HK1220357A1 - 雜芳基化合物和其用途 - Google Patents
雜芳基化合物和其用途Info
- Publication number
- HK1220357A1 HK1220357A1 HK16108385.8A HK16108385A HK1220357A1 HK 1220357 A1 HK1220357 A1 HK 1220357A1 HK 16108385 A HK16108385 A HK 16108385A HK 1220357 A1 HK1220357 A1 HK 1220357A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- heteroaryl compounds
- heteroaryl
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/80—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361793113P | 2013-03-15 | 2013-03-15 | |
EP14305361 | 2014-03-13 | ||
PCT/US2014/029270 WO2014144737A1 (en) | 2013-03-15 | 2014-03-14 | Heteroaryl compounds and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1220357A1 true HK1220357A1 (zh) | 2017-05-05 |
Family
ID=54252495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16108385.8A HK1220357A1 (zh) | 2013-03-15 | 2016-07-15 | 雜芳基化合物和其用途 |
Country Status (17)
Country | Link |
---|---|
US (2) | US10065966B2 (zh) |
EP (1) | EP3943087A1 (zh) |
KR (1) | KR102350704B1 (zh) |
CA (1) | CA2907243C (zh) |
CL (1) | CL2015002628A1 (zh) |
CR (1) | CR20150524A (zh) |
DO (2) | DOP2015000219A (zh) |
ES (1) | ES2892423T3 (zh) |
HK (1) | HK1220357A1 (zh) |
IL (1) | IL240605B (zh) |
MY (1) | MY181020A (zh) |
NI (1) | NI201500119A (zh) |
NZ (1) | NZ711376A (zh) |
PH (1) | PH12015502041B1 (zh) |
SA (1) | SA515361151B1 (zh) |
TN (1) | TN2015000417A1 (zh) |
UA (1) | UA120248C2 (zh) |
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PT3176170T (pt) | 2012-06-13 | 2019-02-05 | Incyte Holdings Corp | Compostos tricíclicos substituídos como inibidores de fgfr |
AR095464A1 (es) | 2013-03-15 | 2015-10-21 | Celgene Avilomics Res Inc | Compuestos de heteroarilo y usos de los mismos |
EP3943087A1 (en) | 2013-03-15 | 2022-01-26 | Celgene CAR LLC | Heteroaryl compounds and uses thereof |
PE20152033A1 (es) | 2013-04-19 | 2016-01-21 | Incyte Holdings Corp | Heterociclos bicicliclos como inhibidores de fgfr |
DK3116316T3 (da) | 2014-03-13 | 2019-08-19 | Univ Indiana Res & Tech Corp | Allosteriske modulatorer af hepatitis b-kerneprotein |
US10851105B2 (en) | 2014-10-22 | 2020-12-01 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
EP3617205B1 (en) | 2015-02-20 | 2021-08-04 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
MA41551A (fr) | 2015-02-20 | 2017-12-26 | Incyte Corp | Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4 |
TWI730985B (zh) | 2015-09-15 | 2021-06-21 | 美商艾森伯利生物科學公司 | B型肝炎核心蛋白質調節劑 |
WO2018053157A1 (en) | 2016-09-15 | 2018-03-22 | Assembly Biosciences, Inc. | Hepatitis b core protein modulators |
CA3055194A1 (en) | 2017-03-02 | 2018-09-07 | Assembly Biosciences, Inc. | Cyclic sulfamide compounds and methods of using same |
US11040965B2 (en) | 2017-03-13 | 2021-06-22 | Assembly Biosciences, Inc. | Process for making Hepatitis B core protein modulators |
AR111960A1 (es) | 2017-05-26 | 2019-09-04 | Incyte Corp | Formas cristalinas de un inhibidor de fgfr y procesos para su preparación |
CA3099116A1 (en) | 2018-05-04 | 2019-11-07 | Incyte Corporation | Salts of an fgfr inhibitor |
CN112867716A (zh) | 2018-05-04 | 2021-05-28 | 因赛特公司 | Fgfr抑制剂的固体形式和其制备方法 |
WO2020185532A1 (en) | 2019-03-08 | 2020-09-17 | Incyte Corporation | Methods of treating cancer with an fgfr inhibitor |
WO2021007269A1 (en) | 2019-07-09 | 2021-01-14 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
JOP20220083A1 (ar) | 2019-10-14 | 2023-01-30 | Incyte Corp | حلقات غير متجانسة ثنائية الحلقة كمثبطات لـ fgfr |
US11566028B2 (en) | 2019-10-16 | 2023-01-31 | Incyte Corporation | Bicyclic heterocycles as FGFR inhibitors |
CA3162010A1 (en) | 2019-12-04 | 2021-06-10 | Incyte Corporation | Derivatives of an fgfr inhibitor |
CA3163875A1 (en) | 2019-12-04 | 2021-06-10 | Incyte Corporation | Tricyclic heterocycles as fgfr inhibitors |
US11939331B2 (en) | 2021-06-09 | 2024-03-26 | Incyte Corporation | Tricyclic heterocycles as FGFR inhibitors |
CN113340866B (zh) * | 2021-06-28 | 2023-03-31 | 上海应用技术大学 | 一种基于黄色荧光碳量子点检测亚硫酸根离子的方法 |
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2014
- 2014-03-14 EP EP21181253.2A patent/EP3943087A1/en not_active Withdrawn
- 2014-03-14 ES ES14763001T patent/ES2892423T3/es active Active
- 2014-03-14 KR KR1020217004803A patent/KR102350704B1/ko active IP Right Grant
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- 2014-03-14 MY MYPI2015002346A patent/MY181020A/en unknown
- 2014-03-14 UA UAA201508512A patent/UA120248C2/uk unknown
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2015
- 2015-08-17 IL IL240605A patent/IL240605B/en active IP Right Grant
- 2015-09-04 NI NI201500119A patent/NI201500119A/es unknown
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- 2015-09-10 PH PH12015502041A patent/PH12015502041B1/en unknown
- 2015-09-11 CL CL2015002628A patent/CL2015002628A1/es unknown
- 2015-09-11 TN TN2015000417A patent/TN2015000417A1/en unknown
- 2015-09-15 SA SA515361151A patent/SA515361151B1/ar unknown
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2016
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- 2017-05-25 US US15/604,786 patent/US10065966B2/en active Active
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CL2015002628A1 (es) | 2016-08-26 |
NZ711376A (en) | 2020-01-31 |
TN2015000417A1 (en) | 2017-01-03 |
IL240605B (en) | 2020-04-30 |
NI201500119A (es) | 2015-11-18 |
PH12015502041A1 (en) | 2016-01-18 |
KR20210022140A (ko) | 2021-03-02 |
US10065966B2 (en) | 2018-09-04 |
UA120248C2 (uk) | 2019-11-11 |
ES2892423T3 (es) | 2022-02-04 |
EP3943087A1 (en) | 2022-01-26 |
SA515361151B1 (ar) | 2018-09-25 |
DOP2017000015A (es) | 2017-04-16 |
US20170267685A1 (en) | 2017-09-21 |
DOP2015000219A (es) | 2015-11-30 |
US20190218220A1 (en) | 2019-07-18 |
CR20150524A (es) | 2015-12-01 |
MY181020A (en) | 2020-12-16 |
KR102350704B1 (ko) | 2022-01-13 |
CA2907243A1 (en) | 2014-09-18 |
PH12015502041B1 (en) | 2016-01-18 |
CA2907243C (en) | 2021-12-28 |
IL240605A0 (en) | 2015-09-24 |
US10618902B2 (en) | 2020-04-14 |
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