JOP20190100A1 - بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامها - Google Patents
بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامهاInfo
- Publication number
- JOP20190100A1 JOP20190100A1 JOP/2019/0100A JOP20190100A JOP20190100A1 JO P20190100 A1 JOP20190100 A1 JO P20190100A1 JO P20190100 A JOP20190100 A JO P20190100A JO P20190100 A1 JOP20190100 A1 JO P20190100A1
- Authority
- JO
- Jordan
- Prior art keywords
- methods
- binding proteins
- gitr antigen
- abps
- gitr
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Abstract
يتعلق الاختراع الحالي ببروتينات رابطة لمولد ضد (ABPs) ترتبط بانتقائية بـ GITR وصوره المتماثلة ونظائره، وتركيبات تشتمل على ABPs. ويتم أيضا تقديم طرق استخدام ABPs، مثل الطرق العلاجية والتشخيصية.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662497428P | 2016-11-19 | 2016-11-19 | |
US201762448644P | 2017-01-20 | 2017-01-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
JOP20190100A1 true JOP20190100A1 (ar) | 2019-05-01 |
Family
ID=62146165
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2019/0100A JOP20190100A1 (ar) | 2016-11-19 | 2017-06-16 | بروتينات ربط مولد ضد مضاد لـ gitr وطرق استخدامها |
Country Status (17)
Country | Link |
---|---|
US (2) | US10988545B2 (ar) |
EP (1) | EP3541845A1 (ar) |
JP (1) | JP2019537449A (ar) |
KR (1) | KR102574071B1 (ar) |
CN (1) | CN110248960A (ar) |
AU (1) | AU2017362721A1 (ar) |
BR (1) | BR112019010128A2 (ar) |
CO (1) | CO2019006424A2 (ar) |
IL (1) | IL266720A (ar) |
JO (1) | JOP20190100A1 (ar) |
MA (1) | MA46844A (ar) |
MX (1) | MX2019005821A (ar) |
PH (1) | PH12019501108A1 (ar) |
TW (1) | TWI783953B (ar) |
UA (1) | UA126389C2 (ar) |
WO (1) | WO2018094300A1 (ar) |
ZA (1) | ZA201902939B (ar) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102239781B1 (ko) * | 2019-04-08 | 2021-04-13 | 주식회사 녹십자 | Gpnmb 및 cd3에 특이적으로 결합하는 이중특이적 항체 및 이의 용도 |
US10994021B1 (en) * | 2020-04-11 | 2021-05-04 | Bliss Biopharmaceutical (Hangzhou) Co., Ltd. | Tetravalent antibody-drug conjugates and use thereof |
US20230233707A1 (en) | 2020-06-08 | 2023-07-27 | University Of Washington | Antibody-bound nanoparticles |
KR102475255B1 (ko) * | 2021-05-10 | 2022-12-09 | 메디맵바이오 주식회사 | 항-gitr 항체 및 이의 용도 |
WO2023094507A1 (en) * | 2021-11-24 | 2023-06-01 | Formycon Ag | Improved ace2 fusion proteins |
WO2023175614A1 (en) | 2022-03-15 | 2023-09-21 | Yeda Research And Development Co. Ltd. | Anti glucocorticoid-induced tnfr-related (gitr) protein antibodies and uses thereof |
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2017
- 2017-06-16 JO JOP/2019/0100A patent/JOP20190100A1/ar unknown
- 2017-11-19 CN CN201780071351.3A patent/CN110248960A/zh active Pending
- 2017-11-19 MA MA046844A patent/MA46844A/fr unknown
- 2017-11-19 KR KR1020197017116A patent/KR102574071B1/ko active IP Right Grant
- 2017-11-19 JP JP2019527171A patent/JP2019537449A/ja active Pending
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- 2017-11-19 UA UAA201906793A patent/UA126389C2/uk unknown
- 2017-11-19 WO PCT/US2017/062443 patent/WO2018094300A1/en unknown
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2018
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US10988545B2 (en) | 2021-04-27 |
IL266720A (en) | 2019-07-31 |
RU2019118800A3 (ar) | 2021-03-23 |
KR102574071B1 (ko) | 2023-09-06 |
BR112019010128A2 (pt) | 2019-10-08 |
WO2018094300A8 (en) | 2019-05-02 |
WO2018094300A1 (en) | 2018-05-24 |
AU2017362721A1 (en) | 2019-05-23 |
CN110248960A (zh) | 2019-09-17 |
PH12019501108A1 (en) | 2019-07-29 |
US20180208665A1 (en) | 2018-07-26 |
RU2019118800A (ru) | 2020-12-21 |
TWI783953B (zh) | 2022-11-21 |
UA126389C2 (uk) | 2022-09-28 |
EP3541845A1 (en) | 2019-09-25 |
MX2019005821A (es) | 2019-10-07 |
CO2019006424A2 (es) | 2019-08-20 |
JP2019537449A (ja) | 2019-12-26 |
ZA201902939B (en) | 2022-08-31 |
MA46844A (fr) | 2019-09-25 |
US20210269542A1 (en) | 2021-09-02 |
KR20190095298A (ko) | 2019-08-14 |
TW201819416A (zh) | 2018-06-01 |
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