FR2926297B1 - Molecules chimiques inhibitrices du mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage. - Google Patents

Molecules chimiques inhibitrices du mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage.

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Publication number
FR2926297B1
FR2926297B1 FR0850144A FR0850144A FR2926297B1 FR 2926297 B1 FR2926297 B1 FR 2926297B1 FR 0850144 A FR0850144 A FR 0850144A FR 0850144 A FR0850144 A FR 0850144A FR 2926297 B1 FR2926297 B1 FR 2926297B1
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FR
France
Prior art keywords
splice
anomalies
treating diseases
diseases resulting
chemical molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR0850144A
Other languages
English (en)
Other versions
FR2926297A1 (fr
Inventor
Jamal Tazi
David Grierson
Betzer Florence Mahuteau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut Curie
Universite de Montpellier
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority to FR0850144A priority Critical patent/FR2926297B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to DK09700499.8T priority patent/DK2235000T3/da
Priority to ES19164367T priority patent/ES2934810T3/es
Priority to CA2946326A priority patent/CA2946326C/fr
Priority to PCT/EP2009/050280 priority patent/WO2009087238A2/fr
Priority to JP2010541800A priority patent/JP5784909B2/ja
Priority to CA3072245A priority patent/CA3072245C/fr
Priority to CN201410299552.7A priority patent/CN104086482B/zh
Priority to ES09700499T priority patent/ES2816178T3/es
Priority to PT97004998T priority patent/PT2235000T/pt
Priority to EP09700499.8A priority patent/EP2235000B1/fr
Priority to CN201410301260.2A priority patent/CN104130242B/zh
Priority to PL09700499T priority patent/PL2235000T3/pl
Priority to CA2946329A priority patent/CA2946329C/fr
Priority to US12/811,931 priority patent/US8604063B2/en
Priority to CN200980106361.1A priority patent/CN101965341B/zh
Priority to CA2946336A priority patent/CA2946336C/fr
Priority to CA2711652A priority patent/CA2711652C/fr
Priority to EP19164367.5A priority patent/EP3536691B1/fr
Publication of FR2926297A1 publication Critical patent/FR2926297A1/fr
Priority to FR1350600A priority patent/FR2983196B1/fr
Priority to FR1350599A priority patent/FR2983199B1/fr
Priority to FR1350601A priority patent/FR2983200B1/fr
Publication of FR2926297B1 publication Critical patent/FR2926297B1/fr
Application granted granted Critical
Priority to US14/070,799 priority patent/US9233931B2/en
Priority to US14/958,602 priority patent/US10130595B2/en
Priority to US16/153,249 priority patent/US10654813B2/en
Priority to HRP20201369TT priority patent/HRP20201369T1/hr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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FR0850144A 2008-01-10 2008-01-10 Molecules chimiques inhibitrices du mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage. Active FR2926297B1 (fr)

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FR0850144A FR2926297B1 (fr) 2008-01-10 2008-01-10 Molecules chimiques inhibitrices du mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage.
CA2946336A CA2946336C (fr) 2008-01-10 2009-01-12 Molecules chimiques inhibant le mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage
ES19164367T ES2934810T3 (es) 2008-01-10 2009-01-12 Moléculas químicas que inhiben el mecanismo de empalme para tratar enfermedades causadas por anomalías de empalme
PCT/EP2009/050280 WO2009087238A2 (fr) 2008-01-10 2009-01-12 Molécules chimiques inhibant le mécanisme d'épissage pour traiter des maladies résultant d'anomalies d'épissage
JP2010541800A JP5784909B2 (ja) 2008-01-10 2009-01-12 スプライシング異常からもたらされる疾患を処置する為のスライスする機構を阻害する化学分子
CA3072245A CA3072245C (fr) 2008-01-10 2009-01-12 Molecules chimiques inhibant le mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage
CN201410299552.7A CN104086482B (zh) 2008-01-10 2009-01-12 用于治疗由剪接异常引起的疾病的抑制剪接机理的化学分子
ES09700499T ES2816178T3 (es) 2008-01-10 2009-01-12 Moléculas químicas que inhiben el mecanismo de corte para tratar enfermedades causadas por anomalías de empalme
PT97004998T PT2235000T (pt) 2008-01-10 2009-01-12 Moléculas químicas que inibem o mecanismo de corte para o tratamento de doenças resultantes de anomalias de splicing
EP09700499.8A EP2235000B1 (fr) 2008-01-10 2009-01-12 Molécules chimiques inhibant le mécanisme d'épissage pour traiter des maladies résultant d'anomalies d'épissage
CN201410301260.2A CN104130242B (zh) 2008-01-10 2009-01-12 用于治疗由剪接异常引起的疾病的抑制剪接机理的化学分子
PL09700499T PL2235000T3 (pl) 2008-01-10 2009-01-12 Cząsteczki chemiczne hamujące mechanizm splicingu do leczenia chorób wynikających z nieprawidłowości splicingu
CA2946329A CA2946329C (fr) 2008-01-10 2009-01-12 Molecules chimiques inhibant le mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage
US12/811,931 US8604063B2 (en) 2008-01-10 2009-01-12 Chemical molecules that inhibit the slicing mechanism for treating diseases resulting from splicing anomalies
DK09700499.8T DK2235000T3 (da) 2008-01-10 2009-01-12 Kemiske molekyler, der hæmmer splejsningsmekanismen, til behandling af sygdomme, der skyldes splejsningsanomalier
CA2946326A CA2946326C (fr) 2008-01-10 2009-01-12 Molecules chimiques inhibant le mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage
CA2711652A CA2711652C (fr) 2008-01-10 2009-01-12 Molecules chimiques inhibant le mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage
EP19164367.5A EP3536691B1 (fr) 2008-01-10 2009-01-12 Molécules chimiques inhibant le mécanisme d'épissage pour traiter des maladies résultant d'anomalies d'épissage
CN200980106361.1A CN101965341B (zh) 2008-01-10 2009-01-12 用于治疗由剪接异常引起的疾病的抑制剪接机理的化学分子
FR1350600A FR2983196B1 (fr) 2008-01-10 2013-01-24 Molecules chimiques inhibitrices du mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage.
FR1350599A FR2983199B1 (fr) 2008-01-10 2013-01-24 Molecules chimiques inhibitrices du mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage.
FR1350601A FR2983200B1 (fr) 2008-01-10 2013-01-24 Molecules chimiques inhibitrices du mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage.
US14/070,799 US9233931B2 (en) 2008-01-10 2013-11-04 Chemical molecules that inhibit the slicing mechanism for treating diseases resulting from splicing anomalies
US14/958,602 US10130595B2 (en) 2008-01-10 2015-12-03 Chemical molecules that inhibit the slicing mechanism for treating diseases resulting from splicing anomalies
US16/153,249 US10654813B2 (en) 2008-01-10 2018-10-05 Chemical molecules that inhibit the slicing mechanism for treating diseases resulting from splicing anomalies
HRP20201369TT HRP20201369T1 (hr) 2008-01-10 2020-08-28 Kemijske molekule koje inhibiraju mehanizam prekrajanja za lječenje bolesti koje proizlaze iz anomalija prekrajanja

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FR1350600A Active FR2983196B1 (fr) 2008-01-10 2013-01-24 Molecules chimiques inhibitrices du mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage.
FR1350599A Active FR2983199B1 (fr) 2008-01-10 2013-01-24 Molecules chimiques inhibitrices du mecanisme d'epissage pour traiter des maladies resultant d'anomalies d'epissage.
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JP5784909B2 (ja) 2015-09-24
DK2235000T3 (da) 2020-09-07
WO2009087238A9 (fr) 2010-02-25
US20110053975A1 (en) 2011-03-03
CN101965341B (zh) 2014-07-16
FR2983196A1 (fr) 2013-05-31
CA2946326C (fr) 2019-02-19
FR2983200B1 (fr) 2015-09-25
US20190022037A1 (en) 2019-01-24
WO2009087238A3 (fr) 2010-09-16
US20160166519A1 (en) 2016-06-16
WO2009087238A2 (fr) 2009-07-16
CA2711652C (fr) 2016-12-06
US10654813B2 (en) 2020-05-19
CN104130242B (zh) 2016-10-05
FR2926297A1 (fr) 2009-07-17
CN104086482B (zh) 2017-10-13
EP2235000A2 (fr) 2010-10-06
FR2983199B1 (fr) 2015-09-25
CA3072245C (fr) 2022-10-04
FR2983199A1 (fr) 2013-05-31
CA2946336A1 (fr) 2009-07-16
PL2235000T3 (pl) 2021-05-17
US20140155436A1 (en) 2014-06-05
EP3536691B1 (fr) 2022-10-05
EP3536691A1 (fr) 2019-09-11
FR2983200A1 (fr) 2013-05-31
CN104086482A (zh) 2014-10-08
CA2946329A1 (fr) 2009-07-16
ES2934810T3 (es) 2023-02-27
CN101965341A (zh) 2011-02-02
CA3072245A1 (fr) 2009-07-16
ES2816178T3 (es) 2021-03-31
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US8604063B2 (en) 2013-12-10
CA2946326A1 (fr) 2009-07-16
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CA2711652A1 (fr) 2009-07-16
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CA2946336C (fr) 2019-02-19
US10130595B2 (en) 2018-11-20
US9233931B2 (en) 2016-01-12
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EP2235000B1 (fr) 2020-06-17
FR2983196B1 (fr) 2015-12-11

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