DK2044026T3 - Fremgangsmde til behandling af cerebral glioma tumor - Google Patents
Fremgangsmde til behandling af cerebral glioma tumorInfo
- Publication number
- DK2044026T3 DK2044026T3 DK07719115.3T DK07719115T DK2044026T3 DK 2044026 T3 DK2044026 T3 DK 2044026T3 DK 07719115 T DK07719115 T DK 07719115T DK 2044026 T3 DK2044026 T3 DK 2044026T3
- Authority
- DK
- Denmark
- Prior art keywords
- procedures
- treatment
- glioma tumor
- cerebral glioma
- cerebral
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81577906P | 2006-06-22 | 2006-06-22 | |
PCT/AU2007/000876 WO2007147217A1 (en) | 2006-06-22 | 2007-06-22 | Method of treatment of glioma brain tumour |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2044026T3 true DK2044026T3 (da) | 2014-06-30 |
Family
ID=38833006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07719115.3T DK2044026T3 (da) | 2006-06-22 | 2007-06-22 | Fremgangsmde til behandling af cerebral glioma tumor |
Country Status (9)
Country | Link |
---|---|
US (1) | US8163760B2 (da) |
EP (1) | EP2044026B1 (da) |
JP (1) | JP5415942B2 (da) |
CN (1) | CN101589026B (da) |
AU (1) | AU2007262670B2 (da) |
CA (1) | CA2656825C (da) |
DK (1) | DK2044026T3 (da) |
ES (1) | ES2474865T3 (da) |
WO (1) | WO2007147217A1 (da) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
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AU2002950217A0 (en) | 2002-07-16 | 2002-09-12 | Prana Biotechnology Limited | 8- Hydroxy Quinoline Derivatives |
WO2007118276A1 (en) * | 2006-04-14 | 2007-10-25 | Prana Biotechnology Ltd | Method of treatment of age-related macular degeneration(amd) |
JP5419706B2 (ja) * | 2006-12-20 | 2014-02-19 | タケダ カリフォルニア インコーポレイテッド | グルコキナーゼアクチベーター |
US9321730B2 (en) | 2007-08-21 | 2016-04-26 | The Hong Kong Polytechnic University | Method of making and administering quinoline derivatives as anti-cancer agents |
KR20100116206A (ko) | 2008-02-01 | 2010-10-29 | 다케다 야쿠힌 고교 가부시키가이샤 | Hsp90 저해제로서의 옥심 유도체 |
GB0806794D0 (en) * | 2008-04-15 | 2008-05-14 | Ludwig Inst Cancer Res | Therapeutic compounds |
CA2737219C (en) * | 2008-08-11 | 2017-02-28 | Tracy Keller | Halofuginone analogs for inhibition of trna synthetases and uses thereof |
DK2379510T3 (da) * | 2008-12-24 | 2016-12-19 | Prana Biotechnology Ltd | Quinazolinonforbindelser |
US10253020B2 (en) | 2009-06-12 | 2019-04-09 | Abivax | Compounds for preventing, inhibiting, or treating cancer, AIDS and/or premature aging |
CN102603628B (zh) * | 2010-12-22 | 2016-08-17 | 香港理工大学 | 作为抗癌试剂的喹啉衍生物 |
WO2012088266A2 (en) | 2010-12-22 | 2012-06-28 | Incyte Corporation | Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3 |
EP2565186A1 (en) * | 2011-09-02 | 2013-03-06 | Hybrigenics S.A. | Selective and reversible inhibitors of ubiquitin specific protease 7 |
FR2984317B1 (fr) * | 2011-12-20 | 2015-02-27 | Univ Rennes | Composes chelateurs de metal presentant au moins une chaine polyaminee. |
EP2802572B1 (en) | 2012-01-13 | 2018-11-07 | President and Fellows of Harvard College | Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions |
CN107383009B (zh) | 2012-06-13 | 2020-06-09 | 因塞特控股公司 | 作为fgfr抑制剂的取代的三环化合物 |
WO2014026125A1 (en) | 2012-08-10 | 2014-02-13 | Incyte Corporation | Pyrazine derivatives as fgfr inhibitors |
US9266892B2 (en) | 2012-12-19 | 2016-02-23 | Incyte Holdings Corporation | Fused pyrazoles as FGFR inhibitors |
JP6027267B2 (ja) * | 2012-12-27 | 2016-11-16 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Comt阻害剤 |
EP2757161A1 (en) | 2013-01-17 | 2014-07-23 | Splicos | miRNA-124 as a biomarker of viral infection |
SG11201508328PA (en) | 2013-04-19 | 2015-11-27 | Incyte Corp | Bicyclic heterocycles as fgfr inhibitors |
CN105829285A (zh) | 2013-10-23 | 2016-08-03 | 中外制药株式会社 | 喹唑啉酮和异喹啉酮衍生物 |
EP2974729A1 (en) | 2014-07-17 | 2016-01-20 | Abivax | Quinoline derivatives for use in the treatment of inflammatory diseases |
US10851105B2 (en) | 2014-10-22 | 2020-12-01 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
CN107001360B (zh) | 2014-12-02 | 2020-09-18 | 普拉纳生物技术有限公司 | 4H-吡啶并[1,2-a]嘧啶-4-酮化合物 |
MA41551A (fr) | 2015-02-20 | 2017-12-26 | Incyte Corp | Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4 |
WO2016134294A1 (en) | 2015-02-20 | 2016-08-25 | Incyte Corporation | Bicyclic heterocycles as fgfr4 inhibitors |
CN107438607B (zh) | 2015-02-20 | 2021-02-05 | 因赛特公司 | 作为fgfr抑制剂的双环杂环 |
TW201815787A (zh) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
TW201825465A (zh) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
TW201813963A (zh) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
AR111960A1 (es) | 2017-05-26 | 2019-09-04 | Incyte Corp | Formas cristalinas de un inhibidor de fgfr y procesos para su preparación |
WO2019067503A1 (en) * | 2017-09-26 | 2019-04-04 | Dana-Farber Cancer Institute, Inc. | NEW USP7 INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA |
AU2019262195B2 (en) | 2018-05-04 | 2024-09-12 | Incyte Corporation | Solid forms of an FGFR inhibitor and processes for preparing the same |
CA3099116A1 (en) | 2018-05-04 | 2019-11-07 | Incyte Corporation | Salts of an fgfr inhibitor |
US11708353B2 (en) | 2018-06-08 | 2023-07-25 | The General Hospital Corporation | Inhibitors of prolyl-tRNA-synthetase |
EP3669873A1 (en) | 2018-12-20 | 2020-06-24 | Abivax | Quinoline derivatives for use ine the traeatment of inflammation diseases |
CN111471012B (zh) * | 2019-01-23 | 2023-04-25 | 鲁南制药集团股份有限公司 | 一种蜈蚣喹啉类化合物、制备方法及其应用 |
US11628162B2 (en) | 2019-03-08 | 2023-04-18 | Incyte Corporation | Methods of treating cancer with an FGFR inhibitor |
WO2021007269A1 (en) | 2019-07-09 | 2021-01-14 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
CN110240590A (zh) * | 2019-07-16 | 2019-09-17 | 广州新民培林医药科技有限公司 | 一类嘧啶喹啉衍生物及其制备方法和应用 |
JP2022552324A (ja) | 2019-10-14 | 2022-12-15 | インサイト・コーポレイション | Fgfr阻害剤としての二環式複素環 |
US11566028B2 (en) | 2019-10-16 | 2023-01-31 | Incyte Corporation | Bicyclic heterocycles as FGFR inhibitors |
US20230116403A1 (en) | 2019-12-02 | 2023-04-13 | Storm Therapeutics Limited | Polyheterocyclic compounds as mettl3 inhibitors |
CA3163875A1 (en) | 2019-12-04 | 2021-06-10 | Incyte Corporation | Tricyclic heterocycles as fgfr inhibitors |
KR20220131900A (ko) | 2019-12-04 | 2022-09-29 | 인사이트 코포레이션 | Fgfr 억제제의 유도체 |
WO2021146424A1 (en) | 2020-01-15 | 2021-07-22 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
US11753413B2 (en) | 2020-06-19 | 2023-09-12 | Incyte Corporation | Substituted pyrrolo[2,1-f][1,2,4]triazine compounds as JAK2 V617F inhibitors |
US11691971B2 (en) | 2020-06-19 | 2023-07-04 | Incyte Corporation | Naphthyridinone compounds as JAK2 V617F inhibitors |
TW202216713A (zh) | 2020-07-02 | 2022-05-01 | 美商英塞特公司 | 作為jak2 v617f抑制劑之三環脲化合物 |
US11767323B2 (en) | 2020-07-02 | 2023-09-26 | Incyte Corporation | Tricyclic pyridone compounds as JAK2 V617F inhibitors |
WO2022046989A1 (en) | 2020-08-27 | 2022-03-03 | Incyte Corporation | Tricyclic urea compounds as jak2 v617f inhibitors |
WO2022140231A1 (en) | 2020-12-21 | 2022-06-30 | Incyte Corporation | Deazaguaine compounds as jak2 v617f inhibitors |
US11958861B2 (en) | 2021-02-25 | 2024-04-16 | Incyte Corporation | Spirocyclic lactams as JAK2 V617F inhibitors |
US12065494B2 (en) | 2021-04-12 | 2024-08-20 | Incyte Corporation | Combination therapy comprising an FGFR inhibitor and a Nectin-4 targeting agent |
CN113214249B (zh) * | 2021-04-23 | 2023-09-19 | 成都大学 | 吡啶并[1,2-a]嘧啶-4-硫酮化合物的合成方法 |
JP2024522189A (ja) | 2021-06-09 | 2024-06-11 | インサイト・コーポレイション | Fgfr阻害剤としての三環式ヘテロ環 |
WO2023078252A1 (en) | 2021-11-02 | 2023-05-11 | Flare Therapeutics Inc. | Pparg inverse agonists and uses thereof |
TW202337453A (zh) | 2022-03-17 | 2023-10-01 | 美商英塞特公司 | 作為jak2 v617f抑制劑之三環脲化合物 |
CN116410132B (zh) * | 2023-02-23 | 2024-07-09 | 广东工业大学 | 一种8-羟基喹啉类化合物及其制备方法和在制备抗肿瘤药物上的应用 |
Family Cites Families (12)
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ES2265923T3 (es) | 1999-03-24 | 2007-03-01 | Anormed Inc. | Compuestos heterociclicos que se unen a receptores de quimiocinas. |
NZ520300A (en) * | 2000-01-24 | 2004-05-28 | Kinacia Pty Ltd | Morpholino-substituted pyridopyrimidine, quinolone and benzopyranone derivatives that inhibit the enzyme phosphoinositide (PI) 3-kinase |
AU2002230056A1 (en) * | 2001-01-29 | 2002-08-12 | Insight Strategy And Marketing Ltd | Indole derivatives and their uses as heparanase inhibitors |
KR20040004705A (ko) * | 2001-06-08 | 2004-01-13 | 시토비아 인크. | 카스파제의 활성제 및 아폽토시스의 유도제로서의 치환된3-아릴-5-아릴-[1,2,4]-옥사디아졸과 유사체 및 이의 용도 |
EP1478646A1 (en) | 2002-02-20 | 2004-11-24 | PHARMACIA & UPJOHN COMPANY | Azabicyclic compounds with alfa7 nicotinic acetylcholine receptor activity |
AU2003282726B2 (en) | 2002-10-03 | 2010-10-07 | Targegen, Inc. | Vasculostatic agents and methods of use thereof |
WO2004031161A1 (en) * | 2002-10-04 | 2004-04-15 | Prana Biotechnology Limited | Neurologically-active compounds |
WO2005063213A1 (en) | 2003-12-19 | 2005-07-14 | Biodelivery Sciences International, Inc. | Rigid liposomal cochleate and methods of use and manufacture |
WO2006031806A2 (en) | 2004-09-10 | 2006-03-23 | Atherogenics, Inc. | 2-thiopyrimidinones as therapeutic agents |
JP5144532B2 (ja) * | 2005-11-30 | 2013-02-13 | バーテックス ファーマシューティカルズ インコーポレイテッド | c−Met阻害剤及び用法 |
DE102005059479A1 (de) | 2005-12-13 | 2007-06-14 | Merck Patent Gmbh | Hydroxychinolinderivate |
WO2007118276A1 (en) * | 2006-04-14 | 2007-10-25 | Prana Biotechnology Ltd | Method of treatment of age-related macular degeneration(amd) |
-
2007
- 2007-06-22 EP EP07719115.3A patent/EP2044026B1/en not_active Not-in-force
- 2007-06-22 CN CN2007800311672A patent/CN101589026B/zh not_active Expired - Fee Related
- 2007-06-22 ES ES07719115.3T patent/ES2474865T3/es active Active
- 2007-06-22 US US12/306,202 patent/US8163760B2/en not_active Expired - Fee Related
- 2007-06-22 CA CA2656825A patent/CA2656825C/en not_active Expired - Fee Related
- 2007-06-22 AU AU2007262670A patent/AU2007262670B2/en not_active Ceased
- 2007-06-22 WO PCT/AU2007/000876 patent/WO2007147217A1/en active Application Filing
- 2007-06-22 JP JP2009515675A patent/JP5415942B2/ja not_active Expired - Fee Related
- 2007-06-22 DK DK07719115.3T patent/DK2044026T3/da active
Also Published As
Publication number | Publication date |
---|---|
EP2044026A4 (en) | 2009-08-05 |
WO2007147217A1 (en) | 2007-12-27 |
JP5415942B2 (ja) | 2014-02-12 |
CN101589026A (zh) | 2009-11-25 |
US20100069393A1 (en) | 2010-03-18 |
EP2044026A1 (en) | 2009-04-08 |
JP2009541223A (ja) | 2009-11-26 |
AU2007262670A1 (en) | 2007-12-27 |
CN101589026B (zh) | 2013-10-16 |
EP2044026B1 (en) | 2014-03-26 |
AU2007262670A2 (en) | 2009-03-26 |
US8163760B2 (en) | 2012-04-24 |
CA2656825C (en) | 2013-12-10 |
ES2474865T3 (es) | 2014-07-09 |
CA2656825A1 (en) | 2007-12-27 |
AU2007262670B2 (en) | 2012-12-20 |
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