UY34347A - Proteínas de función dual para tratar trastornos metabólicos - Google Patents

Proteínas de función dual para tratar trastornos metabólicos

Info

Publication number
UY34347A
UY34347A UY0001034347A UY34347A UY34347A UY 34347 A UY34347 A UY 34347A UY 0001034347 A UY0001034347 A UY 0001034347A UY 34347 A UY34347 A UY 34347A UY 34347 A UY34347 A UY 34347A
Authority
UY
Uruguay
Prior art keywords
metabolic disorders
dual function
treat metabolic
function proteins
proteins
Prior art date
Application number
UY0001034347A
Other languages
English (en)
Inventor
Brian R Boettcher
Shari L Caplan
Douglas S Daniels
Licht Stuart
Stephen Craig Weldon
Hamamatsu Norio
Susan E Cellitti
Bernhard Hubert Geierstanger
Loew Andreas
Original Assignee
Novartis Ag
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47023090&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY34347(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag, Irm Llc filed Critical Novartis Ag
Publication of UY34347A publication Critical patent/UY34347A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factors [FGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Abstract

La presente invención se refiere a la identificación de nuevas proteínas que comprenden el factor de crecimiento de fibroblastos 21 (FGF21) y otros reguladores metabólicos, incluyendo variantes de los mismos, conocidos por mejorar los perfiles metabólicos en sujetos en quienes se administren. También se divulgan métodos para tratar trastornos asociados con el FGF21, trastornos asociados con GLP-1, y trastornos asociados con Exendina-4, incluyendo condiciones metabólicas.
UY0001034347A 2011-09-26 2012-09-25 Proteínas de función dual para tratar trastornos metabólicos UY34347A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161539290P 2011-09-26 2011-09-26

Publications (1)

Publication Number Publication Date
UY34347A true UY34347A (es) 2013-04-30

Family

ID=47023090

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001034347A UY34347A (es) 2011-09-26 2012-09-25 Proteínas de función dual para tratar trastornos metabólicos

Country Status (26)

Country Link
US (2) US9458214B2 (es)
EP (1) EP2764019B1 (es)
JP (1) JP6152380B2 (es)
KR (1) KR102217254B1 (es)
CN (2) CN104024273B (es)
AP (1) AP2014007544A0 (es)
AR (1) AR088165A1 (es)
AU (1) AU2012316132A1 (es)
BR (1) BR112014007086A2 (es)
CA (1) CA2849760A1 (es)
CL (1) CL2014000737A1 (es)
CO (1) CO6920258A2 (es)
CR (1) CR20140141A (es)
CU (1) CU20140035A7 (es)
EA (1) EA201490697A1 (es)
GT (1) GT201400056A (es)
IL (1) IL231647A0 (es)
MA (1) MA35507B1 (es)
MX (1) MX350840B (es)
PE (1) PE20141542A1 (es)
SG (1) SG11201400596QA (es)
TN (1) TN2014000110A1 (es)
TW (1) TW201315742A (es)
UY (1) UY34347A (es)
WO (1) WO2013049234A2 (es)
ZA (1) ZA201401699B (es)

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