DK2235000T3 - Kemiske molekyler, der hæmmer splejsningsmekanismen, til behandling af sygdomme, der skyldes splejsningsanomalier - Google Patents

Kemiske molekyler, der hæmmer splejsningsmekanismen, til behandling af sygdomme, der skyldes splejsningsanomalier Download PDF

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DK2235000T3
DK2235000T3 DK09700499.8T DK09700499T DK2235000T3 DK 2235000 T3 DK2235000 T3 DK 2235000T3 DK 09700499 T DK09700499 T DK 09700499T DK 2235000 T3 DK2235000 T3 DK 2235000T3
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splicing
treatment
diseases caused
anomalies
chemical molecules
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DK09700499.8T
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Jamal Tazi
David Grierson
Florence Mahuteau-Betzer
Pierre Roux
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Inst Curie
Univ Montpellier
Centre Nat Rech Scient
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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DK09700499.8T 2008-01-10 2009-01-12 Kemiske molekyler, der hæmmer splejsningsmekanismen, til behandling af sygdomme, der skyldes splejsningsanomalier DK2235000T3 (da)

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FR2926297B1 (fr) 2013-03-08
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HRP20201369T1 (hr) 2020-11-27
FR2983200B1 (fr) 2015-09-25
EP3536691A1 (en) 2019-09-11
US10130595B2 (en) 2018-11-20
FR2983200A1 (fr) 2013-05-31
WO2009087238A3 (en) 2010-09-16
CA3072245A1 (en) 2009-07-16
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US8604063B2 (en) 2013-12-10
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ES2816178T3 (es) 2021-03-31
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US20160166519A1 (en) 2016-06-16
FR2983196A1 (fr) 2013-05-31
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FR2983196B1 (fr) 2015-12-11
WO2009087238A9 (en) 2010-02-25
CN101965341A (zh) 2011-02-02
EP2235000B1 (en) 2020-06-17
FR2926297A1 (fr) 2009-07-17
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