SG11201608054YA - Method for detecting multispecific antibody light chain mispairing - Google Patents

Method for detecting multispecific antibody light chain mispairing

Info

Publication number
SG11201608054YA
SG11201608054YA SG11201608054YA SG11201608054YA SG11201608054YA SG 11201608054Y A SG11201608054Y A SG 11201608054YA SG 11201608054Y A SG11201608054Y A SG 11201608054YA SG 11201608054Y A SG11201608054Y A SG 11201608054YA SG 11201608054Y A SG11201608054Y A SG 11201608054YA
Authority
SG
Singapore
Prior art keywords
detecting
method
light chain
antibody light
multispecific antibody
Prior art date
Application number
SG11201608054YA
Inventor
Michael Molhoj
Maximiliane Koenig
Vincent Larraillet
Katja Montan
Bianca Gruenwalder
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP14163165 priority Critical
Priority to EP15155361 priority
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to PCT/EP2015/057164 priority patent/WO2015150446A1/en
Publication of SG11201608054YA publication Critical patent/SG11201608054YA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/6857Antibody fragments
SG11201608054YA 2014-04-02 2015-04-01 Method for detecting multispecific antibody light chain mispairing SG11201608054YA (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP14163165 2014-04-02
EP15155361 2015-02-17
PCT/EP2015/057164 WO2015150446A1 (en) 2014-04-02 2015-04-01 Method for detecting multispecific antibody light chain mispairing

Publications (1)

Publication Number Publication Date
SG11201608054YA true SG11201608054YA (en) 2016-10-28

Family

ID=52774264

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201608054YA SG11201608054YA (en) 2014-04-02 2015-04-01 Method for detecting multispecific antibody light chain mispairing

Country Status (7)

Country Link
US (1) US20170115304A1 (en)
EP (1) EP3126389A1 (en)
JP (1) JP2017509669A (en)
KR (1) KR20160140723A (en)
CN (1) CN106164288A (en)
SG (1) SG11201608054YA (en)
WO (1) WO2015150446A1 (en)

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Also Published As

Publication number Publication date
EP3126389A1 (en) 2017-02-08
US20170115304A1 (en) 2017-04-27
KR20160140723A (en) 2016-12-07
CN106164288A (en) 2016-11-23
WO2015150446A1 (en) 2015-10-08
JP2017509669A (en) 2017-04-06

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