SG10201701380TA - Biomarkers and methods of treating pd-1 and pd-l1 related conditions - Google Patents

Biomarkers and methods of treating pd-1 and pd-l1 related conditions

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Publication number
SG10201701380TA
SG10201701380TA SG10201701380TA SG10201701380TA SG10201701380TA SG 10201701380T A SG10201701380T A SG 10201701380TA SG 10201701380T A SG10201701380T A SG 10201701380TA SG 10201701380T A SG10201701380T A SG 10201701380TA SG 10201701380T A SG10201701380T A SG 10201701380TA
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Singapore
Prior art keywords
biomarkers
treating
methods
related conditions
conditions
Prior art date
Application number
SG10201701380TA
Inventor
Daniel Shin-Yu Chen
Priti Hegde
Hartmut Koeppen
Marcin Kowanetz
Original Assignee
Genentech Inc
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Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of SG10201701380TA publication Critical patent/SG10201701380TA/en

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    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin
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    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70532B7 molecules, e.g. CD80, CD86
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    • G01MEASURING; TESTING
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SG10201701380TA 2013-03-15 2014-03-12 Biomarkers and methods of treating pd-1 and pd-l1 related conditions SG10201701380TA (en)

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Application Number Priority Date Filing Date Title
US201361802296P 2013-03-15 2013-03-15
US201361812678P 2013-04-16 2013-04-16
US201361829236P 2013-05-30 2013-05-30
US201361883186P 2013-09-26 2013-09-26

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EP (3) EP4356960A2 (en)
JP (2) JP6483082B2 (en)
KR (5) KR20220053691A (en)
CN (2) CN105209919B (en)
AU (4) AU2014235453A1 (en)
BR (1) BR112015023120A2 (en)
CA (2) CA3180286A1 (en)
ES (1) ES2761260T3 (en)
HK (1) HK1212769A1 (en)
IL (2) IL241309B (en)
MX (2) MX2015011774A (en)
MY (2) MY197809A (en)
NZ (3) NZ712314A (en)
PL (1) PL2972373T3 (en)
RU (1) RU2701378C2 (en)
SG (2) SG10201701380TA (en)
WO (1) WO2014151006A2 (en)

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