Ala Lys Asp Arg Leu Gln Ser Ser Asp Tyr Trp 1 5 10 <210> 7206 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7206 ttcaccatct ccagagacaa ttccaagaat actctgtatc tgcaaatgaa caacctgaga 60 gccgacgaca cggccatata ttactgtgcg aaagatcgcc tacagtcctc agactactgg 120 ggccaggga 129 <210> 7207 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7207 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Asn Leu Arg Ala Asp Asp Thr Ala Ile Tyr Tyr Cys Ala Lys Asp 20 25 30 Arg Leu Gln Ser Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 7208 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7208 ttcaccatct ccagagacaa ttccaagaac actctgtatc tgcaaatgaa caacctgaga 60 gccgacgaca cggccatata ttactgtgcg aaagatcgcc tacagtcctc agactactgg 120 ggccaggga 129 <210> 7209 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7209 Cys Ala Arg Ser Gly Asn Asp Tyr Gly Ser Gly Gly Val Leu Asp Tyr 1 5 10 15 Trp <210> 7210 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7210 gacaagtcca tcagcaccgc ctacctgcag tggagcagcc tgaaggcctc ggacaccgcc 60 atgtattact gtgcgagatc ggggaacgac tatggttcgg ggggagtgct tgactactgg 120 ggccaggga 129 <210> 7211 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7211 Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala 1 5 10 15 Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Ser Gly Asn Asp Tyr Gly 20 25 30 Ser Gly Gly Val Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7212 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7212 gacaagtcca tcaccaccgc ctacttgcag tggagcagcc tgaaggcctc ggacaccgcc 60 atgtattact gtgcgagatc ggggaacgac tatggttcgg ggggagtgct tgactactgg 120 ggccaggga 129 <210> 7213 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7213 Asp Lys Ser Ile Thr Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala 1 5 10 15 Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Ser Gly Asn Asp Tyr Gly 20 25 30 Ser Gly Gly Val Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7214 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7214 Cys Ala Arg Gly Gly Glu Val Gly Asn Trp Phe Asp Pro Trp 1 5 10 <210> 7215 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7215 atgaccacag acacatccac gagcacagcc tacatggagc tgaggagcct gagatctgac 60 gacacggccg tgtattactg tgcgagaggg ggggaggtgg gtaactggtt cgacccctgg 120 ggccaggga 129 <210> 7216 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7216 Met Thr Thr Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser 1 5 10 15 Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Glu 20 25 30 Val Gly Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7217 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7217 atgaccacac acacatccac gagcacagcc tacatggagc tgaggagcct gagatctgac 60 gacacggccg tgtattactg tgcgagaggg ggggaggtgg gtaactggtt cgacccctgg 120 ggccaggga 129 <210> 7218 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7218 Met Thr Thr His Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser 1 5 10 15 Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Glu 20 25 30 Val Gly Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7219 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7219 Cys Ala Arg Ser Gly Asn Asp Tyr Gly Ser Gly Gly Val Leu Asp Tyr 1 5 10 15 Arg <210> 7220 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7220 gacaagtcca tcagcaccgc ctacctgcag tggagcagcc tgaaggcctc ggacaccgcc 60 atgtattact gtgcgagatc ggggaacgac tatggttcgg ggggagtgct tgactaccgg 120 ggccaggga 129 <210> 7221 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7221 Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala 1 5 10 15 Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Ser Gly Asn Asp Tyr Gly 20 25 30 Ser Gly Gly Val Leu Asp Tyr Arg Gly Gln Gly 35 40 <210> 7222 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7222 gacaagtcca tcaccaccgc ctacttgcag tggagcagcc tgaaggcctc ggacaccgcc 60 atgtattact gtgcgagatc ggggaacgac tatggttcgg ggggagtgct tgactaccgg 120 ggccaggga 129 <210> 7223 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7223 Asp Lys Ser Ile Thr Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala 1 5 10 15 Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Ser Gly Asn Asp Tyr Gly 20 25 30 Ser Gly Gly Val Leu Asp Tyr Arg Gly Gln Gly 35 40 <210> 7224 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7224 Cys Val Lys Val Gly Ser Gly Gly Tyr Asn Ala Asn Trp 1 5 10 <210> 7225 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7225 tacatctcaa gagatgattc agagaactca ctgtatctgc aaatgagcag cctgaagacc 60 gaggacacgg ccgtgtatta ttgtgttaaa gtagggtcgg gcggctacaa tgcgaactgg 120 ggccaggga 129 <210> 7226 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7226 Tyr Ile Ser Arg Asp Asp Ser Glu Asn Ser Leu Tyr Leu Gln Met Ser 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Val Lys Val Gly 20 25 30 Ser Gly Gly Tyr Asn Ala Asn Trp Gly Gln Gly 35 40 <210> 7227 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7227 accatctcaa gagatgattc agagaactca ctgtatctgc aaatgagcag cctgaagacc 60 gaggacacgg ccgtgtatta ttgtgttaaa gtagggtcgg gcggctacaa tgcgaactgg 120 ggccaggga 129 <210> 7228 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7228 Thr Ile Ser Arg Asp Asp Ser Glu Asn Ser Leu Tyr Leu Gln Met Ser 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Val Lys Val Gly 20 25 30 Ser Gly Gly Tyr Asn Ala Asn Trp Gly Gln Gly 35 40 <210> 7229 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7229 Cys Ala Arg Gly Gly Cys Ser Gly Gly Ser Cys Tyr Arg Asp Ala Phe 1 5 10 15 Asp Ile Trp <210> 7230 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7230 tccaagaact cgctgtatct tcaaatgaac agcctgagag ccgaggacac ggccgtgtat 60 tactgtgcga gaggtggttg tagtggtggt agctgctacc gagatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7231 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7231 Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Cys Ser Gly Gly Ser Cys 20 25 30 Tyr Arg Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7232 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7232 tccaagaaca cgctgtatct tcaaatgaac agcctgagag ccgaggacac ggccgtgtat 60 tactgtgcga gaggtggttg tagtggtggt agctgctacc gagatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7233 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7233 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Cys Ser Gly Gly Ser Cys 20 25 30 Tyr Arg Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7234 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7234 Cys Ala Arg Val Val Val Pro Ala Thr Pro Asp Ser Tyr Phe Asp Tyr 1 5 10 15 Trp <210> 7235 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7235 gacacgtcca tcagcacagc ctacatggag ctgagcaggc tgagatctga cgacacggcc 60 gtgtattact gtgcgagagt ggtagtacca gcgacgccgg actcgtactt tgactactgg 120 ggccaggga 129 <210> 7236 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7236 Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg Ser 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Val Val Pro Ala Thr 20 25 30 Pro Asp Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7237 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7237 gacacgtcca tcagcacagc ctacatggag ctaagcaggc tgagatctga cgacacggcc 60 gtgtattact gtgcgagagt ggtagtacca gcgacgccgg actcgtactt tgactactgg 120 ggccaggga 129 <210> 7238 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7238 Cys Ala Arg Asp Asp Gln Asp Ile Val Ala Thr Thr Gly Ile Pro Arg 1 5 10 15 Gly Met Asp Val Trp 20 <210> 7239 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7239 tgcacagcct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagacg accaagatat agtggctacg accgggatcc cacggggtat ggacgtctgg 120 ggccaaggg 129 <210> 7240 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7240 Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Asp Gln Asp Ile Val Ala Thr Thr Gly 20 25 30 Ile Pro Arg Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7241 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7241 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagacg accaagatat agtggctacg accgggatcc cacggggtat ggacgtctgg 120 ggccaaggg 129 <210> 7242 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7242 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Asp Gln Asp Ile Val Ala Thr Thr Gly 20 25 30 Ile Pro Arg Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7243 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7243 Cys Ala Arg Gly Gly Ala Gly Ala Val Thr Gln Asp Tyr Trp 1 5 10 <210> 7244 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7244 attaccgcgg acaaatccac gagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagaggg ggtgcggggg cggtgactca ggactactgg 120 ggccaggga 129 <210> 7245 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7245 Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Ala 20 25 30 Gly Ala Val Thr Gln Asp Tyr Trp Gly Gln Gly 35 40 <210> 7246 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7246 attaccgcgc acaaatccac gagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagaggg ggtgcggggg cggtgactca ggactactgg 120 ggccaggga 129 <210> 7247 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7247 Ile Thr Ala His Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Ala 20 25 30 Gly Ala Val Thr Gln Asp Tyr Trp Gly Gln Gly 35 40 <210> 7248 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7248 Cys Ala Arg Gly Gly Pro His Tyr Phe Asp Tyr Trp 1 5 10 <210> 7249 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7249 ttcaccatct ccagagaaaa tgccaagaac tccttgtatc ttcaaatgaa cagcctggga 60 gccggggaca cggctgtgta ttactgtgca agaggcggtc cccactactt tgactactgg 120 ggccaggga 129 <210> 7250 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7250 Phe Thr Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Gly Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly 20 25 30 Gly Pro His Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7251 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7251 ttcaccatct ccagagaaaa tgccaagaac tccttgtatc ttcaaatgaa cagcctgaga 60 gccggggaca cggctgtgta ttactgtgca agaggcggtc cccactactt tgactactgg 120 ggccaggga 129 <210> 7252 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7252 Phe Thr Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly 20 25 30 Gly Pro His Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7253 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7253 Cys Ala Arg Leu Arg Ser Gly Ser Leu Asp Tyr Trp 1 5 10 <210> 7254 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7254 gtcaccgtat tcgtagacac gcccaagaac cagttctccc tgtggctgag ctctgtgacc 60 gccgcagaca cggctgtgta ttactgtgcg agacttcgca gtgggagcct tgactactgg 120 ggccaggga 129 <210> 7255 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7255 Val Thr Val Phe Val Asp Thr Pro Lys Asn Gln Phe Ser Leu Trp Leu 1 5 10 15 Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu 20 25 30 Arg Ser Gly Ser Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7256 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7256 gtcaccgtat ccgtagacac gtccaagaac cagttctccc tgtggctgag ctctgtgacc 60 gccgcagaca cggctgtgta ttactgtgcg agacttcgca gtgggagcct tgactactgg 120 ggccaggga 129 <210> 7257 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7257 Val Thr Val Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Trp Leu 1 5 10 15 Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu 20 25 30 Arg Ser Gly Ser Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7258 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7258 Cys Ala His Arg Leu Gly Trp Phe Asp Pro Trp 1 5 10 <210> 7259 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7259 caggctcacc atcaccaagg acacctccaa aaccaggtgg tccttacaat gaccaacatg 60 gaccctgtgg acacagccac atattactgt gcacacaggt taggctggtt cgacccctgg 120 ggccaggga 129 <210> 7260 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7260 Gln Ala His His His Gln Gly His Leu Gln Asn Gln Val Val Leu Thr 1 5 10 15 Met Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His 20 25 30 Arg Leu Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7261 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7261 aggctcacca tcaccaagga cacctccaaa aaccaggtgg tccttacaat gaccaacatg 60 gaccctgtgg acacagccac atattactgt gcacacaggt taggctggtt cgacccctgg 120 ggccaggga 129 <210> 7262 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7262 Arg Leu Thr Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr 1 5 10 15 Met Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His 20 25 30 Arg Leu Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7263 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7263 Cys Ala Gln Ala Tyr Tyr Tyr Asp Ser Ser Gly Tyr Phe Gly Tyr Trp 1 5 10 15 <210> 7264 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7264 caaggacacc tccaaaacca ggtggtcctt acactgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca ggcgtattac tatgatagta gtggttactt tggctactgg 120 gaccaggga 129 <210> 7265 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7265 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Leu Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Gln Ala Tyr Tyr Tyr Asp 20 25 30 Ser Ser Gly Tyr Phe Gly Tyr Trp Asp Gln Gly 35 40 <210> 7266 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7266 aaggacacct ccaaaaacca ggtggtcctt acactgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca ggcgtattac tatgatagta gtggttactt tggctactgg 120 gaccaggga 129 <210> 7267 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7267 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Leu Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Gln Ala Tyr Tyr Tyr Asp 20 25 30 Ser Ser Gly Tyr Phe Gly Tyr Trp Asp Gln Gly 35 40 <210> 7268 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7268 Cys Ala Arg Val Cys Cys Gly Ile Thr Met Ile Val Val Val Ile Pro 1 5 10 15 Gly Ser Asn Tyr Tyr Phe Asp Tyr Trp 20 25 <210> 7269 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7269 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagtctgt 60 tgtggtatta ctatgatagt agtggttatt cctggctcca actactactt tgactactgg 120 ggccaggga 129 <210> 7270 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7270 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Val Cys Cys Gly Ile Thr Met Ile Val Val Val Ile Pro Gly 20 25 30 Ser Asn Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7271 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7271 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagtctgt 60 tgtggtatta ctatgatagt agtggttatt cctggctcca actactactt tgactactgg 120 ggccaggga 129 <210> 7272 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7272 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Val Cys Cys Gly Ile Thr Met Ile Val Val Val Ile Pro Gly 20 25 30 Ser Asn Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7273 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7273 Cys Ala Arg Met Arg Met Val Arg Gly Gly Asp Tyr Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 7274 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7274 tgcacagcct acttggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagaatga ggatggttcg gggaggtgat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7275 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7275 Cys Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Met Arg Met Val Arg Gly Gly Asp Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7276 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7276 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagaatga ggatggttcg gggaggtgat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7277 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7277 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Met Arg Met Val Arg Gly Gly Asp Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7278 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7278 Cys Ala His Arg Leu Arg Gly Ser Asn Val Leu Leu Trp Phe Gly Asp 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 7279 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7279 caggtggtcc ttacaatgac caacatggac cctgtggaca cagccgcata ttactgtgca 60 cacagactgc gaggaagcaa cgtgttacta tggttcgggg actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7280 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7280 Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala Ala 1 5 10 15 Tyr Tyr Cys Ala His Arg Leu Arg Gly Ser Asn Val Leu Leu Trp Phe 20 25 30 Gly Asp Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7281 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7281 caggtggtcc ttacaatgac caacatggac cctgtggaca cagccacata ttactgtgca 60 cacagactgc gaggaagcaa cgtattacta tggttcgggg actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7282 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7282 Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala Thr 1 5 10 15 Tyr Tyr Cys Ala His Arg Leu Arg Gly Ser Asn Val Leu Leu Trp Phe 20 25 30 Gly Asp Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7283 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7283 Cys Ala Arg Val Arg Ala Val Thr Gln Lys Asn Trp Phe Asp Pro Trp 1 5 10 15 <210> 7284 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7284 agggacacgt ccgtcagcac agcctacatg gagctgagca ggctgagatc tgacgacacg 60 gccgcgtatt actgtgcgag agtccgggcg gtgactcaga agaactggtt cgacccctgg 120 ggccaggga 129 <210> 7285 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7285 Arg Asp Thr Ser Val Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg 1 5 10 15 Ser Asp Asp Thr Ala Ala Tyr Tyr Cys Ala Arg Val Arg Ala Val Thr 20 25 30 Gln Lys Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7286 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7286 agggacacgt ccatcagcac agcctacatg gagctgagca ggctgagatc tgacgacacg 60 gccgtgtatt actgtgcgag agtccgggcg gtgactcaga agaactggtt cgacccctgg 120 ggccaggga 129 <210> 7287 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7287 Arg Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Arg Ala Val Thr 20 25 30 Gln Lys Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7288 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7288 Cys Ala Arg Glu Ser Ala Leu Gly Tyr Cys Ser Gly Gly Ser Cys Tyr 1 5 10 15 Ser Gly Thr Asp Phe Asp Tyr Trp 20 <210> 7289 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7289 tttctgaaaa tgaacggtct gagagccgag gacacggctg tgtattactg tgcaagagag 60 tcggccttag gatattgtag tggtggtagc tgctactccg gcacggactt tgactactgg 120 ggccaggga 129 <210> 7290 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7290 Phe Leu Lys Met Asn Gly Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Glu Ser Ala Leu Gly Tyr Cys Ser Gly Gly Ser Cys Tyr 20 25 30 Ser Gly Thr Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7291 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7291 tatctgcaaa tgaacggtct gagagccgag gacacggctg tgtattactg tgcaagagag 60 tcggccttag gatattgtag tggtggtagc tgctactccg gcacggactt tgactactgg 120 ggccaggga 129 <210> 7292 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7292 Tyr Leu Gln Met Asn Gly Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Glu Ser Ala Leu Gly Tyr Cys Ser Gly Gly Ser Cys Tyr 20 25 30 Ser Gly Thr Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7293 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7293 Cys Ala Arg Val Pro Val Gly Asp Tyr Tyr Gly Met Asp Val Trp 1 5 10 15 <210> 7294 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7294 tccagagaaa atgccaagaa ctccttgtat cttcaaatga acagcctgag agccggggac 60 acggctgtgt attactgtgc aagagtcccc gtcggtgact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7295 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7295 Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Pro Val Gly 20 25 30 Asp Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7296 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7296 tacagagaaa atgccaagaa ctccttgtat cttcaaatga acagcctgag agccggtgac 60 acggctgtgt attactgtgc aagagtcccc gtcggtgact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7297 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7297 Tyr Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Pro Val Gly 20 25 30 Asp Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7298 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7298 Cys Ala Arg Gly Thr Asp Tyr Tyr Gly Ser Gly Ser Tyr Tyr Asn Ser 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 7299 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7299 ttggagctga gcagcctgag atctgaggac acggccgtgt attactgtgc gagagggacg 60 gattactatg gttcagggag ttattataac agttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7300 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7300 Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Thr Asp Tyr Tyr Gly Ser Gly Ser Tyr Tyr Asn Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7301 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7301 atggagctga gcagcctgag atctgaggac acggccgtgt attactgtgc gagagggacg 60 gattactatg gttcagggag ttattataac agttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7302 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7302 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Thr Asp Tyr Tyr Gly Ser Gly Ser Tyr Tyr Asn Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7303 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7303 Cys Ala Arg Pro Leu Val Asp Asp Ala Phe Asp Ile Trp 1 5 10 <210> 7304 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7304 accatctcag ccgacaagtc catcagcacc gcctacctgc agtggagcag cctgaaggcc 60 tcggacaccg ccatgtatta ctgtgcgaga ccccttgtcg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7305 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7305 Thr Ile Ser Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser 1 5 10 15 Ser Leu Lys Ala Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Pro Leu 20 25 30 Val Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7306 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7306 accatctcag ccgacaagtc catcagcacc gcctacctgc agtggagcag cctgaaggcc 60 tcggacaccg ccacgtacta ctgtgcgaga ccccttgtcg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7307 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7307 Thr Ile Ser Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser 1 5 10 15 Ser Leu Lys Ala Ser Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Pro Leu 20 25 30 Val Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7308 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7308 Cys Ala Lys Asp Phe Gln Trp Leu Arg Ile Gly Gly Gly Phe Asp Tyr 1 5 10 15 Trp <210> 7309 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7309 gacaattcca ggaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggct 60 atgtattact gtgcgaaaga ttttcagtgg ttacgaattg gggggggttt tgactactgg 120 ggccaggga 129 <210> 7310 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7310 Asp Asn Ser Arg Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Met Tyr Tyr Cys Ala Lys Asp Phe Gln Trp Leu Arg 20 25 30 Ile Gly Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7311 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7311 gacaattcca gcaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggct 60 atgtattact gtgcgaaaga ttttcagtgg ttacgaattg gggggggttt tgactactgg 120 ggccaggga 129 <210> 7312 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7312 Asp Asn Ser Ser Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Met Tyr Tyr Cys Ala Lys Asp Phe Gln Trp Leu Arg 20 25 30 Ile Gly Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7313 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7313 Cys Ala Arg Gly Arg Gly Thr His Trp Phe Asp Pro Trp 1 5 10 <210> 7314 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7314 accatgacca ggaacacctc cataagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ggccggggta cacactggtt cgacccctgg 120 ggccaggga 129 <210> 7315 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7315 Thr Met Thr Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg 20 25 30 Gly Thr His Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7316 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7316 accatgacca gcaacacctc cataagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ggccggggta cacactggtt cgacccctgg 120 ggccaggga 129 <210> 7317 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7317 Thr Met Thr Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg 20 25 30 Gly Thr His Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7318 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7318 Cys Ala Arg Tyr Pro Arg Ala Leu Gly Gly Leu Gly Arg Ala Leu Ala 1 5 10 15 Pro Ser Asp Tyr Trp 20 <210> 7319 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7319 tgcacagcct acatggagct gaggagcctg agatctgacg acacggccgt atattactgt 60 gcgagatacc ctcgggccct gggaggtttg ggtcgggcac tggccccctc tgactactgg 120 ggccaggga 129 <210> 7320 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7320 Cys Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Tyr Pro Arg Ala Leu Gly Gly Leu Gly Arg 20 25 30 Ala Leu Ala Pro Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 7321 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7321 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt atattactgt 60 gcgagatacc ctcgggccct gggaggtttg ggtcgggcac tggccccctc tgactactgg 120 ggccaggga 129 <210> 7322 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7322 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Tyr Pro Arg Ala Leu Gly Gly Leu Gly Arg 20 25 30 Ala Leu Ala Pro Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 7323 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7323 Cys Ala Arg Asp Gln Arg Ile Ala Ala Ala Asp Tyr Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 7324 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7324 tgcacagtct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatc agaggatagc agcagctgat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7325 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7325 Cys Thr Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Gln Arg Ile Ala Ala Ala Asp Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7326 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7326 agcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatc agaggatagc agcagctgat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7327 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7327 Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Gln Arg Ile Ala Ala Ala Asp Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7328 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7328 Cys Ala Lys Phe Asp Tyr Trp Ile Asp Tyr Tyr Gly Ser Gly Ser Tyr 1 5 10 15 Gly Thr Gly Gly Tyr Phe Asp Tyr Trp 20 25 <210> 7329 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7329 ctgcaaatga acagcctgag agccgaggac acggccgtat attactgtgc gaagttcgac 60 tactggatag attactatgg ttcggggagt tatggaacgg gtggctactt tgactactgg 120 ggccaggga 129 <210> 7330 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7330 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Lys Phe Asp Tyr Trp Ile Asp Tyr Tyr Gly Ser Gly Ser Tyr Gly 20 25 30 Thr Gly Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7331 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7331 ctgaaaatga actgcctgag agccgaggac acggccgtat attactgtgc gaagttcgac 60 tactggatag attactatgg ttcggggagt tatggaacgg gtggctactt tgactactgg 120 ggccaggga 129 <210> 7332 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7332 Leu Lys Met Asn Cys Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Lys Phe Asp Tyr Trp Ile Asp Tyr Tyr Gly Ser Gly Ser Tyr Gly 20 25 30 Thr Gly Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7333 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7333 Cys Val Lys Gly Thr Ile Pro Ile Phe Gly Val Ile Arg Ser Ala Phe 1 5 10 15 Asp Tyr Trp <210> 7334 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7334 gccaagaact ccctgtatgt gcaattgaac agtctgagat ctgaggacac ggccttgtat 60 tattgtgtaa aagggactat tccgatcttt ggagtgatta ggagcgcttt tgactactgg 120 ggccagggg 129 <210> 7335 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7335 Ala Lys Asn Ser Leu Tyr Val Gln Leu Asn Ser Leu Arg Ser Glu Asp 1 5 10 15 Thr Ala Leu Tyr Tyr Cys Val Lys Gly Thr Ile Pro Ile Phe Gly Val 20 25 30 Ile Arg Ser Ala Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7336 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7336 cgccaagaac tcctgtatgt gcaattgaac agtctgagat ctgaggacac ggccttgtat 60 tattgtgtaa aagggactat tccgatcttt ggagtgatta ggagcgcttt tgactactgg 120 ggccagggg 129 <210> 7337 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7337 Arg Gln Glu Leu Leu Tyr Val Gln Leu Asn Ser Leu Arg Ser Glu Asp 1 5 10 15 Thr Ala Leu Tyr Tyr Cys Val Lys Gly Thr Ile Pro Ile Phe Gly Val 20 25 30 Ile Arg Ser Ala Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7338 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7338 Cys Ala Arg Ser Gly Tyr Ser Ser Gly Trp Tyr Gly Asp Tyr Trp 1 5 10 15 <210> 7339 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7339 tacagggaca tgtccacgag gacagtctac atggagctga gcagcctgag atctgaggac 60 acggccgtgt attactgtgc gagatccgga tatagcagtg gctggtacgg agactactgg 120 ggccaggga 129 <210> 7340 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7340 Tyr Arg Asp Met Ser Thr Arg Thr Val Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ser Gly Tyr Ser 20 25 30 Ser Gly Trp Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 7341 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7341 accagggaca tgtccacgag gacagtctac atggagctga gcagcctgag atctgaggac 60 acggccgtgt attactgtgc gagatccgga tatagcagtg gctggtacgg agactactgg 120 ggccaggga 129 <210> 7342 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7342 Thr Arg Asp Met Ser Thr Arg Thr Val Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ser Gly Tyr Ser 20 25 30 Ser Gly Trp Tyr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 7343 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7343 Cys Ala His Arg Arg Pro Trp Asp Tyr Phe Asp Tyr Trp 1 5 10 <210> 7344 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7344 caccatcacc aaggacacct ccaaaaccag gtggtcctta caatgaccaa catggaccct 60 gtggacacag ccacatatta ctgtgcacac agacgtccct gggactactt tgactactgg 120 ggccaggga 129 <210> 7345 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7345 His His His Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg 20 25 30 Pro Trp Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7346 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7346 accatcacca aggacacctc caaaaaccag gtggtcctta caatgaccaa catggaccct 60 gtggacacag ccacatatta ctgtgcacac agacgtccct gggactactt tgactactgg 120 ggccaggga 129 <210> 7347 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7347 Thr Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Arg 20 25 30 Pro Trp Asp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7348 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7348 Cys Ala Arg Gly Gly Tyr Tyr Gly Ser Gly Ser Arg Gly Asp Trp Phe 1 5 10 15 Asp Pro Trp <210> 7349 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7349 tccaagaacc tgttctccct gaagctgagc tctgtgaccg ccgcggacac ggccgtgtat 60 tactgtgcga gaggcggtta ctatggttca gggagtagag gggactggtt cgacccctgg 120 ggccaggga 129 <210> 7350 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7350 Ser Lys Asn Leu Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Tyr Tyr Gly Ser Gly Ser 20 25 30 Arg Gly Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7351 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7351 tccaagaacc agttctccct gaagctgagc tctgtgaccg ccgcggacac ggccgtgtat 60 tactgtgcga gaggcggtta ctatggttca gggagtagag gggactggtt cgacccctgg 120 ggccaggga 129 <210> 7352 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7352 Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Tyr Tyr Gly Ser Gly Ser 20 25 30 Arg Gly Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7353 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7353 Cys Ala Arg Arg Gly Val Arg Pro Phe Ser Asp Gly Met Asp Val Trp 1 5 10 15 <210> 7354 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7354 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcacg ccgcggtgta cgtcccttct ctgacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7355 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7355 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Arg Gly Val Arg Pro 20 25 30 Phe Ser Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7356 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7356 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcacg ccgcggtgta cgtcccttct ctgacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7357 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7357 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Arg Gly Val Arg Pro 20 25 30 Phe Ser Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7358 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7358 Cys Ala Arg Asp Gly Leu Ile Val Gly Ala Thr Thr Gly Pro Ser Trp 1 5 10 15 Tyr Phe Asp Leu Trp 20 <210> 7359 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7359 tgcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatg gtcttatagt gggagctacc acgggcccct cgtggtactt cgatctctgg 120 ggccgtggc 129 <210> 7360 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7360 Cys Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Gly Leu Ile Val Gly Ala Thr Thr Gly 20 25 30 Pro Ser Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 7361 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7361 agcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatg gtcttatagt gggagctacc acgggcccct cgtggtactt cgatctctgg 120 ggccgtggc 129 <210> 7362 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7362 Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Gly Leu Ile Val Gly Ala Thr Thr Gly 20 25 30 Pro Ser Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 7363 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7363 Cys Ala Arg Asp Arg Asp Tyr Ile Thr Ala Thr Tyr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 7364 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7364 acgagcacgg cctacatgga gctgaggagc ctgagatctg acgacacggc cgtgtattac 60 tgtgcgagag atcgggacta cataaccgca acctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7365 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7365 Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Asp Arg Asp Tyr Ile Thr Ala Thr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7366 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7366 acgagcacag cctacatgga gctgaggagc ctgagatctg acgacacggc cgtgtattac 60 tgtgcgagag atcgggacta cataaccgca acctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7367 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7367 Cys Ala Lys Asp Ser His Asp Ile Leu Thr Gly Pro Asp Tyr Trp 1 5 10 15 <210> 7368 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7368 tccagagaca acgccaagaa ctccctgtat ctgcaaatga acagtctgag agctgaggac 60 acggccttgt attactgtgc aaaagatagt cacgatattt tgactggtcc tgactactgg 120 ggccaggga 129 <210> 7369 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7369 Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Ser His Asp 20 25 30 Ile Leu Thr Gly Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 7370 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7370 tacagagaca acgccaagaa ctccctgtat ctgcaaatga acagtctgag agctgaggac 60 actgccttgt attactgtgc aaaagatagt cacgatattt tgactggtcc tgactactgg 120 ggccaggga 129 <210> 7371 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7371 Tyr Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Ser His Asp 20 25 30 Ile Leu Thr Gly Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 7372 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7372 Cys Ala Arg Ala Glu Tyr Tyr Tyr Asp Ser Ser Gly Tyr Phe Asp Tyr 1 5 10 15 Trp <210> 7373 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7373 ggcaattcca agaacacgct gtatcttcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgcgagagc agaatattac tatgatagta gtggttattt tgactactgg 120 ggccaggga 129 <210> 7374 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7374 Gly Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Glu Tyr Tyr Tyr Asp 20 25 30 Ser Ser Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7375 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7375 gacaattcca agaacacgct gtatcttcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgcgagagc agaatattac tatgatagta gtggttattt tgactactgg 120 ggccaggga 129 <210> 7376 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7376 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Glu Tyr Tyr Tyr Asp 20 25 30 Ser Ser Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7377 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7377 Cys Ala Arg Asp Leu Gly Ala Ala Ala Asp Leu Ile Asp Tyr Trp 1 5 10 15 <210> 7378 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7378 caaccagaca catccaagaa ccagttctcc ctgcagctga actctgtgac tcccgaggac 60 acggctgtgt attactgtgc aagagatttg ggggcagcag ctgatctcat tgactactgg 120 ggccaggga 129 <210> 7379 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7379 Gln Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser Val 1 5 10 15 Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu Gly Ala 20 25 30 Ala Ala Asp Leu Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 7380 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7380 aacccagaca catccaagaa ccagttctcc ctgcagctga actctgtgac tcccgaggac 60 acggctgtgt attactgtgc aagagatttg ggggcagcag ctgatctcat tgactactgg 120 ggccaggga 129 <210> 7381 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7381 Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser Val 1 5 10 15 Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu Gly Ala 20 25 30 Ala Ala Asp Leu Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 7382 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7382 Cys Ala Arg Asp Ser Phe Gly Ile Ala Val Ala Gly Arg Glu Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 7383 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7383 tcagcctaca tggagctgag cagcctgata tctgaggaca cggccgtgta ttactgtgcg 60 agagacagct tcggtatagc agtggccggt agggagtact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7384 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7384 Ser Ala Tyr Met Glu Leu Ser Ser Leu Ile Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Ser Phe Gly Ile Ala Val Ala Gly Arg Glu 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7385 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7385 acagcctaca tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agagacagct tcggtatagc agtggccggt agggagtact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7386 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7386 Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Ser Phe Gly Ile Ala Val Ala Gly Arg Glu 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7387 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7387 Cys Ala Lys Gly Pro Ser Gly Tyr Ser Ser Ser Trp Phe Asp Tyr Trp 1 5 10 15 <210> 7388 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7388 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agggccttcc gggtatagca gcagctggtt tgactactgg 120 ggccaggga 129 <210> 7389 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7389 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Pro Ser Gly Tyr 20 25 30 Ser Ser Ser Trp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7390 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7390 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agggccttcc gggtacagca gcagctggtt cgactactgg 120 ggccaggga 129 <210> 7391 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7391 Cys Ala Arg Gln Ala Pro Gly Gly Tyr Gly Tyr Gly Tyr Trp 1 5 10 <210> 7392 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7392 ctctccagag acaattccaa gaacacgttg tatcttcaaa tggacagcct gagagccgag 60 gacacggccg tttattactg tgcgagacag gccccgggcg gctatggtta cgggtactgg 120 ggccaggga 129 <210> 7393 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7393 Leu Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asp Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gln Ala Pro 20 25 30 Gly Gly Tyr Gly Tyr Gly Tyr Trp Gly Gln Gly 35 40 <210> 7394 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7394 ctctccagag acaattccaa gaacacgttg tatcttcaaa tggacagcct gagagccgag 60 gacacggccg gttattactg tgcgagacag gccccgggcg gctatggtta cgggtactgg 120 ggccaggga 129 <210> 7395 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7395 Leu Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asp Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Gly Tyr Tyr Cys Ala Arg Gln Ala Pro 20 25 30 Gly Gly Tyr Gly Tyr Gly Tyr Trp Gly Gln Gly 35 40 <210> 7396 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7396 Cys Ala Lys Asp Leu Gly Ser Ser Trp Pro Ser Arg Tyr Tyr Tyr Tyr 1 5 10 15 Tyr Tyr Gly Met Asp Val Trp 20 <210> 7397 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7397 ctgtatctgc aaatgaacag cctgagagcc gaggacacgg ccgtatatta ctgtgcgaaa 60 gatctaggca gcagctggcc ctcccgatat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7398 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7398 Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Lys Asp Leu Gly Ser Ser Trp Pro Ser Arg Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7399 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7399 ctgtatatgc aaatcaacag cctgagagcc gaggacacgg ccgtatatta ctgtgcgaaa 60 gatctaggca gcagctggcc ctcccgatat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7400 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7400 Leu Tyr Met Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Lys Asp Leu Gly Ser Ser Trp Pro Ser Arg Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7401 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7401 Cys Ala His Thr Ala Ser Ser Gly Trp Arg Gly Glu Tyr Phe Gln His 1 5 10 15 Trp <210> 7402 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7402 gacacctcca aaaacctggt ggtcattaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacac cgccagcagt ggctggcggg gggaatactt ccagcactgg 120 ggccagggc 129 <210> 7403 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7403 Asp Thr Ser Lys Asn Leu Val Val Ile Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Thr Ala Ser Ser Gly Trp 20 25 30 Arg Gly Glu Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 7404 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7404 gacacctcca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacac cgccagcagt ggctggcggg gggaatactt ccagcactgg 120 ggccagggc 129 <210> 7405 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7405 Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Thr Ala Ser Ser Gly Trp 20 25 30 Arg Gly Glu Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 7406 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7406 Cys Ala Arg Asp Gln Ala Gly Ala Phe Asp Ile Trp 1 5 10 <210> 7407 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7407 ataaccatca acccagacac atccaagaac cagttctccc tgcagctgaa ctctgtgact 60 cccgaggaca cggctgtgta ttactgtgca agagaccagg ctggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 7408 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7408 Ile Thr Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu 1 5 10 15 Asn Ser Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Gln Ala Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7409 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7409 ataaccatca acccagacac atccaagaac cagttctccc tgcagctgaa ctccgtgact 60 cccgaggaca cggctgtgta ttactgtgca agagaccagg ctggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 7410 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7410 Cys Ala Ser Leu Asn Ser Ser Gly Thr Ser Arg Val Phe Pro Val Arg 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 7411 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7411 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagcctgaat 60 agcagtggca catcacgtgt atttcccgtt cgctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7412 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7412 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Ser Leu Asn Ser Ser Gly Thr Ser Arg Val Phe Pro Val Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7413 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7413 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagcctgaat 60 agcagtggca catcacgtgt atttcccgtt cgctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7414 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7414 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Ser Leu Asn Ser Ser Gly Thr Ser Arg Val Phe Pro Val Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7415 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7415 Cys Ala Arg Glu Gly Val Gly Ala Phe Arg Asp Trp 1 5 10 <210> 7416 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7416 ttcaccatct acagagacaa ttccaagaac acgttgtatc ttcaaatgaa cagcctgaga 60 gccgacgaca cggccgtgta ttactgtgcg agagaagggg tcggggcctt cagggattgg 120 ggccaggga 129 <210> 7417 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7417 Phe Thr Ile Tyr Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu 20 25 30 Gly Val Gly Ala Phe Arg Asp Trp Gly Gln Gly 35 40 <210> 7418 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7418 ttcaccatct acagacacaa ttccaagaac acgttgtatc ttcaaatcaa cagcctgaga 60 gccgacgaca cggccgtgta ttactgtgcg agagaagggg tcggggcctt cagggattgg 120 ggccaggga 129 <210> 7419 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7419 Phe Thr Ile Tyr Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile 1 5 10 15 Asn Ser Leu Arg Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu 20 25 30 Gly Val Gly Ala Phe Arg Asp Trp Gly Gln Gly 35 40 <210> 7420 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7420 Cys Ala Lys Asp Leu Thr Ile Phe Gly Val Val Pro Phe Asp Tyr Trp 1 5 10 15 <210> 7421 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7421 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagggc cgaggacacg 60 gccgtatatt actgtgcgaa agatctaacg atttttggag tggtgccctt tgactactgg 120 ggccaggga 129 <210> 7422 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7422 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Thr Ile Phe 20 25 30 Gly Val Val Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7423 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7423 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatctaacg atttttggag tggtgccctt tgactactgg 120 ggccaggga 129 <210> 7424 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7424 Cys Ala Lys Gly Arg Gly Gly Leu Asp Val Trp 1 5 10 <210> 7425 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7425 cggttcacca tatccagata taattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattattgt gccaagggcc ggggcggtct ggacgtctgg 120 ggccaaggg 129 <210> 7426 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7426 Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Gly Arg Gly Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 7427 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7427 cggttcacca tatccagaga taattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattattgt gccaagggcc ggggcggtct ggacgtctgg 120 ggccaaggg 129 <210> 7428 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7428 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Gly Arg Gly Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 7429 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7429 Cys Thr Arg Glu Met Gly Gly Trp Arg Glu His Asp Tyr Trp 1 5 10 <210> 7430 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7430 atctccagag acaattccaa gaacacgctg tatcttcaaa tgggcagcct gcgagctgag 60 gacgtggctg tgtattactg tacgagggag atgggaggtt ggcgcgagca cgactactgg 120 ggccaggga 129 <210> 7431 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7431 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Gly Ser 1 5 10 15 Leu Arg Ala Glu Asp Val Ala Val Tyr Tyr Cys Thr Arg Glu Met Gly 20 25 30 Gly Trp Arg Glu His Asp Tyr Trp Gly Gln Gly 35 40 <210> 7432 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7432 atctccagag acaattccaa gaacacgctg tatcttcaaa tgggcagcct gcgagctgag 60 gacatggctg tgtattactg tacgagggag atgggaggtt ggcgcgagca cgactactgg 120 ggccaggga 129 <210> 7433 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7433 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Gly Ser 1 5 10 15 Leu Arg Ala Glu Asp Met Ala Val Tyr Tyr Cys Thr Arg Glu Met Gly 20 25 30 Gly Trp Arg Glu His Asp Tyr Trp Gly Gln Gly 35 40 <210> 7434 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7434 Cys Ala Arg Asp Phe Arg Gly Val Ala Pro Tyr Tyr Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 7435 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7435 tgcacagcct acttggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagatt ttcggggagt tgccccatat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7436 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7436 Cys Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Phe Arg Gly Val Ala Pro Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7437 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7437 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagatt ttcggggagt tgccccatat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7438 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7438 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Phe Arg Gly Val Ala Pro Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7439 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7439 Cys Ala His Arg Thr Lys Gly Tyr Gly Asp Tyr Ser Tyr Tyr Phe Asp 1 5 10 15 Tyr Trp <210> 7440 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7440 acctccaaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacaggac caaggggtac ggtgactact cctactactt tgactactgg 120 ggccaggga 129 <210> 7441 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7441 Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Thr Lys Gly Tyr Gly Asp 20 25 30 Tyr Ser Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7442 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7442 cacctccaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacaggac caaggggtac ggtgactact cctactactt tgactactgg 120 ggccaggga 129 <210> 7443 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7443 His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Thr Lys Gly Tyr Gly Asp 20 25 30 Tyr Ser Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7444 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7444 Cys Ala Lys Asp Trp Leu Leu Val His Asn Trp Phe Asp Pro Trp 1 5 10 15 <210> 7445 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7445 tccagagaca attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaagattgg ctgctggttc acaactggtt cgacccctgg 120 ggccaggga 129 <210> 7446 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7446 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Trp Leu Leu 20 25 30 Val His Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7447 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7447 tacagagaca attccaagaa cacgctgtat ctgaaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaagattgg ctgctggttc acaactggtt cgacccctgg 120 ggccaggga 129 <210> 7448 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7448 Tyr Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Lys Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Trp Leu Leu 20 25 30 Val His Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7449 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7449 Cys Thr Thr Asp Ser Ala Pro Asn Thr Phe Ser Gly Arg Trp Tyr Gly 1 5 10 15 Ala Phe Asp Ile Trp 20 <210> 7450 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7450 aacacactat atctgcaaat gaacagcctg aaaaccgaag acacagccgt atattactgt 60 accacagaca gcgcccctaa cacttttagc ggcaggtggt atggtgcttt tgatatatgg 120 ggccaaggg 129 <210> 7451 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7451 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Thr Thr Asp Ser Ala Pro Asn Thr Phe Ser Gly Arg 20 25 30 Trp Tyr Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7452 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7452 aaacacacta tatctgcaaa tgaacagcct gaaaccgaag acacagccgt atattactgt 60 accacagaca gcgcccctaa cacttttagc ggcaggtggt atggtgcttt tgatatatgg 120 ggccaaggg 129 <210> 7453 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7453 Lys His Thr Ile Ser Ala Asn Glu Gln Pro Glu Thr Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Thr Thr Asp Ser Ala Pro Asn Thr Phe Ser Gly Arg 20 25 30 Trp Tyr Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7454 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7454 Cys Ala Arg Glu Ala Gly Val Ser Arg Arg Asp Leu Asp Tyr Trp 1 5 10 15 <210> 7455 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7455 tccagagaca acgccaagaa cacgctgtat ctgcaaatga atagtctgag agccgaggac 60 acggctgtgt tttactgtgc aagagaggct ggtgtgagca gaagagactt agactactgg 120 ggccaggga 129 <210> 7456 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7456 Ser Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Phe Tyr Cys Ala Arg Glu Ala Gly Val 20 25 30 Ser Arg Arg Asp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7457 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7457 tccagagaca accccaacaa cacgctgtat ctgcaaatga atagtctgag agccgaggac 60 acggctgtgt tttactgtgc aagagaggct ggtgtgagca gaagagactt agactactgg 120 ggccaggga 129 <210> 7458 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7458 Ser Arg Asp Asn Pro Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Phe Tyr Cys Ala Arg Glu Ala Gly Val 20 25 30 Ser Arg Arg Asp Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7459 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7459 Cys Ala Arg Met Gly Ala Ser Tyr Gly Ser Ser Leu Asp Pro Trp 1 5 10 15 <210> 7460 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7460 ctccaaggac acctccaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acggatgggg gcctcttatg gttcgtccct cgacccctgg 120 ggccaggga 129 <210> 7461 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7461 Leu Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Met Gly Ala Ser 20 25 30 Tyr Gly Ser Ser Leu Asp Pro Trp Gly Gln Gly 35 40 <210> 7462 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7462 tccaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acggatgggg gcctcttatg gttcgtccct cgacccctgg 120 ggccaggga 129 <210> 7463 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7463 Ser Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Met Gly Ala Ser 20 25 30 Tyr Gly Ser Ser Leu Asp Pro Trp Gly Gln Gly 35 40 <210> 7464 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7464 Cys Ala Lys Asp His Tyr Tyr Ser Ser Gly Ser Ser Gly Tyr Phe Gln 1 5 10 15 His Trp <210> 7465 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7465 aacgccaaga attccctgta tttgcaaatg aacagtctga gagttgagga cactgccttg 60 tattactgtg caaaagacca ttactattct tcagggagct ctgggtactt ccagcactgg 120 ggccagggc 129 <210> 7466 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7466 Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Val Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp His Tyr Tyr Ser Ser Gly 20 25 30 Ser Ser Gly Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 7467 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7467 aacgccaaga attccctgta tctgcaaatg aacagtctga gagttgagga cactgccttg 60 tattactgtg caaaagacca ttactattct tcagggagct ctgggtactt ccagcactgg 120 ggccagggc 129 <210> 7468 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7468 Cys Ala Leu Asn Tyr Gly Ser Gly Ser Tyr Gln Gly Asp Pro Gly Tyr 1 5 10 15 Tyr Tyr His Gly Met Asp Val Trp 20 <210> 7469 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7469 tatctgcaaa tgaacagcct gagagacgaa gacacggctg tgtattactg tgcgttgaac 60 tatggttcgg ggagttatca gggtgaccca gggtactact accacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7470 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7470 Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Leu Asn Tyr Gly Ser Gly Ser Tyr Gln Gly Asp Pro Gly Tyr 20 25 30 Tyr Tyr His Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7471 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7471 tatctgaaaa tcaacagcct gagagacgaa gacacggctg tgtattactg tgcgttgaac 60 tatggttcgg ggagttatca gggtgaccca gggtactact accacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7472 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7472 Tyr Leu Lys Ile Asn Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Leu Asn Tyr Gly Ser Gly Ser Tyr Gln Gly Asp Pro Gly Tyr 20 25 30 Tyr Tyr His Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7473 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7473 Cys Ala His Gly Leu Ser Ser Gly Trp Tyr Arg Thr Asn Trp Phe Asp 1 5 10 15 Pro Trp <210> 7474 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7474 acctccaaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacggact aagcagtggc tggtacagga ccaactggtt cgacccctgg 120 ggccaggga 129 <210> 7475 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7475 Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Leu Ser Ser Gly Trp Tyr 20 25 30 Arg Thr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7476 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7476 cacctccaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacggact aagcagtggc tggtacagga ccaactggtt cgacccctgg 120 ggccaggga 129 <210> 7477 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7477 His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Leu Ser Ser Gly Trp Tyr 20 25 30 Arg Thr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7478 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7478 Cys Ala Arg Gly Glu Val Gly His Asp Glu Phe Asp Ile Trp 1 5 10 <210> 7479 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7479 attttagtag acacgtccaa gaatcagctg tccctgacga tgaactctgt gagtgccgct 60 gacacggccc tttattactg tgcgagaggc gaagtggggc atgatgagtt cgatatctgg 120 ggccaaggg 129 <210> 7480 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7480 Ile Leu Val Asp Thr Ser Lys Asn Gln Leu Ser Leu Thr Met Asn Ser 1 5 10 15 Val Ser Ala Ala Asp Thr Ala Leu Tyr Tyr Cys Ala Arg Gly Glu Val 20 25 30 Gly His Asp Glu Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7481 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7481 Cys Thr His Asn Val Gly Gly Trp Asp Gly Pro Tyr Ser Asp Cys Trp 1 5 10 15 <210> 7482 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7482 aaggacactt ccgaaaaccg ggtgatcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt tctgtacaca caatgttgga ggctgggatg ggccctactc tgactgctgg 120 ggccaggga 129 <210> 7483 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7483 Lys Asp Thr Ser Glu Asn Arg Val Ile Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Phe Cys Thr His Asn Val Gly Gly Trp 20 25 30 Asp Gly Pro Tyr Ser Asp Cys Trp Gly Gln Gly 35 40 <210> 7484 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7484 aaggacacct ccaaaaaccg ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt tctgtacaca caatgttgga ggctgggatg ggccctactc tgactgctgg 120 ggccaggga 129 <210> 7485 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7485 Lys Asp Thr Ser Lys Asn Arg Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Phe Cys Thr His Asn Val Gly Gly Trp 20 25 30 Asp Gly Pro Tyr Ser Asp Cys Trp Gly Gln Gly 35 40 <210> 7486 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7486 Cys Ala Arg Asp Ser Met Val Arg Gly Val Ala Glu Gly Asp Ala Phe 1 5 10 15 Asp Ile Trp <210> 7487 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7487 gccaagaact cgctctttct gcaaatgaac agtctgagag ccgaggacac ggctgtgtat 60 tactgtgcaa gagacagtat ggttcgggga gttgccgagg gggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7488 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7488 Ala Lys Asn Ser Leu Phe Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ser Met Val Arg Gly Val Ala 20 25 30 Glu Gly Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7489 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7489 gccaagaaca cgctctttct gcaaatgaac agtctgagag ccgaggacac ggctgtgtat 60 tactgtgcaa gagacagtat ggttcgggga gttgccgagg gggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7490 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7490 Ala Lys Asn Thr Leu Phe Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ser Met Val Arg Gly Val Ala 20 25 30 Glu Gly Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7491 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7491 Cys Ala Arg Val His His Leu Gly Arg Gly Phe Ala Tyr Trp 1 5 10 <210> 7492 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7492 atcttcccag acacatccaa gaaccagttc tccctgcagc tgacctctgt gactcccgag 60 gacacggctg tgtattactg tgcaagagtc catcacctcg gccgggggtt tgcctactgg 120 ggccaggga 129 <210> 7493 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7493 Ile Phe Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Thr Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val His His 20 25 30 Leu Gly Arg Gly Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 7494 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7494 atcaacccag acacatccaa gaaccagttc tccctgcagc tgacctctgt gactcccgag 60 gacacggctg tgtattactg tgcaagagtc catcacctcg gccgggggtt tgcctactgg 120 ggccaggga 129 <210> 7495 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7495 Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Thr Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val His His 20 25 30 Leu Gly Arg Gly Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 7496 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7496 Cys Ala Arg Ala Asp Glu Asp Ile Ala Pro Pro Asp Tyr Trp 1 5 10 <210> 7497 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7497 atgaccacag acacattcac gagcacagcc tacatggagc tgaggagcct gagatctgac 60 gacacggccg tctattattg tgcgagagct gatgaggata tagccccccc cgactactgg 120 ggccaggga 129 <210> 7498 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7498 Met Thr Thr Asp Thr Phe Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser 1 5 10 15 Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Asp Glu 20 25 30 Asp Ile Ala Pro Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 7499 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7499 atgaccacac acacattcac gaccacagcc tacatggagc tgaggagcct gagatctgac 60 gacacggccg tctattattg tgcgagagct gatgaggata tagccccccc cgactactgg 120 ggccaggga 129 <210> 7500 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7500 Met Thr Thr His Thr Phe Thr Thr Thr Ala Tyr Met Glu Leu Arg Ser 1 5 10 15 Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Asp Glu 20 25 30 Asp Ile Ala Pro Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 7501 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7501 Cys Ala Arg Ala Leu Glu Pro Thr Val Gly Asp Val Trp 1 5 10 <210> 7502 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7502 acgattaccg cggacaaatc cacgagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga gctctagagc cgaccgtggg ggacgtctgg 120 ggccaaggg 129 <210> 7503 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7503 Thr Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Leu 20 25 30 Glu Pro Thr Val Gly Asp Val Trp Gly Gln Gly 35 40 <210> 7504 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7504 acgattaccg cgcacaaatc cacgagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga gctctagagc cgaccgtggg ggacgtctgg 120 ggccaaggg 129 <210> 7505 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7505 Thr Ile Thr Ala His Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Leu 20 25 30 Glu Pro Thr Val Gly Asp Val Trp Gly Gln Gly 35 40 <210> 7506 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7506 Cys Ala His Arg Ser Leu Tyr Tyr Tyr Gly Ser Gly Ser Trp Asp Tyr 1 5 10 15 Trp <210> 7507 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7507 gacacctcca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacaccg atctctgtat tactatggtt cagggagttg ggactactgg 120 ggccaggga 129 <210> 7508 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7508 Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Ser Leu Tyr Tyr Tyr 20 25 30 Gly Ser Gly Ser Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 7509 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7509 ggacacctcc aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacaccg atctctgtat tactatggtt cagggagttg ggactactgg 120 ggccaggga 129 <210> 7510 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7510 Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Ser Leu Tyr Tyr Tyr 20 25 30 Gly Ser Gly Ser Trp Asp Tyr Trp Gly Gln Gly 35 40 <210> 7511 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7511 Cys Ala Arg Gly Asp Arg Gln Trp Leu Val Arg Asp Tyr Trp 1 5 10 <210> 7512 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7512 atgaccagga acacctccat aagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagaggg gatcggcagt ggctggtaag agactactgg 120 ggccaggga 129 <210> 7513 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7513 Met Thr Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp Arg 20 25 30 Gln Trp Leu Val Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 7514 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7514 atgaccagca acacctccat aagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagaggg gatcggcagt ggctggtaag agactactgg 120 ggccaggga 129 <210> 7515 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7515 Met Thr Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp Arg 20 25 30 Gln Trp Leu Val Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 7516 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7516 Cys Ala His Ser Val Pro Leu Leu Trp Phe Gly Glu Leu Tyr Gly Trp 1 5 10 15 Phe Asp Pro Trp 20 <210> 7517 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7517 caaaaaccag gtggtccttc aatgaccaac atggaccctg tggacacagc cacatattac 60 tgtgcacaca gcgtcccttt actatggttc ggggagttat atggttggtt cgacccctgg 120 ggccaggga 129 <210> 7518 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7518 Gln Lys Pro Gly Gly Pro Ser Met Thr Asn Met Asp Pro Val Asp Thr 1 5 10 15 Ala Thr Tyr Tyr Cys Ala His Ser Val Pro Leu Leu Trp Phe Gly Glu 20 25 30 Leu Tyr Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7519 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7519 aaaaaccagg tggtccttac aatgaccaac atggaccctg tggacacagc cacatattac 60 tgtgcacaca gcgtcccttt actatggttc ggggagttat atggttggtt cgacccctgg 120 ggccaggga 129 <210> 7520 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7520 Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr 1 5 10 15 Ala Thr Tyr Tyr Cys Ala His Ser Val Pro Leu Leu Trp Phe Gly Glu 20 25 30 Leu Tyr Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7521 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7521 Cys Ala Arg Asp Ser Glu Val Ala Ala Ala Gly Ile Tyr Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 7522 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7522 acagcctaca tggagctgag gagcctgaga tctgacgaca cggccgtgta ttactgtgcg 60 agagattctg aggtagcagc agctggtatt tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7523 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7523 Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Ser Glu Val Ala Ala Ala Gly Ile Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7524 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7524 aatgcctaca tggagctgag gagcctgaga tctgacgaca cggccgtgta ttactgtgcg 60 agagattctg aggtagcagc agctggtatt tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7525 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7525 Asn Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Ser Glu Val Ala Ala Ala Gly Ile Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7526 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7526 Cys Ala Arg Glu Arg Gly Pro Gly Tyr Phe Asp Tyr Trp 1 5 10 <210> 7527 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7527 accatgacca cagacacatc cacgagcaca gcctacatgg agctgaggag cctgagatct 60 gacgacacgg ccgtgtatta ctgtgcgaga gagaggggcc caggctactt tgactactgg 120 ggccaggga 129 <210> 7528 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7528 Thr Met Thr Thr Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg 1 5 10 15 Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Arg 20 25 30 Gly Pro Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7529 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7529 accatgacca cacacacatc cacgagcaca gcctacatgg agctgaggag cctgagatct 60 gacgacacgg ccgtgtatta ctgtgcgaga gagaggggcc caggctactt tgactactgg 120 ggccaggga 129 <210> 7530 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7530 Thr Met Thr Thr His Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg 1 5 10 15 Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Arg 20 25 30 Gly Pro Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7531 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7531 Cys Ala Arg His Leu Arg Tyr Tyr Asp Trp Arg Leu Asp Tyr Trp 1 5 10 15 <210> 7532 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7532 tccgtagaca cgtccaagaa tcagttctcc ctgaacctga ggtctgtgac cgccgcagac 60 acggctgtct attactgtgc gagacatcta cgatattatg actggagact tgactactgg 120 ggccaggga 129 <210> 7533 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7533 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Asn Leu Arg Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg His Leu Arg Tyr 20 25 30 Tyr Asp Trp Arg Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7534 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7534 tccgtagaca cgtccaagaa tcagttctcc ctgaacctga agtctgtgac cgccgcagac 60 gcggctgtct attactgtgc gagacatcta cgatattatg actggagact tgactactgg 120 ggccaggga 129 <210> 7535 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7535 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Asn Leu Lys Ser Val 1 5 10 15 Thr Ala Ala Asp Ala Ala Val Tyr Tyr Cys Ala Arg His Leu Arg Tyr 20 25 30 Tyr Asp Trp Arg Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7536 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7536 Cys Ala Lys Gly Asp Gly Glu Tyr Phe Gln His Trp 1 5 10 <210> 7537 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7537 ttcaccatct ccagagacaa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaggggacg gtgaatactt ccagcactgg 120 ggccagggc 129 <210> 7538 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7538 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly 20 25 30 Asp Gly Glu Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 7539 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7539 ttcaccatct ccagacacaa ttccaagaac acgctgtatc tgcaaatcaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaaggggacg gtgaatactt ccagcactgg 120 ggccagggc 129 <210> 7540 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7540 Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly 20 25 30 Asp Gly Glu Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 7541 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7541 Cys Ala Arg Glu Ser Ile Ala Val Gly Ser Arg Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 7542 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7542 agggacccgt ccttcagcac agcctacatg gaactgagca gtctgacatc tgacgacact 60 gtcgtctatt actgtgcgag agagtcaata gcagttggtt cgcgctactt tgactactgg 120 ggccagggg 129 <210> 7543 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7543 Arg Asp Pro Ser Phe Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Thr 1 5 10 15 Ser Asp Asp Thr Val Val Tyr Tyr Cys Ala Arg Glu Ser Ile Ala Val 20 25 30 Gly Ser Arg Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7544 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7544 agggacacgt ccttcagcac agcctacatg gagctgagca gtctggcatc tgacgacact 60 gtcgtatatt actgtgcgcg agagtcaata gcagttggtt cgcgctactt tgactactgg 120 ggccagggg 129 <210> 7545 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7545 Arg Asp Thr Ser Phe Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Ala 1 5 10 15 Ser Asp Asp Thr Val Val Tyr Tyr Cys Ala Arg Glu Ser Ile Ala Val 20 25 30 Gly Ser Arg Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7546 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7546 Cys Ala Arg Val Gln Val Gln Leu Glu Arg His Gly Val Gly Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 7547 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7547 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagtcc aggtacaact ggaacggcat ggggtagggt actacggtat ggacgtctgg 120 ggccagggg 129 <210> 7548 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7548 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Val Gln Val Gln Leu Glu Arg His Gly Val 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7549 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7549 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagtcc aggtacaact ggaacggcat ggggtagggt actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7550 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7550 Cys Ala His Lys Ile Trp Phe Arg Glu Leu Asp His Asp Ala Phe Asp 1 5 10 15 Ile Trp <210> 7551 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7551 acctccaaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacaagat atggttcagg gagttagatc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7552 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7552 Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Lys Ile Trp Phe Arg Glu Leu 20 25 30 Asp His Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7553 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7553 cacctccaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacaagat atggttcagg gagttagatc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7554 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7554 His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Lys Ile Trp Phe Arg Glu Leu 20 25 30 Asp His Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7555 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7555 Cys Ala Lys Val Ser Glu Tyr Gly Ser Gly Ser Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 7556 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7556 agagacaaca tcaaaaactc cctgtatctg caaatgaaca gtctgagaac tgaggacacc 60 gccttgtatt actgtgcaaa agtatcggag tatggttcgg ggagttattt tgactactgg 120 ggccaggga 129 <210> 7557 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7557 Arg Asp Asn Ile Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Thr Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Val Ser Glu Tyr Gly 20 25 30 Ser Gly Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7558 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7558 agagacaaca gcaaaaactc cctgtatctg caaatgaaca gtctgagaac tgaggacacc 60 gccttgtatt actgtgcaaa agtatcggag tatggttcgg ggagttattt tgactactgg 120 ggccaggga 129 <210> 7559 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7559 Arg Asp Asn Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Thr Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Val Ser Glu Tyr Gly 20 25 30 Ser Gly Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7560 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7560 Cys Thr Thr Asp Arg Ser Pro Arg Tyr Tyr Tyr Tyr Gly Met Asp Val 1 5 10 15 Trp <210> 7561 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7561 gatgattcaa aaaacacgct gtatctgcaa atgaacagcc tgaataccga ggacacagcc 60 gtgtattact gtaccacaga tcggtcgccc cgctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7562 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7562 Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Asn Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Asp Arg Ser Pro Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7563 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7563 gatgattcaa aaaacacgct gtatctgcaa atgaacagcc tgaaaaccga ggacacagcc 60 gtgtattact gtaccacaga tcggtcgccc cgctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7564 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7564 Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Asp Arg Ser Pro Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7565 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7565 Cys Ala Arg Glu Trp Met Thr Gly Pro Tyr Asn Trp Phe Asp Pro Trp 1 5 10 15 <210> 7566 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7566 agggacacat ccgcgagcac agcctacatg gagctgagca gcctgagctc tgatgacacg 60 gctgtgtatt tctgtgcgag ggagtggatg actggaccgt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 7567 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7567 Arg Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Ser 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Phe Cys Ala Arg Glu Trp Met Thr Gly 20 25 30 Pro Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7568 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7568 agggacacat ccgcgagcac agcctacatg gagctgagca gcctgagctc tgacgacacg 60 gctgtgtatt tctgtgcgag ggagtggatg actggaccgt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 7569 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7569 Cys Ala Arg Tyr Gly Tyr Tyr Asp Ser Ser Gly Pro Phe Trp Gly Thr 1 5 10 15 Ser Trp Phe Asp Pro Trp 20 <210> 7570 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7570 cagttctccc tgaagttgag ctctgtgacc gccgcagaca cggccgtgta ttactgtgcg 60 agatatggtt actatgatag tagtggacca ttttggggaa cttcctggtt cgacccctgg 120 ggccaggga 129 <210> 7571 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7571 Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Tyr Gly Tyr Tyr Asp Ser Ser Gly Pro Phe Trp 20 25 30 Gly Thr Ser Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7572 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7572 cagttctccc tgaagttgag ccctgtgacc gccgcagaca cggccgtgta ctactgtgcg 60 agatatggtt actatgatag tagtggacca ttttggggaa cttcctggtt cgacccctgg 120 ggccaggga 129 <210> 7573 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7573 Gln Phe Ser Leu Lys Leu Ser Pro Val Thr Ala Ala Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Tyr Gly Tyr Tyr Asp Ser Ser Gly Pro Phe Trp 20 25 30 Gly Thr Ser Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7574 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7574 Cys Ala Arg Ile Gly Tyr Gly Asp Cys Leu Ser Asp Tyr Trp 1 5 10 <210> 7575 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7575 catctccaag gacacctcca aaaccaggtg gtccttacaa tgaccaacat ggaccctgtg 60 gacacagcca cgtattactg tgcacggata ggctacggtg actgcctatc tgactactgg 120 ggccaggga 129 <210> 7576 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7576 His Leu Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Gly Tyr 20 25 30 Gly Asp Cys Leu Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 7577 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7577 atctccaagg acacctccaa aaaccaggtg gtccttacaa tgaccaacat ggaccctgtg 60 gacacagcca cgtattactg tgcacggata ggctacggtg actgcctatc tgactactgg 120 ggccaggga 129 <210> 7578 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7578 Ile Ser Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Gly Tyr 20 25 30 Gly Asp Cys Leu Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 7579 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7579 Cys Ala Arg Asp Pro Tyr Gly Asp Leu Leu Leu Gly Leu Asp Tyr Trp 1 5 10 15 <210> 7580 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7580 tgggacacat ccgcgagcac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 gctgtgtatt actgtgcgag agatccctac ggtgacttac tacttggtct ggactactgg 120 ggccaggga 129 <210> 7581 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7581 Trp Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro Tyr Gly Asp 20 25 30 Leu Leu Leu Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7582 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7582 agggacacat ccgcgagcac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 gctgtgtatt actgtgcgag agatccctac ggtgacttac tacttggtct ggactactgg 120 ggccaggga 129 <210> 7583 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7583 Arg Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro Tyr Gly Asp 20 25 30 Leu Leu Leu Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7584 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7584 Cys Ala Ile Glu Gly Tyr Cys Ser Ser Thr Ser Cys Ser Gly Ala Phe 1 5 10 15 Asp Ile Trp <210> 7585 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7585 tccaagaact cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcca ttgaaggata ttgtagtagt accagctgct ccggagcttt tgatatctgg 120 ggccaaggg 129 <210> 7586 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7586 Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Ile Glu Gly Tyr Cys Ser Ser Thr Ser 20 25 30 Cys Ser Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7587 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7587 tccaagaaca cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcca ttgaaggata ttgtagtagt accagctgct ccggagcttt tgatatctgg 120 ggccaaggg 129 <210> 7588 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7588 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Ile Glu Gly Tyr Cys Ser Ser Thr Ser 20 25 30 Cys Ser Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7589 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7589 Cys Ala Arg Ile Ser Trp Tyr Asn Ser Thr Trp Ser Leu Asp Tyr Trp 1 5 10 15 <210> 7590 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7590 agggacaacg ccaagaactc gctgtatttg caaatgaaca gcctgagagc cgaggacacg 60 gccgtctatt actgtgcgag aataagctgg tataacagca cttggtccct tgactactgg 120 ggccaggga 129 <210> 7591 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7591 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ile Ser Trp Tyr Asn 20 25 30 Ser Thr Trp Ser Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7592 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7592 agggacaacg ccaagaaccc gctgtatttg caaatgaaca gcctgagagc cgaggacacg 60 gccgtctatt actgtgcgag aataagctgg tataacagca cttggtccct tgactactgg 120 ggccaggga 129 <210> 7593 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7593 Arg Asp Asn Ala Lys Asn Pro Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ile Ser Trp Tyr Asn 20 25 30 Ser Thr Trp Ser Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7594 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7594 Cys Ala Gly Ala Asp Lys Pro Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 1 5 10 15 <210> 7595 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7595 tgggacatgc ccacaagcac agcctacatg gagctgagca gcctgagatc cgaggacacg 60 gccgtgtatt actgtgcggg agcggataag ccttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7596 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7596 Trp Asp Met Pro Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Gly Ala Asp Lys Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7597 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7597 agggacatgt ccacaagcac agcctacatg gagctgagca gcctgagatc cgaggacacg 60 gccgtgtatt actgtgcggg agcggataag ccttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7598 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7598 Arg Asp Met Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Gly Ala Asp Lys Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7599 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7599 Cys Ala Lys Asp Gln Met Gly Ala Thr Asp Tyr Trp 1 5 10 <210> 7600 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7600 ttcaccatct ccagatataa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagatcaaa tgggagctac tgactactgg 120 ggccaggga 129 <210> 7601 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7601 Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp 20 25 30 Gln Met Gly Ala Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 7602 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7602 ttcaccatct ccagagataa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagatcaaa tgggagctac tgactactgg 120 ggccaggga 129 <210> 7603 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7603 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp 20 25 30 Gln Met Gly Ala Thr Asp Tyr Trp Gly Gln Gly 35 40 <210> 7604 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7604 Cys Ala Arg Val Ala Ser Ser Ser Trp Tyr Ser Pro Lys Ile Asp Val 1 5 10 15 Val Tyr Asp Tyr Trp 20 <210> 7605 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7605 tgcacagtct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagtgg ccagcagcag ctggtactcc ccgaagattg atgtggtata tgactactgg 120 ggccaggga 129 <210> 7606 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7606 Cys Thr Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Val Ala Ser Ser Ser Trp Tyr Ser Pro Lys 20 25 30 Ile Asp Val Val Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 7607 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7607 agcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagtgg ccagcagcag ctggtactcc ccgaagattg atgtggtata tgactactgg 120 ggccaggga 129 <210> 7608 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7608 Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Val Ala Ser Ser Ser Trp Tyr Ser Pro Lys 20 25 30 Ile Asp Val Val Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 7609 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7609 Cys Ala Lys Val Gly Gly Trp Gly Met Asp Val Trp 1 5 10 <210> 7610 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7610 ttcaccatct ccagagacaa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagtcgggg gatggggtat ggacgtctgg 120 ggccaaggg 129 <210> 7611 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7611 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val 20 25 30 Gly Gly Trp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7612 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7612 ttcaccatct ccagacacaa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagtcgggg gatggggtat ggacgtctgg 120 ggccaaggg 129 <210> 7613 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7613 Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val 20 25 30 Gly Gly Trp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7614 <211> 31 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7614 Cys Ala Arg His Gly Trp Asn Asp Pro Phe Pro Val Thr Gly Tyr Ser 1 5 10 15 Ser Ser Trp Tyr Pro Leu Asp Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 30 <210> 7615 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7615 accgccgcag acacggctgt gtattactgt gcgagacatg ggtggaatga cccgtttccg 60 gtcaccgggt atagcagcag ctggtacccc ctcgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7616 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7616 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg His Gly Trp Asn 1 5 10 15 Asp Pro Phe Pro Val Thr Gly Tyr Ser Ser Ser Trp Tyr Pro Leu Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7617 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7617 ccgccgcaga ccacggctgt gtattactgt gcgagacatg ggtggaatga cccgtttccg 60 gtcaccgggt atagcagcag ctggtacccc ctcgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7618 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7618 Pro Pro Gln Thr Thr Ala Val Tyr Tyr Cys Ala Arg His Gly Trp Asn 1 5 10 15 Asp Pro Phe Pro Val Thr Gly Tyr Ser Ser Ser Trp Tyr Pro Leu Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7619 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7619 Cys Ala Arg Arg Ala Ser Arg Arg Gly Ala Phe Asp Ile Trp 1 5 10 <210> 7620 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7620 atgaccacag acacatccac gagtacagcc tacatggagc tgaggagcct gagatctgac 60 gacacggccg tgtattactg tgcgagacgg gcctctagga ggggagcttt tgatatctgg 120 ggccaaggg 129 <210> 7621 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7621 Met Thr Thr Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser 1 5 10 15 Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Arg Ala Ser 20 25 30 Arg Arg Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7622 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7622 atgaccacag acacatccac gagcacagcc tacatggagc tgaggagcct gagatctgac 60 gacacggccg tgtattactg tgcgagacgg gcctctagga ggggagcttt tgatatctgg 120 ggccaaggg 129 <210> 7623 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7623 Cys Ala Arg Glu Ser Lys Thr Thr Val Thr Thr Leu Gly Tyr Trp 1 5 10 15 <210> 7624 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7624 accacagaca catccacgag cacagcctac atggagctga ggagcctgag atctgacgac 60 acggccgtgt attactgtgc gagagaaagc aaaactacgg tgactacgtt aggctactgg 120 ggccaggga 129 <210> 7625 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7625 Thr Thr Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu 1 5 10 15 Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Ser Lys Thr 20 25 30 Thr Val Thr Thr Leu Gly Tyr Trp Gly Gln Gly 35 40 <210> 7626 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7626 accacagaca catccacgag cacagcctac atggagctga ggagcctgag atctgacgac 60 acggccgtgc attactgtgc gagagaaagc aaaactacgg tgactacgtt aggctactgg 120 ggccaggga 129 <210> 7627 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7627 Thr Thr Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu 1 5 10 15 Arg Ser Asp Asp Thr Ala Val His Tyr Cys Ala Arg Glu Ser Lys Thr 20 25 30 Thr Val Thr Thr Leu Gly Tyr Trp Gly Gln Gly 35 40 <210> 7628 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7628 Cys Ala Arg Glu Gly Arg Glu Ala Ala Ala Gly Thr Asn Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 7629 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7629 tgcacagcct acttggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagagg gcagggaagc agcagctggt acgaactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7630 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7630 Cys Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Gly Arg Glu Ala Ala Ala Gly Thr Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7631 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7631 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcgagagagg gcagggaagc agcagctggt acgaactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7632 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7632 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Gly Arg Glu Ala Ala Ala Gly Thr Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7633 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7633 Cys Ala Arg Gly Pro Glu Trp Phe Ala Asn Tyr Tyr Tyr Gly Met Asp 1 5 10 15 Val Trp <210> 7634 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7634 acgtccaaga accagttctc cctgaggctg agctctgtga ccgccgcgga cacggccgtg 60 tattactgtg cgagaggtcc ggagtggttt gccaactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7635 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7635 Thr Ser Lys Asn Gln Phe Ser Leu Arg Leu Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Pro Glu Trp Phe Ala Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7636 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7636 acgtccaaga accagttctc cctgaagctg agctctgtga ccgccgcgga cacggccgtg 60 tattactgtg cgagaggtcc ggagtggttt gccaactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7637 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7637 Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Pro Glu Trp Phe Ala Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7638 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7638 Cys Ala Lys Gly Gln Gly Asp Ala Thr Thr Val Thr Pro Phe Asp Tyr 1 5 10 15 Trp <210> 7639 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7639 gacaattcca agaacacgct gtatctgcaa atgaatagcc tgagagccga ggacacggcc 60 atatattact gtgcgaaagg gcaaggggat gcgactacgg tgaccccctt tgactactgg 120 ggccaggga 129 <210> 7640 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7640 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Lys Gly Gln Gly Asp Ala Thr 20 25 30 Thr Val Thr Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7641 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7641 gacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 atatattact gtgcgaaagg gcaaggggat gcgactacgg tgaccccctt tgactactgg 120 ggccaggga 129 <210> 7642 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7642 Cys Ala Arg Gln Pro Gln Tyr Tyr Tyr Gly Ala Gly Phe Asp Pro Trp 1 5 10 15 <210> 7643 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7643 gccgacaagt ccatcagcac cgcctacctg cagtggagca gcctgaaggc ctcggacacc 60 gccatttact attgtgcgag acagccccaa tattactatg gtgcggggtt cgacccctgg 120 ggccaggga 129 <210> 7644 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7644 Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys 1 5 10 15 Ala Ser Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Gln Pro Gln Tyr Tyr 20 25 30 Tyr Gly Ala Gly Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7645 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7645 gacgacaagt ccatcagcac cgcctacctg cagtggagca gcctgaaggc ctctgacacc 60 gccatttact attgtgcgag acagccccaa tattactatg gtgcggggtt cgacccctgg 120 ggccaggga 129 <210> 7646 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7646 Asp Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys 1 5 10 15 Ala Ser Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Gln Pro Gln Tyr Tyr 20 25 30 Tyr Gly Ala Gly Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7647 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7647 Cys Ala His Leu Gln Ser Gly Tyr Asp Ser Ile Leu Asp Tyr Trp 1 5 10 15 <210> 7648 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7648 caccaaggac acctccaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacat attactgtgc acaccttcaa agtggctacg attcaatttt ggactactgg 120 ggccaggga 129 <210> 7649 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7649 His Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Leu Gln Ser Gly 20 25 30 Tyr Asp Ser Ile Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7650 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7650 accaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacat attactgtgc acaccttcaa agtggctacg attcaatttt ggactactgg 120 ggccaggga 129 <210> 7651 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7651 Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Leu Gln Ser Gly 20 25 30 Tyr Asp Ser Ile Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7652 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7652 Cys Ala Ala Asp Gly Phe Gly Ile Val Gly Ala Thr Asn Asn Tyr Phe 1 5 10 15 Asp Tyr Trp <210> 7653 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7653 tccacaagca cagcctacat ggagctgagc agcctgagat ccgaggacac ggccgtgtat 60 tactgtgcgg cagacgggtt cggtatagtg ggagctacta acaactactt tgactactgg 120 ggccaggga 129 <210> 7654 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7654 Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Ala Asp Gly Phe Gly Ile Val Gly Ala 20 25 30 Thr Asn Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7655 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7655 tccacaagca cagcctacat ggagctgagc agcctgagat ccgaggacac ggccgtatat 60 tactgtgcgg cagacgggtt cggtatagtg ggagctacta acaactactt tgactactgg 120 ggccaggga 129 <210> 7656 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7656 Cys Ala Arg Gly Tyr Cys Ser Gly Gly Ser Cys Tyr Phe Ser Pro Gly 1 5 10 15 Leu Gly Gly Val Asp Trp 20 <210> 7657 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7657 cagttctccc tgaagctgag ctctgtgact gccgcggaca cggccgtgta ttactgtgcg 60 agaggatatt gtagtggtgg tagctgctat ttttcgccgg gtctcggggg tgtggactgg 120 ggccaggga 129 <210> 7658 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7658 Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Gly Tyr Cys Ser Gly Gly Ser Cys Tyr Phe Ser 20 25 30 Pro Gly Leu Gly Gly Val Asp Trp Gly Gln Gly 35 40 <210> 7659 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7659 cagttctccc tgaagctgag ctctgtgact gccgcggaca cggccgtgta ttactgtgcg 60 agaggatatt gtagtggtgg tagctgctat ttttcgccgg gtctcggggg tgtagactgg 120 ggccaggga 129 <210> 7660 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7660 Cys Ala Arg Gly Leu Leu Arg Asp Ile Leu Thr Gly Tyr Leu Pro Pro 1 5 10 15 Leu Gly Tyr Trp 20 <210> 7661 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7661 aagaactcac tgtatctgca aatgaacagc ctgagagacg aggacacggc tgtgtattac 60 tgtgcgagag ggcttctacg ggatattttg actggttatc tccccccttt ggggtactgg 120 ggccgggga 129 <210> 7662 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7662 Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Leu Leu Arg Asp Ile Leu Thr Gly 20 25 30 Tyr Leu Pro Pro Leu Gly Tyr Trp Gly Arg Gly 35 40 <210> 7663 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7663 aagaactcac tgtatctgca aatgaacagc ctgagagacg aggacacggc tgtgtattac 60 tgtgcgagag gacttctacg ggatattttg actggttatc tccccccttt ggggtactgg 120 ggccaggga 129 <210> 7664 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7664 Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Leu Leu Arg Asp Ile Leu Thr Gly 20 25 30 Tyr Leu Pro Pro Leu Gly Tyr Trp Gly Gln Gly 35 40 <210> 7665 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7665 Cys Thr Arg Pro Ala Glu Asn Tyr Tyr Gly Ser Gly Ser Tyr Gly Tyr 1 5 10 15 Trp <210> 7666 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7666 gatgattcaa tcaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagacc cgcggaaaat tactatggtt cggggagtta tggctactgg 120 ggccaggga 129 <210> 7667 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7667 Asp Asp Ser Ile Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Pro Ala Glu Asn Tyr Tyr 20 25 30 Gly Ser Gly Ser Tyr Gly Tyr Trp Gly Gln Gly 35 40 <210> 7668 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7668 gatgattcaa agaacacggc gtatctgcaa atgaacagcc tgaaaaccga ggacacggcc 60 gtgtattact gtactagacc cgcggaaaat tactatggtt cggggagtta tggctactgg 120 ggccaggga 129 <210> 7669 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7669 Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg Pro Ala Glu Asn Tyr Tyr 20 25 30 Gly Ser Gly Ser Tyr Gly Tyr Trp Gly Gln Gly 35 40 <210> 7670 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7670 Cys Ala His Gly Ser Gly Trp Thr Thr Phe Asp Tyr Trp 1 5 10 <210> 7671 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7671 caccatcacc aaggacacct ccaaaaccag gtggtcctta caatgaccaa catggaccct 60 gtggacacag ccacatatta ctgtgcacac ggcagtggct ggaccacctt tgactactgg 120 ggccaggga 129 <210> 7672 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7672 His His His Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Ser 20 25 30 Gly Trp Thr Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7673 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7673 accatcacca aggacacctc caaaaaccag gtggtcctta caatgaccaa catggaccct 60 gtggacacag ccacatatta ctgtgcacac ggcagtggct ggaccacctt tgactactgg 120 ggccaggga 129 <210> 7674 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7674 Thr Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Ser 20 25 30 Gly Trp Thr Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7675 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7675 Cys Ala Arg Glu Glu Arg Ile Trp Trp Glu Leu Leu Gly Tyr Phe Gln 1 5 10 15 His Trp <210> 7676 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7676 acgtccatca gtacagccta catggagctg agcaggctga gatctgacga cacggccgtg 60 tattactgtg cgagagaaga gaggatctgg tgggagctac tcggatactt ccagcactgg 120 ggccagggc 129 <210> 7677 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7677 Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg Ser Asp 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Glu Arg Ile Trp Trp Glu 20 25 30 Leu Leu Gly Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 7678 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7678 acgtccatca gcacagccta catggagctg agcaggctga gatctgacga cacggccgtg 60 tattactgtg cgagagaaga gaggatctgg tgggagctac tcggatactt ccagcactgg 120 ggccagggc 129 <210> 7679 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7679 Cys Ala Lys Asp Ile Gly Val Ile Trp Gln Tyr Gly Met Asp Val Trp 1 5 10 15 <210> 7680 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7680 agagacaacg ccaagaactc cctgtatctg caaatgaaca gtctgagagc tgaggacacg 60 gccttgtatt actgtgcaaa agatattggg gtgatatggc agtacggtat ggacgtttgg 120 ggccaaggg 129 <210> 7681 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7681 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Ile Gly Val Ile 20 25 30 Trp Gln Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7682 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7682 agagacaacg ccaagaactc cctgtatctg caaatgaaca gtctgagagc tgaggacacg 60 gccttgtatt actgtgcaaa agatattggg gtgatatggc agtacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7683 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7683 Cys Ala Arg Gly Arg Gly Pro Tyr Ile Val Val Val Val Ala Ala Pro 1 5 10 15 Ser Arg Trp Phe Asp Pro Trp 20 <210> 7684 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7684 ttctccctga agctgagctt tgtgaccgcc gcggacacgg ctgtgtatta ctgtgcgaga 60 ggccggggcc cttatattgt agtggtggta gctgccccct cgaggtggtt cgacccctgg 120 ggccaggga 129 <210> 7685 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7685 Phe Ser Leu Lys Leu Ser Phe Val Thr Ala Ala Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Gly Arg Gly Pro Tyr Ile Val Val Val Val Ala Ala 20 25 30 Pro Ser Arg Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7686 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7686 ttctccctga agctgagctc tgtgaccgcc gcggacacgg ctgtgtatta ctgtgcgaga 60 ggccggggcc cttatattgt agtggtggta gctgccccct cgaggtggtt cgacccctgg 120 ggccaggga 129 <210> 7687 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7687 Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Gly Arg Gly Pro Tyr Ile Val Val Val Val Ala Ala 20 25 30 Pro Ser Arg Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7688 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7688 Cys Thr Thr Glu Leu Gly Tyr Cys Thr Ser Pro Ser Cys Ser Tyr Trp 1 5 10 15 <210> 7689 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7689 agagatgact caaaaaacac gctgtatctg caaatgaaca gcctgaagac cgacgacaca 60 gccatatatt actgtaccac agagttaggg tattgtacta gtcccagctg ctcttactgg 120 ggccaggga 129 <210> 7690 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7690 Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys 1 5 10 15 Thr Asp Asp Thr Ala Ile Tyr Tyr Cys Thr Thr Glu Leu Gly Tyr Cys 20 25 30 Thr Ser Pro Ser Cys Ser Tyr Trp Gly Gln Gly 35 40 <210> 7691 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7691 agagatgact caaaaaacac gctgtatctg caaatgaaca gcctgaaaac cgacgacaca 60 gccatatatt actgtaccac agagttaggg tattgtacta gtcccagctg ctcttactgg 120 ggccaggga 129 <210> 7692 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7692 Cys Ala Arg Gly Gly Cys Gly Gly Asp Cys Ser Asp Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 7693 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7693 tacaacacgc tgtatcttca aatgaacagc ctgagagccg aggacacggc cgtgtattac 60 tgtgcgagag ggggttgtgg tggtgattgc tcagactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7694 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7694 Tyr Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Gly Cys Gly Gly Asp Cys Ser Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7695 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7695 aagaacacgc tgtatcttca aatgaacagc ctgagagccg aggacacggc cgtgtattac 60 tgtgcgagag ggggttgtgg tggtgattgc tcagactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7696 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7696 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Gly Cys Gly Gly Asp Cys Ser Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7697 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7697 Cys Ala Arg Asp Gln Arg Tyr Arg Ser Ser Ser His Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 7698 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7698 aacacgctgt atcttcaaat gaacagcctg agagccgagg acacggccgt gtattactgt 60 gcgagagatc agcggtatag gagcagctcc cactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7699 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7699 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Gln Arg Tyr Arg Ser Ser Ser His Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7700 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7700 tacacgctgt atcttcaaat gaacagcctg agagccgagg acacggccgt gtattactgt 60 gcgagagatc agcggtatag gagcagctcc cactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7701 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7701 Tyr Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Gln Arg Tyr Arg Ser Ser Ser His Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7702 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7702 Cys Ala Gln Thr Ala Gly Ser Arg Arg Pro Phe Asp Ser Trp 1 5 10 <210> 7703 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7703 catcaccaag gacacctcca aaatgaggtg gtcctcacaa tgaccaacat ggaccctgtg 60 gacacagcca catatcactg tgcacagacg gcgggctccc gaagaccatt tgactcctgg 120 ggccaggga 129 <210> 7704 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7704 His His Gln Gly His Leu Gln Asn Glu Val Val Leu Thr Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr His Cys Ala Gln Thr Ala Gly 20 25 30 Ser Arg Arg Pro Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 7705 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7705 atcaccaagg acacctccaa aaatgaggtg gtcctcacaa tgaccaacat ggaccctgtg 60 gacacagcca catatcactg tgcacagacg gcgggctccc gaagaccatt tgactcctgg 120 ggccaggga 129 <210> 7706 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7706 Ile Thr Lys Asp Thr Ser Lys Asn Glu Val Val Leu Thr Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr His Cys Ala Gln Thr Ala Gly 20 25 30 Ser Arg Arg Pro Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 7707 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7707 Cys Ala Arg Asp Arg Asp Ile Ala Ala Ala Gly Thr His Asp Tyr Trp 1 5 10 15 <210> 7708 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7708 agagacaacg ccaagaacac gctgtatctg caaatgaaca gtctgagagc cgaggacacg 60 gctgtgtatt actgtgcaag agatagggat atagcagcag ctggtacgca tgactactgg 120 ggccaggga 129 <210> 7709 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7709 Arg Asp Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Asp Ile Ala 20 25 30 Ala Ala Gly Thr His Asp Tyr Trp Gly Gln Gly 35 40 <210> 7710 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7710 gatcacaacg ccaagaacac gctgtatctg caaatgaaca gtctgagagc cgaggacacg 60 gctgtgtatt actgtgcaag agatagggat atagcagcag ctggtacgca tgactactgg 120 ggccaggga 129 <210> 7711 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7711 Asp His Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Asp Ile Ala 20 25 30 Ala Ala Gly Thr His Asp Tyr Trp Gly Gln Gly 35 40 <210> 7712 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7712 Cys Ala Arg Gly His Asp Ser Ser Arg Ser Tyr Gly Met Asp Val Trp 1 5 10 15 <210> 7713 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7713 tggaacacct ccataagcac agcctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag aggccacgac agcagccgga gctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7714 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7714 Trp Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly His Asp Ser Ser 20 25 30 Arg Ser Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7715 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7715 aggaacacct ccataagcac agcctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag aggccacgac agcagccgga gctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7716 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7716 Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly His Asp Ser Ser 20 25 30 Arg Ser Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7717 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7717 Cys Ala Arg Ile Phe Gly Tyr Asn Ser Phe Asp Tyr Trp 1 5 10 <210> 7718 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7718 accatctcca aggacgcctc caaaaaccag gtggtcctta caatgaccaa catggaccct 60 gtggacacag ccacgtatta ctgtgcgcgg atatttggct acaattcgtt tgactactgg 120 ggccaggga 129 <210> 7719 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7719 Thr Ile Ser Lys Asp Ala Ser Lys Asn Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Phe 20 25 30 Gly Tyr Asn Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7720 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7720 accatctcca aggacacctc caaaaaccag gtggtcctta caatgaccaa catggaccct 60 gtggacacag ccacgtatta ctgtgcacgg atatttggct acaattcgtt tgactactgg 120 ggccaggga 129 <210> 7721 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7721 Thr Ile Ser Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Phe 20 25 30 Gly Tyr Asn Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7722 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7722 Cys Ala Lys Val Pro Ile Thr Met Val Arg Gly Val Arg Arg Asn His 1 5 10 15 Asn Trp Phe Asp Pro Trp 20 <210> 7723 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7723 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaggttccca ttactatggt tcggggagtc cgccgaaacc acaactggtt cgacccctgg 120 ggccaggga 129 <210> 7724 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7724 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Val Pro Ile Thr Met Val Arg Gly Val Arg Arg 20 25 30 Asn His Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7725 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7725 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaggttccca ttactatggt tcggggagtc cgccgaaacc acaactggtt cgacccctgg 120 ggccaggga 129 <210> 7726 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7726 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Val Pro Ile Thr Met Val Arg Gly Val Arg Arg 20 25 30 Asn His Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7727 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7727 Cys Ala Lys Ala Met Thr Thr Val Thr Thr Gly Tyr Trp Gly Phe Asp 1 5 10 15 Asn Trp <210> 7728 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7728 aacgccaaga agtctctgta tctgcaaatg aacagtctga gagctgagga cacggccttg 60 tattactgtg caaaagccat gactaccgtg accacgggtt attggggctt tgacaactgg 120 ggccaggga 129 <210> 7729 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7729 Asn Ala Lys Lys Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Ala Met Thr Thr Val Thr Thr 20 25 30 Gly Tyr Trp Gly Phe Asp Asn Trp Gly Gln Gly 35 40 <210> 7730 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7730 aacgccaaga actctctgta tctgcaaatg aacagtctga gagctgagga cacggccttg 60 tattactgtg caaaagccat gactacggtg actacgggtt attggggctt tgacaactgg 120 ggccaggga 129 <210> 7731 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7731 Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Ala Met Thr Thr Val Thr Thr 20 25 30 Gly Tyr Trp Gly Phe Asp Asn Trp Gly Gln Gly 35 40 <210> 7732 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7732 Cys Ala Arg His Trp Tyr Ser Ser Gly Leu Lys Arg Val Gly Asn Tyr 1 5 10 15 Phe Asp Tyr Trp 20 <210> 7733 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7733 caagaaccag tctccctgaa gctgagctct gtgaccgccg cagacacggc tgtgtattac 60 tgtgcgagac actggtatag cagtggatta aaaagggtgg ggaactactt tgactactgg 120 ggccaggga 129 <210> 7734 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7734 Gln Glu Pro Val Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg His Trp Tyr Ser Ser Gly Leu Lys Arg 20 25 30 Val Gly Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7735 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7735 aagaaccagt tctccctgaa gctgagctct gtgaccgccg cagacacggc tgtgtattac 60 tgtgcgagac actggtatag cagtggatta aaaagggtgg ggaactactt tgactactgg 120 ggccaggga 129 <210> 7736 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7736 Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg His Trp Tyr Ser Ser Gly Leu Lys Arg 20 25 30 Val Gly Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7737 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7737 Cys Ala Ser Glu Ala Cys Ser Ser Thr Ser Cys Tyr Ser Gly Thr Ala 1 5 10 15 His Asp Tyr Trp 20 <210> 7738 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7738 acgagcacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattgc 60 tgtgcgagtg aagcttgtag tagtaccagc tgctattcgg gtacagctca tgactactgg 120 ggccaggga 129 <210> 7739 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7739 Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Cys Cys Ala Ser Glu Ala Cys Ser Ser Thr Ser Cys Tyr 20 25 30 Ser Gly Thr Ala His Asp Tyr Trp Gly Gln Gly 35 40 <210> 7740 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7740 acgagcacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagtg aagcttgtag tagtaccagc tgctattcgg gtacagctca tgactactgg 120 ggccaggga 129 <210> 7741 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7741 Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Ser Glu Ala Cys Ser Ser Thr Ser Cys Tyr 20 25 30 Ser Gly Thr Ala His Asp Tyr Trp Gly Gln Gly 35 40 <210> 7742 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7742 Cys Ala Arg Asn Val Glu Arg Asn Ala Phe Asp Ile Trp 1 5 10 <210> 7743 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7743 caccatctcc aaggacacct ccaaaaccag gtggtcctta caatgaccaa catggaccct 60 gtggacacag ccacgtatta ctgtgcacgg aacgtagaga gaaatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7744 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7744 His His Leu Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Asn Val 20 25 30 Glu Arg Asn Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7745 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7745 accatctcca aggacacctc caaaaaccag gtggtcctta caatgaccaa catggaccct 60 gtggacacag ccacgtatta ctgtgcacgg aacgtagaga gaaatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7746 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7746 Thr Ile Ser Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Asn Val 20 25 30 Glu Arg Asn Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7747 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7747 Cys Val Lys Gly Thr Phe Ser Thr Thr Leu Gly Thr His Leu Asp Ser 1 5 10 15 Trp <210> 7748 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7748 gacgacgcca ataactccct gtttctacaa atgaacagtc tgagaagtga ggacacggcc 60 ctctattcct gtgtaaaagg gacatttagc accaccttgg ggacccacct tgactcctgg 120 ggccaggga 129 <210> 7749 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7749 Asp Asp Ala Asn Asn Ser Leu Phe Leu Gln Met Asn Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Leu Tyr Ser Cys Val Lys Gly Thr Phe Ser Thr Thr 20 25 30 Leu Gly Thr His Leu Asp Ser Trp Gly Gln Gly 35 40 <210> 7750 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7750 gacgacgcca agaactccct gtttctacaa atgaacagtc tgagaagtga ggacacggcc 60 ctctattcct gtgtaaaagg gacatttagc accaccttgg ggacccacct tgactcctgg 120 ggccaggga 129 <210> 7751 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7751 Asp Asp Ala Lys Asn Ser Leu Phe Leu Gln Met Asn Ser Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Leu Tyr Ser Cys Val Lys Gly Thr Phe Ser Thr Thr 20 25 30 Leu Gly Thr His Leu Asp Ser Trp Gly Gln Gly 35 40 <210> 7752 <211> 27 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7752 Cys Ala Lys Gly Gly Thr Asp Arg Ile Ala Ala Ala Gly Pro Pro Arg 1 5 10 15 Pro Gly Asp Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 7753 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7753 ttgaacagcc tgagagccga ggacacggcc gtatattact gcgcgaaagg agggacggac 60 cgtatagcag cagctggacc accccgcccc ggtgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7754 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7754 Leu Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 1 5 10 15 Gly Gly Thr Asp Arg Ile Ala Ala Ala Gly Pro Pro Arg Pro Gly Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7755 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7755 atgaacagcc tgagagccga ggacacggcc gtatattact gtgcgaaagg agggacggac 60 cgtatagcag cagctggacc accccgcccc ggtgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7756 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7756 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 1 5 10 15 Gly Gly Thr Asp Arg Ile Ala Ala Ala Gly Pro Pro Arg Pro Gly Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7757 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7757 Cys Ala Arg Gly Ala Tyr Cys Gly Gly Asp Cys Leu Val Phe Leu Arg 1 5 10 15 Asn Leu Phe Ser Trp Phe Asp Pro Trp 20 25 <210> 7758 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7758 ttggagctga gcagcctgag atctgaggac acggccgtgt attactgtgc gagaggggca 60 tattgtggtg gtgactgctt agtattccta cggaatctct tcagctggtt cgacccctgg 120 ggccaggga 129 <210> 7759 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7759 Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Ala Tyr Cys Gly Gly Asp Cys Leu Val Phe Leu Arg Asn 20 25 30 Leu Phe Ser Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7760 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7760 atggagctga gcagcctgag atctgaggac acggccgtgt attactgtgc gagaggggca 60 tattgtggtg gtgactgctt agtattccta cggaatctct tcagctggtt cgacccctgg 120 ggccaggga 129 <210> 7761 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7761 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Ala Tyr Cys Gly Gly Asp Cys Leu Val Phe Leu Arg Asn 20 25 30 Leu Phe Ser Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7762 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7762 Cys Ala Ser Ile Ala Tyr Ser Ser Ser Arg Tyr Gly Leu Tyr Ala Phe 1 5 10 15 Asp Ile Trp <210> 7763 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7763 gccaagaact cgctgtatct gcaaatgaac agtctgagag ccgaggacac ggctgtgtat 60 tactgtgcaa gtatcgcgta tagcagcagc cggtacgggt tgtatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7764 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7764 Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Ser Ile Ala Tyr Ser Ser Ser Arg Tyr 20 25 30 Gly Leu Tyr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7765 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7765 gccaagaaca cgctgtatct gcaaatgaac agtctgagag ccgaggacac ggctgtgtat 60 tactgtgcaa gtatcgcgta tagcagcagc cggtacgggt tgtatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7766 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7766 Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Ser Ile Ala Tyr Ser Ser Ser Arg Tyr 20 25 30 Gly Leu Tyr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7767 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7767 Cys Thr Thr Asp Arg Trp Tyr Ser Ser Ser Trp Gly Ser Gly Gly Phe 1 5 10 15 Asp Tyr Trp <210> 7768 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7768 tcaaaaagca cgctgtatct gcaaatgaac agcctgaaaa ccgaggacac agccgtgtgt 60 tactgtacca cagataggtg gtatagcagc agctggggat cggggggctt tgactactgg 120 ggccaggga 129 <210> 7769 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7769 Ser Lys Ser Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Cys Tyr Cys Thr Thr Asp Arg Trp Tyr Ser Ser Ser Trp 20 25 30 Gly Ser Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7770 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7770 tcaaaaaaca cgctgtatct gcaaatgaac agcctgaaaa ccgaggacac agccgtgtat 60 tactgtacca cagataggtg gtatagcagc agctggggat cggggggctt tgactactgg 120 ggccaggga 129 <210> 7771 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7771 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Thr Asp Arg Trp Tyr Ser Ser Ser Trp 20 25 30 Gly Ser Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7772 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7772 Cys Ala Lys Asp Leu Ser Val Trp Gln Trp Leu Val Leu Gly Phe Asp 1 5 10 15 Tyr Trp <210> 7773 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7773 aattccaaga acacgctgta tctgcaaatg aacagcctgg gagccgagga cacggccgta 60 tattactgtg cgaaagatct ttccgtatgg cagtggctgg tgctgggctt tgattactgg 120 ggccaggga 129 <210> 7774 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7774 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Gly Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Ser Val Trp Gln Trp 20 25 30 Leu Val Leu Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7775 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7775 aattccaaga acacgctgta tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgaaagatct ttccgtatgg cagtggctgg tgctgggctt tgactactgg 120 ggccaggga 129 <210> 7776 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7776 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Ser Val Trp Gln Trp 20 25 30 Leu Val Leu Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7777 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7777 Cys Ala Arg Ala Ser Pro Gly Ala Trp Gly Asp Trp Phe Asp Pro Trp 1 5 10 15 <210> 7778 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7778 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcacg cgcatcccct ggggcgtggg gggactggtt cgacccctgg 120 ggccaggga 129 <210> 7779 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7779 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ala Ser Pro Gly Ala 20 25 30 Trp Gly Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7780 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7780 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcacg cgcatcccct ggggcgtggg gggactggtt cgacccctgg 120 ggccaggga 129 <210> 7781 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7781 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ala Ser Pro Gly Ala 20 25 30 Trp Gly Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7782 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7782 Cys Ala His Arg Leu Phe Gly Ser Ser Trp Gly Glu Trp 1 5 10 <210> 7783 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7783 caccatcacc aaggacacct ccaaaaccag gtgatcctta cagtgaccaa catggaccct 60 gtggacacag ccacatatta ctgtgcacac agactttttg gcagcagctg gggggagtgg 120 ggccaggga 129 <210> 7784 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7784 His His His Gln Gly His Leu Gln Asn Gln Val Ile Leu Thr Val Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Leu 20 25 30 Phe Gly Ser Ser Trp Gly Glu Trp Gly Gln Gly 35 40 <210> 7785 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7785 accatcacca aggacacctc caaaaaccag gtgatcctta cagtgaccaa catggaccct 60 gtggacacag ccacatatta ctgtgcacac agactttttg gcagcagctg gggggagtgg 120 ggccaggga 129 <210> 7786 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7786 Thr Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Ile Leu Thr Val Thr 1 5 10 15 Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Leu 20 25 30 Phe Gly Ser Ser Trp Gly Glu Trp Gly Gln Gly 35 40 <210> 7787 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7787 Cys Ala Arg Arg Ala Gly Ala Gln Leu Val Arg His Asp Ser Tyr Tyr 1 5 10 15 Phe Asp Tyr Trp 20 <210> 7788 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7788 acgagcacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagac gggccggggc gcagctcgtc cgccacgact cttactactt tgactactgg 120 ggccaggga 129 <210> 7789 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7789 Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Arg Ala Gly Ala Gln Leu Val Arg His 20 25 30 Asp Ser Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7790 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7790 acgaccacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagac gggccggggc gcagctcgtc cgccacgact cttactactt tgactactgg 120 ggccaggga 129 <210> 7791 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7791 Thr Thr Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Arg Ala Gly Ala Gln Leu Val Arg His 20 25 30 Asp Ser Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7792 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7792 Cys Ala Ser Arg Arg Glu Asp Ile Val Val Val Val Ala Ala His Asp 1 5 10 15 Ala Phe Asp Ile Trp 20 <210> 7793 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7793 agcactgcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagccgcc gagaggatat tgtagtggtg gtagctgctc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7794 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7794 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Ser Arg Arg Glu Asp Ile Val Val Val Val Ala 20 25 30 Ala His Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7795 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7795 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagccgcc gagaggatat tgtagtggtg gtagctgctc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7796 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7796 Cys Ala Ile Arg Lys Leu Thr Gly Asp Thr Arg Asp Ala Phe Asp Ile 1 5 10 15 Trp <210> 7797 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7797 gacaggtcca agaaccagtt ctccctgaag ctgagctctg tgaccgccgc ggacacggcc 60 gtgtattact gtgccatacg aaagctaact ggggacaccc gtgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7798 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7798 Asp Arg Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala 1 5 10 15 Ala Asp Thr Ala Val Tyr Tyr Cys Ala Ile Arg Lys Leu Thr Gly Asp 20 25 30 Thr Arg Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7799 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7799 gacaggtcca agaaccagtt ctccctgaag ctgagccctg tgaccgccgc ggacacggcc 60 gtgtattact gtgccatacg aaagctaact ggggacaccc gtgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7800 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7800 Asp Arg Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Pro Val Thr Ala 1 5 10 15 Ala Asp Thr Ala Val Tyr Tyr Cys Ala Ile Arg Lys Leu Thr Gly Asp 20 25 30 Thr Arg Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7801 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7801 Cys Ala Lys Asp Ile Gly Tyr Ser Ser Ser Trp Ser Phe Asp Tyr Trp 1 5 10 15 <210> 7802 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7802 agagacaaca gcaaaaactc cctgtatctg caaatgaaca gtctgagaac tgaggacacc 60 gccttgtatt actgtgcaaa ggatatcggc tatagcagca gctggtcctt tgactactgg 120 ggccaggga 129 <210> 7803 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7803 Arg Asp Asn Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Thr Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Ile Gly Tyr Ser 20 25 30 Ser Ser Trp Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7804 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7804 agagacaaca gcaaaaactc cctgtatctg caaatgaaca gtctgagaac tgaggacacc 60 gccttgtatt actgtgcaaa agatatcggc tatagcagca gctggtcctt tgactactgg 120 ggccaggga 129 <210> 7805 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7805 Cys Ala Lys Gly Asp Ser Gly Ser Tyr Tyr Gly Ser Ser Tyr Phe Asp 1 5 10 15 Tyr Trp <210> 7806 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7806 aacgccaaga actccctgta tctgcaaatg aacagtctga gagctgagga cacggccttg 60 tattactgtg caaaagggga tagtgggagc tactacgggt cgtcctactt tgactactgg 120 ggccaggga 129 <210> 7807 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7807 Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Gly Asp Ser Gly Ser Tyr Tyr 20 25 30 Gly Ser Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7808 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7808 aacgccaaga actccctgta tctgcaaatg aacagtctga gagctgagga cacggccctg 60 tattactgtg caaaagggga tagtgggagc tactacgggt cgtcctactt tgactactgg 120 ggccaggga 129 <210> 7809 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7809 Cys Ala Arg Thr Ala Leu Gly Asp Gly Tyr Asn Thr Gly Trp Tyr Phe 1 5 10 15 Asp Leu Trp <210> 7810 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7810 tccaaaagcc aggtggtcct taccatgacc aacatggacc ctgtggacac agccacatat 60 tactgtgcac ggacagccct gggagatggc tacaatacgg gctggtactt cgatctctgg 120 ggccgtggc 129 <210> 7811 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7811 Ser Lys Ser Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala Arg Thr Ala Leu Gly Asp Gly Tyr Asn 20 25 30 Thr Gly Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 7812 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7812 ctccaaagcc aggtggtcct taccatgacc aacatggacc ctgtggacac agccacatat 60 tactgtgcac ggacagccct gggagatggc tacaatacgg gctggtactt cgatctctgg 120 ggccgtggc 129 <210> 7813 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7813 Leu Gln Ser Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala Arg Thr Ala Leu Gly Asp Gly Tyr Asn 20 25 30 Thr Gly Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 7814 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7814 Cys Ala Trp Asn Ser Asp Tyr Asp Leu Gly Gly Asp Tyr Trp 1 5 10 <210> 7815 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7815 attaccgcgg acaaatccac gagcacagcc tacatggaat tgagcagcct gagttctgag 60 gacacggccg tatattactg tgcgtggaat agtgactacg atttgggggg tgactactgg 120 ggccaggga 129 <210> 7816 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7816 Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Ser Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Trp Asn Ser Asp 20 25 30 Tyr Asp Leu Gly Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 7817 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7817 attaccgcgc acaaatccac gagcacagcc tacatggaat tgagcagcct gagttctgag 60 gacacggccg tatattactg tgcgtggaat agtgactacg atttgggggg tgactactgg 120 ggccaggga 129 <210> 7818 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7818 Ile Thr Ala His Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Ser Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Trp Asn Ser Asp 20 25 30 Tyr Asp Leu Gly Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 7819 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7819 Cys Ala His Ser Thr Tyr Ser Ser Ser Pro Gly Gly Met Asp Val Trp 1 5 10 15 <210> 7820 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7820 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagtacgtat agcagctcac ccggcggtat ggacgtctgg 120 ggccaaggg 129 <210> 7821 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7821 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Thr Tyr Ser Ser 20 25 30 Ser Pro Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7822 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7822 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagtacgtat agcagctcac ccggcggtat ggacgtctgg 120 ggccaaggg 129 <210> 7823 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7823 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Thr Tyr Ser Ser 20 25 30 Ser Pro Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7824 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7824 Cys Ala Lys Gly Gly Ser Leu Trp Phe Gly Asp His Pro Trp 1 5 10 <210> 7825 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7825 atctccatag ataattccaa gaacacgctt tatctgcata tgaacagtct gagagccgac 60 gacacggccg tatattactg tgcgaaaggg ggctcactct ggttcgggga ccacccctgg 120 ggccaggga 129 <210> 7826 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7826 Ile Ser Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu His Met Asn Ser 1 5 10 15 Leu Arg Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Ser 20 25 30 Leu Trp Phe Gly Asp His Pro Trp Gly Gln Gly 35 40 <210> 7827 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7827 atctccagag ataattccaa gaacacgctt tatctgcata tgaacagtct gagagccgac 60 gacacggccg tatattactg tgcgaaaggg ggctcactct ggttcgggga ccacccctgg 120 ggccaggga 129 <210> 7828 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7828 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu His Met Asn Ser 1 5 10 15 Leu Arg Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Ser 20 25 30 Leu Trp Phe Gly Asp His Pro Trp Gly Gln Gly 35 40 <210> 7829 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7829 Cys Ala Arg Gly Phe Ile Ala Ala Ala Trp Arg Gly Gly Phe Asp Tyr 1 5 10 15 Trp <210> 7830 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7830 gacaatgcca agaactcact gtatctgcaa atgaacagcc tgagagacga ggacacggct 60 gtgtattact gtgcgagagg ctttatagca gcagcttgga gggggggctt tgactactgg 120 ggccaggga 129 <210> 7831 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7831 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Phe Ile Ala Ala Ala 20 25 30 Trp Arg Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7832 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7832 gacaatgcca acaactcact gtatctgcaa atgaacagcc tgagagacga ggacacggct 60 gtgtattact gtgcgagagg ctttatagca gcagcttgga gggggggctt tgactactgg 120 ggccaggga 129 <210> 7833 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7833 Asp Asn Ala Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Phe Ile Ala Ala Ala 20 25 30 Trp Arg Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7834 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7834 Cys Val Arg Ala Ala Gly Tyr Ser Ser Gly Trp Ile Asp Tyr Trp 1 5 10 15 <210> 7835 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7835 aaccccgaca catccaagaa ccaattctcc ctgcagctga actctgtgac tcccgaggac 60 acggctgttt attactgtgt aagagccgcc gggtatagca gtggctggat tgactactgg 120 ggccgggga 129 <210> 7836 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7836 Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser Val 1 5 10 15 Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Ala Ala Gly Tyr 20 25 30 Ser Ser Gly Trp Ile Asp Tyr Trp Gly Arg Gly 35 40 <210> 7837 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7837 aaccccgaca catccaagaa ccaattctcc ctgcagctga actctgtgac tcccgaggac 60 acggctgttt attactgtgt aagagccgcc gggtatagca gtggctggat tgactactgg 120 ggccaggga 129 <210> 7838 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7838 Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser Val 1 5 10 15 Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Ala Ala Gly Tyr 20 25 30 Ser Ser Gly Trp Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 7839 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7839 Cys Ala Arg Gly Pro Leu Arg Glu Ser Ala Ala Gly Thr Val Asp Tyr 1 5 10 15 Tyr Tyr Gly Met Asp Val Trp 20 <210> 7840 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7840 gcctacttgg agctgagcag cctgagatct gaggacacgg ccgtgtatta ctgtgcgaga 60 ggcccgttgc gagagtcagc agctggtacg gtagactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7841 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7841 Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Gly Pro Leu Arg Glu Ser Ala Ala Gly Thr Val Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7842 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7842 gcctacatgg agctgagcag cctgagatct gaggacacgg ccgtgtatta ctgtgcgaga 60 ggcccgttgc gagagtcagc agctggtacg gtagactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7843 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7843 Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Gly Pro Leu Arg Glu Ser Ala Ala Gly Thr Val Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7844 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7844 Cys Val Arg Arg Ala Asn Asn Gly Ile Gly Ser Gln His Phe Phe Asp 1 5 10 15 Tyr Trp <210> 7845 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7845 acgtccgtca acacagccta catggggctg agcaggctga gatctgacga cacggccgtg 60 tattattgtg tgaggcgagc aaacaacggt atagggagtc agcacttctt tgactactgg 120 ggccaggga 129 <210> 7846 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7846 Thr Ser Val Asn Thr Ala Tyr Met Gly Leu Ser Arg Leu Arg Ser Asp 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Val Arg Arg Ala Asn Asn Gly Ile Gly 20 25 30 Ser Gln His Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7847 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7847 acgtccgtca acacagccta catggagctg agcaggctga gatctgacga cacggccgtg 60 tattattgtg tgaggcgagc aaacaacggt atagggagtc agcacttctt tgactactgg 120 ggccaggga 129 <210> 7848 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7848 Thr Ser Val Asn Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg Ser Asp 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Val Arg Arg Ala Asn Asn Gly Ile Gly 20 25 30 Ser Gln His Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7849 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7849 Cys Ala Ser Asp Pro Asp Tyr Gly Gly Lys Ser Tyr Phe Asp Asn Trp 1 5 10 15 <210> 7850 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7850 agagacaacg ccaagaatac gctctttctg caaatgaaca gtctgagagc cgaggacacg 60 tctgtgtatt attgtgcaag cgatcccgac tacggtggta agagctactt tgacaactgg 120 ggccaggga 129 <210> 7851 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7851 Arg Asp Asn Ala Lys Asn Thr Leu Phe Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ser Val Tyr Tyr Cys Ala Ser Asp Pro Asp Tyr Gly 20 25 30 Gly Lys Ser Tyr Phe Asp Asn Trp Gly Gln Gly 35 40 <210> 7852 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7852 agagacaacg ccaagaatac gccctttctg caaatgaaca gtctgagagc cgaggacacg 60 tctgtgtatt attgtgcaag cgatcccgac tacggtggta agagctactt tgacaactgg 120 ggccaggga 129 <210> 7853 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7853 Arg Asp Asn Ala Lys Asn Thr Pro Phe Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ser Val Tyr Tyr Cys Ala Ser Asp Pro Asp Tyr Gly 20 25 30 Gly Lys Ser Tyr Phe Asp Asn Trp Gly Gln Gly 35 40 <210> 7854 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7854 Cys Ala Arg Ala Ser Ala Arg Pro Gly Val Ala Thr Asn Leu Asp Phe 1 5 10 15 Trp <210> 7855 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7855 gacacctctg tcagcacgac atatctgcat atcagcagcc taaaggctga ggacactgcc 60 gtatattact gtgcgagagc gtctgcgcgt ccgggtgttg caacaaactt agacttctgg 120 ggccaggga 129 <210> 7856 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7856 Asp Thr Ser Val Ser Thr Thr Tyr Leu His Ile Ser Ser Leu Lys Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Ser Ala Arg Pro Gly 20 25 30 Val Ala Thr Asn Leu Asp Phe Trp Gly Gln Gly 35 40 <210> 7857 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7857 gacacctctg tcagcacgac atatctgcac atcagcagcc taaaggctga ggacactgcc 60 gtatattact gtgcgagagc gtctgcgcgt ccgggtgttg caacaaactt agacttctgg 120 ggccaggga 129 <210> 7858 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7858 Cys Glu Cys Lys Leu Arg Phe Leu Pro Phe Arg Val Tyr Trp 1 5 10 <210> 7859 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7859 aatctcaagc aacacccttt aagtgcagtc tgccttacaa tgaccaatct gaaagccaag 60 gacaaggtca tgtattactg tgagtgcaaa ttacgatttt taccattccg tgtctactgg 120 ggccaggga 129 <210> 7860 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7860 Asn Leu Lys Gln His Pro Leu Ser Ala Val Cys Leu Thr Met Thr Asn 1 5 10 15 Leu Lys Ala Lys Asp Lys Val Met Tyr Tyr Cys Glu Cys Lys Leu Arg 20 25 30 Phe Leu Pro Phe Arg Val Tyr Trp Gly Gln Gly 35 40 <210> 7861 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7861 atctcaagca acaccctttt aagtgcagtc tgccttacaa tgaccaatct gaaagccaag 60 gacaaggtca tgtattactg tgagtgcaaa ttacgatttt taccattccg tgtctactgg 120 ggccaggga 129 <210> 7862 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7862 Ile Ser Ser Asn Thr Leu Leu Ser Ala Val Cys Leu Thr Met Thr Asn 1 5 10 15 Leu Lys Ala Lys Asp Lys Val Met Tyr Tyr Cys Glu Cys Lys Leu Arg 20 25 30 Phe Leu Pro Phe Arg Val Tyr Trp Gly Gln Gly 35 40 <210> 7863 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7863 Cys Ala Arg Gly Met Val Arg Gly Ala Asn Arg Asp Val Trp 1 5 10 <210> 7864 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7864 atgaccagga acacctccat aagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagaggt atggttcggg gagctaatag ggacgtctgg 120 ggccaaggg 129 <210> 7865 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7865 Met Thr Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Met Val 20 25 30 Arg Gly Ala Asn Arg Asp Val Trp Gly Gln Gly 35 40 <210> 7866 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7866 atgaccagca acacctccat aagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagaggt atggttcggg gagctaatag ggacgtctgg 120 ggccaaggg 129 <210> 7867 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7867 Met Thr Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Met Val 20 25 30 Arg Gly Ala Asn Arg Asp Val Trp Gly Gln Gly 35 40 <210> 7868 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7868 Cys Ala Thr Asn Arg Leu Arg Asp Trp Ser Ser Asp Tyr Trp 1 5 10 <210> 7869 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7869 tactccagag ataattccga gaacacggtg tctctgcaaa tgaacagcct gagagccgag 60 gacacggccg tttattactg tgcgacaaat aggctgagag attggtcatc tgactactgg 120 ggccaggga 129 <210> 7870 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7870 Tyr Ser Arg Asp Asn Ser Glu Asn Thr Val Ser Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Asn Arg Leu 20 25 30 Arg Asp Trp Ser Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 7871 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7871 acctccagag ataattccga gaacacggtg tctctgcaaa tgaacagcct gagagccgag 60 gacacggccg tttattactg tgcgacaaat aggctgagag attggtcatc tgactactgg 120 ggccaggga 129 <210> 7872 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7872 Thr Ser Arg Asp Asn Ser Glu Asn Thr Val Ser Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Asn Arg Leu 20 25 30 Arg Asp Trp Ser Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 7873 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7873 Cys Ala Thr Ala Arg Ile Tyr Glu Pro Tyr Tyr Tyr Tyr Gly Met Asp 1 5 10 15 Val Trp <210> 7874 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7874 acatctacag acacagccta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg caacagcaag gatctatgaa ccctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7875 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7875 Thr Ser Thr Asp Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Thr Ala Arg Ile Tyr Glu Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7876 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7876 aaatctacag acacagccta catggagctg agcagcctga gatctgagga cacggccgtg 60 tattactgtg caacagcaag gatctatgaa ccctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7877 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7877 Lys Ser Thr Asp Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Thr Ala Arg Ile Tyr Glu Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7878 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7878 Cys Ala Arg Asp His Val Ser Gly Tyr Ser Ser Gly Trp Tyr Gly Cys 1 5 10 15 Gly Ile Ala Tyr Trp 20 <210> 7879 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7879 aacacgctgt atctgcaaat gaacagtctg agagccgagg acacggctgt gtattactgt 60 gcaagagacc acgtttccgg gtatagcagt ggctggtatg ggtgtgggat agcctactgg 120 ggccaggga 129 <210> 7880 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7880 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp His Val Ser Gly Tyr Ser Ser Gly Trp 20 25 30 Tyr Gly Cys Gly Ile Ala Tyr Trp Gly Gln Gly 35 40 <210> 7881 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7881 gaacacgctg tatctgcaat gaacagtctg agagccgagg acacggctgt gtattactgt 60 gcaagagacc acgtttccgg gtatagcagt ggctggtatg ggtgtgggat agcctactgg 120 ggccaggga 129 <210> 7882 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7882 Glu His Ala Val Ser Ala Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp His Val Ser Gly Tyr Ser Ser Gly Trp 20 25 30 Tyr Gly Cys Gly Ile Ala Tyr Trp Gly Gln Gly 35 40 <210> 7883 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7883 Cys Ala Arg Ala Pro Gly Ile Ala Ala Ala Gly Val Asp Trp 1 5 10 <210> 7884 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7884 atctccaggg acaacgccaa gaactcactg tatctgcaaa tgtacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagcc ccgggtatag cggcagccgg ggtagactgg 120 ggccaggga 129 <210> 7885 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7885 Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Tyr Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Pro Gly 20 25 30 Ile Ala Ala Ala Gly Val Asp Trp Gly Gln Gly 35 40 <210> 7886 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7886 atctccaggg acaacgccaa gaactcactg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagcc ccgggtatag cagcagccgg ggtagactgg 120 ggccaggga 129 <210> 7887 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7887 Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Pro Gly 20 25 30 Ile Ala Ala Ala Gly Val Asp Trp Gly Gln Gly 35 40 <210> 7888 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7888 Cys Ala Arg Gly Gly Ile Val Gly Ala Thr Ile Gly Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 7889 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7889 aaccagttct ccctgaagct gagctctgtg accgccgcgg acacggctgt gtattactgt 60 gcgagaggcg ggatagtggg agctactatc ggatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7890 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7890 Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Gly Ile Val Gly Ala Thr Ile Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7891 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7891 aaccagtcct ccctgaagct gagctctgtg gccgccgcgg acacggctgt gtattactgt 60 gcgagaggcg ggatagtggg agctactatc ggatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7892 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7892 Asn Gln Ser Ser Leu Lys Leu Ser Ser Val Ala Ala Ala Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Gly Ile Val Gly Ala Thr Ile Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7893 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7893 Cys Ala Arg Arg Gly Asp Asn Ser Gly Asn Tyr Tyr Val Ser Gly Trp 1 5 10 15 Phe Asp Pro Trp 20 <210> 7894 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7894 aaggaccact tctccctgaa gctgagctct gtgaccgccg cagacacggc tgtttattac 60 tgtgcgagac gaggtgacaa tagtggtaat tactatgtct ccgggtggtt cgacccctgg 120 ggccaggga 129 <210> 7895 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7895 Lys Asp His Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Arg Gly Asp Asn Ser Gly Asn Tyr Tyr 20 25 30 Val Ser Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7896 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7896 aagaaccact tctccctgaa gctgagctct gtgaccgccg cagacacggc tgtttattac 60 tgtgcgagac gaggtgacaa tagtggtaat tactatgtct ccgggtggtt cgacccctgg 120 ggccaggga 129 <210> 7897 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7897 Lys Asn His Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Arg Gly Asp Asn Ser Gly Asn Tyr Tyr 20 25 30 Val Ser Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7898 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7898 Cys Ala Thr His Ser Asp Gly Trp Tyr Gly Lys Gly Tyr Phe Asp Tyr 1 5 10 15 Trp <210> 7899 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7899 cacaactcca agaacacgtt gtatcttcaa atgaatagcc tgagaggcga ggacacggcc 60 gtgtattact gcgcgaccca tagtgatggc tggtacggga agggctactt tgactattgg 120 ggccagggc 129 <210> 7900 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7900 His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Gly 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr His Ser Asp Gly Trp Tyr 20 25 30 Gly Lys Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7901 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7901 gacaactcca agaacacgtt gtatcttcaa atgaatagcc tgagaggcga ggacacggcc 60 gtgtattact gcgcgaccca tagtgatggc tggtacggga agggctactt tgactattgg 120 ggccagggc 129 <210> 7902 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7902 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Gly 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr His Ser Asp Gly Trp Tyr 20 25 30 Gly Lys Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7903 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7903 Cys Ala Lys Gly Gly Gly Tyr Ser Ser Gly Tyr Tyr Tyr Phe Asp Tyr 1 5 10 15 Trp <210> 7904 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7904 gataattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaagg ggggggttat agtagtggtt actactactt tgactactgg 120 ggccaggga 129 <210> 7905 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7905 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Gly Tyr Ser Ser 20 25 30 Gly Tyr Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7906 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7906 gataattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaagg ggggggttat agtagtggtt actactactt tgactactgg 120 ggccaggga 129 <210> 7907 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7907 Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Gly Tyr Ser Ser 20 25 30 Gly Tyr Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7908 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7908 Cys Ala Ser Ser Leu Asp Gly Thr Gly Asp Phe Asp Tyr Trp 1 5 10 <210> 7909 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7909 atgaccagga acacctccat aagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagctct ctggacggaa cgggagactt tgactactgg 120 ggccaggga 129 <210> 7910 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7910 Met Thr Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Ser Leu Asp 20 25 30 Gly Thr Gly Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7911 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7911 atgaccagca acacctccat aagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagctct ctggacggaa cgggagactt tgactactgg 120 ggccaggga 129 <210> 7912 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7912 Met Thr Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Ser Leu Asp 20 25 30 Gly Thr Gly Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7913 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7913 Cys Ala Arg Asp Tyr Gly Asp Tyr Pro Gly Asp Trp 1 5 10 <210> 7914 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7914 gtcaccatga ccagggacac gtccatcagc acagcctaca tggagctgag caggctgaga 60 tctgacgaca cggccgtgta ttactgtgcg agagactacg gtgactaccc aggggactgg 120 ggccaggga 129 <210> 7915 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7915 Val Thr Met Thr Arg Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu 1 5 10 15 Ser Arg Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Tyr Gly Asp Tyr Pro Gly Asp Trp Gly Gln Gly 35 40 <210> 7916 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7916 ggcaccatga cctgggacac gtccatcagc acagcctaca tggagctgag caggctgaga 60 tctgacgaca cggccgtgta ttactgtgcg agagactacg gtgactaccc aggggactgg 120 ggccaggga 129 <210> 7917 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7917 Gly Thr Met Thr Trp Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu 1 5 10 15 Ser Arg Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Tyr Gly Asp Tyr Pro Gly Asp Trp Gly Gln Gly 35 40 <210> 7918 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7918 Cys Ala His Ser Ile Ile Ile Pro Val Ser His Trp Phe Asp Pro Trp 1 5 10 15 <210> 7919 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7919 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagtataata ataccggttt cacactggtt cgacccctgg 120 ggccaggga 129 <210> 7920 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7920 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Ile Ile Ile Pro 20 25 30 Val Ser His Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7921 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7921 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagtataata ataccggttt cacactggtt cgacccctgg 120 ggccaggga 129 <210> 7922 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7922 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Ile Ile Ile Pro 20 25 30 Val Ser His Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7923 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7923 Cys Ala Ser Ala His Ser Gly Tyr Glu Asp Pro Arg His Ala Phe Asp 1 5 10 15 Ile Trp <210> 7924 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7924 acatccacga gcacagccta catggagctg aggagcctga gatctgacga cacggccgtg 60 tattactgtg cgagcgctca tagtggctac gaagacccta gacatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7925 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7925 Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Ser Ala His Ser Gly Tyr Glu Asp 20 25 30 Pro Arg His Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7926 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7926 acatccacga gcacagccta catggagcgg aggagcctga gatctgacga cacggccgtg 60 tattactgtg cgagcgctca tagtggctac gaagacccta gacatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7927 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7927 Thr Ser Thr Ser Thr Ala Tyr Met Glu Arg Arg Ser Leu Arg Ser Asp 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Ser Ala His Ser Gly Tyr Glu Asp 20 25 30 Pro Arg His Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7928 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7928 Cys Ala Lys Asp Met Gly Ser Gly Ser Tyr Asp Ala Phe Asp Ile Trp 1 5 10 15 <210> 7929 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7929 atatataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatatgggt tcggggagtt atgacgcttt tgatatctgg 120 ggccaaggg 129 <210> 7930 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7930 Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Met Gly Ser Gly 20 25 30 Ser Tyr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7931 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7931 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatatgggt tcggggagtt atgacgcttt tgatatctgg 120 ggccaaggg 129 <210> 7932 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7932 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Met Gly Ser Gly 20 25 30 Ser Tyr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7933 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7933 Cys Thr Thr Asp Ala Asn Tyr Val Trp Trp Glu Leu Leu Gln Phe Asp 1 5 10 15 Tyr Trp <210> 7934 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7934 gattcaaaaa acacgctgta tctgcaaatg aacagcctga aaaccgagga cacagccgtg 60 tattactgta ccacagatgc caattacgtc tggtgggagc tactacagtt tgactactgg 120 ggccaggga 129 <210> 7935 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7935 Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Thr Thr Asp Ala Asn Tyr Val Trp Trp 20 25 30 Glu Leu Leu Gln Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7936 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7936 gattcaaaaa acacgctgta tctgcaaatg aacagcctga aaaccgagga cacagccgtg 60 tactactgta ccacagatgc caattacgtc tggtgggagc tactgcagtt tgactactgg 120 ggccaggga 129 <210> 7937 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7937 Cys Ala Arg Arg Leu Glu Tyr Ser Ser Ser Trp Gln Tyr Asn Trp Phe 1 5 10 15 Asp Pro Trp <210> 7938 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7938 tccatcagca ccgcctacct gcagtggagc agcctgaagg cctcggacac cgccatgtat 60 tactgtgcga gacgcctcga gtatagcagc agctggcagt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 7939 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7939 Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser Asp 1 5 10 15 Thr Ala Met Tyr Tyr Cys Ala Arg Arg Leu Glu Tyr Ser Ser Ser Trp 20 25 30 Gln Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7940 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7940 tccatcggca ccgcctacct gcagtggagc agcctgaagg cctcggacac cgccatgtat 60 tactgtgcga gacgcctcga gtatagcagc agctggcagt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 7941 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7941 Ser Ile Gly Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser Asp 1 5 10 15 Thr Ala Met Tyr Tyr Cys Ala Arg Arg Leu Glu Tyr Ser Ser Ser Trp 20 25 30 Gln Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7942 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7942 Cys Ala Arg Asp His Asp Asp Tyr Gly Leu Gly Gly Val Gly Tyr Trp 1 5 10 15 <210> 7943 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7943 tgggacacct ccatcaccac tgcctacatg gagttgagca ggctgaaatc tgacgacacg 60 gccgtgtatt actgtgcgag agaccacgat gactacggac tcgggggcgt gggctattgg 120 ggccagggc 129 <210> 7944 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7944 Trp Asp Thr Ser Ile Thr Thr Ala Tyr Met Glu Leu Ser Arg Leu Lys 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp His Asp Asp Tyr 20 25 30 Gly Leu Gly Gly Val Gly Tyr Trp Gly Gln Gly 35 40 <210> 7945 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7945 agggacacct ccatcaccac agcctacatg gagttgagca ggctgaaatc tgacgacacg 60 gccgtgtatt actgtgcgag agaccacgat gactacggac tcgggggcgt gggctattgg 120 ggccagggc 129 <210> 7946 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7946 Arg Asp Thr Ser Ile Thr Thr Ala Tyr Met Glu Leu Ser Arg Leu Lys 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp His Asp Asp Tyr 20 25 30 Gly Leu Gly Gly Val Gly Tyr Trp Gly Gln Gly 35 40 <210> 7947 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7947 Cys Ala Arg Asp Gly Glu Tyr Tyr Tyr Gly Ser Gly Ser Tyr Tyr Thr 1 5 10 15 Asp Ala Phe Asp Ile Trp 20 <210> 7948 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7948 acagcctact tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agagatgggg agtattacta tggttcaggg agttattata ctgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7949 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7949 Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Gly Glu Tyr Tyr Tyr Gly Ser Gly Ser Tyr 20 25 30 Tyr Thr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7950 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7950 acagcctaca tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agagatgggg agtattacta tggttcaggg agttattata ctgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 7951 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7951 Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Gly Glu Tyr Tyr Tyr Gly Ser Gly Ser Tyr 20 25 30 Tyr Thr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7952 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7952 Cys Ala Lys Glu Val Arg Leu Arg Pro Tyr Asn Trp Phe Asp Pro Trp 1 5 10 15 <210> 7953 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7953 ttagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agaggtccga ctccgacctt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 7954 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7954 Leu Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Val Arg Leu Arg 20 25 30 Pro Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7955 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7955 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agaggtccga ctccgacctt acaactggtt cgacccctgg 120 ggccaggga 129 <210> 7956 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7956 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Glu Val Arg Leu Arg 20 25 30 Pro Tyr Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7957 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7957 Cys Ala Arg Glu Phe Phe Asp Ile Leu Thr Gly Tyr Tyr Leu Asp Tyr 1 5 10 15 Trp <210> 7958 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7958 gacacctcca aaagccaggt ggtccttacc atgaccaaca tggaccctgt ggacacagcc 60 acatatttct gtgcacggga gtttttcgat attttgactg gttattatct cgactactgg 120 ggccaggga 129 <210> 7959 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7959 Asp Thr Ser Lys Ser Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Phe Cys Ala Arg Glu Phe Phe Asp Ile Leu 20 25 30 Thr Gly Tyr Tyr Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 7960 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7960 gacacctcca aaagccaggc ggtccttacc atgaccaaca tggaccctgt ggacacagcc 60 acatatttct gtgcacggga gtttttcgat attttgactg gttattatct cgactactgg 120 ggccgggga 129 <210> 7961 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7961 Asp Thr Ser Lys Ser Gln Ala Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Phe Cys Ala Arg Glu Phe Phe Asp Ile Leu 20 25 30 Thr Gly Tyr Tyr Leu Asp Tyr Trp Gly Arg Gly 35 40 <210> 7962 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7962 Cys Ala Lys Asp Ser Gly Asp Tyr Gly Gly Asp Pro Pro Phe Asp Tyr 1 5 10 15 Trp <210> 7963 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7963 tataattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga ttcgggggac tacggtggcg atcccccctt tgactactgg 120 ggccaggga 129 <210> 7964 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7964 Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Ser Gly Asp Tyr Gly 20 25 30 Gly Asp Pro Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7965 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7965 gataattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga ttcgggggac tacggtggcg atcccccctt tgactactgg 120 ggccaggga 129 <210> 7966 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7966 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Ser Gly Asp Tyr Gly 20 25 30 Gly Asp Pro Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7967 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7967 Cys Ala Arg Gly Asp Asp Thr Ser Ser Trp Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 7968 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7968 gtagacacgt ctatgaagct gttctccctg aagctgagct ctgtgactgc cgcggacacg 60 gccgtgtatt actgtgcgag aggggacgat accagcagct ggtactactt tgactactgg 120 ggccaggga 129 <210> 7969 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7969 Val Asp Thr Ser Met Lys Leu Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp Asp Thr Ser 20 25 30 Ser Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7970 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7970 gtagacacgt ctaagaagca gttctccctg aagctgagct ctgtgactgc cgcggacacg 60 gccgtgtatt actgtgcgag aggggacgat accagcagct ggtactactt tgactactgg 120 ggccaggga 129 <210> 7971 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7971 Val Asp Thr Ser Lys Lys Gln Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp Asp Thr Ser 20 25 30 Ser Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7972 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7972 Cys Ala Thr Ala Ser Arg Tyr Ser Pro Pro Gly Leu Leu Trp 1 5 10 <210> 7973 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7973 atgaccacag atctgtccac gagcacagcc tacatggaac tgaggaacct gagatcagac 60 gacacggcct tatattattg tgcgacggca tcgagatatt cgccacctgg gctcctctgg 120 ggccaggga 129 <210> 7974 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7974 Met Thr Thr Asp Leu Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Asn 1 5 10 15 Leu Arg Ser Asp Asp Thr Ala Leu Tyr Tyr Cys Ala Thr Ala Ser Arg 20 25 30 Tyr Ser Pro Pro Gly Leu Leu Trp Gly Gln Gly 35 40 <210> 7975 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7975 atgaccacag atctgcccac gagcacagcc tacatggaac tgaggaacct gagatcagac 60 gacacggcct tatattattg tgcgacggca tcgagatatt cgccacctgg gctcctctgg 120 ggccaggga 129 <210> 7976 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7976 Met Thr Thr Asp Leu Pro Thr Ser Thr Ala Tyr Met Glu Leu Arg Asn 1 5 10 15 Leu Arg Ser Asp Asp Thr Ala Leu Tyr Tyr Cys Ala Thr Ala Ser Arg 20 25 30 Tyr Ser Pro Pro Gly Leu Leu Trp Gly Gln Gly 35 40 <210> 7977 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7977 Cys Ala Arg Gly Arg Arg Tyr Phe Asp Tyr Trp 1 5 10 <210> 7978 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7978 cgagtcacca tatcagtaga cacgtccaag aaccagttct ccctgaagct gagctctgtg 60 accgccgcgg acacggctgt gtattactgt gcgagagggc gtcgatattt tgactactgg 120 ggccaggga 129 <210> 7979 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7979 Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys 1 5 10 15 Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg 20 25 30 Gly Arg Arg Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7980 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7980 cgagtcacca tatcagtaga cacgtccaag aaccagctct ccctgaagct gagctctgtg 60 accgccgcgg acacggctgc gtattactgt gcgagggggc gtcgatattt tgactactgg 120 ggccagggg 129 <210> 7981 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7981 Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Leu Ser Leu Lys 1 5 10 15 Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Ala Tyr Tyr Cys Ala Arg 20 25 30 Gly Arg Arg Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 7982 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7982 Cys Ala Arg Gly Ala Tyr Tyr Gly Ser Gly Ser Ser Ser Ser Pro Pro 1 5 10 15 Gln Asp Tyr Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 7983 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7983 tgcagcctga tatctgagga cacggccgtg tattactgtg cgcgaggggc ctactatggt 60 tcagggagtt cgtcgtcgcc accccaagat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7984 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7984 Cys Ser Leu Ile Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly 1 5 10 15 Ala Tyr Tyr Gly Ser Gly Ser Ser Ser Ser Pro Pro Gln Asp Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7985 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7985 agcagcctga gatctgagga cacggccgtg tattactgtg cgcgaggggc ctactatggt 60 tcagggagtt cgtcgtcgcc accccaagat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 7986 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7986 Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly 1 5 10 15 Ala Tyr Tyr Gly Ser Gly Ser Ser Ser Ser Pro Pro Gln Asp Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 7987 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7987 Cys Ala Lys Gly Leu Trp Phe Gly Gly Gly Gly Phe Asp Pro Trp 1 5 10 15 <210> 7988 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7988 tccagagata attccaagac cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggacta tggttcgggg ggggcgggtt cgacccctgg 120 ggccaggga 129 <210> 7989 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7989 Ser Arg Asp Asn Ser Lys Thr Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Trp Phe 20 25 30 Gly Gly Gly Gly Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7990 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7990 tccagagata attccaacaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaggacta tggttcgggg ggggcgggtt cgacccctgg 120 ggccaggga 129 <210> 7991 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7991 Ser Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Trp Phe 20 25 30 Gly Gly Gly Gly Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 7992 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7992 Cys Ala Lys Asp Arg Pro Val Arg Gly Glu Gly Ala Phe Asp Ile Trp 1 5 10 15 <210> 7993 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7993 atagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatcgtccg gttcgggggg aaggggcttt tgatatctgg 120 ggccaaggg 129 <210> 7994 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7994 Ile Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Pro Val Arg 20 25 30 Gly Glu Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7995 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7995 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatcgtccg gttcgggggg aaggggcttt tgatatctgg 120 ggccaaggg 129 <210> 7996 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7996 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Pro Val Arg 20 25 30 Gly Glu Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 7997 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7997 Cys Ala His Thr Glu Gly Val Tyr Gly Leu Asp Val Trp 1 5 10 <210> 7998 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7998 atcatcacca aggacacctc caaaaaccag gtggtcctga caatgaccaa catggcccct 60 gtggacacag ccacatatta ctgtgcacac acggaggggg tttacggttt ggacgtctgg 120 ggccaaggg 129 <210> 7999 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 7999 Ile Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Ala Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Thr Glu 20 25 30 Gly Val Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 8000 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8000 accatcacca aggacacctc caaaaaccag gtggtcctga caatgaccaa catggcccct 60 gtggacacag ccacatatta ctgtgcacac acggaggggg tttacggttt ggacgtctgg 120 ggccaaggg 129 <210> 8001 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8001 Thr Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr 1 5 10 15 Asn Met Ala Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Thr Glu 20 25 30 Gly Val Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 8002 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8002 Cys Ala Arg Arg Thr His Val Gln Gly Ser Asp Tyr Tyr Gly Met Asp 1 5 10 15 Val Trp <210> 8003 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8003 acgtccaaga accagttctc cctgaagctg agctctgtga ccgccgcaga cacggctgtg 60 tattactgtg cgagacgtac ccatgttcag ggatcggact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8004 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8004 Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Arg Thr His Val Gln Gly Ser 20 25 30 Asp Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8005 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8005 acgtccaaga accagttctc cctgaagctg agctctgtga ccgccgcaga cacggctgtg 60 tattactgtg cgagacgcac ccatgttcag ggatcggact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8006 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8006 Cys Ala Arg Ala Ala Ile Trp Phe Gly Glu Leu Ser Tyr Phe Asp Tyr 1 5 10 15 Trp <210> 8007 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8007 gacaattcca agaacacgct gtatcttcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgcgagagc cgctatatgg ttcggggagt tatcttactt tgactactgg 120 ggccaggga 129 <210> 8008 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8008 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Ala Ile Trp Phe Gly 20 25 30 Glu Leu Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8009 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8009 gacaattcca agaacacgct gtatcttcaa atgaacagcc cgagagccga ggacacggcc 60 gtgtattact gtgcgagagc cgctatatgg ttcggggagt tatcttactt tgactactgg 120 ggccaggga 129 <210> 8010 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8010 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Pro Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Ala Ile Trp Phe Gly 20 25 30 Glu Leu Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8011 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8011 Cys Thr Arg Gln Gly Asp Ser Ser Gly Trp Tyr Asp Gly Trp Phe Asp 1 5 10 15 Pro Trp <210> 8012 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8012 gattcaaaga acacggcgta tctgcaaatg aatagcctga aaaccgagga cacggccgtg 60 tattactgta ctagacaggg ggatagcagt ggctggtacg atggctggtt cgacccctgg 120 ggccaggga 129 <210> 8013 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8013 Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Thr Arg Gln Gly Asp Ser Ser Gly Trp 20 25 30 Tyr Asp Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8014 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8014 gattcaaaga acacggcgta tctgcaaatg aacagcctga aaaccgagga cacggccgtg 60 tattactgta ctagacaggg ggatagcagt ggctggtacg atggctggtt cgacccctgg 120 ggccaggga 129 <210> 8015 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8015 Cys Ala Arg Gly Glu Gly Tyr Ser Tyr Gly Ala Ser Gly Gly Pro Phe 1 5 10 15 Asp Tyr Trp <210> 8016 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8016 tccataagca cagcctacat ggagctgagc agcctgagat ttgaggacac ggccgtgtat 60 tactgtgcga gaggcgaggg atacagctat ggtgcctccg ggggcccctt tgactactgg 120 ggccaggga 129 <210> 8017 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8017 Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Phe Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Gly Glu Gly Tyr Ser Tyr Gly Ala 20 25 30 Ser Gly Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8018 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8018 tccataagca cagcctacat ggagctgagc agcctgagat ctgaggacac ggccgtgtat 60 tactgtgcga gaggcgaggg atacagctat ggtgcctccg ggggcccctt tgactactgg 120 ggccaggga 129 <210> 8019 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8019 Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Gly Glu Gly Tyr Ser Tyr Gly Ala 20 25 30 Ser Gly Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8020 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8020 Cys Ala Lys Asp His Tyr Gly Asp Tyr Pro Leu Leu Phe Asp Tyr Trp 1 5 10 15 <210> 8021 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8021 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatcactac ggtgactacc ctcttctctt tgactactgg 120 ggccaggga 129 <210> 8022 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8022 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp His Tyr Gly Asp 20 25 30 Tyr Pro Leu Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8023 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8023 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgcgcgaa agatcactac ggtgactacc ctcttctctt tgactactgg 120 ggccaggga 129 <210> 8024 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8024 Cys Ala Arg Asp Leu Arg Arg Ala Ala Phe Asp Ile Trp 1 5 10 <210> 8025 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8025 accatgacct gggacacgtc cacgagcaca gtctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga gatctacgcc gggctgcttt tgatatctgg 120 ggccaaggg 129 <210> 8026 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8026 Thr Met Thr Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu 20 25 30 Arg Arg Ala Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8027 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8027 accatgacca gggacacgtc cacgagcaca gtctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga gatctacgcc gggctgcttt tgatatctgg 120 ggccaaggg 129 <210> 8028 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8028 Thr Met Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu 20 25 30 Arg Arg Ala Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8029 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8029 Cys Ala Arg Thr Ser Arg Gly Ser Gly Tyr Tyr Tyr Tyr Trp 1 5 10 <210> 8030 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8030 attaccgcgg acaaatccac gagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagaacc tctcggggaa gtggttatta ctactactgg 120 ggccaggga 129 <210> 8031 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8031 Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Thr Ser Arg 20 25 30 Gly Ser Gly Tyr Tyr Tyr Tyr Trp Gly Gln Gly 35 40 <210> 8032 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8032 attaccgcgg acaaatccac gagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggcca tgtattactg tgcgagaacc tctcggggaa gtggttatta ctactactgg 120 ggccaggga 129 <210> 8033 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8033 Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Met Tyr Tyr Cys Ala Arg Thr Ser Arg 20 25 30 Gly Ser Gly Tyr Tyr Tyr Tyr Trp Gly Gln Gly 35 40 <210> 8034 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8034 Cys Ala Arg Gly Arg Gly Ser Gly Ser Tyr Leu Gly Tyr Trp 1 5 10 <210> 8035 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8035 ttatcagtag acacgcccaa gaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggctg tgtattactg tgcgagaggc aggggttcgg ggagttattt gggctactgg 120 ggccaggga 129 <210> 8036 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8036 Leu Ser Val Asp Thr Pro Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg Gly 20 25 30 Ser Gly Ser Tyr Leu Gly Tyr Trp Gly Gln Gly 35 40 <210> 8037 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8037 atatcagtag acacgtccaa gaaccagttc tccctgaagc tgagctctgt gaccgccgcg 60 gacacggctg tgtattactg tgcgagaggc aggggttcgg ggagttattt gggctactgg 120 ggccaggga 129 <210> 8038 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8038 Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser 1 5 10 15 Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg Gly 20 25 30 Ser Gly Ser Tyr Leu Gly Tyr Trp Gly Gln Gly 35 40 <210> 8039 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8039 Cys Ala His Arg Pro Gly Ile Val Gly Ala Ile Thr Glu Tyr Tyr Phe 1 5 10 15 Asp Tyr Trp <210> 8040 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8040 tccaaaaacc aggtggtcct tacaatgacc aacatggacc ctgtggacac agccacatat 60 tactgtgcac acagacccgg tatagtggga gctattaccg agtactactt tgactactgg 120 ggccaggga 129 <210> 8041 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8041 Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala His Arg Pro Gly Ile Val Gly Ala Ile 20 25 30 Thr Glu Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8042 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8042 ctccaaaacc aggtggtcct tacaatgacc aacatggacc ctgtggacac agccacatat 60 tactgtgcac acagacccgg tatagtggga gctattaccg agtactactt tgactactgg 120 ggccaggga 129 <210> 8043 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8043 Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala His Arg Pro Gly Ile Val Gly Ala Ile 20 25 30 Thr Glu Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8044 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8044 Cys Ala Arg Val Trp Asn Gly Pro Tyr Asp Ala Phe Asp Ile Trp 1 5 10 15 <210> 8045 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8045 accagggaca cgttcacgag cacagtctac atggagctga gcagcctgag atctgaggac 60 acggccgtgt attactgtgc gagagtttgg aacgggccct atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8046 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8046 Thr Arg Asp Thr Phe Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Trp Asn Gly 20 25 30 Pro Tyr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8047 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8047 accagggaca cgtccacgag cacagtctac atggagctga gcagcctgag atctgaggac 60 acggccgtgt attactgtgc gagagtttgg aacgggccct atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8048 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8048 Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Trp Asn Gly 20 25 30 Pro Tyr Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8049 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8049 Cys Ala Ser Phe Ser Gly Asp Gly Pro Phe Asp Tyr Trp 1 5 10 <210> 8050 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8050 accatctcca gagacaattc caagaacacg ctgtatcttc aaatgaacag cctgagggcc 60 gaggacacgg ccgtgtatta ctgtgcgagt tttagtgggg atggaccctt tgactactgg 120 ggccaggga 129 <210> 8051 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8051 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Phe Ser 20 25 30 Gly Asp Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8052 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8052 accatctcca gagacaattc caagaacacg ctgtatcttc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgagt tttagtgggg atggaccctt tgactactgg 120 ggccaggga 129 <210> 8053 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8053 Cys Ala Arg Lys Asp Thr Thr Val Thr Leu Met Ala Leu Asp Tyr Trp 1 5 10 15 <210> 8054 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8054 ttagacaatg ccaagaactc actgtatctg caaatgaaca gcctgagaga cgaggacacg 60 gctgtgtatt actgtgcgag gaaagacact acggtgaccc taatggccct tgactactgg 120 ggccaggga 129 <210> 8055 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8055 Leu Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Asp Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Lys Asp Thr Thr Val 20 25 30 Thr Leu Met Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8056 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8056 agagacaatg ccaagaactc actgtatctg caaatgaaca gcctgagaga cgaggacacg 60 gctgtgtatt actgtgcgag gaaagacact acggtgaccc taatggccct tgactactgg 120 ggccaggga 129 <210> 8057 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8057 Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Asp Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Lys Asp Thr Thr Val 20 25 30 Thr Leu Met Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8058 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8058 Cys Gly Arg Gly Arg Tyr Tyr Gly Met Asp Val Trp 1 5 10 <210> 8059 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8059 ttcaccatct ccagagacaa cgccaggaac accttatatc tgcaaatgaa cagtctgaga 60 gccgaggaca cggctgtata ttactgtgga agaggtagat actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8060 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8060 Phe Thr Ile Ser Arg Asp Asn Ala Arg Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Arg Gly 20 25 30 Arg Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8061 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8061 ttcaccatct ccagagacaa cgccaagaac atactgtttc tgcaaatgaa cagtctgaga 60 gccgaggaca cggctgtata ttactgtgga agaggtagat actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8062 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8062 Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ile Leu Phe Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Gly Arg Gly 20 25 30 Arg Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8063 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8063 Cys Ala Lys Phe Asn Gly Arg Ile Ala Ala Ala Thr Ile Asp Tyr Trp 1 5 10 15 <210> 8064 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8064 ttagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa attcaacggg cgtatagcag cagccacgat tgactactgg 120 ggccaggga 129 <210> 8065 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8065 Leu Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Phe Asn Gly Arg Ile 20 25 30 Ala Ala Ala Thr Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 8066 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8066 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa attcaacggg cgtatagcag cagccacgat tgactactgg 120 ggccaggga 129 <210> 8067 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8067 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Phe Asn Gly Arg Ile 20 25 30 Ala Ala Ala Thr Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 8068 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8068 Cys Ala Arg Gly Ala Gly Tyr Cys Ser Ser Thr Ser Cys His Phe Asp 1 5 10 15 Tyr Trp <210> 8069 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8069 gcgtctaaga accagttctc cctgaagctg agctctgtga ctgccgcgga catggccgtg 60 tattactgtg cgagaggagc gggatattgt agtagtacca gctgccactt tgactactgg 120 ggccaggga 129 <210> 8070 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8070 Ala Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Met Ala Val Tyr Tyr Cys Ala Arg Gly Ala Gly Tyr Cys Ser Ser 20 25 30 Thr Ser Cys His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8071 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8071 acgtctaaga accagttctc cctgaagctg agctctgtga ctgccgcgga cacggccgtg 60 tattactgtg cgagaggagc gggatattgt agtagtacca gctgccactt tgactactgg 120 ggccaggga 129 <210> 8072 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8072 Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Ala Gly Tyr Cys Ser Ser 20 25 30 Thr Ser Cys His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8073 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8073 Cys Ala Lys Asp Ser Trp Glu Thr Ser Ser Gly Trp Ser Gly Thr Phe 1 5 10 15 Asp Tyr Trp <210> 8074 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8074 tccaagaaca cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aagattcgtg ggagactagc agtggctggt caggaacgtt tgactactgg 120 ggccaggga 129 <210> 8075 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8075 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Asp Ser Trp Glu Thr Ser Ser Gly 20 25 30 Trp Ser Gly Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8076 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8076 tccaagaaca cgctgtacct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aagattcgtg ggagactagc agtggctggt caggaacgtt tgactactgg 120 ggccaggga 129 <210> 8077 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8077 Cys Ala Arg Glu Asp Gly Asp Ile Leu Thr Gly Tyr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 8078 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8078 atgaactcac tgtttctgca aatgaacagc ctgagagacg aggacacggc tgtgtattac 60 tgtgcgagag aggatgggga tattttgact ggttattact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8079 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8079 Met Asn Ser Leu Phe Leu Gln Met Asn Ser Leu Arg Asp Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Glu Asp Gly Asp Ile Leu Thr Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8080 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8080 aagaactcac tgtatctgca aatgaacagc ctgagagacg aggacacggc tgtgtattac 60 tgtgcgagag aggatgggga tattttgact ggttattact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8081 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8081 Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Glu Asp Gly Asp Ile Leu Thr Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8082 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8082 Cys Ala Arg Asp Ser Gly Val Ser Trp Tyr Tyr Tyr Tyr Gly Met Asp 1 5 10 15 Val Trp <210> 8083 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8083 acctctgtca gcatggcata tctgcagatc agcagcctaa aggctgagga cactgccgtg 60 tattactgtg cgagagattc gggagtttcg tggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8084 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8084 Thr Ser Val Ser Met Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ser Gly Val Ser Trp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8085 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8085 acctctgtca gcacggcata tctgcagatc agcagcctaa aggctgagga cactgccgtg 60 tattactgtg cgagagattc gggagtttcg tggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8086 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8086 Thr Ser Val Ser Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ser Gly Val Ser Trp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8087 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8087 Cys Ala Arg Glu Gly Thr Gly Asp Tyr Trp 1 5 10 <210> 8088 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8088 tgtcgagtca ccatatcagt agacacgtcc aagaaccagt tctccctgaa gctgagctct 60 gtgaccgccg cggacacggc cgtgtattac tgtgcgagag agggtacggg cgactactgg 120 ggccaggga 129 <210> 8089 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8089 Cys Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu 1 5 10 15 Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Arg Glu Gly Thr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 8090 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8090 agtcgagtca ccatatcagt agacacgtcc aagaaccagt tctccctgaa gctgagctct 60 gtgaccgccg cggacacggc cgtgtattac tgtgcgagag agggtacggg cgactactgg 120 ggccaggga 129 <210> 8091 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8091 Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu 1 5 10 15 Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Arg Glu Gly Thr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 8092 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8092 Cys Ala Arg Asp Arg Ser Gly Gly Leu Asp Tyr Trp 1 5 10 <210> 8093 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8093 gtcacgatta ccgcggacaa atccacgagc acagcctaca tggagctgag cagcctgaga 60 tctgaggaca cggccgtgta ttactgtgcg agagatcgga gcggggggct tgactactgg 120 ggccaggga 129 <210> 8094 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8094 Val Thr Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu 1 5 10 15 Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Arg Ser Gly Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8095 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8095 gtcacgatta ccgcgcacaa atccacgagc acagcctaca tggagctgag cagcctgaga 60 tctgaggaca cggccgtgta ttactgtgcg agagatcgga gcggggggct tgactactgg 120 ggccaggga 129 <210> 8096 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8096 Val Thr Ile Thr Ala His Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu 1 5 10 15 Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Arg Ser Gly Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8097 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8097 Cys Ala Arg Gly Arg Ala Ile Glu Arg Gly Tyr Ser Gly Tyr Tyr Tyr 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 8098 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8098 ctgaagctga gctctgtggc cgccgcggac acggctgtgt attactgtgc gagaggccgg 60 gcgattgaac gtggatatag tggctactat tattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8099 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8099 Leu Lys Leu Ser Ser Val Ala Ala Ala Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Arg Ala Ile Glu Arg Gly Tyr Ser Gly Tyr Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8100 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8100 ctgaagctga gctctgtgac cgccgcggac acggctgtgt attactgtgc gagaggccgg 60 gcgattgaac gtggatatag tggctactat tattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8101 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8101 Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Arg Ala Ile Glu Arg Gly Tyr Ser Gly Tyr Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8102 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8102 Cys Ala Arg Asp Pro Asn Pro Trp His Pro Asp Tyr Trp 1 5 10 <210> 8103 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8103 accatctcca gggacaacgc caagaactca ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gatccgaacc cgtggcaccc agactactgg 120 ggccaggga 129 <210> 8104 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8104 Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro 20 25 30 Asn Pro Trp His Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 8105 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8105 accatctcca gggacaacgc caacaactca ctgtatctgc aaatcaacag cctgagagcc 60 gaggacacgg ccgtgtatta ctgtgcgaga gatccgaacc cgtggcaccc agactactgg 120 ggccaggga 129 <210> 8106 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8106 Thr Ile Ser Arg Asp Asn Ala Asn Asn Ser Leu Tyr Leu Gln Ile Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro 20 25 30 Asn Pro Trp His Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 8107 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8107 Cys Ala Thr Gly Ser Ser Ile Ala Val Ala Gly Phe Phe Asp Tyr Trp 1 5 10 15 <210> 8108 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8108 tgggacacat ccgcgagcac tgcctacatg gagctgagca gcctgagatc tgaagacacg 60 gctgtgtatt actgtgcgac aggaagcagt atagcagtgg ctggtttttt tgactactgg 120 ggccaggga 129 <210> 8109 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8109 Trp Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Gly Ser Ser Ile Ala 20 25 30 Val Ala Gly Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8110 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8110 agggacacat ccgcgagcac agcctacatg gagctgagca gcctgagatc tgaagacacg 60 gctgtgtatt actgtgcgac aggaagcagt atagcagtgg ctggtttttt tgactactgg 120 ggccaggga 129 <210> 8111 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8111 Arg Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Thr Gly Ser Ser Ile Ala 20 25 30 Val Ala Gly Phe Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8112 <211> 26 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8112 Cys Ala Lys Asp Cys Ile Pro Ser Ile Val Gly Ala Thr Ile Val Gly 1 5 10 15 Tyr Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 8113 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8113 caaatgaaca gcctgagagc cgaggacacg gccgtatatt actgtgcgaa agattgtatc 60 cctagtatag tgggagctac tatcgtgggt tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8114 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8114 Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala 1 5 10 15 Lys Asp Cys Ile Pro Ser Ile Val Gly Ala Thr Ile Val Gly Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8115 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8115 aaaatgaact gcctgagagc cgaggacacg gccgtatatt actgtgcgaa agattgtatc 60 cctagtatag tgggagctac tatcgtgggt tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8116 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8116 Lys Met Asn Cys Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala 1 5 10 15 Lys Asp Cys Ile Pro Ser Ile Val Gly Ala Thr Ile Val Gly Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8117 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8117 Cys Thr Thr Asp Arg Ile Ala Val Ala Gly Met Gly Ser Gly Val Val 1 5 10 15 Asp Tyr Trp <210> 8118 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8118 tcaaaaaaca cgctgtatct gcaaatgaac agcctgaaaa ccgaggacac agccgtgtat 60 tactgtacca cagaccgtat agcagtggct ggtatggggt caggggtggt tgactactgg 120 ggccaggga 129 <210> 8119 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8119 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Thr Asp Arg Ile Ala Val Ala Gly Met 20 25 30 Gly Ser Gly Val Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 8120 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8120 ttcaaaaaca cgctgtatct gcaaatgaac agcctgaaaa ccgaggacac agccgtgtat 60 tactgtacca cagaccgtat agcagtggct ggtatggggt caggggtggt tgactactgg 120 ggccaggga 129 <210> 8121 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8121 Phe Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Thr Asp Arg Ile Ala Val Ala Gly Met 20 25 30 Gly Ser Gly Val Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 8122 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8122 Cys Ala Ser Ser Ser Ser Trp Gln Phe Asp Tyr Trp 1 5 10 <210> 8123 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8123 ttcaccatct ccagatataa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg agcagcagca gctggcaatt tgactactgg 120 ggccaggga 129 <210> 8124 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8124 Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Ser 20 25 30 Ser Ser Trp Gln Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8125 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8125 ttcaccatct ccagagataa ttccaagaac acgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg agcagcagca gctggcaatt tgactactgg 120 ggccaggga 129 <210> 8126 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8126 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Ser 20 25 30 Ser Ser Trp Gln Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8127 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8127 Cys Ala Arg Gly His Leu Leu Pro Pro Asp Tyr Asp Ile Leu Thr Gly 1 5 10 15 Tyr Phe Asp Tyr Trp 20 <210> 8128 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8128 aactcactgt atctgcaaat gaacagcctg agagacgagg atacggctgt gtattactgt 60 gcgagaggcc atttactccc acctgattac gatattttga ctggttattt tgactactgg 120 ggccaggga 129 <210> 8129 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8129 Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly His Leu Leu Pro Pro Asp Tyr Asp Ile 20 25 30 Leu Thr Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8130 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8130 aactcactgt atctgcaaat gaacagcctg agagacgagg acacggctgt gtattactgt 60 gcgagaggcc atttactccc acctgattac gatattttga ctggttattt tgactactgg 120 ggccaggga 129 <210> 8131 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8131 Cys Ala Arg Ala Asn Phe Met Gly Leu Glu Met Ala Arg Phe Asp Tyr 1 5 10 15 Trp <210> 8132 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8132 gacacattca cgagcacagc ctacatggag ctgaggagcc tgagatctga cgacacggcc 60 gtgtattact gtgcgagagc taattttatg gggctagaga tggctaggtt tgactactgg 120 ggccagggg 129 <210> 8133 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8133 Asp Thr Phe Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Asn Phe Met Gly Leu 20 25 30 Glu Met Ala Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8134 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8134 gacacatcca cgagcacagc ctacatggag ctgaggagcc tgagatctga cgacacggcc 60 gtgtattact gtgcgagagc taattttatg gggttagaga tggctaggtt tgactactgg 120 ggccaggga 129 <210> 8135 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8135 Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Asn Phe Met Gly Leu 20 25 30 Glu Met Ala Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8136 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8136 Cys Ala Arg Gln Ile Phe Tyr Gly Ser Gly Ser Tyr Tyr Ser Tyr Phe 1 5 10 15 Asp Tyr Trp <210> 8137 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8137 tccatcagca ccgcctacct gctgtggagc agcctgaagg cctcggacac cgccaggtat 60 tactgtgcga gacagatctt ctatggttcg gggagttatt actcatactt tgactactgg 120 ggccaggga 129 <210> 8138 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8138 Ser Ile Ser Thr Ala Tyr Leu Leu Trp Ser Ser Leu Lys Ala Ser Asp 1 5 10 15 Thr Ala Arg Tyr Tyr Cys Ala Arg Gln Ile Phe Tyr Gly Ser Gly Ser 20 25 30 Tyr Tyr Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8139 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8139 tccatcagca ccgcctacct gcagtggagc agcctgaagg cctcggacac cgccatgtat 60 tactgtgcga gacagatctt ctatggttcg gggagttatt actcatactt tgactactgg 120 ggccaggga 129 <210> 8140 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8140 Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser Asp 1 5 10 15 Thr Ala Met Tyr Tyr Cys Ala Arg Gln Ile Phe Tyr Gly Ser Gly Ser 20 25 30 Tyr Tyr Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8141 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8141 Cys Thr Arg His Tyr Asp Ile Leu Thr Gly Tyr Arg Phe Asp Leu Trp 1 5 10 15 <210> 8142 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8142 tgtgatgatt caaagaacac ggcgtatctg caaatgaaca gcctgaaaac cgaggacacg 60 gccgtgtatt actgtactag acattacgat attttgactg gttatcgctt cgatctctgg 120 ggccgtggc 129 <210> 8143 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8143 Cys Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys 1 5 10 15 Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg His Tyr Asp Ile Leu 20 25 30 Thr Gly Tyr Arg Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8144 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8144 agagatgatt caaagaacac ggcgtatctg caaatgaaca gcctgaaaac cgaggacacg 60 gccgtgtatt actgtactag acattacgat attttgactg gttatcgctt cgatctctgg 120 ggccgtggc 129 <210> 8145 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8145 Arg Asp Asp Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys 1 5 10 15 Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Arg His Tyr Asp Ile Leu 20 25 30 Thr Gly Tyr Arg Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8146 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8146 Cys Ala Lys Asp Ile Ser Lys Ile Lys Ser Trp Tyr Asp Leu Gly Gly 1 5 10 15 Gly Ala Phe Asp Leu Trp 20 <210> 8147 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8147 tccctgtatc tgcaaatgaa cagtctgaga gctgaggaca cggccttgta ttactgtgca 60 aaagatatct ctaagatcaa gagctggtac gatctaggtg gaggggcctt cgatctctgg 120 ggccgtggc 129 <210> 8148 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8148 Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Ile Ser Lys Ile Lys Ser Trp Tyr Asp Leu 20 25 30 Gly Gly Gly Ala Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8149 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8149 tacctgtatc tgcaaatgat cagtctgaga gctgaggaca cggccttgta ttactgtgca 60 aaagatatct ctaagatcaa gagctggtac gatctaggtg gaggggcctt cgatctctgg 120 ggccgtggc 129 <210> 8150 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8150 Tyr Leu Tyr Leu Gln Met Ile Ser Leu Arg Ala Glu Asp Thr Ala Leu 1 5 10 15 Tyr Tyr Cys Ala Lys Asp Ile Ser Lys Ile Lys Ser Trp Tyr Asp Leu 20 25 30 Gly Gly Gly Ala Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8151 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8151 Cys Ala Arg Asp Ile Gly Ser Thr Leu Pro Tyr Tyr Tyr Tyr Gly Met 1 5 10 15 Asp Val Trp <210> 8152 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8152 tccacgagca cagcctacat ggagctgagc agcctgagat ctgaggacac ggccgtgtat 60 tactgtgcga gagatatagg cagcacccta ccatactatt actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8153 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8153 Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ile Gly Ser Thr Leu Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8154 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8154 tccacgagca cagcctacat ggagctgagc agcctgagat ctgaggacac ggccgtgtat 60 tactgtgcga gagatatagg cagcacccta ccatactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8155 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8155 Cys Ala Lys Asp Ile Lys Gln Gln Leu Val Leu Asp Ala Phe Asp Ile 1 5 10 15 Trp <210> 8156 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8156 gacaacagca aaaactccct gtatctgcaa atgaacagtc tgagaactga ggacaccgcc 60 ttgtattact gtgcaaaaga tattaagcag cagctggtac tggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8157 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8157 Asp Asn Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Thr 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Ile Lys Gln Gln Leu 20 25 30 Val Leu Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8158 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8158 gacaacagca aaaactccct gtatctgcaa atgaacagtc tgagaactga ggacaccgcc 60 tcgtattact gtgcaaaaga tattaagcag cagctggtac tggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8159 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8159 Asp Asn Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Thr 1 5 10 15 Glu Asp Thr Ala Ser Tyr Tyr Cys Ala Lys Asp Ile Lys Gln Gln Leu 20 25 30 Val Leu Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8160 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8160 Cys Ala Lys Gln Gln Gln Leu Val Pro Lys Ser His Phe Asp Tyr Trp 1 5 10 15 <210> 8161 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8161 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa gcagcagcag ctggttccca aaagccattt tgactactgg 120 ggccaggga 129 <210> 8162 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8162 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gln Gln Gln Leu Val 20 25 30 Pro Lys Ser His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8163 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8163 agagacaatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa gcaacagcag ctggttccca aaagccattt tgactactgg 120 ggccaggga 129 <210> 8164 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8164 Cys Ser Arg Gly Gly Gly Pro Ala Ala Gly Phe His Gly Leu Asp Val 1 5 10 15 Trp <210> 8165 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8165 gacacatccg cgaacacagc ctgcatggaa ctgagtggcc tgagatctga agacacggct 60 gcgtatttct gttcgagggg agggggccca gcagctggtt tccacggttt ggacgtctgg 120 ggccaaggg 129 <210> 8166 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8166 Asp Thr Ser Ala Asn Thr Ala Cys Met Glu Leu Ser Gly Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Ala Tyr Phe Cys Ser Arg Gly Gly Gly Pro Ala Ala 20 25 30 Gly Phe His Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 8167 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8167 gacacatccg cgaacacagc ctacatggaa ctgagtggcc tgagatctga agacacggct 60 gtgtatttct gttcgagggg agggggccca gcagctggtt tccacggttt ggacgtctgg 120 ggccaaggg 129 <210> 8168 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8168 Asp Thr Ser Ala Asn Thr Ala Tyr Met Glu Leu Ser Gly Leu Arg Ser 1 5 10 15 Glu Asp Thr Ala Val Tyr Phe Cys Ser Arg Gly Gly Gly Pro Ala Ala 20 25 30 Gly Phe His Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 8169 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8169 Cys Ala Arg Gly Gly Tyr Cys Ser Ser Thr Ser Cys Tyr Gly Gly Asn 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 8170 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8170 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagaggggga 60 tattgtagta gtaccagctg ctatggcggg aactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8171 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8171 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Gly Tyr Cys Ser Ser Thr Ser Cys Tyr Gly Gly Asn Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8172 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8172 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagaggggga 60 tattgtagta gtaccagctg ctatggcggg aactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8173 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8173 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Gly Tyr Cys Ser Ser Thr Ser Cys Tyr Gly Gly Asn Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8174 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8174 Cys Ala Arg Gly Gly Pro Tyr Cys Gly Gly Asp Cys Tyr Val Asp Tyr 1 5 10 15 Trp <210> 8175 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8175 gacacgtcca tcagcacagc ctacatggaa ctgagcaggc tgagatctga cgacacggcc 60 gtatattact gtgcgagggg aggtccatat tgtggtggtg actgctacgt tgactactgg 120 ggccaggga 129 <210> 8176 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8176 Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg Ser 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Pro Tyr Cys Gly 20 25 30 Gly Asp Cys Tyr Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 8177 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8177 gacacgtcca tcagcacagc ctacatggaa ctgagcaggc tgagatctga cgacacggcc 60 gtatattact gtgcgagggg aggcccatat tgtggtggtg actgctacgt tgactactgg 120 ggccaggga 129 <210> 8178 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8178 Cys Ala Lys Asp Arg Arg Leu Asp Tyr Asp Asp Ser Gly Ser Phe Asp 1 5 10 15 Ser Trp <210> 8179 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8179 gattccgaga acacattgta tctgcacatg agtggcctgc gagccgaaga cacggccgta 60 tattactgtg cgaaagatcg gcgcctcgac tatgatgata gtggctcctt tgactcctgg 120 ggccaggga 129 <210> 8180 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8180 Asp Ser Glu Asn Thr Leu Tyr Leu His Met Ser Gly Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Arg Leu Asp Tyr Asp 20 25 30 Asp Ser Gly Ser Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 8181 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8181 gattccgaca acacattgta tctgcacatg aggggcctgc gagccgaaga cacggccgta 60 tattactgtg cgaaagatcg gcgcctcgac tatgatgata gtggctcctt tgactcctgg 120 ggccaggga 129 <210> 8182 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8182 Asp Ser Asp Asn Thr Leu Tyr Leu His Met Arg Gly Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Arg Leu Asp Tyr Asp 20 25 30 Asp Ser Gly Ser Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 8183 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8183 Cys Ala Arg Val His His Tyr Asp Phe Trp Ser Gly Tyr Tyr Tyr Pro 1 5 10 15 Tyr Tyr Tyr Gly Met Asp Val Trp 20 <210> 8184 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8184 atcttgaaaa tcaacagtct gagagccgag gacacggctg tgtattactg tgcaagagtc 60 caccattacg atttttggag tggttattat tatccctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8185 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8185 Ile Leu Lys Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Val His His Tyr Asp Phe Trp Ser Gly Tyr Tyr Tyr Pro 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8186 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8186 tatctgcaaa tgaacagtct gagagccgag gacacggctg tgtattactg tgcaagagtc 60 caccattacg atttttggag tggttattat tatccctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8187 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8187 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Arg Val His His Tyr Asp Phe Trp Ser Gly Tyr Tyr Tyr Pro 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8188 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8188 Cys Ala Lys Asp Phe Phe Pro Ser Gln Arg Ile Tyr Gly Ser Gly Ser 1 5 10 15 Cys Phe Asp Tyr Trp 20 <210> 8189 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8189 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatt ttttcccctc gcaacgaata tatggttcgg ggagttgctt tgactactgg 120 ggccaggga 129 <210> 8190 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8190 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Phe Phe Pro Ser Gln Arg Ile Tyr Gly 20 25 30 Ser Gly Ser Cys Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8191 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8191 aacacgctgt atccgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatt ttttcccctc gcaacgaata tatggttcgg ggagttgctt tgactactgg 120 ggccaggga 129 <210> 8192 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8192 Asn Thr Leu Tyr Pro Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Phe Phe Pro Ser Gln Arg Ile Tyr Gly 20 25 30 Ser Gly Ser Cys Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8193 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8193 Cys Thr Arg His Arg Asp His Ile Val Gly Val Gly Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 8194 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8194 aacacggcgt atctgcaaat gaacagcctg aaaaccgagg acacggccgt gtattactgt 60 actagacatc gcgatcatat tgtgggggtt gggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8195 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8195 Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Thr Arg His Arg Asp His Ile Val Gly Val Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8196 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8196 tacacggcgt atctgcaaat gaacagcctg aaaaccgagg acacggccgt gtattactgt 60 actagacatc gcgatcatat tgtgggggtt gggtactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8197 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8197 Tyr Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Thr Arg His Arg Asp His Ile Val Gly Val Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8198 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8198 Cys Ala Arg Gly Leu Ile Ala Ala Ala Gly Thr Ala Val Pro Asp Ala 1 5 10 15 Ser Met Asp Val Trp 20 <210> 8199 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8199 aactccttgt atcttcaaat gaacagcctg agagccgggg acacggctgt gtattactgt 60 gcaagagggc tcatagcagc agctggtacc gccgtccctg atgctagtat ggacgtctgg 120 ggccaaggg 129 <210> 8200 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8200 Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Gly Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Leu Ile Ala Ala Ala Gly Thr Ala Val 20 25 30 Pro Asp Ala Ser Met Asp Val Trp Gly Gln Gly 35 40 <210> 8201 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8201 gaactccttg tatcttcaat gaacagcctg agagccgggg acacggctgt gtattactgt 60 gcaagagggc tcatagcagc agctggtacc gccgtccctg atgctagtat ggacgtctgg 120 ggccaaggg 129 <210> 8202 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8202 Glu Leu Leu Val Ser Ser Met Asn Ser Leu Arg Ala Gly Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Leu Ile Ala Ala Ala Gly Thr Ala Val 20 25 30 Pro Asp Ala Ser Met Asp Val Trp Gly Gln Gly 35 40 <210> 8203 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8203 Cys Ala His Arg Leu Arg Tyr Ser Ser Gly Val Asp Tyr Trp 1 5 10 <210> 8204 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8204 catcaccaag gacacctcca aaaccaggtg gtccttacaa tgaccaacat ggaccctgtg 60 gacacagcca catattactg tgcacacaga ctaaggtata gcagtggcgt tgactactgg 120 ggccaggga 129 <210> 8205 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8205 His His Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Leu Arg 20 25 30 Tyr Ser Ser Gly Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 8206 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8206 atcaccaagg acacctccaa aaaccaggtg gtccttacaa tgaccaacat ggaccctgtg 60 gacacagcca catattactg tgcacacaga ctaaggtata gcagtggcgt tgactactgg 120 ggccaggga 129 <210> 8207 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8207 Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Leu Arg 20 25 30 Tyr Ser Ser Gly Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 8208 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8208 Cys Ala Lys Ala Trp Gly Tyr Ser Ser Gly Trp Tyr Gly Ser Trp Val 1 5 10 15 Ser Glu Asn Ala Phe Asp Ile Trp 20 <210> 8209 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8209 tatctgcaat tgaacagcct gagagccgag gacacggccg tatattactg tgcgaaagcg 60 tggggatata gcagtggctg gtacgggtcg tgggtcagtg aaaatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8210 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8210 Tyr Leu Gln Leu Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Ala Trp Gly Tyr Ser Ser Gly Trp Tyr Gly Ser Trp Val 20 25 30 Ser Glu Asn Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8211 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8211 tatctgcaaa tgaacagcct gagagccgag gacacggccg tatattactg tgcgaaagcg 60 tggggatata gcagtggctg gtacgggtcg tgggtcagtg aaaatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8212 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8212 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Ala Trp Gly Tyr Ser Ser Gly Trp Tyr Gly Ser Trp Val 20 25 30 Ser Glu Asn Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8213 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8213 Cys Ala Arg Gly Arg Trp Leu Asp Trp Phe Asp Pro Trp 1 5 10 <210> 8214 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8214 accatgacca cagacacatc cacgagcaca gcctacatgg agctgaggag cctgagatct 60 gacgacatgg ccgtgtatta ctgtgcgaga ggtcggtggc tggactggtt cgacccctgg 120 ggccaggga 129 <210> 8215 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8215 Thr Met Thr Thr Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg 1 5 10 15 Ser Leu Arg Ser Asp Asp Met Ala Val Tyr Tyr Cys Ala Arg Gly Arg 20 25 30 Trp Leu Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8216 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8216 accatgacca cagacacatc cacgagcaca gcctacatgg agctgaggag cctgagatct 60 gacgacacgg ccgtgtatta ctgtgcgaga ggtcggtggc tggactggtt cgacccctgg 120 ggccaggga 129 <210> 8217 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8217 Thr Met Thr Thr Asp Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg 1 5 10 15 Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg 20 25 30 Trp Leu Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8218 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8218 Cys Ala Lys Glu Glu Tyr Tyr Tyr Asp Ser Ser Gly Pro Asn Trp Phe 1 5 10 15 Asp Pro Trp <210> 8219 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8219 tccaagaaca cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aagaagagta ttactatgat agtagtggcc ccaactggtt cgacccctgg 120 ggccaggga 129 <210> 8220 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8220 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Glu Glu Tyr Tyr Tyr Asp Ser Ser 20 25 30 Gly Pro Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8221 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8221 tccaggaaca cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aagaagagta ttactatgat agtagtggcc ccaactggtt cgacccctgg 120 ggccaggga 129 <210> 8222 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8222 Ser Arg Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Glu Glu Tyr Tyr Tyr Asp Ser Ser 20 25 30 Gly Pro Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8223 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8223 Cys Ala Lys Gly Gly Gly Leu Phe Asp Tyr Trp 1 5 10 <210> 8224 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8224 cggttcacca tctccagata taattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaaggag gcggtctctt tgactactgg 120 ggccaggga 129 <210> 8225 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8225 Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Gly Gly Gly Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8226 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8226 cggttcacca tctccagaga taattccaag aacacgctgt atctgcaaat gaacagcctg 60 agagccgagg acacggccgt atattactgt gcgaaaggag gcggtctctt tgactactgg 120 ggccaggga 129 <210> 8227 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8227 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Gly Gly Gly Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8228 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8228 Cys Val Arg Ile Ala Ala Ala Val Asn Asp Ala Phe Asp Ile Trp 1 5 10 15 <210> 8229 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8229 tccagatata tttccaagaa caccctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attattgtgt gagaattgca gcagctgtta atgatgcttt tgatatctgg 120 ggccgaggg 129 <210> 8230 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8230 Ser Arg Tyr Ile Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Ile Ala Ala Ala 20 25 30 Val Asn Asp Ala Phe Asp Ile Trp Gly Arg Gly 35 40 <210> 8231 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8231 tccagagata tttccaagaa caccctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attattgtgt gagaattgca gcagctgtta atgatgcttt tgatatctgg 120 ggccgaggg 129 <210> 8232 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8232 Ser Arg Asp Ile Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Ile Ala Ala Ala 20 25 30 Val Asn Asp Ala Phe Asp Ile Trp Gly Arg Gly 35 40 <210> 8233 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8233 Cys Ala Arg Arg Ser Pro Tyr Ser Ser Ala Trp Tyr Phe Asp Leu Trp 1 5 10 15 <210> 8234 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8234 gccgacaagt ccatcagcac cgcctacctg cagtggagca gcctgaaggc ctcggacacc 60 gccatgtatt actgtgcgag acggtctccg tatagcagtg cctggtactt cgatctctgg 120 ggccgtggc 129 <210> 8235 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8235 Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys 1 5 10 15 Ala Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Arg Ser Pro Tyr Ser 20 25 30 Ser Ala Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8236 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8236 gccgacaagt ccatcagcac cacttacctg cagtggatca gcctgaaggc ctcggacacc 60 gccatctatt actgtgcgag acggtctccg tatagcagtg cctggtactt cgatctctgg 120 ggccgtggc 129 <210> 8237 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8237 Ala Asp Lys Ser Ile Ser Thr Thr Tyr Leu Gln Trp Ile Ser Leu Lys 1 5 10 15 Ala Ser Asp Thr Ala Ile Tyr Tyr Cys Ala Arg Arg Ser Pro Tyr Ser 20 25 30 Ser Ala Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8238 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8238 Cys Ala Lys Asp Leu Arg Gly Asp Glu Glu Asp Tyr Trp 1 5 10 <210> 8239 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8239 tacatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ctgtgtatta ctgtgcgaaa gatttaagag gggatgagga ggactactgg 120 ggccaggga 129 <210> 8240 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8240 Tyr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu 20 25 30 Arg Gly Asp Glu Glu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8241 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8241 accatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ctgtgtatta ctgtgcgaaa gatttaagag gggatgagga ggactactgg 120 ggccaggga 129 <210> 8242 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8242 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu 20 25 30 Arg Gly Asp Glu Glu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8243 <211> 29 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8243 Cys Ala Lys Ala Tyr Glu Ala Val Ala Thr Gly Trp Phe Tyr Tyr Tyr 1 5 10 15 Gly Ser Gly Ser Tyr Tyr Lys Glu Tyr Phe Gln His Trp 20 25 <210> 8244 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8244 tgcctgagag ccgaggacac ggccgtatat tactgtgcga aagcttacga ggccgtcgcc 60 accgggtggt tctattacta tggttcgggg agttattata aggaatactt ccagcactgg 120 ggccagggc 129 <210> 8245 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8245 Cys Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Tyr 1 5 10 15 Glu Ala Val Ala Thr Gly Trp Phe Tyr Tyr Tyr Gly Ser Gly Ser Tyr 20 25 30 Tyr Lys Glu Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 8246 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8246 agcctgagag ccgaggacac ggccgtatat tactgtgcga aagcttacga ggccgtcgcc 60 accgggtggt tctattacta tggttcgggg agttattata aggaatactt ccagcactgg 120 ggccagggc 129 <210> 8247 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8247 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Tyr 1 5 10 15 Glu Ala Val Ala Thr Gly Trp Phe Tyr Tyr Tyr Gly Ser Gly Ser Tyr 20 25 30 Tyr Lys Glu Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 8248 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8248 Cys Ala Leu Asn Leu Gly Tyr Cys Ser Gly Gly Ser Cys Tyr Ser Glu 1 5 10 15 Asn Tyr Leu Asp Tyr Trp 20 <210> 8249 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8249 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 ctaaacctag gatattgtag tggtggtagc tgctactcag aaaattatct tgactactgg 120 ggccaggga 129 <210> 8250 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8250 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Leu Asn Leu Gly Tyr Cys Ser Gly Gly Ser Cys Tyr 20 25 30 Ser Glu Asn Tyr Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8251 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8251 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 ctaaacctag gatattgtag tggtggtagc tgctactcag aaaattatct tgactactgg 120 ggccaggga 129 <210> 8252 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8252 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Leu Asn Leu Gly Tyr Cys Ser Gly Gly Ser Cys Tyr 20 25 30 Ser Glu Asn Tyr Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8253 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8253 Cys Ala His Ser Gly Lys Thr Arg Leu Gly Glu Leu Ser Pro Asp Tyr 1 5 10 15 Trp <210> 8254 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8254 gacacctcca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacag cgggaaaact cgtttggggg agttatcgcc tgactactgg 120 ggccaggga 129 <210> 8255 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8255 Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Gly Lys Thr Arg Leu 20 25 30 Gly Glu Leu Ser Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 8256 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8256 ggacacctcc aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacag cgggaaaact cgtttggggg agttatcgcc tgactactgg 120 ggccaggga 129 <210> 8257 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8257 Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Gly Lys Thr Arg Leu 20 25 30 Gly Glu Leu Ser Pro Asp Tyr Trp Gly Gln Gly 35 40 <210> 8258 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8258 Cys Ala Arg Glu Asn Ser Ile Thr Gly Thr Thr Pro Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 8259 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8259 tgcacagcct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagaga acagtataac tggaacgacg ccttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8260 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8260 Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Asn Ser Ile Thr Gly Thr Thr Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8261 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8261 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagaga acagtataac tggaacgacg ccttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8262 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8262 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Asn Ser Ile Thr Gly Thr Thr Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8263 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8263 Cys Ala Arg Asp Ile Gly Ser Gly Trp Glu Ile Tyr Val Asp Tyr Trp 1 5 10 15 <210> 8264 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8264 acagacaaat ccacgagcac agcctgcatg gagccgagga gcctgagatc tgacgacacg 60 gccgtttatt actgtgcgag agatattggc agtggctggg aaatttatgt tgactactgg 120 ggccaggga 129 <210> 8265 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8265 Thr Asp Lys Ser Thr Ser Thr Ala Cys Met Glu Pro Arg Ser Leu Arg 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ile Gly Ser Gly 20 25 30 Trp Glu Ile Tyr Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 8266 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8266 acagacaaat ccacgagcac agcctacatg gagctgagga gcctgagatc tgacgacacg 60 gccgtttatt actgtgcgag agatattggc agtggctggg aaatttatgt tgactactgg 120 ggccaggga 129 <210> 8267 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8267 Thr Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ile Gly Ser Gly 20 25 30 Trp Glu Ile Tyr Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 8268 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8268 Cys Ala Arg Asp Met Val Ala Ala Ala Gly Thr Pro Phe Asp Tyr Trp 1 5 10 15 <210> 8269 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8269 tgggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agatatggta gcagcagctg gtaccccctt tgactactgg 120 ggccaggga 129 <210> 8270 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8270 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Met Val Ala Ala 20 25 30 Ala Gly Thr Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8271 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8271 agggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agatatggta gcagcagctg gtaccccctt tgactactgg 120 ggccaggga 129 <210> 8272 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8272 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Met Val Ala Ala 20 25 30 Ala Gly Thr Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8273 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8273 Cys Ala Arg Asp Thr Pro Leu Gly Tyr Cys Ser Gly Gly Ser Cys Pro 1 5 10 15 Asp Ala Phe Asp Ile Trp 20 <210> 8274 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8274 acagcctact tggagctgag gagcctgaga tctgacgaca cggccgtgta ttactgtgcg 60 agagacacac ccctaggata ttgtagtggt ggtagctgtc ctgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8275 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8275 Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Thr Pro Leu Gly Tyr Cys Ser Gly Gly Ser 20 25 30 Cys Pro Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8276 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8276 acagcctaca tggagctgag gagcctgaga tctgacgaca cggccgtgta ttactgtgcg 60 agagacacac ccctaggata ttgtagtggt ggtagctgtc ctgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8277 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8277 Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Thr Pro Leu Gly Tyr Cys Ser Gly Gly Ser 20 25 30 Cys Pro Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8278 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8278 Cys Ala Arg Glu Val Val Ile Ala Ala Arg Ser Pro Phe Asp Tyr Trp 1 5 10 15 <210> 8279 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8279 ccagacacat ccaggaacca gttctccctg cagctgaact ctgtgactcc cgaggacacg 60 gctgtgtatt actgtgcaag agaagtggtt atagcagctc gctccccttt tgactactgg 120 ggccaggga 129 <210> 8280 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8280 Pro Asp Thr Ser Arg Asn Gln Phe Ser Leu Gln Leu Asn Ser Val Thr 1 5 10 15 Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Val Val Ile Ala 20 25 30 Ala Arg Ser Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8281 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8281 ccagacacat ccaagaacca gttctccctg cagctgaact ctgtgactcc cgaggacacg 60 gctgtgtatt actgtgcaag agaagtggtt atagcagctc gctccccttt tgactactgg 120 ggccaggga 129 <210> 8282 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8282 Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser Val Thr 1 5 10 15 Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Val Val Ile Ala 20 25 30 Ala Arg Ser Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8283 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8283 Cys Thr Thr Glu Val Val Ala Ala Thr Pro Val Asp Tyr Trp 1 5 10 <210> 8284 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8284 atctcaaggg atgattcaaa aaacacgctg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacagccg tgtattactg taccacagaa gtggtagctg ctactccggt tgactactgg 120 ggccaggga 129 <210> 8285 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8285 Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Thr Glu Val Val 20 25 30 Ala Ala Thr Pro Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 8286 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8286 atctcaagag atgattcaaa aaacacgctg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacagccg tgtattactg taccacagaa gtggtagctg ctactccggt tgactactgg 120 ggccaggga 129 <210> 8287 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8287 Cys Ala Lys Arg Asp Tyr Tyr Gly Ser Gly His Tyr Trp 1 5 10 <210> 8288 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8288 accatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaag agggattact atggttcagg acactactgg 120 ggccaggga 129 <210> 8289 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8289 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Arg Asp 20 25 30 Tyr Tyr Gly Ser Gly His Tyr Trp Gly Gln Gly 35 40 <210> 8290 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8290 accatctcca gacacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaag agggattact atggttcagg acactactgg 120 ggccaggga 129 <210> 8291 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8291 Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Arg Asp 20 25 30 Tyr Tyr Gly Ser Gly His Tyr Trp Gly Gln Gly 35 40 <210> 8292 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8292 Cys Ala Lys Asp Ala Val Pro Val Thr Val Glu Asp Tyr Asn Trp Phe 1 5 10 15 Asp Ala Trp <210> 8293 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8293 tctgtcaaca cggcctatat actgctcagt ggactaaaga ctgacgacac tgccgtctat 60 tactgtgcca aagatgcggt gccagtcact gttgaggact ataactggtt cgacgcctgg 120 ggtcaggga 129 <210> 8294 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8294 Ser Val Asn Thr Ala Tyr Ile Leu Leu Ser Gly Leu Lys Thr Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Asp Ala Val Pro Val Thr Val Glu 20 25 30 Asp Tyr Asn Trp Phe Asp Ala Trp Gly Gln Gly 35 40 <210> 8295 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8295 tatgtcaaca cggcctatat actgctcagt ggactaaaga ctgacgacac tgccgtctat 60 tactgtgcca aagatgcggt gccagtcact gttgaggact ataactggtt cgacgcctgg 120 ggtcaggga 129 <210> 8296 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8296 Tyr Val Asn Thr Ala Tyr Ile Leu Leu Ser Gly Leu Lys Thr Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Asp Ala Val Pro Val Thr Val Glu 20 25 30 Asp Tyr Asn Trp Phe Asp Ala Trp Gly Gln Gly 35 40 <210> 8297 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8297 Cys Ala Arg Glu Pro Thr Gly Gln Leu Trp Val Arg Asn Trp Phe Asp 1 5 10 15 Pro Trp <210> 8298 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8298 acatccaaga accacgtctc cctgcagctg aactctgtga ctcccgagga cacggctgtc 60 tattattgtg caagagaacc gacaggacag ctatgggtga ggaactggtt cgacccctgg 120 ggccaggga 129 <210> 8299 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8299 Thr Ser Lys Asn His Val Ser Leu Gln Leu Asn Ser Val Thr Pro Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Thr Gly Gln Leu Trp 20 25 30 Val Arg Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8300 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8300 acatccaaga accacgtctc cctgcagctg aaccctgtga ctcccgagga cacggctgtc 60 tattattgtg caagagaacc gacaggacag ctatgggtga ggaactggtt cgacccctgg 120 ggccaggga 129 <210> 8301 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8301 Thr Ser Lys Asn His Val Ser Leu Gln Leu Asn Pro Val Thr Pro Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Pro Thr Gly Gln Leu Trp 20 25 30 Val Arg Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8302 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8302 Cys Ala Lys Ile Leu Ala Thr Tyr Tyr Asp Leu Leu Thr Gly Tyr Ala 1 5 10 15 Leu Asp Tyr Trp 20 <210> 8303 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8303 aaggacacgc ttaatctgca aatgaacagc ctgagaggcg aggacacggc cgtatattac 60 tgtgcgaaaa tattggcgac gtattacgat cttttgactg gttatgctct agactactgg 120 ggccaggga 129 <210> 8304 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8304 Lys Asp Thr Leu Asn Leu Gln Met Asn Ser Leu Arg Gly Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Ile Leu Ala Thr Tyr Tyr Asp Leu Leu 20 25 30 Thr Gly Tyr Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8305 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8305 aaggacacgc tgaatctgca aatgaacagc ctgagagtcg aggacacggc cgtatattac 60 tgtgcgaaaa tattggcgac gtattacgat cttttgactg gttatgctct agactactgg 120 ggccaggga 129 <210> 8306 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8306 Lys Asp Thr Leu Asn Leu Gln Met Asn Ser Leu Arg Val Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Ile Leu Ala Thr Tyr Tyr Asp Leu Leu 20 25 30 Thr Gly Tyr Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8307 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8307 Cys Ala Arg Gly Leu Leu Gly Ser Gly Ser Tyr Tyr Arg Pro Asn Tyr 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 8308 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8308 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagaggactt 60 ttaggttcag ggagttatta ccgcccgaat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8309 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8309 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Leu Leu Gly Ser Gly Ser Tyr Tyr Arg Pro Asn Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8310 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8310 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagaggactt 60 ttaggttcag ggagttatta ccgcccgaat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8311 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8311 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Leu Leu Gly Ser Gly Ser Tyr Tyr Arg Pro Asn Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8312 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8312 Cys Ala Lys Leu Gln Arg Gly Gln Gln Leu Val Ser Pro Ala Leu Asp 1 5 10 15 Tyr Trp <210> 8313 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8313 aattccaaga acacgctgta tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgaaactcca aaggggacag cagctggtat ccccggcgct ggactactgg 120 ggccaggga 129 <210> 8314 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8314 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Leu Gln Arg Gly Gln Gln Leu 20 25 30 Val Ser Pro Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8315 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8315 aattccaaga acacactgta tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgaaactcca aaggggacag cagctggtat ccccggcgct ggactactgg 120 ggccaggga 129 <210> 8316 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8316 Cys Ala His Met Trp Gln Tyr Ser Ser Ser Pro Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 8317 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8317 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca catgtggcaa tatagcagct cgccttactt tgactactgg 120 ggccaggga 129 <210> 8318 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8318 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Met Trp Gln Tyr Ser 20 25 30 Ser Ser Pro Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8319 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8319 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca catgtggcaa tatagcagct cgccttactt tgactactgg 120 ggccaggga 129 <210> 8320 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8320 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Met Trp Gln Tyr Ser 20 25 30 Ser Ser Pro Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8321 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8321 Cys Ala Arg Glu Thr Tyr Tyr Tyr Gly Ser Gly Ser His Gly Asn Phe 1 5 10 15 Asp Tyr Trp <210> 8322 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8322 gccaaggact cactgtatct gcaaatgaac agcctgagag acgaggacac ggctgtgtat 60 tactgtgcga gggaaacgta ttactatggt tcggggagtc atgggaactt tgactactgg 120 ggccaggga 129 <210> 8323 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8323 Ala Lys Asp Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Glu Thr Tyr Tyr Tyr Gly Ser Gly 20 25 30 Ser His Gly Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8324 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8324 gccaagaact cactgtatct gcaaatgaac agcctgagag acgaggacac ggctgtgtat 60 tactgtgcga gggaaacgta ttactatggt tcggggagtc atgggaactt tgactactgg 120 ggccaggga 129 <210> 8325 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8325 Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg Glu Thr Tyr Tyr Tyr Gly Ser Gly 20 25 30 Ser His Gly Asn Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8326 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8326 Cys Ala Lys Asp Arg Asn Gly Gly Ser Gly Ser Tyr Ser Phe Ala Phe 1 5 10 15 Asp Ile Trp <210> 8327 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8327 tccaataact cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aagataggaa cggagggagt gggagctact cttttgcttt tgatatctgg 120 ggccaaggg 129 <210> 8328 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8328 Ser Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Asn Gly Gly Ser Gly Ser 20 25 30 Tyr Ser Phe Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8329 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8329 tccaagaaca cgctgtatct gcaaatgaac agcctgagag ccgaggacac ggccgtatat 60 tactgtgcga aagataggaa cggagggagt gggagctact cttttgcttt tgatatctgg 120 ggccaaggg 129 <210> 8330 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8330 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Asn Gly Gly Ser Gly Ser 20 25 30 Tyr Ser Phe Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8331 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8331 Cys Ala His Val Asn Leu Arg Tyr Phe Ala Ser Gly Asn Phe Tyr Thr 1 5 10 15 Thr Phe Asp Tyr Trp 20 <210> 8332 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8332 aatcaggtgg tccttacaat gaccaacgtg gaccctgtgg acacagccac atatttctgc 60 gcacacgtga atctccggta ctttgcttcg ggaaattttt ataccacttt tgactactgg 120 ggccaggga 129 <210> 8333 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8333 Asn Gln Val Val Leu Thr Met Thr Asn Val Asp Pro Val Asp Thr Ala 1 5 10 15 Thr Tyr Phe Cys Ala His Val Asn Leu Arg Tyr Phe Ala Ser Gly Asn 20 25 30 Phe Tyr Thr Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8334 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8334 aatcaggtgg tccttacaat gaccaacgtg gaccccgtgg acacagccac atatttctgc 60 gcacacgtga atctccggta ctttgcttcg ggaaattttt ataccacttt tgactactgg 120 ggccaggga 129 <210> 8335 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8335 Cys Ala Arg Gly Val Leu Tyr Ser Ser Ser Pro Arg Trp Asp Asp Ala 1 5 10 15 Phe Asp Ile Trp 20 <210> 8336 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8336 acgagcacag cctacatgga gctgaggagc ctgagatctg acgacacggc cgtgtattgc 60 tgtgcgaggg gggtcctgta tagcagctcg ccccgttggg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8337 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8337 Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr 1 5 10 15 Ala Val Tyr Cys Cys Ala Arg Gly Val Leu Tyr Ser Ser Ser Pro Arg 20 25 30 Trp Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8338 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8338 acgagcacag cctacatgga gctgaggagc ctgagatctg acgacacggc cgtgtattac 60 tgtgcgaggg gggtcctgta tagcagctcg ccccgttggg atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8339 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8339 Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Val Leu Tyr Ser Ser Ser Pro Arg 20 25 30 Trp Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8340 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8340 Cys Ala Arg Gln Gly Gly Ser Gly Ser Tyr Thr Tyr Tyr Gly Met Asp 1 5 10 15 Val Trp <210> 8341 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8341 tcgtccaaga accagtgctc cctgaagctg agctctgtga ccgccgcaga cacggctgtg 60 tattactgtg cgagacaggg aggttcgggg agttatacct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8342 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8342 Ser Ser Lys Asn Gln Cys Ser Leu Lys Leu Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gln Gly Gly Ser Gly Ser Tyr 20 25 30 Thr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8343 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8343 acgtccaaga accagttctc cctgaagctg agctctgtga ccgccgcaga cacggctgtg 60 tattactgtg cgagacaggg aggttcgggg agttatacct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8344 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8344 Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gln Gly Gly Ser Gly Ser Tyr 20 25 30 Thr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8345 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8345 Cys Ala Arg Asp Val Asp Ser Ser Gly Trp Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 8346 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8346 gcggacaaat ccacgagcac agcctacatg gagctgagca gcctgagatc tgaggacgcg 60 gccgtgtatt actgtgcgag agacgtggac agcagtggct ggtactactt tgactactgg 120 ggccaggga 129 <210> 8347 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8347 Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Ala Ala Val Tyr Tyr Cys Ala Arg Asp Val Asp Ser Ser 20 25 30 Gly Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8348 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8348 gcggacaaat ccacgagcac agcctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agacgtggac agcagtggct ggtactactt tgactactgg 120 ggccaggga 129 <210> 8349 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8349 Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Val Asp Ser Ser 20 25 30 Gly Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8350 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8350 Cys Ala Arg Asp Ala Arg Glu Val Lys Gln Tyr Arg Gly Phe Asp Pro 1 5 10 15 Trp <210> 8351 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8351 gacaacgcca agaactcgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgcgagaga cgcgagagag gtaaagcagt accgtgggtt cgacccctgg 120 ggccaggga 129 <210> 8352 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8352 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ala Arg Glu Val Lys 20 25 30 Gln Tyr Arg Gly Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8353 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8353 gacaacgcca agaactcact gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgcgagaga cgcgagagag gtaaagcagt accgtgggtt cgacccctgg 120 ggccaggga 129 <210> 8354 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8354 Cys Ile Ala Thr Val Val Ser Pro Leu Asp Tyr Trp 1 5 10 <210> 8355 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8355 ttcaccatct ccatagatta ttcaaagaac acggcttttc tacaaatgaa cagcctggaa 60 accgaggaca cggccgtgta ttactgtatt gctacggtgg taagcccgct tgactactgg 120 ggccaggga 129 <210> 8356 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8356 Phe Thr Ile Ser Ile Asp Tyr Ser Lys Asn Thr Ala Phe Leu Gln Met 1 5 10 15 Asn Ser Leu Glu Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ile Ala Thr 20 25 30 Val Val Ser Pro Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8357 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8357 ttcaccatct ccagagatga ttcaaagaac acggcttttc tacaaatgaa cagcctggaa 60 accgaggaca cggccgtgta ttactgtatt gctacggtgg taagcccgct tgactactgg 120 ggccaggga 129 <210> 8358 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8358 Phe Thr Ile Ser Arg Asp Asp Ser Lys Asn Thr Ala Phe Leu Gln Met 1 5 10 15 Asn Ser Leu Glu Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ile Ala Thr 20 25 30 Val Val Ser Pro Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8359 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8359 Cys Ala Arg Glu Gly Leu Thr Thr Ile Ala Ala Ala Gly Glu Asn Tyr 1 5 10 15 Phe Asp Tyr Trp 20 <210> 8360 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8360 acgagcacag cctacttgga gctgaggagc ctgagatctg acgacacggc cgtgtattac 60 tgtgcgagag agggcctcac gacaatagca gcagctgggg aaaactactt tgactactgg 120 ggccaggga 129 <210> 8361 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8361 Thr Ser Thr Ala Tyr Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Glu Gly Leu Thr Thr Ile Ala Ala Ala 20 25 30 Gly Glu Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8362 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8362 acgagcacag cctacatgga gctgaggagc ctgagatctg acgacacggc cgtgtattac 60 tgtgcgagag agggcctcac gacaatagca gcagctgggg aaaactactt tgactactgg 120 ggccaggga 129 <210> 8363 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8363 Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Glu Gly Leu Thr Thr Ile Ala Ala Ala 20 25 30 Gly Glu Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8364 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8364 Cys Ala Lys Val Ser Pro Tyr Ser Gly Ser Tyr Tyr Phe Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 8365 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8365 tcgatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagtttcgc cgtatagtgg gagctactac ttctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8366 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8366 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Val Ser Pro Tyr Ser Gly Ser Tyr Tyr Phe Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8367 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8367 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagtttcgc cgtatagtgg gagctactac ttctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8368 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8368 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Val Ser Pro Tyr Ser Gly Ser Tyr Tyr Phe Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8369 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8369 Cys Ala Ala Gln Asp Ala Ala Met Val Ala Pro Gly Tyr Tyr Tyr Tyr 1 5 10 15 Ala Met Asp Val Trp 20 <210> 8370 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8370 tgcacagtct acttggagct gagcaggctg aaatttgacg acacggccgt gttttactgt 60 gcggcccagg atgcagctat ggttgcgccg ggctactact actacgctat ggacgtctgg 120 ggccaaggg 129 <210> 8371 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8371 Cys Thr Val Tyr Leu Glu Leu Ser Arg Leu Lys Phe Asp Asp Thr Ala 1 5 10 15 Val Phe Tyr Cys Ala Ala Gln Asp Ala Ala Met Val Ala Pro Gly Tyr 20 25 30 Tyr Tyr Tyr Ala Met Asp Val Trp Gly Gln Gly 35 40 <210> 8372 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8372 agcacagtct acatggagct gagcaggctg aaatttgacg acacggccgt gttttactgt 60 gcggcccagg atgcagctat ggttgcgccg ggctactact actacgctat ggacgtctgg 120 ggccaaggg 129 <210> 8373 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8373 Ser Thr Val Tyr Met Glu Leu Ser Arg Leu Lys Phe Asp Asp Thr Ala 1 5 10 15 Val Phe Tyr Cys Ala Ala Gln Asp Ala Ala Met Val Ala Pro Gly Tyr 20 25 30 Tyr Tyr Tyr Ala Met Asp Val Trp Gly Gln Gly 35 40 <210> 8374 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8374 Cys Ala Arg Glu Asp Ser Gly Ser Asn Gln Phe Asp Tyr Trp 1 5 10 <210> 8375 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8375 atctccatac acaattccaa gaacacgctg tatcttcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagag gatagtggga gcaaccaatt tgactactgg 120 ggccaggga 129 <210> 8376 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8376 Ile Ser Ile His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Asp Ser 20 25 30 Gly Ser Asn Gln Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8377 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8377 atctccagag acaattccaa gaacacgctg tatcttcaaa tgaacagcct gagagccgag 60 gacacggccg tgtattactg tgcgagagag gatagtggga gcaaccaatt tgactactgg 120 ggccaggga 129 <210> 8378 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8378 Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Asp Ser 20 25 30 Gly Ser Asn Gln Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8379 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8379 Cys Ala His Thr Ala Glu Phe Gly Gly Val Ile Val Glu Tyr Tyr Phe 1 5 10 15 Asp Tyr Trp <210> 8380 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8380 tccaaaaacc aggtggtcct tacaatgacc aacatggacc ctgtggacac agccacatat 60 tactgtgcac acacggccga atttggggga gttatcgtag agtactactt tgactactgg 120 ggccaggga 129 <210> 8381 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8381 Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala His Thr Ala Glu Phe Gly Gly Val Ile 20 25 30 Val Glu Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8382 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8382 ctccaaaacc aggtggtcct tacaatgacc aacatggacc ctgtggacac agccacatat 60 tactgtgcac acacggccga atttggggga gttatcgtag agtactactt tgactactgg 120 ggccaggga 129 <210> 8383 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8383 Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp 1 5 10 15 Thr Ala Thr Tyr Tyr Cys Ala His Thr Ala Glu Phe Gly Gly Val Ile 20 25 30 Val Glu Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8384 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8384 Cys Ala Lys Asp Leu Arg Tyr Tyr Tyr Asp Ser Ser Gly Val Asp Trp 1 5 10 15 <210> 8385 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8385 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacgcg 60 gccgtatatt actgtgcgaa agatctgagg tattactatg atagtagtgg ggtcgactgg 120 ggccaggga 129 <210> 8386 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8386 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Ala Ala Val Tyr Tyr Cys Ala Lys Asp Leu Arg Tyr Tyr 20 25 30 Tyr Asp Ser Ser Gly Val Asp Trp Gly Gln Gly 35 40 <210> 8387 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8387 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agatctgagg tattactatg atagtagtgg ggtcgactgg 120 ggccaggga 129 <210> 8388 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8388 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Arg Tyr Tyr 20 25 30 Tyr Asp Ser Ser Gly Val Asp Trp Gly Gln Gly 35 40 <210> 8389 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8389 Cys Ala Lys Asp Glu Asp Ser Gly Tyr Gly Trp Phe Asp Tyr Trp 1 5 10 15 <210> 8390 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8390 tccagagaca attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggctgtgt attactgtgc gaaagatgag gatagtggct acggatggtt tgactactgg 120 ggccaggga 129 <210> 8391 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8391 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Glu Asp Ser 20 25 30 Gly Tyr Gly Trp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8392 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8392 tccagagaca attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggctgtgt actactgtgc gaaagatgag gatagtggct acggatggtt tgactactgg 120 ggccaggga 129 <210> 8393 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8393 Cys Ala Arg Ala Val Ala Gly Ser Ile Thr Met Val Arg Glu Leu Pro 1 5 10 15 Pro Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 8394 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8394 ttggagctga gctggctgag atctgacgac acggccgtgt attactgtgc gagagcagtg 60 gctgggagta ttactatggt tcgggaacta cccccctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8395 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8395 Leu Glu Leu Ser Trp Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Ala Val Ala Gly Ser Ile Thr Met Val Arg Glu Leu Pro Pro 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8396 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8396 atggagctga gcaggctgag atctgacgac acggccgtgt attactgtgc gagagcagtg 60 gctgggagta ttactatggt tcgggaacta cccccctact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8397 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8397 Met Glu Leu Ser Arg Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Ala Val Ala Gly Ser Ile Thr Met Val Arg Glu Leu Pro Pro 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8398 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8398 Cys Ala Arg Arg Gly Thr Gly Ala Asp Asp Ala Phe Asp Ile Trp 1 5 10 15 <210> 8399 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8399 tcagccgaca ggtccatcag caccgcctac ctgcagtgga gcagcctgaa ggcctcggac 60 accgccatgt atcactgtgc gagacgggga actggagcag atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8400 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8400 Ser Ala Asp Arg Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu 1 5 10 15 Lys Ala Ser Asp Thr Ala Met Tyr His Cys Ala Arg Arg Gly Thr Gly 20 25 30 Ala Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8401 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8401 tcagccgaca agtccatcag caccgcctac ctgcagtgga gcagcctgaa ggcctcggac 60 accgccatgt attactgtgc gagacgggga actggagcag atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8402 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8402 Ser Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu 1 5 10 15 Lys Ala Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Arg Gly Thr Gly 20 25 30 Ala Asp Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8403 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8403 Cys Ala Arg Ala Pro Asp Tyr Tyr Gly Ser Gly Arg His Phe Asp Tyr 1 5 10 15 Trp <210> 8404 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8404 gacacctcca aaaaccaggt ggtcctttca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacgcgc cccggattac tatggttcgg ggagacactt tgactactgg 120 ggccaggga 129 <210> 8405 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8405 Asp Thr Ser Lys Asn Gln Val Val Leu Ser Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ala Pro Asp Tyr Tyr Gly 20 25 30 Ser Gly Arg His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8406 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8406 ggacacctcc aaaaccaggt ggtcctttca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacgcgc cccggattac tatggttcgg ggagacactt tgactactgg 120 ggccaggga 129 <210> 8407 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8407 Gly His Leu Gln Asn Gln Val Val Leu Ser Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ala Pro Asp Tyr Tyr Gly 20 25 30 Ser Gly Arg His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8408 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8408 Cys Ala Arg Leu Asn Asp Thr Ser Ser Phe Asp Tyr Trp 1 5 10 <210> 8409 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8409 accatcagcc cagacacatc caagaaccag ttctccctgc agctgaactc tgtgactccc 60 gaggacacgg ctgtttatta ttgtgcaaga cttaatgaca cctcgtcctt tgactactgg 120 ggcctggga 129 <210> 8410 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8410 Thr Ile Ser Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Asn 20 25 30 Asp Thr Ser Ser Phe Asp Tyr Trp Gly Leu Gly 35 40 <210> 8411 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8411 accatcaacc cagacacatc caagaaccag ttctccctgc agctgaactc tgtgactccc 60 gaggacacgg ctgtgtattt ttgtgcaaga cttaatgaca cctcgtcctt tgactactgg 120 ggcctggga 129 <210> 8412 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8412 Thr Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn 1 5 10 15 Ser Val Thr Pro Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Leu Asn 20 25 30 Asp Thr Ser Ser Phe Asp Tyr Trp Gly Leu Gly 35 40 <210> 8413 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8413 Cys Ala Lys Gly Tyr Asp Phe Trp Ser His Tyr Gln Asn Asp Cys Trp 1 5 10 15 <210> 8414 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8414 agagacaatt ccaagaacac gctatatcta caaatgaaca gcctgagagc cgaggacacg 60 gccctatatt actgtgcgaa aggatacgat ttttggagtc attatcaaaa tgactgctgg 120 ggccaggga 129 <210> 8415 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8415 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Gly Tyr Asp Phe Trp 20 25 30 Ser His Tyr Gln Asn Asp Cys Trp Gly Gln Gly 35 40 <210> 8416 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8416 agagacaatt ccaacaacac gatatatcta caaatgaaca gcctgagagc cgaggacacg 60 gccctatatt actgtgcgaa aggatacgat ttttggagtc attatcaaaa tgactgctgg 120 ggccaggga 129 <210> 8417 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8417 Arg Asp Asn Ser Asn Asn Thr Ile Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Gly Tyr Asp Phe Trp 20 25 30 Ser His Tyr Gln Asn Asp Cys Trp Gly Gln Gly 35 40 <210> 8418 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8418 Cys Gly Arg Gly Ser Phe Pro Ser Ser Ser Ala Phe Trp 1 5 10 <210> 8419 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8419 tacatatcac ttgacacgtc caagaaccag ttctccctga acctgacctc tgtgaccgcc 60 gcggacacgg ccgtgtatta ttgtgggaga gggtcatttc catcaagttc tgccttctgg 120 ggccaggga 129 <210> 8420 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8420 Tyr Ile Ser Leu Asp Thr Ser Lys Asn Gln Phe Ser Leu Asn Leu Thr 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Gly Arg Gly Ser 20 25 30 Phe Pro Ser Ser Ser Ala Phe Trp Gly Gln Gly 35 40 <210> 8421 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8421 accatatcac ttgacacgtc caagaaccag ttctccctga acctgacctc tgtgaccgcc 60 gcggacacgg ccgtgtatta ttgtgggaga gggtcatttc catcaagttc tgccttctgg 120 ggccaggga 129 <210> 8422 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8422 Thr Ile Ser Leu Asp Thr Ser Lys Asn Gln Phe Ser Leu Asn Leu Thr 1 5 10 15 Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Gly Arg Gly Ser 20 25 30 Phe Pro Ser Ser Ser Ala Phe Trp Gly Gln Gly 35 40 <210> 8423 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8423 Cys Ala His Arg Leu Asn Gly Gly Gly Gly Phe Asp Tyr Trp 1 5 10 <210> 8424 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8424 catcaccaag gacacctcca aaaccaggtg gtcctcagaa tgaccaacat ggaccctgtg 60 gacacagcca catattactg tgcacacaga cttaatggtg gaggcggctt tgactactgg 120 ggccaggga 129 <210> 8425 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8425 His His Gln Gly His Leu Gln Asn Gln Val Val Leu Arg Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Leu Asn 20 25 30 Gly Gly Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8426 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8426 atcaccaagg acacctccaa aaaccaggtg gtcctcagaa tgaccaacat ggaccctgtg 60 gacacagcca catattactg tgcacacaga cttaatggtg gaggcggctt tgactactgg 120 ggccaggga 129 <210> 8427 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8427 Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Arg Met Thr Asn 1 5 10 15 Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Leu Asn 20 25 30 Gly Gly Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8428 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8428 Cys Val Arg Asp Ser Phe Leu Val Glu Gln Val Ala Pro Ser Trp Gly 1 5 10 15 Cys Asp His Trp 20 <210> 8429 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8429 caaaacacgc agtttctgca aatgagcaac ctgagagtcg aaggctccgc tgtgtatttc 60 tgtgtgagag atagtttttt ggtcgaacaa gtggcgccct cctgggggtg tgaccactgg 120 ggcctggga 129 <210> 8430 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8430 Gln Asn Thr Gln Phe Leu Gln Met Ser Asn Leu Arg Val Glu Gly Ser 1 5 10 15 Ala Val Tyr Phe Cys Val Arg Asp Ser Phe Leu Val Glu Gln Val Ala 20 25 30 Pro Ser Trp Gly Cys Asp His Trp Gly Leu Gly 35 40 <210> 8431 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8431 caaaacacgc agtttctgca aatgagcaac ctgagagtcg aagactccgc tgtgtatttc 60 tgtgtgagag atagtttttt ggtcgaacaa gtggcgccct cctgggggtg tgaccactgg 120 ggcctggga 129 <210> 8432 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8432 Gln Asn Thr Gln Phe Leu Gln Met Ser Asn Leu Arg Val Glu Asp Ser 1 5 10 15 Ala Val Tyr Phe Cys Val Arg Asp Ser Phe Leu Val Glu Gln Val Ala 20 25 30 Pro Ser Trp Gly Cys Asp His Trp Gly Leu Gly 35 40 <210> 8433 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8433 Cys Ala Arg Gly Asp Tyr Ser Asn Tyr Ala Val Met Gly Leu Gly Tyr 1 5 10 15 Trp <210> 8434 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8434 gacaattcca agaacacgct gtatcttcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgcgagggg ggactacagt aactacgctg tgatggggtt gggctactgg 120 ggccaggga 129 <210> 8435 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8435 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp Tyr Ser Asn Tyr 20 25 30 Ala Val Met Gly Leu Gly Tyr Trp Gly Gln Gly 35 40 <210> 8436 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8436 gacaattcca acaacacgct gtatcttcaa atgaacagcc tgagagccga ggacacggcc 60 gtgtattact gtgcgagggg ggactacagt aactacgctg tgatggggtt gggctactgg 120 ggccaggga 129 <210> 8437 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8437 Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asp Tyr Ser Asn Tyr 20 25 30 Ala Val Met Gly Leu Gly Tyr Trp Gly Gln Gly 35 40 <210> 8438 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8438 Cys Ala Lys Gly Asp Ser Gly Ser Tyr Tyr Gly Ser Ser His Phe Asp 1 5 10 15 Tyr Trp <210> 8439 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8439 aacgccaaga actccctgta tctgcaaatg agcagtctga gagctgagga cacggccttg 60 tattactgtg caaaagggga tagtgggagc tactacgggt cgtcccactt tgactactgg 120 ggccaggga 129 <210> 8440 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8440 Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Ser Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Gly Asp Ser Gly Ser Tyr Tyr 20 25 30 Gly Ser Ser His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8441 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8441 aacgccaaga actccctgta tctgcaaatg aacagtctga gagctgagga cacggccttg 60 tattactgtg caaaagggga tagtgggagc tactacgggt cgtcccactt tgactactgg 120 ggccaggga 129 <210> 8442 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8442 Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Gly Asp Ser Gly Ser Tyr Tyr 20 25 30 Gly Ser Ser His Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8443 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8443 Cys Ala Lys Asp Gly Arg Gly Tyr Ser Ser Ser Trp Tyr Gly Tyr Asp 1 5 10 15 Tyr Tyr Tyr Gly Met Asp Val Trp 20 <210> 8444 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8444 tatctgcaaa tgaacagcct gagagccgag gacacggctg tgtattactg tgcgaaagat 60 gggagggggt atagcagcag ctggtatggt tacgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8445 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8445 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Gly Arg Gly Tyr Ser Ser Ser Trp Tyr Gly Tyr Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8446 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8446 tatctgcaaa tgaacagccc gagagccgaa gacacggctg tgtattactg tgcgaaagat 60 gggagggggt atagcagcag ctggtatggt tacgactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8447 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8447 Tyr Leu Gln Met Asn Ser Pro Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Gly Arg Gly Tyr Ser Ser Ser Trp Tyr Gly Tyr Asp 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8448 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8448 Cys Ala Arg Leu Phe Ser Arg Glu Gly Leu Asp Ala Phe Asp Ile Trp 1 5 10 15 <210> 8449 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8449 gccgacaagt ccatcagcac cgcctacctg cagtggagca gcctgaaggc ctcggacacc 60 gccatgtatt actgtgcgag acttttttct cgggaggggt tagatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8450 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8450 Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys 1 5 10 15 Ala Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Leu Phe Ser Arg Glu 20 25 30 Gly Leu Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8451 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8451 Cys Ala Ala Ala Thr Ser Gly Phe Leu Glu Trp Leu Ser Pro Pro Thr 1 5 10 15 Asn Leu Asp Tyr Trp 20 <210> 8452 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8452 tgcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcggccgcga catccggatt tttggagtgg ttatcccccc ccacaaatct tgactactgg 120 ggccaggga 129 <210> 8453 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8453 Cys Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Ala Ala Thr Ser Gly Phe Leu Glu Trp Leu Ser 20 25 30 Pro Pro Thr Asn Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8454 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8454 agcacagcct acatggagct gaggagcctg agatctgacg acacggccgt gtattactgt 60 gcggccgcga catccggatt tttggagtgg ttatcccccc ccacaaatct tgactactgg 120 ggccaggga 129 <210> 8455 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8455 Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Ala Ala Thr Ser Gly Phe Leu Glu Trp Leu Ser 20 25 30 Pro Pro Thr Asn Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8456 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8456 Cys Ala Arg Pro Arg Ala Pro Thr Thr Asn Tyr Tyr Tyr Gly Met Asp 1 5 10 15 Val Trp <210> 8457 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8457 acctctgtca gcacggcata tctgcagatc agcagcctaa aggctgagga cactgccgtg 60 tattactgtg cgaggccacg ggcacctacc acaaactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8458 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8458 Thr Ser Val Ser Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Pro Arg Ala Pro Thr Thr Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8459 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8459 acctctgtca gcacggcata tctgcagatc agcagcctaa aggctgagga cactgccgtg 60 tattactgtg cgaggccacg ggcacctacc acaaactact actacggtat ggacgtctgg 120 agccaaggg 129 <210> 8460 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8460 Thr Ser Val Ser Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Pro Arg Ala Pro Thr Thr Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Ser Gln Gly 35 40 <210> 8461 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8461 Cys Ala Arg Glu Trp Glu Ser Ile Ala Ala Arg Phe Asp Leu Trp 1 5 10 15 <210> 8462 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8462 ttggcggaca aggccacgac cacagtctac atggaattca aaagtctgag atctgaggac 60 acggccgttt atttctgtgc gagagagtgg gagagcatag cagctcgctt tgacctctgg 120 ggccaggga 129 <210> 8463 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8463 Leu Ala Asp Lys Ala Thr Thr Thr Val Tyr Met Glu Phe Lys Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Glu Trp Glu Ser 20 25 30 Ile Ala Ala Arg Phe Asp Leu Trp Gly Gln Gly 35 40 <210> 8464 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8464 atggcggaca aggccacgac cacagtctac atggaattca aaagtctgag atctgaggac 60 acggccgttt atttctgtgc gagagagtgg gagagcatag cagctcgctt tgacctctgg 120 ggccaggga 129 <210> 8465 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8465 Met Ala Asp Lys Ala Thr Thr Thr Val Tyr Met Glu Phe Lys Ser Leu 1 5 10 15 Arg Ser Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Glu Trp Glu Ser 20 25 30 Ile Ala Ala Arg Phe Asp Leu Trp Gly Gln Gly 35 40 <210> 8466 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8466 Cys Ala Arg Gly Ala Leu Leu Glu Trp Leu Ser Arg Phe Asp Asn Trp 1 5 10 15 <210> 8467 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8467 gtagacacgt ccaagaacct gttctccctg aagctgagct ctgtgaccgc cgcggacacg 60 gccgtatatt actgtgcgag aggtgcactt ttggagtggt tatcccgctt tgacaactgg 120 ggccaggga 129 <210> 8468 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8468 Val Asp Thr Ser Lys Asn Leu Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Ala Leu Leu Glu 20 25 30 Trp Leu Ser Arg Phe Asp Asn Trp Gly Gln Gly 35 40 <210> 8469 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8469 gtagacacgt ccaagaacca gttctccctg aagctgagct ctgtgaccgc cgcggacacg 60 gccgtatatt actgtgcgag aggtgcactt ttggagtggt tatcccgctt tgacaactgg 120 ggccaggga 129 <210> 8470 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8470 Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Ala Leu Leu Glu 20 25 30 Trp Leu Ser Arg Phe Asp Asn Trp Gly Gln Gly 35 40 <210> 8471 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8471 Cys Ala Arg Gly Gln Ala Asp Pro Met Leu Gly Ile Tyr Arg Pro Phe 1 5 10 15 Val Phe Asp Tyr Trp 20 <210> 8472 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8472 tcccagttct ccctggaggt gacttctgtg accgccacgg acacggctgt ttattactgt 60 gcgagaggcc aagcggaccc catgttgggg atataccgcc cgttcgtctt tgactactgg 120 ggccaggga 129 <210> 8473 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8473 Ser Gln Phe Ser Leu Glu Val Thr Ser Val Thr Ala Thr Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Gln Ala Asp Pro Met Leu Gly Ile Tyr 20 25 30 Arg Pro Phe Val Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8474 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8474 acccagttct ccctggaggt gacttctgtg accgccacgg acacggctgt ttattactgt 60 gcgagaggcc aagcggaccc catgttgggg atataccgcc cgttcgtctt tgactactgg 120 ggccaggga 129 <210> 8475 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8475 Thr Gln Phe Ser Leu Glu Val Thr Ser Val Thr Ala Thr Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Gln Ala Asp Pro Met Leu Gly Ile Tyr 20 25 30 Arg Pro Phe Val Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8476 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8476 Cys Ala Arg Gly Ile Val Val Ile Pro Ala Ala Asn Pro Asp Phe Asp 1 5 10 15 Tyr Trp <210> 8477 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8477 acctccaaaa accaggtggc ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacgcggtat tgtagtaata ccagctgcta atcccgactt tgactactgg 120 ggccaggga 129 <210> 8478 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8478 Thr Ser Lys Asn Gln Val Ala Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Gly Ile Val Val Ile Pro Ala 20 25 30 Ala Asn Pro Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8479 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8479 cacctccaaa aaccaggtgg ccctacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacgcggtat tgtagtaata ccagctgcta atcccgactt tgactactgg 120 ggccaggga 129 <210> 8480 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8480 His Leu Gln Lys Pro Gly Gly Pro Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Gly Ile Val Val Ile Pro Ala 20 25 30 Ala Asn Pro Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8481 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8481 Cys Ala Lys Gly Gly Tyr Arg Gln Gly Tyr Phe Asp Tyr Trp 1 5 10 <210> 8482 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8482 atctccatat atgattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaggc ggctaccgac aggggtactt tgactactgg 120 ggccaggga 129 <210> 8483 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8483 Ile Ser Ile Tyr Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Tyr 20 25 30 Arg Gln Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8484 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8484 atctccagag atgattccaa gaacacgctg tatctgcaaa tgaacagcct gagagccgag 60 gacacggccg tatattactg tgcgaaaggc ggctaccgac aggggtactt tgactactgg 120 ggccaggga 129 <210> 8485 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8485 Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Tyr 20 25 30 Arg Gln Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8486 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8486 Cys Ala Lys Ser Gly Gly Ala Ser Cys Cys Thr Asn Gly Gly Asp Trp 1 5 10 15 Phe Asp Pro Trp 20 <210> 8487 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8487 aagaactccc tgtatctgca aatgaacggt ctgagagctg aggacacggc cttgtattac 60 tgtgcaaaat caggcggtgc cagctgctgc acaaacgggg gggactggtt cgacccctgg 120 ggccaggga 129 <210> 8488 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8488 Lys Asn Ser Leu Tyr Leu Gln Met Asn Gly Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Leu Tyr Tyr Cys Ala Lys Ser Gly Gly Ala Ser Cys Cys Thr Asn 20 25 30 Gly Gly Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8489 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8489 aagaactccc tgtatctgca aatgaacagt ctgagagctg aggacacggc cttgtattac 60 tgtgcaaaat caggcggtgc cagctgctgc acaaacgggg gggactggtt cgacccctgg 120 ggccaggga 129 <210> 8490 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8490 Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Leu Tyr Tyr Cys Ala Lys Ser Gly Gly Ala Ser Cys Cys Thr Asn 20 25 30 Gly Gly Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8491 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8491 Cys Ala Arg Val Gly Tyr Asp Phe Trp Ser Gly Leu Ser Pro Asp Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 8492 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8492 tgcacagtct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagtag gttacgattt ttggagtggc ctcagccccg actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8493 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8493 Cys Thr Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Val Gly Tyr Asp Phe Trp Ser Gly Leu Ser 20 25 30 Pro Asp Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8494 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8494 agcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagtag gttacgattt ttggagtggc ctcagccccg actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8495 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8495 Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Val Gly Tyr Asp Phe Trp Ser Gly Leu Ser 20 25 30 Pro Asp Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8496 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8496 Cys Ala Arg Leu Ser Val Ile Ala Ala Ala Gly Thr Val Asp Tyr Trp 1 5 10 15 <210> 8497 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8497 tgggacaacg ccaagagctc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgccag attatctgtt atagcagcag ctggtaccgt tgactactgg 120 ggccaggga 129 <210> 8498 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8498 Trp Asp Asn Ala Lys Ser Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Ser Val Ile Ala 20 25 30 Ala Ala Gly Thr Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 8499 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8499 agggacaacg ccaagagctc actgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtgtatt actgtgccag attatctgtt atagcagcag ctggtaccgt tgactactgg 120 ggccaggga 129 <210> 8500 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8500 Arg Asp Asn Ala Lys Ser Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Ser Val Ile Ala 20 25 30 Ala Ala Gly Thr Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 8501 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8501 Cys Ala Ser Leu Ser Arg Gly Tyr Arg Phe Asp Tyr Trp 1 5 10 <210> 8502 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8502 accattaccc ggcacacatc cgcgagcaca gcctacatgg agctgagcag cctgagatct 60 gaagacacgg ctgtgtatta ctgtgcgagt cttagtcgtg gttatcggtt tgactactgg 120 ggccaggga 129 <210> 8503 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8503 Thr Ile Thr Arg His Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Leu Ser 20 25 30 Arg Gly Tyr Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8504 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8504 accattacca gggacacatc cgcgagcaca gcctacatgg agctgagcag cctgagatct 60 gaagacacgg ctgtgtatta ctgtgcgagt cttagtcgtg gttatcggtt tgactactgg 120 ggccaggga 129 <210> 8505 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8505 Thr Ile Thr Arg Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Leu Ser 20 25 30 Arg Gly Tyr Arg Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8506 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8506 Cys Ala Ala Glu Tyr Cys Ser Gly Gly Ser Cys Tyr Pro Pro Leu Asp 1 5 10 15 Ala Phe Asp Ile Trp 20 <210> 8507 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8507 agcactgcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcggccgaat attgtagtgg tggtagctgc tacccccccc ttgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8508 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8508 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Ala Glu Tyr Cys Ser Gly Gly Ser Cys Tyr Pro 20 25 30 Pro Leu Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8509 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8509 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcggccgaat attgtagtgg tggtagctgc tacccccccc ttgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8510 <211> 30 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8510 Cys Ala Lys Asp Leu Val Pro Tyr Tyr Tyr Asp Ser Ser Gly Tyr Tyr 1 5 10 15 Leu Val Gly Phe Gly Ala Gly Asn Tyr Gly Met Asp Val Trp 20 25 30 <210> 8511 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8511 ctgagagccg aggacacggc cgtatattac tgtgcgaaag atctagtccc gtattactat 60 gatagtagtg gttattactt agtcgggttc ggcgccggga actacggtat ggacgtctgg 120 ggccagggg 129 <210> 8512 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8512 Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Leu Val 1 5 10 15 Pro Tyr Tyr Tyr Asp Ser Ser Gly Tyr Tyr Leu Val Gly Phe Gly Ala 20 25 30 Gly Asn Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8513 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8513 ctgagagccg aggacacggc cgtatattac tgtgcgaaag atctagtccc gtattactat 60 gatagtagtg gttattactt agtcgggttc ggcgccggga actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8514 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8514 Cys Ala Lys Asp Thr Ser Ile Glu Tyr Ser Ser Ser Ser Gly Gly Gly 1 5 10 15 Ser Phe Asp Tyr Trp 20 <210> 8515 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8515 aactccctgt atctgcaaat gaacagtctg agagctgagg acacggcctt gtattactgt 60 gcaaaagata cgagcatcga gtatagcagc tcgtccgggg ggggtagttt tgactactgg 120 ggccaggga 129 <210> 8516 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8516 Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Leu Tyr Tyr Cys Ala Lys Asp Thr Ser Ile Glu Tyr Ser Ser Ser Ser 20 25 30 Gly Gly Gly Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8517 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8517 Cys Ala His Gly Asn Pro Tyr Tyr Leu Asp Tyr Trp 1 5 10 <210> 8518 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8518 gctcaccatc accaaggaca cctccaaaac caggtggtcc ttacaatgac caacatggac 60 cctgtggaca cagccacata ttactgtgca cacggtaatc cctactacct tgactactgg 120 ggccaggga 129 <210> 8519 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8519 Ala His His His Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met 1 5 10 15 Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly 20 25 30 Asn Pro Tyr Tyr Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8520 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8520 ctcaccatca ccaaggacac ctccaaaaac caggtggtcc ttacaatgac caacatggac 60 cctgtggaca cagccacata ttactgtgca cacggtaatc cctactacct tgactactgg 120 ggccaggga 129 <210> 8521 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8521 Leu Thr Ile Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met 1 5 10 15 Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly 20 25 30 Asn Pro Tyr Tyr Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8522 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8522 Cys Ala Arg Gln Glu Leu Trp Ser Phe Asp Tyr Trp 1 5 10 <210> 8523 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8523 gtcaccatct cagccgacaa gtccatcagc accgcctacc tgcagtggag cagcctgaag 60 gcctcggaca ccgccatgta ttactgtgcg agacaggagc tatggtcctt tgactactgg 120 ggccaggga 129 <210> 8524 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8524 Val Thr Ile Ser Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp 1 5 10 15 Ser Ser Leu Lys Ala Ser Asp Thr Ala Met Tyr Tyr Cys Ala Arg Gln 20 25 30 Glu Leu Trp Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8525 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8525 gccaccatct cagccgacaa gtccatcagc accgcctacc tgcagtggag cagcctgaag 60 gcctcggaca ccgccatgtg ttactgtgcg agacaggagc tatggtcctt tgactactgg 120 ggccaggga 129 <210> 8526 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8526 Ala Thr Ile Ser Ala Asp Lys Ser Ile Ser Thr Ala Tyr Leu Gln Trp 1 5 10 15 Ser Ser Leu Lys Ala Ser Asp Thr Ala Met Cys Tyr Cys Ala Arg Gln 20 25 30 Glu Leu Trp Ser Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8527 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8527 Cys Ala Arg Ile Arg Tyr Leu Val Gly Leu Gly Asp Phe Thr His Asp 1 5 10 15 Tyr Trp <210> 8528 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8528 acctccaaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccacg 60 tattactgtg cacggatacg ttatttagtg gggttggggg atttcaccca tgactactgg 120 ggccaggga 129 <210> 8529 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8529 Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Arg Tyr Leu Val Gly Leu 20 25 30 Gly Asp Phe Thr His Asp Tyr Trp Gly Gln Gly 35 40 <210> 8530 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8530 cacctccaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccacg 60 tattactgtg cacggatacg ttatttagtg gggttggggg atttcaccca tgactactgg 120 ggccaggga 129 <210> 8531 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8531 His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Ile Arg Tyr Leu Val Gly Leu 20 25 30 Gly Asp Phe Thr His Asp Tyr Trp Gly Gln Gly 35 40 <210> 8532 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8532 Cys Ala Gln Lys Ala Gly Thr Ala Ala Glu Gly Tyr Trp Tyr Phe Asp 1 5 10 15 Leu Trp <210> 8533 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8533 acctccaaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacagaaagc tggtacagcg gcggagggtt actggtactt cgatctctgg 120 ggccgtggc 129 <210> 8534 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8534 Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala Gln Lys Ala Gly Thr Ala Ala Glu 20 25 30 Gly Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8535 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8535 cacctccaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacagaaagc tggtacagcg gcggagggtt actggtactt cgatctctgg 120 ggccgtggc 129 <210> 8536 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8536 His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala Gln Lys Ala Gly Thr Ala Ala Glu 20 25 30 Gly Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8537 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8537 Cys Ala Arg Asp Pro His Tyr Asp Arg Gly Tyr Gly Met Asp Val Trp 1 5 10 15 <210> 8538 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8538 tgggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agatccccat tacgaccgtg gctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8539 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8539 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro His Tyr Asp 20 25 30 Arg Gly Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8540 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8540 agggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agatccccat tacgaccgtg gctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8541 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8541 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro His Tyr Asp 20 25 30 Arg Gly Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8542 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8542 Cys Ala Lys Gly Gly Tyr Gly Ser Asp Tyr Gly Leu Asp Tyr Trp 1 5 10 15 <210> 8543 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8543 tccagagata attccaagaa cacgctgtat ctgcaattga acagcctgag agccgacgac 60 acggccgtat attactgtgc gaaagggggc tatggttcgg actatggact tgactactgg 120 ggccaggga 129 <210> 8544 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8544 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Leu Asn Ser Leu 1 5 10 15 Arg Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Tyr Gly 20 25 30 Ser Asp Tyr Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8545 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8545 tccagagata attccaagaa cacgctgcat ctgcaattga acagcctgag agccgacgac 60 acggccgtat attactgtgc gaaagggggc tatggttcgg actatggact tgactactgg 120 ggccaggga 129 <210> 8546 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8546 Ser Arg Asp Asn Ser Lys Asn Thr Leu His Leu Gln Leu Asn Ser Leu 1 5 10 15 Arg Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gly Tyr Gly 20 25 30 Ser Asp Tyr Gly Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8547 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8547 Cys Ala Arg Asp Arg Ile Ala Gly Asp Ala Phe Asp Ile Trp 1 5 10 <210> 8548 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8548 atcaacccag acacatccaa gaaccagttc tccctgcagc tgaactctgt gactcccgag 60 gacacggctg tgtattactg tgcaagagat cgcatagcag gagatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8549 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8549 Ile Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Ile 20 25 30 Ala Gly Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8550 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8550 atatcagtag acacgtccaa gaaccagttc tccctgcagc tgaactctgt gactcccgag 60 gacacggctg tgtattactg tgcaagagat cgcatagcag gagatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8551 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8551 Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser 1 5 10 15 Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Ile 20 25 30 Ala Gly Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8552 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8552 Cys Ala Arg Asp Leu Gly Gln Trp Pro Gly Tyr Trp 1 5 10 <210> 8553 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8553 ttcaccatct ccagagacaa ttccaagaac acgctgtatc ttcaaatgaa cagcctgaga 60 gccgaggaca cggccgtgta ttactgtgcg agagacctag ggcagtggcc cggctactgg 120 ggccaggga 129 <210> 8554 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8554 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Leu Gly Gln Trp Pro Gly Tyr Trp Gly Gln Gly 35 40 <210> 8555 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8555 ttcaccatct ccagacacaa ttccaagaac acgctgtatc ttcaaatcaa cagcctgaga 60 gccgaggaca cggccgtgta ttactgtgcg agagacctag ggcagtggcc cggctactgg 120 ggccaggga 129 <210> 8556 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8556 Phe Thr Ile Ser Arg His Asn Ser Lys Asn Thr Leu Tyr Leu Gln Ile 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp 20 25 30 Leu Gly Gln Trp Pro Gly Tyr Trp Gly Gln Gly 35 40 <210> 8557 <211> 10 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8557 Cys Ala Lys Asp Leu Ala Met Asp Tyr Trp 1 5 10 <210> 8558 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8558 ggccggttca ccatctccag atataattcc aagaacacgc tgtatctgca aattaacagc 60 ctgagagccg aggacacggc cgtatattac tgtgcgaaag atctggcaat ggactactgg 120 ggccaggga 129 <210> 8559 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8559 Gly Arg Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Thr Leu Tyr Leu 1 5 10 15 Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Lys Asp Leu Ala Met Asp Tyr Trp Gly Gln Gly 35 40 <210> 8560 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8560 ggccggttca ccatctccag agataattcc aagaacacgc tgtatctgca aatgaacagc 60 ctgagagccg aggacacggc cgtatattac tgtgcgaaag atctggcaat ggactactgg 120 ggccaggga 129 <210> 8561 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8561 Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu 1 5 10 15 Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala 20 25 30 Lys Asp Leu Ala Met Asp Tyr Trp Gly Gln Gly 35 40 <210> 8562 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8562 Cys Ala Lys Ile Gly Ala Arg Ser Thr Ser Gly Arg Gly Ala Phe Asp 1 5 10 15 Ile Trp <210> 8563 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8563 aattctaagt acacgatgta tctgcaaatg aacagcctga gagcggagga cacggccgta 60 tattactgtg cgaaaatcgg ggcacgtagt accagcggca ggggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 8564 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8564 Asn Ser Lys Tyr Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ile Gly Ala Arg Ser Thr Ser 20 25 30 Gly Arg Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8565 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8565 aattccaaga acacgctgta tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgaaaatcgg ggcacgtagt accagcggca ggggtgcttt tgatatctgg 120 ggccaaggg 129 <210> 8566 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8566 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ile Gly Ala Arg Ser Thr Ser 20 25 30 Gly Arg Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8567 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8567 Cys Ala Lys Asp Ser Tyr Tyr Tyr Gly Ser Gly Ser Tyr Tyr Asn Asp 1 5 10 15 Ala Phe Asp Ile Trp 20 <210> 8568 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8568 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatt cgtattacta tggttcgggg agttattaca atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8569 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8569 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Ser Tyr Tyr Tyr Gly Ser Gly Ser Tyr 20 25 30 Tyr Asn Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8570 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8570 aacacgctgt atatgaaaat gaacagcctg agagccgagg acacggccgt atattactgt 60 gcgaaagatt cgtattacta tggttcgggg agttattaca atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8571 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8571 Asn Thr Leu Tyr Met Lys Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Ser Tyr Tyr Tyr Gly Ser Gly Ser Tyr 20 25 30 Tyr Asn Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8572 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8572 Cys Ala Arg Gly Gly Gly Ala Tyr Cys Gly Ser Asp Cys Tyr Arg Met 1 5 10 15 Leu Asp Tyr Trp 20 <210> 8573 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8573 gagaacacac tctatcttca aatgaacagc ctgagagccg aggacacggc cgtatattac 60 tgtgcgagag gtggcggggc atattgtggt agtgactgct atcgaatgct tgactactgg 120 ggccacgga 129 <210> 8574 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8574 Glu Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Gly Gly Ala Tyr Cys Gly Ser Asp 20 25 30 Cys Tyr Arg Met Leu Asp Tyr Trp Gly His Gly 35 40 <210> 8575 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8575 gacaacacac tctatcttca aatcaacagc ctgagagccg aggacacggc cgtatattac 60 tgtgcgagag gtggcggggc atattgtggt agtgactgct atcgaatgct tgactactgg 120 ggccacgga 129 <210> 8576 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8576 Asp Asn Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Gly Gly Ala Tyr Cys Gly Ser Asp 20 25 30 Cys Tyr Arg Met Leu Asp Tyr Trp Gly His Gly 35 40 <210> 8577 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8577 Cys Ala Arg Gly Gly Glu Tyr Cys Ser Gly Ala Asn Cys Tyr Ser Gly 1 5 10 15 Phe Asp Tyr Trp 20 <210> 8578 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8578 aagaacaccc tgtatcttca aatgaacagc ctgagagccg aggacacggc cgtgtattac 60 tgtgcgagag ggggggaata ttgtagtggt gctaactgct actcaggatt tgactactgg 120 ggccaggga 129 <210> 8579 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8579 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Gly Glu Tyr Cys Ser Gly Ala Asn 20 25 30 Cys Tyr Ser Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8580 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8580 aacaacaccc tgtatctaca aatgaacagc ctgagagccg aggacacggc cgtgtattac 60 tgtgcgagag ggggggaata ttgtagtggt gctaactgct actcaggatt tgactactgg 120 ggccaggga 129 <210> 8581 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8581 Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly Gly Glu Tyr Cys Ser Gly Ala Asn 20 25 30 Cys Tyr Ser Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8582 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8582 Cys Ala Arg Val Asp Ile Ala Ala Ala Gly Gly Tyr Tyr Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 8583 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8583 acagcctaca tggagctgag gagcctgaga tctgacgaca cggccgtgta ttactgtgcg 60 agagtggata tagcagcagc tggggggtat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8584 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8584 Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Val Asp Ile Ala Ala Ala Gly Gly Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8585 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8585 aaagcctaca tggtgctgag gagcctgaga tctgacgaca cggccgtgta ttactgtgcg 60 agagtggata tagcagcagc tggggggtat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8586 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8586 Lys Ala Tyr Met Val Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Val Asp Ile Ala Ala Ala Gly Gly Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8587 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8587 Cys Thr Pro Ser Asn Arg Gly Val Ile Ile Phe Ala Tyr Trp 1 5 10 <210> 8588 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8588 atctcaagag atgattcaaa aaatacgctg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacagccg tgtattactg tactccctcg aatcggggag ttattatttt tgcctactgg 120 ggccaggga 129 <210> 8589 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8589 Ile Ser Arg Asp Asp Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Thr Pro Ser Asn Arg 20 25 30 Gly Val Ile Ile Phe Ala Tyr Trp Gly Gln Gly 35 40 <210> 8590 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8590 atctcaagag atgattcaaa aaacacgctg tatctgcaaa tgaacagcct gaaaaccgag 60 gacacagccg tgtattactg tactccctcg aatcggggag ttattatttt tgcctactgg 120 ggccaggga 129 <210> 8591 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8591 Cys Ala Arg Asp Lys Tyr Tyr Asp Ile Leu Thr Gly Ser Ala Glu Asn 1 5 10 15 Tyr Tyr Phe Asp Tyr Trp 20 <210> 8592 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8592 acagtctact tggagctgag cagtctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agagataagt attacgatat tttgactggt tctgccgaaa attactactt tgactactgg 120 ggccaggga 129 <210> 8593 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8593 Thr Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Lys Tyr Tyr Asp Ile Leu Thr Gly Ser Ala 20 25 30 Glu Asn Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8594 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8594 acagtctaca tggagctgag cagcctgaga tctgaggaca cggccgtgta ttactgtgcg 60 agagataagt attacgatat tttgactggt tctgccgaaa attactactt tgactactgg 120 ggccaggga 129 <210> 8595 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8595 Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Lys Tyr Tyr Asp Ile Leu Thr Gly Ser Ala 20 25 30 Glu Asn Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8596 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8596 Cys Ala Lys Gly Pro Asn Thr Tyr Tyr Tyr Asp Ser Ser Gly Tyr Tyr 1 5 10 15 Asn Arg Leu Asp Tyr Trp 20 <210> 8597 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8597 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagggccaa atacgtatta ctatgatagt agtggttatt acaatagact tgactactgg 120 ggccaggga 129 <210> 8598 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8598 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Gly Pro Asn Thr Tyr Tyr Tyr Asp Ser Ser Gly 20 25 30 Tyr Tyr Asn Arg Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8599 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8599 aagatgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagggccaa atacgtatta ctatgatagt agtggttatt acaatagact tgactactgg 120 ggccaggga 129 <210> 8600 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8600 Lys Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Gly Pro Asn Thr Tyr Tyr Tyr Asp Ser Ser Gly 20 25 30 Tyr Tyr Asn Arg Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8601 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8601 Cys Ala Lys Pro Ala Pro Gly Tyr Thr Trp Asn Tyr Ala Asp Tyr Trp 1 5 10 15 <210> 8602 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8602 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa acccgctcct gggtatacct ggaattacgc tgactactgg 120 ggccaggga 129 <210> 8603 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8603 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro Ala Pro Gly Tyr 20 25 30 Thr Trp Asn Tyr Ala Asp Tyr Trp Gly Gln Gly 35 40 <210> 8604 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8604 agagacaatt ccaggaacac gctgtctctc caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa acccgctcct gggtatacct ggaattacgc tgactactgg 120 ggccaggga 129 <210> 8605 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8605 Arg Asp Asn Ser Arg Asn Thr Leu Ser Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro Ala Pro Gly Tyr 20 25 30 Thr Trp Asn Tyr Ala Asp Tyr Trp Gly Gln Gly 35 40 <210> 8606 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8606 Cys Ala His Glu Lys Gly Phe Asn Tyr Tyr Asp Ser Ser Gly Tyr Gly 1 5 10 15 Tyr Trp <210> 8607 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8607 acctccaaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacgaaaa aggttttaat tactatgata gtagtggtta tggctactgg 120 ggccaggga 129 <210> 8608 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8608 Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Glu Lys Gly Phe Asn Tyr Tyr 20 25 30 Asp Ser Ser Gly Tyr Gly Tyr Trp Gly Gln Gly 35 40 <210> 8609 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8609 cacctccaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacgaaaa aggttttaat tactatgata gtagtggtta tggctactgg 120 ggccaggga 129 <210> 8610 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8610 His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Glu Lys Gly Phe Asn Tyr Tyr 20 25 30 Asp Ser Ser Gly Tyr Gly Tyr Trp Gly Gln Gly 35 40 <210> 8611 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8611 Cys Thr Thr Asp Phe Phe Leu Tyr Arg His Gln Tyr Cys Ser Gly Gly 1 5 10 15 Ser Cys Tyr Ser Pro Phe Asp Tyr Trp 20 25 <210> 8612 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8612 ctgcaaatga acagcttgaa aaccgaggac acagccgtgt attactgtac cacagatttt 60 tttttgtatc gtcatcaata ttgtagtggt ggtagctgct actccccgtt tgactactgg 120 ggccaggga 129 <210> 8613 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8613 Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Thr Thr Asp Phe Phe Leu Tyr Arg His Gln Tyr Cys Ser Gly Gly Ser 20 25 30 Cys Tyr Ser Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8614 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8614 ctgcaaatga acagcctgaa aaccgaggac acagccgtgt attactgtac cacagatttt 60 tttttgtatc gtcatcaata ttgtagtggt ggtagctgct actccccgtt tgactactgg 120 ggccaggga 129 <210> 8615 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8615 Cys Ala Lys Gly Ser Ser Gly Trp Ser Asp Trp 1 5 10 <210> 8616 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8616 cgattcacca tctccagaga caattccaag aacacgctgt atcttcaaat gaacagcctg 60 agagccgagg acacggccgt gtattactgt gcgaagggta gcagtggctg gtccgactgg 120 ggccaggga 129 <210> 8617 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8617 Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Gly Ser Ser Gly Trp Ser Asp Trp Gly Gln Gly 35 40 <210> 8618 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8618 cgattcacca tctccagaca caataccaag aacacgctgt atcttcaaat gaacagcctg 60 agagccgagg acacggccgt gtattactgt gcgaagggta gcagtggctg gtccgactgg 120 ggccaggga 129 <210> 8619 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8619 Arg Phe Thr Ile Ser Arg His Asn Thr Lys Asn Thr Leu Tyr Leu Gln 1 5 10 15 Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys 20 25 30 Gly Ser Ser Gly Trp Ser Asp Trp Gly Gln Gly 35 40 <210> 8620 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8620 Cys Ala Lys Asp Leu Gly Gly Thr His Tyr Tyr Tyr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 8621 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8621 aagaacacgc tgtatctgca aatgaacagc ctgagagccg aggacacggc cgtatattac 60 tgtgcgaaag atctcggggg gacccactat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8622 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8622 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Asp Leu Gly Gly Thr His Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8623 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8623 aacaacacgc tgtatctgca aatcaacagc ctgagagccg aggacacggc cgtatattac 60 tgtgcgaaag atctcggggg gacccactat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8624 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8624 Asn Asn Thr Leu Tyr Leu Gln Ile Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Asp Leu Gly Gly Thr His Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8625 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8625 Cys Ala Arg His Ser Gly Ser Gly Val Asp Tyr Trp 1 5 10 <210> 8626 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8626 gtcaccatat ccgtagacac gtccaagaac cagttctccc tgaagctgag ctctgtgacc 60 gccgcagaca cggctgtgta ttactgtgcg agacatagtg gtagcggggt tgactactgg 120 ggccaggga 129 <210> 8627 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8627 Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu 1 5 10 15 Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg His 20 25 30 Ser Gly Ser Gly Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 8628 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8628 gtcaccatat ccgtagacac gtccaagaac cagttctccc tgaagctgag ctccgtgacc 60 gccgcagaca cggctgtgta ttactgtgcg agacatagtg gtagcggggt tgactactgg 120 ggccaggga 129 <210> 8629 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8629 Cys Ala Lys Val Gly His Ser Tyr Tyr Phe Asp Tyr Trp 1 5 10 <210> 8630 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8630 accatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gttgggcatt cctactactt tgactactgg 120 ggccaggga 129 <210> 8631 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8631 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly 20 25 30 His Ser Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8632 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8632 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gttgggcatt cctactactt tgactactgg 120 ggccaggga 129 <210> 8633 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8633 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Gly 20 25 30 His Ser Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8634 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8634 Cys Ser Lys Gly Val Gly Ile Thr Ile Phe Gly Val Pro Tyr Tyr Trp 1 5 10 15 <210> 8635 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8635 cagagacaac agcaaaactc cctgtatctg caaatgaaca gtctgacaac tgaggactcc 60 gccttgtatt actgttcaaa aggagtaggt ataacgattt ttggagtgcc ttactactgg 120 ggccaggga 129 <210> 8636 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8636 Gln Arg Gln Gln Gln Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Thr 1 5 10 15 Thr Glu Asp Ser Ala Leu Tyr Tyr Cys Ser Lys Gly Val Gly Ile Thr 20 25 30 Ile Phe Gly Val Pro Tyr Tyr Trp Gly Gln Gly 35 40 <210> 8637 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8637 agagacaaca gcaaaaactc cctgtatctg caaatgaaca gtctgacaac tgaggactcc 60 gccttgtatt actgttcaaa aggagtaggt ataacgattt ttggagtgcc ttactactgg 120 ggccaggga 129 <210> 8638 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8638 Arg Asp Asn Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Thr 1 5 10 15 Thr Glu Asp Ser Ala Leu Tyr Tyr Cys Ser Lys Gly Val Gly Ile Thr 20 25 30 Ile Phe Gly Val Pro Tyr Tyr Trp Gly Gln Gly 35 40 <210> 8639 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8639 Cys Ala Arg Asp Gly Pro Pro Asp Ser Tyr Phe Asp Tyr Trp 1 5 10 <210> 8640 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8640 attaccgcgg acaaatccac gagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagagat ggccccccgg actcatactt tgactactgg 120 ggccaggga 129 <210> 8641 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8641 Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Gly Pro 20 25 30 Pro Asp Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8642 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8642 attaccgcgc acaaatccac gagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagagat ggccccccgg actcatactt tgactactgg 120 ggccaggga 129 <210> 8643 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8643 Ile Thr Ala His Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Gly Pro 20 25 30 Pro Asp Ser Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8644 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8644 Cys Ala Lys Ile Tyr Asn Tyr Gly Tyr Phe Asp Tyr Trp 1 5 10 <210> 8645 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8645 accatctcca tatataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa atctacaact atggttactt tgactactgg 120 ggccaggga 129 <210> 8646 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8646 Thr Ile Ser Ile Tyr Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ile Tyr 20 25 30 Asn Tyr Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8647 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8647 accatctcca gagataattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa atctacaact atggttactt tgactactgg 120 ggccaggga 129 <210> 8648 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8648 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ile Tyr 20 25 30 Asn Tyr Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8649 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8649 Cys Ala Arg Asp Arg Gly Ser Ser Trp Ile Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 8650 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8650 tgggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agatcgaggc agcagctgga tatactactt tgactactgg 120 ggccaggga 129 <210> 8651 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8651 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Gly Ser Ser 20 25 30 Trp Ile Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8652 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8652 agggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag agatcgaggc agcagctgga tatactactt tgactactgg 120 ggccaggga 129 <210> 8653 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8653 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Gly Ser Ser 20 25 30 Trp Ile Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8654 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8654 Cys Ala Arg Tyr Tyr Tyr Asp Ser Ser Gly Tyr Tyr Gly Asp Leu Leu 1 5 10 15 Glu Thr Pro Tyr Tyr Phe Asp Tyr Trp 20 25 <210> 8655 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8655 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagatattac 60 tatgatagta gtggttatta cggggacctg ttggagaccc cttactactt tgactactgg 120 ggccaggga 129 <210> 8656 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8656 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Tyr Tyr Tyr Asp Ser Ser Gly Tyr Tyr Gly Asp Leu Leu Glu 20 25 30 Thr Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8657 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8657 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagatattac 60 tatgatagta gtggttatta cggggacctg ttggagaccc cttactactt tgactactgg 120 ggccaggga 129 <210> 8658 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8658 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Tyr Tyr Tyr Asp Ser Ser Gly Tyr Tyr Gly Asp Leu Leu Glu 20 25 30 Thr Pro Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8659 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8659 Cys Ala Arg Asp Trp Phe Tyr Gly Asp Ser Arg Pro Asp Tyr Tyr Tyr 1 5 10 15 Tyr Tyr Gly Met Asp Val Trp 20 <210> 8660 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8660 gcctacatgg agctgagcag cctgagatct ggggacacgg ccgtgtatta ctgtgcgaga 60 gattggttct acggtgactc acgtcctgat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8661 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8661 Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Gly Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Asp Trp Phe Tyr Gly Asp Ser Arg Pro Asp Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8662 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8662 gcctacatgg agctgagcag cctgagatct gaggacacgg ccgtgtatta ctgtgcgaga 60 gattggttct acggtgactc acgtcctgat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8663 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8663 Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Asp Trp Phe Tyr Gly Asp Ser Arg Pro Asp Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8664 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8664 Cys Ala Arg Val Arg Phe His Trp Asn Tyr Ala Leu Phe Asp Ser Trp 1 5 10 15 <210> 8665 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8665 ttagacacgt ccaacaacca ggtctccctg aacttgaggt ctgtgaccgc cgcggacacg 60 gccgtatatt tctgtgcgag agtaaggttt cactggaact acgccctttt tgactcctgg 120 ggccaggga 129 <210> 8666 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8666 Leu Asp Thr Ser Asn Asn Gln Val Ser Leu Asn Leu Arg Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Phe Cys Ala Arg Val Arg Phe His Trp 20 25 30 Asn Tyr Ala Leu Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 8667 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8667 atagacacgt ccaagaacca ggtctccctg aacttgaggt ctgtgaccgc cgcggacacg 60 gccgtatatt tctgtgcgag agtaaggttt cactggaact acgccctttt tgactcctgg 120 ggccaggga 129 <210> 8668 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8668 Ile Asp Thr Ser Lys Asn Gln Val Ser Leu Asn Leu Arg Ser Val Thr 1 5 10 15 Ala Ala Asp Thr Ala Val Tyr Phe Cys Ala Arg Val Arg Phe His Trp 20 25 30 Asn Tyr Ala Leu Phe Asp Ser Trp Gly Gln Gly 35 40 <210> 8669 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8669 Cys Ala Lys Ser Gly Gln Leu Arg Ser Arg Asp Phe Asp Leu Trp 1 5 10 15 <210> 8670 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8670 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaatcaggc cagctgcgat cgagggactt cgatctctgg 120 ggtcgtggc 129 <210> 8671 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8671 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ser Gly Gln Leu 20 25 30 Arg Ser Arg Asp Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8672 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8672 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaatcaggc cagctgcgat cgagggactt cgatctctgg 120 ggccgtggc 129 <210> 8673 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8673 Cys Ala Lys Ala Ser Asp Tyr Gly Asp Tyr Leu Phe Asp Tyr Trp 1 5 10 15 <210> 8674 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8674 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaagcctcc gactacggtg actacctctt tgactactgg 120 ggccaggga 129 <210> 8675 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8675 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Ser Asp Tyr 20 25 30 Gly Asp Tyr Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8676 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8676 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaagcctcc gactacggtg actacctctt tgactactgg 120 gaccaggga 129 <210> 8677 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8677 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Ala Ser Asp Tyr 20 25 30 Gly Asp Tyr Leu Phe Asp Tyr Trp Asp Gln Gly 35 40 <210> 8678 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8678 Cys Ala Lys Gly Arg Ser Gly Ser Tyr Gln Thr Leu Phe Glu Tyr Trp 1 5 10 15 <210> 8679 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8679 agagacaatt ccaagaatag gctgtatctt caaatggaca gcctgagagt cgaggacacg 60 gccatgtatt actgtgcgaa aggaagaagc gggagctacc aaaccctctt tgaatactgg 120 ggccaggga 129 <210> 8680 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8680 Arg Asp Asn Ser Lys Asn Arg Leu Tyr Leu Gln Met Asp Ser Leu Arg 1 5 10 15 Val Glu Asp Thr Ala Met Tyr Tyr Cys Ala Lys Gly Arg Ser Gly Ser 20 25 30 Tyr Gln Thr Leu Phe Glu Tyr Trp Gly Gln Gly 35 40 <210> 8681 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8681 agagacaatt ccaagaatag gctgtatctt caaatggaca gcctgagagt cgaggacacg 60 gccatgcatt actgtgcgaa aggaagaagc gggagctacc aaaccctctt tgaatactgg 120 ggccaggga 129 <210> 8682 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8682 Arg Asp Asn Ser Lys Asn Arg Leu Tyr Leu Gln Met Asp Ser Leu Arg 1 5 10 15 Val Glu Asp Thr Ala Met His Tyr Cys Ala Lys Gly Arg Ser Gly Ser 20 25 30 Tyr Gln Thr Leu Phe Glu Tyr Trp Gly Gln Gly 35 40 <210> 8683 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8683 Cys Ala Lys Gly Gln Arg Phe Leu Glu Trp Leu Pro Ile Pro Pro Phe 1 5 10 15 Ala Asp Trp <210> 8684 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8684 tccaagaaca tggtttatct gcacatgaac agcctgagag ccgacgacac ggccgtatat 60 tattgtgcga aagggcaacg atttttggag tggttgccca tacccccgtt tgcagactgg 120 ggccaggga 129 <210> 8685 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8685 Ser Lys Asn Met Val Tyr Leu His Met Asn Ser Leu Arg Ala Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gln Arg Phe Leu Glu Trp Leu 20 25 30 Pro Ile Pro Pro Phe Ala Asp Trp Gly Gln Gly 35 40 <210> 8686 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8686 tccaagaaca cgctgtatct gcaaatgaac agcctgagag ccgacgacac ggccgtatat 60 tattgtgcga aagggcaacg atttttggag tggttgccca tacccccgtt tgcagactgg 120 ggccaggga 129 <210> 8687 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8687 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Lys Gly Gln Arg Phe Leu Glu Trp Leu 20 25 30 Pro Ile Pro Pro Phe Ala Asp Trp Gly Gln Gly 35 40 <210> 8688 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8688 Cys Ala Ser Gly His Gly Ile Ala Val Ala Gly Thr Met Asp Ala Phe 1 5 10 15 Asp Ile Trp <210> 8689 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8689 tccaagaaca cgctgtatct tcaaatgaac agcctgagag ccgaggacac ggccgtgtat 60 tactgtgcga gcggccatgg tatagcagtg gctggtacca tggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8690 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8690 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Ser Gly His Gly Ile Ala Val Ala Gly 20 25 30 Thr Met Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8691 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8691 tccaagaaca agatgtatct tcaaatgaac agcctgagag ccgaggacac ggccgtgtat 60 tactgtgcga gcggccatgg tatagcagtg gctggtacca tggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8692 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8692 Ser Lys Asn Lys Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Ser Gly His Gly Ile Ala Val Ala Gly 20 25 30 Thr Met Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8693 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8693 Cys Ala Arg His Ile Asp Ala Leu Ala Ala Tyr Leu Ser Tyr Tyr Tyr 1 5 10 15 Tyr Gly Met Asp Val Trp 20 <210> 8694 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8694 acggcatatt tgcagatcag cagcctaaag gctgaggaca ctgccgtgta ttactgtgcg 60 agacacatcg acgctttagc agcttatctt tcttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8695 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8695 Thr Ala Tyr Leu Gln Ile Ser Ser Leu Lys Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg His Ile Asp Ala Leu Ala Ala Tyr Leu Ser Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8696 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8696 acggcatatc tgcagatcag cagcctaaag gctgaggaca ctgccgtgta ttactgtgcg 60 agacacatcg acgctttagc agcttatctt tcttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8697 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8697 Cys Thr Thr Leu Asp Ile Ala His Tyr Tyr Tyr Tyr Tyr Tyr Gly Met 1 5 10 15 Asp Val Trp <210> 8698 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8698 tcaaaaaaca cgctgtatct gcaaatgaac agcctgaaaa ccgaggacac agccgtgtat 60 tactgtacca cacttgacat agctcattat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8699 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8699 Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Thr Leu Asp Ile Ala His Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8700 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8700 ttcaaaaaca cgctgtatct gcaaatgaac agcctgaaaa ccgaggacac agccgtgtat 60 tactgtacca cacttgacat agctcattat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8701 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8701 Phe Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Thr Leu Asp Ile Ala His Tyr Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8702 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8702 Cys Ala Lys Asp Pro Arg Gln Asn Tyr Gly Pro Thr Tyr Phe Asp Leu 1 5 10 15 Trp <210> 8703 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8703 gatgattcca agaacacggt gtatttgcaa atgaacagcc tgagagccga ggacacggcc 60 gtctattact gtgcgaaaga tccccgccaa aactacggac ctacgtactt cgatctctgg 120 ggccgtggc 129 <210> 8704 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8704 Asp Asp Ser Lys Asn Thr Val Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Arg Gln Asn Tyr 20 25 30 Gly Pro Thr Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8705 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8705 gacaattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtctattact gtgcgaaaga tccccgccaa aactacggac ctacgtactt cgatctctgg 120 ggccgtggc 129 <210> 8706 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8706 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Pro Arg Gln Asn Tyr 20 25 30 Gly Pro Thr Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8707 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8707 Cys Ala His Ala Tyr Cys Ser Thr Thr Ser Cys Asp Pro Tyr Tyr Tyr 1 5 10 15 Tyr Asp Met Asp Val Trp 20 <210> 8708 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8708 caggtggtcc ttacagtgac caacatggac cctgtggaca cagccacata ttactgtgca 60 cacgcgtatt gtagtaccac cagctgcgac ccctactact actacgatat ggacgtctgg 120 ggccaaggg 129 <210> 8709 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8709 Gln Val Val Leu Thr Val Thr Asn Met Asp Pro Val Asp Thr Ala Thr 1 5 10 15 Tyr Tyr Cys Ala His Ala Tyr Cys Ser Thr Thr Ser Cys Asp Pro Tyr 20 25 30 Tyr Tyr Tyr Asp Met Asp Val Trp Gly Gln Gly 35 40 <210> 8710 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8710 caggtggtcc ctacagtgac caacatggac cctgtggaca cagccgcata ttactgtgca 60 cacgcgtatt gtagtaccac cagctgcgac ccctactact actacgatat ggacgtctgg 120 ggccaaggg 129 <210> 8711 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8711 Gln Val Val Pro Thr Val Thr Asn Met Asp Pro Val Asp Thr Ala Ala 1 5 10 15 Tyr Tyr Cys Ala His Ala Tyr Cys Ser Thr Thr Ser Cys Asp Pro Tyr 20 25 30 Tyr Tyr Tyr Asp Met Asp Val Trp Gly Gln Gly 35 40 <210> 8712 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8712 Cys Ala His Arg Pro Ser Leu Gln Trp Leu Asp Trp Trp Phe Asp Pro 1 5 10 15 Trp <210> 8713 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8713 gacacctcca aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacag acccagcctt cagtggctgg actggtggtt cgacccctgg 120 ggccaggga 129 <210> 8714 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8714 Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Pro Ser Leu Gln Trp 20 25 30 Leu Asp Trp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8715 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8715 ggacacctcc aaaaccaggt ggtccttaca atgaccaaca tggaccctgt ggacacagcc 60 acatattact gtgcacacag acccagcctt cagtggctgg actggtggtt cgacccctgg 120 ggccaggga 129 <210> 8716 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8716 Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro 1 5 10 15 Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Arg Pro Ser Leu Gln Trp 20 25 30 Leu Asp Trp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8717 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8717 Cys Ala Arg Thr Trp Arg Arg Asp Gly Tyr Arg Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 8718 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8718 tgggacacgt ccattagcac agcctacatg gagttgagca ggctgagatc agacgacacg 60 gccgtgtatt attgtgcgag gacatggcgt agagatggct acagatactt tgactactgg 120 ggccaggga 129 <210> 8719 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8719 Trp Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Thr Trp Arg Arg Asp 20 25 30 Gly Tyr Arg Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8720 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8720 agggacacgt ccattagcac agcctacatg gagttgagca ggctgagatc agacgacacg 60 gccgtgtatt attgtgcgag gacatggcgt agagatggct acagatactt tgactactgg 120 ggccaggga 129 <210> 8721 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8721 Arg Asp Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Arg Leu Arg 1 5 10 15 Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Thr Trp Arg Arg Asp 20 25 30 Gly Tyr Arg Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8722 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8722 Cys Thr Arg Asp Met Leu Thr Ser Val Ile Arg Thr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 8723 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8723 aagaacacgg tgtatctgca aatgaacagt ctgggagccg aggacacggc tacttattac 60 tgtacaagag atatgctgac ttcggtgatt aggacatact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8724 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8724 Lys Asn Thr Val Tyr Leu Gln Met Asn Ser Leu Gly Ala Glu Asp Thr 1 5 10 15 Ala Thr Tyr Tyr Cys Thr Arg Asp Met Leu Thr Ser Val Ile Arg Thr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8725 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8725 aagaacacgg tgtatctgca aatgaacagt ctgagagccg aggacacggc tacttattac 60 tgtacaagag atatgctgac ttcggtgatt aggacatact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8726 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8726 Lys Asn Thr Val Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Thr Tyr Tyr Cys Thr Arg Asp Met Leu Thr Ser Val Ile Arg Thr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8727 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8727 Cys Ala Arg Asp Tyr Tyr Tyr Gly Ser Gly Ser Tyr Tyr Asn Gly Asp 1 5 10 15 Asn Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 8728 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8728 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagattat 60 tactatggtt cggggagtta ttataacgga gataactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8729 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8729 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Asp Tyr Tyr Tyr Gly Ser Gly Ser Tyr Tyr Asn Gly Asp Asn 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8730 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8730 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagagattat 60 tactatggtt cggggagcta ttataacgga gataactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8731 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8731 Cys Ala Arg Val Ile Gly Lys Asp Ala Thr Gly Asp Tyr Trp 1 5 10 <210> 8732 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8732 atctccagag acaatgccaa gaactcactg tatctgcaaa tgaacagcct gagagacgag 60 gacacggctg tgtattactg tgcgagagtg atagggaagg atgctacggg agactactgg 120 ggccaggga 129 <210> 8733 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8733 Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Ile Gly 20 25 30 Lys Asp Ala Thr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 8734 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8734 atctccagac acaatcccaa gaactcactg tatctgcaaa tgaacagcct gagagacgag 60 gacacggctg tgtattactg tgcgagagtg atagggaagg atgctacggg agactactgg 120 ggccaggga 129 <210> 8735 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8735 Ile Ser Arg His Asn Pro Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Ile Gly 20 25 30 Lys Asp Ala Thr Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 8736 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8736 Cys Ala Arg Gly Pro Glu Asp Tyr Gly Asp Ser Tyr Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 8737 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8737 tgcacagcct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagaggcc cggaggacta cggtgactct tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8738 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8738 Cys Thr Ala Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Pro Glu Asp Tyr Gly Asp Ser Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8739 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8739 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagaggcc cggaggacta cggtgactct tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8740 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8740 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Gly Pro Glu Asp Tyr Gly Asp Ser Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8741 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8741 Cys Ala His Ser Arg Ser Arg Tyr Ser Ser Gly Trp Tyr Tyr Phe Asp 1 5 10 15 Tyr Trp <210> 8742 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8742 acctccaaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacagtcg tagtaggtat agcagtggct ggtactactt tgactactgg 120 ggccaggga 129 <210> 8743 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8743 Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Arg Ser Arg Tyr Ser Ser 20 25 30 Gly Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8744 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8744 cacctccaaa accaggtggt ccttacaatg accaacatgg accctgtgga cacagccaca 60 tattactgtg cacacagtcg tagtaggtat agcagtggct ggtactactt tgactactgg 120 ggccaggga 129 <210> 8745 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8745 His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val 1 5 10 15 Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Arg Ser Arg Tyr Ser Ser 20 25 30 Gly Trp Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8746 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8746 Cys Ala Lys Gly Leu Arg Trp Gln Lys Thr Asn Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 8747 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8747 agatataatt ccaacaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa aggtctacgg tggcaaaaaa caaactactt tgactactgg 120 ggccaggga 129 <210> 8748 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8748 Arg Tyr Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Arg Trp Gln 20 25 30 Lys Thr Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8749 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8749 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa aggtctacgg tggcaaaaaa caaactactt tgactactgg 120 ggccaggga 129 <210> 8750 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8750 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Leu Arg Trp Gln 20 25 30 Lys Thr Asn Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8751 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8751 Cys Ile Arg Gly Leu Arg Gly Asp Ser Ala Tyr Asp Tyr Gly Ala Phe 1 5 10 15 Trp <210> 8752 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8752 tatgagtcaa agaactcact gtatctccaa atgaacagcc taaaaagcga ggacacggcc 60 atatactact gtattagggg ccttcgcggg gatagtgcct acgattatgg ggccttctgg 120 ggccaggga 129 <210> 8753 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8753 Tyr Glu Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Lys Ser 1 5 10 15 Glu Asp Thr Ala Ile Tyr Tyr Cys Ile Arg Gly Leu Arg Gly Asp Ser 20 25 30 Ala Tyr Asp Tyr Gly Ala Phe Trp Gly Gln Gly 35 40 <210> 8754 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8754 gatgagtcaa agaactcact gtatctccaa atgaacagcc taaaaagcga ggacacggcc 60 atatactact gtattagggg ccttcgcggg gatagtgcct acgattatgg ggccttctgg 120 ggccaggga 129 <210> 8755 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8755 Asp Glu Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Lys Ser 1 5 10 15 Glu Asp Thr Ala Ile Tyr Tyr Cys Ile Arg Gly Leu Arg Gly Asp Ser 20 25 30 Ala Tyr Asp Tyr Gly Ala Phe Trp Gly Gln Gly 35 40 <210> 8756 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8756 Cys Ala Arg Asp Leu Val Pro Tyr Tyr Gly Pro Thr Gly Gly Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 8757 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8757 tgcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatc tagtccctta ctatggtccc accgggggct actatggtat ggacgtctgg 120 ggccaaggg 129 <210> 8758 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8758 Cys Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Leu Val Pro Tyr Tyr Gly Pro Thr Gly 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8759 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8759 agcacagcct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagatc tagtccctta ctatggtccc accgggggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8760 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8760 Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Asp Leu Val Pro Tyr Tyr Gly Pro Thr Gly 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8761 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8761 Cys Ala Arg Glu Gly Tyr Arg Asp Tyr Leu Trp Tyr Phe Asp Leu Trp 1 5 10 15 <210> 8762 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8762 tgggacaacg ccaagaactc tctggctctg caaatggaca gcctgagagg cgaggacgcg 60 ggtctatatt actgtgcgag agagggctac cgtgactacc tttggtactt cgatctctgg 120 ggccgtggc 129 <210> 8763 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8763 Trp Asp Asn Ala Lys Asn Ser Leu Ala Leu Gln Met Asp Ser Leu Arg 1 5 10 15 Gly Glu Asp Ala Gly Leu Tyr Tyr Cys Ala Arg Glu Gly Tyr Arg Asp 20 25 30 Tyr Leu Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8764 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8764 agggacaacg ccaagaactc actggctctg caaatggaca gcctgagagg cgaggacgcg 60 ggtctatatt actgtgcgag agagggctac cgtgactacc tttggtactt cgatctctgg 120 ggccgtggc 129 <210> 8765 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8765 Arg Asp Asn Ala Lys Asn Ser Leu Ala Leu Gln Met Asp Ser Leu Arg 1 5 10 15 Gly Glu Asp Ala Gly Leu Tyr Tyr Cys Ala Arg Glu Gly Tyr Arg Asp 20 25 30 Tyr Leu Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8766 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8766 Cys Ala Arg Gly Leu Gly Asp Ile Val Val Val Pro Ala Ala Met Arg 1 5 10 15 Pro Thr Leu Phe Asp Tyr Trp 20 <210> 8767 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8767 ttctccctga agctgagctc tgtgactgcc gcggacacgg ccgtgtatta ctgtgcgaga 60 ggtttggggg atattgtagt agtaccagct gctatgcgcc cgaccctttt tgactactgg 120 ggccaggga 129 <210> 8768 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8768 Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Gly Leu Gly Asp Ile Val Val Val Pro Ala Ala Met 20 25 30 Arg Pro Thr Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8769 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8769 ttctccctga agctgagctc tgcgactgcc gcggacacgg ccgtgtatta ctgtgcgaga 60 ggtttggggg atattgtagt agtaccagct gctatgcgcc cgaccctttt tgactactgg 120 ggccaggga 129 <210> 8770 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8770 Phe Ser Leu Lys Leu Ser Ser Ala Thr Ala Ala Asp Thr Ala Val Tyr 1 5 10 15 Tyr Cys Ala Arg Gly Leu Gly Asp Ile Val Val Val Pro Ala Ala Met 20 25 30 Arg Pro Thr Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8771 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8771 Cys Ala Arg His Ile Gly Tyr Gly Asn Asn Trp Phe Asp Pro Trp 1 5 10 15 <210> 8772 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8772 tcagtagaca cgtccaagaa ccagttctcc ctgaacttga ggtctgtgac cgccgcagac 60 acggccatat attattgtgc gagacatata ggctacggga acaactggtt cgacccctgg 120 ggccaggga 129 <210> 8773 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8773 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Asn Leu Arg Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Ile Tyr Tyr Cys Ala Arg His Ile Gly Tyr 20 25 30 Gly Asn Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8774 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8774 tcagtagaca cgtccaagaa ccaggtctcc ctgaacttga ggtctgtgac cgccgcagac 60 acggccgtgt attactgtgc gagacatata ggctacggga acaactggtt cgacccctgg 120 ggccaggga 129 <210> 8775 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8775 Ser Val Asp Thr Ser Lys Asn Gln Val Ser Leu Asn Leu Arg Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg His Ile Gly Tyr 20 25 30 Gly Asn Asn Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8776 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8776 Cys Ala Lys Leu Pro Thr Ser Gly Ile Arg Gly Gln Asp Asn Trp Leu 1 5 10 15 Asp Pro Trp <210> 8777 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8777 tccaagaaca tgttgtatct gcaaatgacc agcctgagag tcgaggacac ggccatatat 60 ttctgtgcga aactgccgac ttcgggtata cgtggacaag ataactggct cgacccctgg 120 ggccagggc 129 <210> 8778 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8778 Ser Lys Asn Met Leu Tyr Leu Gln Met Thr Ser Leu Arg Val Glu Asp 1 5 10 15 Thr Ala Ile Tyr Phe Cys Ala Lys Leu Pro Thr Ser Gly Ile Arg Gly 20 25 30 Gln Asp Asn Trp Leu Asp Pro Trp Gly Gln Gly 35 40 <210> 8779 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8779 tccaagaaca tgttgtatct gcaaatgacc agcctgagag ccgaggacac ggccatatat 60 ttctgtgcga aactgccgac ttcgggtata cgtggacaag ataactggct cgacccctgg 120 ggccagggc 129 <210> 8780 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8780 Ser Lys Asn Met Leu Tyr Leu Gln Met Thr Ser Leu Arg Ala Glu Asp 1 5 10 15 Thr Ala Ile Tyr Phe Cys Ala Lys Leu Pro Thr Ser Gly Ile Arg Gly 20 25 30 Gln Asp Asn Trp Leu Asp Pro Trp Gly Gln Gly 35 40 <210> 8781 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8781 Cys Ala Arg Glu Gly Trp Glu His Met Asp Val Trp 1 5 10 <210> 8782 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8782 atcaccgtga cgatggacac atccgcgagc acaggctata tggagctgag gagcctgaga 60 gcagacgaca cggccgtata ttattgtgcg agagaggggt gggagcatat ggacgtctgg 120 ggccaaggg 129 <210> 8783 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8783 Ile Thr Val Thr Met Asp Thr Ser Ala Ser Thr Gly Tyr Met Glu Leu 1 5 10 15 Arg Ser Leu Arg Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu 20 25 30 Gly Trp Glu His Met Asp Val Trp Gly Gln Gly 35 40 <210> 8784 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8784 atcaccgtga cgatgcacac atccgcgagc acaggctata tggagctgag gagcctgaga 60 gcagacgaca cggccgtata ttattgtgcg agagaggggt gggagcatat ggacgtctgg 120 ggccaaggg 129 <210> 8785 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8785 Ile Thr Val Thr Met His Thr Ser Ala Ser Thr Gly Tyr Met Glu Leu 1 5 10 15 Arg Ser Leu Arg Ala Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu 20 25 30 Gly Trp Glu His Met Asp Val Trp Gly Gln Gly 35 40 <210> 8786 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8786 Cys Ala Asn Glu Arg Gly Arg Leu Phe Asp Tyr Trp 1 5 10 <210> 8787 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8787 ttcaccatct ccagagacaa cggcaaaaac tccctgtatc tgcaaatgag cagtctgaaa 60 actgaggaca ccgccttgta ttactgtgca aacgaacggg ggcgactatt tgactactgg 120 ggccaggga 129 <210> 8788 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8788 Phe Thr Ile Ser Arg Asp Asn Gly Lys Asn Ser Leu Tyr Leu Gln Met 1 5 10 15 Ser Ser Leu Lys Thr Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Asn Glu 20 25 30 Arg Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8789 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8789 ttcaccatct ccagagacaa cagcaaaaac tccctgtatc tgcaaatgaa cagtctgaaa 60 actgaggaca ccgccttgta ttactgtgca aacgaacggg ggcgactatt tgactactgg 120 ggccaggga 129 <210> 8790 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8790 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Ser Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Lys Thr Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Asn Glu 20 25 30 Arg Gly Arg Leu Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8791 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8791 Cys Thr Thr Thr Tyr Tyr Asp Ile Leu Thr Gly Tyr Phe Leu Asp Arg 1 5 10 15 Leu Val Phe Tyr Trp 20 <210> 8792 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8792 aacacgctgt atctgcaaat gaacagcctg aaaaccgagg acacagccgt gtattactgt 60 accacaacct attacgatat tttgactggt tattttctgg accgcctcgt cttctactgg 120 ggccaggga 129 <210> 8793 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8793 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Thr Thr Thr Tyr Tyr Asp Ile Leu Thr Gly Tyr Phe 20 25 30 Leu Asp Arg Leu Val Phe Tyr Trp Gly Gln Gly 35 40 <210> 8794 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8794 aacacgctgt atctgcaaat gaacagcctg aaaaccgagg acacagccgt gtattactgt 60 accacaacct attacgatat tttgactggc tattttctgg accgcctcgt cttctactgg 120 ggccaggga 129 <210> 8795 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8795 Cys Ala Arg Gly Gly Arg Arg Trp Leu Gln Phe Arg Gly Gly Phe Asp 1 5 10 15 Tyr Trp <210> 8796 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8796 tcgtccaaga accagttctc cctgaagctg agctctgtga ccgccgcgga cacggctgtg 60 tattactgtg cgagaggagg gaggagatgg ctacaattta gggggggctt tgactactgg 120 ggccaggga 129 <210> 8797 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8797 Ser Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Arg Arg Trp Leu Gln 20 25 30 Phe Arg Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8798 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8798 acgtccaaga accagttctc cctgaagctg agctctgtga ccgccgcgga cacggctgtg 60 tattactgtg cgagaggagg gaggagatgg ctacaattta gggggggctt tgactactgg 120 ggccaggga 129 <210> 8799 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8799 Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Arg Arg Trp Leu Gln 20 25 30 Phe Arg Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8800 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8800 Cys Ala Arg Asp Arg Glu Val Ala Gly Thr Glu Ala Asn Tyr Phe Lys 1 5 10 15 Asp Trp <210> 8801 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8801 acgtccacga ggacagtcta catggaactg agcagcctgg catctgatga cacggccgtg 60 tactactgtg cgagagaccg ggaagtggct ggtacggagg cgaactactt taaagactgg 120 ggccaggga 129 <210> 8802 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8802 Thr Ser Thr Arg Thr Val Tyr Met Glu Leu Ser Ser Leu Ala Ser Asp 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Glu Val Ala Gly Thr 20 25 30 Glu Ala Asn Tyr Phe Lys Asp Trp Gly Gln Gly 35 40 <210> 8803 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8803 acgtccacga ggacagtcta catggaactg agcagcctga catctgatga cacggccgtg 60 tactactgtg cgagagaccg ggaagtggct ggtacggagg cgaactactt taaagactgg 120 ggccaggga 129 <210> 8804 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8804 Thr Ser Thr Arg Thr Val Tyr Met Glu Leu Ser Ser Leu Thr Ser Asp 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Arg Glu Val Ala Gly Thr 20 25 30 Glu Ala Asn Tyr Phe Lys Asp Trp Gly Gln Gly 35 40 <210> 8805 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8805 Cys Ala Arg Asp Pro Tyr Arg Gly Gly Met Asp Val Trp 1 5 10 <210> 8806 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8806 tccatctcca tagacaatgc caagaactca ctgtatctgc aaatgaacag cctgagagac 60 gaggacacgg ctgtgtatta ctgtgcgaga gatccctacc gcggcggtat ggacgtctgg 120 ggccaaggg 129 <210> 8807 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8807 Ser Ile Ser Ile Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro 20 25 30 Tyr Arg Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8808 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8808 accatctcca gagacaatgc caagaactca ctgtatctgc aaatgaacag cctgagagac 60 gaggacacgg ctgtgtatta ctgtgcgaga gatccctacc gcggcggtat ggacgtctgg 120 ggccaaggg 129 <210> 8809 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8809 Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Asp Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Pro 20 25 30 Tyr Arg Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8810 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8810 Cys Thr Arg Val Arg Arg Gly Ser Gly Val Ala Pro Tyr Ser Ser Ser 1 5 10 15 Trp Gly Arg Tyr Tyr Phe Asp Tyr Trp 20 25 <210> 8811 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8811 ctgcaaatga acagcctgaa aaccgaggac acagccgtgt attactgtac tagagttaga 60 agagggtcgg gggtggcgcc gtatagcagc agctggggac ggtactactt tgactactgg 120 ggccaggga 129 <210> 8812 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8812 Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Thr Arg Val Arg Arg Gly Ser Gly Val Ala Pro Tyr Ser Ser Ser Trp 20 25 30 Gly Arg Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8813 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8813 ctgaaaatga acagcctgaa aaccgaggac acagccgtgt attactgtac tagagttaga 60 agagggtcgg gggtggcgcc gtatagcagc agctggggac ggtactactt tgactactgg 120 ggccaggga 129 <210> 8814 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8814 Leu Lys Met Asn Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Thr Arg Val Arg Arg Gly Ser Gly Val Ala Pro Tyr Ser Ser Ser Trp 20 25 30 Gly Arg Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8815 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8815 Cys Ala Lys Asp Tyr Ser Lys Tyr Gly Asp Tyr Gly Gly Tyr Phe Asp 1 5 10 15 Leu Trp <210> 8816 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8816 aacgccaaga actccctgta tctgcaaatg aacagtctga gagctgagga cacggccttg 60 tattactgtg caaaagatta ttcgaagtac ggtgactacg ggggatactt cgatctctgg 120 ggccgtggc 129 <210> 8817 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8817 Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Tyr Ser Lys Tyr Gly Asp 20 25 30 Tyr Gly Gly Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8818 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8818 aacgccaaga actccctgta tctgcaaatg aacagtctga gagctgagga cacggccttg 60 cattactgtg caaaagatta ttcgaagtac ggtgactacg ggggatactt cgacctctgg 120 ggccgtggc 129 <210> 8819 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8819 Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Leu His Tyr Cys Ala Lys Asp Tyr Ser Lys Tyr Gly Asp 20 25 30 Tyr Gly Gly Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 8820 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8820 Cys Ala His Gly Asp Asp Ile Leu Thr Gly Tyr Ala Phe Asp Ile Trp 1 5 10 15 <210> 8821 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8821 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cggtgacgat attttgactg gttatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8822 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8822 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Asp Asp Ile Leu 20 25 30 Thr Gly Tyr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8823 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8823 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cggtgacgat attttgactg gttatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8824 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8824 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Gly Asp Asp Ile Leu 20 25 30 Thr Gly Tyr Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8825 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8825 Cys Ala Arg Asp Pro His Ser Thr Gly Val Gly Trp Tyr Gly Gly Ala 1 5 10 15 Tyr Phe Asp Tyr Trp 20 <210> 8826 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8826 aactccctgt atctgcaaat gaacagtctg agagccgagg acacggcctt gtattactgt 60 gcgagagacc cccactccac cggggtcggc tggtacgggg gggcttactt tgactactgg 120 ggccaggga 129 <210> 8827 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8827 Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Leu Tyr Tyr Cys Ala Arg Asp Pro His Ser Thr Gly Val Gly Trp Tyr 20 25 30 Gly Gly Ala Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8828 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8828 tactccctgt atctgcaaat gaacagtctg agagccgagg acacggcctt gtattactgt 60 gcgagagacc cccactccac cggggtcggc tggtacgggg gggcttactt tgactactgg 120 ggccaggga 129 <210> 8829 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8829 Tyr Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Leu Tyr Tyr Cys Ala Arg Asp Pro His Ser Thr Gly Val Gly Trp Tyr 20 25 30 Gly Gly Ala Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8830 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8830 Cys Ala Lys Glu Tyr Ser Ser Ser Trp Phe Asp Pro Trp 1 5 10 <210> 8831 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8831 tacatctcca gagacaacgc caagaactcc ctgtatctgc aaatgaacag tctgagagct 60 gaggacacgg ccttttatta ctgtgcaaaa gaatatagca gctcctggtt cgacccctgg 120 ggccaggga 129 <210> 8832 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8832 Tyr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Phe Tyr Tyr Cys Ala Lys Glu Tyr 20 25 30 Ser Ser Ser Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8833 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8833 accatctcca gagacaacgc caagaactcc ctgtatctgc aaatgaacag tctgagagct 60 gaggacacgg ccttttatta ctgtgcaaaa gaatatagca gctcctggtt cgacccctgg 120 ggccaggga 129 <210> 8834 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8834 Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Phe Tyr Tyr Cys Ala Lys Glu Tyr 20 25 30 Ser Ser Ser Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8835 <211> 26 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8835 Cys Ala Arg Asp Ala Arg Gly Val Arg Trp Tyr Thr Tyr Tyr Tyr Gly 1 5 10 15 Ser Gly Ser Ser Tyr Gly Met Asp Val Trp 20 25 <210> 8836 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8836 caaatgaaca gtctgagagc cgaggacgcg gccttgtatt actgtgcgag agatgccagg 60 ggtgtcaggt ggtacacgta ttactatggt tcggggagtt cttacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8837 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8837 Gln Met Asn Ser Leu Arg Ala Glu Asp Ala Ala Leu Tyr Tyr Cys Ala 1 5 10 15 Arg Asp Ala Arg Gly Val Arg Trp Tyr Thr Tyr Tyr Tyr Gly Ser Gly 20 25 30 Ser Ser Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8838 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8838 caaatgaaca gtctgagagc cgaggacacg gccttgtatt actgtgcgag agatgccagg 60 ggtgtcagat ggtacacgta ttactatggt tcggggagtt cttacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8839 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8839 Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala 1 5 10 15 Arg Asp Ala Arg Gly Val Arg Trp Tyr Thr Tyr Tyr Tyr Gly Ser Gly 20 25 30 Ser Ser Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8840 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8840 Cys Gly Arg Asp Ala Arg Ser Ser Gly Tyr Asn Gly Tyr Asp Leu Phe 1 5 10 15 Asp Ile Trp <210> 8841 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8841 tccatcagca cagccttcat ggaacttagc agtctaagat atgacgacac ggccgtatat 60 tactgtggga gagatgcacg gtctagtggc tacaatggat atgatttgtt tgatatctgg 120 ggccaaggg 129 <210> 8842 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8842 Ser Ile Ser Thr Ala Phe Met Glu Leu Ser Ser Leu Arg Tyr Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Gly Arg Asp Ala Arg Ser Ser Gly Tyr Asn 20 25 30 Gly Tyr Asp Leu Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8843 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8843 cccatcagca cagccttcat ggaacttagc agtctaagat atgacgacac ggccgtatat 60 tactgtggga gagatgcacg gtctagtggc tacaatggat atgatttgtt tgatatctgg 120 ggccaaggg 129 <210> 8844 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8844 Pro Ile Ser Thr Ala Phe Met Glu Leu Ser Ser Leu Arg Tyr Asp Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Gly Arg Asp Ala Arg Ser Ser Gly Tyr Asn 20 25 30 Gly Tyr Asp Leu Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8845 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8845 Cys Ala Arg Glu Trp Ile Thr Met Val Gln Gly Arg Asp Gly Met Asp 1 5 10 15 Val Trp <210> 8846 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8846 aacgccaaga acacgctgta tctgcaaatg aacagtctga gagccgaaga cacggctgtg 60 tatttctgtg caagagagtg gattactatg gttcaggggc gagacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8847 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8847 Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Phe Cys Ala Arg Glu Trp Ile Thr Met Val Gln 20 25 30 Gly Arg Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8848 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8848 aacgccaaga acacgctgta tctgcaaatg aacagtccga gagccgaaga cacggctgtg 60 tatttctgtg caagagagtg gattactatg gttcaggggc gagacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8849 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8849 Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Pro Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Phe Cys Ala Arg Glu Trp Ile Thr Met Val Gln 20 25 30 Gly Arg Asp Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8850 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8850 Cys Ala Arg Thr Thr Pro Phe Gly Trp Tyr Asp Tyr Trp 1 5 10 <210> 8851 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8851 tgtatctcaa tagatgattc aaagaactca ctgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtacta ctgtgctagg acgaccccct ttggctggta cgactactgg 120 ggccaggga 129 <210> 8852 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8852 Cys Ile Ser Ile Asp Asp Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Thr Thr 20 25 30 Pro Phe Gly Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 8853 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8853 agtatctcaa gagatgattc aaagaactca ctgtatctgc aaatgaacag cctgaaaacc 60 gaggacacgg ccgtgtacta ctgtgctagg acgaccccct ttggctggta cgactactgg 120 ggccaggga 129 <210> 8854 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8854 Ser Ile Ser Arg Asp Asp Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Lys Thr Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Thr Thr 20 25 30 Pro Phe Gly Trp Tyr Asp Tyr Trp Gly Gln Gly 35 40 <210> 8855 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8855 Cys Ala Lys Asp Tyr Glu Ala Ala Ala Gly Thr Trp 1 5 10 <210> 8856 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8856 ttcaccatct ccagatataa ttccaagaac gcgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagattacg aagcagcagc tggtacctgg 120 ggccaggga 129 <210> 8857 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8857 Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Ala Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp 20 25 30 Tyr Glu Ala Ala Ala Gly Thr Trp Gly Gln Gly 35 40 <210> 8858 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8858 ttcaccatct ccagagataa ttccaagaac gcgctgtatc tgcaaatgaa cagcctgaga 60 gccgaggaca cggccgtata ttactgtgcg aaagattacg aagcagcagc tggtacctgg 120 ggccaggga 129 <210> 8859 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8859 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Ala Leu Tyr Leu Gln Met 1 5 10 15 Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp 20 25 30 Tyr Glu Ala Ala Ala Gly Thr Trp Gly Gln Gly 35 40 <210> 8860 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8860 Cys Ala Arg Gly Gly Arg Gly Tyr Ser Ser Ser Trp Ser Leu Asp Tyr 1 5 10 15 Trp <210> 8861 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8861 gacacatcca agaaccagtt ctccctgcag ctgaactctg tgactcccga ggacacggct 60 gtgtattact gtgcaagagg gggtcggggg tatagcagca gctggtccct tgactactgg 120 ggccaggga 129 <210> 8862 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8862 Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser Val Thr Pro 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Arg Gly Tyr Ser 20 25 30 Ser Ser Trp Ser Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8863 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8863 gacacatcca agaaccagtt ctccctgcag ctgaactctg tgactcccga ggacacggct 60 gtgtattact gtgcaagagg ggggcggggg tatagcagca gctggtccct tgactactgg 120 ggccaggga 129 <210> 8864 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8864 Cys Ala Lys Asp Met Val Tyr Thr Ser Gly Gly Gly Ala Leu Asp Tyr 1 5 10 15 Trp <210> 8865 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8865 gacaacgtca agaactccct gtatctgcaa atgaacagtc tgagacctga ggacacggcc 60 ttatattact gtgcaaaaga tatggtgtat accagtggag ggggggctct tgactactgg 120 ggccaggga 129 <210> 8866 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8866 Asp Asn Val Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Pro 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Met Val Tyr Thr Ser 20 25 30 Gly Gly Gly Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8867 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8867 gacaacgtca acaactccct gtatctgcaa atgaacagtc tgagacctga ggacacggcc 60 ttatattact gtgcaaaaga tatggtgtat accagtggag ggggggctct tgactactgg 120 ggccaggga 129 <210> 8868 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8868 Asp Asn Val Asn Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Pro 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Met Val Tyr Thr Ser 20 25 30 Gly Gly Gly Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 8869 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8869 Cys Thr Val Val Ile Pro Ser Thr Pro Phe Glu Tyr Trp 1 5 10 <210> 8870 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8870 actatgacca cagacacatc cacgaacaca gcctacatgg agctgagggg tctgagatct 60 gacgacacgg ccgtgtatcg ctgtacggta gtgattcctt ctacgccctt tgaatattgg 120 ggccaggga 129 <210> 8871 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8871 Thr Met Thr Thr Asp Thr Ser Thr Asn Thr Ala Tyr Met Glu Leu Arg 1 5 10 15 Gly Leu Arg Ser Asp Asp Thr Ala Val Tyr Arg Cys Thr Val Val Ile 20 25 30 Pro Ser Thr Pro Phe Glu Tyr Trp Gly Gln Gly 35 40 <210> 8872 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8872 aatatgacca cagacacatc cacgaacaca gcctacatgg agctgagggg tctgagatct 60 gacgacacgg ccgtgtatcg ctgtacggta gtgattcctt ctacgccctt tgaatattgg 120 ggccaggga 129 <210> 8873 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8873 Asn Met Thr Thr Asp Thr Ser Thr Asn Thr Ala Tyr Met Glu Leu Arg 1 5 10 15 Gly Leu Arg Ser Asp Asp Thr Ala Val Tyr Arg Cys Thr Val Val Ile 20 25 30 Pro Ser Thr Pro Phe Glu Tyr Trp Gly Gln Gly 35 40 <210> 8874 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8874 Cys Ala Arg Val Arg Cys Ser Gly Gly Ser Cys Tyr Ser Val Gly Asp 1 5 10 15 Tyr Trp <210> 8875 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8875 acgtccacga gcacagtcta catggaggtg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgcgagtgcg ctgtagtggt ggtagttgct actccgtcgg ggactactgg 120 ggccaggga 129 <210> 8876 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8876 Thr Ser Thr Ser Thr Val Tyr Met Glu Val Ser Ser Leu Arg Ser Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Val Arg Cys Ser Gly Gly Ser 20 25 30 Cys Tyr Ser Val Gly Asp Tyr Trp Gly Gln Gly 35 40 <210> 8877 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8877 acgtccacga gcacagtcta catggaggtg agcagcctga gatctgagga cacggccgtg 60 tattactgtg cgcgagtgcg ctgtagtggt ggtagctgct actccgtcgg ggactactgg 120 ggccaggga 129 <210> 8878 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8878 Cys Ala Lys Gly Val Asp Ser Ser Gly Trp Arg Glu Gly Ala Phe Asp 1 5 10 15 Ile Trp <210> 8879 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8879 aattccaaga acacgctgta tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgaaaggagt ggatagcagt ggctggcgag aaggagcttt tgatatctgg 120 ggccaaggg 129 <210> 8880 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8880 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Val Asp Ser Ser Gly Trp 20 25 30 Arg Glu Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8881 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8881 aattccaaga acacgatgta tctgcaaatg aacagcctga gagccgagga cacggccgta 60 tattactgtg cgaaaggagt ggatagcagt ggctggcgag aaggagcttt tgatatctgg 120 ggccaaggg 129 <210> 8882 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8882 Asn Ser Lys Asn Thr Met Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gly Val Asp Ser Ser Gly Trp 20 25 30 Arg Glu Gly Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8883 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8883 Cys Ala Lys Glu Arg Gly Gly Tyr Tyr Asp Ser Ser Gly Tyr Ser Ala 1 5 10 15 Asp Ala Phe Asp Ile Trp 20 <210> 8884 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8884 acgctgtgtc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagagaggg ggggttacta tgatagtagt ggttattcgg cggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8885 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8885 Thr Leu Cys Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Glu Arg Gly Gly Tyr Tyr Asp Ser Ser Gly Tyr 20 25 30 Ser Ala Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8886 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8886 acgctgtatc tgcaaatgaa cagcctgaga gccgaggaca cggccgtata ttactgtgcg 60 aaagagaggg ggggttacta tgatagtagt ggttattcgg cggatgcttt tgatatctgg 120 ggccaaggg 129 <210> 8887 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8887 Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Lys Glu Arg Gly Gly Tyr Tyr Asp Ser Ser Gly Tyr 20 25 30 Ser Ala Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8888 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8888 Cys Ala Thr Asp Tyr Cys Ser Ile Thr Gly Cys Asn Gly Gly Tyr Tyr 1 5 10 15 Tyr Gly Met Val Val Trp 20 <210> 8889 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8889 acagtataca tggaactgag tagcctgaca tctgaggaca cggccgtgta ttattgtgcg 60 acagattatt gcagcattac cggctgtaat ggaggctact actatggtat ggtcgtctgg 120 ggccaaggg 129 <210> 8890 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8890 Thr Val Tyr Met Glu Leu Ser Ser Leu Thr Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Thr Asp Tyr Cys Ser Ile Thr Gly Cys Asn Gly Gly 20 25 30 Tyr Tyr Tyr Gly Met Val Val Trp Gly Gln Gly 35 40 <210> 8891 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8891 aaagtataca tggaactgag tagcctgaca tctgaggaca cggccgtgta ttattgtgcg 60 acagattatt gcagcattac cggctgtaat ggaggctact actatggtat ggtcgtctgg 120 ggccaaggg 129 <210> 8892 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8892 Lys Val Tyr Met Glu Leu Ser Ser Leu Thr Ser Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Thr Asp Tyr Cys Ser Ile Thr Gly Cys Asn Gly Gly 20 25 30 Tyr Tyr Tyr Gly Met Val Val Trp Gly Gln Gly 35 40 <210> 8893 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8893 Cys Ala Arg Gly Gly Tyr Cys Ser Gly Gly Ser Cys Tyr Ser Asn Tyr 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 8894 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8894 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gaggggggga 60 tattgtagtg gtggtagctg ctactccaat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8895 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8895 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Gly Tyr Cys Ser Gly Gly Ser Cys Tyr Ser Asn Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8896 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8896 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gaggggggga 60 tattgtagtg gtggtagctg ctactccaat tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8897 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8897 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Gly Tyr Cys Ser Gly Gly Ser Cys Tyr Ser Asn Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8898 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8898 Cys Ala Lys Asp Asn Gly Gly Trp Leu Ala Tyr Tyr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 8899 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8899 tacaacacgc tgtatctgca aatgaacagc ctgagagccg aggacacggc cgtatattac 60 tgtgcgaaag ataatggggg gtggctagca tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8900 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8900 Tyr Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Asp Asn Gly Gly Trp Leu Ala Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8901 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8901 aagaacacgc tgtatctgca aatgaacagc ctgagagccg aggacacggc cgtatattac 60 tgtgcgaaag ataatggggg gtggctagca tactactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8902 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8902 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Lys Asp Asn Gly Gly Trp Leu Ala Tyr Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8903 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8903 Cys Ala Arg Ser Gly His Ser Tyr Asp Phe Trp Ser Glu Val Tyr Trp 1 5 10 15 Phe Asp Pro Trp 20 <210> 8904 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8904 caagaaccag ttctcctgaa gctgagctct gtgaccgccg cggacacggc cgtgtattac 60 tgtgcgagat cgggccactc ctacgatttt tggagtgagg tttactggtt cgacccctgg 120 ggccaggga 129 <210> 8905 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8905 Gln Glu Pro Val Leu Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Ser Gly His Ser Tyr Asp Phe Trp Ser 20 25 30 Glu Val Tyr Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8906 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8906 aagaaccagt tctccctgaa gctgagctct gtgaccgccg cggacacggc cgtgtattac 60 tgtgcgagat cgggccactc ctacgatttt tggagtgagg tttactggtt cgacccctgg 120 ggccaggga 129 <210> 8907 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8907 Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Ser Gly His Ser Tyr Asp Phe Trp Ser 20 25 30 Glu Val Tyr Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8908 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8908 Cys Ala Lys Asp Ile Arg Pro His Thr Arg Pro Tyr Gly Met Asp Val 1 5 10 15 Trp <210> 8909 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8909 agacaacgcc aagaactcct gtatctgcaa atgaacagtc tgagagctga ggacacggcc 60 ttgtattact gtgcaaaaga tataaggccg cacacccggc cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8910 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8910 Arg Gln Arg Gln Glu Leu Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Ile Arg Pro His Thr 20 25 30 Arg Pro Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8911 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8911 gacaacgcca agaactccct gtatctgcaa atgaacagtc tgagagctga ggacacggcc 60 ttgtattact gtgcaaaaga tataaggccg cacacccggc cctacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8912 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8912 Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Asp Ile Arg Pro His Thr 20 25 30 Arg Pro Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8913 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8913 Cys Ala Lys Asp Gln Asp Tyr Asp Ile Leu Thr Gly Phe Glu Lys Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 8914 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8914 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggctgt gtattactgt 60 gcgaaagatc aggattacga tattttgact ggtttcgaaa aatacggtat ggatgtctgg 120 ggccaaggg 129 <210> 8915 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8915 Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Lys Asp Gln Asp Tyr Asp Ile Leu Thr Gly Phe 20 25 30 Glu Lys Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8916 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8916 aacacgctgt atctgcaaat gaacagcctg agagccgagg acacggctgt gtattactgt 60 gcgaaagatc aagattacga tattttgact ggtttcgaaa aatacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8917 <211> 25 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8917 Cys Ala Arg Gly Glu Gly Tyr Tyr Asp Phe Trp Ser Gly Tyr Arg Arg 1 5 10 15 Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 8918 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8918 ttggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagaggagag 60 gggtattacg atttttggag tggttaccgc cgctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8919 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8919 Leu Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Glu Gly Tyr Tyr Asp Phe Trp Ser Gly Tyr Arg Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8920 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8920 atggagctga ggagcctgag atctgacgac acggccgtgt attactgtgc gagaggagag 60 gggtattacg atttttggag tggttaccgc cgctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8921 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8921 Met Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 1 5 10 15 Ala Arg Gly Glu Gly Tyr Tyr Asp Phe Trp Ser Gly Tyr Arg Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8922 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8922 Cys Ala Arg Ser Gln Ile Val Val Val Ile Ala Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 8923 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8923 tgggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag gagtcagata gtagtggtta tcgcttactt tgactactgg 120 ggccaggga 129 <210> 8924 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8924 Trp Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ser Gln Ile Val Val 20 25 30 Val Ile Ala Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8925 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8925 agggacacgt ccacgagcac agtctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag gagtcagata gtagtggtta tcgcttactt tgactactgg 120 ggccaggga 129 <210> 8926 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8926 Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ser Gln Ile Val Val 20 25 30 Val Ile Ala Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8927 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8927 Cys Ala Arg Leu Gly Pro Ile Ala Ala Ala Gly Gly Pro Phe Asp Tyr 1 5 10 15 Trp <210> 8928 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8928 gacacgtcca agaaccagtt ctccctgaag ctgacctctg tgaccgccgc agacacggct 60 gtgtattact gtgcgagact ggggcccata gcagcagctg ggggaccttt tgactactgg 120 ggccaggga 129 <210> 8929 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8929 Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Thr Ser Val Thr Ala 1 5 10 15 Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Leu Gly Pro Ile Ala Ala 20 25 30 Ala Gly Gly Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8930 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8930 gacacgtcca agaaccagtt ctccctgaag ctgacctctg tgaccgccgc agacacggct 60 gtgtactact gtgcgagact ggggcccata gcagcagctg ggggaccttt tgactactgg 120 ggccaggga 129 <210> 8931 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8931 Cys Ala Arg Asp Arg Leu Glu Tyr Ser Ser Ser Asp Asp Trp Asp Pro 1 5 10 15 Phe Asp Tyr Trp 20 <210> 8932 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8932 tcgagcacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagag atcggctcga gtatagcagc tccgacgact gggacccctt tgactactgg 120 ggccaggga 129 <210> 8933 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8933 Ser Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Asp Arg Leu Glu Tyr Ser Ser Ser Asp 20 25 30 Asp Trp Asp Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8934 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8934 acgagcacag cctacatgga gctgagcagc ctgagatctg aggacacggc cgtgtattac 60 tgtgcgagag atcggctcga gtatagcagc tccgacgact gggacccctt tgactactgg 120 ggccaggga 129 <210> 8935 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8935 Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Asp Arg Leu Glu Tyr Ser Ser Ser Asp 20 25 30 Asp Trp Asp Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8936 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8936 Cys Ala Arg Asp Leu Arg Gly Leu Val Arg Ala Phe Asp Ile Trp 1 5 10 15 <210> 8937 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8937 tcagttgact cgtccaagaa ccagttctcc ctgaagctga gctctgtgac cgccgcggac 60 acggccgtgt attactgtgc gagagatctg agggggctgg tacgtgcttt tgatatctgg 120 ggccaaggg 129 <210> 8938 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8938 Ser Val Asp Ser Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu Arg Gly 20 25 30 Leu Val Arg Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8939 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8939 tcagtagaca cgtccaagaa ccagttctcc ctgaagctga gctctgtgac cgccgcggac 60 acggccgtgt attactgtgc gagagatctg agggggctgg tacgtgcttt tgatatctgg 120 ggccaaggg 129 <210> 8940 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8940 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Leu Arg Gly 20 25 30 Leu Val Arg Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 8941 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8941 Cys Val Arg Leu Ala Ala Ala Asp Gly Phe Asp Tyr Trp 1 5 10 <210> 8942 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8942 aaccatcagc cagacacatc caagaaccag ttctccctgc agctgaaata tgtgactccc 60 gaggacacgg ctgtgtatta ctgtgtaaga ttggcagcag ctgacggctt tgactactgg 120 ggccaggga 129 <210> 8943 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8943 Asn His Gln Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Lys 1 5 10 15 Tyr Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Leu Ala 20 25 30 Ala Ala Asp Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8944 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8944 accatcagcc cagacacatc caagaaccag ttctccctgc agctgaaata tgtgactccc 60 gaggacacgg ctgtgtatta ctgtgtaaga ttggcagcag ctgacggctt tgactactgg 120 ggccaggga 129 <210> 8945 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8945 Thr Ile Ser Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Lys 1 5 10 15 Tyr Val Thr Pro Glu Asp Thr Ala Val Tyr Tyr Cys Val Arg Leu Ala 20 25 30 Ala Ala Asp Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8946 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8946 Cys Ala Ser Trp Asp Ser Glu Gly Trp Tyr Phe Asp Tyr Trp 1 5 10 <210> 8947 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8947 attaccgcgg acaaatccac gagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagttgg gatagcgagg ggtggtactt tgactactgg 120 ggccaggga 129 <210> 8948 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8948 Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Trp Asp Ser 20 25 30 Glu Gly Trp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8949 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8949 attaccgcgc acaaatccac gagcacagcc tacatggagc tgagcagcct gagatctgag 60 gacacggccg tgtattactg tgcgagttgg gatagcgagg ggtggtactt tgactactgg 120 ggccaggga 129 <210> 8950 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8950 Ile Thr Ala His Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser Ser 1 5 10 15 Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Ser Trp Asp Ser 20 25 30 Glu Gly Trp Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8951 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8951 Cys Ala His Asp Arg Lys Ile Ser Leu Tyr Gly Phe Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 8952 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8952 aaccaggtgg tcctaacaat gaccaacatg gaccctgtgg acacagccac atattactgt 60 gcacacgacc ggaaaatatc gctctacggg ttctactact actatggcat ggacgtctgg 120 ggccaaggg 129 <210> 8953 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8953 Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala 1 5 10 15 Thr Tyr Tyr Cys Ala His Asp Arg Lys Ile Ser Leu Tyr Gly Phe Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8954 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8954 aacaaggtgg tcctaacaat gaccaacatg gaccctgtgt acacagccac atattactgt 60 gcacacgacc ggaaaatatc gctctacggg ttctactact actatggcat ggacgtctgg 120 ggccaaggg 129 <210> 8955 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8955 Asn Lys Val Val Leu Thr Met Thr Asn Met Asp Pro Val Tyr Thr Ala 1 5 10 15 Thr Tyr Tyr Cys Ala His Asp Arg Lys Ile Ser Leu Tyr Gly Phe Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8956 <211> 26 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8956 Cys Ala Arg Asp Ala Pro Tyr Tyr Asp Ile Leu Thr Gly Tyr Ser Asp 1 5 10 15 Pro Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 20 25 <210> 8957 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8957 gtgctgagga gcctgagatc tgacgacacg gccgtgtatt actgtgcgag agatgcccca 60 tattacgata ttttgactgg ttattccgac ccttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8958 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8958 Val Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala 1 5 10 15 Arg Asp Ala Pro Tyr Tyr Asp Ile Leu Thr Gly Tyr Ser Asp Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8959 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8959 gagctgagga gcctgagatc tgacgacacg gccgtgtatt actgtgcgag agatgcccca 60 tattacgata ttttgactgg ttattccgac ccttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8960 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8960 Glu Leu Arg Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys Ala 1 5 10 15 Arg Asp Ala Pro Tyr Tyr Asp Ile Leu Thr Gly Tyr Ser Asp Pro Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8961 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8961 Cys Ala Arg Asp Ser Gly Lys Asn Tyr Tyr Gly Met Asp Val Trp 1 5 10 15 <210> 8962 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8962 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag aggcgaggac 60 acggccgtat attactgtgc gagagattcc ggtaaaaact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8963 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8963 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Gly Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ser Gly Lys 20 25 30 Asn Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8964 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8964 tccagagata attccaacaa cacgctgtat ctgcaaatga acagcctgag aggcgaggac 60 acggccgtat attactgtgc gagagattcc ggtaaaaact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 8965 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8965 Ser Arg Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Gly Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Asp Ser Gly Lys 20 25 30 Asn Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 8966 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8966 Cys Ala His Ser His Asp Ser Ser Arg Arg Ser Pro Phe Asp Tyr Trp 1 5 10 15 <210> 8967 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8967 caaggacacc tccaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagtcatgat agtagtcgga ggtccccctt tgactactgg 120 ggccaggga 129 <210> 8968 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8968 Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser His Asp Ser Ser 20 25 30 Arg Arg Ser Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8969 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8969 aaggacacct ccaaaaacca ggtggtcctt acaatgacca acatggaccc tgtggacaca 60 gccacatatt actgtgcaca cagtcatgat agtagtcgga ggtccccctt tgactactgg 120 ggccaggga 129 <210> 8970 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8970 Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met Asp 1 5 10 15 Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser His Asp Ser Ser 20 25 30 Arg Arg Ser Pro Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 8971 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8971 Cys Ala Lys Asp Arg Ile Ala Leu Asp Gly Leu Trp Asp Ser Asp Tyr 1 5 10 15 Trp <210> 8972 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8972 gacgactcca agaacacgat gtttctccac atgaacagac tgagagtcga cgacacggcc 60 gtatatttct gtgcgaaaga ccgcattgcc cttgatggcc tctgggactc tgactactgg 120 ggccaggga 129 <210> 8973 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8973 Asp Asp Ser Lys Asn Thr Met Phe Leu His Met Asn Arg Leu Arg Val 1 5 10 15 Asp Asp Thr Ala Val Tyr Phe Cys Ala Lys Asp Arg Ile Ala Leu Asp 20 25 30 Gly Leu Trp Asp Ser Asp Tyr Trp Gly Gln Gly 35 40 <210> 8974 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8974 Cys Ala Arg Glu Gly Gly Thr Thr Val Ala Thr Gly Arg Phe Asp Pro 1 5 10 15 Trp <210> 8975 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8975 cacacatcca cgaccacagc ctacatggag ctgaggagcc tgagatctga cgacacggcc 60 gtctactact gtgcgagaga gggtggcact acggtggcta ctggacggtt cgacccctgg 120 ggccaggga 129 <210> 8976 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8976 His Thr Ser Thr Thr Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly Gly Thr Thr Val 20 25 30 Ala Thr Gly Arg Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8977 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8977 gacacatcca cgaccacagc ctacatggag ctgaggagcc tgagatctga cgacacggcc 60 gtctactact gtgcgagaga gggtggcact acggtggcta ctggacggtt cgacccctgg 120 ggccaggga 129 <210> 8978 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8978 Asp Thr Ser Thr Thr Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser 1 5 10 15 Asp Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Gly Gly Thr Thr Val 20 25 30 Ala Thr Gly Arg Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 8979 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8979 Cys Ala Arg Glu Lys Tyr Gly Asp Glu Ile Asp Tyr Trp 1 5 10 <210> 8980 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8980 accatgacct gggacacgtc cacgagcaca gtctacttgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga gagaaatacg gtgacgagat tgactactgg 120 ggccaggga 129 <210> 8981 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8981 Thr Met Thr Trp Asp Thr Ser Thr Ser Thr Val Tyr Leu Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Lys 20 25 30 Tyr Gly Asp Glu Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 8982 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8982 accatgacca gggacacgtc cacgagcaca gtctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga gagaaatacg gtgacgagat tgactactgg 120 ggccaggga 129 <210> 8983 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8983 Thr Met Thr Arg Asp Thr Ser Thr Ser Thr Val Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Glu Lys 20 25 30 Tyr Gly Asp Glu Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 8984 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8984 Cys Ala Arg Gly Arg Asn Ser Gly Ser Tyr Tyr Pro Trp 1 5 10 <210> 8985 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8985 accatgacca ggaacacctc cataagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ggacgaaata gtgggagcta ctacccttgg 120 ggccaggga 129 <210> 8986 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8986 Thr Met Thr Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg 20 25 30 Asn Ser Gly Ser Tyr Tyr Pro Trp Gly Gln Gly 35 40 <210> 8987 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8987 accatgacca gcaacacctc cataagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ggacgaaata gtgggagcta ctacccttgg 120 ggccaggga 129 <210> 8988 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8988 Thr Met Thr Ser Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Arg 20 25 30 Asn Ser Gly Ser Tyr Tyr Pro Trp Gly Gln Gly 35 40 <210> 8989 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8989 Cys Ala His Ser Arg Asp Ser Ser Ser Trp Tyr Val Asp Tyr Trp 1 5 10 15 <210> 8990 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8990 accaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacat attactgtgc acacagtagg gatagcagca gctggtatgt tgactactgg 120 ggccaggga 129 <210> 8991 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8991 Thr Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala His Ser Arg Asp Ser 20 25 30 Ser Ser Trp Tyr Val Asp Tyr Trp Gly Gln Gly 35 40 <210> 8992 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8992 accaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacat attactgtgc acacagtagg gacagcagca gctggtatgt tgactactgg 120 ggccaggga 129 <210> 8993 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8993 Cys Ala Arg Ile Pro Asp Tyr Gly Ser Gly Ser Lys Asn Tyr Trp 1 5 10 15 <210> 8994 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8994 tccagagata attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaggataccc gactatggtt cggggagtaa gaactactgg 120 ggccaggga 129 <210> 8995 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8995 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ile Pro Asp Tyr 20 25 30 Gly Ser Gly Ser Lys Asn Tyr Trp Gly Gln Gly 35 40 <210> 8996 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8996 tacagagata attccaagaa cacgctgtat ctgaaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaggataccc gactatggtt cggggagtaa gaactactgg 120 ggccaggga 129 <210> 8997 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8997 Tyr Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Lys Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ile Pro Asp Tyr 20 25 30 Gly Ser Gly Ser Lys Asn Tyr Trp Gly Gln Gly 35 40 <210> 8998 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8998 Cys Met His Asp Phe Trp Asn Gly Met Val Gly Phe Asp Phe Trp 1 5 10 15 <210> 8999 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 8999 tccagagatg attcaaaggg tacggcgtat ctgcaaatga acagtctgaa aagcgaggac 60 acggccgtgt attattgtat gcacgatttt tggaatggta tggttggatt tgacttctgg 120 ggccaggga 129 <210> 9000 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9000 Ser Arg Asp Asp Ser Lys Gly Thr Ala Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Lys Ser Glu Asp Thr Ala Val Tyr Tyr Cys Met His Asp Phe Trp Asn 20 25 30 Gly Met Val Gly Phe Asp Phe Trp Gly Gln Gly 35 40 <210> 9001 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9001 tccagagatg attcaaaggg tacggcgtat ctgaaaatga acagtctcaa aagcgaggac 60 acggccgtgt attattgtat gcacgatttt tggaatggta tggttggatt tgacttctgg 120 ggccaggga 129 <210> 9002 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9002 Ser Arg Asp Asp Ser Lys Gly Thr Ala Tyr Leu Lys Met Asn Ser Leu 1 5 10 15 Lys Ser Glu Asp Thr Ala Val Tyr Tyr Cys Met His Asp Phe Trp Asn 20 25 30 Gly Met Val Gly Phe Asp Phe Trp Gly Gln Gly 35 40 <210> 9003 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9003 Cys Ala Arg Gly Gln Ser Val Ala Gly Gly Phe Asp Tyr Trp 1 5 10 <210> 9004 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9004 atctccatag aaaatgccaa gaactccttg tatcttcaaa tgaacagcct gagagccggt 60 gacacggctg tgtattactg tgcaagaggt caaagcgtgg ctggcggttt tgactactgg 120 ggccaggga 129 <210> 9005 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9005 Ile Ser Ile Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gln Ser 20 25 30 Val Ala Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9006 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9006 atctccagag aaaatgccaa gaactccttg tatcttcaaa tgaacagcct gagagccggg 60 gacacggctg tgtattactg tgcaagaggt caaagcgtgg ctggcggttt tgactactgg 120 ggccaggga 129 <210> 9007 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9007 Ile Ser Arg Glu Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Ala Gly Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gln Ser 20 25 30 Val Ala Gly Gly Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9008 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9008 Cys Ala Arg Glu Gly Gly Tyr Gly Ser Gly Ser Phe His Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 9009 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9009 tgcacagtct acttggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagagg gaggctatgg ttcggggagt tttcactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 9010 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9010 Cys Thr Val Tyr Leu Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Gly Gly Tyr Gly Ser Gly Ser Phe His 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9011 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9011 agcacagtct acatggagct gagcagcctg agatctgagg acacggccgt gtattactgt 60 gcgagagagg gaggctatgg ttcggggagt tttcactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 9012 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9012 Ser Thr Val Tyr Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg Glu Gly Gly Tyr Gly Ser Gly Ser Phe His 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9013 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9013 Cys Ala Lys Gly Gly Gly Tyr Asp Ile Leu Thr Gly Tyr Leu Gly Gly 1 5 10 15 Met Asp Val Trp 20 <210> 9014 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9014 aaggactccc tgtatctgca aatgaacagt ctgagagctg aggacacggc cttgtattac 60 tgtgcaaaag gagggggtta cgatattttg actggttacc ttgggggtat ggacgtctgg 120 ggccaaggg 129 <210> 9015 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9015 Lys Asp Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Leu Tyr Tyr Cys Ala Lys Gly Gly Gly Tyr Asp Ile Leu Thr Gly 20 25 30 Tyr Leu Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9016 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9016 aagaactccc tgtatctgca aatgaacagt ctgagagctg aggacacggc cttgtattac 60 tgtgcaaaag gagggggtta cgatattttg actggttacc ttgggggtat ggacgtctgg 120 ggccaaggg 129 <210> 9017 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9017 Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Leu Tyr Tyr Cys Ala Lys Gly Gly Gly Tyr Asp Ile Leu Thr Gly 20 25 30 Tyr Leu Gly Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9018 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9018 Cys Thr Arg Gly Tyr Ser Ser Gly Trp Ser Pro Arg Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 9019 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9019 aacacggcgt atctgcaaat gaacagcctg aaaaccgagg acacggccgt gtattactgt 60 actagggggt atagcagtgg ctggtcacca cgttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 9020 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9020 Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Thr Arg Gly Tyr Ser Ser Gly Trp Ser Pro Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9021 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9021 tacacggcgt atctgcaaat gaacagcctg aaaaccgagg acacggccgt gtattactgt 60 actagggggt atagcagtgg ctggtcacca cgttactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 9022 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9022 Tyr Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Thr Arg Gly Tyr Ser Ser Gly Trp Ser Pro Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9023 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9023 Cys Ala Arg His Ser Asp Pro Ala Val Ala Gly Arg Tyr Tyr Tyr Tyr 1 5 10 15 Gly Met Asp Val Trp 20 <210> 9024 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9024 aaccagttct ccctgaagct gggctctgtg accgccgcag acacggctgt gtattactgt 60 gcgagacatt cggacccagc agtggctggt cgctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 9025 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9025 Asn Gln Phe Ser Leu Lys Leu Gly Ser Val Thr Ala Ala Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg His Ser Asp Pro Ala Val Ala Gly Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9026 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9026 aaccagttct ccctgaagct gagctctgtg accgccgcag acacggctgt gtattactgt 60 gcgagacatt cggacccagc agtggctggt cgctactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 9027 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9027 Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala 1 5 10 15 Val Tyr Tyr Cys Ala Arg His Ser Asp Pro Ala Val Ala Gly Arg Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9028 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9028 Cys Ala Arg Gly Pro Val Gly Ala Thr Thr Ala Ala Arg Asp Tyr Trp 1 5 10 15 <210> 9029 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9029 tgcaacacct ccataagcac agcctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag aggtccagtg ggagctacta cagccgcgcg ggactactgg 120 ggccaggga 129 <210> 9030 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9030 Cys Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Pro Val Gly Ala 20 25 30 Thr Thr Ala Ala Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 9031 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9031 aggaacacct ccataagcac agcctacatg gagctgagca gcctgagatc tgaggacacg 60 gccgtgtatt actgtgcgag aggtccagtg ggagctacta cagccgcgcg ggactactgg 120 ggccaggga 129 <210> 9032 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9032 Arg Asn Thr Ser Ile Ser Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Pro Val Gly Ala 20 25 30 Thr Thr Ala Ala Arg Asp Tyr Trp Gly Gln Gly 35 40 <210> 9033 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9033 Cys Gly Arg Glu Gly Gln Glu Asp Gly Asp Tyr Gly Thr His Ile Asp 1 5 10 15 Ser Trp <210> 9034 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9034 acgtccaata atcaattctc ccttaaactg ggctctgtga ccgaggcgga cacggccgtc 60 tactattgtg ggagagaagg gcaggaagac ggtgactacg ggacacacat tgactcctgg 120 ggccaggga 129 <210> 9035 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9035 Thr Ser Asn Asn Gln Phe Ser Leu Lys Leu Gly Ser Val Thr Glu Ala 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Gly Arg Glu Gly Gln Glu Asp Gly Asp 20 25 30 Tyr Gly Thr His Ile Asp Ser Trp Gly Gln Gly 35 40 <210> 9036 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9036 acgtccaata atcaattctc ccttaaactg ggctctgtga ccgaagcgga cacggccgtc 60 tactattgtg ggagagaagg gcaggaagac ggtgactacg ggacacacat tgactcctgg 120 ggccaggga 129 <210> 9037 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9037 Cys Ala Arg Asp Gln Thr Val Val Thr Gly Asp Tyr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val Trp 20 <210> 9038 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9038 aagaacacgc tgtatctgca aatgaacagt ctgagagccg aggacacggc tgtgtattac 60 tgtgcaagag atcaaacggt ggtaaccggg gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 9039 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9039 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Asp Gln Thr Val Val Thr Gly Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9040 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9040 aagaacacgc tgtatctgca aatgaacagt ctgagagccg aggacacggc tgtgcattac 60 tgtgcaagag atcaaacggt ggtaaccggg gattactact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 9041 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9041 Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val His Tyr Cys Ala Arg Asp Gln Thr Val Val Thr Gly Asp Tyr 20 25 30 Tyr Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9042 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9042 Cys Ala Arg Asp Arg Pro Asn Cys Leu Ser Cys Leu Asp Tyr Trp 1 5 10 15 <210> 9043 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9043 tacccagaca catccaagaa ccagttctcc ctgcagctga actctgtgac tcccgaggac 60 tctgctgtgt attactgtgc aagagaccgt cctaactgcc taagttgttt agactactgg 120 ggccaggga 129 <210> 9044 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9044 Tyr Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser Val 1 5 10 15 Thr Pro Glu Asp Ser Ala Val Tyr Tyr Cys Ala Arg Asp Arg Pro Asn 20 25 30 Cys Leu Ser Cys Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 9045 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9045 aacccagaca catccaagaa ccagttctcc ctgcagctga actctgtgac tcccgaggac 60 tcggctgtgt attactgtgc aagagaccgt cctaactgcc taagttgttt agactactgg 120 ggccaggga 129 <210> 9046 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9046 Asn Pro Asp Thr Ser Lys Asn Gln Phe Ser Leu Gln Leu Asn Ser Val 1 5 10 15 Thr Pro Glu Asp Ser Ala Val Tyr Tyr Cys Ala Arg Asp Arg Pro Asn 20 25 30 Cys Leu Ser Cys Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 9047 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9047 Cys Ala Arg Ala Glu Gln Trp Leu Val Leu Gly Ile Leu Asp Phe Asp 1 5 10 15 Tyr Trp <210> 9048 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9048 tcatccacga gcacagccta catggagctg aggagcctga gatctgacga cacggccgtg 60 tattactgtg cgagagccga gcagtggctg gtactcggga tcctggactt tgactactgg 120 ggccaggga 129 <210> 9049 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9049 Ser Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Glu Gln Trp Leu Val Leu 20 25 30 Gly Ile Leu Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9050 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9050 acatccacga gcacagccta catggagctg aggagcctga gatctgacga cacggccgtg 60 tattactgtg cgagagccga gcagtggctg gtactcggga tcctggactt tgactactgg 120 ggccaggga 129 <210> 9051 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9051 Thr Ser Thr Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Arg Ser Asp 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Ala Glu Gln Trp Leu Val Leu 20 25 30 Gly Ile Leu Asp Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9052 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9052 Cys Thr Arg His Leu Trp Asp Ser Ser Gly Tyr Tyr Tyr Tyr Tyr Phe 1 5 10 15 Asp Tyr Trp <210> 9053 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9053 tcaaagaaca cggcgtatct gcaaatgaac agcctgaaaa ccgaggacac ggccgtgtat 60 tactgtacta gacatctctg ggatagtagt ggttattact actactactt tgactactgg 120 ggccaggga 129 <210> 9054 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9054 Ser Lys Asn Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Arg His Leu Trp Asp Ser Ser Gly Tyr 20 25 30 Tyr Tyr Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9055 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9055 caaagaacca cggcgtatct gcaaatgaac agcctgaaaa ccgaggacac ggccgtgtat 60 tactgtacta gacatctctg ggatagtagt ggttattact actactactt tgactactgg 120 ggccaggga 129 <210> 9056 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9056 Gln Arg Thr Thr Ala Tyr Leu Gln Met Asn Ser Leu Lys Thr Glu Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Thr Arg His Leu Trp Asp Ser Ser Gly Tyr 20 25 30 Tyr Tyr Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9057 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9057 Cys Ala Arg Thr Gly Ser Gly Arg Ser Asp Trp Phe Asp Pro Trp 1 5 10 15 <210> 9058 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9058 ctccaaggac acctccaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acggacaggt tcggggaggt cagactggtt cgacccctgg 120 ggccaggga 129 <210> 9059 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9059 Leu Gln Gly His Leu Gln Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Thr Gly Ser Gly 20 25 30 Arg Ser Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 9060 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9060 tccaaggaca cctccaaaaa ccaggtggtc cttacaatga ccaacatgga ccctgtggac 60 acagccacgt attactgtgc acggacaggt tcggggaggt cagactggtt cgacccctgg 120 ggccaggga 129 <210> 9061 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9061 Ser Lys Asp Thr Ser Lys Asn Gln Val Val Leu Thr Met Thr Asn Met 1 5 10 15 Asp Pro Val Asp Thr Ala Thr Tyr Tyr Cys Ala Arg Thr Gly Ser Gly 20 25 30 Arg Ser Asp Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 9062 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9062 Cys Ala Lys Asp Ser Gly Asp Asp Tyr Ser Asn Tyr Trp 1 5 10 <210> 9063 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9063 accatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gattccgggg atgactacag taactactgg 120 ggccaggga 129 <210> 9064 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9064 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Ser 20 25 30 Gly Asp Asp Tyr Ser Asn Tyr Trp Gly Gln Gly 35 40 <210> 9065 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9065 accatctcca gagacaattc caagaacacg ctgtatctgc aaatgaacag cctgagagcc 60 gaggacacgg ccgtatatta ctgtgcgaaa gattccgggg atgactacag taactactgg 120 agccaggga 129 <210> 9066 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9066 Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Ser 20 25 30 Gly Asp Asp Tyr Ser Asn Tyr Trp Ser Gln Gly 35 40 <210> 9067 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9067 Cys Ala Lys Gly Gly Val Glu Ser Gly Asp Phe Trp 1 5 10 <210> 9068 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9068 ttcaccatct ccagatataa ttccaagaat atggtgtttc tgcaagtgaa cagcctgaga 60 gtcgaggaca cggccatata ttactgtgcg aaaggggggg tcgagagcgg agacttctgg 120 ggccaggga 129 <210> 9069 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9069 Phe Thr Ile Ser Arg Tyr Asn Ser Lys Asn Met Val Phe Leu Gln Val 1 5 10 15 Asn Ser Leu Arg Val Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Lys Gly 20 25 30 Gly Val Glu Ser Gly Asp Phe Trp Gly Gln Gly 35 40 <210> 9070 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9070 ttcaccatct ccagagataa ttccaagaat atggtgtttc tgcaagtgaa cagcctgaga 60 gtcgaggaca cggccatata ttactgtgcg aaaggggggg tcgagagcgg agacttctgg 120 ggccaggga 129 <210> 9071 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9071 Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Met Val Phe Leu Gln Val 1 5 10 15 Asn Ser Leu Arg Val Glu Asp Thr Ala Ile Tyr Tyr Cys Ala Lys Gly 20 25 30 Gly Val Glu Ser Gly Asp Phe Trp Gly Gln Gly 35 40 <210> 9072 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9072 Cys Ala Lys Gln Tyr Ser Ser Gly Ser Thr Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 9073 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9073 agagagaaat ccaagaccac gctgtatctg caaatgaaca gcctgagggt cgacgacacg 60 gccgtatatt actgtgcgaa gcagtatagc agcggctcca catattactt tgactactgg 120 ggccaggga 129 <210> 9074 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9074 Arg Glu Lys Ser Lys Thr Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Val Asp Asp Thr Ala Val Tyr Tyr Cys Ala Lys Gln Tyr Ser Ser Gly 20 25 30 Ser Thr Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9075 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9075 agagagaaat ccaagaccac gctgtatctg caaatgaaca gcctgagagt cgacgacacg 60 gccgtatatt actgtgcgaa gcagtatagc agcggctcca catattactt tgactactgg 120 ggccaggga 129 <210> 9076 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9076 Cys Ala Arg Met Leu Pro Pro Met Ser Leu Gly Tyr Tyr Gly Met Asp 1 5 10 15 Val Trp <210> 9077 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9077 aattccaaga acacgctgta tctgcaaatg aacagtctga gagccgagga cacggctgtg 60 tattactgtg caaggatgct acccccaatg agtctgggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 9078 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9078 Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Met Leu Pro Pro Met Ser Leu 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9079 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9079 aacgccaaga acacgctgta tctgcaaatg aacagtctga gagccgagga cacggctgtg 60 tattactgtg caaggatgct acccccaatg agtctgggct actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 9080 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9080 Asn Ala Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu 1 5 10 15 Asp Thr Ala Val Tyr Tyr Cys Ala Arg Met Leu Pro Pro Met Ser Leu 20 25 30 Gly Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9081 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9081 Cys Ala Lys Pro Tyr Asp Ser Asn Leu Gly Tyr Phe Gln His Trp 1 5 10 15 <210> 9082 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9082 tccagagaca attccaagaa cacgctgtat ctgcaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaccgtat gacagtaact tagggtactt ccagcactgg 120 ggccagggc 129 <210> 9083 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9083 Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu 1 5 10 15 Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Pro Tyr Asp Ser 20 25 30 Asn Leu Gly Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 9084 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9084 tccagagaca attccaagaa cacgctgtat ctacaaatga acagcctgag agccgaggac 60 acggccgtat attactgtgc gaaaccgtat gacagtaact tagggtactt ccagcactgg 120 ggccagggc 129 <210> 9085 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9085 Cys Ala Arg Asp Leu Ala Leu Tyr Asp Ile Leu Thr Ala Arg Gly Ala 1 5 10 15 Glu Tyr Phe Gln His Trp 20 <210> 9086 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9086 tcactgtatc tgcaaatgaa cagcctgaga gacgaggaca cggctgtgta ttactgtgcg 60 agagatctcg ccctatacga tattttgacg gccagggggg ctgaatactt ccagcactgg 120 ggccagggc 129 <210> 9087 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9087 Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Leu Ala Leu Tyr Asp Ile Leu Thr Ala Arg 20 25 30 Gly Ala Glu Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 9088 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9088 tcaatgtatc tgcaaatgaa cagcctgaga gacgaggaca cggctgtgta ttactgtgcg 60 agagatctcg ccctatacga tattttgacg gccagggggg ctgaatactt ccagcactgg 120 ggccagggc 129 <210> 9089 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9089 Ser Met Tyr Leu Gln Met Asn Ser Leu Arg Asp Glu Asp Thr Ala Val 1 5 10 15 Tyr Tyr Cys Ala Arg Asp Leu Ala Leu Tyr Asp Ile Leu Thr Ala Arg 20 25 30 Gly Ala Glu Tyr Phe Gln His Trp Gly Gln Gly 35 40 <210> 9090 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9090 Cys Ala His Ser Leu Val Asp Ile Val Ala Thr Thr Pro Ser Tyr Trp 1 5 10 15 Tyr Phe Asp Leu Trp 20 <210> 9091 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9091 ttccaggtgg tccttacaat gaccaacatg gaccctgtgg acacagccac atattactgt 60 gctcactccc tcgtggatat agtggctacg acaccaagct actggtactt cgatctctgg 120 ggccgtggc 129 <210> 9092 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9092 Phe Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala 1 5 10 15 Thr Tyr Tyr Cys Ala His Ser Leu Val Asp Ile Val Ala Thr Thr Pro 20 25 30 Ser Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 9093 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9093 aaccaggtgg tccttacaat gaccaacatg gaccctgtgg acacagccac atattactgt 60 gctcactccc tcgtggatat agtggctacg acaccaagct actggtactt cgatctctgg 120 ggccgtggc 129 <210> 9094 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9094 Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala 1 5 10 15 Thr Tyr Tyr Cys Ala His Ser Leu Val Asp Ile Val Ala Thr Thr Pro 20 25 30 Ser Tyr Trp Tyr Phe Asp Leu Trp Gly Arg Gly 35 40 <210> 9095 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9095 Cys Ala Lys Asp Trp Ser Tyr Cys Ser Ser Thr Ser Cys Tyr Phe Tyr 1 5 10 15 Ser Val Gly Trp Phe Asp Pro Trp 20 <210> 9096 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9096 tttctgaaaa tgaacagcct gagagccgag gacacggccg tatattactg tgcgaaagat 60 tggtcgtatt gtagtagtac cagctgctat ttttactcgg ttggctggtt cgacccctgg 120 ggccaggga 129 <210> 9097 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9097 Phe Leu Lys Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Trp Ser Tyr Cys Ser Ser Thr Ser Cys Tyr Phe Tyr 20 25 30 Ser Val Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 9098 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9098 tatctgcaaa tgaacagcct gagagccgag gacacggccg tatattactg tgcgaaagat 60 tggtcgtatt gtagtagtac cagctgctat ttttactcgg ttggctggtt cgacccctgg 120 ggccaggga 129 <210> 9099 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9099 Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr 1 5 10 15 Cys Ala Lys Asp Trp Ser Tyr Cys Ser Ser Thr Ser Cys Tyr Phe Tyr 20 25 30 Ser Val Gly Trp Phe Asp Pro Trp Gly Gln Gly 35 40 <210> 9100 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9100 Cys Ala Arg Gly His Gly Ser Gly Leu Leu Gly Tyr Tyr Tyr Tyr Gly 1 5 10 15 Leu Asp Val Trp 20 <210> 9101 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9101 aataacacgc tttatctaca aatgagcagt ctgagagctg aggacacggc tgtatattac 60 tgtgcccgag gccatggttc gggattattg ggctactact actacggtct ggacgtctgg 120 ggccagggg 129 <210> 9102 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9102 Asn Asn Thr Leu Tyr Leu Gln Met Ser Ser Leu Arg Ala Glu Asp Thr 1 5 10 15 Ala Val Tyr Tyr Cys Ala Arg Gly His Gly Ser Gly Leu Leu Gly Tyr 20 25 30 Tyr Tyr Tyr Gly Leu Asp Val Trp Gly Gln Gly 35 40 <210> 9103 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9103 aataacacgc tgtatctaca aatgagcagt ctgagagctg aggacacggc tgtatattac 60 tgtgcccgag gccatggttc gggattattg ggctactact actacggtct ggacgtctgg 120 ggccagggg 129 <210> 9104 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9104 Cys Ala Arg Pro Asp Asp Tyr Tyr Gly Met Asp Val Trp 1 5 10 <210> 9105 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9105 acgattaccg cggacaaatc cacgagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ccagacgact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 9106 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9106 Thr Ile Thr Ala Asp Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Pro Asp 20 25 30 Asp Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9107 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9107 acgattaccg cgcacaaatc cacgagcaca gcctacatgg agctgagcag cctgagatct 60 gaggacacgg ccgtgtatta ctgtgcgaga ccagacgact actacggtat ggacgtctgg 120 ggccaaggg 129 <210> 9108 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9108 Thr Ile Thr Ala His Lys Ser Thr Ser Thr Ala Tyr Met Glu Leu Ser 1 5 10 15 Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys Ala Arg Pro Asp 20 25 30 Asp Tyr Tyr Gly Met Asp Val Trp Gly Gln Gly 35 40 <210> 9109 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9109 Cys Ala Arg His Glu Gly Thr Asp Ile Val Val Val Pro Ala Ala Leu 1 5 10 15 Asp Tyr Trp <210> 9110 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9110 tccaggaacc agttctccct gaagctgagc tctgtgaccg ccgcagacac ggctgtgtat 60 tactgtgcga gacatgaggg gaccgatatt gtagtagtac cagctgccct tgactactgg 120 ggccaggga 129 <210> 9111 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9111 Ser Arg Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg His Glu Gly Thr Asp Ile Val Val 20 25 30 Val Pro Ala Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 9112 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9112 tccaagaacc agttctccct gaagctgagc tctgtgaccg ccgcagacac ggctgtgtat 60 tactgtgcga gacatgaggg gaccgatatt gtagtagtac cagctgccct tgactactgg 120 ggccaggga 129 <210> 9113 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9113 Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val Thr Ala Ala Asp 1 5 10 15 Thr Ala Val Tyr Tyr Cys Ala Arg His Glu Gly Thr Asp Ile Val Val 20 25 30 Val Pro Ala Ala Leu Asp Tyr Trp Gly Gln Gly 35 40 <210> 9114 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9114 Cys Ala Arg Ser Leu Asn Ser Tyr Ser Phe Glu Gln Phe Asp His Trp 1 5 10 15 <210> 9115 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9115 tgggacacat ccgcgagcac agcctacatg gaattgagaa gcctcggatc tgaagacacg 60 gctgtgtatt tctgtgctcg atctctgaat agttatagtt ttgaacagtt cgaccactgg 120 ggccaggga 129 <210> 9116 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9116 Trp Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Gly 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Ser Leu Asn Ser Tyr 20 25 30 Ser Phe Glu Gln Phe Asp His Trp Gly Gln Gly 35 40 <210> 9117 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9117 agggacacat ccgcgagcac agcctacatg gaattgagaa gcctcggatc tgaagacacg 60 gctgtgtatt tctgtgctcg atctctgaat agttatagtt ttgaacagtt cgaccactgg 120 ggccaggga 129 <210> 9118 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9118 Arg Asp Thr Ser Ala Ser Thr Ala Tyr Met Glu Leu Arg Ser Leu Gly 1 5 10 15 Ser Glu Asp Thr Ala Val Tyr Phe Cys Ala Arg Ser Leu Asn Ser Tyr 20 25 30 Ser Phe Glu Gln Phe Asp His Trp Gly Gln Gly 35 40 <210> 9119 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9119 Cys Ala Lys Asp Arg Gly Gly Gly Ser Tyr Tyr Gly Thr Phe Asp Tyr 1 5 10 15 Trp <210> 9120 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9120 gataattcca agaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga tcgcgggggt gggagctact acgggacctt tgactactgg 120 ggccaggga 129 <210> 9121 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9121 Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Gly Gly Gly Ser 20 25 30 Tyr Tyr Gly Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9122 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9122 gataattcca acaacacgct gtatctgcaa atgaacagcc tgagagccga ggacacggcc 60 gtatattact gtgcgaaaga tcgcgggggt gggagctact acgggacctt tgactactgg 120 ggccaggga 129 <210> 9123 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9123 Asp Asn Ser Asn Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala 1 5 10 15 Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Asp Arg Gly Gly Gly Ser 20 25 30 Tyr Tyr Gly Thr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9124 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9124 Cys Ala Arg Gly Asn Trp Gly Phe Gly Gly Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 9125 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9125 tcagtagaca cgtctaagaa ccagttctcc ctgaagctga gctctgtgac tgccgcggac 60 acggccgtgt attactgtgc gagaggaaac tggggattcg gggggtactt tgactactgg 120 ggccaggga 129 <210> 9126 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9126 Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asn Trp Gly 20 25 30 Phe Gly Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9127 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9127 tcagtagaca cgtcaaacaa ccagttctcc ctgaagctga gctctgtgac tgccgcggac 60 acggccgtgt attactgtgc gagaggaaac tggggattcg gggggtactt tgactactgg 120 ggccaggga 129 <210> 9128 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9128 Ser Val Asp Thr Ser Asn Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Asn Trp Gly 20 25 30 Phe Gly Gly Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9129 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9129 Cys Ala Lys Val Asp Ser Ser Gly Tyr Tyr Tyr Tyr Phe Asp Tyr Trp 1 5 10 15 <210> 9130 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9130 ttagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agtggatagt agtggttatt actactactt tgactactgg 120 ggccaggga 129 <210> 9131 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9131 Leu Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Asp Ser Ser Gly 20 25 30 Tyr Tyr Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9132 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9132 agagataatt ccaagaacac gctgtatctg caaatgaaca gcctgagagc cgaggacacg 60 gccgtatatt actgtgcgaa agtggatagt agtggttatt actactactt tgactactgg 120 ggccaggga 129 <210> 9133 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9133 Arg Asp Asn Ser Lys Asn Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg 1 5 10 15 Ala Glu Asp Thr Ala Val Tyr Tyr Cys Ala Lys Val Asp Ser Ser Gly 20 25 30 Tyr Tyr Tyr Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9134 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9134 Cys Ala Arg Gly Gly Asn Pro Glu His Asp Ala Phe Asp Ile Trp 1 5 10 15 <210> 9135 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9135 tccgttgaca ggtccaagaa ccagttctcc ctgaagctga gctctgtgac cgccgcggac 60 acggccgtgt attactgtgc cagagggggg aaccccgagc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 9136 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9136 Ser Val Asp Arg Ser Lys Asn Gln Phe Ser Leu Lys Leu Ser Ser Val 1 5 10 15 Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg Gly Gly Asn Pro 20 25 30 Glu His Asp Ala Phe Asp Ile Trp Gly Gln Gly 35 40 <210> 9137 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9137 tcagtagaca ggtccaagaa ccagttctcc ctgaagctga gctctgtgac cgccgcggac 60 acggccgtgt attactgtgc cagagggggg aaccccgagc atgatgcttt tgatatctgg 120 ggccaaggg 129 <210> 9138 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9138 Cys Val Lys Glu Lys Thr Gly Thr Ala Tyr Phe Asp Tyr Trp 1 5 10 <210> 9139 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9139 atctccagag acaacgccaa gaactccctg tatctgcaaa tgaacagtct gagagtggag 60 gacacggcct tgtattactg tgtaaaagaa aagactggga ccgcctattt tgactactgg 120 ggccaggga 129 <210> 9140 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9140 Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Val Glu Asp Thr Ala Leu Tyr Tyr Cys Val Lys Glu Lys Thr 20 25 30 Gly Thr Ala Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9141 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9141 atctccagag acaacgccaa gaaccccctg tatctacaaa tgaacagtct gagagtggag 60 gacacggcct tgtattactg tgtaaaagaa aagactggga ccgcctattt tgactactgg 120 ggccaggga 129 <210> 9142 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9142 Ile Ser Arg Asp Asn Ala Lys Asn Pro Leu Tyr Leu Gln Met Asn Ser 1 5 10 15 Leu Arg Val Glu Asp Thr Ala Leu Tyr Tyr Cys Val Lys Glu Lys Thr 20 25 30 Gly Thr Ala Tyr Phe Asp Tyr Trp Gly Gln Gly 35 40 <210> 9143 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9143 Cys Ala Lys Ser Pro Asp Thr Ala Met Ile Asp Tyr Trp 1 5 10 <210> 9144 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9144 caccatctcc agagacaaca gcaaaactcc ctgtatctgc aaatgaacag tctgagagct 60 gaggacaccg ccttgtatta ctgtgcaaaa tccccggata cagctatgat tgactactgg 120 ggccaggga 129 <210> 9145 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9145 His His Leu Gln Arg Gln Gln Gln Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Ser Pro 20 25 30 Asp Thr Ala Met Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 9146 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9146 accatctcca gagacaacag caaaaactcc ctgtatctgc aaatgaacag tctgagagct 60 gaggacaccg ccttgtatta ctgtgcaaaa tccccggata cagctatgat tgactactgg 120 ggccaggga 129 <210> 9147 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9147 Thr Ile Ser Arg Asp Asn Ser Lys Asn Ser Leu Tyr Leu Gln Met Asn 1 5 10 15 Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys Ala Lys Ser Pro 20 25 30 Asp Thr Ala Met Ile Asp Tyr Trp Gly Gln Gly 35 40 <210> 9148 <211> 12 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9148 Cys Ala Arg His Pro Trp Gln Gln Leu Ser Tyr Trp 1 5 10 <210> 9149 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9149 gtcaccatat ccgtagacac gtccaagaat cagttctccc tgaagctgag ctctgtgacc 60 gccgcagaca cggctgtgta ttactgtgcg agacatccct ggcagcagct gtcctactgg 120 ggccaggga 129 <210> 9150 <211> 43 <212> PRT <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9150 Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Phe Ser Leu Lys Leu 1 5 10 15 Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala Arg His 20 25 30 Pro Trp Gln Gln Leu Ser Tyr Trp Gly Gln Gly 35 40 <210> 9151 <211> 129 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: Synthetic antibody <400> 9151 gtcaccatat ccgtagacac gtccaagaat cagttctccc tgaagctgag ctctgtgacc 60 gccgcagaca cggctgtgta ttactgcgcg agacatccct ggcagcagct gtcctactgg 120 ggccaggga 129 <210> 9152 <211> 354 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9152 caggtgcagc tggtgcaatc tgggtctgag ttgcagaagc ctggggcctc agtgaaggtt 60 tcctgtaagg cttctggaaa caccttccct acttatgata tgaattgggt gcgacaggcc 120 cctggacaag ggcttgagtg gatgggatgg atcaacacca acactgggag cccaacgtat 180 gcccagggct taccaggacg gtttgtcttc tccttggaca catctgtcag cacggcatat 240 ctggagatca gcagcctaaa ggctgaggac actgccgtgt attactgtgc gagagagggg 300 tatcactacg gtatggacgt ctggggccaa gggaccacgg tcaccgtctc ctca 354 <210> 9153 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9153 gacatccaga tgacccagtc tccatcctca ctgtctgcct ctgtaggaga cagagtcacc 60 atcacttgtc gggcgagtca ggacattaac aattatttag cctggtttca gcagaaacca 120 ggtaaagccc ctaagtccct gatctattct gcgtccagtt tgcaaagtgg ggtcccatcg 180 aggttcagcg gcagtggatc tgggacagat ttcactctca ccatcagcag cctgcagcct 240 gaagattttg caacttatta ttgccaacag tatcgtagtt accctcggac ttttggccag 300 gggaccaagc tggagatcaa ac 322 <210> 9154 <211> 358 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9154 caggcacacc tggtgcagtc tggggctgag gtgaagaagc ctgggtcctc ggtgaaggtc 60 tcctgcaagg cttctggagg caccttcaac agtcatgcca tcggctgggt gcgacaggcc 120 cctggacaag gccttgagtg gatgggaagg atcgtcccta tccggaagac cacaacttac 180 gcaccgcagt tacagggcag actcacgctg accgcggaca catccacgag cacactgtac 240 atggaactga gtagcctgcg atccgaggac tcggcccggt attactgtgc gagagtcatt 300 ctgtctggga ggggctttga catctggggc cagggatccc tggtcgccgt ctcctcag 358 <210> 9155 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9155 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9156 <211> 361 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9156 gaggtgcagt tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt catctttagt aacttttgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atacagcaag atggaagtga gaaatactat 180 gtggactctg tgaagggccg attcaccatc tccacagacc tcgccaagaa ctcactgtat 240 ctgcaaatga acagcctgag agccgaagac acggctgtgt attactgtgc gagacaacac 300 ggtgactacg actggtactt tgactactgg ggccagggaa ccctggtcac cgtctcctca 360 g 361 <210> 9157 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9157 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9158 <211> 361 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9158 gaggtgcagt tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt catctttagt aacttttgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atacagcaag atggaagtga gaaatactat 180 gtggactctg tgaagggccg attcaccatc tccacagacc tcgccaagaa ctcactgtat 240 ctgcaaatga acagcctgag agccgaagac acggctgtgt attactgtgc gagacaacac 300 ggtgactacg actggtactt tgactactgg ggccagggaa ccctggtcac cgtctcctca 360 g 361 <210> 9159 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9159 gacatccaga tgacccagtc tccatcctca ctgtctgcct ctgtaggaga cagagtcacc 60 atcacttgtc gggcgagtca ggacattaac aattatttag cctggtttca gcagaaacca 120 ggtaaagccc ctaagtccct gatctattct gcgtccagtt tgcaaagtgg ggtcccatcg 180 aggttcagcg gcagtggatc tgggacagat ttcactctca ccatcagcag cctgcagcct 240 gaagattttg caacttatta ttgccaacag tatcgtagtt accctcggac ttttggccag 300 gggaccaagc tggagatcaa ac 322 <210> 9160 <211> 373 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9160 gaggtgcagc tgttggagtc tgggggaggc ttggtacagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt cacctttagc agctatgccg tgtactgggt ccgccaggct 120 ccagggaagg ggctggagtg cgtctcattt attagtggtg gtggtgaaac cacagactac 180 gcagactccg tgaagggccg gttcaccatc tccagagaca attccaagaa cacgttgtat 240 ctgcaaatga acggcctgag agccgaggac acggccgtat attactgtgc gaaatccccg 300 gacgcaacat ttctgtggtt cggggagccc ttcggctact ggggccaggg aaccctggtc 360 accgtctcct cag 373 <210> 9161 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9161 gaaattgtgt tgacgcagtc tccaggcacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtga gagtgtcagt agtaactact tagcctggta ccagcagaag 120 cctggccagg ctcccaggct cctcatctac gatgcatcca gcagggccac tggcatccca 180 gacaggttca gtggcagtgg gtctgggaca gacttcactc tcaccatcag caaactggag 240 cctgaagatt ttgcagtata ttactgtcag cagtatgctc gggccccgga caccttcgcc 300 caagggacac gactggagat taaac 325 <210> 9162 <211> 364 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9162 caggtgcagc tggtggagtc tgggggaggc gtggtccagc ctgggaggtc cctgagactc 60 tcctgtgcag cctctggatt caccttcagt agctatgcta tgcactgggt ccgccaggct 120 ccaggcaagg ggctggagtg ggtggcagtt atatcatatg atggaagcaa taaatactac 180 gcagactccg tgaagggccg attcaccatc tccagagaca attccaagaa cacgctgtat 240 ctgcaaatga acagcctgag agctgaggac acggctgtgt attactgtgc gagagatcct 300 aacccaatgg ttttggccta ctttgactac tggggccagg gaaccctggt caccgtctcc 360 tcag 364 <210> 9163 <211> 331 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9163 cagactgtgg tgacccagga gccatcgttc tcagtgtccc ctggagggac agtcacactc 60 acttgtggct tgagctctgg ctcagtctct actagttact accccagctg gtaccagcag 120 accccaggcc aggctccacg cacgctcatc tacagcacaa acactcgctc ttctggggtc 180 cctgatcgct tctctggctc catccttggg aacaaagctg ccctcaccat cacgggggcc 240 caggcagatg atgaatctga ttattactgt gtgctgtata tgggtagtgg catttgggtg 300 ttcggcggag ggaccaagct gaccgtccta g 331 <210> 9164 <211> 373 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9164 gaggtgcagc tgttggagtc tgggggaggc ttggtacagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt cacctttagc agctatgccg tgtactgggt ccgccaggct 120 ccagggaagg ggctggagtg cgtctcattt attagtggtg gtggtgaaac cacagactac 180 gcagactccg tgaagggccg gttcaccatc tccagagaca attccaagaa cacgttgtat 240 ctgcaaatga acggcctgag agccgaggac acggccgtat attactgtgc gaaatccccg 300 gacgcaacat ttctgtggtt cggggagccc ttcggctact ggggccaggg aaccctggtc 360 accgtctcct cag 373 <210> 9165 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9165 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9166 <211> 359 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9166 caggtgcagc tggtggagtc tgggggaggc gtggtccagc ctgggaggtc cctgagactc 60 tcgtgtgcag cctctggttt taacctcagc aactatgcta tgcactgggt ccgccaggca 120 tcaggcaagg ggctggagtg ggtgtcactt atatcatacg atggaagtat taaatattac 180 acagactccg tgaagggccg attcaccgtc tccggggaca attccaagaa cacactgttt 240 ctgcaaatga acagcctgcg acctgacgac tcggctcttt attactgtgt gaggggcggt 300 gtcagtggcc caaattcttt tgatatgtgg ggccaaggga caacggtcac cgtctcttc 359 <210> 9167 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9167 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9168 <211> 352 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9168 gaggtgcagc tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgacactc 60 tcctgtgcag cctctggttt gaccattaga aactattgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atggaagaag atggaagtga gaaaaactat 180 gtggactctg tgaagggccg attcatcatc tccagagacg acgccaagaa ctcactatat 240 ctacaaatga acagcctgag agccgaggac acggctgtat attactgtac gagagatccc 300 ggtcccgggg atttttcgtg gggccaggga accgtggtaa ccgtctcctc ag 352 <210> 9169 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9169 gaaatagtgt tgacgcagtc tccagccacc ctgtctgtgt ctccagggga aagggtcacc 60 ctctcctgca gggccagtca gactgtaaac aacaacttaa actggctcca gcacaaaccg 120 ggccaggctc ccaggctcgt catcattggt acatctacca gggcctctgg tgtcccagcc 180 aggttcagtg gcagtgggtc ggggacagag ttcactctca ccatcagcag cctgcagtct 240 gaggattatg caatttatta ctgtcaacag tattatgagt ggcctccgat cacctacggc 300 caagggacac gactggagat ta 322 <210> 9170 <211> 372 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9170 caagtgcagc tccagcagtc gggcccagga ctggtgaggc cttcggggac cctgtccctc 60 acgtgcggtg tctctggtgg ctccatcagc agtcctaatt ggtggagttg ggtccgccag 120 gccccaggga agggactgga gtggattggc gaagtctatc ctactgggaa cacctactac 180 aacccgtccc tcaagagtcg agtcaccatt tcaatagagg agtcgaagaa cgagttctcc 240 ctgaacttga gctctgtgac cgccgcagac atgggcattt attactgtgc gagaggcgtc 300 gtgggagcaa gcgacttcta ttattacggt atggacgtct ggggccaagg gaccgcggtc 360 accgtctcct ca 372 <210> 9171 <211> 340 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9171 gagatcgtga tgacccagtc tccagactcc ctgactgtgt ctctgggcga gagggccacc 60 atcagctgca agtccagcca gagtctttta tacagttcca acaataggga ctacttagct 120 tggtaccaac agaaagcagg tcagcctcct aagttgctct tttactgggc atctacccgg 180 gaatccgggg tccctgaccg attcggtggc agcgggtctg ggacacattt cactctcacc 240 atctacaacc tgcagcctga agatgtggca gtttatttct gtcagcagta ttttagtcct 300 ccgtatactt ttggccaggg gaccaagctg gagatcaaac 340 <210> 9172 <211> 362 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9172 caggtgcagc tgcaggagtc gggcccagga ctggtgaagc cttcacagac cctgtccctc 60 aactgctctg tctctggaga ctccatcagc agaagtgatt atcactggag ttggatccgc 120 cagcacccgg gaaagggcct ggagtggatt ggctatatat ataataatgg cgacacatat 180 tataatccgt ccctcaagag tcgtgttacc atgtcagtag acacgtctaa gaacgagttc 240 tccctgaagc tgacctctgt gactgccgcg gacacggccg tctattactg tgcgagagac 300 ggttacgctg gtaactccga ggctcttgac tactggggcc agggaaccct ggtcaccgtc 360 tc 362 <210> 9173 <211> 328 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9173 gaaattgtgt tgacacagtc tccagcctcc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttacc aactacttag cctggtacca acagagacct 120 ggccaggctc ccaggctcct catctatcaa acatccaaca gggccactgg catcccagcc 180 aggttcagtg gcagtgggtc tgggacagac ttcacactca ccatcagcag cctagagcct 240 gaagattttg cattttatta ctgtcagcag cgcagccacc ggcccggggg gatcacgttc 300 ggccaaggga cacgactgga gattaaac 328 <210> 9174 <211> 361 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9174 gaggtgcagt tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt catctttagt aacttttgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atacagcaag atggaagtga gaaatactat 180 gtggactctg tgaagggccg attcaccatc tccacagacc tcgccaagaa ctcactgtat 240 ctgcaaatga acagcctgag agccgaagac acggctgtgt attactgtgc gagacaacac 300 ggtgactacg actggtactt tgactactgg ggccagggaa ccctggtcac cgtctcctca 360 g 361 <210> 9175 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9175 gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc 60 atcacttgcc aggcgagtca ggacattagc aactatttaa attggtatca gcagaaacca 120 gggaaagccc ctaagctcct gatctacgat gcatccaatt tggaaacagg ggtcccatca 180 aggttcagcg gcagtggatc tgggacagat tttactttca ccatcagcag cctgcagcct 240 gaagatattg caacatatta ctgtcaacag tatgataatc tccctctcac tttcggccct 300 gggaccaaag tggatatcaa ac 322 <210> 9176 <211> 361 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9176 gaggtgcagt tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt catctttagt aacttttgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atacagcaag atggaagtga gaaatactat 180 gtggactctg tgaagggccg attcaccatc tccacagacc tcgccaagaa ctcactgtat 240 ctgcaaatga acagcctgag agccgaagac acggctgtgt attactgtgc gagacaacac 300 ggtgactacg actggtactt tgactactgg ggccagggaa ccctggtcac cgtctcctca 360 g 361 <210> 9177 <211> 340 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9177 gagatcgtga tgacccagtc tccagactcc ctgactgtgt ctctgggcga gagggccacc 60 atcagctgca agtccagcca gagtctttta tacagttcca acaataggga ctacttagct 120 tggtaccaac agaaagcagg tcagcctcct aagttgctct tttactgggc atctacccgg 180 gaatccgggg tccctgaccg attcggtggc agcgggtctg ggacacattt cactctcacc 240 atctacaacc tgcagcctga agatgtggca gtttatttct gtcagcagta ttttagtcct 300 ccgtatactt ttggccaggg gaccaagctg gagatcaaac 340 <210> 9178 <211> 367 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9178 gaggtgcaat tagtggagtc tgggggaggc ctggtcaagc ctggggagtc cctgagactc 60 tcctgtgcgg cctctaaatt caccttcagt acctatcata tgaactggat tcgccaggct 120 ccaggaaagg ggctagagtg ggtctcagcc atcagtgctg acagtacggt cacaacatat 180 gcagactcag tgaggggccg attcatcatt tctagagaca acgacaagaa ttcactgtat 240 ctgcaaatga atggcctgag agtggacgac ctggctgtat attactgtgc gagggggcgt 300 gcgcgtggta gtgatcatac tggatttgac tcctggggcc agggaaccct ggtcaccgtc 360 tcctcag 367 <210> 9179 <211> 340 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9179 gatattgtga tgactcagtc tccactctcc ctgtccgtca cccctggaga gccggcctcc 60 atctcctgca ggtcaagtca gagcctcctg catcgtaatg gatacaacat attggattgg 120 tacctgcaga agccagggca gtctccacaa ctcctgatct atttgggttc taatcgggcc 180 tccggggtcc ctgacaggtt cagtggcagt ggatcgggca cggactttac attgaaaatc 240 agcagagtgg aggctgagga tgttggggtt tactactgca tgcaaggtct acagactcct 300 ccgtacactt ttggccaggg gaccaagctg gagatcaaac 340 <210> 9180 <211> 361 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9180 gaggtgcagt tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt catctttagt aacttttgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atacagcaag atggaagtga gaaatactat 180 gtggactctg tgaagggccg attcaccatc tccacagacc tcgccaagaa ctcactgtat 240 ctgcaaatga acagcctgag agccgaagac acggctgtgt attactgtgc gagacaacac 300 ggtgactacg actggtactt tgactactgg ggccagggaa ccctggtcac cgtctcctca 360 g 361 <210> 9181 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9181 gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc 60 atcacttgcc gggcaagtca gagcattacc acctatttaa attggtatca gcagaaagca 120 gggaaagccc ctaacctcct gatctatgct ccatccaatt tgcaaagtgg ggtcccatca 180 agattcagtg gcagtggatc tgggacagat ttcactctca ccatcagcag tctgcaacct 240 gaagattttg gaacttacta ctgtcagcag agttacagta gtccgttcac tttcggccct 300 gggaccaaag tggatatcaa ac 322 <210> 9182 <211> 361 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9182 gaggtgcagt tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt catctttagt aacttttgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atacagcaag atggaagtga gaaatactat 180 gtggactctg tgaagggccg attcaccatc tccacagacc tcgccaagaa ctcactgtat 240 ctgcaaatga acagcctgag agccgaagac acggctgtgt attactgtgc gagacaacac 300 ggtgactacg actggtactt tgactactgg ggccagggaa ccctggtcac cgtctcctca 360 g 361 <210> 9183 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9183 gaaatagtgt tgacgcagtc tccagccacc ctgtctgtgt ctccagggga aagggtcacc 60 ctctcctgca gggccagtca gactgtaaac aacaacttaa actggctcca gcacaaaccg 120 ggccaggctc ccaggctcgt catcattggt acatctacca gggcctctgg tgtcccagcc 180 aggttcagtg gcagtgggtc ggggacagag ttcactctca ccatcagcag cctgcagtct 240 gaggattatg caatttatta ctgtcaacag tattatgagt ggcctccgat cacctacggc 300 caagggacac gactggagat ta 322 <210> 9184 <211> 372 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9184 caagtgcagc tccagcagtc gggcccagga ctggtgaggc cttcggggac cctgtccctc 60 acgtgcggtg tctctggtgg ctccatcagc agtcctaatt ggtggagttg ggtccgccag 120 gccccaggga agggactgga gtggattggc gaagtctatc ctactgggaa cacctactac 180 aacccgtccc tcaagagtcg agtcaccatt tcaatagagg agtcgaagaa cgagttctcc 240 ctgaacttga gctctgtgac cgccgcagac atgggcattt attactgtgc gagaggcgtc 300 gtgggagcaa gcgacttcta ttattacggt atggacgtct ggggccaagg gaccgcggtc 360 accgtctcct ca 372 <210> 9185 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9185 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9186 <211> 337 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9186 caggtgcagc tgcaggagtc gggcccagga ctggtgaagc cttcggagac cctgtccctc 60 acctgcactg tctctggtgg ctccatcagt agttactact ggagctggat ccggcagccc 120 ccagggaagg gactggagta cattggctat atctattaca gtgggagcac caactacaac 180 ccctccctca agagtcgagt caccatatca gtagacacgt ccaagaacca gttatccctg 240 aagctgaggt ctgtgaccgc tgcggacacg gccgtgtatt actgtgcgag ggggtttgac 300 tattggggcc agggaaccct ggtcaccgtc tcctcag 337 <210> 9187 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9187 gaaattgtgt tgacgcagtc tccaggcacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttagc agcagctact tagcctggta ccagcagaaa 120 cctggccagg ctcccaggct cctcatctat ggtacatcca gcagggccac tggcatccca 180 gacaggttca gtggcagtgg gtctgggaca gacttcactc tcaccatcag cagactggag 240 cctgaagatt ttgcagtgtt ttactgtcag cagtatggta actctccgtg gacgttcggc 300 caagggacca aggtggaaat caaac 325 <210> 9188 <211> 352 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9188 gaggtgcagc tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgacactc 60 tcctgtgcag cctctggttt gaccattaga aactattgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atggaagaag atggaagtga gaaaaactat 180 gtggactctg tgaagggccg attcatcatc tccagagacg acgccaagaa ctcactatat 240 ctacaaatga acagcctgag agccgaggac acggctgtat attactgtac gagagatccc 300 ggtcccgggg atttttcgtg gggccaggga accgtggtaa ccgtctcctc ag 352 <210> 9189 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9189 gaaattgtgt tgacacagtc tccagccacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttagc agctacttag cctggtacca acagaaacct 120 ggccaggctc ccaggctcct catttttgat gcatccaaca gggccactgg catcccagcc 180 aggttcagtg gcagtgggtc tgggacagac ttcactctca ccatcagcag cctagagcct 240 gaagattttg cagtttattt ctgtcagcag cgtagcagct ggcaggggat cactttcggc 300 ggagggacca aggtggagat caaac 325 <210> 9190 <211> 361 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9190 gaggtgcagt tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt catctttagt aacttttgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atacagcaag atggaagtga gaaatactat 180 gtggactctg tgaagggccg attcaccatc tccacagacc tcgccaagaa ctcactgtat 240 ctgcaaatga acagcctgag agccgaagac acggctgtgt attactgtgc gagacaacac 300 ggtgactacg actggtactt tgactactgg ggccagggaa ccctggtcac cgtctcctca 360 g 361 <210> 9191 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9191 gaaattgtgt tgacacagtc tccagccacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttagc agctacttag cctggtacca acagaaacct 120 ggccaggctc ccaggctcct catttttgat gcatccaaca gggccactgg catcccagcc 180 aggttcagtg gcagtgggtc tgggacagac ttcactctca ccatcagcag cctagagcct 240 gaagattttg cagtttattt ctgtcagcag cgtagcagct ggcaggggat cactttcggc 300 ggagggacca aggtggagat caaac 325 <210> 9192 <211> 372 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9192 caagtgcagc tccagcagtc gggcccagga ctggtgaggc cttcggggac cctgtccctc 60 acgtgcggtg tctctggtgg ctccatcagc agtcctaatt ggtggagttg ggtccgccag 120 gccccaggga agggactgga gtggattggc gaagtctatc ctactgggaa cacctactac 180 aacccgtccc tcaagagtcg agtcaccatt tcaatagagg agtcgaagaa cgagttctcc 240 ctgaacttga gctctgtgac cgccgcagac atgggcattt attactgtgc gagaggcgtc 300 gtgggagcaa gcgacttcta ttattacggt atggacgtct ggggccaagg gaccgcggtc 360 accgtctcct ca 372 <210> 9193 <211> 319 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9193 gaaattgtgt tgacacagtc tccagccacc ccgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttagc agctacttag cctggtacca acagaaacct 120 ggccaggctc ccaggctcct catttttgat gcatccaaca gggccactgg catcccagcc 180 aggttcagtg gcagtgggtc tgggacagac ttcactctca ccatcagcag cctggagtct 240 gaagattttg gaacttatta ctgtcagcag tataatcact ggcggacgtt cggccaaggg 300 accaaggtgg aaatcaaac 319 <210> 9194 <211> 352 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9194 gaggtgcagc tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgacactc 60 tcctgtgcag cctctggttt gaccattaga aactattgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atggaagaag atggaagtga gaaaaactat 180 gtggactctg tgaagggccg attcatcatc tccagagacg acgccaagaa ctcactatat 240 ctacaaatga acagcctgag agccgaggac acggctgtat attactgtac gagagatccc 300 ggtcccgggg atttttcgtg gggccaggga accgtggtaa ccgtctcctc ag 352 <210> 9195 <211> 340 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9195 gagatcgtga tgacccagtc tccagactcc ctgactgtgt ctctgggcga gagggccacc 60 atcagctgca agtccagcca gagtctttta tacagttcca acaataggga ctacttagct 120 tggtaccaac agaaagcagg tcagcctcct aagttgctct tttactgggc atctacccgg 180 gaatccgggg tccctgaccg attcggtggc agcgggtctg ggacacattt cactctcacc 240 atctacaacc tgcagcctga agatgtggca gtttatttct gtcagcagta ttttagtcct 300 ccgtatactt ttggccaggg gaccaagctg gagatcaaac 340 <210> 9196 <211> 361 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9196 gaggtgcagt tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt catctttagt aacttttgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atacagcaag atggaagtga gaaatactat 180 gtggactctg tgaagggccg attcaccatc tccacagacc tcgccaagaa ctcactgtat 240 ctgcaaatga acagcctgag agccgaagac acggctgtgt attactgtgc gagacaacac 300 ggtgactacg actggtactt tgactactgg ggccagggaa ccctggtcac cgtctcctca 360 g 361 <210> 9197 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9197 gaaattgtgt tgacgcagtc tccaggcacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtga gagtgtcagt agtaactact tagcctggta ccagcagaag 120 cctggccagg ctcccaggct cctcatctac gatgcatcca gcagggccac tggcatccca 180 gacaggttca gtggcagtgg gtctgggaca gacttcactc tcaccatcag caaactggag 240 cctgaagatt ttgcagtata ttactgtcag cagtatgctc gggccccgga caccttcgcc 300 caagggacac gactggagat taaac 325 <210> 9198 <211> 381 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9198 caaatgcagc tggtgcagtc tggggctgag gtgaagaagc ctgggtcctc ggtgaaggtc 60 tcctgcaagg cttctggagg caccttcatc aattatgcta tcaactgggt gcgacaggcc 120 cctggacaac gacttgagta catgggaggg atcatccctc ttcttggtgt tgcaaactac 180 acacagcgat tccagggcag agtcacgatg accgcggaca gatctacgag cacagcctac 240 atggagctga gtaatctggc aattgaagac acggccgtgt attactgtgc gagagagtat 300 agcagcagcc ggcccttatt ttacacctac aactacggta tggacgtctg gggccaaggg 360 accacggtca ccgtctcctc a 381 <210> 9199 <211> 337 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9199 gatattgtga tgacccagac tccactctct ctgtccgtca cccctggaca gccggcctcc 60 atctcctgca agtctagtca gggcctcctg catggtgatg ggaagaccta tttgtattgg 120 ttcttgcaga aggcaggcca gcctccacaa ctcctgatct atgaagtttc aaaccgcttc 180 tccggagtgc cagatagatt cagcggcagc gggtcaggga cagatttcac actgaaaatc 240 agccgggtgg aggctgagga tgttgggatt tattattgca tgcaaagtgt acaccttccg 300 tacacttttg gccaggggac caagttggag atcaaac 337 <210> 9200 <211> 352 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9200 gaggtgcagc tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgacactc 60 tcctgtgcag cctctggttt gaccattaga aactattgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atggaagaag atggaagtga gaaaaactat 180 gtggactctg tgaagggccg attcatcatc tccagagacg acgccaagaa ctcactatat 240 ctacaaatga acagcctgag agccgaggac acggctgtat attactgtac gagagatccc 300 ggtcccgggg atttttcgtg gggccaggga accgtggtaa ccgtctcctc ag 352 <210> 9201 <211> 319 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9201 tcctatgagc tgactcagcc accctcagtg tccgtgtccc caggacagac agccagcatc 60 acctgctctg gagataaatt gggggagaaa tatgcttgct ggtatcagca gaagccaggc 120 cagtcccctg tgttggtcat ttatcaagat accaagcggc cctcagggat ccctgagcga 180 ttctctggct ccaactctgg gaacacagcc acgctgacca tcagcgggac ccaggctgtg 240 gatgaggctg actattactg tcaggcgtgg gactacacca ccgtgatatt cggcggaggg 300 accaagctga ccgtcctag 319 <210> 9202 <211> 352 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9202 gaggtgcagc tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgacactc 60 tcctgtgcag cctctggttt gaccattaga aactattgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atggaagaag atggaagtga gaaaaactat 180 gtggactctg tgaagggccg attcatcatc tccagagacg acgccaagaa ctcactatat 240 ctacaaatga acagcctgag agccgaggac acggctgtat attactgtac gagagatccc 300 ggtcccgggg atttttcgtg gggccaggga accgtggtaa ccgtctcctc ag 352 <210> 9203 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9203 gaaattgtgt tgacgcagtc tccaggcacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttagc agcagctact tagcctggta ccagcagaaa 120 cctggccagg ctcccaggct cctcatctat ggtgcatcca gcagggccac tggcatccca 180 gacaggttca gtggcagtgg gtctgggaca gacttcactc tcaccatcag cagactggag 240 cctgaagatt ttgcagtgta ttactgtcag cagtatggta gctcttacac ttttggccag 300 gggaccaagc tggagatcaa ac 322 <210> 9204 <211> 352 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9204 gaggtgcagc tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgacactc 60 tcctgtgcag cctctggttt gaccattaga aactattgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atggaagaag atggaagtga gaaaaactat 180 gtggactctg tgaagggccg attcatcatc tccagagacg acgccaagaa ctcactatat 240 ctacaaatga acagcctgag agccgaggac acggctgtat attactgtac gagagatccc 300 ggtcccgggg atttttcgtg gggccaggga accgtggtaa ccgtctcctc ag 352 <210> 9205 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9205 gaaattgtgt tgacacagtc tccagccacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttagc agctacttag cctggtacca acagaaacct 120 ggccaggctc ccaggctcct catttttgat gcatccaaca gggccactgg catcccagcc 180 aggttcagtg gcagtgggtc tgggacagac ttcactctca ccatcagcag cctgcagcct 240 gaagattttg caacttatta ttgccaacag tatcgtagtt accctcggac ttttggccag 300 gggaccaagc tggagatcaa ac 322 <210> 9206 <211> 352 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9206 gaggtgcagc tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgacactc 60 tcctgtgcag cctctggttt gaccattaga aactattgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atggaagaag atggaagtga gaaaaactat 180 gtggactctg tgaagggccg attcatcatc tccagagacg acgccaagaa ctcactatat 240 ctacaaatga acagcctgag agccgaggac acggctgtat attactgtac gagagatccc 300 ggtcccgggg atttttcgtg gggccaggga accgtggtaa ccgtctcctc ag 352 <210> 9207 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9207 gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc 60 atcacttgcc gggcaagtca gagcattacc acctatttaa attggtatca gcagaaagca 120 gggaaagccc ctaacctcct gatctatgct ccatccaatt tgcaaagtgg ggtcccatca 180 agattcagtg gcagtggatc tgggacagat ttcactctca ccatcagcag tctgcaacct 240 gaagattttg gaacttacta ctgtcagcag agttacagta gtccgttcac tttcggccct 300 gggaccaaag tggatatcaa ac 322 <210> 9208 <211> 382 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9208 caggtgcagc tggagcagtc tggggctgag gtgaagaggc ctgggtcttc ggtgaaggtc 60 tcctgcaagg gtgatgggga cacattcagc acatatgcca tcacctgggt gcgacaggcc 120 cctggacaag ggcttgagtg gatggggagg atcatccctg gccttgacct ggtggataat 180 caacagaagt ttcaggacag actgacaatt accgcggaca aatccacgac cacagcctac 240 atggagctga gaagcctcag atctgaagac acggccgtat attattgtgc gagaggtaga 300 cgttacgatt ttttggatgg tcaatatacg tcatggtact tcgacatttg gggccgtggc 360 accctggtca ctgtctcctc ag 382 <210> 9209 <211> 337 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9209 aatattgtga tgactcagtc tccactctcc ctgcccgtca cccctggaga gccggcctcc 60 atgtcctgca ggtctaatca gagcctcctg tatggtaatg gatacaacta tttggattgg 120 tacctgcaga gaccagggca gtctccacag ctcctaatct ttttgggttc taatcgggcc 180 tccggggtcc ctgacaggtt cagtggcagt ggatcaggca cagattttac actgaaaatc 240 aacagagtgg aggctgagga tgtgggaatt tattactgca tgcaaggtca agagaatcct 300 ccaacttttg gccctgggac caaagtggag atcaaac 337 <210> 9210 <211> 373 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9210 gaggtgcagc tgttggagtc tgggggaggc ttggtacagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt cacctttagc agctatgccg tgtactgggt ccgccaggct 120 ccagggaagg ggctggagtg cgtctcattt attagtggtg gtggtgaaac cacagactac 180 gcagactccg tgaagggccg gttcaccatc tccagagaca attccaagaa cacgttgtat 240 ctgcaaatga acggcctgag agccgaggac acggccgtat attactgtgc gaaatccccg 300 gacgcaacat ttctgtggtt cggggagccc ttcggctact ggggccaggg aaccctggtc 360 accgtctcct cag 373 <210> 9211 <211> 319 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9211 gaaatagtga tgacgcagtc tccagccacc ctgtctgtgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttagc agcaacttag cctggtacca gcagaaacct 120 ggccaggctc ccaggctcct catctatggt gcatccacca gggccactgg tatcccagcc 180 aggttcagtg gcagtgggtc tgggacagac ttcactctca ccatcagcag cctgcagtct 240 gaagattttg cagtttatta ctgtcagcag tataataact ggcggacgtt cggccaaggg 300 accaaggtgg aaatcaaac 319 <210> 9212 <211> 354 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9212 cagatgcaac tggtgcagag cgggaccgag gtgaaaaaac ccggcgagtc cttgaagatt 60 agttgcaaag gttcaggtta tggattcatt acctactgga taggatgggt aagacaaatg 120 ccaggtaaag gtttggagtg gatggggata atataccctg gggattctga gacaagatac 180 tcccccagct tccagggtca ggtaactata tctgcagata aaagtataaa cactgcctat 240 cttcagtggt cctcactgaa agcatctgac actgctatct actactgtgc cggaggtagt 300 ggcatatcaa ctccaatgga cgtatggggt caagggacaa ctgtcaccgt ctcc 354 <210> 9213 <211> 258 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9213 tctgtactct acagcagcat caataaaaat tacctcgcat ggtatcagca aaagccagga 60 caacccccaa aacttctcat atattgggca agtacacggg agtctggcgt ccccgatagg 120 ttttctggta gtgggagtgg tactgacttt acccttacca tatcatcact tcaagccgag 180 gatgtcgctg tgtactactg ccaacaatat tattcaaccc cttatacatt cggccagggc 240 acaaaggtag aaattaaa 258 <210> 9214 <211> 375 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9214 caggtgcagc tgcaggagtc gggcccagga ctggtgaagc cttcacagac cctgtccctc 60 acctgcactg tctctggtgg ctccatcagc agtggtagtc actactggag ctggattcgg 120 cagcccgccg gaaagggact ggagtgggtc gggcgtatct ataccagtgg gagcaccaac 180 tacaacccct ccctcgagcg tcgagtcacc atatcactag gcacgtccaa gaaccagttc 240 taccttgatc tgacctctgt gaccgccgca gacacggccg tgtattactg tgcgagagat 300 tccttgagtg gttcttacca ctactactac ggtatggacg tctggggcca agggacctcg 360 gtcaccgtct cctca 375 <210> 9215 <211> 331 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9215 cagtctgtgc tgactcagcc accctcagcg tctgggaccc ccgggcagag ggtcaccatc 60 tcttgttctg gaagcagttc caacatcgga agtaattatg tttactggta ccagcacctc 120 ccaggaacgg cccccaaact cctcatctat aggaattatc agcggccctc aggggtccct 180 gaccgattct ctggctccaa gtctggcacc tcagcctccc tggccatcag tgggctccgg 240 tccgaggatg agggtgatta ttattgtgca gtttgggatg acagcctgag tggttgggtg 300 ttcggcggag ggaccaagct gaccgtccta g 331 <210> 9216 <211> 355 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9216 caggtgcaac tggtggagtc tgggggaggc gtggtccagc ctgggaggtc cctgagactc 60 tcctgtgcag cctctggatt caccttcatt agctatacta tgcactgggt ccgccaggct 120 ccaggcaagg ggctggagtg ggtggcactt atatcatatg atggatacaa taagtactat 180 gcagactccg tgaagggccg atttaccatc tccagagaca attccaagaa cacgctgtat 240 gtgcaaatga acagcctgag agctgaggac acggctctgt attactgtgc gagagaaggg 300 agcccggagg cctttgacta ctggggccag ggaaccctgg tcaccgtctc ctcag 355 <210> 9217 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9217 gaaatagtgt tgacgcagtc tccagccacc ctgtctgtgt ctccagggga aagggtcacc 60 ctctcctgca gggccagtca gactgtaaac aacaacttaa actggctcca gcacaaaccg 120 ggccaggctc ccaggctcgt catcattggt acatctacca gggcctctgg tgtcccagcc 180 aggttcagtg gcagtgggtc ggggacagag ttcactctca ccatcagcag cctgcagtct 240 gaggattatg caatttatta ctgtcaacag tattatgagt ggcctccgat cacctacggc 300 caagggacac gactggagat ta 322 <210> 9218 <211> 372 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9218 gaggtgcagc tggtggagtc tgggggaggc ttggtccagc cgggggggtc ccggagactc 60 tcctgtggag cctctggatt cacctttact aatcattgga tgagctgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccagc ataaagcaag atggagctga gaaatactat 180 gtggactatc tgaagggccg attcaccatc tccagagaca acgccaagaa ttcactgtat 240 ctgcaaatga acagcctgag agtcgaggac acggctgttt attactgtgc gagacgtatc 300 acgatggcac tggctggttg gggttggggt atggacgtct ggggccaagg gaccacggtc 360 agagtctcct ca 372 <210> 9219 <211> 337 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9219 gatattgtga tgactcagtc tccactctcc ctgcccgtca cccctggaga gccggcctcc 60 atctcctgca ggtctagtcg gagtctcttg tctaggaatg gatacaacta tttggattgg 120 tacctgcaga ggccagggca gtctccacag ctcgtgatct atttgggttc taatcgggcc 180 tccggggtcc ctgacaggtt cagtggcagt ggatcaggca cagattttac actgaaaatc 240 agcagagtgg aggctgagga tgttgggctt tattactgca tgcaagctat gcaagctcct 300 ctcactttcg gcccggggac caaagtggaa atcaaac 337 <210> 9220 <211> 378 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9220 caggtgcagc tggtacaatc tgggtctgaa ttgaagaagc ctggggcctc agtgaaggtt 60 tcctgcaaga cttctggata caccttcact agttatgcta taaattgggt gcgacaggcc 120 cctggacaag ggcttgagtg gatcggatgg atcaacatca acactgggaa cccaacgtat 180 gcccagggct tcacaggacg ggttgacttc tccttggaca cctctgtcag cacggcatat 240 ctgcagatca gaagcctaaa ggctgaggac actgctgtgt attactgtgc gagagatcgg 300 ggtatagcag ctcgtcgggg atactactac tacggtatgg acgtctgggg ccaagggacc 360 acggtcaccg tctcctca 378 <210> 9221 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9221 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9222 <211> 382 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9222 caggtgcagc tggagcagtc tggggctgag gtgaagaggc ctgggtcttc ggtgaaggtc 60 tcctgcaagg gtgatgggga cacattcagc acatatgcca tcacctgggt gcgacaggcc 120 cctggacaag ggcttgagtg gatggggagg atcatccctg gccttgacct ggtggataat 180 caacagaagt ttcaggacag actgacaatt accgcggaca aatccacgac cacagcctac 240 atggagctga gaagcctcag atctgaagac acggccgtat attattgtgc gagaggtaga 300 cgttacgatt ttttggatgg tcaatatacg tcatggtact tcgacatttg gggccgtggc 360 accctggtca ctgtctcctc ag 382 <210> 9223 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9223 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9224 <211> 337 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9224 caggtgcagc tgcaggagtc gggcccagga ctggtgaagc cttcggagac cctgtccctc 60 acctgcactg tctctggtgg ctccatcagt agttactact ggagctggat ccggcagccc 120 ccagggaagg gactggagta cattggctat atctattaca gtgggagcac caactacaac 180 ccctccctca agagtcgagt caccatatca gtagacacgt ccaagaacca gttatccctg 240 aagctgaggt ctgtgaccgc tgcggacacg gccgtgtatt actgtgcgag ggggtttgac 300 tattggggcc agggaaccct ggtcaccgtc tcctcag 337 <210> 9225 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9225 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9226 <211> 364 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9226 caggtgcagc ttcagcagtg gggcgcagga cttttgaagc cttcggaaac cctgtccctc 60 acctgcgctg tccacggtgg gtccttcagt ggtccctact ggacctggat ccgccagtcg 120 ccaagtcagg ggctggagtg gattggagaa atcggtcctc gtgggatcac ctactacagc 180 ccgtccctcg agagtcgagt caccatatca gcagacacgt ccaggaatca gttctccctg 240 aggctgacgt ctgtgaccgc cgcggacacg gctgtctatt actgtgcgag aggcttggtt 300 attggaagaa gcagcctaaa ctttgactct tggggccagg gaaccctggt caccgtctcc 360 tcag 364 <210> 9227 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9227 gaaattgtgt tgacgcagtc tccaggcacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtga gagtgtcagt agtaactact tagcctggta ccagcagaag 120 cctggccagg ctcccaggct cctcatctac gatgcatcca gcagggccac tggcatccca 180 gacaggttca gtggcagtgg gtctgggaca gacttcactc tcaccatcag caaactggag 240 cctgaagatt ttgcagtata ttactgtcag cagtatgctc gggccccgga caccttcgcc 300 caagggacac gactggagat taaac 325 <210> 9228 <211> 358 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9228 gaggtgcaac tggtggaggc tgggggaggc ctggtcaagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt caccttcagt ggctatgcca taaactgggt ccgccaggct 120 ccagggaagg gcctggagtg ggtctcgtcc attagtggga ataataatga tatgtactac 180 gcagactcag tgaagggccg attcaccatc tccagagaca acgccaagag ctcagtgttt 240 ctgcaaatga acagcctgag agtcgaggac acggctatct attactgtgc gagagataac 300 ttagcactgg ctggggagga ctactggggc cagggaaccc tggtcaccgt ctcctcag 358 <210> 9229 <211> 340 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9229 gagatcgtga tgacccagtc tccagactcc ctgactgtgt ctctgggcga gagggccacc 60 atcagctgca agtccagcca gagtctttta tacagttcca acaataggga ctacttagct 120 tggtaccaac agaaagcagg tcagcctcct aagttgctct tttactgggc atctacccgg 180 gaatccgggg tccctgaccg attcggtggc agcgggtctg ggacacattt cactctcacc 240 atctacaacc tgcagcctga agatgtggca gtttatttct gtcagcagta ttttagtcct 300 ccgtatactt ttggccaggg gaccaagctg gagatcaaac 340 <210> 9230 <211> 373 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9230 gaggtgcagc tgttggagtc tgggggaggc ttggtacagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt cacctttagc agctatgccg tgtactgggt ccgccaggct 120 ccagggaagg ggctggagtg cgtctcattt attagtggtg gtggtgaaac cacagactac 180 gcagactccg tgaagggccg gttcaccatc tccagagaca attccaagaa cacgttgtat 240 ctgcaaatga acggcctgag agccgaggac acggccgtat attactgtgc gaaatccccg 300 gacgcaacat ttctgtggtt cggggagccc ttcggctact ggggccaggg aaccctggtc 360 accgtctcct cag 373 <210> 9231 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9231 gaaatagtga tgacgcagtc tccagccacc ctgtctgtgt ctccagggga aagagtcacc 60 ctctcctgca gggccagtca gagtgttagc agcaacgtag cctggtacca gcagaaacct 120 ggccaggctc ccagcctcct catctatggt gcatccacca gggccactgg taccccagcc 180 aggttcagtg gcagtgggtc tgggacaggg ttcactctca ccatcaccag cctgcagtct 240 gaagattttg gagtttatta ctgtcagcaa tataataact ggcgattcac tttcggccct 300 gggaccaaag tggagatcaa ac 322 <210> 9232 <211> 375 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9232 gaggtgcagt tgttggagtc ggggggaggc ttggtgcagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt cgtctttagc gactattcca tgaattgggt ccgcctggct 120 ccaggaaagg ggctggcgtg ggtctctgtt gttggtgttg atgccgtcac caaattctat 180 gaagactccg tgaagggccg gttcaccatt tccagagaca actccaagaa cacgatatat 240 ctgcaaatga acaacctgag agccgaagac acggccgtat atcactgtgc gaaaagtcag 300 ccggtgtctc gcatgggtcg cttcttcgtc ggtttggacg tctggggcca agggaccacg 360 gtcaccgtct cctca 375 <210> 9233 <211> 340 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9233 gagatcgtga tgacccagtc tccagactcc ctgactgtgt ctctgggcga gagggccacc 60 atcagctgca agtccagcca gagtctttta tacagttcca acaataggga ctacttagct 120 tggtaccaac agaaagcagg tcagcctcct aagttgctct tttactgggc atctacccgg 180 gaatccgggg tccctgaccg attcggtggc agcgggtctg ggacacattt cactctcacc 240 atctacaacc tgcagcctga agatgtggca gtttatttct gtcagcagta ttttagtcct 300 ccgtatactt ttggccaggg gaccaagctg gagatcaaac 340 <210> 9234 <211> 367 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9234 gaggtgcagc tggtggagtc tgggggaggc ctggtcaagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt caccttcagt agttatagca tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtctcatcc attagtagta ctagtagtta catatactac 180 gcagactcag tgaagggccg attcaccatc tccagagaca acgccaagaa ctcactgtat 240 ctgcaaatga acagcctgag agccgaggac acggctgtat attactgtgc gagacgtagg 300 gcggcaactg gtacggagtt ctactttgac tactggggcc agggaaccct ggtcaccgtc 360 tcctcag 367 <210> 9235 <211> 331 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9235 cagtctgtgt tgacgcagcc gccctcagtg tctgcggccc caggacagaa ggtcaccatc 60 tcctgctctg gaagcagctc caacattggg aataattatg tatcctggta ccagcagctc 120 ccaggaacag cccccaaact cctcatttat gacaataata agcgaccctc agggattcct 180 gaccgattct ctggctccaa gtctggcacg tcagccaccc tgggcatcac cggactccag 240 actggggacg aggccgatta ttactgcgga acatgggata gcagcctgag tgctgtgcta 300 ttcggcggag ggaccaagct gaccgtccta g 331 <210> 9236 <211> 358 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9236 caggcacacc tggtgcagtc tggggctgag gtgaagaagc ctgggtcctc ggtgaaggtc 60 tcctgcaagg cttctggagg caccttcaac agtcatgcca tcggctgggt gcgacaggcc 120 cctggacaag gccttgagtg gatgggaagg atcgtcccta tccggaagac cacaacttac 180 gcaccgcagt tacagggcag actcacgctg accgcggaca catccacgag cacactgtac 240 atggaactga gtagcctgcg atccgaggac tcggcccggt attactgtgc gagagtcatt 300 ctgtctggga ggggctttga catctggggc cagggatccc tggtcgccgt ctcctcag 358 <210> 9237 <211> 313 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9237 gacatccaaa tgacccaatc tccttccgcc ctggctgcat ctctgggaga cagagtcatc 60 atcacttgcc aggcgagtca cgacattggt cacaatttaa attggtatca gcagagacca 120 ggggaagccc ctcagctcct gatctacgat gtatccaatt tgcaaacagg ggtcccatca 180 aggttcagtg gctttggatt tgggacaaat tttactttca ccatcagcgg cctgcagtct 240 gaagatatcg gaacatatta ctgtcaacag tatgatagta tttttggccc agggaccaag 300 ttggagatca aac 313 <210> 9238 <211> 381 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9238 caggtccagc tggtgcagtc tggggctgag gtgaagaagc ctgggtcctc ggtgaaggtc 60 tcctgcaagg cttctggagg cacctttagc agctatgctt tcagttgggt gcgacaggcc 120 cctggacaag ggcttgagtg gatgggaagg atcatcctta ttcttggtat aacagactac 180 gcaccgaagt tccagggcag agtcacgatt accgcggaca aatccacgag cacagtgtac 240 atggaggtga gcagcctgag atcggacgac acggccgtgt attactgtgc gagagaaagg 300 ccaagagacc cctccagtaa ctacgttgcc tactacgcta tggacgtctg gggccaaggg 360 acctcggtca ccgtctcgtc a 381 <210> 9239 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9239 gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc 60 atcacttgcc gggcaagtca gagcattacc acctatttaa attggtatca gcagaaagca 120 gggaaagccc ctaacctcct gatctatgct ccatccaatt tgcaaagtgg ggtcccatca 180 agattcagtg gcagtggatc tgggacagat ttcactctca ccatcagcag tctgcaacct 240 gaagattttg gaacttacta ctgtcagcag agttacagta gtccgttcac tttcggccct 300 gggaccaaag tggatatcaa ac 322 <210> 9240 <211> 372 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9240 caagtgcagc tccagcagtc gggcccagga ctggtgaggc cttcggggac cctgtccctc 60 acgtgcggtg tctctggtgg ctccatcagc agtcctaatt ggtggagttg ggtccgccag 120 gccccaggga agggactgga gtggattggc gaagtctatc ctactgggaa cacctactac 180 aacccgtccc tcaagagtcg agtcaccatt tcaatagagg agtcgaagaa cgagttctcc 240 ctgaacttga gctctgtgac cgccgcagac atgggcattt attactgtgc gagaggcgtc 300 gtgggagcaa gcgacttcta ttattacggt atggacgtct ggggccaagg gaccgcggtc 360 accgtctcct ca 372 <210> 9241 <211> 321 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9241 gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgttgggga cagagtcacc 60 atcacttgcc gggcaagtga aaccattagt aattttttaa attggtatct ccaacgacca 120 gggaaagccc ctcaggtcct catctattct gcagcccgtt tacaaagtgg ggtcccatca 180 aggttccgtg ccagtggatc tgggacagat ttcactctca ccatcaccag tctgcaactt 240 gaagattttg gagtttatta ctgtcaacag agtttcaata cccctcggac gttcggccaa 300 gggaccaggg tggagatcaa a 321 <210> 9242 <211> 352 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9242 gaggtgcagc tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgacactc 60 tcctgtgcag cctctggttt gaccattaga aactattgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atggaagaag atggaagtga gaaaaactat 180 gtggactctg tgaagggccg attcatcatc tccagagacg acgccaagaa ctcactatat 240 ctacaaatga acagcctgag agccgaggac acggctgtat attactgtac gagagatccc 300 ggtcccgggg atttttcgtg gggccaggga accgtggtaa ccgtctcctc ag 352 <210> 9243 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9243 gaaattgtgt tgacgcagtc tccaggcacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtga gagtgtcagt agtaactact tagcctggta ccagcagaag 120 cctggccagg ctcccaggct cctcatctac gatgcatcca gcagggccac tggcatccca 180 gacaggttca gtggcagtgg gtctgggaca gacttcactc tcaccatcag caaactggag 240 cctgaagatt ttgcagtata ttactgtcag cagtatgctc gggccccgga caccttcgcc 300 caagggacac gactggagat taaac 325 <210> 9244 <211> 376 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9244 caggtgcagc tacagcagtg gggcgcagga ctcttgaagc ctgcggagac cctgtccctc 60 acctgcgctg tccatggtgg gtccttcact gattcctact ggagttggat ccgccagacc 120 cccgggcagg gactggagtg gcttggggaa gtcaatcata gtggaagcac caactacagc 180 ccgtccctca agactcgagt cgccatatca atagacacgt ccaagaacca ggtctccctc 240 aggctgacct ctgtgagcgc cgcggacacg gctgtctatt attgtgcgag aggaatggcc 300 gttcggggga gacagctcta cttactcggg ggctatgacc tctggggcca gggaaccctg 360 gtcaccgtct cctcag 376 <210> 9245 <211> 319 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9245 gaagttgtga tgacgcagtc tccagccacc ctgtctgtgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgtctac atcaacttag cctggtacca gcagaaacct 120 ggccagcctc ccaggctcct catctatggt gcatccacca gggccactgg tatcccagcc 180 aggttcagtg gcagtgggtc tgggacagag ttcactctca ccatcagcag cctggagtct 240 gaagattttg gaacttatta ctgtcagcag tataatcact ggcggacgtt cggccaaggg 300 accaaggtgg aaatcaaac 319 <210> 9246 <211> 355 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9246 tcccagctgc tgcaggagtc gggcccagga ctcgtgaagc cttcggagac cctgtccctc 60 acgtgcactg tatttggtga ctccatctat ggttactact ggacttggat ccggcagccc 120 ccagggaggg gactggagtg gattgggtct gtctatcaca gtggcagcac caactacaac 180 ccctccctca tgagtcgagt caccatatca gtggacacgt ccgagaagca gttctccctg 240 aaggtgactt ctgtgaccgg tgcggacacg gccgtatatt tttgtgcgag agggctggct 300 ggcgggggtt attttgacgc ctggggccag ggaaacctgg tcgccgtctc ctcag 355 <210> 9247 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9247 gacgtccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc 60 atcacttgcc gggcgagtcc gggcattaac acttatttag cctggtatca gcagaagcca 120 gggcaagttc ctgacctcct gatctatggt gcatccacct tgcgatctgg ggtcccgtct 180 cggttcagtg gcagtggatc tgggacagat ttcactctca ccatcagcag cctgcagctt 240 gaagatgttg caacttatta ctgtcaggct tattacgttg gcctcggtac tttcggccaa 300 gggaccaagg tggaaatcaa ac 322 <210> 9248 <211> 358 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9248 gaggtgcaac tggtggagtc tgggggagga gtggtacggc ctggggagtc cctgagactc 60 tcctgtgtag gctctggatt cccctttggt ggctatggca tgagttgggt ccgccaagtt 120 ccagggaagg ggctggagtg ggtctctgga attaattgga gtgctgatcg aagagtttat 180 gcagactttg tgaagggccg attcaccatc tccagagact accccaagaa gtctgtgtcc 240 ttgcaaatgg acaatctcag agccgaggac acggccctct attattgtgc gagagagcgg 300 acctctcgcc gtgactttga cttctggggc cagggaaccc tggtcaccgt ctcctcag 358 <210> 9249 <211> 324 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9249 tcctttgtgc tgactcagcc accctcagtg tcagtggctc caggacagac ggccaggatt 60 ccctgtgcga aaaattatcg tggaagtcag actgtgcact ggtaccagcg gaagccaggc 120 caggcccctg tcttggtcat caattctgat gacgaccggc cctcagggat ctctgagcga 180 ttctctggct ccaactctgg gaacacggcc accctgacca tcagcagggt cgaagccggg 240 gatgaggccg actattattg tcaggtgtgg gatcccagtt ctgatcaagc gctattcgcc 300 ggagggacca cgctgaccgt ccta 324 <210> 9250 <211> 364 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9250 gaggtgcagc tggtggactc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt cacctttact agttattgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac ataaagcaag atggaagtga gaaagactat 180 gtggactctg tgaagggacg attcaccatc tccagagaca acgccaagaa ctcactgtat 240 ctgcaaatga gcagcctgag agccgaggac acggctgtgt attactgtgc gagagatctc 300 ggcagtggct cgtaccacct ctttgactac tggggccagg gaaccctggt caccgtctcc 360 tcag 364 <210> 9251 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9251 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9252 <211> 378 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9252 caggtgcagc tggtacaatc tgggtctgaa ttgaagaagc ctggggcctc agtgaaggtt 60 tcctgcaaga cttctggata caccttcact agttatgcta taaattgggt gcgacaggcc 120 cctggacaag ggcttgagtg gatcggatgg atcaacatca acactgggaa cccaacgtat 180 gcccagggct tcacaggacg ggttgacttc tccttggaca cctctgtcag cacggcatat 240 ctgcagatca gaagcctaaa ggctgaggac actgctgtgt attactgtgc gagagatcgg 300 ggtatagcag ctcgtcgggg atactactac tacggtatgg acgtctgggg ccaagggacc 360 acggtcaccg tctcctca 378 <210> 9253 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9253 gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc 60 atcacttgcc gggcaagtca gagcattacc acctatttaa attggtatca gcagaaagca 120 gggaaagccc ctaacctcct gatctatgct ccatccaatt tgcaaagtgg ggtcccatca 180 agattcagtg gcagtggatc tgggacagat ttcactctca ccatcagcag tctgcaacct 240 gaagattttg gaacttacta ctgtcagcag agttacagta gtccgttcac tttcggccct 300 gggaccaaag tggatatcaa ac 322 <210> 9254 <211> 358 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9254 gaggtgcaac tggtggagtc tgggggagga gtggtacggc ctggggagtc cctgagactc 60 tcctgtgtag gctctggatt cccctttggt ggctatggca tgagttgggt ccgccaagtt 120 ccagggaagg ggctggagtg ggtctctgga attaattgga gtgctgatcg aagagtttat 180 gcagactttg tgaagggccg attcaccatc tccagagact accccaagaa gtctgtgtcc 240 ttgcaaatgg acaatctcag agccgaggac acggccctct attattgtgc gagagagcgg 300 acctctcgcc gtgactttga cttctggggc cagggaaccc tggtcaccgt ctcctcag 358 <210> 9255 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9255 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9256 <211> 364 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9256 gaggtgcagc tggtggactc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt cacctttact agttattgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac ataaagcaag atggaagtga gaaagactat 180 gtggactctg tgaagggacg attcaccatc tccagagaca acgccaagaa ctcactgtat 240 ctgcaaatga gcagcctgag agccgaggac acggctgtgt attactgtgc gagagatctc 300 ggcagtggct cgtaccacct ctttgactac tggggccagg gaaccctggt caccgtctcc 360 tcag 364 <210> 9257 <211> 330 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9257 cagtctgtgt tgacgcagcc gccctcagtg tctgcggccc caggacagaa ggtcaccatc 60 tcctgctctg gaagcagctc caacattggg aataattatg tatcctggta ccagcagctc 120 ccaggaacag cccccaaact cctcatttat gacaataata agcgaccctc agggattcct 180 gaccgattct ctggctccaa gtctggcacg tcagccaccc tgggcatcac cggactccag 240 actggggacg aggccgatta ttactgcgga acatgggata acagcctgag tgcctgggtg 300 ttcggcggag ggaccaagct gaccgtccta 330 <210> 9258 <211> 337 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9258 caggtgcagc tgcaggagtc gggcccagga ctggtgaagc cttcggagac cctgtccctc 60 acctgcactg tctctggtgg ctccatcagt agttactact ggagctggat ccggcagccc 120 ccagggaagg gactggagta cattggctat atctattaca gtgggagcac caactacaac 180 ccctccctca agagtcgagt caccatatca gtagacacgt ccaagaacca gttatccctg 240 aagctgaggt ctgtgaccgc tgcggacacg gccgtgtatt actgtgcgag ggggtttgac 300 tattggggcc agggaaccct ggtcaccgtc tcctcag 337 <210> 9259 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9259 gaaattgtgt tgacacagtc tccagccacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttagc agctacttag cctggtacca acagaaacct 120 ggccaggctc ccaggctcct catttttgat gcatccaaca gggccactgg catcccagcc 180 aggttcagtg gcagtgggtc tgggacagac ttcactctca ccatcagcag cctagagcct 240 gaagattttg cagtttattt ctgtcagcag cgtagcagct ggcaggggat cactttcggc 300 ggagggacca aggtggagat caaac 325 <210> 9260 <211> 373 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9260 caggtgcagc tggtgcaatc tgggtctgag ttgaagaagc ctggggcctc agttaagatt 60 tcctgcaaga cttctggata caatttcact aatcatccta taaattgggt gcgacaggcc 120 cctggacaag ggcttgagtg gatgggatgg atcaacacca acactgggaa cccaacgtat 180 ggccaggcct tcacaggacg atttgtcttc tcctttgaca cctctgtcgg cacggcatat 240 ctgcacatca gcggcctgca gcctggagac actgccttct attactgtgt gagagaggac 300 ctgagactta gacaggtgtg gtggcggtgg ttcgacccct ggggccaggg aaccctggtc 360 accgtctcct cag 373 <210> 9261 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9261 gagatccaga tgacccagtc accatcctcc ctgtctgcct ctgtaggaga cagagtcacc 60 atttcttgtc gggcaagtca gagcgtcggc ggtcatttaa attggtatca gcagaaaccg 120 gggaaagccc ctaaggtcct gatccacgct gcttccagtt tagaaggtgg ggtcccttca 180 cggttcagtg gcagtggatc tgggacagat tacactctca ccatcaccaa ccttcagcct 240 gaagattttg cgacttactt ctgccagcag agtcgcaact cccctgcgac gttcggccaa 300 gggaccaagg tggagatgaa ac 322 <210> 9262 <211> 364 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9262 caggtgcagc tggtggagtc tgggggaggc gtggtccagc ctgggaggtc cctgagactc 60 tcctgtgcag cctctggatt caccttcagt agctatgcta tgcactgggt ccgccaggct 120 ccaggcaagg ggctggagtg ggtggcagtt atatcatatg atggaagcaa taaatactac 180 gcagactccg tgaagggccg attcaccatc tccagagaca attccaagaa cacgctgtat 240 ctgcaaatga acagcctgag agctgaggac acggctgtgt attactgtgc gagaggaaaa 300 ctggggatag tcggtgatgc ttttgatatc tggggccaag ggacaatggt caccgtctct 360 tcag 364 <210> 9263 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9263 gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc 60 atcacttgcc aggcgagtca ggacattagc aactatttaa attggtatca gcagaaacca 120 gggaaagccc ctaagctcct gatctacgat gcatccaatt tggaaacagg ggtcccatca 180 aggttcagtg gaagtggatc tgggacagat tttactttca ccatcagcag cctgcagcct 240 gaagatattg caacatatta ctgtcaacag tatgataatc tccctctcac tttcggccct 300 gggaccaaag tggatatcaa ac 322 <210> 9264 <211> 355 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9264 tcccagctgc tgcaggagtc gggcccagga ctcgtgaagc cttcggagac cctgtccctc 60 acgtgcactg tatttggtga ctccatctat ggttactact ggacttggat ccggcagccc 120 ccagggaggg gactggagtg gattgggtct gtctatcaca gtggcagcac caactacaac 180 ccctccctca tgagtcgagt caccatatca gtggacacgt ccgagaagca gttctccctg 240 aaggtgactt ctgtgaccgg tgcggacacg gccgtatatt tttgtgcgag agggctggct 300 ggcgggggtt attttgacgc ctggggccag ggaaacctgg tcgccgtctc ctcag 355 <210> 9265 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9265 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9266 <211> 382 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9266 caggtgcagc tggagcagtc tggggctgag gtgaagaggc ctgggtcttc ggtgaaggtc 60 tcctgcaagg gtgatgggga cacattcagc acatatgcca tcacctgggt gcgacaggcc 120 cctggacaag ggcttgagtg gatggggagg atcatccctg gccttgacct ggtggataat 180 caacagaagt ttcaggacag actgacaatt accgcggaca aatccacgac cacagcctac 240 atggagctga gaagcctcag atctgaagac acggccgtat attattgtgc gagaggtaga 300 cgttacgatt ttttggatgg tcaatatacg tcatggtact tcgacatttg gggccgtggc 360 accctggtca ctgtctcctc ag 382 <210> 9267 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9267 gaaatagtgt tgacgcagtc tccagccacc ctgtctgtgt ctccagggga aagggtcacc 60 ctctcctgca gggccagtca gactgtaaac aacaacttaa actggctcca gcacaaaccg 120 ggccaggctc ccaggctcgt catcattggt acatctacca gggcctctgg tgtcccagcc 180 aggttcagtg gcagtgggtc ggggacagag ttcactctca ccatcagcag cctgcagtct 240 gaggattatg caatttatta ctgtcaacag tattatgagt ggcctccgat cacctacggc 300 caagggacac gactggagat ta 322 <210> 9268 <211> 366 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9268 gaggtccagc tggtacagtc tggggctgag gtgaagaagc ctggggctac agtgaaaatc 60 tcctgcaagg tttctggata caccttcacc gactactaca tgcactgggt gcaacaggcc 120 cctggaaaag ggcttgagtg gatgggactt gttgatcctg aagatggtga aacaatatac 180 gcagagaagt tccagggcag agtcaccata accgcggaca cgtctacaga cacagcctac 240 atggagctga gcagcctgag atctgaggac acggccgtgt attactgtgc aacagtgtcc 300 aggtggtact actactacta cggtatggac gtctggggcc aagggaccac ggtcaccgtc 360 tcctca 366 <210> 9269 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9269 gaaattgtgt tgacgcagtc tccaggcacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttagc agcagctact tagcctggta ccagcagaaa 120 cctggccagg ctcccaggct cctcatctat ggtgcatcca gcagggccac tggcatccca 180 gacaggttca gtggcagtgg gtctgggaca gacttcactc tcaccatcag cagactggag 240 cctgaagatt ttgcagtgta ttactgtcag cagtatggta gctcttacac ttttggccag 300 gggaccaagc tggagatcaa ac 322 <210> 9270 <211> 359 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9270 caggtgcagc tggtggagtc tgggggaggc gtggtccagc ctgggaggtc cctgagactc 60 tcgtgtgcag cctctggttt taacctcagc aactatgcta tgcactgggt ccgccaggca 120 tcaggcaagg ggctggagtg ggtgtcactt atatcatacg atggaagtat taaatattac 180 acagactccg tgaagggccg attcaccgtc tccggggaca attccaagaa cacactgttt 240 ctgcaaatga acagcctgcg acctgacgac tcggctcttt attactgtgt gaggggcggt 300 gtcagtggcc caaattcttt tgatatgtgg ggccaaggga caacggtcac cgtctcttc 359 <210> 9271 <211> 337 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9271 gatgttgtga tgactcagtc tccactctcc ctgcccgtca cccttggaca gccggcctcc 60 atctcctgca ggtctagtca aagcctcgta tacagtgatg gaaacaccta cgtgaattgg 120 tttcagcaga ggccaggcca atctccaagg cgcctaatct atcaggtttc tatccgggcc 180 tctggggtcc cagacagatt cagcggcagt gggtcaggca ctgatttcgc actgaaaatc 240 agcagggtgg aggctgagga tgttgggatt tattattgca tgcaaggtac acactggccg 300 gtgacgttcg gccaagggac caaggtggaa atcaaac 337 <210> 9272 <211> 375 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9272 gaggtgcagt tgttggagtc ggggggaggc ttggtgcagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt cgtctttagc gactattcca tgaattgggt ccgcctggct 120 ccaggaaagg ggctggcgtg ggtctctgtt gttggtgttg atgccgtcac caaattctat 180 gaagactccg tgaagggccg gttcaccatt tccagagaca actccaagaa cacgatatat 240 ctgcaaatga acaacctgag agccgaagac acggccgtat atcactgtgc gaaaagtcag 300 ccggtgtctc gcatgggtcg cttcttcgtc ggtttggacg tctggggcca agggaccacg 360 gtcaccgtct cctca 375 <210> 9273 <211> 331 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9273 cagtctgccc tgactcagcc tccctccgcg tccgggtctc ctggacagtc agtcaccatc 60 tcctgcactg gaagcagcaa tgacgtcggt cgttataact atgtctcatg gtaccaacat 120 cacccaggca aagcccccag actcatgatt tctgaggtcg ttaagcggcc ctcaggggtc 180 cctgatcgct tctctggctc caagtctggc aacacggcct ccctgaccgt ctctggactc 240 caggctgaag atgaggctga ttattactgc agctcatatg gaggcaacaa cattttacta 300 ttcggcggag ggaccaagct gaccgtccta g 331 <210> 9274 <211> 355 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9274 caggtgcaac tggtggagtc tgggggaggc gtggtccagc ctgggaggtc cctgagactc 60 tcctgtgcag cctctggatt caccttcatt agctatacta tgcactgggt ccgccaggct 120 ccaggcaagg ggctggagtg ggtggcactt atatcatatg atggatacaa taagtactat 180 gcagactccg tgaagggccg atttaccatc tccagagaca attccaagaa cacgctgtat 240 gtgcaaatga acagcctgag agctgaggac acggctctgt attactgtgc gagagaaggg 300 agcccggagg cctttgacta ctggggccag ggaaccctgg tcaccgtctc ctcag 355 <210> 9275 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9275 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9276 <211> 352 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9276 gagatgcagc tggtggagtc cgggggaggc ttagttcagc cgggggggtc cctgagactc 60 tcctgtgcag cctctggatt caccttcagt gactactaca tgtactgggt ccgccaagct 120 ccagggaagg ggctggtgtg ggtctcacgt attaagcctg atgggactgg cacaagttac 180 gcggactccg tgaggggccg attcaccgtc tccagagaca acgccaagaa cacgctgaat 240 ctgcaaatga acagtctgag agccgaggac acggctgtgt attattgtgt ggcctacaac 300 tggaactacg acttctgctg gggccaggga accctggtaa ccgtctccgc ag 352 <210> 9277 <211> 337 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9277 gatgttactg tgactcagtc tccactctcc ctgcccgtca cccttggaca gccggcctcc 60 atctcctgca ggtctagtca aagcctcgta tacagtgatg gaaacaccta cttgaattgg 120 tttcagcaga ggccaggcca atctccaagg cgcctaattt atcaggtttc taaccgggac 180 tctggggtcc cagacagatt cagcggcagt gggtcaggca ctgatttcac actgacaatt 240 agcagggtgg aggctgaaga tgttggggtt tattactgca tgcaaggttc atactggcca 300 ttcactttcg gccctgggac caaagtggat atcaaac 337 <210> 9278 <211> 376 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9278 gaggtgcaat tggtggagtc tgggggaggc ttggtccagc cgggggggtc cctgaggctc 60 tcctgttcag cctctggatt cagttacagt aattattgga tgacttgggt ccgacaggct 120 ccagggaagg ggctggagtg ggtggccaac ctaagacgag atggaagtgt ggagcactat 180 gtggactctg tgaggggccg attcaccatc tccagagaca acgccaagaa ctccctgtat 240 ctacaaatgg acagcctgag agccgaggac acggctgtgt attactgtgc gagagattta 300 agtcccggcg gtttgggggc ctattacgat gtttttgata tctggggcca agggacaatg 360 gtcaccgtct cttcag 376 <210> 9279 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9279 gccatccaga tgacccagtc tccatcctcc ctgtctgcat ctttgggaga cagaatctcc 60 atcacttgcc gggcaagtca gggcattgga aatgagttgg gctggtatca gcagaaacca 120 ggtaaagccc ctagactcct catctatgct ggttccactt tacaaggtgg agtcccacca 180 aggttcagcg gctctggatc tggcacagat ttcactctca ccataagcag cctgcaggct 240 gaagattttg caacatatta ttgtctgcaa gattacgcct accctcggac gttcggccca 300 gggaccaagg tggaagtcaa ac 322 <210> 9280 <211> 375 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9280 gaggtgcagt tgttggagtc ggggggaggc ttggtgcagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt cgtctttagc gactattcca tgaattgggt ccgcctggct 120 ccaggaaagg ggctggcgtg ggtctctgtt gttggtgttg atgccgtcac caaattctat 180 gaagactccg tgaagggccg gttcaccatt tccagagaca actccaagaa cacgatatat 240 ctgcaaatga acaacctgag agccgaagac acggccgtat atcactgtgc gaaaagtcag 300 ccggtgtctc gcatgggtcg cttcttcgtc ggtttggacg tctggggcca agggaccacg 360 gtcaccgtct cctca 375 <210> 9281 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9281 gaaattgtgt tgacgcagtc tccaggcacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttagc agcagctact tagcctggta ccagcagaaa 120 cctggccagg ctcccaggct cctcatctat ggtgcatcca gcagggccac tggcatccca 180 gacaggttca gtggcagtgg gtctgggaca gacttcactc tcaccatcag cagactggag 240 cctgaagatt ttgcagtgta ttactgtcag cagtatggta gctcttacac ttttggccag 300 gggaccaagc tggagatcaa ac 322 <210> 9282 <211> 367 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9282 gaggtgcagc tgttggagtc tgggggaggc ttggtacagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt cacctttagc agctatgcca tgagctgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtctcagct attagtggta gtggtggtag cacatactac 180 gcagactccg tgaagggccg gttcaccatc tccagagaca attccaagaa cacgctgtat 240 ctgcaaatga acagcctgag agccgaggac acggccgtat attactgtgc gaaagatcaa 300 cacatggttc ggggagctat aggctttgac tactggggcc agggaaccct ggtcaccgtc 360 tcctcag 367 <210> 9283 <211> 319 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9283 gaaatagtga tgacgcagtc tccagccacc ctgtctgtgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttagc agcaacttag cctggtacca gcagaaacct 120 ggccaggctc ccaggctcct catctatggt gcatccacca gggccactgg tatcccagcc 180 aggttcagtg gcagtgggtc tgggacagag ttcactctca ccatcagcag cctgcagtct 240 gaagattttg cagtttatta ctgtcagcag tataataact ggcggacgtt cggccaaggg 300 accaaggtgg aaatcaaac 319 <210> 9284 <211> 361 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9284 gaggtgcagt tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt catctttagt aacttttgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atacagcaag atggaagtga gaaatactat 180 gtggactctg tgaagggccg attcaccatc tccacagacc tcgccaagaa ctcactgtat 240 ctgcaaatga acagcctgag agccgaagac acggctgtgt attactgtgc gagacaacac 300 ggtgactacg actggtactt tgactactgg ggccagggaa ccctggtcac cgtctcctca 360 g 361 <210> 9285 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9285 gacatccaga tgacccagtc tccatcttct gtgtctgcat ctgtaggaga cagagtcacc 60 atcacttgtc gggcgagtca gggtattaac agctggttag cctggtatca gcagaaacca 120 gggaaagccc ctaagctcct gatctatgct gcatccagtt tgcaaagtgg ggtcccatca 180 aggttcagcg gcagtggatc tgggacagat ttcactctca ctatcagcag cctgcagcct 240 gaagattttg caacttacta ttgtcaacag gctcacagtt tcccaatcac cttcggccaa 300 gggacacgac tggagattaa ac 322 <210> 9286 <211> 375 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9286 gaggtgcagt tgttggagtc ggggggaggc ttggtgcagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt cgtctttagc gactattcca tgaattgggt ccgcctggct 120 ccaggaaagg ggctggcgtg ggtctctgtt gttggtgttg atgccgtcac caaattctat 180 gaagactccg tgaagggccg gttcaccatt tccagagaca actccaagaa cacgatatat 240 ctgcaaatga acaacctgag agccgaagac acggccgtat atcactgtgc gaaaagtcag 300 ccggtgtctc gcatgggtcg cttcttcgtc ggtttggacg tctggggcca agggaccacg 360 gtcaccgtct cctca 375 <210> 9287 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9287 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9288 <211> 354 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9288 caggtgcaac tggtacaatc cgggggaggc gtggtccagc ctgggaggtc cctgagactc 60 tcctgtacag cctctggatt caccttcagt aattatgcta tgcactgggt ccgccaggcc 120 ccaggcaagg ggctggagtg gggggcagtt atatcatatg acggaactat tacactctat 180 gaagactcca tgaggggccg cttcaccatc tccagagaca attccaggga caccctgtat 240 ctgcaaatga atagtctgcg acctgatgac acggctgtat attactgtgg gagagacctc 300 tctggggggg gtttggacgt ctggggccaa gggaccacgg tcaccgtctc ctca 354 <210> 9289 <211> 329 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9289 cagtctgccc tgactcaggc tcgctcagtg tccgggtctc ctggacagtc agtcaccgtc 60 tcctgcactg gaagcagcaa tgatgttggt ggtcataact atgtctcctg gtaccagcat 120 agcccaggca aagcccccaa actcattatt tatgatgtca ctaaacggcc ctctggggtc 180 cctgatcgct tctccggctc caagtctggc gacacggcct ccctgaccat ctctgggctc 240 caggctgacg atgaaggtga ttattactgc tgctcatata agagtactta cgactatgtc 300 ttcggaagtg ggaccacggt ctccgtcct 329 <210> 9290 <211> 364 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9290 caggtgcagc tggtggagtc tgggggaggc gtggtccagc ctgggaggtc cctgagactc 60 tcctgtgcag cctctggatt caccttcagt atctatgcta tccactgggt ccgccaggct 120 ccaggcaagg ggctggagtg gatggcagtt atatcatatg atggaaataa tcaatactac 180 gcagactccg tgaagggccg attcaccatc tccagagaca attccaagaa cacgctgtat 240 ctgcaaatga acagcctgag aactgacgac acggctgtct attactgtgc gaggagcgag 300 ggagggggtt accatgatgc ttttgatatc tggggccaag ggacaatggt caccgtctct 360 tcag 364 <210> 9291 <211> 334 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9291 cagcttgtgc tgactcaatc gccctctgcc tctgcctccc tgggagcctc ggtcaaactc 60 acctgcactc tgagcagtgg gcacagcagc tacgccatcg cgtggcatca gcagcagcca 120 gagaagggcc ctcggtactt gatgaagctt aacagtgatg gcagccacaa caagggggac 180 gggatccctg atcgcttctc aggctccagc tctggggctg agcgctacct caccatctcc 240 agcctccagt ctgaggatga ggctgactat ttctgtcaga cctggggcac tggcattcac 300 gtgttcggcg gagggaccaa gctgaccgtc ctag 334 <210> 9292 <211> 355 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9292 caggtgcaac tggtggagtc tgggggaggc gtggtccagc ctgggaggtc cctgagactc 60 tcctgtgcag cctctggatt caccttcatt agctatacta tgcactgggt ccgccaggct 120 ccaggcaagg ggctggagtg ggtggcactt atatcatatg atggatacaa taagtactat 180 gcagactccg tgaagggccg atttaccatc tccagagaca attccaagaa cacgctgtat 240 gtgcaaatga acagcctgag agctgaggac acggctctgt attactgtgc gagagaaggg 300 agcccggagg cctttgacta ctggggccag ggaaccctgg tcaccgtctc ctcag 355 <210> 9293 <211> 328 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9293 tcctttgagc tgacacagcc accctcgctg tcagtgtccc caggacagac ggccaggatc 60 acctgctctg gagatgcatt gtcaaagcaa tttacttatt ggtaccagca gaagccaggc 120 caggcccctg tgttggtgat ttataaagac agtgagcggc cctcagggat ccctgagcga 180 ttctctggct ccagctcagg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca cacagcagtg gtttttatcg tgtggtattc 300 ggcggaggga ccaagctgac cgtcctag 328 <210> 9294 <211> 373 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9294 gaggtgcagc tgttggagtc tgggggaggc ttggtacagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt cacctttagc agctatgccg tgtactgggt ccgccaggct 120 ccagggaagg ggctggagtg cgtctcattt attagtggtg gtggtgaaac cacagactac 180 gcagactccg tgaagggccg gttcaccatc tccagagaca attccaagaa cacgttgtat 240 ctgcaaatga acggcctgag agccgaggac acggccgtat attactgtgc gaaatccccg 300 gacgcaacat ttctgtggtt cggggagccc ttcggctact ggggccaggg aaccctggtc 360 accgtctcct cag 373 <210> 9295 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9295 gaaatagtgt tgacgcagtc tccagccacc ctgtctgtgt ctccagggga aagggtcacc 60 ctctcctgca gggccagtca gactgtaaac aacaacttaa actggctcca gcacaaaccg 120 ggccaggctc ccaggctcgt catcattggt acatctacca gggcctctgg tgtcccagcc 180 aggttcagtg gcagtgggtc ggggacagag ttcactctca ccatcagcag cctgcagtct 240 gaggattatg caatttatta ctgtcaacag tattatgagt ggcctccgat cacctacggc 300 caagggacac gactggagat ta 322 <210> 9296 <211> 382 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9296 caggtgcagc tggagcagtc tggggctgag gtgaagaggc ctgggtcttc ggtgaaggtc 60 tcctgcaagg gtgatgggga cacattcagc acatatgcca tcacctgggt gcgacaggcc 120 cctggacaag ggcttgagtg gatggggagg atcatccctg gccttgacct ggtggataat 180 caacagaagt ttcaggacag actgacaatt accgcggaca aatccacgac cacagcctac 240 atggagctga gaagcctcag atctgaagac acggccgtat attattgtgc gagaggtaga 300 cgttacgatt ttttggatgg tcaatatacg tcatggtact tcgacatttg gggccgtggc 360 accctggtca ctgtctcctc ag 382 <210> 9297 <211> 340 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9297 gagatcgtga tgacccagtc tccagactcc ctgactgtgt ctctgggcga gagggccacc 60 atcagctgca agtccagcca gagtctttta tacagttcca acaataggga ctacttagct 120 tggtaccaac agaaagcagg tcagcctcct aagttgctct tttactgggc atctacccgg 180 gaatccgggg tccctgaccg attcggtggc agcgggtctg ggacacattt cactctcacc 240 atctacaacc tgcagcctga agatgtggca gtttatttct gtcagcagta ttttagtcct 300 ccgtatactt ttggccaggg gaccaagctg gagatcaaac 340 <210> 9298 <211> 361 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9298 gaggtgcagt tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60 tcctgtgcag cctctggatt catctttagt aacttttgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atacagcaag atggaagtga gaaatactat 180 gtggactctg tgaagggccg attcaccatc tccacagacc tcgccaagaa ctcactgtat 240 ctgcaaatga acagcctgag agccgaagac acggctgtgt attactgtgc gagacaacac 300 ggtgactacg actggtactt tgactactgg ggccagggaa ccctggtcac cgtctcctca 360 g 361 <210> 9299 <211> 322 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9299 gaaattgtgt tgacgcagtc tccaggcacc ctgtctttgt ctccagggga aagagccacc 60 ctctcctgca gggccagtca gagtgttagc agcagctact tagcctggta ccagcagaaa 120 cctggccagg ctcccaggct cctcatctat ggtgcatcca gcagggccac tggcatccca 180 gacaggttca gtggcagtgg gtctgggaca gacttcactc tcaccatcag cagactggag 240 cctgaagatt ttgcagtgta ttactgtcag cagtatggta gctcttacac ttttggccag 300 gggaccaagc tggagatcaa ac 322 <210> 9300 <211> 352 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9300 gaggtgcagc tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgacactc 60 tcctgtgcag cctctggttt gaccattaga aactattgga tgaactgggt ccgccaggct 120 ccagggaagg ggctggagtg ggtggccaac atggaagaag atggaagtga gaaaaactat 180 gtggactctg tgaagggccg attcatcatc tccagagacg acgccaagaa ctcactatat 240 ctacaaatga acagcctgag agccgaggac acggctgtat attactgtac gagagatccc 300 ggtcccgggg atttttcgtg gggccaggga accgtggtaa ccgtctcctc ag 352 <210> 9301 <211> 325 <212> DNA <213> Artificial sequence <220> <223> Synthetic antibody <400> 9301 tcctatgagc tgacacagcc accctcagtg tcagtgtccc caggacagac ggccaggatc 60 atctgctctg gagatgcatt gccaaagcaa aatgcttatt ggtaccagaa gaagccaggc 120 caggcccctg tgttggtgat atttaaagac agtgagaggc cctcaggcat ccctcagcga 180 ttctctggct ccagctcggg gacaacagtc acgttgacca tcagtggagt ccaggcagaa 240 gacgaggctg actattactg tcaatcagca gacagcagtg gtacttatgt ggtattcggc 300 ggagggacca agctgaccgt cctag 325 <210> 9302 <211> 118 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9302 Gln Val Gln Leu Val Gln Ser Gly Ser Glu Leu Gln Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Asn Thr Phe Pro Thr Tyr 20 25 30 Asp Met Asn Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Met 35 40 45 Gly Trp Ile Asn Thr Asn Thr Gly Ser Pro Thr Tyr Ala Gln Gly Leu 50 55 60 Pro Gly Arg Phe Val Phe Ser Leu Asp Thr Ser Val Ser Thr Ala Tyr 65 70 75 80 Leu Glu Ile Ser Ser Leu Lys Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Glu Gly Tyr His Tyr Gly Met Asp Val Trp Gly Gln Gly Thr 100 105 110 Thr Val Thr Val Ser Ser 115 <210> 9303 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9303 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Asp Ile Asn Asn Tyr 20 25 30 Leu Ala Trp Phe Gln Gln Lys Pro Gly Lys Ala Pro Lys Ser Leu Ile 35 40 45 Tyr Ser Ala Ser Ser Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Phe Ala Thr Tyr Tyr Cys Gln Gln Tyr Arg Ser Tyr Pro Arg 85 90 95 Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 <210> 9304 <211> 119 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9304 Gln Ala His Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Gly Thr Phe Asn Ser His 20 25 30 Ala Ile Gly Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Met 35 40 45 Gly Arg Ile Val Pro Ile Arg Lys Thr Thr Thr Tyr Ala Pro Gln Leu 50 55 60 Gln Gly Arg Leu Thr Leu Thr Ala Asp Thr Ser Thr Ser Thr Leu Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Ser Ala Arg Tyr Tyr Cys 85 90 95 Ala Arg Val Ile Leu Ser Gly Arg Gly Phe Asp Ile Trp Gly Gln Gly 100 105 110 Ser Leu Val Ala Val Ser Ser 115 <210> 9305 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9305 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9306 <211> 120 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9306 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Ile Phe Ser Asn Phe 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Ile Gln Gln Asp Gly Ser Glu Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Thr Asp Leu Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9307 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9307 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9308 <211> 120 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9308 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Ile Phe Ser Asn Phe 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Ile Gln Gln Asp Gly Ser Glu Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Thr Asp Leu Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9309 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9309 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Asp Ile Asn Asn Tyr 20 25 30 Leu Ala Trp Phe Gln Gln Lys Pro Gly Lys Ala Pro Lys Ser Leu Ile 35 40 45 Tyr Ser Ala Ser Ser Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Phe Ala Thr Tyr Tyr Cys Gln Gln Tyr Arg Ser Tyr Pro Arg 85 90 95 Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 <210> 9310 <211> 124 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9310 Glu Val Gln Leu Leu Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Ala Val Tyr Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Cys Val 35 40 45 Ser Phe Ile Ser Gly Gly Gly Glu Thr Thr Asp Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 65 70 75 80 Leu Gln Met Asn Gly Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Lys Ser Pro Asp Ala Thr Phe Leu Trp Phe Gly Glu Pro Phe Gly 100 105 110 Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9311 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9311 Glu Ile Val Leu Thr Gln Ser Pro Gly Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Glu Ser Val Ser Ser Asn 20 25 30 Tyr Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu 35 40 45 Ile Tyr Asp Ala Ser Ser Arg Ala Thr Gly Ile Pro Asp Arg Phe Ser 50 55 60 Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Lys Leu Glu 65 70 75 80 Pro Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Ala Arg Ala Pro 85 90 95 Asp Thr Phe Ala Gln Gly Thr Arg Leu Glu Ile Lys 100 105 <210> 9312 <211> 121 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9312 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Ala Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Val Ile Ser Tyr Asp Gly Ser Asn Lys Tyr Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Asp Pro Asn Pro Met Val Leu Ala Tyr Phe Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9313 <211> 110 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9313 Gln Thr Val Val Thr Gln Glu Pro Ser Phe Ser Val Ser Pro Gly Gly 1 5 10 15 Thr Val Thr Leu Thr Cys Gly Leu Ser Ser Gly Ser Val Ser Thr Ser 20 25 30 Tyr Tyr Pro Ser Trp Tyr Gln Gln Thr Pro Gly Gln Ala Pro Arg Thr 35 40 45 Leu Ile Tyr Ser Thr Asn Thr Arg Ser Ser Gly Val Pro Asp Arg Phe 50 55 60 Ser Gly Ser Ile Leu Gly Asn Lys Ala Ala Leu Thr Ile Thr Gly Ala 65 70 75 80 Gln Ala Asp Asp Glu Ser Asp Tyr Tyr Cys Val Leu Tyr Met Gly Ser 85 90 95 Gly Ile Trp Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 110 <210> 9314 <211> 124 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9314 Glu Val Gln Leu Leu Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Ala Val Tyr Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Cys Val 35 40 45 Ser Phe Ile Ser Gly Gly Gly Glu Thr Thr Asp Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 65 70 75 80 Leu Gln Met Asn Gly Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Lys Ser Pro Asp Ala Thr Phe Leu Trp Phe Gly Glu Pro Phe Gly 100 105 110 Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9315 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9315 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9316 <211> 120 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9316 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Asn Leu Ser Asn Tyr 20 25 30 Ala Met His Trp Val Arg Gln Ala Ser Gly Lys Gly Leu Glu Trp Val 35 40 45 Ser Leu Ile Ser Tyr Asp Gly Ser Ile Lys Tyr Tyr Thr Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Val Ser Gly Asp Asn Ser Lys Asn Thr Leu Phe 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Pro Asp Asp Ser Ala Leu Tyr Tyr Cys 85 90 95 Val Arg Gly Gly Val Ser Gly Pro Asn Ser Phe Asp Met Trp Gly Gln 100 105 110 Gly Thr Thr Val Thr Val Ser Ser 115 120 <210> 9317 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9317 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9318 <211> 117 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9318 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Thr Leu Ser Cys Ala Ala Ser Gly Leu Thr Ile Arg Asn Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Met Glu Glu Asp Gly Ser Glu Lys Asn Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Ile Ile Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser Trp Gly Gln Gly Thr Val 100 105 110 Val Thr Val Ser Ser 115 <210> 9319 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9319 Glu Ile Val Leu Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Val Thr Leu Ser Cys Arg Ala Ser Gln Thr Val Asn Asn Asn 20 25 30 Leu Asn Trp Leu Gln His Lys Pro Gly Gln Ala Pro Arg Leu Val Ile 35 40 45 Ile Gly Thr Ser Thr Arg Ala Ser Gly Val Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Glu Phe Thr Leu Thr Ile Ser Ser Leu Gln Ser 65 70 75 80 Glu Asp Tyr Ala Ile Tyr Tyr Cys Gln Gln Tyr Tyr Glu Trp Pro Pro 85 90 95 Ile Thr Tyr Gly Gln Gly Thr Arg Leu Glu Ile 100 105 <210> 9320 <211> 124 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9320 Gln Val Gln Leu Gln Gln Ser Gly Pro Gly Leu Val Arg Pro Ser Gly 1 5 10 15 Thr Leu Ser Leu Thr Cys Gly Val Ser Gly Gly Ser Ile Ser Ser Pro 20 25 30 Asn Trp Trp Ser Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp 35 40 45 Ile Gly Glu Val Tyr Pro Thr Gly Asn Thr Tyr Tyr Asn Pro Ser Leu 50 55 60 Lys Ser Arg Val Thr Ile Ser Ile Glu Glu Ser Lys Asn Glu Phe Ser 65 70 75 80 Leu Asn Leu Ser Ser Val Thr Ala Ala Asp Met Gly Ile Tyr Tyr Cys 85 90 95 Ala Arg Gly Val Val Gly Ala Ser Asp Phe Tyr Tyr Tyr Gly Met Asp 100 105 110 Val Trp Gly Gln Gly Thr Ala Val Thr Val Ser Ser 115 120 <210> 9321 <211> 113 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9321 Glu Ile Val Met Thr Gln Ser Pro Asp Ser Leu Thr Val Ser Leu Gly 1 5 10 15 Glu Arg Ala Thr Ile Ser Cys Lys Ser Ser Gln Ser Leu Leu Tyr Ser 20 25 30 Ser Asn Asn Arg Asp Tyr Leu Ala Trp Tyr Gln Gln Lys Ala Gly Gln 35 40 45 Pro Pro Lys Leu Leu Phe Tyr Trp Ala Ser Thr Arg Glu Ser Gly Val 50 55 60 Pro Asp Arg Phe Gly Gly Ser Gly Ser Gly Thr His Phe Thr Leu Thr 65 70 75 80 Ile Tyr Asn Leu Gln Pro Glu Asp Val Ala Val Tyr Phe Cys Gln Gln 85 90 95 Tyr Phe Ser Pro Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile 100 105 110 Lys <210> 9322 <211> 121 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9322 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Gln 1 5 10 15 Thr Leu Ser Leu Asn Cys Ser Val Ser Gly Asp Ser Ile Ser Arg Ser 20 25 30 Asp Tyr His Trp Ser Trp Ile Arg Gln His Pro Gly Lys Gly Leu Glu 35 40 45 Trp Ile Gly Tyr Ile Tyr Asn Asn Gly Asp Thr Tyr Tyr Asn Pro Ser 50 55 60 Leu Lys Ser Arg Val Thr Met Ser Val Asp Thr Ser Lys Asn Glu Phe 65 70 75 80 Ser Leu Lys Leu Thr Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr 85 90 95 Cys Ala Arg Asp Gly Tyr Ala Gly Asn Ser Glu Ala Leu Asp Tyr Trp 100 105 110 Gly Gln Gly Thr Leu Val Thr Val Ser 115 120 <210> 9323 <211> 109 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9323 Glu Ile Val Leu Thr Gln Ser Pro Ala Ser Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Thr Asn Tyr 20 25 30 Leu Ala Trp Tyr Gln Gln Arg Pro Gly Gln Ala Pro Arg Leu Leu Ile 35 40 45 Tyr Gln Thr Ser Asn Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Glu Pro 65 70 75 80 Glu Asp Phe Ala Phe Tyr Tyr Cys Gln Gln Arg Ser His Arg Pro Gly 85 90 95 Gly Ile Thr Phe Gly Gln Gly Thr Arg Leu Glu Ile Lys 100 105 <210> 9324 <211> 120 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9324 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Ile Phe Ser Asn Phe 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Ile Gln Gln Asp Gly Ser Glu Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Thr Asp Leu Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9325 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9325 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Gln Ala Ser Gln Asp Ile Ser Asn Tyr 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Asp Asn Leu Pro Leu 85 90 95 Thr Phe Gly Pro Gly Thr Lys Val Asp Ile Lys 100 105 <210> 9326 <211> 120 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9326 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Ile Phe Ser Asn Phe 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Ile Gln Gln Asp Gly Ser Glu Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Thr Asp Leu Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9327 <211> 113 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9327 Glu Ile Val Met Thr Gln Ser Pro Asp Ser Leu Thr Val Ser Leu Gly 1 5 10 15 Glu Arg Ala Thr Ile Ser Cys Lys Ser Ser Gln Ser Leu Leu Tyr Ser 20 25 30 Ser Asn Asn Arg Asp Tyr Leu Ala Trp Tyr Gln Gln Lys Ala Gly Gln 35 40 45 Pro Pro Lys Leu Leu Phe Tyr Trp Ala Ser Thr Arg Glu Ser Gly Val 50 55 60 Pro Asp Arg Phe Gly Gly Ser Gly Ser Gly Thr His Phe Thr Leu Thr 65 70 75 80 Ile Tyr Asn Leu Gln Pro Glu Asp Val Ala Val Tyr Phe Cys Gln Gln 85 90 95 Tyr Phe Ser Pro Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile 100 105 110 Lys <210> 9328 <211> 122 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9328 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Lys Pro Gly Glu 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Lys Phe Thr Phe Ser Thr Tyr 20 25 30 His Met Asn Trp Ile Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ser Ala Ile Ser Ala Asp Ser Thr Val Thr Thr Tyr Ala Asp Ser Val 50 55 60 Arg Gly Arg Phe Ile Ile Ser Arg Asp Asn Asp Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Gly Leu Arg Val Asp Asp Leu Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gly Arg Ala Arg Gly Ser Asp His Thr Gly Phe Asp Ser Trp 100 105 110 Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9329 <211> 113 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9329 Asp Ile Val Met Thr Gln Ser Pro Leu Ser Leu Ser Val Thr Pro Gly 1 5 10 15 Glu Pro Ala Ser Ile Ser Cys Arg Ser Ser Gln Ser Leu Leu His Arg 20 25 30 Asn Gly Tyr Asn Ile Leu Asp Trp Tyr Leu Gln Lys Pro Gly Gln Ser 35 40 45 Pro Gln Leu Leu Ile Tyr Leu Gly Ser Asn Arg Ala Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln Gly 85 90 95 Leu Gln Thr Pro Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile 100 105 110 Lys <210> 9330 <211> 120 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9330 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Ile Phe Ser Asn Phe 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Ile Gln Gln Asp Gly Ser Glu Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Thr Asp Leu Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9331 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9331 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Ser Ile Thr Thr Tyr 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Ala Gly Lys Ala Pro Asn Leu Leu Ile 35 40 45 Tyr Ala Pro Ser Asn Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Phe Gly Thr Tyr Tyr Cys Gln Gln Ser Tyr Ser Ser Pro Phe 85 90 95 Thr Phe Gly Pro Gly Thr Lys Val Asp Ile Lys 100 105 <210> 9332 <211> 120 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9332 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Ile Phe Ser Asn Phe 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Ile Gln Gln Asp Gly Ser Glu Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Thr Asp Leu Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9333 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9333 Glu Ile Val Leu Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Val Thr Leu Ser Cys Arg Ala Ser Gln Thr Val Asn Asn Asn 20 25 30 Leu Asn Trp Leu Gln His Lys Pro Gly Gln Ala Pro Arg Leu Val Ile 35 40 45 Ile Gly Thr Ser Thr Arg Ala Ser Gly Val Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Glu Phe Thr Leu Thr Ile Ser Ser Leu Gln Ser 65 70 75 80 Glu Asp Tyr Ala Ile Tyr Tyr Cys Gln Gln Tyr Tyr Glu Trp Pro Pro 85 90 95 Ile Thr Tyr Gly Gln Gly Thr Arg Leu Glu Ile 100 105 <210> 9334 <211> 124 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9334 Gln Val Gln Leu Gln Gln Ser Gly Pro Gly Leu Val Arg Pro Ser Gly 1 5 10 15 Thr Leu Ser Leu Thr Cys Gly Val Ser Gly Gly Ser Ile Ser Ser Pro 20 25 30 Asn Trp Trp Ser Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp 35 40 45 Ile Gly Glu Val Tyr Pro Thr Gly Asn Thr Tyr Tyr Asn Pro Ser Leu 50 55 60 Lys Ser Arg Val Thr Ile Ser Ile Glu Glu Ser Lys Asn Glu Phe Ser 65 70 75 80 Leu Asn Leu Ser Ser Val Thr Ala Ala Asp Met Gly Ile Tyr Tyr Cys 85 90 95 Ala Arg Gly Val Val Gly Ala Ser Asp Phe Tyr Tyr Tyr Gly Met Asp 100 105 110 Val Trp Gly Gln Gly Thr Ala Val Thr Val Ser Ser 115 120 <210> 9335 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9335 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9336 <211> 112 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9336 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr 20 25 30 Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Tyr Ile 35 40 45 Gly Tyr Ile Tyr Tyr Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys 50 55 60 Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Leu Ser Leu 65 70 75 80 Lys Leu Arg Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 85 90 95 Arg Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 100 105 110 <210> 9337 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9337 Glu Ile Val Leu Thr Gln Ser Pro Gly Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Ser 20 25 30 Tyr Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu 35 40 45 Ile Tyr Gly Thr Ser Ser Arg Ala Thr Gly Ile Pro Asp Arg Phe Ser 50 55 60 Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Arg Leu Glu 65 70 75 80 Pro Glu Asp Phe Ala Val Phe Tyr Cys Gln Gln Tyr Gly Asn Ser Pro 85 90 95 Trp Thr Phe Gly Gln Gly Thr Lys Val Glu Ile Lys 100 105 <210> 9338 <211> 117 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9338 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Thr Leu Ser Cys Ala Ala Ser Gly Leu Thr Ile Arg Asn Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Met Glu Glu Asp Gly Ser Glu Lys Asn Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Ile Ile Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser Trp Gly Gln Gly Thr Val 100 105 110 Val Thr Val Ser Ser 115 <210> 9339 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9339 Glu Ile Val Leu Thr Gln Ser Pro Ala Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Tyr 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu Ile 35 40 45 Phe Asp Ala Ser Asn Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Glu Pro 65 70 75 80 Glu Asp Phe Ala Val Tyr Phe Cys Gln Gln Arg Ser Ser Trp Gln Gly 85 90 95 Ile Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys 100 105 <210> 9340 <211> 120 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9340 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Ile Phe Ser Asn Phe 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Ile Gln Gln Asp Gly Ser Glu Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Thr Asp Leu Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9341 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9341 Glu Ile Val Leu Thr Gln Ser Pro Ala Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Tyr 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu Ile 35 40 45 Phe Asp Ala Ser Asn Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Glu Pro 65 70 75 80 Glu Asp Phe Ala Val Tyr Phe Cys Gln Gln Arg Ser Ser Trp Gln Gly 85 90 95 Ile Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys 100 105 <210> 9342 <211> 124 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9342 Gln Val Gln Leu Gln Gln Ser Gly Pro Gly Leu Val Arg Pro Ser Gly 1 5 10 15 Thr Leu Ser Leu Thr Cys Gly Val Ser Gly Gly Ser Ile Ser Ser Pro 20 25 30 Asn Trp Trp Ser Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp 35 40 45 Ile Gly Glu Val Tyr Pro Thr Gly Asn Thr Tyr Tyr Asn Pro Ser Leu 50 55 60 Lys Ser Arg Val Thr Ile Ser Ile Glu Glu Ser Lys Asn Glu Phe Ser 65 70 75 80 Leu Asn Leu Ser Ser Val Thr Ala Ala Asp Met Gly Ile Tyr Tyr Cys 85 90 95 Ala Arg Gly Val Val Gly Ala Ser Asp Phe Tyr Tyr Tyr Gly Met Asp 100 105 110 Val Trp Gly Gln Gly Thr Ala Val Thr Val Ser Ser 115 120 <210> 9343 <211> 106 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9343 Glu Ile Val Leu Thr Gln Ser Pro Ala Thr Pro Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Tyr 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu Ile 35 40 45 Phe Asp Ala Ser Asn Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Glu Ser 65 70 75 80 Glu Asp Phe Gly Thr Tyr Tyr Cys Gln Gln Tyr Asn His Trp Arg Thr 85 90 95 Phe Gly Gln Gly Thr Lys Val Glu Ile Lys 100 105 <210> 9344 <211> 117 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9344 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Thr Leu Ser Cys Ala Ala Ser Gly Leu Thr Ile Arg Asn Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Met Glu Glu Asp Gly Ser Glu Lys Asn Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Ile Ile Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser Trp Gly Gln Gly Thr Val 100 105 110 Val Thr Val Ser Ser 115 <210> 9345 <211> 113 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9345 Glu Ile Val Met Thr Gln Ser Pro Asp Ser Leu Thr Val Ser Leu Gly 1 5 10 15 Glu Arg Ala Thr Ile Ser Cys Lys Ser Ser Gln Ser Leu Leu Tyr Ser 20 25 30 Ser Asn Asn Arg Asp Tyr Leu Ala Trp Tyr Gln Gln Lys Ala Gly Gln 35 40 45 Pro Pro Lys Leu Leu Phe Tyr Trp Ala Ser Thr Arg Glu Ser Gly Val 50 55 60 Pro Asp Arg Phe Gly Gly Ser Gly Ser Gly Thr His Phe Thr Leu Thr 65 70 75 80 Ile Tyr Asn Leu Gln Pro Glu Asp Val Ala Val Tyr Phe Cys Gln Gln 85 90 95 Tyr Phe Ser Pro Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile 100 105 110 Lys <210> 9346 <211> 120 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9346 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Ile Phe Ser Asn Phe 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Ile Gln Gln Asp Gly Ser Glu Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Thr Asp Leu Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9347 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9347 Glu Ile Val Leu Thr Gln Ser Pro Gly Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Glu Ser Val Ser Ser Asn 20 25 30 Tyr Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu 35 40 45 Ile Tyr Asp Ala Ser Ser Arg Ala Thr Gly Ile Pro Asp Arg Phe Ser 50 55 60 Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Lys Leu Glu 65 70 75 80 Pro Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Ala Arg Ala Pro 85 90 95 Asp Thr Phe Ala Gln Gly Thr Arg Leu Glu Ile Lys 100 105 <210> 9348 <211> 127 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9348 Gln Met Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Gly Thr Phe Ile Asn Tyr 20 25 30 Ala Ile Asn Trp Val Arg Gln Ala Pro Gly Gln Arg Leu Glu Tyr Met 35 40 45 Gly Gly Ile Ile Pro Leu Leu Gly Val Ala Asn Tyr Thr Gln Arg Phe 50 55 60 Gln Gly Arg Val Thr Met Thr Ala Asp Arg Ser Thr Ser Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Asn Leu Ala Ile Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Glu Tyr Ser Ser Ser Arg Pro Leu Phe Tyr Thr Tyr Asn Tyr 100 105 110 Gly Met Asp Val Trp Gly Gln Gly Thr Thr Val Thr Val Ser Ser 115 120 125 <210> 9349 <211> 112 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9349 Asp Ile Val Met Thr Gln Thr Pro Leu Ser Leu Ser Val Thr Pro Gly 1 5 10 15 Gln Pro Ala Ser Ile Ser Cys Lys Ser Ser Gln Gly Leu Leu His Gly 20 25 30 Asp Gly Lys Thr Tyr Leu Tyr Trp Phe Leu Gln Lys Ala Gly Gln Pro 35 40 45 Pro Gln Leu Leu Ile Tyr Glu Val Ser Asn Arg Phe Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Ile Tyr Tyr Cys Met Gln Ser 85 90 95 Val His Leu Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 110 <210> 9350 <211> 117 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9350 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Thr Leu Ser Cys Ala Ala Ser Gly Leu Thr Ile Arg Asn Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Met Glu Glu Asp Gly Ser Glu Lys Asn Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Ile Ile Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser Trp Gly Gln Gly Thr Val 100 105 110 Val Thr Val Ser Ser 115 <210> 9351 <211> 106 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9351 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Ser Ile Thr Cys Ser Gly Asp Lys Leu Gly Glu Lys Tyr Ala 20 25 30 Cys Trp Tyr Gln Gln Lys Pro Gly Gln Ser Pro Val Leu Val Ile Tyr 35 40 45 Gln Asp Thr Lys Arg Pro Ser Gly Ile Pro Glu Arg Phe Ser Gly Ser 50 55 60 Asn Ser Gly Asn Thr Ala Thr Leu Thr Ile Ser Gly Thr Gln Ala Val 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ala Trp Asp Tyr Thr Thr Val Ile 85 90 95 Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9352 <211> 117 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9352 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Thr Leu Ser Cys Ala Ala Ser Gly Leu Thr Ile Arg Asn Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Met Glu Glu Asp Gly Ser Glu Lys Asn Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Ile Ile Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser Trp Gly Gln Gly Thr Val 100 105 110 Val Thr Val Ser Ser 115 <210> 9353 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9353 Glu Ile Val Leu Thr Gln Ser Pro Gly Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Ser 20 25 30 Tyr Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu 35 40 45 Ile Tyr Gly Ala Ser Ser Arg Ala Thr Gly Ile Pro Asp Arg Phe Ser 50 55 60 Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Arg Leu Glu 65 70 75 80 Pro Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Gly Ser Ser Tyr 85 90 95 Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 <210> 9354 <211> 117 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9354 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Thr Leu Ser Cys Ala Ala Ser Gly Leu Thr Ile Arg Asn Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Met Glu Glu Asp Gly Ser Glu Lys Asn Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Ile Ile Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser Trp Gly Gln Gly Thr Val 100 105 110 Val Thr Val Ser Ser 115 <210> 9355 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9355 Glu Ile Val Leu Thr Gln Ser Pro Ala Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Tyr 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu Ile 35 40 45 Phe Asp Ala Ser Asn Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Phe Ala Thr Tyr Tyr Cys Gln Gln Tyr Arg Ser Tyr Pro Arg 85 90 95 Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 <210> 9356 <211> 117 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9356 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Thr Leu Ser Cys Ala Ala Ser Gly Leu Thr Ile Arg Asn Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Met Glu Glu Asp Gly Ser Glu Lys Asn Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Ile Ile Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser Trp Gly Gln Gly Thr Val 100 105 110 Val Thr Val Ser Ser 115 <210> 9357 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9357 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Ser Ile Thr Thr Tyr 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Ala Gly Lys Ala Pro Asn Leu Leu Ile 35 40 45 Tyr Ala Pro Ser Asn Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Phe Gly Thr Tyr Tyr Cys Gln Gln Ser Tyr Ser Ser Pro Phe 85 90 95 Thr Phe Gly Pro Gly Thr Lys Val Asp Ile Lys 100 105 <210> 9358 <211> 127 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9358 Gln Val Gln Leu Glu Gln Ser Gly Ala Glu Val Lys Arg Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Gly Asp Gly Asp Thr Phe Ser Thr Tyr 20 25 30 Ala Ile Thr Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Met 35 40 45 Gly Arg Ile Ile Pro Gly Leu Asp Leu Val Asp Asn Gln Gln Lys Phe 50 55 60 Gln Asp Arg Leu Thr Ile Thr Ala Asp Lys Ser Thr Thr Thr Ala Tyr 65 70 75 80 Met Glu Leu Arg Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gly Arg Arg Tyr Asp Phe Leu Asp Gly Gln Tyr Thr Ser Trp 100 105 110 Tyr Phe Asp Ile Trp Gly Arg Gly Thr Leu Val Thr Val Ser Ser 115 120 125 <210> 9359 <211> 112 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9359 Asn Ile Val Met Thr Gln Ser Pro Leu Ser Leu Pro Val Thr Pro Gly 1 5 10 15 Glu Pro Ala Ser Met Ser Cys Arg Ser Asn Gln Ser Leu Leu Tyr Gly 20 25 30 Asn Gly Tyr Asn Tyr Leu Asp Trp Tyr Leu Gln Arg Pro Gly Gln Ser 35 40 45 Pro Gln Leu Leu Ile Phe Leu Gly Ser Asn Arg Ala Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Asn Arg Val Glu Ala Glu Asp Val Gly Ile Tyr Tyr Cys Met Gln Gly 85 90 95 Gln Glu Asn Pro Pro Thr Phe Gly Pro Gly Thr Lys Val Glu Ile Lys 100 105 110 <210> 9360 <211> 124 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9360 Glu Val Gln Leu Leu Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Ala Val Tyr Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Cys Val 35 40 45 Ser Phe Ile Ser Gly Gly Gly Glu Thr Thr Asp Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 65 70 75 80 Leu Gln Met Asn Gly Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Lys Ser Pro Asp Ala Thr Phe Leu Trp Phe Gly Glu Pro Phe Gly 100 105 110 Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9361 <211> 106 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9361 Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Asn 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu Ile 35 40 45 Tyr Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Ser 65 70 75 80 Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Asn Asn Trp Arg Thr 85 90 95 Phe Gly Gln Gly Thr Lys Val Glu Ile Lys 100 105 <210> 9362 <211> 118 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9362 Gln Met Gln Leu Val Gln Ser Gly Thr Glu Val Lys Lys Pro Gly Glu 1 5 10 15 Ser Leu Lys Ile Ser Cys Lys Gly Ser Gly Tyr Gly Phe Ile Thr Tyr 20 25 30 Trp Ile Gly Trp Val Arg Gln Met Pro Gly Lys Gly Leu Glu Trp Met 35 40 45 Gly Ile Ile Tyr Pro Gly Asp Ser Glu Thr Arg Tyr Ser Pro Ser Phe 50 55 60 Gln Gly Gln Val Thr Ile Ser Ala Asp Lys Ser Ile Asn Thr Ala Tyr 65 70 75 80 Leu Gln Trp Ser Ser Leu Lys Ala Ser Asp Thr Ala Ile Tyr Tyr Cys 85 90 95 Ala Gly Gly Ser Gly Ile Ser Thr Pro Met Asp Val Trp Gly Gln Gly 100 105 110 Thr Thr Val Thr Val Ser 115 <210> 9363 <211> 86 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9363 Ser Val Leu Tyr Ser Ser Ile Asn Lys Asn Tyr Leu Ala Trp Tyr Gln 1 5 10 15 Gln Lys Pro Gly Gln Pro Pro Lys Leu Leu Ile Tyr Trp Ala Ser Thr 20 25 30 Arg Glu Ser Gly Val Pro Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr 35 40 45 Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Ala Glu Asp Val Ala Val 50 55 60 Tyr Tyr Cys Gln Gln Tyr Tyr Ser Thr Pro Tyr Thr Phe Gly Gln Gly 65 70 75 80 Thr Lys Val Glu Ile Lys 85 <210> 9364 <211> 125 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9364 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Gln 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Gly 20 25 30 Ser His Tyr Trp Ser Trp Ile Arg Gln Pro Ala Gly Lys Gly Leu Glu 35 40 45 Trp Val Gly Arg Ile Tyr Thr Ser Gly Ser Thr Asn Tyr Asn Pro Ser 50 55 60 Leu Glu Arg Arg Val Thr Ile Ser Leu Gly Thr Ser Lys Asn Gln Phe 65 70 75 80 Tyr Leu Asp Leu Thr Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr 85 90 95 Cys Ala Arg Asp Ser Leu Ser Gly Ser Tyr His Tyr Tyr Tyr Gly Met 100 105 110 Asp Val Trp Gly Gln Gly Thr Ser Val Thr Val Ser Ser 115 120 125 <210> 9365 <211> 110 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9365 Gln Ser Val Leu Thr Gln Pro Pro Ser Ala Ser Gly Thr Pro Gly Gln 1 5 10 15 Arg Val Thr Ile Ser Cys Ser Gly Ser Ser Ser Asn Ile Gly Ser Asn 20 25 30 Tyr Val Tyr Trp Tyr Gln His Leu Pro Gly Thr Ala Pro Lys Leu Leu 35 40 45 Ile Tyr Arg Asn Tyr Gln Arg Pro Ser Gly Val Pro Asp Arg Phe Ser 50 55 60 Gly Ser Lys Ser Gly Thr Ser Ala Ser Leu Ala Ile Ser Gly Leu Arg 65 70 75 80 Ser Glu Asp Glu Gly Asp Tyr Tyr Cys Ala Val Trp Asp Asp Ser Leu 85 90 95 Ser Gly Trp Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 110 <210> 9366 <211> 118 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9366 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ile Ser Tyr 20 25 30 Thr Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Leu Ile Ser Tyr Asp Gly Tyr Asn Lys Tyr Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 65 70 75 80 Val Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys 85 90 95 Ala Arg Glu Gly Ser Pro Glu Ala Phe Asp Tyr Trp Gly Gln Gly Thr 100 105 110 Leu Val Thr Val Ser Ser 115 <210> 9367 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9367 Glu Ile Val Leu Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Val Thr Leu Ser Cys Arg Ala Ser Gln Thr Val Asn Asn Asn 20 25 30 Leu Asn Trp Leu Gln His Lys Pro Gly Gln Ala Pro Arg Leu Val Ile 35 40 45 Ile Gly Thr Ser Thr Arg Ala Ser Gly Val Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Glu Phe Thr Leu Thr Ile Ser Ser Leu Gln Ser 65 70 75 80 Glu Asp Tyr Ala Ile Tyr Tyr Cys Gln Gln Tyr Tyr Glu Trp Pro Pro 85 90 95 Ile Thr Tyr Gly Gln Gly Thr Arg Leu Glu Ile 100 105 <210> 9368 <211> 124 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9368 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Arg Arg Leu Ser Cys Gly Ala Ser Gly Phe Thr Phe Thr Asn His 20 25 30 Trp Met Ser Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Ser Ile Lys Gln Asp Gly Ala Glu Lys Tyr Tyr Val Asp Tyr Leu 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Val Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Arg Ile Thr Met Ala Leu Ala Gly Trp Gly Trp Gly Met Asp 100 105 110 Val Trp Gly Gln Gly Thr Thr Val Arg Val Ser Ser 115 120 <210> 9369 <211> 112 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9369 Asp Ile Val Met Thr Gln Ser Pro Leu Ser Leu Pro Val Thr Pro Gly 1 5 10 15 Glu Pro Ala Ser Ile Ser Cys Arg Ser Ser Arg Ser Leu Leu Ser Arg 20 25 30 Asn Gly Tyr Asn Tyr Leu Asp Trp Tyr Leu Gln Arg Pro Gly Gln Ser 35 40 45 Pro Gln Leu Val Ile Tyr Leu Gly Ser Asn Arg Ala Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Leu Tyr Tyr Cys Met Gln Ala 85 90 95 Met Gln Ala Pro Leu Thr Phe Gly Pro Gly Thr Lys Val Glu Ile Lys 100 105 110 <210> 9370 <211> 126 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9370 Gln Val Gln Leu Val Gln Ser Gly Ser Glu Leu Lys Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Val Ser Cys Lys Thr Ser Gly Tyr Thr Phe Thr Ser Tyr 20 25 30 Ala Ile Asn Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Trp Ile Asn Ile Asn Thr Gly Asn Pro Thr Tyr Ala Gln Gly Phe 50 55 60 Thr Gly Arg Val Asp Phe Ser Leu Asp Thr Ser Val Ser Thr Ala Tyr 65 70 75 80 Leu Gln Ile Arg Ser Leu Lys Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Asp Arg Gly Ile Ala Ala Arg Arg Gly Tyr Tyr Tyr Tyr Gly 100 105 110 Met Asp Val Trp Gly Gln Gly Thr Thr Val Thr Val Ser Ser 115 120 125 <210> 9371 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9371 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9372 <211> 127 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9372 Gln Val Gln Leu Glu Gln Ser Gly Ala Glu Val Lys Arg Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Gly Asp Gly Asp Thr Phe Ser Thr Tyr 20 25 30 Ala Ile Thr Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Met 35 40 45 Gly Arg Ile Ile Pro Gly Leu Asp Leu Val Asp Asn Gln Gln Lys Phe 50 55 60 Gln Asp Arg Leu Thr Ile Thr Ala Asp Lys Ser Thr Thr Thr Ala Tyr 65 70 75 80 Met Glu Leu Arg Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gly Arg Arg Tyr Asp Phe Leu Asp Gly Gln Tyr Thr Ser Trp 100 105 110 Tyr Phe Asp Ile Trp Gly Arg Gly Thr Leu Val Thr Val Ser Ser 115 120 125 <210> 9373 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9373 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9374 <211> 112 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9374 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr 20 25 30 Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Tyr Ile 35 40 45 Gly Tyr Ile Tyr Tyr Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys 50 55 60 Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Leu Ser Leu 65 70 75 80 Lys Leu Arg Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 85 90 95 Arg Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 100 105 110 <210> 9375 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9375 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9376 <211> 121 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9376 Gln Val Gln Leu Gln Gln Trp Gly Ala Gly Leu Leu Lys Pro Ser Glu 1 5 10 15 Thr Leu Ser Leu Thr Cys Ala Val His Gly Gly Ser Phe Ser Gly Pro 20 25 30 Tyr Trp Thr Trp Ile Arg Gln Ser Pro Ser Gln Gly Leu Glu Trp Ile 35 40 45 Gly Glu Ile Gly Pro Arg Gly Ile Thr Tyr Tyr Ser Pro Ser Leu Glu 50 55 60 Ser Arg Val Thr Ile Ser Ala Asp Thr Ser Arg Asn Gln Phe Ser Leu 65 70 75 80 Arg Leu Thr Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 85 90 95 Arg Gly Leu Val Ile Gly Arg Ser Ser Leu Asn Phe Asp Ser Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9377 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9377 Glu Ile Val Leu Thr Gln Ser Pro Gly Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Glu Ser Val Ser Ser Asn 20 25 30 Tyr Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu 35 40 45 Ile Tyr Asp Ala Ser Ser Arg Ala Thr Gly Ile Pro Asp Arg Phe Ser 50 55 60 Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Lys Leu Glu 65 70 75 80 Pro Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Ala Arg Ala Pro 85 90 95 Asp Thr Phe Ala Gln Gly Thr Arg Leu Glu Ile Lys 100 105 <210> 9378 <211> 119 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9378 Glu Val Gln Leu Val Glu Ala Gly Gly Gly Leu Val Lys Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Gly Tyr 20 25 30 Ala Ile Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ser Ser Ile Ser Gly Asn Asn Asn Asp Met Tyr Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Ser Ser Val Phe 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Val Glu Asp Thr Ala Ile Tyr Tyr Cys 85 90 95 Ala Arg Asp Asn Leu Ala Leu Ala Gly Glu Asp Tyr Trp Gly Gln Gly 100 105 110 Thr Leu Val Thr Val Ser Ser 115 <210> 9379 <211> 113 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9379 Glu Ile Val Met Thr Gln Ser Pro Asp Ser Leu Thr Val Ser Leu Gly 1 5 10 15 Glu Arg Ala Thr Ile Ser Cys Lys Ser Ser Gln Ser Leu Leu Tyr Ser 20 25 30 Ser Asn Asn Arg Asp Tyr Leu Ala Trp Tyr Gln Gln Lys Ala Gly Gln 35 40 45 Pro Pro Lys Leu Leu Phe Tyr Trp Ala Ser Thr Arg Glu Ser Gly Val 50 55 60 Pro Asp Arg Phe Gly Gly Ser Gly Ser Gly Thr His Phe Thr Leu Thr 65 70 75 80 Ile Tyr Asn Leu Gln Pro Glu Asp Val Ala Val Tyr Phe Cys Gln Gln 85 90 95 Tyr Phe Ser Pro Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile 100 105 110 Lys <210> 9380 <211> 124 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9380 Glu Val Gln Leu Leu Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Ala Val Tyr Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Cys Val 35 40 45 Ser Phe Ile Ser Gly Gly Gly Glu Thr Thr Asp Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 65 70 75 80 Leu Gln Met Asn Gly Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Lys Ser Pro Asp Ala Thr Phe Leu Trp Phe Gly Glu Pro Phe Gly 100 105 110 Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9381 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9381 Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Val Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Asn 20 25 30 Val Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Ser Leu Leu Ile 35 40 45 Tyr Gly Ala Ser Thr Arg Ala Thr Gly Thr Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Gly Phe Thr Leu Thr Ile Thr Ser Leu Gln Ser 65 70 75 80 Glu Asp Phe Gly Val Tyr Tyr Cys Gln Gln Tyr Asn Asn Trp Arg Phe 85 90 95 Thr Phe Gly Pro Gly Thr Lys Val Glu Ile Lys 100 105 <210> 9382 <211> 125 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9382 Glu Val Gln Leu Leu Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Val Phe Ser Asp Tyr 20 25 30 Ser Met Asn Trp Val Arg Leu Ala Pro Gly Lys Gly Leu Ala Trp Val 35 40 45 Ser Val Val Gly Val Asp Ala Val Thr Lys Phe Tyr Glu Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Ile Tyr 65 70 75 80 Leu Gln Met Asn Asn Leu Arg Ala Glu Asp Thr Ala Val Tyr His Cys 85 90 95 Ala Lys Ser Gln Pro Val Ser Arg Met Gly Arg Phe Phe Val Gly Leu 100 105 110 Asp Val Trp Gly Gln Gly Thr Thr Val Thr Val Ser Ser 115 120 125 <210> 9383 <211> 113 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9383 Glu Ile Val Met Thr Gln Ser Pro Asp Ser Leu Thr Val Ser Leu Gly 1 5 10 15 Glu Arg Ala Thr Ile Ser Cys Lys Ser Ser Gln Ser Leu Leu Tyr Ser 20 25 30 Ser Asn Asn Arg Asp Tyr Leu Ala Trp Tyr Gln Gln Lys Ala Gly Gln 35 40 45 Pro Pro Lys Leu Leu Phe Tyr Trp Ala Ser Thr Arg Glu Ser Gly Val 50 55 60 Pro Asp Arg Phe Gly Gly Ser Gly Ser Gly Thr His Phe Thr Leu Thr 65 70 75 80 Ile Tyr Asn Leu Gln Pro Glu Asp Val Ala Val Tyr Phe Cys Gln Gln 85 90 95 Tyr Phe Ser Pro Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile 100 105 110 Lys <210> 9384 <211> 122 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9384 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Lys Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Ser Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ser Ser Ile Ser Ser Thr Ser Ser Tyr Ile Tyr Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Arg Arg Ala Ala Thr Gly Thr Glu Phe Tyr Phe Asp Tyr Trp 100 105 110 Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9385 <211> 110 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9385 Gln Ser Val Leu Thr Gln Pro Pro Ser Val Ser Ala Ala Pro Gly Gln 1 5 10 15 Lys Val Thr Ile Ser Cys Ser Gly Ser Ser Ser Asn Ile Gly Asn Asn 20 25 30 Tyr Val Ser Trp Tyr Gln Gln Leu Pro Gly Thr Ala Pro Lys Leu Leu 35 40 45 Ile Tyr Asp Asn Asn Lys Arg Pro Ser Gly Ile Pro Asp Arg Phe Ser 50 55 60 Gly Ser Lys Ser Gly Thr Ser Ala Thr Leu Gly Ile Thr Gly Leu Gln 65 70 75 80 Thr Gly Asp Glu Ala Asp Tyr Tyr Cys Gly Thr Trp Asp Ser Ser Leu 85 90 95 Ser Ala Val Leu Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 110 <210> 9386 <211> 119 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9386 Gln Ala His Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Gly Thr Phe Asn Ser His 20 25 30 Ala Ile Gly Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Met 35 40 45 Gly Arg Ile Val Pro Ile Arg Lys Thr Thr Thr Tyr Ala Pro Gln Leu 50 55 60 Gln Gly Arg Leu Thr Leu Thr Ala Asp Thr Ser Thr Ser Thr Leu Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Ser Ala Arg Tyr Tyr Cys 85 90 95 Ala Arg Val Ile Leu Ser Gly Arg Gly Phe Asp Ile Trp Gly Gln Gly 100 105 110 Ser Leu Val Ala Val Ser Ser 115 <210> 9387 <211> 104 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9387 Asp Ile Gln Met Thr Gln Ser Pro Ser Ala Leu Ala Ala Ser Leu Gly 1 5 10 15 Asp Arg Val Ile Ile Thr Cys Gln Ala Ser His Asp Ile Gly His Asn 20 25 30 Leu Asn Trp Tyr Gln Gln Arg Pro Gly Glu Ala Pro Gln Leu Leu Ile 35 40 45 Tyr Asp Val Ser Asn Leu Gln Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Phe Gly Phe Gly Thr Asn Phe Thr Phe Thr Ile Ser Gly Leu Gln Ser 65 70 75 80 Glu Asp Ile Gly Thr Tyr Tyr Cys Gln Gln Tyr Asp Ser Ile Phe Gly 85 90 95 Pro Gly Thr Lys Leu Glu Ile Lys 100 <210> 9388 <211> 127 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9388 Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Ala Ser Gly Gly Thr Phe Ser Ser Tyr 20 25 30 Ala Phe Ser Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Met 35 40 45 Gly Arg Ile Ile Leu Ile Leu Gly Ile Thr Asp Tyr Ala Pro Lys Phe 50 55 60 Gln Gly Arg Val Thr Ile Thr Ala Asp Lys Ser Thr Ser Thr Val Tyr 65 70 75 80 Met Glu Val Ser Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Glu Arg Pro Arg Asp Pro Ser Ser Asn Tyr Val Ala Tyr Tyr 100 105 110 Ala Met Asp Val Trp Gly Gln Gly Thr Ser Val Thr Val Ser Ser 115 120 125 <210> 9389 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9389 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Ser Ile Thr Thr Tyr 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Ala Gly Lys Ala Pro Asn Leu Leu Ile 35 40 45 Tyr Ala Pro Ser Asn Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Phe Gly Thr Tyr Tyr Cys Gln Gln Ser Tyr Ser Ser Pro Phe 85 90 95 Thr Phe Gly Pro Gly Thr Lys Val Asp Ile Lys 100 105 <210> 9390 <211> 124 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9390 Gln Val Gln Leu Gln Gln Ser Gly Pro Gly Leu Val Arg Pro Ser Gly 1 5 10 15 Thr Leu Ser Leu Thr Cys Gly Val Ser Gly Gly Ser Ile Ser Ser Pro 20 25 30 Asn Trp Trp Ser Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp 35 40 45 Ile Gly Glu Val Tyr Pro Thr Gly Asn Thr Tyr Tyr Asn Pro Ser Leu 50 55 60 Lys Ser Arg Val Thr Ile Ser Ile Glu Glu Ser Lys Asn Glu Phe Ser 65 70 75 80 Leu Asn Leu Ser Ser Val Thr Ala Ala Asp Met Gly Ile Tyr Tyr Cys 85 90 95 Ala Arg Gly Val Val Gly Ala Ser Asp Phe Tyr Tyr Tyr Gly Met Asp 100 105 110 Val Trp Gly Gln Gly Thr Ala Val Thr Val Ser Ser 115 120 <210> 9391 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9391 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Glu Thr Ile Ser Asn Phe 20 25 30 Leu Asn Trp Tyr Leu Gln Arg Pro Gly Lys Ala Pro Gln Val Leu Ile 35 40 45 Tyr Ser Ala Ala Arg Leu Gln Ser Gly Val Pro Ser Arg Phe Arg Ala 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Thr Ser Leu Gln Leu 65 70 75 80 Glu Asp Phe Gly Val Tyr Tyr Cys Gln Gln Ser Phe Asn Thr Pro Arg 85 90 95 Thr Phe Gly Gln Gly Thr Arg Val Glu Ile Lys 100 105 <210> 9392 <211> 117 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9392 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Thr Leu Ser Cys Ala Ala Ser Gly Leu Thr Ile Arg Asn Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Met Glu Glu Asp Gly Ser Glu Lys Asn Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Ile Ile Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser Trp Gly Gln Gly Thr Val 100 105 110 Val Thr Val Ser Ser 115 <210> 9393 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9393 Glu Ile Val Leu Thr Gln Ser Pro Gly Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Glu Ser Val Ser Ser Asn 20 25 30 Tyr Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu 35 40 45 Ile Tyr Asp Ala Ser Ser Arg Ala Thr Gly Ile Pro Asp Arg Phe Ser 50 55 60 Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Lys Leu Glu 65 70 75 80 Pro Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Ala Arg Ala Pro 85 90 95 Asp Thr Phe Ala Gln Gly Thr Arg Leu Glu Ile Lys 100 105 <210> 9394 <211> 125 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9394 Gln Val Gln Leu Gln Gln Trp Gly Ala Gly Leu Leu Lys Pro Ala Glu 1 5 10 15 Thr Leu Ser Leu Thr Cys Ala Val His Gly Gly Ser Phe Thr Asp Ser 20 25 30 Tyr Trp Ser Trp Ile Arg Gln Thr Pro Gly Gln Gly Leu Glu Trp Leu 35 40 45 Gly Glu Val Asn His Ser Gly Ser Thr Asn Tyr Ser Pro Ser Leu Lys 50 55 60 Thr Arg Val Ala Ile Ser Ile Asp Thr Ser Lys Asn Gln Val Ser Leu 65 70 75 80 Arg Leu Thr Ser Val Ser Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 85 90 95 Arg Gly Met Ala Val Arg Gly Arg Gln Leu Tyr Leu Leu Gly Gly Tyr 100 105 110 Asp Leu Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 125 <210> 9395 <211> 106 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9395 Glu Val Val Met Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Tyr Ile Asn 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Pro Pro Arg Leu Leu Ile 35 40 45 Tyr Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Glu Phe Thr Leu Thr Ile Ser Ser Leu Glu Ser 65 70 75 80 Glu Asp Phe Gly Thr Tyr Tyr Cys Gln Gln Tyr Asn His Trp Arg Thr 85 90 95 Phe Gly Gln Gly Thr Lys Val Glu Ile Lys 100 105 <210> 9396 <211> 118 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9396 Ser Gln Leu Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Phe Gly Asp Ser Ile Tyr Gly Tyr 20 25 30 Tyr Trp Thr Trp Ile Arg Gln Pro Pro Gly Arg Gly Leu Glu Trp Ile 35 40 45 Gly Ser Val Tyr His Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Met 50 55 60 Ser Arg Val Thr Ile Ser Val Asp Thr Ser Glu Lys Gln Phe Ser Leu 65 70 75 80 Lys Val Thr Ser Val Thr Gly Ala Asp Thr Ala Val Tyr Phe Cys Ala 85 90 95 Arg Gly Leu Ala Gly Gly Gly Tyr Phe Asp Ala Trp Gly Gln Gly Asn 100 105 110 Leu Val Ala Val Ser Ser 115 <210> 9397 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9397 Asp Val Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Pro Gly Ile Asn Thr Tyr 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Val Pro Asp Leu Leu Ile 35 40 45 Tyr Gly Ala Ser Thr Leu Arg Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Leu 65 70 75 80 Glu Asp Val Ala Thr Tyr Tyr Cys Gln Ala Tyr Tyr Val Gly Leu Gly 85 90 95 Thr Phe Gly Gln Gly Thr Lys Val Glu Ile Lys 100 105 <210> 9398 <211> 119 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9398 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Arg Pro Gly Glu 1 5 10 15 Ser Leu Arg Leu Ser Cys Val Gly Ser Gly Phe Pro Phe Gly Gly Tyr 20 25 30 Gly Met Ser Trp Val Arg Gln Val Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ser Gly Ile Asn Trp Ser Ala Asp Arg Arg Val Tyr Ala Asp Phe Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Tyr Pro Lys Lys Ser Val Ser 65 70 75 80 Leu Gln Met Asp Asn Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys 85 90 95 Ala Arg Glu Arg Thr Ser Arg Arg Asp Phe Asp Phe Trp Gly Gln Gly 100 105 110 Thr Leu Val Thr Val Ser Ser 115 <210> 9399 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9399 Ser Phe Val Leu Thr Gln Pro Pro Ser Val Ser Val Ala Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Pro Cys Ala Lys Asn Tyr Arg Gly Ser Gln Thr Val 20 25 30 His Trp Tyr Gln Arg Lys Pro Gly Gln Ala Pro Val Leu Val Ile Asn 35 40 45 Ser Asp Asp Asp Arg Pro Ser Gly Ile Ser Glu Arg Phe Ser Gly Ser 50 55 60 Asn Ser Gly Asn Thr Ala Thr Leu Thr Ile Ser Arg Val Glu Ala Gly 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Val Trp Asp Pro Ser Ser Asp Gln 85 90 95 Ala Leu Phe Ala Gly Gly Thr Thr Leu Thr Val Leu 100 105 <210> 9400 <211> 121 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9400 Glu Val Gln Leu Val Asp Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Thr Ser Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Ile Lys Gln Asp Gly Ser Glu Lys Asp Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Ser Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Asp Leu Gly Ser Gly Ser Tyr His Leu Phe Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9401 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9401 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9402 <211> 126 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9402 Gln Val Gln Leu Val Gln Ser Gly Ser Glu Leu Lys Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Val Ser Cys Lys Thr Ser Gly Tyr Thr Phe Thr Ser Tyr 20 25 30 Ala Ile Asn Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Ile 35 40 45 Gly Trp Ile Asn Ile Asn Thr Gly Asn Pro Thr Tyr Ala Gln Gly Phe 50 55 60 Thr Gly Arg Val Asp Phe Ser Leu Asp Thr Ser Val Ser Thr Ala Tyr 65 70 75 80 Leu Gln Ile Arg Ser Leu Lys Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Asp Arg Gly Ile Ala Ala Arg Arg Gly Tyr Tyr Tyr Tyr Gly 100 105 110 Met Asp Val Trp Gly Gln Gly Thr Thr Val Thr Val Ser Ser 115 120 125 <210> 9403 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9403 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Ser Ile Thr Thr Tyr 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Ala Gly Lys Ala Pro Asn Leu Leu Ile 35 40 45 Tyr Ala Pro Ser Asn Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Phe Gly Thr Tyr Tyr Cys Gln Gln Ser Tyr Ser Ser Pro Phe 85 90 95 Thr Phe Gly Pro Gly Thr Lys Val Asp Ile Lys 100 105 <210> 9404 <211> 119 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9404 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Arg Pro Gly Glu 1 5 10 15 Ser Leu Arg Leu Ser Cys Val Gly Ser Gly Phe Pro Phe Gly Gly Tyr 20 25 30 Gly Met Ser Trp Val Arg Gln Val Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ser Gly Ile Asn Trp Ser Ala Asp Arg Arg Val Tyr Ala Asp Phe Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Tyr Pro Lys Lys Ser Val Ser 65 70 75 80 Leu Gln Met Asp Asn Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys 85 90 95 Ala Arg Glu Arg Thr Ser Arg Arg Asp Phe Asp Phe Trp Gly Gln Gly 100 105 110 Thr Leu Val Thr Val Ser Ser 115 <210> 9405 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9405 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9406 <211> 121 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9406 Glu Val Gln Leu Val Asp Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Thr Ser Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Ile Lys Gln Asp Gly Ser Glu Lys Asp Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Ser Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Asp Leu Gly Ser Gly Ser Tyr His Leu Phe Asp Tyr Trp Gly 100 105 110 Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9407 <211> 110 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9407 Gln Ser Val Leu Thr Gln Pro Pro Ser Val Ser Ala Ala Pro Gly Gln 1 5 10 15 Lys Val Thr Ile Ser Cys Ser Gly Ser Ser Ser Asn Ile Gly Asn Asn 20 25 30 Tyr Val Ser Trp Tyr Gln Gln Leu Pro Gly Thr Ala Pro Lys Leu Leu 35 40 45 Ile Tyr Asp Asn Asn Lys Arg Pro Ser Gly Ile Pro Asp Arg Phe Ser 50 55 60 Gly Ser Lys Ser Gly Thr Ser Ala Thr Leu Gly Ile Thr Gly Leu Gln 65 70 75 80 Thr Gly Asp Glu Ala Asp Tyr Tyr Cys Gly Thr Trp Asp Asn Ser Leu 85 90 95 Ser Ala Trp Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 110 <210> 9408 <211> 112 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9408 Gln Val Gln Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Ser Gly Gly Ser Ile Ser Ser Tyr 20 25 30 Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu Glu Tyr Ile 35 40 45 Gly Tyr Ile Tyr Tyr Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Lys 50 55 60 Ser Arg Val Thr Ile Ser Val Asp Thr Ser Lys Asn Gln Leu Ser Leu 65 70 75 80 Lys Leu Arg Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 85 90 95 Arg Gly Phe Asp Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 100 105 110 <210> 9409 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9409 Glu Ile Val Leu Thr Gln Ser Pro Ala Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Tyr 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu Ile 35 40 45 Phe Asp Ala Ser Asn Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Glu Pro 65 70 75 80 Glu Asp Phe Ala Val Tyr Phe Cys Gln Gln Arg Ser Ser Trp Gln Gly 85 90 95 Ile Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys 100 105 <210> 9410 <211> 124 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9410 Gln Val Gln Leu Val Gln Ser Gly Ser Glu Leu Lys Lys Pro Gly Ala 1 5 10 15 Ser Val Lys Ile Ser Cys Lys Thr Ser Gly Tyr Asn Phe Thr Asn His 20 25 30 Pro Ile Asn Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Met 35 40 45 Gly Trp Ile Asn Thr Asn Thr Gly Asn Pro Thr Tyr Gly Gln Ala Phe 50 55 60 Thr Gly Arg Phe Val Phe Ser Phe Asp Thr Ser Val Gly Thr Ala Tyr 65 70 75 80 Leu His Ile Ser Gly Leu Gln Pro Gly Asp Thr Ala Phe Tyr Tyr Cys 85 90 95 Val Arg Glu Asp Leu Arg Leu Arg Gln Val Trp Trp Arg Trp Phe Asp 100 105 110 Pro Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9411 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9411 Glu Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Ser Cys Arg Ala Ser Gln Ser Val Gly Gly His 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Val Leu Ile 35 40 45 His Ala Ala Ser Ser Leu Glu Gly Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Tyr Thr Leu Thr Ile Thr Asn Leu Gln Pro 65 70 75 80 Glu Asp Phe Ala Thr Tyr Phe Cys Gln Gln Ser Arg Asn Ser Pro Ala 85 90 95 Thr Phe Gly Gln Gly Thr Lys Val Glu Met Lys 100 105 <210> 9412 <211> 121 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9412 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Ala Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Val Ile Ser Tyr Asp Gly Ser Asn Lys Tyr Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gly Lys Leu Gly Ile Val Gly Asp Ala Phe Asp Ile Trp Gly 100 105 110 Gln Gly Thr Met Val Thr Val Ser Ser 115 120 <210> 9413 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9413 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Gln Ala Ser Gln Asp Ile Ser Asn Tyr 20 25 30 Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Asp Ala Ser Asn Leu Glu Thr Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Phe Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Ile Ala Thr Tyr Tyr Cys Gln Gln Tyr Asp Asn Leu Pro Leu 85 90 95 Thr Phe Gly Pro Gly Thr Lys Val Asp Ile Lys 100 105 <210> 9414 <211> 118 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9414 Ser Gln Leu Leu Gln Glu Ser Gly Pro Gly Leu Val Lys Pro Ser Glu 1 5 10 15 Thr Leu Ser Leu Thr Cys Thr Val Phe Gly Asp Ser Ile Tyr Gly Tyr 20 25 30 Tyr Trp Thr Trp Ile Arg Gln Pro Pro Gly Arg Gly Leu Glu Trp Ile 35 40 45 Gly Ser Val Tyr His Ser Gly Ser Thr Asn Tyr Asn Pro Ser Leu Met 50 55 60 Ser Arg Val Thr Ile Ser Val Asp Thr Ser Glu Lys Gln Phe Ser Leu 65 70 75 80 Lys Val Thr Ser Val Thr Gly Ala Asp Thr Ala Val Tyr Phe Cys Ala 85 90 95 Arg Gly Leu Ala Gly Gly Gly Tyr Phe Asp Ala Trp Gly Gln Gly Asn 100 105 110 Leu Val Ala Val Ser Ser 115 <210> 9415 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9415 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9416 <211> 127 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9416 Gln Val Gln Leu Glu Gln Ser Gly Ala Glu Val Lys Arg Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Gly Asp Gly Asp Thr Phe Ser Thr Tyr 20 25 30 Ala Ile Thr Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Met 35 40 45 Gly Arg Ile Ile Pro Gly Leu Asp Leu Val Asp Asn Gln Gln Lys Phe 50 55 60 Gln Asp Arg Leu Thr Ile Thr Ala Asp Lys Ser Thr Thr Thr Ala Tyr 65 70 75 80 Met Glu Leu Arg Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gly Arg Arg Tyr Asp Phe Leu Asp Gly Gln Tyr Thr Ser Trp 100 105 110 Tyr Phe Asp Ile Trp Gly Arg Gly Thr Leu Val Thr Val Ser Ser 115 120 125 <210> 9417 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9417 Glu Ile Val Leu Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Val Thr Leu Ser Cys Arg Ala Ser Gln Thr Val Asn Asn Asn 20 25 30 Leu Asn Trp Leu Gln His Lys Pro Gly Gln Ala Pro Arg Leu Val Ile 35 40 45 Ile Gly Thr Ser Thr Arg Ala Ser Gly Val Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Glu Phe Thr Leu Thr Ile Ser Ser Leu Gln Ser 65 70 75 80 Glu Asp Tyr Ala Ile Tyr Tyr Cys Gln Gln Tyr Tyr Glu Trp Pro Pro 85 90 95 Ile Thr Tyr Gly Gln Gly Thr Arg Leu Glu Ile 100 105 <210> 9418 <211> 122 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9418 Glu Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ala 1 5 10 15 Thr Val Lys Ile Ser Cys Lys Val Ser Gly Tyr Thr Phe Thr Asp Tyr 20 25 30 Tyr Met His Trp Val Gln Gln Ala Pro Gly Lys Gly Leu Glu Trp Met 35 40 45 Gly Leu Val Asp Pro Glu Asp Gly Glu Thr Ile Tyr Ala Glu Lys Phe 50 55 60 Gln Gly Arg Val Thr Ile Thr Ala Asp Thr Ser Thr Asp Thr Ala Tyr 65 70 75 80 Met Glu Leu Ser Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Thr Val Ser Arg Trp Tyr Tyr Tyr Tyr Tyr Gly Met Asp Val Trp 100 105 110 Gly Gln Gly Thr Thr Val Thr Val Ser Ser 115 120 <210> 9419 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9419 Glu Ile Val Leu Thr Gln Ser Pro Gly Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Ser 20 25 30 Tyr Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu 35 40 45 Ile Tyr Gly Ala Ser Ser Arg Ala Thr Gly Ile Pro Asp Arg Phe Ser 50 55 60 Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Arg Leu Glu 65 70 75 80 Pro Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Gly Ser Ser Tyr 85 90 95 Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 <210> 9420 <211> 120 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9420 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Asn Leu Ser Asn Tyr 20 25 30 Ala Met His Trp Val Arg Gln Ala Ser Gly Lys Gly Leu Glu Trp Val 35 40 45 Ser Leu Ile Ser Tyr Asp Gly Ser Ile Lys Tyr Tyr Thr Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Val Ser Gly Asp Asn Ser Lys Asn Thr Leu Phe 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Pro Asp Asp Ser Ala Leu Tyr Tyr Cys 85 90 95 Val Arg Gly Gly Val Ser Gly Pro Asn Ser Phe Asp Met Trp Gly Gln 100 105 110 Gly Thr Thr Val Thr Val Ser Ser 115 120 <210> 9421 <211> 112 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9421 Asp Val Val Met Thr Gln Ser Pro Leu Ser Leu Pro Val Thr Leu Gly 1 5 10 15 Gln Pro Ala Ser Ile Ser Cys Arg Ser Ser Gln Ser Leu Val Tyr Ser 20 25 30 Asp Gly Asn Thr Tyr Val Asn Trp Phe Gln Gln Arg Pro Gly Gln Ser 35 40 45 Pro Arg Arg Leu Ile Tyr Gln Val Ser Ile Arg Ala Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Ala Leu Lys Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Ile Tyr Tyr Cys Met Gln Gly 85 90 95 Thr His Trp Pro Val Thr Phe Gly Gln Gly Thr Lys Val Glu Ile Lys 100 105 110 <210> 9422 <211> 125 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9422 Glu Val Gln Leu Leu Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Val Phe Ser Asp Tyr 20 25 30 Ser Met Asn Trp Val Arg Leu Ala Pro Gly Lys Gly Leu Ala Trp Val 35 40 45 Ser Val Val Gly Val Asp Ala Val Thr Lys Phe Tyr Glu Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Ile Tyr 65 70 75 80 Leu Gln Met Asn Asn Leu Arg Ala Glu Asp Thr Ala Val Tyr His Cys 85 90 95 Ala Lys Ser Gln Pro Val Ser Arg Met Gly Arg Phe Phe Val Gly Leu 100 105 110 Asp Val Trp Gly Gln Gly Thr Thr Val Thr Val Ser Ser 115 120 125 <210> 9423 <211> 110 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9423 Gln Ser Ala Leu Thr Gln Pro Pro Ser Ala Ser Gly Ser Pro Gly Gln 1 5 10 15 Ser Val Thr Ile Ser Cys Thr Gly Ser Ser Asn Asp Val Gly Arg Tyr 20 25 30 Asn Tyr Val Ser Trp Tyr Gln His His Pro Gly Lys Ala Pro Arg Leu 35 40 45 Met Ile Ser Glu Val Val Lys Arg Pro Ser Gly Val Pro Asp Arg Phe 50 55 60 Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Val Ser Gly Leu 65 70 75 80 Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Ser Ser Tyr Gly Gly Asn 85 90 95 Asn Ile Leu Leu Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 110 <210> 9424 <211> 118 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9424 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ile Ser Tyr 20 25 30 Thr Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Leu Ile Ser Tyr Asp Gly Tyr Asn Lys Tyr Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 65 70 75 80 Val Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys 85 90 95 Ala Arg Glu Gly Ser Pro Glu Ala Phe Asp Tyr Trp Gly Gln Gly Thr 100 105 110 Leu Val Thr Val Ser Ser 115 <210> 9425 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9425 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9426 <211> 117 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9426 Glu Met Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Asp Tyr 20 25 30 Tyr Met Tyr Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Val Trp Val 35 40 45 Ser Arg Ile Lys Pro Asp Gly Thr Gly Thr Ser Tyr Ala Asp Ser Val 50 55 60 Arg Gly Arg Phe Thr Val Ser Arg Asp Asn Ala Lys Asn Thr Leu Asn 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Val Ala Tyr Asn Trp Asn Tyr Asp Phe Cys Trp Gly Gln Gly Thr Leu 100 105 110 Val Thr Val Ser Ala 115 <210> 9427 <211> 112 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9427 Asp Val Thr Val Thr Gln Ser Pro Leu Ser Leu Pro Val Thr Leu Gly 1 5 10 15 Gln Pro Ala Ser Ile Ser Cys Arg Ser Ser Gln Ser Leu Val Tyr Ser 20 25 30 Asp Gly Asn Thr Tyr Leu Asn Trp Phe Gln Gln Arg Pro Gly Gln Ser 35 40 45 Pro Arg Arg Leu Ile Tyr Gln Val Ser Asn Arg Asp Ser Gly Val Pro 50 55 60 Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile 65 70 75 80 Ser Arg Val Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln Gly 85 90 95 Ser Tyr Trp Pro Phe Thr Phe Gly Pro Gly Thr Lys Val Asp Ile Lys 100 105 110 <210> 9428 <211> 125 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9428 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ser Ala Ser Gly Phe Ser Tyr Ser Asn Tyr 20 25 30 Trp Met Thr Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Leu Arg Arg Asp Gly Ser Val Glu His Tyr Val Asp Ser Val 50 55 60 Arg Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asp Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Asp Leu Ser Pro Gly Gly Leu Gly Ala Tyr Tyr Asp Val Phe 100 105 110 Asp Ile Trp Gly Gln Gly Thr Met Val Thr Val Ser Ser 115 120 125 <210> 9429 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9429 Ala Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Leu Gly 1 5 10 15 Asp Arg Ile Ser Ile Thr Cys Arg Ala Ser Gln Gly Ile Gly Asn Glu 20 25 30 Leu Gly Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Arg Leu Leu Ile 35 40 45 Tyr Ala Gly Ser Thr Leu Gln Gly Gly Val Pro Pro Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Ala 65 70 75 80 Glu Asp Phe Ala Thr Tyr Tyr Cys Leu Gln Asp Tyr Ala Tyr Pro Arg 85 90 95 Thr Phe Gly Pro Gly Thr Lys Val Glu Val Lys 100 105 <210> 9430 <211> 125 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9430 Glu Val Gln Leu Leu Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Val Phe Ser Asp Tyr 20 25 30 Ser Met Asn Trp Val Arg Leu Ala Pro Gly Lys Gly Leu Ala Trp Val 35 40 45 Ser Val Val Gly Val Asp Ala Val Thr Lys Phe Tyr Glu Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Ile Tyr 65 70 75 80 Leu Gln Met Asn Asn Leu Arg Ala Glu Asp Thr Ala Val Tyr His Cys 85 90 95 Ala Lys Ser Gln Pro Val Ser Arg Met Gly Arg Phe Phe Val Gly Leu 100 105 110 Asp Val Trp Gly Gln Gly Thr Thr Val Thr Val Ser Ser 115 120 125 <210> 9431 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9431 Glu Ile Val Leu Thr Gln Ser Pro Gly Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Ser 20 25 30 Tyr Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu 35 40 45 Ile Tyr Gly Ala Ser Ser Arg Ala Thr Gly Ile Pro Asp Arg Phe Ser 50 55 60 Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Arg Leu Glu 65 70 75 80 Pro Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Gly Ser Ser Tyr 85 90 95 Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 <210> 9432 <211> 122 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9432 Glu Val Gln Leu Leu Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Ala Met Ser Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ser Ala Ile Ser Gly Ser Gly Gly Ser Thr Tyr Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Lys Asp Gln His Met Val Arg Gly Ala Ile Gly Phe Asp Tyr Trp 100 105 110 Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9433 <211> 106 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9433 Glu Ile Val Met Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Asn 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu Ile 35 40 45 Tyr Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Glu Phe Thr Leu Thr Ile Ser Ser Leu Gln Ser 65 70 75 80 Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Asn Asn Trp Arg Thr 85 90 95 Phe Gly Gln Gly Thr Lys Val Glu Ile Lys 100 105 <210> 9434 <211> 120 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9434 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Ile Phe Ser Asn Phe 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Ile Gln Gln Asp Gly Ser Glu Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Thr Asp Leu Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9435 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9435 Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Val Ser Ala Ser Val Gly 1 5 10 15 Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile Asn Ser Trp 20 25 30 Leu Ala Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45 Tyr Ala Ala Ser Ser Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro 65 70 75 80 Glu Asp Phe Ala Thr Tyr Tyr Cys Gln Gln Ala His Ser Phe Pro Ile 85 90 95 Thr Phe Gly Gln Gly Thr Arg Leu Glu Ile Lys 100 105 <210> 9436 <211> 125 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9436 Glu Val Gln Leu Leu Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Val Phe Ser Asp Tyr 20 25 30 Ser Met Asn Trp Val Arg Leu Ala Pro Gly Lys Gly Leu Ala Trp Val 35 40 45 Ser Val Val Gly Val Asp Ala Val Thr Lys Phe Tyr Glu Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Ile Tyr 65 70 75 80 Leu Gln Met Asn Asn Leu Arg Ala Glu Asp Thr Ala Val Tyr His Cys 85 90 95 Ala Lys Ser Gln Pro Val Ser Arg Met Gly Arg Phe Phe Val Gly Leu 100 105 110 Asp Val Trp Gly Gln Gly Thr Thr Val Thr Val Ser Ser 115 120 125 <210> 9437 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9437 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9438 <211> 118 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9438 Gln Val Gln Leu Val Gln Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Thr Ala Ser Gly Phe Thr Phe Ser Asn Tyr 20 25 30 Ala Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Gly 35 40 45 Ala Val Ile Ser Tyr Asp Gly Thr Ile Thr Leu Tyr Glu Asp Ser Met 50 55 60 Arg Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Arg Asp Thr Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Pro Asp Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Gly Arg Asp Leu Ser Gly Gly Gly Leu Asp Val Trp Gly Gln Gly Thr 100 105 110 Thr Val Thr Val Ser Ser 115 <210> 9439 <211> 110 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9439 Gln Ser Ala Leu Thr Gln Ala Arg Ser Val Ser Gly Ser Pro Gly Gln 1 5 10 15 Ser Val Thr Val Ser Cys Thr Gly Ser Ser Asn Asp Val Gly Gly His 20 25 30 Asn Tyr Val Ser Trp Tyr Gln His Ser Pro Gly Lys Ala Pro Lys Leu 35 40 45 Ile Ile Tyr Asp Val Thr Lys Arg Pro Ser Gly Val Pro Asp Arg Phe 50 55 60 Ser Gly Ser Lys Ser Gly Asp Thr Ala Ser Leu Thr Ile Ser Gly Leu 65 70 75 80 Gln Ala Asp Asp Glu Gly Asp Tyr Tyr Cys Cys Ser Tyr Lys Ser Thr 85 90 95 Tyr Asp Tyr Val Phe Gly Ser Gly Thr Thr Val Ser Val Leu 100 105 110 <210> 9440 <211> 121 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9440 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ile Tyr 20 25 30 Ala Ile His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Met 35 40 45 Ala Val Ile Ser Tyr Asp Gly Asn Asn Gln Tyr Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Thr Asp Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Ser Glu Gly Gly Gly Tyr His Asp Ala Phe Asp Ile Trp Gly 100 105 110 Gln Gly Thr Met Val Thr Val Ser Ser 115 120 <210> 9441 <211> 111 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9441 Gln Leu Val Leu Thr Gln Ser Pro Ser Ala Ser Ala Ser Leu Gly Ala 1 5 10 15 Ser Val Lys Leu Thr Cys Thr Leu Ser Ser Gly His Ser Ser Tyr Ala 20 25 30 Ile Ala Trp His Gln Gln Gln Pro Glu Lys Gly Pro Arg Tyr Leu Met 35 40 45 Lys Leu Asn Ser Asp Gly Ser His Asn Lys Gly Asp Gly Ile Pro Asp 50 55 60 Arg Phe Ser Gly Ser Ser Ser Gly Ala Glu Arg Tyr Leu Thr Ile Ser 65 70 75 80 Ser Leu Gln Ser Glu Asp Glu Ala Asp Tyr Phe Cys Gln Thr Trp Gly 85 90 95 Thr Gly Ile His Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 110 <210> 9442 <211> 118 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9442 Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro Gly Arg 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ile Ser Tyr 20 25 30 Thr Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Leu Ile Ser Tyr Asp Gly Tyr Asn Lys Tyr Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 65 70 75 80 Val Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Leu Tyr Tyr Cys 85 90 95 Ala Arg Glu Gly Ser Pro Glu Ala Phe Asp Tyr Trp Gly Gln Gly Thr 100 105 110 Leu Val Thr Val Ser Ser 115 <210> 9443 <211> 109 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9443 Ser Phe Glu Leu Thr Gln Pro Pro Ser Leu Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Thr Cys Ser Gly Asp Ala Leu Ser Lys Gln Phe Thr 20 25 30 Tyr Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Val Leu Val Ile Tyr 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Glu Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala His Ser Ser Gly Phe Tyr 85 90 95 Arg Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9444 <211> 124 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9444 Glu Val Gln Leu Leu Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30 Ala Val Tyr Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Cys Val 35 40 45 Ser Phe Ile Ser Gly Gly Gly Glu Thr Thr Asp Tyr Ala Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr 65 70 75 80 Leu Gln Met Asn Gly Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Lys Ser Pro Asp Ala Thr Phe Leu Trp Phe Gly Glu Pro Phe Gly 100 105 110 Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9445 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9445 Glu Ile Val Leu Thr Gln Ser Pro Ala Thr Leu Ser Val Ser Pro Gly 1 5 10 15 Glu Arg Val Thr Leu Ser Cys Arg Ala Ser Gln Thr Val Asn Asn Asn 20 25 30 Leu Asn Trp Leu Gln His Lys Pro Gly Gln Ala Pro Arg Leu Val Ile 35 40 45 Ile Gly Thr Ser Thr Arg Ala Ser Gly Val Pro Ala Arg Phe Ser Gly 50 55 60 Ser Gly Ser Gly Thr Glu Phe Thr Leu Thr Ile Ser Ser Leu Gln Ser 65 70 75 80 Glu Asp Tyr Ala Ile Tyr Tyr Cys Gln Gln Tyr Tyr Glu Trp Pro Pro 85 90 95 Ile Thr Tyr Gly Gln Gly Thr Arg Leu Glu Ile 100 105 <210> 9446 <211> 127 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9446 Gln Val Gln Leu Glu Gln Ser Gly Ala Glu Val Lys Arg Pro Gly Ser 1 5 10 15 Ser Val Lys Val Ser Cys Lys Gly Asp Gly Asp Thr Phe Ser Thr Tyr 20 25 30 Ala Ile Thr Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Met 35 40 45 Gly Arg Ile Ile Pro Gly Leu Asp Leu Val Asp Asn Gln Gln Lys Phe 50 55 60 Gln Asp Arg Leu Thr Ile Thr Ala Asp Lys Ser Thr Thr Thr Ala Tyr 65 70 75 80 Met Glu Leu Arg Ser Leu Arg Ser Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gly Arg Arg Tyr Asp Phe Leu Asp Gly Gln Tyr Thr Ser Trp 100 105 110 Tyr Phe Asp Ile Trp Gly Arg Gly Thr Leu Val Thr Val Ser Ser 115 120 125 <210> 9447 <211> 113 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9447 Glu Ile Val Met Thr Gln Ser Pro Asp Ser Leu Thr Val Ser Leu Gly 1 5 10 15 Glu Arg Ala Thr Ile Ser Cys Lys Ser Ser Gln Ser Leu Leu Tyr Ser 20 25 30 Ser Asn Asn Arg Asp Tyr Leu Ala Trp Tyr Gln Gln Lys Ala Gly Gln 35 40 45 Pro Pro Lys Leu Leu Phe Tyr Trp Ala Ser Thr Arg Glu Ser Gly Val 50 55 60 Pro Asp Arg Phe Gly Gly Ser Gly Ser Gly Thr His Phe Thr Leu Thr 65 70 75 80 Ile Tyr Asn Leu Gln Pro Glu Asp Val Ala Val Tyr Phe Cys Gln Gln 85 90 95 Tyr Phe Ser Pro Pro Tyr Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile 100 105 110 Lys <210> 9448 <211> 120 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9448 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Ile Phe Ser Asn Phe 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Ile Gln Gln Asp Gly Ser Glu Lys Tyr Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Thr Ile Ser Thr Asp Leu Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr Trp Gly Gln 100 105 110 Gly Thr Leu Val Thr Val Ser Ser 115 120 <210> 9449 <211> 107 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9449 Glu Ile Val Leu Thr Gln Ser Pro Gly Thr Leu Ser Leu Ser Pro Gly 1 5 10 15 Glu Arg Ala Thr Leu Ser Cys Arg Ala Ser Gln Ser Val Ser Ser Ser 20 25 30 Tyr Leu Ala Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Arg Leu Leu 35 40 45 Ile Tyr Gly Ala Ser Ser Arg Ala Thr Gly Ile Pro Asp Arg Phe Ser 50 55 60 Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Arg Leu Glu 65 70 75 80 Pro Glu Asp Phe Ala Val Tyr Tyr Cys Gln Gln Tyr Gly Ser Ser Tyr 85 90 95 Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105 <210> 9450 <211> 117 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9450 Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Gly 1 5 10 15 Ser Leu Thr Leu Ser Cys Ala Ala Ser Gly Leu Thr Ile Arg Asn Tyr 20 25 30 Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45 Ala Asn Met Glu Glu Asp Gly Ser Glu Lys Asn Tyr Val Asp Ser Val 50 55 60 Lys Gly Arg Phe Ile Ile Ser Arg Asp Asp Ala Lys Asn Ser Leu Tyr 65 70 75 80 Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser Trp Gly Gln Gly Thr Val 100 105 110 Val Thr Val Ser Ser 115 <210> 9451 <211> 108 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9451 Ser Tyr Glu Leu Thr Gln Pro Pro Ser Val Ser Val Ser Pro Gly Gln 1 5 10 15 Thr Ala Arg Ile Ile Cys Ser Gly Asp Ala Leu Pro Lys Gln Asn Ala 20 25 30 Tyr Trp Tyr Gln Lys Lys Pro Gly Gln Ala Pro Val Leu Val Ile Phe 35 40 45 Lys Asp Ser Glu Arg Pro Ser Gly Ile Pro Gln Arg Phe Ser Gly Ser 50 55 60 Ser Ser Gly Thr Thr Val Thr Leu Thr Ile Ser Gly Val Gln Ala Glu 65 70 75 80 Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Ala Asp Ser Ser Gly Thr Tyr 85 90 95 Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 <210> 9452 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9452 Gly Asn Thr Phe Pro Thr Tyr Asp 1 5 <210> 9453 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9453 Ile Asn Thr Asn Thr Gly Ser Pro 1 5 <210> 9454 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9454 Ala Arg Glu Gly Tyr His Tyr Gly Met Asp Val 1 5 10 <210> 9455 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9455 Gly Gly Thr Phe Asn Ser His Ala 1 5 <210> 9456 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9456 Ile Val Pro Ile Arg Lys Thr Thr 1 5 <210> 9457 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9457 Ala Arg Val Ile Leu Ser Gly Arg Gly Phe Asp Ile 1 5 10 <210> 9458 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9458 Gly Phe Ile Phe Ser Asn Phe Trp 1 5 <210> 9459 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9459 Ile Gln Gln Asp Gly Ser Glu Lys 1 5 <210> 9460 <211> 13 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9460 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr 1 5 10 <210> 9461 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9461 Gly Phe Ile Phe Ser Asn Phe Trp 1 5 <210> 9462 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9462 Ile Gln Gln Asp Gly Ser Glu Lys 1 5 <210> 9463 <211> 13 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9463 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr 1 5 10 <210> 9464 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9464 Gly Phe Thr Phe Ser Ser Tyr Ala 1 5 <210> 9465 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9465 Ile Ser Gly Gly Gly Glu Thr Thr 1 5 <210> 9466 <211> 17 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9466 Ala Lys Ser Pro Asp Ala Thr Phe Leu Trp Phe Gly Glu Pro Phe Gly 1 5 10 15 Tyr <210> 9467 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9467 Gly Phe Thr Phe Ser Ser Tyr Ala 1 5 <210> 9468 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9468 Ile Ser Tyr Asp Gly Ser Asn Lys 1 5 <210> 9469 <211> 14 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9469 Ala Arg Asp Pro Asn Pro Met Val Leu Ala Tyr Phe Asp Tyr 1 5 10 <210> 9470 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9470 Gly Phe Thr Phe Ser Ser Tyr Ala 1 5 <210> 9471 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9471 Ile Ser Gly Gly Gly Glu Thr Thr 1 5 <210> 9472 <211> 17 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9472 Ala Lys Ser Pro Asp Ala Thr Phe Leu Trp Phe Gly Glu Pro Phe Gly 1 5 10 15 Tyr <210> 9473 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9473 Gly Phe Asn Leu Ser Asn Tyr Ala 1 5 <210> 9474 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9474 Ile Ser Tyr Asp Gly Ser Ile Lys 1 5 <210> 9475 <211> 13 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9475 Val Arg Gly Gly Val Ser Gly Pro Asn Ser Phe Asp Met 1 5 10 <210> 9476 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9476 Gly Leu Thr Ile Arg Asn Tyr Trp 1 5 <210> 9477 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9477 Met Glu Glu Asp Gly Ser Glu Lys 1 5 <210> 9478 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9478 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser 1 5 10 <210> 9479 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9479 Gly Gly Ser Ile Ser Ser Pro Asn Trp 1 5 <210> 9480 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9480 Val Tyr Pro Thr Gly Asn Thr 1 5 <210> 9481 <211> 17 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9481 Ala Arg Gly Val Val Gly Ala Ser Asp Phe Tyr Tyr Tyr Gly Met Asp 1 5 10 15 Val <210> 9482 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9482 Gly Asp Ser Ile Ser Arg Ser Asp Tyr His 1 5 10 <210> 9483 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9483 Ile Tyr Asn Asn Gly Asp Thr 1 5 <210> 9484 <211> 14 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9484 Ala Arg Asp Gly Tyr Ala Gly Asn Ser Glu Ala Leu Asp Tyr 1 5 10 <210> 9485 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9485 Gly Phe Ile Phe Ser Asn Phe Trp 1 5 <210> 9486 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9486 Ile Gln Gln Asp Gly Ser Glu Lys 1 5 <210> 9487 <211> 13 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9487 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr 1 5 10 <210> 9488 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9488 Gly Phe Ile Phe Ser Asn Phe Trp 1 5 <210> 9489 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9489 Ile Gln Gln Asp Gly Ser Glu Lys 1 5 <210> 9490 <211> 13 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9490 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr 1 5 10 <210> 9491 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9491 Lys Phe Thr Phe Ser Thr Tyr His 1 5 <210> 9492 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9492 Ile Ser Ala Asp Ser Thr Val Thr 1 5 <210> 9493 <211> 15 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9493 Ala Arg Gly Arg Ala Arg Gly Ser Asp His Thr Gly Phe Asp Ser 1 5 10 15 <210> 9494 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9494 Gly Phe Ile Phe Ser Asn Phe Trp 1 5 <210> 9495 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9495 Ile Gln Gln Asp Gly Ser Glu Lys 1 5 <210> 9496 <211> 13 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9496 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr 1 5 10 <210> 9497 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9497 Gly Phe Ile Phe Ser Asn Phe Trp 1 5 <210> 9498 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9498 Ile Gln Gln Asp Gly Ser Glu Lys 1 5 <210> 9499 <211> 13 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9499 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr 1 5 10 <210> 9500 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9500 Gly Gly Ser Ile Ser Ser Pro Asn Trp 1 5 <210> 9501 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9501 Val Tyr Pro Thr Gly Asn Thr 1 5 <210> 9502 <211> 17 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9502 Ala Arg Gly Val Val Gly Ala Ser Asp Phe Tyr Tyr Tyr Gly Met Asp 1 5 10 15 Val <210> 9503 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9503 Gly Gly Ser Ile Ser Ser Tyr Tyr 1 5 <210> 9504 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9504 Ile Tyr Tyr Ser Gly Ser Thr 1 5 <210> 9505 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9505 Ala Arg Gly Phe Asp Tyr 1 5 <210> 9506 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9506 Gly Leu Thr Ile Arg Asn Tyr Trp 1 5 <210> 9507 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9507 Met Glu Glu Asp Gly Ser Glu Lys 1 5 <210> 9508 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9508 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser 1 5 10 <210> 9509 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9509 Gly Phe Ile Phe Ser Asn Phe Trp 1 5 <210> 9510 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9510 Ile Gln Gln Asp Gly Ser Glu Lys 1 5 <210> 9511 <211> 13 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9511 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr 1 5 10 <210> 9512 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9512 Gly Gly Ser Ile Ser Ser Pro Asn Trp 1 5 <210> 9513 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9513 Val Tyr Pro Thr Gly Asn Thr 1 5 <210> 9514 <211> 17 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9514 Ala Arg Gly Val Val Gly Ala Ser Asp Phe Tyr Tyr Tyr Gly Met Asp 1 5 10 15 Val <210> 9515 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9515 Gly Leu Thr Ile Arg Asn Tyr Trp 1 5 <210> 9516 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9516 Met Glu Glu Asp Gly Ser Glu Lys 1 5 <210> 9517 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9517 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser 1 5 10 <210> 9518 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9518 Gly Phe Ile Phe Ser Asn Phe Trp 1 5 <210> 9519 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9519 Ile Gln Gln Asp Gly Ser Glu Lys 1 5 <210> 9520 <211> 13 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9520 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr 1 5 10 <210> 9521 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9521 Gly Gly Thr Phe Ile Asn Tyr Ala 1 5 <210> 9522 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9522 Ile Ile Pro Leu Leu Gly Val Ala 1 5 <210> 9523 <211> 20 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9523 Ala Arg Glu Tyr Ser Ser Ser Arg Pro Leu Phe Tyr Thr Tyr Asn Tyr 1 5 10 15 Gly Met Asp Val 20 <210> 9524 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9524 Gly Leu Thr Ile Arg Asn Tyr Trp 1 5 <210> 9525 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9525 Met Glu Glu Asp Gly Ser Glu Lys 1 5 <210> 9526 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9526 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser 1 5 10 <210> 9527 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9527 Gly Leu Thr Ile Arg Asn Tyr Trp 1 5 <210> 9528 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9528 Met Glu Glu Asp Gly Ser Glu Lys 1 5 <210> 9529 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9529 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser 1 5 10 <210> 9530 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9530 Gly Leu Thr Ile Arg Asn Tyr Trp 1 5 <210> 9531 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9531 Met Glu Glu Asp Gly Ser Glu Lys 1 5 <210> 9532 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9532 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser 1 5 10 <210> 9533 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9533 Gly Leu Thr Ile Arg Asn Tyr Trp 1 5 <210> 9534 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9534 Met Glu Glu Asp Gly Ser Glu Lys 1 5 <210> 9535 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9535 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser 1 5 10 <210> 9536 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9536 Gly Asp Thr Phe Ser Thr Tyr Ala 1 5 <210> 9537 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9537 Ile Ile Pro Gly Leu Asp Leu Val 1 5 <210> 9538 <211> 20 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9538 Ala Arg Gly Arg Arg Tyr Asp Phe Leu Asp Gly Gln Tyr Thr Ser Trp 1 5 10 15 Tyr Phe Asp Ile 20 <210> 9539 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9539 Gly Phe Thr Phe Ser Ser Tyr Ala 1 5 <210> 9540 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9540 Ile Ser Gly Gly Gly Glu Thr Thr 1 5 <210> 9541 <211> 17 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9541 Ala Lys Ser Pro Asp Ala Thr Phe Leu Trp Phe Gly Glu Pro Phe Gly 1 5 10 15 Tyr <210> 9542 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9542 Gly Tyr Gly Phe Ile Thr Tyr Trp 1 5 <210> 9543 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9543 Ile Tyr Pro Gly Asp Ser Glu Thr 1 5 <210> 9544 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9544 Ala Gly Gly Ser Gly Ile Ser Thr Pro Met Asp Val 1 5 10 <210> 9545 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9545 Gly Gly Ser Ile Ser Ser Gly Ser His Tyr 1 5 10 <210> 9546 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9546 Ile Tyr Thr Ser Gly Ser Thr 1 5 <210> 9547 <211> 17 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9547 Ala Arg Asp Ser Leu Ser Gly Ser Tyr His Tyr Tyr Tyr Gly Met Asp 1 5 10 15 Val <210> 9548 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9548 Gly Phe Thr Phe Ile Ser Tyr Thr 1 5 <210> 9549 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9549 Ile Ser Tyr Asp Gly Tyr Asn Lys 1 5 <210> 9550 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9550 Ala Arg Glu Gly Ser Pro Glu Ala Phe Asp Tyr 1 5 10 <210> 9551 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9551 Gly Phe Thr Phe Thr Asn His Trp 1 5 <210> 9552 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9552 Ile Lys Gln Asp Gly Ala Glu Lys 1 5 <210> 9553 <211> 17 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9553 Ala Arg Arg Ile Thr Met Ala Leu Ala Gly Trp Gly Trp Gly Met Asp 1 5 10 15 Val <210> 9554 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9554 Gly Tyr Thr Phe Thr Ser Tyr Ala 1 5 <210> 9555 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9555 Ile Asn Ile Asn Thr Gly Asn Pro 1 5 <210> 9556 <211> 19 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9556 Ala Arg Asp Arg Gly Ile Ala Ala Arg Arg Gly Tyr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val <210> 9557 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9557 Gly Asp Thr Phe Ser Thr Tyr Ala 1 5 <210> 9558 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9558 Ile Ile Pro Gly Leu Asp Leu Val 1 5 <210> 9559 <211> 20 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9559 Ala Arg Gly Arg Arg Tyr Asp Phe Leu Asp Gly Gln Tyr Thr Ser Trp 1 5 10 15 Tyr Phe Asp Ile 20 <210> 9560 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9560 Gly Gly Ser Ile Ser Ser Tyr Tyr 1 5 <210> 9561 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9561 Ile Tyr Tyr Ser Gly Ser Thr 1 5 <210> 9562 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9562 Ala Arg Gly Phe Asp Tyr 1 5 <210> 9563 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9563 Gly Gly Ser Phe Ser Gly Pro Tyr 1 5 <210> 9564 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9564 Ile Gly Pro Arg Gly Ile Thr 1 5 <210> 9565 <211> 15 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9565 Ala Arg Gly Leu Val Ile Gly Arg Ser Ser Leu Asn Phe Asp Ser 1 5 10 15 <210> 9566 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9566 Gly Phe Thr Phe Ser Gly Tyr Ala 1 5 <210> 9567 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9567 Ile Ser Gly Asn Asn Asn Asp Met 1 5 <210> 9568 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9568 Ala Arg Asp Asn Leu Ala Leu Ala Gly Glu Asp Tyr 1 5 10 <210> 9569 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9569 Gly Phe Thr Phe Ser Ser Tyr Ala 1 5 <210> 9570 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9570 Ile Ser Gly Gly Gly Glu Thr Thr 1 5 <210> 9571 <211> 17 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9571 Ala Lys Ser Pro Asp Ala Thr Phe Leu Trp Phe Gly Glu Pro Phe Gly 1 5 10 15 Tyr <210> 9572 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9572 Gly Phe Val Phe Ser Asp Tyr Ser 1 5 <210> 9573 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9573 Val Gly Val Asp Ala Val Thr Lys 1 5 <210> 9574 <211> 18 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9574 Ala Lys Ser Gln Pro Val Ser Arg Met Gly Arg Phe Phe Val Gly Leu 1 5 10 15 Asp Val <210> 9575 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9575 Gly Phe Thr Phe Ser Ser Tyr Ser 1 5 <210> 9576 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9576 Ile Ser Ser Thr Ser Ser Tyr Ile 1 5 <210> 9577 <211> 15 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9577 Ala Arg Arg Arg Ala Ala Thr Gly Thr Glu Phe Tyr Phe Asp Tyr 1 5 10 15 <210> 9578 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9578 Gly Gly Thr Phe Asn Ser His Ala 1 5 <210> 9579 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9579 Ile Val Pro Ile Arg Lys Thr Thr 1 5 <210> 9580 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9580 Ala Arg Val Ile Leu Ser Gly Arg Gly Phe Asp Ile 1 5 10 <210> 9581 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9581 Gly Gly Thr Phe Ser Ser Tyr Ala 1 5 <210> 9582 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9582 Ile Ile Leu Ile Leu Gly Ile Thr 1 5 <210> 9583 <211> 20 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9583 Ala Arg Glu Arg Pro Arg Asp Pro Ser Ser Asn Tyr Val Ala Tyr Tyr 1 5 10 15 Ala Met Asp Val 20 <210> 9584 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9584 Gly Gly Ser Ile Ser Ser Pro Asn Trp 1 5 <210> 9585 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9585 Val Tyr Pro Thr Gly Asn Thr 1 5 <210> 9586 <211> 17 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9586 Ala Arg Gly Val Val Gly Ala Ser Asp Phe Tyr Tyr Tyr Gly Met Asp 1 5 10 15 Val <210> 9587 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9587 Gly Leu Thr Ile Arg Asn Tyr Trp 1 5 <210> 9588 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9588 Met Glu Glu Asp Gly Ser Glu Lys 1 5 <210> 9589 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9589 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser 1 5 10 <210> 9590 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9590 Gly Gly Ser Phe Thr Asp Ser Tyr 1 5 <210> 9591 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9591 Val Asn His Ser Gly Ser Thr 1 5 <210> 9592 <211> 19 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9592 Ala Arg Gly Met Ala Val Arg Gly Arg Gln Leu Tyr Leu Leu Gly Gly 1 5 10 15 Tyr Asp Leu <210> 9593 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9593 Gly Asp Ser Ile Tyr Gly Tyr Tyr 1 5 <210> 9594 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9594 Val Tyr His Ser Gly Ser Thr 1 5 <210> 9595 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9595 Ala Arg Gly Leu Ala Gly Gly Gly Tyr Phe Asp Ala 1 5 10 <210> 9596 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9596 Gly Phe Pro Phe Gly Gly Tyr Gly 1 5 <210> 9597 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9597 Ile Asn Trp Ser Ala Asp Arg Arg 1 5 <210> 9598 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9598 Ala Arg Glu Arg Thr Ser Arg Arg Asp Phe Asp Phe 1 5 10 <210> 9599 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9599 Gly Phe Thr Phe Thr Ser Tyr Trp 1 5 <210> 9600 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9600 Ile Lys Gln Asp Gly Ser Glu Lys 1 5 <210> 9601 <211> 14 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9601 Ala Arg Asp Leu Gly Ser Gly Ser Tyr His Leu Phe Asp Tyr 1 5 10 <210> 9602 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9602 Gly Tyr Thr Phe Thr Ser Tyr Ala 1 5 <210> 9603 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9603 Ile Asn Ile Asn Thr Gly Asn Pro 1 5 <210> 9604 <211> 19 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9604 Ala Arg Asp Arg Gly Ile Ala Ala Arg Arg Gly Tyr Tyr Tyr Tyr Gly 1 5 10 15 Met Asp Val <210> 9605 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9605 Gly Phe Pro Phe Gly Gly Tyr Gly 1 5 <210> 9606 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9606 Ile Asn Trp Ser Ala Asp Arg Arg 1 5 <210> 9607 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9607 Ala Arg Glu Arg Thr Ser Arg Arg Asp Phe Asp Phe 1 5 10 <210> 9608 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9608 Gly Phe Thr Phe Thr Ser Tyr Trp 1 5 <210> 9609 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9609 Ile Lys Gln Asp Gly Ser Glu Lys 1 5 <210> 9610 <211> 14 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9610 Ala Arg Asp Leu Gly Ser Gly Ser Tyr His Leu Phe Asp Tyr 1 5 10 <210> 9611 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9611 Gly Gly Ser Ile Ser Ser Tyr Tyr 1 5 <210> 9612 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9612 Ile Tyr Tyr Ser Gly Ser Thr 1 5 <210> 9613 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9613 Ala Arg Gly Phe Asp Tyr 1 5 <210> 9614 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9614 Gly Tyr Asn Phe Thr Asn His Pro 1 5 <210> 9615 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9615 Ile Asn Thr Asn Thr Gly Asn Pro 1 5 <210> 9616 <211> 17 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9616 Val Arg Glu Asp Leu Arg Leu Arg Gln Val Trp Trp Arg Trp Phe Asp 1 5 10 15 Pro <210> 9617 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9617 Gly Phe Thr Phe Ser Ser Tyr Ala 1 5 <210> 9618 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9618 Ile Ser Tyr Asp Gly Ser Asn Lys 1 5 <210> 9619 <211> 14 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9619 Ala Arg Gly Lys Leu Gly Ile Val Gly Asp Ala Phe Asp Ile 1 5 10 <210> 9620 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9620 Gly Asp Ser Ile Tyr Gly Tyr Tyr 1 5 <210> 9621 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9621 Val Tyr His Ser Gly Ser Thr 1 5 <210> 9622 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9622 Ala Arg Gly Leu Ala Gly Gly Gly Tyr Phe Asp Ala 1 5 10 <210> 9623 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9623 Gly Asp Thr Phe Ser Thr Tyr Ala 1 5 <210> 9624 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9624 Ile Ile Pro Gly Leu Asp Leu Val 1 5 <210> 9625 <211> 20 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9625 Ala Arg Gly Arg Arg Tyr Asp Phe Leu Asp Gly Gln Tyr Thr Ser Trp 1 5 10 15 Tyr Phe Asp Ile 20 <210> 9626 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9626 Gly Tyr Thr Phe Thr Asp Tyr Tyr 1 5 <210> 9627 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9627 Val Asp Pro Glu Asp Gly Glu Thr 1 5 <210> 9628 <211> 15 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9628 Ala Thr Val Ser Arg Trp Tyr Tyr Tyr Tyr Tyr Gly Met Asp Val 1 5 10 15 <210> 9629 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9629 Gly Phe Asn Leu Ser Asn Tyr Ala 1 5 <210> 9630 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9630 Ile Ser Tyr Asp Gly Ser Ile Lys 1 5 <210> 9631 <211> 13 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9631 Val Arg Gly Gly Val Ser Gly Pro Asn Ser Phe Asp Met 1 5 10 <210> 9632 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9632 Gly Phe Val Phe Ser Asp Tyr Ser 1 5 <210> 9633 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9633 Val Gly Val Asp Ala Val Thr Lys 1 5 <210> 9634 <211> 18 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9634 Ala Lys Ser Gln Pro Val Ser Arg Met Gly Arg Phe Phe Val Gly Leu 1 5 10 15 Asp Val <210> 9635 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9635 Gly Phe Thr Phe Ile Ser Tyr Thr 1 5 <210> 9636 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9636 Ile Ser Tyr Asp Gly Tyr Asn Lys 1 5 <210> 9637 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9637 Ala Arg Glu Gly Ser Pro Glu Ala Phe Asp Tyr 1 5 10 <210> 9638 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9638 Gly Phe Thr Phe Ser Asp Tyr Tyr 1 5 <210> 9639 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9639 Ile Lys Pro Asp Gly Thr Gly Thr 1 5 <210> 9640 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9640 Val Ala Tyr Asn Trp Asn Tyr Asp Phe Cys 1 5 10 <210> 9641 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9641 Gly Phe Ser Tyr Ser Asn Tyr Trp 1 5 <210> 9642 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9642 Leu Arg Arg Asp Gly Ser Val Glu 1 5 <210> 9643 <211> 18 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9643 Ala Arg Asp Leu Ser Pro Gly Gly Leu Gly Ala Tyr Tyr Asp Val Phe 1 5 10 15 Asp Ile <210> 9644 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9644 Gly Phe Val Phe Ser Asp Tyr Ser 1 5 <210> 9645 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9645 Val Gly Val Asp Ala Val Thr Lys 1 5 <210> 9646 <211> 18 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9646 Ala Lys Ser Gln Pro Val Ser Arg Met Gly Arg Phe Phe Val Gly Leu 1 5 10 15 Asp Val <210> 9647 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9647 Gly Phe Thr Phe Ser Ser Tyr Ala 1 5 <210> 9648 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9648 Ile Ser Gly Ser Gly Gly Ser Thr 1 5 <210> 9649 <211> 15 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9649 Ala Lys Asp Gln His Met Val Arg Gly Ala Ile Gly Phe Asp Tyr 1 5 10 15 <210> 9650 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9650 Gly Phe Ile Phe Ser Asn Phe Trp 1 5 <210> 9651 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9651 Ile Gln Gln Asp Gly Ser Glu Lys 1 5 <210> 9652 <211> 13 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9652 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr 1 5 10 <210> 9653 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9653 Gly Phe Val Phe Ser Asp Tyr Ser 1 5 <210> 9654 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9654 Val Gly Val Asp Ala Val Thr Lys 1 5 <210> 9655 <211> 18 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9655 Ala Lys Ser Gln Pro Val Ser Arg Met Gly Arg Phe Phe Val Gly Leu 1 5 10 15 Asp Val <210> 9656 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9656 Gly Phe Thr Phe Ser Asn Tyr Ala 1 5 <210> 9657 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9657 Ile Ser Tyr Asp Gly Thr Ile Thr 1 5 <210> 9658 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9658 Gly Arg Asp Leu Ser Gly Gly Gly Leu Asp Val 1 5 10 <210> 9659 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9659 Gly Phe Thr Phe Ser Ile Tyr Ala 1 5 <210> 9660 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9660 Ile Ser Tyr Asp Gly Asn Asn Gln 1 5 <210> 9661 <211> 14 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9661 Ala Arg Ser Glu Gly Gly Gly Tyr His Asp Ala Phe Asp Ile 1 5 10 <210> 9662 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9662 Gly Phe Thr Phe Ile Ser Tyr Thr 1 5 <210> 9663 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9663 Ile Ser Tyr Asp Gly Tyr Asn Lys 1 5 <210> 9664 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9664 Ala Arg Glu Gly Ser Pro Glu Ala Phe Asp Tyr 1 5 10 <210> 9665 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9665 Gly Phe Thr Phe Ser Ser Tyr Ala 1 5 <210> 9666 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9666 Ile Ser Gly Gly Gly Glu Thr Thr 1 5 <210> 9667 <211> 17 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9667 Ala Lys Ser Pro Asp Ala Thr Phe Leu Trp Phe Gly Glu Pro Phe Gly 1 5 10 15 Tyr <210> 9668 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9668 Gly Asp Thr Phe Ser Thr Tyr Ala 1 5 <210> 9669 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9669 Ile Ile Pro Gly Leu Asp Leu Val 1 5 <210> 9670 <211> 20 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9670 Ala Arg Gly Arg Arg Tyr Asp Phe Leu Asp Gly Gln Tyr Thr Ser Trp 1 5 10 15 Tyr Phe Asp Ile 20 <210> 9671 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9671 Gly Phe Ile Phe Ser Asn Phe Trp 1 5 <210> 9672 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9672 Ile Gln Gln Asp Gly Ser Glu Lys 1 5 <210> 9673 <211> 13 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9673 Ala Arg Gln His Gly Asp Tyr Asp Trp Tyr Phe Asp Tyr 1 5 10 <210> 9674 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9674 Gly Leu Thr Ile Arg Asn Tyr Trp 1 5 <210> 9675 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9675 Met Glu Glu Asp Gly Ser Glu Lys 1 5 <210> 9676 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9676 Thr Arg Asp Pro Gly Pro Gly Asp Phe Ser 1 5 10 <210> 9677 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9677 Gln Asp Ile Asn Asn Tyr 1 5 <210> 9678 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9678 Ser Ala Ser 1 <210> 9679 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9679 Gln Gln Tyr Arg Ser Tyr Pro Arg Thr 1 5 <210> 9680 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9680 Ala Leu Pro Lys Gln Asn 1 5 <210> 9681 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9681 Lys Asp Ser 1 <210> 9682 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9682 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9683 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9683 Ala Leu Pro Lys Gln Asn 1 5 <210> 9684 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9684 Lys Asp Ser 1 <210> 9685 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9685 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9686 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9686 Gln Asp Ile Asn Asn Tyr 1 5 <210> 9687 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9687 Ser Ala Ser 1 <210> 9688 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9688 Gln Gln Tyr Arg Ser Tyr Pro Arg Thr 1 5 <210> 9689 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9689 Glu Ser Val Ser Ser Asn Tyr 1 5 <210> 9690 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9690 Asp Ala Ser 1 <210> 9691 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9691 Gln Gln Tyr Ala Arg Ala Pro Asp Thr 1 5 <210> 9692 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9692 Ser Gly Ser Val Ser Thr Ser Tyr Tyr 1 5 <210> 9693 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9693 Ser Thr Asn 1 <210> 9694 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9694 Val Leu Tyr Met Gly Ser Gly Ile Trp Val 1 5 10 <210> 9695 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9695 Ala Leu Pro Lys Gln Asn 1 5 <210> 9696 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9696 Lys Asp Ser 1 <210> 9697 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9697 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9698 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9698 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9699 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9699 Lys Asp Ser 1 <210> 9700 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9700 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9701 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9701 Gln Thr Val Asn Asn Asn 1 5 <210> 9702 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9702 Gly Thr Ser 1 <210> 9703 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9703 Gln Gln Tyr Tyr Glu Trp Pro Pro Ile Thr 1 5 10 <210> 9704 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9704 Gln Ser Leu Leu Tyr Ser Ser Asn Asn Arg Asp Tyr 1 5 10 <210> 9705 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9705 Trp Ala Ser 1 <210> 9706 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9706 Gln Gln Tyr Phe Ser Pro Pro Tyr Thr 1 5 <210> 9707 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9707 Gln Ser Val Thr Asn Tyr 1 5 <210> 9708 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9708 Gln Thr Ser 1 <210> 9709 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9709 Gln Gln Arg Ser His Arg Pro Gly Gly Ile Thr 1 5 10 <210> 9710 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9710 Gln Asp Ile Ser Asn Tyr 1 5 <210> 9711 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9711 Asp Ala Ser 1 <210> 9712 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9712 Gln Gln Tyr Asp Asn Leu Pro Leu Thr 1 5 <210> 9713 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9713 Gln Ser Leu Leu Tyr Ser Ser Asn Asn Arg Asp Tyr 1 5 10 <210> 9714 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9714 Trp Ala Ser 1 <210> 9715 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9715 Gln Gln Tyr Phe Ser Pro Pro Tyr Thr 1 5 <210> 9716 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9716 Gln Ser Leu Leu His Arg Asn Gly Tyr Asn Ile 1 5 10 <210> 9717 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9717 Leu Gly Ser 1 <210> 9718 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9718 Met Gln Gly Leu Gln Thr Pro Pro Tyr Thr 1 5 10 <210> 9719 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9719 Gln Ser Ile Thr Thr Tyr 1 5 <210> 9720 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9720 Ala Pro Ser 1 <210> 9721 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9721 Gln Gln Ser Tyr Ser Ser Pro Phe Thr 1 5 <210> 9722 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9722 Gln Thr Val Asn Asn Asn 1 5 <210> 9723 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9723 Gly Thr Ser 1 <210> 9724 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9724 Gln Gln Tyr Tyr Glu Trp Pro Pro Ile Thr 1 5 10 <210> 9725 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9725 Ala Leu Pro Lys Gln Asn 1 5 <210> 9726 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9726 Lys Asp Ser 1 <210> 9727 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9727 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9728 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9728 Gln Ser Val Ser Ser Ser Tyr 1 5 <210> 9729 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9729 Gly Thr Ser 1 <210> 9730 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9730 Gln Gln Tyr Gly Asn Ser Pro Trp Thr 1 5 <210> 9731 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9731 Gln Ser Val Ser Ser Tyr 1 5 <210> 9732 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9732 Asp Ala Ser 1 <210> 9733 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9733 Gln Gln Arg Ser Ser Trp Gln Gly Ile Thr 1 5 10 <210> 9734 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9734 Gln Ser Val Ser Ser Tyr 1 5 <210> 9735 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9735 Asp Ala Ser 1 <210> 9736 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9736 Gln Gln Arg Ser Ser Trp Gln Gly Ile Thr 1 5 10 <210> 9737 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9737 Gln Ser Val Ser Ser Tyr 1 5 <210> 9738 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9738 Asp Ala Ser 1 <210> 9739 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9739 Gln Gln Tyr Asn His Trp Arg Thr 1 5 <210> 9740 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9740 Gln Ser Leu Leu Tyr Ser Ser Asn Asn Arg Asp Tyr 1 5 10 <210> 9741 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9741 Trp Ala Ser 1 <210> 9742 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9742 Gln Gln Tyr Phe Ser Pro Pro Tyr Thr 1 5 <210> 9743 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9743 Glu Ser Val Ser Ser Asn Tyr 1 5 <210> 9744 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9744 Asp Ala Ser 1 <210> 9745 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9745 Gln Gln Tyr Ala Arg Ala Pro Asp Thr 1 5 <210> 9746 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9746 Gln Gly Leu Leu His Gly Asp Gly Lys Thr Tyr 1 5 10 <210> 9747 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9747 Glu Val Ser 1 <210> 9748 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9748 Met Gln Ser Val His Leu Pro Tyr Thr 1 5 <210> 9749 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9749 Lys Leu Gly Glu Lys Tyr 1 5 <210> 9750 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9750 Gln Asp Thr 1 <210> 9751 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9751 Gln Ala Trp Asp Tyr Thr Thr Val Ile 1 5 <210> 9752 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9752 Gln Ser Val Ser Ser Ser Tyr 1 5 <210> 9753 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9753 Gly Ala Ser 1 <210> 9754 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9754 Gln Gln Tyr Gly Ser Ser Tyr Thr 1 5 <210> 9755 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9755 Gln Ser Val Ser Ser Tyr 1 5 <210> 9756 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9756 Asp Ala Ser 1 <210> 9757 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9757 Gln Gln Tyr Arg Ser Tyr Pro Arg Thr 1 5 <210> 9758 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9758 Gln Ser Ile Thr Thr Tyr 1 5 <210> 9759 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9759 Ala Pro Ser 1 <210> 9760 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9760 Gln Gln Ser Tyr Ser Ser Pro Phe Thr 1 5 <210> 9761 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9761 Gln Ser Leu Leu Tyr Gly Asn Gly Tyr Asn Tyr 1 5 10 <210> 9762 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9762 Leu Gly Ser 1 <210> 9763 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9763 Met Gln Gly Gln Glu Asn Pro Pro Thr 1 5 <210> 9764 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9764 Gln Ser Val Ser Ser Asn 1 5 <210> 9765 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9765 Gly Ala Ser 1 <210> 9766 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9766 Gln Gln Tyr Asn Asn Trp Arg Thr 1 5 <210> 9767 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9767 Ser Val Leu Tyr Ser Ser Ile Asn Lys Asn Tyr 1 5 10 <210> 9768 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9768 Trp Ala Ser 1 <210> 9769 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9769 Gln Gln Tyr Tyr Ser Thr Pro Tyr Thr 1 5 <210> 9770 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9770 Ser Ser Asn Ile Gly Ser Asn Tyr 1 5 <210> 9771 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9771 Arg Asn Tyr 1 <210> 9772 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9772 Ala Val Trp Asp Asp Ser Leu Ser Gly Trp Val 1 5 10 <210> 9773 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9773 Gln Thr Val Asn Asn Asn 1 5 <210> 9774 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9774 Gly Thr Ser 1 <210> 9775 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9775 Gln Gln Tyr Tyr Glu Trp Pro Pro Ile Thr 1 5 10 <210> 9776 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9776 Arg Ser Leu Leu Ser Arg Asn Gly Tyr Asn Tyr 1 5 10 <210> 9777 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9777 Leu Gly Ser 1 <210> 9778 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9778 Met Gln Ala Met Gln Ala Pro Leu Thr 1 5 <210> 9779 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9779 Ala Leu Pro Lys Gln Asn 1 5 <210> 9780 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9780 Lys Asp Ser 1 <210> 9781 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9781 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9782 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9782 Ala Leu Pro Lys Gln Asn 1 5 <210> 9783 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9783 Lys Asp Ser 1 <210> 9784 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9784 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9785 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9785 Ala Leu Pro Lys Gln Asn 1 5 <210> 9786 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9786 Lys Asp Ser 1 <210> 9787 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9787 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9788 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9788 Glu Ser Val Ser Ser Asn Tyr 1 5 <210> 9789 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9789 Asp Ala Ser 1 <210> 9790 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9790 Gln Gln Tyr Ala Arg Ala Pro Asp Thr 1 5 <210> 9791 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9791 Gln Ser Leu Leu Tyr Ser Ser Asn Asn Arg Asp Tyr 1 5 10 <210> 9792 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9792 Trp Ala Ser 1 <210> 9793 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9793 Gln Gln Tyr Phe Ser Pro Pro Tyr Thr 1 5 <210> 9794 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9794 Gln Ser Val Ser Ser Asn 1 5 <210> 9795 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9795 Gly Ala Ser 1 <210> 9796 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9796 Gln Gln Tyr Asn Asn Trp Arg Phe Thr 1 5 <210> 9797 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9797 Gln Ser Leu Leu Tyr Ser Ser Asn Asn Arg Asp Tyr 1 5 10 <210> 9798 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9798 Trp Ala Ser 1 <210> 9799 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9799 Gln Gln Tyr Phe Ser Pro Pro Tyr Thr 1 5 <210> 9800 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9800 Ser Ser Asn Ile Gly Asn Asn Tyr 1 5 <210> 9801 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9801 Asp Asn Asn 1 <210> 9802 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9802 Gly Thr Trp Asp Ser Ser Leu Ser Ala Val Leu 1 5 10 <210> 9803 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9803 His Asp Ile Gly His Asn 1 5 <210> 9804 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9804 Asp Val Ser 1 <210> 9805 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9805 Gln Gln Tyr Asp Ser Ile 1 5 <210> 9806 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9806 Gln Ser Ile Thr Thr Tyr 1 5 <210> 9807 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9807 Ala Pro Ser 1 <210> 9808 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9808 Gln Gln Ser Tyr Ser Ser Pro Phe Thr 1 5 <210> 9809 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9809 Glu Thr Ile Ser Asn Phe 1 5 <210> 9810 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9810 Ser Ala Ala 1 <210> 9811 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9811 Gln Gln Ser Phe Asn Thr Pro Arg Thr 1 5 <210> 9812 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9812 Glu Ser Val Ser Ser Asn Tyr 1 5 <210> 9813 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9813 Asp Ala Ser 1 <210> 9814 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9814 Gln Gln Tyr Ala Arg Ala Pro Asp Thr 1 5 <210> 9815 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9815 Gln Ser Val Tyr Ile Asn 1 5 <210> 9816 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9816 Gly Ala Ser 1 <210> 9817 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9817 Gln Gln Tyr Asn His Trp Arg Thr 1 5 <210> 9818 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9818 Pro Gly Ile Asn Thr Tyr 1 5 <210> 9819 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9819 Gly Ala Ser 1 <210> 9820 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9820 Gln Ala Tyr Tyr Val Gly Leu Gly Thr 1 5 <210> 9821 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9821 Tyr Arg Gly Ser Gln Thr 1 5 <210> 9822 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9822 Ser Asp Asp 1 <210> 9823 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9823 Gln Val Trp Asp Pro Ser Ser Asp Gln Ala Leu 1 5 10 <210> 9824 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9824 Ala Leu Pro Lys Gln Asn 1 5 <210> 9825 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9825 Lys Asp Ser 1 <210> 9826 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9826 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9827 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9827 Gln Ser Ile Thr Thr Tyr 1 5 <210> 9828 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9828 Ala Pro Ser 1 <210> 9829 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9829 Gln Gln Ser Tyr Ser Ser Pro Phe Thr 1 5 <210> 9830 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9830 Ala Leu Pro Lys Gln Asn 1 5 <210> 9831 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9831 Lys Asp Ser 1 <210> 9832 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9832 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9833 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9833 Ser Ser Asn Ile Gly Asn Asn Tyr 1 5 <210> 9834 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9834 Asp Asn Asn 1 <210> 9835 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9835 Gly Thr Trp Asp Asn Ser Leu Ser Ala Trp Val 1 5 10 <210> 9836 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9836 Gln Ser Val Ser Ser Tyr 1 5 <210> 9837 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9837 Asp Ala Ser 1 <210> 9838 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9838 Gln Gln Arg Ser Ser Trp Gln Gly Ile Thr 1 5 10 <210> 9839 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9839 Gln Ser Val Gly Gly His 1 5 <210> 9840 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9840 Ala Ala Ser 1 <210> 9841 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9841 Gln Gln Ser Arg Asn Ser Pro Ala Thr 1 5 <210> 9842 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9842 Gln Asp Ile Ser Asn Tyr 1 5 <210> 9843 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9843 Asp Ala Ser 1 <210> 9844 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9844 Gln Gln Tyr Asp Asn Leu Pro Leu Thr 1 5 <210> 9845 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9845 Ala Leu Pro Lys Gln Asn 1 5 <210> 9846 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9846 Lys Asp Ser 1 <210> 9847 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9847 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9848 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9848 Gln Thr Val Asn Asn Asn 1 5 <210> 9849 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9849 Gly Thr Ser 1 <210> 9850 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9850 Gln Gln Tyr Tyr Glu Trp Pro Pro Ile Thr 1 5 10 <210> 9851 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9851 Gln Ser Val Ser Ser Ser Tyr 1 5 <210> 9852 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9852 Gly Ala Ser 1 <210> 9853 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9853 Gln Gln Tyr Gly Ser Ser Tyr Thr 1 5 <210> 9854 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9854 Gln Ser Leu Val Tyr Ser Asp Gly Asn Thr Tyr 1 5 10 <210> 9855 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9855 Gln Val Ser 1 <210> 9856 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9856 Met Gln Gly Thr His Trp Pro Val Thr 1 5 <210> 9857 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9857 Ser Asn Asp Val Gly Arg Tyr Asn Tyr 1 5 <210> 9858 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9858 Glu Val Val 1 <210> 9859 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9859 Ser Ser Tyr Gly Gly Asn Asn Ile Leu Leu 1 5 10 <210> 9860 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9860 Ala Leu Pro Lys Gln Asn 1 5 <210> 9861 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9861 Lys Asp Ser 1 <210> 9862 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9862 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9863 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9863 Gln Ser Leu Val Tyr Ser Asp Gly Asn Thr Tyr 1 5 10 <210> 9864 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9864 Gln Val Ser 1 <210> 9865 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9865 Met Gln Gly Ser Tyr Trp Pro Phe Thr 1 5 <210> 9866 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9866 Gln Gly Ile Gly Asn Glu 1 5 <210> 9867 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9867 Ala Gly Ser 1 <210> 9868 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9868 Leu Gln Asp Tyr Ala Tyr Pro Arg Thr 1 5 <210> 9869 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9869 Gln Ser Val Ser Ser Ser Tyr 1 5 <210> 9870 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9870 Gly Ala Ser 1 <210> 9871 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9871 Gln Gln Tyr Gly Ser Ser Tyr Thr 1 5 <210> 9872 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9872 Gln Ser Val Ser Ser Asn 1 5 <210> 9873 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9873 Gly Ala Ser 1 <210> 9874 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9874 Gln Gln Tyr Asn Asn Trp Arg Thr 1 5 <210> 9875 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9875 Gln Gly Ile Asn Ser Trp 1 5 <210> 9876 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9876 Ala Ala Ser 1 <210> 9877 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9877 Gln Gln Ala His Ser Phe Pro Ile Thr 1 5 <210> 9878 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9878 Ala Leu Pro Lys Gln Asn 1 5 <210> 9879 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9879 Lys Asp Ser 1 <210> 9880 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9880 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10 <210> 9881 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9881 Ser Asn Asp Val Gly Gly His Asn Tyr 1 5 <210> 9882 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9882 Asp Val Thr 1 <210> 9883 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9883 Cys Ser Tyr Lys Ser Thr Tyr Asp Tyr Val 1 5 10 <210> 9884 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9884 Ser Gly His Ser Ser Tyr Ala 1 5 <210> 9885 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9885 Leu Asn Ser Asp Gly Ser His 1 5 <210> 9886 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9886 Gln Thr Trp Gly Thr Gly Ile His Val 1 5 <210> 9887 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9887 Ala Leu Ser Lys Gln Phe 1 5 <210> 9888 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9888 Lys Asp Ser 1 <210> 9889 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9889 Gln Ser Ala His Ser Ser Gly Phe Tyr Arg Val Val 1 5 10 <210> 9890 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9890 Gln Thr Val Asn Asn Asn 1 5 <210> 9891 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9891 Gly Thr Ser 1 <210> 9892 <211> 10 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9892 Gln Gln Tyr Tyr Glu Trp Pro Pro Ile Thr 1 5 10 <210> 9893 <211> 12 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9893 Gln Ser Leu Leu Tyr Ser Ser Asn Asn Arg Asp Tyr 1 5 10 <210> 9894 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9894 Trp Ala Ser 1 <210> 9895 <211> 9 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9895 Gln Gln Tyr Phe Ser Pro Pro Tyr Thr 1 5 <210> 9896 <211> 7 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9896 Gln Ser Val Ser Ser Ser Tyr 1 5 <210> 9897 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9897 Gly Ala Ser 1 <210> 9898 <211> 8 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9898 Gln Gln Tyr Gly Ser Ser Tyr Thr 1 5 <210> 9899 <211> 6 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9899 Ala Leu Pro Lys Gln Asn 1 5 <210> 9900 <211> 3 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9900 Lys Asp Ser 1 <210> 9901 <211> 11 <212> PRT <213> Artificial sequence <220> <223> Synthetic antibody <400> 9901 Gln Ser Ala Asp Ser Ser Gly Thr Tyr Val Val 1 5 10

Claims (97)

  1. 대상체(subject)에서 SARS-CoV-2에 의한 COVID-19 감염을 검출하는 방법으로서,
    (a) 상기 대상체로부터의 샘플을 각각 표 3 및 표 4로부터의 클론-쌍(clone-paired) 중쇄 및 경쇄 CDR 서열을 갖는 항체 또는 항체 단편과 접촉시키는 단계; 및
    (b) 상기 샘플에서 상기 항체 또는 항체 단편을 SARS-CoV-2 항원에 결합시킴으로써 상기 샘플에서 SARS-CoV-2를 검출하는 단계를 포함하는, 방법.
  2. 제1항에 있어서, 상기 샘플은 체액인, 방법.
  3. 제1항 또는 제2항에 있어서, 상기 샘플은 혈액, 가래, 눈물, 타액, 점액 또는 혈청, 정액, 자궁경부 또는 질 분비물, 양수, 태반 조직, 소변, 삼출물, 여출물(transudate), 찰과표본(tissue scraping) 또는 분변인, 방법.
  4. 제1항 내지 제3항 중 어느 한 항에 있어서, 검출은 ELISA, RIA, 측방 유동 분석(lateral flow assay) 또는 웨스턴 블롯(western blot)을 포함하는, 방법.
  5. 제1항 내지 제4항 중 어느 한 항에 있어서, 단계 (a) 및 (b)를 두 번째로 수행하고 제1 분석과 비교하여 SARS-CoV-2 항원 수준의 변화를 결정하는 단계를 추가로 포함하는, 방법.
  6. 제1항 내지 제5항 중 어느 한 항에 있어서, 항체 또는 항체 단편은 표 1에 제시된 바와 같은 클론-쌍 가변 서열에 의해 인코딩(encoding)되는, 방법.
  7. 제1항 내지 제5항 중 어느 한 항에 있어서, 상기 항체 또는 항체 단편은 표 1에 제시된 바와 같은 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성(identity)을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 방법.
  8. 제1항 내지 제5항 중 어느 한 항에 있어서, 상기 항체 또는 항체 단편은 표 1에 제시된 바와 같은 클론-쌍 서열에 대해 100% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 방법.
  9. 제1항 내지 제5항 중 어느 한 항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  10. 제1항 내지 제5항 중 어느 한 항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  11. 제1항 내지 제10항 중 어느 한 항에 있어서, 상기 항체 또는 항체 단편은 SARS-CoV-2 표면 스파이크 단백질(surface spike protein)에 결합하는, 방법.
  12. 제1항 내지 제11항 중 어느 한 항에 있어서, 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편인, 방법.
  13. SARS-CoV-2에 감염된 대상체를 치료하거나 SARS-CoV-2에 감염될 위험이 있는 대상체의 감염 가능성을 감소시키는 방법으로서, 상기 대상체에게 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 갖는 항체 또는 항체 단편을 전달하는 단계를 포함하는, 방법.
  14. 제13항에 있어서, 항체 또는 항체 단편은 표 1에 제시된 바와 같은 클론-쌍 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 방법.
  15. 제13항 또는 제14항에 있어서, 상기 항체 또는 항체 단편은 표 1로부터의 클론-쌍 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 방법.
  16. 제13항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  17. 제13항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 대해 적어도 70%, 80% 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  18. 제13항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  19. 제13항 내지 제18항 중 어느 한 항에 있어서, 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편인, 방법.
  20. 제13항 내지 제19항 중 어느 한 항에 있어서, 상기 항체는 LALA, LALA PG, N297, GASD/ALIE, DHS, YTE 또는 LS 돌연변이와 같은, 반감기를 증가시키고/거나 치료적 효능을 증가시키기 위해, Fc 상호작용을 변경(제거 또는 향상)하도록 돌연변이된 Fc 부분, 또는 글리칸의 효소적 또는 화학적 첨가 또는 제거 또는 정해진 글리코실화 패턴으로 조작된 세포주에서의 발현과 같은 FcR 상호작용을 변경(제거 또는 향상)하도록 변형된 글리칸을 포함하는 IgG, 또는 재조합 IgG 항체 또는 항체 단편인, 방법.
  21. 제13항 내지 제18항 중 어느 한 항에 있어서, 상기 항체는 키메라 항체(chimeric antibody) 또는 이중특이적 항체(bispecific antibody)인, 방법.
  22. 제13항 내지 제21항 중 어느 한 항에 있어서, 상기 항체 또는 항체 단편은 SARS-CoV-2 표면 스파이크 단백질에 결합하는, 방법.
  23. 제13항 내지 제22항 중 어느 한 항에 있어서, 상기 항체 또는 항체 단편은 감염 전 또는 감염 후에 투여되는, 방법.
  24. 제13항 내지 제23항 중 어느 한 항에 있어서, 상기 대상체는 60세 이상이거나, 면역이 저하되었거나, 호흡기 및/또는 심혈관 장애를 앓고 있는, 방법.
  25. 제13항 내지 제24항 중 어느 한 항에 있어서, 전달은 항체 또는 항체 단편 투여, 또는 항체 또는 항체 단편을 인코딩하는 RNA 또는 DNA 서열, 또는 벡터를 사용한 유전자 전달을 포함하는, 방법.
  26. 단일클론 항체(monoclonal antibody)로서, 여기서 항체 또는 항체 단편은 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 특징으로 하는, 단일클론 항체.
  27. 제26항에 있어서, 상기 항체 또는 항체 단편은 표 1로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 단일클론 항체.
  28. 제26항에 있어서, 상기 항체 또는 항체 단편은 표 1로부터의 클론-쌍 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 단일클론 항체.
  29. 제26항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열을 포함하는, 단일클론 항체.
  30. 제26항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함하는, 단일클론 항체.
  31. 제26항 내지 제30항 중 어느 한 항에 있어서, 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편인, 단일클론 항체.
  32. 제26항 내지 제30항 중 어느 한 항에 있어서, 상기 항체는 키메라 항체이거나, 이중특이적 항체인, 단일클론 항체.
  33. 제26항 내지 제32항 중 어느 한 항에 있어서, 상기 항체는 LALA, LALA PG, N297, GASD/ALIE, DHS, YTE 또는 LS 돌연변이와 같은, 반감기를 증가시키고/거나 치료적 효능을 증가시키기 위해, Fc 상호작용을 변경(제거 또는 향상)하도록 돌연변이된 Fc 부분, 또는 글리칸의 효소적 또는 화학적 첨가 또는 제거 또는 정해진 글리코실화 패턴으로 조작된 세포주에서의 발현과 같은 FcR 상호작용을 변경(제거 또는 향상)하도록 변형된 글리칸을 포함하는 IgG, 또는 재조합 IgG 항체 또는 항체 단편인, 단일클론 항체.
  34. 제26항 내지 제33항 중 어느 한 항에 있어서, 상기 항체 또는 항체 단편은 SARS-CoV-2 항원, 예컨대 표면 스파이크 단백질에 결합하는, 단일클론 항체.
  35. 제26항 내지 제34항 중 어느 한 항에 있어서, 상기 항체는 인트라바디(intrabody)인, 단일클론 항체.
  36. 항체 또는 항체 단편을 인코딩하는 하이브리도마(hybridoma) 또는 조작된 세포로서, 여기서 항체 또는 항체 단편은 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 특징으로 하는, 하이브리도마 또는 조작된 세포.
  37. 제36항에 있어서, 상기 항체 또는 항체 단편은 표 1로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 하이브리도마 또는 조작된 세포.
  38. 제36항에 있어서, 상기 항체 또는 항체 단편은 표 1로부터의 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 하이브리도마 또는 조작된 세포.
  39. 제36항에 있어서, 상기 항체 또는 항체 단편은 표 1로부터의 클론-쌍 가변 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 하이브리도마 또는 조작된 세포.
  40. 제36항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열을 포함하는, 하이브리도마 또는 조작된 세포.
  41. 제36항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 하이브리도마 또는 조작된 세포.
  42. 제36항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함하는, 하이브리도마 또는 조작된 세포.
  43. 제36항 내지 제42항 중 어느 한 항에 있어서, 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편인, 하이브리도마 또는 조작된 세포.
  44. 제36항 내지 제43항 중 어느 한 항에 있어서, 상기 항체는 키메라 항체, 이중특이적 항체, 또는 인트라바디(intrabody)인, 하이브리도마 또는 조작된 세포.
  45. 제36항 내지 제43항 중 어느 한 항에 있어서, 상기 항체는 LALA, LALA PG, N297, GASD/ALIE, DHS, YTE 또는 LS 돌연변이와 같은, 반감기를 증가시키고/거나 치료적 효능을 증가시키기 위해, Fc 상호작용을 변경(제거 또는 향상)하도록 돌연변이된 Fc 부분, 또는 글리칸의 효소적 또는 화학적 첨가 또는 제거 또는 정해진 글리코실화 패턴으로 조작된 세포주에서의 발현과 같은 FcR 상호작용을 변경(제거 또는 향상)하도록 변형된 글리칸을 포함하는 IgG, 또는 재조합 IgG 항체 또는 항체 단편인, 하이브리도마 또는 조작된 세포.
  46. 제36항 내지 제45항 중 어느 한 항에 있어서, 상기 항체 또는 항체 단편은 SARS-CoV-2 표면 스파이크 단백질에 결합하는, 하이브리도마 또는 조작된 세포.
  47. 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 특징으로 하는 하나 이상의 항체 또는 항체 단편을 포함하는 백신 제형.
  48. 제47항에 있어서, 적어도 하나의 상기 항체 또는 항체 단편은 표 1로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 백신 제형.
  49. 제47항에 있어서, 적어도 하나의 상기 항체 또는 항체 단편은 표 1로부터의 클론-쌍 서열에 대해 적어도 70%, 80%, 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 백신 제형.
  50. 제47항에 있어서, 적어도 하나의 상기 항체 또는 항체 단편은 표 1로부터의 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 백신 제형.
  51. 제47항에 있어서, 적어도 하나의 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열을 포함하는, 백신 제형.
  52. 제47항에 있어서, 적어도 하나의 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 대해 적어도 70%, 80%, 90% 또는 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함하는, 백신 제형.
  53. 제47항 내지 제52항 중 어느 한 항에 있어서, 적어도 하나의 상기 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편인, 백신 제형.
  54. 제47항 내지 제52항 중 어느 한 항에 있어서, 적어도 하나의 상기 항체는 키메라 항체는 이중특이적 항체 또는 인트라바디인, 백신 제형.
  55. 제47항 내지 제54항 중 어느 한 항에 있어서, 상기 항체는 LALA, LALA PG, N297, GASD/ALIE, DHS YTE 또는 LS 돌연변이와 같은, 반감기를 증가시키고/거나 치료적 효능을 증가시키기 위해, Fc 상호작용을 변경(제거 또는 향상)하도록 돌연변이된 Fc 부분, 또는 글리칸의 효소적 또는 화학적 첨가 또는 제거 또는 정해진 글리코실화 패턴으로 조작된 세포주에서의 발현과 같은 FcR 상호작용을 변경(제거 또는 향상)하도록 변형된 글리칸을 포함하는 IgG, 또는 재조합 IgG 항체 또는 항체 단편인, 백신 제형.
  56. 제47항 내지 제55항 중 어느 한 항에 있어서, 상기 항체 또는 항체 단편은 SARS-CoV-2 표면 스파이크 단백질에 결합하는, 백신 제형.
  57. 제26항 내지 제34항 중 어느 한 항에 따른 1차 항체 또는 항체 단편을 인코딩하는 하나 이상의 발현 벡터를 포함하는 백신 제형.
  58. 제57항에 있어서, 상기 발현 벡터(들)는 신드비스 바이러스(Sindbis virus) 또는 VEE 벡터(들)인, 백신 제형.
  59. 제57항 내지 제58항 중 어느 한 항에 있어서, 바늘 주입, 제트 주입(jet injection) 또는 전기천공에 의한 전달을 위해 제형화되는, 백신 제형.
  60. 제57항에 있어서, 제26항 내지 제34항 중 어느 한 항의 별도의 항체 또는 항체 단편과 같은, 2차 항체 또는 항체 단편을 인코딩하는 하나 이상의 발현 벡터를 추가로 포함하는, 백신 제형.
  61. 60세 이상의 대상체, 면역이 저하된 대상체 또는 SARS-CoV-2에 감염되었거나 감염될 위험이 있는 호흡기 및/또는 심혈관 장애를 앓고 있는 대상체의 건강을 보호하는 방법으로서, 상기 대상체에게 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 갖는 항체 또는 항체 단편을 전달하는 단계를 포함하는, 방법.
  62. 제61항에 있어서, 항체 또는 항체 단편은 표 1에 제시된 바와 같은 클론-쌍 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 방법.
  63. 제61항 또는 제62항에 있어서, 항체 또는 항체 단편은 표 1에 제시된 것에 대해 적어도 95% 동일성을 갖는 클론-쌍 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 방법.
  64. 제61항 또는 제62항에 있어서, 상기 항체 또는 항체 단편은 표 1로부터의 클론-쌍 서열에 대해 적어도 70%, 80%, 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 방법.
  65. 제61항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  66. 제61항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 대해 적어도 70%, 80% 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  67. 제61항에 있어서, 상기 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  68. 제61항 내지 제67항 중 어느 한 항에 있어서, 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편인, 방법.
  69. 제61항 내지 제68항 중 어느 한 항에 있어서, 상기 항체는 LALA, LALA PG, N297, GASD/ALIE, DHS, YTE 또는 LS 돌연변이와 같은, 반감기를 증가시키고/거나 치료적 효능을 증가시키기 위해, Fc 상호작용을 변경(제거 또는 향상)하도록 돌연변이된 Fc 부분, 또는 글리칸의 효소적 또는 화학적 첨가 또는 제거 또는 정해진 글리코실화 패턴으로 조작된 세포주에서의 발현과 같은 FcR 상호작용을 변경(제거 또는 향상)하도록 변형된 글리칸을 포함하는 IgG, 또는 재조합 IgG 항체 또는 항체 단편인, 방법.
  70. 제61항 내지 제67항 중 어느 한 항에 있어서, 상기 항체는 키메라 항체(bispecific antibody) 또는 이중특이적 항체인, 방법.
  71. 제61항 내지 제70항 중 어느 한 항에 있어서, 상기 항체 또는 항체 단편은 감염 전 또는 감염 후에 투여되는, 방법.
  72. 제61항 내지 제71항 중 어느 한 항에 있어서, 상기 항체 또는 항체 단편은 SARS-CoV-2 표면 스파이크 단백질에 결합하는, 방법.
  73. 제61항 내지 제72항 중 어느 한 항에 있어서, 전달은 항체 또는 항체 단편 투여, 또는 항체 또는 항체 단편을 인코딩하는 RNA 또는 DNA 서열, 또는 벡터를 사용한 유전자 전달을 포함하는, 방법.
  74. 제61항에 있어서, 항체 또는 항체 단편은 비처리 대조군과 비교하여 대상체의 호흡을 개선하는, 방법.
  75. 제61항에 있어서, 항체 또는 항체 단편은 비처리 대조군과 비교하여 바이러스 함량을 감소시키는, 방법.
  76. SARS-CoV-2 표면 스파이크 단백질의 항원 완전성(antigenic integrity), 정확한 입체형태(conformation) 및/또는 정확한 서열을 결정하는 방법으로서,
    (a) 상기 항원을 포함하는 샘플을 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 갖는 1차 항체 또는 항체 단편과 접촉시키는 단계; 및
    (b) 상기 항원에 대한 상기 1차 항체 또는 항체 단편의 검출가능한 결합에 의해 상기 항원의 항원 완전성, 정확한 입체형태 및/또는 정확한 서열을 결정하는 단계를 포함하는, 방법.
  77. 제76항에 있어서, 상기 샘플은 재조합에 의해 생산된 항원을 포함하는, 방법.
  78. 제76항에 있어서, 상기 샘플은 백신 제형 또는 백신 생산 뱃치(production batch)를 포함하는, 방법.
  79. 제76항 내지 제78항 중 어느 한 항에 있어서, 검출은 ELISA, RIA, 웨스턴 블롯, 표면 플라즈몬 공명 또는 생물층 간섭계를 사용하는 바이오센서, 또는 유세포 분석 염색(flow cytometric staining)을 포함하는, 방법.
  80. 제76항 내지 제79항 중 어느 한 항에 있어서, 1차 항체 또는 항체 단편은 표 1에 제시된 클론-쌍 가변 서열에 의해 인코딩되는, 방법.
  81. 제76항 내지 제79항 중 어느 한 항에 있어서, 상기 1차 항체 또는 항체 단편은 표 1에 제시된 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 방법.
  82. 제76항 내지 제79항 중 어느 한 항에 있어서, 상기 1차 항체 또는 항체 단편은 표 1에 제시된 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 방법.
  83. 제76항 내지 제79항 중 어느 한 항에 있어서, 상기 1차 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  84. 제76항 내지 제79항 중 어느 한 항에 있어서, 상기 1차 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 대해 적어도 70%, 80% 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  85. 제76항 내지 제79항 중 어느 한 항에 있어서, 상기 1차 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  86. 제76항 내지 제85항 중 어느 한 항에 있어서, 1차 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편인, 방법.
  87. 제76항 내지 제86항 중 어느 한 항에 있어서, 시간 경과에 따른 항원의 항원 안정성을 결정하기 위해 단계 (a) 및 (b)를 두 번째로 수행하는 단계를 추가로 포함하는, 방법.
  88. 제76항 내지 제87항 중 어느 한 항에 있어서,
    (c) 상기 항원을 포함하는 샘플을 각각 표 3 및 표 4로부터의 클론-쌍 중쇄 및 경쇄 CDR 서열을 갖는 2차 항체 또는 항체 단편과 접촉시키는 단계; 및
    (d) 상기 항원에 대한 상기 2차 항체 또는 항체 단편의 검출가능한 결합에 의해 상기 항원의 항원 완전성을 결정하는 단계
    를 추가로 포함하는, 방법.
  89. 제88항에 있어서, 2차 항체 또는 항체 단편은 표 1에 제시된 클론-쌍 가변 서열에 의해 인코딩되는, 방법.
  90. 제89항에 있어서, 상기 2차 항체 또는 항체 단편은 표 1에 제시된 클론-쌍 가변 서열에 대해 적어도 70%, 80%, 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 방법.
  91. 제89항에 있어서, 상기 2차 항체 또는 항체 단편은 표 1에 제시된 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열에 의해 인코딩되는, 방법.
  92. 제89항에 있어서, 상기 2차 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 따른 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  93. 제89항에 있어서, 상기 2차 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 대해 적어도 70%, 80% 또는 90% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  94. 제89항에 있어서, 상기 2차 항체 또는 항체 단편은 표 2로부터의 클론-쌍 서열에 대해 적어도 95% 동일성을 갖는 경쇄 및 중쇄 가변 서열을 포함하는, 방법.
  95. 제89항에 있어서, 2차 항체 단편은 재조합 scFv (단일 사슬 가변 단편) 항체, Fab 단편, F(ab')2 단편, 또는 Fv 단편인, 방법.
  96. 제89항에 있어서, 시간 경과에 따른 항원의 항원 안정성을 결정하기 위해 단계 (c) 및 (d)를 두 번째로 수행하는 단계를 추가로 포함하는, 방법.
  97. 인간 단일클론 항체 또는 항체 단편, 또는 하이브리도마 또는 이를 생산하는 조작된 세포로서, 상기 항체는 SARS-CoV-2 표면 스파이크 단백질에 결합하는, 인간 단일클론 항체 또는 항체 단편, 또는 하이브리도마 또는 이를 생산하는 조작된 세포.
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