BRPI0807952A2 - Sistemas de hipermutação somática - Google Patents

Sistemas de hipermutação somática

Info

Publication number
BRPI0807952A2
BRPI0807952A2 BRPI0807952-8A2A BRPI0807952A BRPI0807952A2 BR PI0807952 A2 BRPI0807952 A2 BR PI0807952A2 BR PI0807952 A BRPI0807952 A BR PI0807952A BR PI0807952 A2 BRPI0807952 A2 BR PI0807952A2
Authority
BR
Brazil
Prior art keywords
somatic hypermutation
systems
hypermutation systems
somatic
hypermutation
Prior art date
Application number
BRPI0807952-8A2A
Other languages
English (en)
Inventor
Robert A Horlick
Andrew B Cubitt
Peter M Bowers
Original Assignee
Anaptysbio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anaptysbio Inc filed Critical Anaptysbio Inc
Publication of BRPI0807952A2 publication Critical patent/BRPI0807952A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BRPI0807952-8A2A 2007-02-20 2008-02-20 Sistemas de hipermutação somática BRPI0807952A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90241407P 2007-02-20 2007-02-20
US90462207P 2007-03-01 2007-03-01
US99597007P 2007-09-28 2007-09-28
US2012408P 2008-01-09 2008-01-09
PCT/US2008/002397 WO2008103475A1 (en) 2007-02-20 2008-02-20 Somatic hypermutation systems

Publications (1)

Publication Number Publication Date
BRPI0807952A2 true BRPI0807952A2 (pt) 2014-06-10

Family

ID=39710412

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0807952-8A2A BRPI0807952A2 (pt) 2007-02-20 2008-02-20 Sistemas de hipermutação somática

Country Status (8)

Country Link
US (7) US20090075378A1 (pt)
EP (2) EP2126105A4 (pt)
JP (3) JP5675109B2 (pt)
AU (1) AU2008218925A1 (pt)
BR (1) BRPI0807952A2 (pt)
CA (1) CA2678451A1 (pt)
NZ (1) NZ579010A (pt)
WO (2) WO2008103475A1 (pt)

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