BRPI0506793A - métodos de tratamento de obesidade ou diabetes com o uso de nt-4/5 - Google Patents
métodos de tratamento de obesidade ou diabetes com o uso de nt-4/5Info
- Publication number
- BRPI0506793A BRPI0506793A BRPI0506793-6A BRPI0506793A BRPI0506793A BR PI0506793 A BRPI0506793 A BR PI0506793A BR PI0506793 A BRPI0506793 A BR PI0506793A BR PI0506793 A BRPI0506793 A BR PI0506793A
- Authority
- BR
- Brazil
- Prior art keywords
- obesity
- treatment methods
- diabetes treatment
- polypeptide
- relates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Emergency Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
MéTODOS DE TRATAMENTO DA OBESIDADE OU DIABETES COM O USO DE NT-4/5. invenção refere-se a métodos para tratamento da obesidade, diabetes melito não insulino-dependente, síndrome metabólica e outras doenças relacionadas, por administração de um polipeptídeo NT-4/5. A invenção também se refere a composições farmacêuticas e kits compreendendo um polipeptídeo NT-4/5.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54639004P | 2004-02-20 | 2004-02-20 | |
PCT/US2005/005881 WO2005082401A1 (en) | 2004-02-20 | 2005-02-22 | Methods of treating obesity or diabetes using nt-4/5 |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0506793A true BRPI0506793A (pt) | 2007-05-22 |
Family
ID=34910771
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0506793-6A BRPI0506793A (pt) | 2004-02-20 | 2005-02-22 | métodos de tratamento de obesidade ou diabetes com o uso de nt-4/5 |
Country Status (6)
Country | Link |
---|---|
US (2) | US20050209148A1 (pt) |
EP (1) | EP1720564A1 (pt) |
JP (1) | JP2007523196A (pt) |
BR (1) | BRPI0506793A (pt) |
CA (1) | CA2556923A1 (pt) |
WO (1) | WO2005082401A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007088479A1 (en) * | 2006-02-02 | 2007-08-09 | Rinat Neuroscience Corp. | Methods for treating obesity by administering a trkb antagonist |
JP2009528985A (ja) | 2006-02-02 | 2009-08-13 | ライナット ニューロサイエンス コーポレイション | trkBアゴニストを投与することにより望まれない体重減少または摂食障害を治療する方法 |
US7476405B2 (en) * | 2006-02-23 | 2009-01-13 | Iomedix Sleep International Srl | Compositions and methods for the induction and maintenance of quality sleep |
WO2010086828A2 (en) | 2009-02-02 | 2010-08-05 | Rinat Neuroscience Corporation | Agonist anti-trkb monoclonal antibodies |
WO2011127304A2 (en) * | 2010-04-07 | 2011-10-13 | Zafgen Corporation | Methods of treating an overweight subject |
Family Cites Families (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US4777127A (en) * | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
US5219740A (en) * | 1987-02-13 | 1993-06-15 | Fred Hutchinson Cancer Research Center | Retroviral gene transfer into diploid fibroblasts for gene therapy |
US5364768A (en) * | 1987-07-07 | 1994-11-15 | Farmitalia Carlo Erba S.R.L. | Process for the preparation of penems |
US5422120A (en) * | 1988-05-30 | 1995-06-06 | Depotech Corporation | Heterovesicular liposomes |
US5686579A (en) * | 1988-06-21 | 1997-11-11 | Hybrisens, Ltd. | Use of antibody/antigen interactions to protect biologically active proteins and peptides |
US5703055A (en) * | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
US6673776B1 (en) * | 1989-03-21 | 2004-01-06 | Vical Incorporated | Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human |
JPH03133378A (ja) * | 1989-07-19 | 1991-06-06 | Modrovich Ivan E | 被験体を安定化させて液体中でのその生物学的活性を保存する方法 |
DE69121208T2 (de) * | 1990-09-25 | 1997-01-23 | Genentech Inc | Neuer neurotropischer faktor |
US6506728B2 (en) * | 1990-09-25 | 2003-01-14 | Genentech, Inc. | Methods using a novel neurotrophic factor, NT-4 |
US6566091B1 (en) * | 1990-09-25 | 2003-05-20 | Genentech, Inc. | Neurotrophic factor |
ES2148144T3 (es) * | 1990-11-20 | 2000-10-16 | Dade Behring Marburg Gmbh | Procedimiento para la estabilizacion de conjugados de enzima. |
EP0666756B1 (en) * | 1992-09-14 | 1999-11-24 | Regeneron Pharmaceuticals, Inc. | Method of producing analgesia using neurotrophins |
US6015686A (en) * | 1993-09-15 | 2000-01-18 | Chiron Viagene, Inc. | Eukaryotic layered vector initiation systems |
US20030191061A1 (en) * | 1994-03-31 | 2003-10-09 | Brewitt Barbara A. | Treatment methods using homeopathic preparations of growth factors |
US6024734A (en) * | 1994-03-31 | 2000-02-15 | Brewitt; Barbara A. | Treatment methods using homeopathic preparations of growth factors |
US6436908B1 (en) * | 1995-05-30 | 2002-08-20 | Duke University | Use of exogenous β-adrenergic receptor and β-adrenergic receptor kinase gene constructs to enhance myocardial function |
WO1995031183A1 (en) * | 1994-05-16 | 1995-11-23 | Washington University | Cell membrane fusion composition and method |
ES2204960T3 (es) * | 1994-06-24 | 2004-05-01 | Dade Behring Marburg Gmbh | Procedimiento para la estabilizacion de moleculas sensibles a la hidrolisis. |
US5770577A (en) * | 1994-11-14 | 1998-06-23 | Amgen Inc. | BDNF and NT-3 polypeptides selectively linked to polyethylene glycol |
US6143718A (en) * | 1995-06-07 | 2000-11-07 | Amylin Pharmaceuticals, Inc. | Treatment of Type II diabetes mellutis with amylin agonists |
EP0938499A1 (en) * | 1996-07-19 | 1999-09-01 | Amgen Inc. | Analogs of cationic proteins |
NZ335207A (en) * | 1996-11-15 | 2000-09-29 | Genentech Inc | Process to isolate recombinant human neurotrophin using hydrophobic chromatography resin |
KR20000070357A (ko) * | 1997-01-23 | 2000-11-25 | 다께우찌 마사야쓰 | 당뇨병 치료제 |
US20030105057A1 (en) * | 1997-03-19 | 2003-06-05 | Yale University | Methods and compositions for stimulating apoptosis and cell death or for inhibiting cell growth and cell attachment |
US8173127B2 (en) * | 1997-04-09 | 2012-05-08 | Intellect Neurosciences, Inc. | Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof |
US6753165B1 (en) * | 1999-01-14 | 2004-06-22 | Bolder Biotechnology, Inc. | Methods for making proteins containing free cysteine residues |
IL134536A0 (en) * | 1997-08-29 | 2001-04-30 | Vertex Pharma | Compounds possessing neuronal activity and pharmaceutical compositions containing the same |
US6376471B1 (en) * | 1997-10-10 | 2002-04-23 | Johns Hopkins University | Gene delivery compositions and methods |
US6565874B1 (en) * | 1998-10-28 | 2003-05-20 | Atrix Laboratories | Polymeric delivery formulations of leuprolide with improved efficacy |
EP1172113A4 (en) * | 1999-04-16 | 2004-06-30 | Sumitomo Pharma | MEDICINE FOR AUTONOMOUS NEUROPATHIES |
US6582945B1 (en) * | 1999-06-16 | 2003-06-24 | Boston Biomedical Research Institute | Immunological control of β-amyloid levels in vivo |
JP2003503482A (ja) * | 1999-07-06 | 2003-01-28 | バーテックス ファーマシューティカルズ インコーポレイテッド | 環化アミノ酸誘導体 |
EP1200440A1 (en) * | 1999-07-06 | 2002-05-02 | Vertex Pharmaceuticals Incorporated | Quinuclidine derivatives for treatment of neurological disorders |
EP1196400A1 (en) * | 1999-07-06 | 2002-04-17 | Vertex Pharmaceuticals Incorporated | Amino-alkyl derivatives |
AU6205700A (en) * | 1999-07-06 | 2001-01-22 | Vertex Pharmaceuticals Incorporated | Azo amino acid derivatives for the treatment of neurological diseases |
AU6071400A (en) * | 1999-07-06 | 2001-01-22 | Vertex Pharmaceuticals Incorporated | Cyclized amide derivatives |
WO2001008685A1 (en) * | 1999-07-30 | 2001-02-08 | Vertex Pharmaceuticals Incorporated | Acyclic and cyclic amine derivatives |
CA2385929A1 (en) * | 1999-10-29 | 2001-05-03 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh | Use of gdnf for treating corneal defects |
US20030022840A1 (en) * | 2000-02-18 | 2003-01-30 | Michiko Kishino | Drugs for ameliorating impaired glucose tolerance |
US20030036512A1 (en) * | 2000-03-06 | 2003-02-20 | Tsutomu Nakagawa | Leptin-resistance amerliorating agents |
RU2004100701A (ru) * | 2001-06-14 | 2005-06-20 | Вертекс Фармасьютикалз Инкорпорейтед (Us) | Ациклические производные пиперазина и пиперидина, которые являются полезными для лечения повреждения нейронов |
US6818613B2 (en) * | 2001-11-07 | 2004-11-16 | Ortho-Mcneil Pharmaceutical, Inc. | Aqueous sustained-release formulations of proteins |
US6712086B1 (en) * | 2002-12-20 | 2004-03-30 | Sidney T. Fails | Above ground meter box |
JP2009528985A (ja) * | 2006-02-02 | 2009-08-13 | ライナット ニューロサイエンス コーポレイション | trkBアゴニストを投与することにより望まれない体重減少または摂食障害を治療する方法 |
-
2005
- 2005-02-22 WO PCT/US2005/005881 patent/WO2005082401A1/en active Application Filing
- 2005-02-22 JP JP2006554325A patent/JP2007523196A/ja active Pending
- 2005-02-22 US US11/064,309 patent/US20050209148A1/en not_active Abandoned
- 2005-02-22 BR BRPI0506793-6A patent/BRPI0506793A/pt not_active IP Right Cessation
- 2005-02-22 CA CA002556923A patent/CA2556923A1/en not_active Abandoned
- 2005-02-22 EP EP05714023A patent/EP1720564A1/en not_active Withdrawn
-
2009
- 2009-03-13 US US12/404,202 patent/US20090203610A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20090203610A1 (en) | 2009-08-13 |
US20050209148A1 (en) | 2005-09-22 |
JP2007523196A (ja) | 2007-08-16 |
WO2005082401A1 (en) | 2005-09-09 |
CA2556923A1 (en) | 2005-09-09 |
EP1720564A1 (en) | 2006-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6 ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2099 DE 29/03/2011. |