AR103782A1 - ANTAGONISTAS DE INTEGRINA b7 Y MÉTODOS DE TRATAMIENTO DE LA ENFERMEDAD DE CROHN - Google Patents
ANTAGONISTAS DE INTEGRINA b7 Y MÉTODOS DE TRATAMIENTO DE LA ENFERMEDAD DE CROHNInfo
- Publication number
- AR103782A1 AR103782A1 ARP160100498A ARP160100498A AR103782A1 AR 103782 A1 AR103782 A1 AR 103782A1 AR P160100498 A ARP160100498 A AR P160100498A AR P160100498 A ARP160100498 A AR P160100498A AR 103782 A1 AR103782 A1 AR 103782A1
- Authority
- AR
- Argentina
- Prior art keywords
- methods
- antagonists
- disease
- integrin
- crohn
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Transplantation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se proporcionan métodos de tratamiento de trastornos inflamatorios gastrointestinales tales como enfermedades intestinales inflamatorias que incluyen enfermedad de Crohn. También se proporcionan métodos de administración y dosificación de antagonistas de integrina b7, tales como anticuerpos anti-integrina b7. Además, se proporcionan métodos de administración y dosificación de tales antagonistas de integrina b7 para inducir la remisión o para inducir remisión y mantener la remisión de la enfermedad de Crohn. Reivindicación 2: El método de acuerdo con la reivindicación 1, en donde el antagonista de integrina b7 es un anticuerpo monoclonal de anti-integrina b7.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562121290P | 2015-02-26 | 2015-02-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR103782A1 true AR103782A1 (es) | 2017-05-31 |
Family
ID=55487172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP160100498A AR103782A1 (es) | 2015-02-26 | 2016-02-25 | ANTAGONISTAS DE INTEGRINA b7 Y MÉTODOS DE TRATAMIENTO DE LA ENFERMEDAD DE CROHN |
Country Status (12)
Country | Link |
---|---|
US (3) | US20180086833A1 (es) |
EP (2) | EP3978530A1 (es) |
JP (2) | JP2018507868A (es) |
KR (1) | KR20170120601A (es) |
CN (2) | CN107257693A (es) |
AR (1) | AR103782A1 (es) |
AU (2) | AU2016222683A1 (es) |
CA (1) | CA2972099A1 (es) |
HK (1) | HK1244229A1 (es) |
IL (1) | IL253130B2 (es) |
MX (1) | MX2017010336A (es) |
WO (1) | WO2016138207A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012154987A1 (en) | 2011-05-10 | 2012-11-15 | Nestec Sa | Methods of disease activity profiling for personalized therapy management |
WO2018111322A1 (en) * | 2016-12-14 | 2018-06-21 | Progenity Inc. | Methods and ingestible devices for the regio-specific release of integrin inhibitors at the site of gastrointestinal tract disease |
MX2019012749A (es) * | 2017-04-28 | 2020-02-03 | Millennium Pharm Inc | Metodos para tratar trastornos pediatricos. |
US11162943B2 (en) | 2017-05-31 | 2021-11-02 | Prometheus Biosciences Inc. | Methods for assessing mucosal healing in Crohn's disease patients |
WO2019147824A1 (en) | 2018-01-26 | 2019-08-01 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a pde4 inhibitor |
EP3773573A4 (en) | 2018-04-12 | 2022-04-06 | Morphic Therapeutic, Inc. | ANTAGONISTS OF HUMAN INTEGRIN (ALPHA4) (BETA7) |
WO2019246313A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a tnf inhibitor |
US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
EP3810268A1 (en) | 2018-06-20 | 2021-04-28 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor |
US20230033021A1 (en) | 2018-06-20 | 2023-02-02 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an integrin inhibitor |
US20230009902A1 (en) | 2018-06-20 | 2023-01-12 | Progenity, Inc. | Treatment of a disease or condition in a tissue orginating from the endoderm |
WO2019246273A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a jak or other kinase inhibitor |
WO2020117795A1 (en) * | 2018-12-04 | 2020-06-11 | Prometheus Biosciences, Inc. | Assessment and monitoring of mucosal healing in children and adults with crohn's disease |
TWI802477B (zh) | 2019-10-16 | 2023-05-11 | 美商莫菲克醫療股份有限公司 | 抑制人類整合素α4β7 |
WO2022026699A1 (en) * | 2020-07-31 | 2022-02-03 | Genentech, Inc. | Anti-integrin beta7 antibody formulations and devices |
CN118139896A (zh) * | 2021-10-15 | 2024-06-04 | 南通壹宸生物医药科技有限公司 | 一种双特异性结合分子 |
TW202330613A (zh) * | 2021-11-12 | 2023-08-01 | 美商建南德克公司 | 使用整聯蛋白β7拮抗劑治療克隆氏病之方法 |
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-
2016
- 2016-02-25 EP EP21184652.2A patent/EP3978530A1/en active Pending
- 2016-02-25 AR ARP160100498A patent/AR103782A1/es unknown
- 2016-02-25 CA CA2972099A patent/CA2972099A1/en active Pending
- 2016-02-25 KR KR1020177023210A patent/KR20170120601A/ko not_active Application Discontinuation
- 2016-02-25 JP JP2017545295A patent/JP2018507868A/ja active Pending
- 2016-02-25 MX MX2017010336A patent/MX2017010336A/es unknown
- 2016-02-25 CN CN201680012164.3A patent/CN107257693A/zh active Pending
- 2016-02-25 WO PCT/US2016/019468 patent/WO2016138207A1/en active Application Filing
- 2016-02-25 CN CN202110281006.0A patent/CN113209289A/zh active Pending
- 2016-02-25 EP EP16708894.7A patent/EP3262072A1/en not_active Withdrawn
- 2016-02-25 AU AU2016222683A patent/AU2016222683A1/en not_active Abandoned
-
2017
- 2017-06-22 IL IL253130A patent/IL253130B2/en unknown
- 2017-08-21 US US15/681,881 patent/US20180086833A1/en not_active Abandoned
-
2018
- 2018-03-19 HK HK18103814.8A patent/HK1244229A1/zh unknown
-
2020
- 2020-02-19 US US16/795,296 patent/US20200392232A1/en not_active Abandoned
-
2021
- 2021-11-24 AU AU2021273587A patent/AU2021273587A1/en active Pending
-
2022
- 2022-01-21 JP JP2022007509A patent/JP2022064930A/ja active Pending
- 2022-02-03 US US17/592,227 patent/US20220403034A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2021273587A1 (en) | 2021-12-16 |
IL253130A0 (en) | 2017-08-31 |
KR20170120601A (ko) | 2017-10-31 |
CN113209289A (zh) | 2021-08-06 |
US20180086833A1 (en) | 2018-03-29 |
EP3262072A1 (en) | 2018-01-03 |
EP3978530A1 (en) | 2022-04-06 |
JP2018507868A (ja) | 2018-03-22 |
CA2972099A1 (en) | 2016-09-01 |
US20220403034A1 (en) | 2022-12-22 |
IL253130B1 (en) | 2023-03-01 |
US20200392232A1 (en) | 2020-12-17 |
WO2016138207A1 (en) | 2016-09-01 |
IL253130B2 (en) | 2023-07-01 |
HK1244229A1 (zh) | 2018-08-03 |
MX2017010336A (es) | 2017-12-20 |
AU2016222683A1 (en) | 2017-07-13 |
JP2022064930A (ja) | 2022-04-26 |
CN107257693A (zh) | 2017-10-17 |
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