ATE514679T1 - Biarylcarboxyarylamide als modulatoren des vanilloid-1-rezeptors - Google Patents

Biarylcarboxyarylamide als modulatoren des vanilloid-1-rezeptors

Info

Publication number
ATE514679T1
ATE514679T1 AT07764992T AT07764992T ATE514679T1 AT E514679 T1 ATE514679 T1 AT E514679T1 AT 07764992 T AT07764992 T AT 07764992T AT 07764992 T AT07764992 T AT 07764992T AT E514679 T1 ATE514679 T1 AT E514679T1
Authority
AT
Austria
Prior art keywords
biarylcarboxyarylamide
vanilloid
modulators
receptor
derivatives
Prior art date
Application number
AT07764992T
Other languages
English (en)
Inventor
Pier Baraldi
Pier Borea
Pierangelo Geppetti
Maria Pavani
Francesca Fruttarolo
Marcello Trevisani
Original Assignee
Pharmeste Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmeste Srl filed Critical Pharmeste Srl
Application granted granted Critical
Publication of ATE514679T1 publication Critical patent/ATE514679T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
AT07764992T 2006-07-10 2007-07-02 Biarylcarboxyarylamide als modulatoren des vanilloid-1-rezeptors ATE514679T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06014302A EP1889830A1 (de) 2006-07-10 2006-07-10 Biarylcarboxyarylamide als Vanilloid-1 Rezeptor Modulatoren
PCT/EP2007/005835 WO2008006480A1 (en) 2006-07-10 2007-07-02 Biarylcarboxyarylamides as vanilloid-1 receptor modulators

Publications (1)

Publication Number Publication Date
ATE514679T1 true ATE514679T1 (de) 2011-07-15

Family

ID=37433925

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07764992T ATE514679T1 (de) 2006-07-10 2007-07-02 Biarylcarboxyarylamide als modulatoren des vanilloid-1-rezeptors

Country Status (11)

Country Link
US (1) US8222275B2 (de)
EP (2) EP1889830A1 (de)
JP (1) JP5166412B2 (de)
CN (1) CN101490006B (de)
AT (1) ATE514679T1 (de)
BR (1) BRPI0713988A2 (de)
CA (1) CA2657300A1 (de)
ES (1) ES2366240T3 (de)
MX (1) MX2009000366A (de)
RU (1) RU2468020C2 (de)
WO (1) WO2008006480A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2048133A1 (de) * 2007-10-04 2009-04-15 Pharmeste S.r.l. Nicotinamid-N-oxid-Derivate als Modulatoren des Vanilloid-1-Rezeptors
CN107522669B (zh) * 2017-08-24 2019-12-03 重庆美莱德生物医药有限公司 瞬时受体电位香草酸亚型1拮抗剂及其制备方法和用途
CN107522668B (zh) * 2017-08-24 2019-12-03 重庆医科大学 Trpv1拮抗剂及其制备方法和用途
RU2755206C1 (ru) 2020-05-20 2021-09-14 Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) Средство пролонгированного анальгетического действия и лекарственный препарат на его основе

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20030417A1 (es) * 2001-09-13 2003-08-06 Smithkline Beecham Plc Derivados de urea como antagonistas del receptor vainilloide
CA2458266C (en) 2001-09-18 2011-03-15 F. Hoffmann-La Roche Ag Substituted urea retinoid agonists ii
CA2468544A1 (en) 2001-12-10 2003-06-19 Amgen Inc. Vanilloid receptor ligands
TWI319387B (en) * 2002-04-05 2010-01-11 Astrazeneca Ab Benzamide derivatives
WO2004056774A2 (en) * 2002-12-19 2004-07-08 Neurogen Corporation Substituted biphenyl-4-carboxylic acid arylamide analogues as capsaicin receptor modulators
EP1889837A1 (de) * 2006-07-10 2008-02-20 Pharmeste S.r.l. VR1 Vanilloidrezeptorantagonisten mit jononischen Substrukturen

Also Published As

Publication number Publication date
ES2366240T3 (es) 2011-10-18
RU2468020C2 (ru) 2012-11-27
EP1889830A1 (de) 2008-02-20
BRPI0713988A2 (pt) 2012-11-20
EP2041094A1 (de) 2009-04-01
JP5166412B2 (ja) 2013-03-21
US8222275B2 (en) 2012-07-17
EP2041094B1 (de) 2011-06-29
CA2657300A1 (en) 2008-01-17
MX2009000366A (es) 2009-03-09
JP2009542738A (ja) 2009-12-03
RU2008152764A (ru) 2010-07-20
CN101490006A (zh) 2009-07-22
US20100081687A1 (en) 2010-04-01
CN101490006B (zh) 2012-05-23
WO2008006480A1 (en) 2008-01-17

Similar Documents

Publication Publication Date Title
EA201170521A1 (ru) Новые соединения
UA102251C2 (ru) Производные аминодигидротиазина как ингибиторы васе для лечения болезни альцгеймера
EA200801428A1 (ru) Производные пиридиазинона для лечения опухолей
EA201170252A1 (ru) Амидофеноксиндазолы в качестве ингибиторов c-мет
ATE516286T1 (de) 5-(ä1,3,4üoxadiazol-2-yl)-1h-indazol und 5-(ä1,3, 4üthiadiazol-2-yl)-1h-indazol derivate als sgk- inhibitoren zur behandlung von diabetes
EA200802213A1 (ru) Способы лечения заболеваний крови
ATE548374T1 (de) 2'-fluor-2'-desoxytetrahydrouridine als cytidindeaminaseinhibitoren
NO20083002L (no) Fremgangsmate for anvendelse av CD40-bindende forbindelser
CY1113924T1 (el) Ενωσεις καρβαζολης και θεραπευτικες χρησεις των ενωσεων
TN2011000279A1 (en) Novel pyrazole -4-n-alkoxycarboxamides as microbiocides
EA201170832A1 (ru) Пуриновые соединения
MY153915A (en) Organic compounds
NO20083153L (no) Kjemiske forbindelser
EA201171081A1 (ru) Производные индола в качестве антагонистов рецептора crth2
DK2026803T3 (da) Sammensætninger af R(+) og S(-) pramipexol og fremgangsmåder til anvendelse heraf
EA201000895A1 (ru) Композиции и способы для лечения лизосомных болезней
UA103625C2 (en) 5-hetrocyclylalkyl-3-hydroxy-2-phenylcyclopent-2-enons as herbicides
BRPI0509660A (pt) compostos de beta-carbolina de utilidade no tratamento de doenças inflamatórias
BRPI0814772A2 (pt) Indazóis substituídos por 5-piridinona
WO2007097981A3 (en) Alpha carbolines and uses thereof
ATE459620T1 (de) Benzimidazolthiophenverbindungen als plk- modulatoren
UA106880C2 (uk) Нові гербіциди
MY147649A (en) Benzimidazole derivatives useful in treatment of vallinoid receptor trpv1 related disorders
EA201000550A1 (ru) Производные тиазола
MX2010006206A (es) Derivados de oxindol substituidos por 5-halogeno y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties