MX377528B - Compuestos de platino funcionalizados con monomaleimida para la terapia del cáncer. - Google Patents

Compuestos de platino funcionalizados con monomaleimida para la terapia del cáncer.

Info

Publication number
MX377528B
MX377528B MX2018006953A MX2018006953A MX377528B MX 377528 B MX377528 B MX 377528B MX 2018006953 A MX2018006953 A MX 2018006953A MX 2018006953 A MX2018006953 A MX 2018006953A MX 377528 B MX377528 B MX 377528B
Authority
MX
Mexico
Prior art keywords
monomaleimide
platinum compounds
cancer therapy
functionalized
functionalized platinum
Prior art date
Application number
MX2018006953A
Other languages
English (en)
Other versions
MX2018006953A (es
Inventor
Bernhard K Keppler
Christian Kowol
Josef Mayr
Petra Heffeter
Verena Pichler
Walter Berger
Original Assignee
Univ Wien Med
Univ Wien
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wien Med, Univ Wien filed Critical Univ Wien Med
Publication of MX2018006953A publication Critical patent/MX2018006953A/es
Publication of MX377528B publication Critical patent/MX377528B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a compuestos de platino funcionalizados con monomaleimida novedosos de la fórmula (I), incluyendo en particular derivados de oxaliplatino y carboplatino funcionalizados con monomaleimida novedosos, así como su uso como medicamentos, particularmente para el tratamiento o prevención del cáncer.( ver formula)
MX2018006953A 2015-12-09 2016-12-09 Compuestos de platino funcionalizados con monomaleimida para la terapia del cáncer. MX377528B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15198739 2015-12-09
PCT/EP2016/080453 WO2017097986A1 (en) 2015-12-09 2016-12-09 Monomaleimide-functionalized platinum compounds for cancer therapy

Publications (2)

Publication Number Publication Date
MX2018006953A MX2018006953A (es) 2019-05-16
MX377528B true MX377528B (es) 2025-03-10

Family

ID=54849106

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018006953A MX377528B (es) 2015-12-09 2016-12-09 Compuestos de platino funcionalizados con monomaleimida para la terapia del cáncer.

Country Status (21)

Country Link
US (2) US10723748B2 (es)
EP (1) EP3386997B1 (es)
JP (1) JP6867652B2 (es)
CN (1) CN108368143B (es)
AU (1) AU2016367306B2 (es)
CA (1) CA3004630A1 (es)
CY (1) CY1124529T1 (es)
DK (1) DK3386997T3 (es)
ES (1) ES2898704T3 (es)
HR (1) HRP20211466T1 (es)
HU (1) HUE056897T2 (es)
IL (1) IL259864B (es)
LT (1) LT3386997T (es)
MX (1) MX377528B (es)
PL (1) PL3386997T3 (es)
PT (1) PT3386997T (es)
RS (1) RS62412B1 (es)
SG (1) SG11201804885TA (es)
SI (1) SI3386997T1 (es)
SM (1) SMT202100709T1 (es)
WO (1) WO2017097986A1 (es)

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TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
CN109171001A (zh) * 2018-09-14 2019-01-11 上海烟草集团有限责任公司 草酸钠在降低卷烟烟气中TSNAs释放量中的应用
WO2021138215A1 (en) * 2019-12-31 2021-07-08 Kinnate Biopharma Inc. Treatment of cancer with cdk12/13 inhibitors
US20230339997A1 (en) * 2020-09-11 2023-10-26 Shanghai Haiju Biological Technology Co., Ltd. Class of platinum compounds for treating cancer, and method for preparation thereof
CN114163479B (zh) * 2020-09-11 2025-05-16 上海海聚生物科技有限公司 一类治疗癌症用的铂类化合物及其制备方法
CN114539320B (zh) * 2020-11-25 2026-01-27 北京大学 辐射激活的四价铂配合物及其用途

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Also Published As

Publication number Publication date
MX2018006953A (es) 2019-05-16
SI3386997T1 (sl) 2021-11-30
ES2898704T3 (es) 2022-03-08
EP3386997A1 (en) 2018-10-17
CY1124529T1 (el) 2022-07-22
SMT202100709T1 (it) 2022-01-10
DK3386997T3 (da) 2021-09-20
CN108368143A (zh) 2018-08-03
US20180354979A1 (en) 2018-12-13
US11572379B2 (en) 2023-02-07
CA3004630A1 (en) 2017-06-15
AU2016367306B2 (en) 2021-04-22
SG11201804885TA (en) 2018-07-30
US20210002313A1 (en) 2021-01-07
EP3386997B1 (en) 2021-06-30
PL3386997T3 (pl) 2021-12-13
JP2018538292A (ja) 2018-12-27
LT3386997T (lt) 2021-12-10
RS62412B1 (sr) 2021-10-29
HUE056897T2 (hu) 2022-03-28
AU2016367306A1 (en) 2018-06-14
HRP20211466T1 (hr) 2021-12-24
IL259864B (en) 2022-07-01
PT3386997T (pt) 2021-11-04
WO2017097986A1 (en) 2017-06-15
US10723748B2 (en) 2020-07-28
JP6867652B2 (ja) 2021-05-12
IL259864A (en) 2018-07-31
CN108368143B (zh) 2022-02-01

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