HK1214820A1 - 雜芳基吡啶酮和氮雜-吡啶酮酰胺化合物 - Google Patents

雜芳基吡啶酮和氮雜-吡啶酮酰胺化合物

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Publication number
HK1214820A1
HK1214820A1 HK16102768.8A HK16102768A HK1214820A1 HK 1214820 A1 HK1214820 A1 HK 1214820A1 HK 16102768 A HK16102768 A HK 16102768A HK 1214820 A1 HK1214820 A1 HK 1214820A1
Authority
HK
Hong Kong
Prior art keywords
pyridone
aza
heteroaryl
amide compounds
compounds
Prior art date
Application number
HK16102768.8A
Other languages
English (en)
Inventor
James John Crawford
Wendy Lee
Wendy B Young
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1214820A1 publication Critical patent/HK1214820A1/zh

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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HK16102768.8A 2013-07-03 2016-03-10 雜芳基吡啶酮和氮雜-吡啶酮酰胺化合物 HK1214820A1 (zh)

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US201361842648P 2013-07-03 2013-07-03
PCT/EP2014/064044 WO2015000949A1 (en) 2013-07-03 2014-07-02 Heteroaryl pyridone and aza-pyridone amide compounds

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US (1) US9326985B2 (zh)
EP (1) EP3016943B1 (zh)
JP (1) JP6165977B2 (zh)
KR (1) KR101815360B1 (zh)
CN (2) CN110698481B (zh)
BR (1) BR112015029972A2 (zh)
CA (1) CA2912359A1 (zh)
HK (1) HK1214820A1 (zh)
MX (1) MX2015018038A (zh)
RU (1) RU2016101548A (zh)
WO (1) WO2015000949A1 (zh)

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CN104812746B (zh) * 2012-11-16 2017-03-08 弗·哈夫曼-拉罗切有限公司 布鲁顿氏酪氨酸激酶抑制剂
WO2015151006A1 (en) 2014-03-29 2015-10-08 Lupin Limited Substituted purine compounds as btk inhibitors
AU2015240465B2 (en) 2014-04-04 2020-02-27 Del Mar Pharmaceuticals Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer
WO2015170266A1 (en) 2014-05-07 2015-11-12 Lupin Limited Substituted pyrimidine compounds as btk inhibitors
US10077247B2 (en) 2015-01-09 2018-09-18 Ono Pharmaceutical Co., Ltd. Tricyclic spiro compound
US10208024B2 (en) 2015-10-23 2019-02-19 Array Biopharma Inc. 2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2H)-one compounds as inhibitors of FGFR tyrosine kinases
CA3004448A1 (en) * 2015-11-12 2017-05-18 Afasci, Inc. Ion channel inhibitory compounds, pharmaceutical formulations and uses
CN109640997A (zh) * 2016-06-30 2019-04-16 W·西斯 通过抑制Bruton’s酪氨酸激酶(Btk)治疗和预防动脉粥样硬化血栓形成
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