FR2070153A1 - - Google Patents

Info

Publication number
FR2070153A1
FR2070153A1 FR7038364A FR7038364A FR2070153A1 FR 2070153 A1 FR2070153 A1 FR 2070153A1 FR 7038364 A FR7038364 A FR 7038364A FR 7038364 A FR7038364 A FR 7038364A FR 2070153 A1 FR2070153 A1 FR 2070153A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7038364A
Other languages
French (fr)
Other versions
FR2070153B1 (enExample
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of FR2070153A1 publication Critical patent/FR2070153A1/fr
Application granted granted Critical
Publication of FR2070153B1 publication Critical patent/FR2070153B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7038364A 1969-10-23 1970-10-23 Expired FR2070153B1 (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86889969A 1969-10-23 1969-10-23
US7930970A 1970-10-08 1970-10-08

Publications (2)

Publication Number Publication Date
FR2070153A1 true FR2070153A1 (enExample) 1971-09-10
FR2070153B1 FR2070153B1 (enExample) 1975-01-10

Family

ID=26761845

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7038364A Expired FR2070153B1 (enExample) 1969-10-23 1970-10-23

Country Status (6)

Country Link
US (1) US3773919A (enExample)
JP (1) JPS5017525B1 (enExample)
CA (1) CA982479A (enExample)
DE (1) DE2051580C3 (enExample)
FR (1) FR2070153B1 (enExample)
GB (1) GB1325209A (enExample)

Cited By (20)

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FR2165941A1 (enExample) * 1971-12-30 1973-08-10 Xerox Corp
FR2400950A1 (fr) * 1977-08-25 1979-03-23 Sandoz Sa Procede de preparation de microspheres comportant un noyau solide et une matiere polymere
FR2404436A1 (fr) * 1977-09-28 1979-04-27 Ethicon Inc Compositions pharmaceutiques absorbables a base de poly (alcoylene oxalates)
EP0025698A3 (en) * 1979-09-12 1981-12-02 Eli Lilly And Company Controlled release formulations and method of treatment
FR2484281A1 (fr) * 1980-06-13 1981-12-18 Sandoz Sa Procede de preparation de microspheres comportant un noyau solide et une matiere polymere
EP0108882A1 (de) * 1982-10-15 1984-05-23 Chemie Linz Aktiengesellschaft Presslinge mit retardierter Wirkstofffreisetzung und Verfahren zu deren Herstellung
EP0257369A1 (en) * 1986-08-11 1988-03-02 American Cyanamid Company Improved estradiol implant composition and method for preparation
EP0301969A1 (fr) * 1987-07-30 1989-02-01 La Region Wallonne Microparticules comportant un polymère biodégradable contrôlant la libération d'un principe actif antimalarique, compositions pharmaceutiques en comprenant et procédé de préparation
EP0315875A1 (de) * 1987-11-11 1989-05-17 Hoechst Aktiengesellschaft Verfahren zur Herstellung von bioabbaubaren Mikrokapseln wasserlöslicher Peptide und Proteine sowie nach diesem Verfahren erhaltene Mikrokapseln
US4835139A (en) * 1983-09-23 1989-05-30 Debiopharm S.A. Process for increasing the antagonistic effect of peptidic compounds on hormone-dependent diseases
EP0275961A3 (en) * 1987-01-21 1990-11-22 Boehringer Ingelheim Kg Oral medical preparation with subtained release
FR2649319A1 (fr) * 1989-07-07 1991-01-11 Sandoz Sa Formulations a liberation prolongee de peptides solubles dans l'eau
EP0423484A1 (de) * 1989-10-16 1991-04-24 PCD-Polymere Gesellschaft m.b.H. Pressling mit retardierter Wirkstofffreisetzung
FR2654337A1 (fr) * 1989-11-15 1991-05-17 Roussel Uclaf Nouvelles microspheres injectables biodegradables procede de preparation et suspensions injectables les renfermant.
FR2663223A1 (fr) * 1990-06-14 1991-12-20 Af Aplicaciones Far Lab Forme galenique parenterale.
WO1991019485A1 (fr) * 1990-06-14 1991-12-26 Aplicaciones Farmaceuticas, S.A. De C.V. Forme galenique injectable retardee
FR2705232A1 (fr) * 1993-05-15 1994-11-25 Scras Procédé pour la préparation de particules préparées à sec, particules préparées à sec ainsi obtenues et compositions pharmaceutiques contenant de telles particules.
US5433751A (en) * 1992-04-03 1995-07-18 Inoteb Bone prosthesis material containing calcium carbonate particles dispersed in a bioresorbable polymer matrix
WO1999036057A1 (en) * 1998-01-19 1999-07-22 Korea Research Institute Of Chemical Technology Controlled releasing antibiotics preparation
WO1999036071A1 (en) * 1998-01-19 1999-07-22 Korea Research Institute Of Chemical Technology Biodegradable polymer matrices for sustained delivery of anesthetics

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US4419340A (en) * 1969-03-24 1983-12-06 University Of Delaware Controlled release of anticancer agents from biodegradable polymers
US3993073A (en) * 1969-04-01 1976-11-23 Alza Corporation Novel drug delivery device
US3993071A (en) * 1971-09-09 1976-11-23 Alza Corporation Bioerodible ocular device
US3960150A (en) * 1971-09-09 1976-06-01 Alza Corporation Bioerodible ocular device
US3986510A (en) * 1971-09-09 1976-10-19 Alza Corporation Bioerodible ocular device
US3981303A (en) * 1971-09-09 1976-09-21 Alza Corporation Bioerodible ocular device
US3962414A (en) * 1972-04-27 1976-06-08 Alza Corporation Structured bioerodible drug delivery device
US4351337A (en) * 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
US3991766A (en) * 1973-05-31 1976-11-16 American Cyanamid Company Controlled release of medicaments using polymers from glycolic acid
US4001388A (en) * 1973-06-14 1977-01-04 Alza Corporation Ophthalmological bioerodible drug dispensing formulation
US3914402A (en) * 1973-06-14 1975-10-21 Alza Corp Ophthalmic dosage form, for releasing medication over time
US3976071A (en) * 1974-01-07 1976-08-24 Dynatech Corporation Methods of improving control of release rates and products useful in same
US3982537A (en) * 1974-12-30 1976-09-28 Louis Bucalo Dynamic implants and method for implanting the same
US4054138A (en) * 1974-12-30 1977-10-18 Louis Bucalo Implants for acting on living beings
US4076798A (en) * 1975-05-29 1978-02-28 American Cyanamid Company High molecular weight polyester resin, the method of making the same and the use thereof as a pharmaceutical composition
US4011312A (en) * 1975-06-25 1977-03-08 American Home Products Corporation Prolonged release drug form for the treatment of bovine mastitis
US4115544A (en) * 1976-08-18 1978-09-19 Alza Corporation Ocular system made of bioerodible esters having linear ether
HU174057B (hu) * 1976-09-17 1979-10-28 Richter Gedeon Vegyeszet Sostav dlja pokrytij obespechivajuhhij uregulirovannuju otdachy aktivnogo vehhestva biologicheski aktivnykh preparatov i sposob poluchenija takikh preparatov s uregulirovannoj otdachej aktivnogo vehhestva
US4328204A (en) * 1977-03-02 1982-05-04 Ethicon, Inc. Absorbable polymer-drug compounds and method for making same
WO1978000011A1 (fr) * 1977-06-07 1978-12-21 Garching Instrumente Forme d'implant medicamenteux et procede de preparation
US4148871A (en) * 1977-10-11 1979-04-10 Pitt Colin G Sustained subdermal delivery ofdrugs using poly(ε-caprolactone) and its copolymers
DE2843963A1 (de) * 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
US4159322A (en) * 1978-06-26 1979-06-26 A. H. Robins Company, Inc. Anticoccidium implants
GB2026862A (en) * 1978-08-04 1980-02-13 Robins Co Inc A H Filaricide implants containing diethylcarbamazine
US4272398A (en) * 1978-08-17 1981-06-09 The United States Of America As Represented By The Secretary Of Agriculture Microencapsulation process
US4585651A (en) * 1978-10-17 1986-04-29 Stolle Research & Development Corporation Active/passive immunization of the internal female reproductive organs
US4732763A (en) * 1978-10-17 1988-03-22 Stolle Research And Development Corporation Active/passive immunization of the internal female reproductive organs
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US4622244A (en) * 1979-09-04 1986-11-11 The Washington University Process for preparation of microcapsules
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US4273920A (en) * 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
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US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
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US4637905A (en) * 1982-03-04 1987-01-20 Batelle Development Corporation Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or ε-caprolactones
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US5248700A (en) * 1982-05-14 1993-09-28 Akzo Nv Active agent containing solid structures for prolonged release of active agents
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US4523591A (en) * 1982-10-22 1985-06-18 Kaplan Donald S Polymers for injection molding of absorbable surgical devices
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FR2165941A1 (enExample) * 1971-12-30 1973-08-10 Xerox Corp
FR2400950A1 (fr) * 1977-08-25 1979-03-23 Sandoz Sa Procede de preparation de microspheres comportant un noyau solide et une matiere polymere
FR2404436A1 (fr) * 1977-09-28 1979-04-27 Ethicon Inc Compositions pharmaceutiques absorbables a base de poly (alcoylene oxalates)
EP0025698A3 (en) * 1979-09-12 1981-12-02 Eli Lilly And Company Controlled release formulations and method of treatment
FR2484281A1 (fr) * 1980-06-13 1981-12-18 Sandoz Sa Procede de preparation de microspheres comportant un noyau solide et une matiere polymere
EP0108882A1 (de) * 1982-10-15 1984-05-23 Chemie Linz Aktiengesellschaft Presslinge mit retardierter Wirkstofffreisetzung und Verfahren zu deren Herstellung
US4835139A (en) * 1983-09-23 1989-05-30 Debiopharm S.A. Process for increasing the antagonistic effect of peptidic compounds on hormone-dependent diseases
EP0257369A1 (en) * 1986-08-11 1988-03-02 American Cyanamid Company Improved estradiol implant composition and method for preparation
EP0275961A3 (en) * 1987-01-21 1990-11-22 Boehringer Ingelheim Kg Oral medical preparation with subtained release
FR2618674A1 (fr) * 1987-07-30 1989-02-03 Ire Celltarg Sa Microparticules comportant un polymere biodegradable controlant la liberation d'un principe actif antimalarique, compositions pharmaceutiques en comprenant et procede de preparation
EP0301969A1 (fr) * 1987-07-30 1989-02-01 La Region Wallonne Microparticules comportant un polymère biodégradable contrôlant la libération d'un principe actif antimalarique, compositions pharmaceutiques en comprenant et procédé de préparation
US4897267A (en) * 1987-07-30 1990-01-30 Ire-Celltarg S.A. Microparticles comprising a biodegradable polymer controlling the release of an antimalaria active principle, pharmaceutical compositions comprising it and process for its preparation
EP0315875A1 (de) * 1987-11-11 1989-05-17 Hoechst Aktiengesellschaft Verfahren zur Herstellung von bioabbaubaren Mikrokapseln wasserlöslicher Peptide und Proteine sowie nach diesem Verfahren erhaltene Mikrokapseln
FR2649319A1 (fr) * 1989-07-07 1991-01-11 Sandoz Sa Formulations a liberation prolongee de peptides solubles dans l'eau
BE1004486A3 (fr) * 1989-07-07 1992-12-01 Sandoz Sa Formulations a liberation prolongee de peptides solubles dans l'eau.
EP0423484A1 (de) * 1989-10-16 1991-04-24 PCD-Polymere Gesellschaft m.b.H. Pressling mit retardierter Wirkstofffreisetzung
FR2654337A1 (fr) * 1989-11-15 1991-05-17 Roussel Uclaf Nouvelles microspheres injectables biodegradables procede de preparation et suspensions injectables les renfermant.
BE1005511A4 (fr) * 1989-11-15 1993-08-31 Roussel Uclaf Utilisation de nouvelles microspheres injectables biodegradables, procede de preparation de ces nouvelles microspheres et suspensions injectables les renfermant.
US5633014A (en) * 1990-06-14 1997-05-27 Aplicaciones Farmaceuticas S.A. De C.V. Injectable pharmaceutical composition
WO1991019484A1 (fr) * 1990-06-14 1991-12-26 Aplicaciones Farmaceuticas, S.A. De C.V. Composition pharmaceutique injectable
WO1991019485A1 (fr) * 1990-06-14 1991-12-26 Aplicaciones Farmaceuticas, S.A. De C.V. Forme galenique injectable retardee
FR2663223A1 (fr) * 1990-06-14 1991-12-20 Af Aplicaciones Far Lab Forme galenique parenterale.
US5433751A (en) * 1992-04-03 1995-07-18 Inoteb Bone prosthesis material containing calcium carbonate particles dispersed in a bioresorbable polymer matrix
FR2705232A1 (fr) * 1993-05-15 1994-11-25 Scras Procédé pour la préparation de particules préparées à sec, particules préparées à sec ainsi obtenues et compositions pharmaceutiques contenant de telles particules.
BE1008323A3 (fr) * 1993-05-15 1996-04-02 Sod Conseils Rech Applic Procede pour la preparation de particules preparees a sec, particules preparees a sec ainsi obtenues et compositions pharmaceutiques contenant de telles particules.
ES2097083A1 (es) * 1993-05-15 1997-03-16 Sod Conseils Rech Applic Procedimiento para la preparcion de particulas tratadas en seco, las particulas tratadas en seco asi obtenidas, y composiciones farmaceuticas que contienen tales particulas.
AT406017B (de) * 1993-05-15 2000-01-25 Sod Conseils Rech Applic Verfahren zur herstelung von teilchen, so erhaltene teilchen und solche teilchen enthaltende pharmazeutische massen
CN1050534C (zh) * 1993-05-15 2000-03-22 科学研究与运用咨询公司 干法处理的粒子的制备方法
WO1999036057A1 (en) * 1998-01-19 1999-07-22 Korea Research Institute Of Chemical Technology Controlled releasing antibiotics preparation
WO1999036071A1 (en) * 1998-01-19 1999-07-22 Korea Research Institute Of Chemical Technology Biodegradable polymer matrices for sustained delivery of anesthetics

Also Published As

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DE2051580C3 (de) 1981-04-02
CA982479A (en) 1976-01-27
DE2051580B2 (de) 1980-07-10
GB1325209A (en) 1973-08-01
US3773919A (en) 1973-11-20
JPS5017525B1 (enExample) 1975-06-21
FR2070153B1 (enExample) 1975-01-10
DE2051580A1 (de) 1971-05-06

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