GB1325209A - Pharmaceutical composition - Google Patents

Pharmaceutical composition

Info

Publication number
GB1325209A
GB1325209A GB5054170A GB5054170A GB1325209A GB 1325209 A GB1325209 A GB 1325209A GB 5054170 A GB5054170 A GB 5054170A GB 5054170 A GB5054170 A GB 5054170A GB 1325209 A GB1325209 A GB 1325209A
Authority
GB
United Kingdom
Prior art keywords
particles
polylactide
drug
lactide
ethynyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5054170A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of GB1325209A publication Critical patent/GB1325209A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB5054170A 1969-10-23 1970-10-23 Pharmaceutical composition Expired GB1325209A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86889969A 1969-10-23 1969-10-23
US7930970A 1970-10-08 1970-10-08

Publications (1)

Publication Number Publication Date
GB1325209A true GB1325209A (en) 1973-08-01

Family

ID=26761845

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5054170A Expired GB1325209A (en) 1969-10-23 1970-10-23 Pharmaceutical composition

Country Status (6)

Country Link
US (1) US3773919A (enExample)
JP (1) JPS5017525B1 (enExample)
CA (1) CA982479A (enExample)
DE (1) DE2051580C3 (enExample)
FR (1) FR2070153B1 (enExample)
GB (1) GB1325209A (enExample)

Cited By (13)

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EP0086627A1 (en) * 1982-02-12 1983-08-24 Unitika Ltd. Anti-cancer device
EP0094513A3 (en) * 1982-05-14 1984-08-22 Akzo Gmbh Sustained-release body containing an active ingredient
US4526938A (en) * 1982-04-22 1985-07-02 Imperial Chemical Industries Plc Continuous release formulations
EP0134318A3 (en) * 1983-06-10 1986-08-20 Connaught Laboratories Limited Controlled release of injectable and implantable insulin compositions
AT382076B (de) * 1982-10-15 1987-01-12 Chemie Linz Ag Verfahren zur herstellung von presslingen mit retardierter wirkstofffreisetzung
US4767628A (en) * 1981-02-16 1988-08-30 Imperial Chemical Industries Plc Continuous release pharmaceutical compositions
US4874612A (en) * 1987-02-12 1989-10-17 Hoechst Aktiengesellschaft Multi-component long-acting medicament formulation for implantation
WO1996012466A1 (en) * 1994-10-25 1996-05-02 Daratech Pty. Ltd. Controlled release container with core and outer shell
US5776885A (en) * 1987-09-21 1998-07-07 Debio Recherche Pharmaceutique Sa Sustained and controlled release of water insoluble polypeptides
CN1057442C (zh) * 1990-06-14 2000-10-18 药物应用合股公司 用于胃肠外注射的药物组合物的制备方法
CN1058608C (zh) * 1990-06-14 2000-11-22 药物应用合股公司 非胃肠道给药药物组合物的制备方法
US6174299B1 (en) 1991-09-09 2001-01-16 Harvey B. Pollard Method for treating hemophilia A and B and AIDS and devices used therein
EP3458070A4 (en) * 2016-05-16 2020-01-08 Amag Pharmaceuticals, Inc. PROLONGED RELEASE POLYMER COMPOSITIONS BASED ON HYDROXYPROGESTERONE CAPROATE AND METHODS OF USE THEREOF

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US4767628A (en) * 1981-02-16 1988-08-30 Imperial Chemical Industries Plc Continuous release pharmaceutical compositions
EP0086627A1 (en) * 1982-02-12 1983-08-24 Unitika Ltd. Anti-cancer device
US4526938A (en) * 1982-04-22 1985-07-02 Imperial Chemical Industries Plc Continuous release formulations
EP0094513A3 (en) * 1982-05-14 1984-08-22 Akzo Gmbh Sustained-release body containing an active ingredient
AT382076B (de) * 1982-10-15 1987-01-12 Chemie Linz Ag Verfahren zur herstellung von presslingen mit retardierter wirkstofffreisetzung
EP0134318A3 (en) * 1983-06-10 1986-08-20 Connaught Laboratories Limited Controlled release of injectable and implantable insulin compositions
US4874612A (en) * 1987-02-12 1989-10-17 Hoechst Aktiengesellschaft Multi-component long-acting medicament formulation for implantation
US5776885A (en) * 1987-09-21 1998-07-07 Debio Recherche Pharmaceutique Sa Sustained and controlled release of water insoluble polypeptides
CN1057442C (zh) * 1990-06-14 2000-10-18 药物应用合股公司 用于胃肠外注射的药物组合物的制备方法
CN1058608C (zh) * 1990-06-14 2000-11-22 药物应用合股公司 非胃肠道给药药物组合物的制备方法
US6174299B1 (en) 1991-09-09 2001-01-16 Harvey B. Pollard Method for treating hemophilia A and B and AIDS and devices used therein
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US5916584A (en) * 1994-10-25 1999-06-29 Daratech Proprietary Limited Controlled release container with core and outer shell
EP3458070A4 (en) * 2016-05-16 2020-01-08 Amag Pharmaceuticals, Inc. PROLONGED RELEASE POLYMER COMPOSITIONS BASED ON HYDROXYPROGESTERONE CAPROATE AND METHODS OF USE THEREOF

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US3773919A (en) 1973-11-20
CA982479A (en) 1976-01-27
JPS5017525B1 (enExample) 1975-06-21
FR2070153B1 (enExample) 1975-01-10
DE2051580A1 (de) 1971-05-06
DE2051580B2 (de) 1980-07-10
DE2051580C3 (de) 1981-04-02
FR2070153A1 (enExample) 1971-09-10

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