SG11201507333XA - Biomarkers and methods of treating pd-1 and pd-l1 related conditions - Google Patents
Biomarkers and methods of treating pd-1 and pd-l1 related conditionsInfo
- Publication number
- SG11201507333XA SG11201507333XA SG11201507333XA SG11201507333XA SG11201507333XA SG 11201507333X A SG11201507333X A SG 11201507333XA SG 11201507333X A SG11201507333X A SG 11201507333XA SG 11201507333X A SG11201507333X A SG 11201507333XA SG 11201507333X A SG11201507333X A SG 11201507333XA
- Authority
- SG
- Singapore
- Prior art keywords
- biomarkers
- treating
- methods
- related conditions
- conditions
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
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- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361802296P | 2013-03-15 | 2013-03-15 | |
US201361812678P | 2013-04-16 | 2013-04-16 | |
US201361829236P | 2013-05-30 | 2013-05-30 | |
US201361883186P | 2013-09-26 | 2013-09-26 | |
PCT/US2014/024746 WO2014151006A2 (en) | 2013-03-15 | 2014-03-12 | Biomarkers and methods of treating pd-1 and pd-l1 related conditions |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201507333XA true SG11201507333XA (en) | 2015-10-29 |
Family
ID=50391526
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201507333XA SG11201507333XA (en) | 2013-03-15 | 2014-03-12 | Biomarkers and methods of treating pd-1 and pd-l1 related conditions |
SG10201701380TA SG10201701380TA (en) | 2013-03-15 | 2014-03-12 | Biomarkers and methods of treating pd-1 and pd-l1 related conditions |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201701380TA SG10201701380TA (en) | 2013-03-15 | 2014-03-12 | Biomarkers and methods of treating pd-1 and pd-l1 related conditions |
Country Status (18)
Country | Link |
---|---|
US (2) | US11299544B2 (en) |
EP (2) | EP2972373B1 (en) |
JP (2) | JP6483082B2 (en) |
KR (5) | KR102158924B1 (en) |
CN (2) | CN110079599A (en) |
AU (4) | AU2014235453A1 (en) |
BR (1) | BR112015023120A2 (en) |
CA (2) | CA2905798C (en) |
ES (1) | ES2761260T3 (en) |
HK (1) | HK1212769A1 (en) |
IL (2) | IL241309B (en) |
MX (2) | MX2015011774A (en) |
MY (2) | MY197809A (en) |
NZ (3) | NZ712314A (en) |
PL (1) | PL2972373T3 (en) |
RU (1) | RU2701378C2 (en) |
SG (2) | SG11201507333XA (en) |
WO (1) | WO2014151006A2 (en) |
Families Citing this family (133)
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CN104655854A (en) | 2008-04-09 | 2015-05-27 | 健泰科生物技术公司 | Novel compositions and methods for the treatment of immune related diseases |
DK2376535T3 (en) | 2008-12-09 | 2017-06-12 | Hoffmann La Roche | ANTI-PD-L1 ANTIBODIES AND THEIR USE TO PROMOTE T CELL FUNCTION |
AU2010310688A1 (en) | 2009-10-21 | 2012-05-17 | Epic Sciences, Inc. | Method of using non-rare cells to detect rare cells |
ES2705950T3 (en) | 2011-06-03 | 2019-03-27 | Eisai R&D Man Co Ltd | Biomarkers to predict and assess the responsiveness of subjects with thyroid and kidney cancer to lenvatinib compounds |
US9308236B2 (en) | 2013-03-15 | 2016-04-12 | Bristol-Myers Squibb Company | Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions |
WO2015009856A2 (en) | 2013-07-16 | 2015-01-22 | Genentech, Inc. | Methods of treating cancer using pd-1 axis binding antagonists and tigit inhibitors |
WO2015094995A2 (en) * | 2013-12-17 | 2015-06-25 | Merck Sharp & Dohme Corp. | Gene signature biomarkers of tumor response to pd-1 antagonists |
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KR20170083563A (en) | 2014-11-14 | 2017-07-18 | 리퀴드 제노믹스, 아이엔씨. | Use of circulating cell-free rna for diagnosis and/or monitoring cancer |
ES2744936T3 (en) * | 2014-12-02 | 2020-02-26 | Univ Tokyo | Method to evaluate the therapeutic effect of an antineoplastic agent that has an anti-CD4 antibody as active ingredient |
RU2017123117A (en) * | 2014-12-09 | 2019-01-10 | Мерк Шарп И Доум Корп. | SYSTEM AND METHODS FOR PRODUCING BIOMARKERS OF GENE SIGNATURES OF RESPONSE TO PD-1 ANTAGONISTS |
US9861680B2 (en) | 2014-12-18 | 2018-01-09 | Bristol-Myers Squibb Company | Immunomodulators |
US9944678B2 (en) | 2014-12-19 | 2018-04-17 | Bristol-Myers Squibb Company | Immunomodulators |
EP3252469A1 (en) * | 2015-01-29 | 2017-12-06 | Konica Minolta, Inc. | Method for simultaneous detection of blood cells having interacting molecules |
US20160222060A1 (en) | 2015-02-04 | 2016-08-04 | Bristol-Myers Squibb Company | Immunomodulators |
JP6885869B2 (en) | 2015-02-26 | 2021-06-16 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | PD-1 / PD-L1 Inhibitors for Treating Cancer |
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EP3268392A2 (en) | 2015-03-13 | 2018-01-17 | CytomX Therapeutics, Inc. | Anti-pdl1 antibodies, activatable anti-pdl1 antibodies, and methods of use thereof |
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BR112018011029A2 (en) | 2016-01-08 | 2018-11-21 | Hoffmann La Roche | methods for treating or delaying cancer progression and improving immune function in a cancer individual, uses of a binding antagonist and a bispecific antibody, compositions and kits |
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