SG11201804885TA - Monomaleimide-functionalized platinum compounds for cancer therapy - Google Patents

Monomaleimide-functionalized platinum compounds for cancer therapy

Info

Publication number
SG11201804885TA
SG11201804885TA SG11201804885TA SG11201804885TA SG11201804885TA SG 11201804885T A SG11201804885T A SG 11201804885TA SG 11201804885T A SG11201804885T A SG 11201804885TA SG 11201804885T A SG11201804885T A SG 11201804885TA SG 11201804885T A SG11201804885T A SG 11201804885TA
Authority
SG
Singapore
Prior art keywords
wien
international
monomaleimide
pct
platinum compounds
Prior art date
Application number
SG11201804885TA
Other languages
English (en)
Inventor
Christian Kowol
Petra Heffeter
Walter Berger
Bernhard K Keppler
Josef Mayr
Verena Pichler
Original Assignee
Univ Wien Med
Univ Wien
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wien Med, Univ Wien filed Critical Univ Wien Med
Publication of SG11201804885TA publication Critical patent/SG11201804885TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201804885TA 2015-12-09 2016-12-09 Monomaleimide-functionalized platinum compounds for cancer therapy SG11201804885TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15198739 2015-12-09
PCT/EP2016/080453 WO2017097986A1 (en) 2015-12-09 2016-12-09 Monomaleimide-functionalized platinum compounds for cancer therapy

Publications (1)

Publication Number Publication Date
SG11201804885TA true SG11201804885TA (en) 2018-07-30

Family

ID=54849106

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201804885TA SG11201804885TA (en) 2015-12-09 2016-12-09 Monomaleimide-functionalized platinum compounds for cancer therapy

Country Status (20)

Country Link
US (2) US10723748B2 (es)
EP (1) EP3386997B1 (es)
JP (1) JP6867652B2 (es)
CN (1) CN108368143B (es)
AU (1) AU2016367306B2 (es)
CA (1) CA3004630A1 (es)
CY (1) CY1124529T1 (es)
DK (1) DK3386997T3 (es)
ES (1) ES2898704T3 (es)
HR (1) HRP20211466T1 (es)
HU (1) HUE056897T2 (es)
IL (1) IL259864B (es)
LT (1) LT3386997T (es)
MX (1) MX2018006953A (es)
PL (1) PL3386997T3 (es)
PT (1) PT3386997T (es)
RS (1) RS62412B1 (es)
SG (1) SG11201804885TA (es)
SI (1) SI3386997T1 (es)
WO (1) WO2017097986A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3797768A1 (en) * 2014-06-23 2021-03-31 Placon Therapeutics, Inc. Maleimide-functionalised platinum for use in the treatment of cancer
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Hdac抑制劑與pd-l1抑制劑之組合治療
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
CN109171001A (zh) * 2018-09-14 2019-01-11 上海烟草集团有限责任公司 草酸钠在降低卷烟烟气中TSNAs释放量中的应用
CN114163479A (zh) * 2020-09-11 2022-03-11 上海海聚生物科技有限公司 一类治疗癌症用的铂类化合物及其制备方法
US20230339997A1 (en) * 2020-09-11 2023-10-26 Shanghai Haiju Biological Technology Co., Ltd. Class of platinum compounds for treating cancer, and method for preparation thereof
CN114539320A (zh) * 2020-11-25 2022-05-27 北京大学 辐射激活的四价铂配合物及其用途

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
CH588505A5 (es) 1972-06-08 1977-06-15 Research Corp
US4263428A (en) 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
DE3169595D1 (en) 1980-11-10 1985-05-02 Gersonde Klaus Method of preparing lipid vesicles by ultrasonic treatment, the use of this method and apparatus for its application
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
DE3374837D1 (en) 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
DE3218121A1 (de) 1982-05-14 1983-11-17 Leskovar, Peter, Dr.-Ing., 8000 München Arzneimittel zur tumorbehandlung
EP0102324A3 (de) 1982-07-29 1984-11-07 Ciba-Geigy Ag Lipide und Tenside in wässriger Phase
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
JPS607934A (ja) 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd リポソ−ムの製造方法
HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
ATE159858T1 (de) 1983-09-26 1997-11-15 Ehrenfeld Udo Mittel und erzeugnis für die diagnose und therapie von tumoren sowie zur behandlung von schwächen der zelligen und humoralen immunabwehr
EP0143949B1 (en) 1983-11-01 1988-10-12 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Pharmaceutical composition containing urokinase
CS269719B1 (en) 1986-12-29 1990-05-14 Kiss Frantisek Platinum cytostatic
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
DE19636889A1 (de) 1996-09-11 1998-03-12 Felix Dr Kratz Antineoplastisch wirkende Transferrin- und Albuminkonjugate zytostatischer Verbindungen aus der Gruppe der Anthrazykline, Alkylantien, Antimetabolite und Cisplatin-Analoga und diese enthaltende Arzneimittel
BR9812693A (pt) 1997-09-29 2000-08-22 Inhale Therapeutic Syst Uso de um agente bioativo, processo para formar uma microestrutura perfurada, microestrutura perfurada, processo para aumentar a dispersibilidade de um pó, pó de microestrutura perfurada, pó tendo dispersibilidade aumentada, sistema de inalação para a administração pulmonar de um agente bioativo a um paciente, e, processo para a liberação pulmonar de um ou mais agentes bioativos
US7112324B1 (en) 1998-04-21 2006-09-26 Micromet Ag CD 19×CD3 specific polypeptides and uses thereof
DE19926154A1 (de) 1999-06-09 2000-12-14 Ktb Tumorforschungs Gmbh Verfahren zur Herstellung einer injizierbaren Arzneimittelzubereitung
AUPQ641100A0 (en) 2000-03-23 2000-04-15 Australia Nuclear Science & Technology Organisation Methods of synthesis and use of radiolabelled platinum chemotherapeutic ag ents
PT1280520E (pt) 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
TWI324518B (en) 2001-12-19 2010-05-11 Nektar Therapeutics Pulmonary delivery of aminoglycosides
DE10314780A1 (de) 2003-03-19 2004-09-30 Ktb Tumorforschungsgesellschaft Mbh Proteinbindende Derivate von Platinkomplexen mit Cyclobutan-1,1-dicarboxylatliganden
RS20050714A (sr) 2003-03-31 2008-04-04 Pliva-Lachema A.S., Farmaceutski preparati koji kao aktivnu suptancu sadrže kompleks platine i postupci za njihovo dobijanje
CZ2004945A3 (cs) 2004-09-08 2006-01-11 Pliva - Lachema A. S. Farmaceutická kompozice pro rektální nebo vaginální podání, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
CZ296459B6 (cs) 2004-09-14 2006-03-15 Pliva-Lachema A. S. Perorální farmaceutická kompozice pro cílený transport komplexu platiny do kolorektální oblasti, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
US20060205810A1 (en) 2004-11-24 2006-09-14 Schering Corporation Platinum therapeutic combinations
CZ300424B6 (cs) 2006-06-20 2009-05-13 Pliva - Lachema A. S. Farmaceutická kompozice pro perorální podání
CZ300590B6 (cs) 2006-06-20 2009-06-24 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CZ300120B6 (cs) 2006-06-20 2009-02-11 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CA2857398A1 (en) 2011-12-05 2013-06-13 Igenica Biotherapeutics, Inc. Antibody-drug conjugates and related compounds, compositions, and methods
CN107496932A (zh) * 2012-02-27 2017-12-22 阿穆尼克斯运营公司 Xten缀合组合物和制造其的方法
BR112016006955A2 (pt) * 2013-10-08 2017-08-01 Atlas Genetics Ltd compostos de marcação e seu uso em ensaios
WO2015102922A1 (en) * 2013-12-31 2015-07-09 Blend Therapeutics, Inc. Compounds, compositions, and methods for the treatment of cancers
EP3797768A1 (en) * 2014-06-23 2021-03-31 Placon Therapeutics, Inc. Maleimide-functionalised platinum for use in the treatment of cancer
WO2016209935A1 (en) 2015-06-23 2016-12-29 Placon Therapeutics, Inc. Platinum compounds, compositions, and uses thereof
JP6876631B2 (ja) 2015-06-23 2021-05-26 プラコン セラピューティクス インコーポレイテッドPlacon Therapeutics,Inc. 白金化合物、組成物及びその使用
EP3313527B1 (en) 2015-06-29 2021-02-24 Case Western Reserve University Anticancer drug-containing plant virus particles
EP3319936A4 (en) 2015-07-12 2019-02-06 Suzhou M-conj Biotech Co., Ltd. PLACES OF CONDUCT FOR THE CONJUGATION OF CELL BINDING MOLECULES
EP3464280B1 (en) 2016-06-06 2021-10-06 F. Hoffmann-La Roche AG Silvestrol antibody-drug conjugates and methods of use
JP2019524706A (ja) 2016-07-08 2019-09-05 ジェネンテック, インコーポレイテッド Muc16陽性癌治療の応答性を評価するためのヒト精巣上体タンパク質4(he4)の使用
WO2018026742A1 (en) 2016-08-01 2018-02-08 Askgene Pharma Inc. Novel antibody-albumin-drug conjugates (aadc) and methods for using them
CN108164512B (zh) 2017-12-27 2021-05-25 沈阳药科大学 一类具有生物粘附作用的马来酰亚胺型前药及其在口服药物传递中的应用
CN108187063B (zh) 2018-01-09 2020-09-08 沈阳药科大学 白蛋白结合型抗肿瘤药-马来酰亚胺分子前药

Also Published As

Publication number Publication date
US10723748B2 (en) 2020-07-28
CY1124529T1 (el) 2022-07-22
HRP20211466T1 (hr) 2021-12-24
PT3386997T (pt) 2021-11-04
LT3386997T (lt) 2021-12-10
EP3386997B1 (en) 2021-06-30
PL3386997T3 (pl) 2021-12-13
JP6867652B2 (ja) 2021-05-12
MX2018006953A (es) 2019-05-16
RS62412B1 (sr) 2021-10-29
HUE056897T2 (hu) 2022-03-28
IL259864B (en) 2022-07-01
ES2898704T3 (es) 2022-03-08
US11572379B2 (en) 2023-02-07
US20180354979A1 (en) 2018-12-13
AU2016367306B2 (en) 2021-04-22
CA3004630A1 (en) 2017-06-15
IL259864A (en) 2018-07-31
AU2016367306A1 (en) 2018-06-14
JP2018538292A (ja) 2018-12-27
WO2017097986A1 (en) 2017-06-15
CN108368143B (zh) 2022-02-01
US20210002313A1 (en) 2021-01-07
DK3386997T3 (da) 2021-09-20
EP3386997A1 (en) 2018-10-17
CN108368143A (zh) 2018-08-03
SI3386997T1 (sl) 2021-11-30

Similar Documents

Publication Publication Date Title
SG11201804885TA (en) Monomaleimide-functionalized platinum compounds for cancer therapy
SG11201808990QA (en) Compositions for topical application of compounds
SG11201811431VA (en) Multispecific antibodies against cd40 and cd137
SG11201900163PA (en) Macrocycle kinase inhibitors
SG11201805888SA (en) Cyclic dinucleotides for treating conditions associated with sting activity such as cancer
SG11201804814YA (en) Materials and methods for delivering nucleic acids to cochlear and vestibular cells
SG11201407537YA (en) Mutant selectivity and combinations of a phosphoinositide 3 kinase inhibitor compound and chemotherapeutic agents for the treatment of cancer
SG11201806863WA (en) Tetracyclic pyridone compounds as antivirals
SG11201811564QA (en) Methods of treating ovarian cancer
SG11201500005SA (en) Pyrimidine pyrazolyl derivatives
SG11201407859YA (en) Methods of treating cancer using pd-l1 axis binding antagonists and vegf antagonists
SG11201808222RA (en) Methods of treatment of cholestatic diseases
SG11201906436VA (en) Novel heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same
SG11201808237UA (en) Substituted indole compound derivatives as dengue viral replication inhibitors
SG11201408318RA (en) Compositions and methods for transmucosal absorption
SG11201804890TA (en) Bipyrazolyl derivatives useful for the treatment of autoimmune diseases
SG11201811230RA (en) Compositions and methods for reducing ocular neovascularization
SG11201808106YA (en) Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation
SG11201908325PA (en) Process for the preparation of glucuronide drug-linkers and intermediates thereof
SG11201902531QA (en) Liquid pharmaceutical composition
SG11201804704PA (en) Compositions and methods for decreasing tau expression
SG11201901389XA (en) Combination therapy with glutaminase inhibitors
SG11202000333UA (en) Bicyclic ketone compounds and methods of use thereof
SG11201809537VA (en) Urea motif containing compounds and derivatives thereof as antibacterial drugs
SG11201809882XA (en) Pharmaceutical combinations for treating cancer