EP0760012A4 - Method of detecting compounds utilizing genetically modified lambdoid bacteriophage - Google Patents

Method of detecting compounds utilizing genetically modified lambdoid bacteriophage

Info

Publication number
EP0760012A4
EP0760012A4 EP94920140A EP94920140A EP0760012A4 EP 0760012 A4 EP0760012 A4 EP 0760012A4 EP 94920140 A EP94920140 A EP 94920140A EP 94920140 A EP94920140 A EP 94920140A EP 0760012 A4 EP0760012 A4 EP 0760012A4
Authority
EP
European Patent Office
Prior art keywords
genetically modified
detecting compounds
compounds utilizing
lambdoid bacteriophage
utilizing genetically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94920140A
Other languages
German (de)
French (fr)
Other versions
EP0760012A1 (en
Inventor
Bryan L Ray
Edmund C C Lin
Roberto Crea
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Symbiotech Inc
Original Assignee
Symbiotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symbiotech Inc filed Critical Symbiotech Inc
Publication of EP0760012A1 publication Critical patent/EP0760012A1/en
Publication of EP0760012A4 publication Critical patent/EP0760012A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP94920140A 1994-06-10 1994-06-10 Method of detecting compounds utilizing genetically modified lambdoid bacteriophage Withdrawn EP0760012A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/006543 WO1995034683A1 (en) 1994-06-10 1994-06-10 Method of detecting compounds utilizing genetically modified lambdoid bacteriophage

Publications (2)

Publication Number Publication Date
EP0760012A1 EP0760012A1 (en) 1997-03-05
EP0760012A4 true EP0760012A4 (en) 1997-07-02

Family

ID=22242658

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94920140A Withdrawn EP0760012A4 (en) 1994-06-10 1994-06-10 Method of detecting compounds utilizing genetically modified lambdoid bacteriophage

Country Status (3)

Country Link
EP (1) EP0760012A4 (en)
AU (1) AU7104294A (en)
WO (1) WO1995034683A1 (en)

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ATE164395T1 (en) * 1990-12-03 1998-04-15 Genentech Inc METHOD FOR ENRICHMENT OF PROTEIN VARIANTS WITH MODIFIED BINDING PROPERTIES
EP1100890A2 (en) 1998-07-27 2001-05-23 Genentech, Inc. Improved transformation efficiency in phage display through modification of a coat protein
ES2242620T3 (en) 1999-06-14 2005-11-16 Genentech, Inc. PEPTIDIC STRUCTURES TO DISPLAY LIBRARIES OF TURNS OF A PAYMENT.
US6914123B2 (en) 2001-04-17 2005-07-05 Genentech, Inc. Hairpin peptides with a novel structural motif and methods relating thereto
US20070160576A1 (en) 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
ES2372321T3 (en) 2001-06-20 2012-01-18 Genentech, Inc. COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF A LUNG TUMOR.
KR101008758B1 (en) 2001-09-18 2011-01-14 제넨테크, 인크. Compositions and Methods for the Diagnosis and Treatment of Tumor
KR100623128B1 (en) 2002-01-02 2006-09-14 제넨테크, 인크. Compositions and Methods for the Diagnosis and Treatment of Tumor
EP2011886A3 (en) 2002-04-16 2009-02-11 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
NZ544317A (en) 2003-07-08 2009-05-31 Genentech Inc IL-17 A/F heterologous polypeptides and therapeutic uses thereof
US7329725B1 (en) 2003-10-29 2008-02-12 Nastech Pharmaceutical Company Inc. Phage displayed Trp cage ligands
ES2472690T3 (en) 2003-11-17 2014-07-02 Genentech, Inc. Antibody against CD22 for the treatment of tumors of hematopoietic origin
RU2007137489A (en) 2005-03-10 2009-04-20 Дженентек, Инк. (Us) METHODS AND COMPOSITIONS FOR MODULATION OF VESSEL INTEGRITY
WO2007126455A2 (en) 2006-04-05 2007-11-08 Genentech, Inc. Method for using boc/cdo to modulate hedgehog signaling
EP2520935A3 (en) 2006-08-09 2013-02-13 Homestead Clinical Corporation Organ-specific proteins and methods of their use
EP2083017A4 (en) 2006-09-14 2011-01-12 Med & Biological Lab Co Ltd Antibody having enhanced adcc activity and method for production thereof
ES2379413T3 (en) 2007-02-22 2012-04-25 Genentech, Inc. Procedures to detect inflammatory bowel disease
EP2319869B1 (en) 2008-06-20 2016-08-17 National University Corporation Okayama University ANTIBODY AGAINST OXIDIZED LDL/ß²GPI COMPLEX AND USE OF THE SAME
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
EP2360172B1 (en) 2008-10-20 2017-10-18 Gwangju Institute of Science and Technology Bipodal peptide binder
EP3187877A1 (en) 2009-09-25 2017-07-05 XOMA Technology Ltd. Screening methods
ES2564207T3 (en) 2009-10-22 2016-03-18 F. Hoffmann-La Roche Ag Methods and compositions for modulating hepsin activation of macrophage stimulating protein
EP3002297B1 (en) 2009-11-30 2020-04-08 F. Hoffmann-La Roche AG Antibodies for treating and diagnosing tumors expressing slc34a2 (tat211)
KR20130004579A (en) 2010-02-23 2013-01-11 제넨테크, 인크. Compositions and methods for the diagnosis and treatment of tumor
RU2636461C2 (en) 2010-05-03 2017-11-23 Дженентек, Инк. Compositions and methods for diagnosis and treatment of tumour
GB2503604B (en) 2011-03-21 2020-04-22 Biodesy Llc Classification of kinase inhibitors using second harmonic optical techniques
CA2846083A1 (en) 2011-09-15 2013-03-21 Genentech, Inc. Methods of promoting differentiation
WO2013056148A2 (en) 2011-10-15 2013-04-18 Genentech, Inc. Methods of using scd1 antagonists
WO2013109856A2 (en) 2012-01-18 2013-07-25 Genentech, Inc. Methods of using fgf19 modulators
JP6545959B2 (en) 2012-02-11 2019-07-17 ジェネンテック， インコーポレイテッド R-Spondin rearrangement and method of using the same
US9139863B2 (en) 2012-03-16 2015-09-22 Genentech, Inc. Engineered conformationally-stabilized proteins
EP2825549B1 (en) 2012-03-16 2018-10-10 F. Hoffmann-La Roche SA Engineered conformationally-stabilized proteins
MX2014010953A (en) 2012-03-16 2014-10-13 Hoffmann La Roche Methods of treating melanoma with pak1 inhibitors.
JP6302460B2 (en) 2012-04-25 2018-03-28 バイオデシー， インコーポレイテッド Methods for detecting allosteric modulators of proteins
WO2013170191A1 (en) 2012-05-11 2013-11-14 Genentech, Inc. Methods of using antagonists of nad biosynthesis from nicotinamide
MY176706A (en) 2013-03-15 2020-08-19 Genentech Inc Biomarkers and methods of treating pd-1 and pd-l1 related conditions
WO2015116902A1 (en) 2014-01-31 2015-08-06 Genentech, Inc. G-protein coupled receptors in hedgehog signaling
KR20170005016A (en) 2014-05-23 2017-01-11 제넨테크, 인크. Mit biomarkers and methods using the same
CN114057857A (en) 2014-06-20 2022-02-18 豪夫迈·罗氏有限公司 CHAGASIN-based scaffold compositions, methods and uses
WO2016106286A1 (en) 2014-12-23 2016-06-30 Biodesy, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
WO2016172485A2 (en) 2015-04-24 2016-10-27 Genentech, Inc. Multispecific antigen-binding proteins
WO2018049275A1 (en) 2016-09-09 2018-03-15 Genentech, Inc. Selective peptide inhibitors of frizzled
WO2018152496A1 (en) 2017-02-17 2018-08-23 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Compositions and methods for the diagnosis and treatment of zika virus infection
EP3615569A1 (en) 2017-04-25 2020-03-04 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Antibodies and methods for the diagnosis and treatment of epstein barr virus infection
EP3655430A1 (en) 2017-07-19 2020-05-27 The U.S.A. as represented by the Secretary, Department of Health and Human Services Antibodies and methods for the diagnosis and treatment of hepatitis b virus infection
JP7397884B2 (en) 2019-05-09 2023-12-13 ジェネンテック， インコーポレイテッド How to make antibodies

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717705A (en) * 1969-01-16 1973-02-20 M Sela Protein-bacteriophage conjugates
WO1988006630A1 (en) * 1987-03-02 1988-09-07 Genex Corporation Method for the preparation of binding molecules

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717705A (en) * 1969-01-16 1973-02-20 M Sela Protein-bacteriophage conjugates
WO1988006630A1 (en) * 1987-03-02 1988-09-07 Genex Corporation Method for the preparation of binding molecules

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
I. KATSURA.: "Mechanism of length determination in Bacteriophage Lambda tails.", ADV. BIOPHYS., vol. 26, 1990, pages 1 - 18, XP000646027 *
I.N. MARUYAMA ET AL.: "Lambda foo: a lambda phage vector for the expression of foreign proteins.", PROC. NATL. ACAD. SCI. USA, vol. 91, no. 17, August 1994 (1994-08-01), pages 8273 - 8277, XP000647491 *
N.K. ABULADZE ET AL.: "Tail length determination in bacteriophage T4", VIROLOGY, vol. 199, March 1994 (1994-03-01), pages 301 - 310, XP000647480 *
S.F. PARMLEY ET AL.: "Antibody-selectable filamentous fd phage vectors: affinity purification of target genes.", GENE, vol. 73, 1988, pages 305 - 318, XP002029963 *
See also references of WO9534683A1 *

Also Published As

Publication number Publication date
WO1995034683A1 (en) 1995-12-21
AU7104294A (en) 1996-01-05
EP0760012A1 (en) 1997-03-05

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