FI973543A - Menetelmä heteromultimeeristen polypeptidien valmistamiseksi - Google Patents

Menetelmä heteromultimeeristen polypeptidien valmistamiseksi Download PDF

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Publication number
FI973543A
FI973543A FI973543A FI973543A FI973543A FI 973543 A FI973543 A FI 973543A FI 973543 A FI973543 A FI 973543A FI 973543 A FI973543 A FI 973543A FI 973543 A FI973543 A FI 973543A
Authority
FI
Finland
Prior art keywords
heteromultimeric polypeptides
preparing
preparing heteromultimeric
polypeptides
heteromultimeric
Prior art date
Application number
FI973543A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI973543A0 (fi
Inventor
Paul J Carter
Leonard G Presta
John B Ridgway
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of FI973543A publication Critical patent/FI973543A/fi
Publication of FI973543A0 publication Critical patent/FI973543A0/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI973543A 1995-03-01 1997-08-28 Menetelmä heteromultimeeristen polypeptidien valmistamiseksi FI973543A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/399,106 US5731168A (en) 1995-03-01 1995-03-01 Method for making heteromultimeric polypeptides
PCT/US1996/001598 WO1996027011A1 (en) 1995-03-01 1996-02-05 A method for making heteromultimeric polypeptides

Publications (2)

Publication Number Publication Date
FI973543A true FI973543A (fi) 1997-08-28
FI973543A0 FI973543A0 (fi) 1997-08-28

Family

ID=23578173

Family Applications (1)

Application Number Title Priority Date Filing Date
FI973543A FI973543A0 (fi) 1995-03-01 1997-08-28 Menetelmä heteromultimeeristen polypeptidien valmistamiseksi

Country Status (18)

Country Link
US (7) US5731168A (xx)
EP (1) EP0812357B1 (xx)
JP (1) JP3775798B2 (xx)
CN (1) CN1176659A (xx)
AU (1) AU702737B2 (xx)
BR (1) BR9607622A (xx)
CA (1) CA2211459C (xx)
DE (1) DE69636831T2 (xx)
DK (1) DK0812357T3 (xx)
ES (1) ES2281080T3 (xx)
FI (1) FI973543A0 (xx)
IL (1) IL117274A (xx)
MX (1) MX9706493A (xx)
NO (1) NO973982L (xx)
NZ (1) NZ303425A (xx)
PT (1) PT812357E (xx)
WO (1) WO1996027011A1 (xx)
ZA (1) ZA961635B (xx)

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IL117274A (en) 2000-07-16
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NO973982L (no) 1997-11-03
MX9706493A (es) 1997-11-29
US5807706A (en) 1998-09-15
CA2211459A1 (en) 1996-09-06
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US20070014794A1 (en) 2007-01-18
EP0812357A1 (en) 1997-12-17
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US7695936B2 (en) 2010-04-13
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US5731168A (en) 1998-03-24
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JP3775798B2 (ja) 2006-05-17
DE69636831D1 (de) 2007-02-22
US8679785B2 (en) 2014-03-25
FI973543A0 (fi) 1997-08-28
NZ303425A (en) 1999-07-29
NO973982D0 (no) 1997-08-29
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CA2211459C (en) 2009-11-17
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US5821333A (en) 1998-10-13
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