MX341074B - Polipeptidos heterologos il-17 a/f y usos terapeuticos de los mismos. - Google Patents

Polipeptidos heterologos il-17 a/f y usos terapeuticos de los mismos.

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Publication number
MX341074B
MX341074B MX2013009629A MX2013009629A MX341074B MX 341074 B MX341074 B MX 341074B MX 2013009629 A MX2013009629 A MX 2013009629A MX 2013009629 A MX2013009629 A MX 2013009629A MX 341074 B MX341074 B MX 341074B
Authority
MX
Mexico
Prior art keywords
present
polypeptides
interleukin
methods
therapeutic uses
Prior art date
Application number
MX2013009629A
Other languages
English (en)
Inventor
Arnott David
Gurney Austin
Hass Philip
Lee James
Wu Yan
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34107720&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX341074(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX341074B publication Critical patent/MX341074B/es

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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Abstract

La presente invención se refiere a una nueva citosina humana de origen natural que esta comprendida de un heterodímero de interleucina-17 e interleucina 17F designada en la presente como interleucina 17A/F (IL-17A/F). También se proporcionan en la presente vectores y células huésped que comprenden esas secuencias de ácido nucleico, moléculas de polipéptido quiméricas que comprenden los polipéptidos de la presente invención fusionados a secuencias de polipéptidos heterólogas, anticuerpos específicos que se enlazan a los polipéptidos de la presente invención y a métodos para producir los polipéptidos de la presente invención. Además se proporcionan en la presente métodos para tratar trastornos cartilaginosos degenerativos y otras enfermedades inflamatorias.
MX2013009629A 2003-07-08 2004-06-02 Polipeptidos heterologos il-17 a/f y usos terapeuticos de los mismos. MX341074B (es)

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