AR111960A1 - Formas cristalinas de un inhibidor de fgfr y procesos para su preparación - Google Patents

Formas cristalinas de un inhibidor de fgfr y procesos para su preparación

Info

Publication number
AR111960A1
AR111960A1 ARP180101392A ARP180101392A AR111960A1 AR 111960 A1 AR111960 A1 AR 111960A1 AR P180101392 A ARP180101392 A AR P180101392A AR P180101392 A ARP180101392 A AR P180101392A AR 111960 A1 AR111960 A1 AR 111960A1
Authority
AR
Argentina
Prior art keywords
processes
preparation
crystalline forms
fgfr inhibitor
solid
Prior art date
Application number
ARP180101392A
Other languages
English (en)
Inventor
Qun Li
Jiacheng Zhou
Zhongjiang Jia
Dengjin Wang
Michael Xia
Wayne Han
Ming Tao
Yongchun Pan
Chongsheng Eric Shi
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of AR111960A1 publication Critical patent/AR111960A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Abstract

Reivindicación 1: Una forma sólida del Compuesto 1 que tiene la fórmula (1), o una sal de este. Reivindicación 2: La forma sólida de la reivindicación 1 en donde la forma sólida es cristalina. Reivindicación 3: La forma sólida de la reivindicación 2 de la Forma I. Reivindicación 12: La forma sólida de la reivindicación 2 que tiene la Forma II, la Forma III, la Forma IV, la Forma V, la Forma VI, la Forma VII, la Forma VIII, la Forma IX, la Forma IXa, la Forma X o la Forma XI.
ARP180101392A 2017-05-26 2018-05-24 Formas cristalinas de un inhibidor de fgfr y procesos para su preparación AR111960A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762511525P 2017-05-26 2017-05-26

Publications (1)

Publication Number Publication Date
AR111960A1 true AR111960A1 (es) 2019-09-04

Family

ID=62685156

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP180101392A AR111960A1 (es) 2017-05-26 2018-05-24 Formas cristalinas de un inhibidor de fgfr y procesos para su preparación

Country Status (20)

Country Link
US (2) US10611762B2 (es)
EP (1) EP3630762A1 (es)
JP (2) JP2020521754A (es)
KR (1) KR20200013700A (es)
CN (2) CN111148745B (es)
AR (1) AR111960A1 (es)
AU (1) AU2018272013B2 (es)
BR (1) BR112019024769A2 (es)
CA (1) CA3064894A1 (es)
CL (1) CL2019003439A1 (es)
CO (1) CO2019014699A2 (es)
CR (1) CR20220454A (es)
EA (1) EA201992794A1 (es)
IL (1) IL270872A (es)
MA (1) MA48779A (es)
MX (1) MX2019014097A (es)
PE (1) PE20200742A1 (es)
PH (1) PH12019502675A1 (es)
TW (1) TW201904966A (es)
WO (1) WO2018218100A1 (es)

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DK3176170T3 (en) 2012-06-13 2019-01-28 Incyte Holdings Corp SUBSTITUTED TRICYCLIC RELATIONS AS FGFR INHIBITORS
ES2893725T3 (es) 2013-04-19 2022-02-09 Incyte Holdings Corp Heterocíclicos bicíclicos como inhibidores del FGFR
US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
MA41551A (fr) 2015-02-20 2017-12-26 Incyte Corp Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
CN107438607B (zh) 2015-02-20 2021-02-05 因赛特公司 作为fgfr抑制剂的双环杂环
AR111960A1 (es) * 2017-05-26 2019-09-04 Incyte Corp Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
MA52493A (fr) 2018-05-04 2021-03-10 Incyte Corp Sels d'un inhibiteur de fgfr
BR112020022392A2 (pt) 2018-05-04 2021-02-02 Incyte Corporation formas sólidas de um inibidor de fgfr e processos para preparação das mesmas
WO2020185532A1 (en) 2019-03-08 2020-09-17 Incyte Corporation Methods of treating cancer with an fgfr inhibitor
CN112142730A (zh) * 2019-06-28 2020-12-29 四川科伦博泰生物医药股份有限公司 杂芳基并四氢吡啶类化合物的固体形式及其制备方法
US11591329B2 (en) 2019-07-09 2023-02-28 Incyte Corporation Bicyclic heterocycles as FGFR inhibitors
CR20220169A (es) 2019-10-14 2022-10-27 Incyte Corp Heterociclos bicíclicos como inhibidores de fgfr
US11566028B2 (en) 2019-10-16 2023-01-31 Incyte Corporation Bicyclic heterocycles as FGFR inhibitors
JP2023505258A (ja) 2019-12-04 2023-02-08 インサイト・コーポレイション Ｆｇｆｒ阻害剤としての三環式複素環
WO2021113462A1 (en) 2019-12-04 2021-06-10 Incyte Corporation Derivatives of an fgfr inhibitor
WO2022261160A1 (en) 2021-06-09 2022-12-15 Incyte Corporation Tricyclic heterocycles as fgfr inhibitors

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