ATE514679T1 - Biarylcarboxyarylamide als modulatoren des vanilloid-1-rezeptors - Google Patents
Biarylcarboxyarylamide als modulatoren des vanilloid-1-rezeptorsInfo
- Publication number
- ATE514679T1 ATE514679T1 AT07764992T AT07764992T ATE514679T1 AT E514679 T1 ATE514679 T1 AT E514679T1 AT 07764992 T AT07764992 T AT 07764992T AT 07764992 T AT07764992 T AT 07764992T AT E514679 T1 ATE514679 T1 AT E514679T1
- Authority
- AT
- Austria
- Prior art keywords
- biarylcarboxyarylamide
- vanilloid
- modulators
- receptor
- derivatives
- Prior art date
Links
- 108010025083 TRPV1 receptor Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06014302A EP1889830A1 (de) | 2006-07-10 | 2006-07-10 | Biarylcarboxyarylamide als Vanilloid-1 Rezeptor Modulatoren |
PCT/EP2007/005835 WO2008006480A1 (en) | 2006-07-10 | 2007-07-02 | Biarylcarboxyarylamides as vanilloid-1 receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE514679T1 true ATE514679T1 (de) | 2011-07-15 |
Family
ID=37433925
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07764992T ATE514679T1 (de) | 2006-07-10 | 2007-07-02 | Biarylcarboxyarylamide als modulatoren des vanilloid-1-rezeptors |
Country Status (11)
Country | Link |
---|---|
US (1) | US8222275B2 (de) |
EP (2) | EP1889830A1 (de) |
JP (1) | JP5166412B2 (de) |
CN (1) | CN101490006B (de) |
AT (1) | ATE514679T1 (de) |
BR (1) | BRPI0713988A2 (de) |
CA (1) | CA2657300A1 (de) |
ES (1) | ES2366240T3 (de) |
MX (1) | MX2009000366A (de) |
RU (1) | RU2468020C2 (de) |
WO (1) | WO2008006480A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2048133A1 (de) * | 2007-10-04 | 2009-04-15 | Pharmeste S.r.l. | Nicotinamid-N-oxid-Derivate als Modulatoren des Vanilloid-1-Rezeptors |
CN107522669B (zh) * | 2017-08-24 | 2019-12-03 | 重庆美莱德生物医药有限公司 | 瞬时受体电位香草酸亚型1拮抗剂及其制备方法和用途 |
CN107522668B (zh) * | 2017-08-24 | 2019-12-03 | 重庆医科大学 | Trpv1拮抗剂及其制备方法和用途 |
RU2755206C1 (ru) | 2020-05-20 | 2021-09-14 | Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) | Средство пролонгированного анальгетического действия и лекарственный препарат на его основе |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20030417A1 (es) * | 2001-09-13 | 2003-08-06 | Smithkline Beecham Plc | Derivados de urea como antagonistas del receptor vainilloide |
CA2458266C (en) | 2001-09-18 | 2011-03-15 | F. Hoffmann-La Roche Ag | Substituted urea retinoid agonists ii |
CA2468544A1 (en) | 2001-12-10 | 2003-06-19 | Amgen Inc. | Vanilloid receptor ligands |
TWI319387B (en) * | 2002-04-05 | 2010-01-11 | Astrazeneca Ab | Benzamide derivatives |
WO2004056774A2 (en) * | 2002-12-19 | 2004-07-08 | Neurogen Corporation | Substituted biphenyl-4-carboxylic acid arylamide analogues as capsaicin receptor modulators |
EP1889837A1 (de) * | 2006-07-10 | 2008-02-20 | Pharmeste S.r.l. | VR1 Vanilloidrezeptorantagonisten mit jononischen Substrukturen |
-
2006
- 2006-07-10 EP EP06014302A patent/EP1889830A1/de not_active Withdrawn
-
2007
- 2007-07-02 CN CN200780025876XA patent/CN101490006B/zh not_active Expired - Fee Related
- 2007-07-02 RU RU2008152764/04A patent/RU2468020C2/ru not_active IP Right Cessation
- 2007-07-02 AT AT07764992T patent/ATE514679T1/de not_active IP Right Cessation
- 2007-07-02 BR BRPI0713988-8A patent/BRPI0713988A2/pt not_active IP Right Cessation
- 2007-07-02 MX MX2009000366A patent/MX2009000366A/es unknown
- 2007-07-02 ES ES07764992T patent/ES2366240T3/es active Active
- 2007-07-02 JP JP2009518747A patent/JP5166412B2/ja not_active Expired - Fee Related
- 2007-07-02 EP EP07764992A patent/EP2041094B1/de active Active
- 2007-07-02 US US12/307,921 patent/US8222275B2/en not_active Expired - Fee Related
- 2007-07-02 CA CA002657300A patent/CA2657300A1/en not_active Abandoned
- 2007-07-02 WO PCT/EP2007/005835 patent/WO2008006480A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
ES2366240T3 (es) | 2011-10-18 |
RU2468020C2 (ru) | 2012-11-27 |
EP1889830A1 (de) | 2008-02-20 |
BRPI0713988A2 (pt) | 2012-11-20 |
EP2041094A1 (de) | 2009-04-01 |
JP5166412B2 (ja) | 2013-03-21 |
US8222275B2 (en) | 2012-07-17 |
EP2041094B1 (de) | 2011-06-29 |
CA2657300A1 (en) | 2008-01-17 |
MX2009000366A (es) | 2009-03-09 |
JP2009542738A (ja) | 2009-12-03 |
RU2008152764A (ru) | 2010-07-20 |
CN101490006A (zh) | 2009-07-22 |
US20100081687A1 (en) | 2010-04-01 |
CN101490006B (zh) | 2012-05-23 |
WO2008006480A1 (en) | 2008-01-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA201170521A1 (ru) | Новые соединения | |
UA102251C2 (ru) | Производные аминодигидротиазина как ингибиторы васе для лечения болезни альцгеймера | |
EA200801428A1 (ru) | Производные пиридиазинона для лечения опухолей | |
EA201170252A1 (ru) | Амидофеноксиндазолы в качестве ингибиторов c-мет | |
ATE516286T1 (de) | 5-(ä1,3,4üoxadiazol-2-yl)-1h-indazol und 5-(ä1,3, 4üthiadiazol-2-yl)-1h-indazol derivate als sgk- inhibitoren zur behandlung von diabetes | |
EA200802213A1 (ru) | Способы лечения заболеваний крови | |
ATE548374T1 (de) | 2'-fluor-2'-desoxytetrahydrouridine als cytidindeaminaseinhibitoren | |
NO20083002L (no) | Fremgangsmate for anvendelse av CD40-bindende forbindelser | |
CY1113924T1 (el) | Ενωσεις καρβαζολης και θεραπευτικες χρησεις των ενωσεων | |
TN2011000279A1 (en) | Novel pyrazole -4-n-alkoxycarboxamides as microbiocides | |
EA201170832A1 (ru) | Пуриновые соединения | |
MY153915A (en) | Organic compounds | |
NO20083153L (no) | Kjemiske forbindelser | |
EA201171081A1 (ru) | Производные индола в качестве антагонистов рецептора crth2 | |
DK2026803T3 (da) | Sammensætninger af R(+) og S(-) pramipexol og fremgangsmåder til anvendelse heraf | |
EA201000895A1 (ru) | Композиции и способы для лечения лизосомных болезней | |
UA103625C2 (en) | 5-hetrocyclylalkyl-3-hydroxy-2-phenylcyclopent-2-enons as herbicides | |
BRPI0509660A (pt) | compostos de beta-carbolina de utilidade no tratamento de doenças inflamatórias | |
BRPI0814772A2 (pt) | Indazóis substituídos por 5-piridinona | |
WO2007097981A3 (en) | Alpha carbolines and uses thereof | |
ATE459620T1 (de) | Benzimidazolthiophenverbindungen als plk- modulatoren | |
UA106880C2 (uk) | Нові гербіциди | |
MY147649A (en) | Benzimidazole derivatives useful in treatment of vallinoid receptor trpv1 related disorders | |
EA201000550A1 (ru) | Производные тиазола | |
MX2010006206A (es) | Derivados de oxindol substituidos por 5-halogeno y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |