ATE110083T1 - Insulinotropes hormon. - Google Patents

Insulinotropes hormon.

Info

Publication number
ATE110083T1
ATE110083T1 AT87903195T AT87903195T ATE110083T1 AT E110083 T1 ATE110083 T1 AT E110083T1 AT 87903195 T AT87903195 T AT 87903195T AT 87903195 T AT87903195 T AT 87903195T AT E110083 T1 ATE110083 T1 AT E110083T1
Authority
AT
Austria
Prior art keywords
insulinotropic hormone
glp
insulinotropic
hormone
glucagon
Prior art date
Application number
AT87903195T
Other languages
English (en)
Inventor
Joel Habener
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25332078&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE110083(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of ATE110083T1 publication Critical patent/ATE110083T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
AT87903195T 1986-05-05 1987-05-05 Insulinotropes hormon. ATE110083T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85992886A 1986-05-05 1986-05-05

Publications (1)

Publication Number Publication Date
ATE110083T1 true ATE110083T1 (de) 1994-09-15

Family

ID=25332078

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87903195T ATE110083T1 (de) 1986-05-05 1987-05-05 Insulinotropes hormon.

Country Status (6)

Country Link
EP (3) EP0587255A1 (de)
JP (1) JP2583257B2 (de)
AT (1) ATE110083T1 (de)
CA (1) CA1341320C (de)
DE (1) DE3750402T3 (de)
WO (1) WO1987006941A1 (de)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0587255A1 (de) 1986-05-05 1994-03-16 The General Hospital Corporation Insulinotropische Hormone
US5614492A (en) * 1986-05-05 1997-03-25 The General Hospital Corporation Insulinotropic hormone GLP-1 (7-36) and uses thereof
US7138486B2 (en) 1986-05-05 2006-11-21 The General Hospital Corporation Insulinotropic hormone derivatives and uses thereof
US6849708B1 (en) 1986-05-05 2005-02-01 The General Hospital Corporation Insulinotropic hormone and uses thereof
JPH04504246A (ja) * 1989-03-20 1992-07-30 ザ・ジェネラル・ホスピタル・コーポレーション インシュリン刺激ホルモン
DK0512042T3 (da) * 1990-01-24 1998-05-11 Douglas I Buckley GLP-1-analoger anvendelige ved diabetesbehandling
US5545618A (en) * 1990-01-24 1996-08-13 Buckley; Douglas I. GLP-1 analogs useful for diabetes treatment
DK36392D0 (da) * 1992-03-19 1992-03-19 Novo Nordisk As Anvendelse af kemisk forbindelse
USRE37302E1 (en) * 1992-03-19 2001-07-31 Novo Nordisk A/S Peptide
US6284727B1 (en) * 1993-04-07 2001-09-04 Scios, Inc. Prolonged delivery of peptides
EP0658568A1 (de) * 1993-12-09 1995-06-21 Eli Lilly And Company Glucagon-ähnliche, insalinotrope Peptide, ihre Zusammensetzungen und ihre Herstellungsverfahren
US5705483A (en) * 1993-12-09 1998-01-06 Eli Lilly And Company Glucagon-like insulinotropic peptides, compositions and methods
US5574008A (en) * 1994-08-30 1996-11-12 Eli Lilly And Company Biologically active fragments of glucagon-like insulinotropic peptide
US5512549A (en) * 1994-10-18 1996-04-30 Eli Lilly And Company Glucagon-like insulinotropic peptide analogs, compositions, and methods of use
DE69529998D1 (de) * 1994-12-23 2003-04-24 Novo Nordisk As Glp-1 zusammensetzungen mit verlängerter wirkdauer
US5990077A (en) * 1995-04-14 1999-11-23 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
US5834428A (en) 1995-04-14 1998-11-10 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
US6184201B1 (en) 1995-04-14 2001-02-06 Nps Allelix Corp. Intestinotrophic glucagon-like peptide-2 analogs
US6268343B1 (en) 1996-08-30 2001-07-31 Novo Nordisk A/S Derivatives of GLP-1 analogs
CA2264243C (en) 1996-08-30 2004-10-05 Novo Nordisk A/S Glp-1 derivatives
US6458924B2 (en) 1996-08-30 2002-10-01 Novo Nordisk A/S Derivatives of GLP-1 analogs
US7235627B2 (en) 1996-08-30 2007-06-26 Novo Nordisk A/S Derivatives of GLP-1 analogs
EP1060191B1 (de) 1998-02-27 2010-04-28 Novo Nordisk A/S Abkömmlinge von glp-1 analogen
DE69942307D1 (de) 1998-02-27 2010-06-10 Novo Nordisk As N-terminal veränderte glp-1 abkömmlinge
WO1999043341A1 (en) * 1998-02-27 1999-09-02 Novo Nordisk A/S Glp-1 derivatives with helix-content exceeding 25 %, forming partially structured micellar-like aggregates
AU3247799A (en) 1998-02-27 1999-09-15 Novo Nordisk A/S Glp-1 derivatives of glp-1 and exendin with protracted profile of action
ATE466026T1 (de) 1998-02-27 2010-05-15 Novo Nordisk As Derivate von glp-1 und exendin mit verlängertem wirkdauer-profil
AU5027299A (en) 1998-07-31 2000-02-28 Novo Nordisk A/S Use of glp-1 and analogues for preventing type ii diabetes
EP2322545A1 (de) 1998-12-07 2011-05-18 Ipsen Pharma GLP-1 Analoge
EP1600162A1 (de) * 1998-12-22 2005-11-30 Eli Lilly & Company Lagerstabile Zusammensetzungen von Glucagon-ähnlichem Peptid-1
JP4689833B2 (ja) * 1998-12-22 2011-05-25 イーライ リリー アンド カンパニー グルカゴン様ペプチド−1の貯蔵安定性製剤
US6927214B1 (en) 1999-01-15 2005-08-09 Novo Nordisk A/S Non-peptide GLP-1 agonists
US6444788B1 (en) 1999-03-15 2002-09-03 Novo Nordisk A/S Ion exchange chromatography of GLP-1, analogs and derivatives thereof
US6451987B1 (en) 1999-03-15 2002-09-17 Novo Nordisk A/S Ion exchange chromatography of proteins and peptides
JP4732590B2 (ja) 1999-03-15 2011-07-27 ノボ ノルディスク アクティーゼルスカブ Glp−1及び近縁ペプチドのイオン交換クロマトグラフィー分離
US6844321B2 (en) 2000-01-31 2005-01-18 Novo Nordisk A/S Crystallization of a GLP-1 analogue
AU2001237254A1 (en) 2000-03-08 2001-09-17 Novo-Nordisk A/S Lowering serum lipids
ES2310192T3 (es) 2000-09-18 2009-01-01 Sanos Bioscience A/S Uso de peptidos glp-2.
EP1346722B1 (de) 2000-12-01 2008-12-10 Takeda Pharmaceutical Company Limited Verfahren zur herstellung einer zubereitung mit einer bioaktiven substanz
EP1351984A2 (de) 2000-12-13 2003-10-15 Eli Lilly And Company Amidiertes glucagonähnliches peptid-1
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
ATE445642T1 (de) 2003-08-21 2009-10-15 Novo Nordisk As Trennung von polypeptiden mit einer racemisierten aminosäure
CA2539253A1 (en) 2003-09-19 2005-03-31 Novo Nordisk A/S Albumin-binding derivatives of therapeutic peptides
RU2421238C2 (ru) 2003-11-20 2011-06-20 Ново Нордиск А/С Пептидная композиция, содержащая пропиленгликоль, являющаяся оптимальной для изготовления и применения в инъекционных устройствах
EP2298337B1 (de) 2003-12-09 2017-02-22 Novo Nordisk A/S Regulierung des bevorzuchtes nahrungsaufnahmen mit verwendung von GLP-1 agonisten
WO2005058252A2 (en) 2003-12-16 2005-06-30 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Glp-1 pharmaceutical compositions
EP1711523B1 (de) 2003-12-16 2012-10-10 Ipsen Pharma Glp-1-analoga
US20050143303A1 (en) 2003-12-26 2005-06-30 Nastech Pharmaceutical Company Inc. Intranasal administration of glucose-regulating peptides
US8410047B2 (en) 2004-06-11 2013-04-02 Novo Nordisk A/S Counteracting drug-induced obesity using GLP-1 agonists
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
SG157423A1 (en) 2004-12-02 2009-12-29 Domantis Ltd Bispecific domain antibodies targeting serum albumin and glp-1 or pyy
EP2573111A1 (de) 2006-04-20 2013-03-27 Amgen Inc. GLP-1-Verbindungen
EP1852108A1 (de) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG Zusammensetzungen von DPP-IV-Inhibitoren
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
EA015687B1 (ru) 2006-05-04 2011-10-31 Бёрингер Ингельхайм Интернациональ Гмбх Полиморфы
PE20091730A1 (es) 2008-04-03 2009-12-10 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
KR20200118243A (ko) 2008-08-06 2020-10-14 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
CN102271775A (zh) 2008-12-08 2011-12-07 诺沃-诺迪斯克有限公司 多肽的逆流提纯
CN107115530A (zh) 2009-11-27 2017-09-01 勃林格殷格翰国际有限公司 基因型糖尿病患者利用dpp‑iv抑制剂例如利拉利汀的治疗
WO2011123943A1 (en) 2010-04-09 2011-10-13 Mount Sinai Hospital Methods for treating disorders of the gastrointestinal tract using a glp-1 agonist
WO2011133948A2 (en) 2010-04-22 2011-10-27 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
AU2011249722B2 (en) 2010-05-05 2015-09-17 Boehringer Ingelheim International Gmbh Combination therapy
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
TW201315742A (zh) 2011-09-26 2013-04-16 Novartis Ag 治療代謝病症之雙功能蛋白質
US20130172244A1 (en) * 2011-12-29 2013-07-04 Thomas Klein Subcutaneous therapeutic use of dpp-4 inhibitor
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
EP2849755A1 (de) 2012-05-14 2015-03-25 Boehringer Ingelheim International GmbH Xanthinderivat als dpp-4-hemmer zur verwendung bei der behandlung von durch podozyten vermittelten erkrankungen und/oder des nephrotischen syndroms
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
US20150157619A1 (en) 2012-07-10 2015-06-11 Takeda Pharmaceutical Company Limited Pharmaceutical preparation for injection
WO2014145718A2 (en) 2013-03-15 2014-09-18 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
WO2015057908A1 (en) 2013-10-18 2015-04-23 Novartis Ag Methods of treating diabetes and related disorders
JP6615109B2 (ja) 2014-02-28 2019-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Dpp−4阻害薬の医学的使用
CA3022202A1 (en) 2016-06-10 2017-12-14 Boehringer Ingelheim International Gmbh Combinations of linagliptin and metformin
KR20200044016A (ko) 2017-08-24 2020-04-28 노보 노르디스크 에이/에스 Glp-1 조성물 및 그 용도
CN109929806B (zh) 2017-12-19 2020-05-08 北京吉源生物科技有限公司 一种表达glp1和fgf21的干细胞及其用途
PE20221575A1 (es) 2020-02-18 2022-10-06 Novo Nordisk As Formulaciones farmaceuticas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK283180A (da) * 1980-07-01 1982-01-02 Novo Industri As Polypeptider og derivater deraf
NZ202757A (en) * 1981-12-23 1985-11-08 Novo Industri As Peptides and medicaments
EP0587255A1 (de) 1986-05-05 1994-03-16 The General Hospital Corporation Insulinotropische Hormone

Also Published As

Publication number Publication date
CA1341320C (en) 2001-11-20
WO1987006941A1 (en) 1987-11-19
DE3750402T3 (de) 1997-04-10
JP2583257B2 (ja) 1997-02-19
EP0305387B1 (de) 1994-08-17
EP0305387A4 (de) 1990-04-10
EP0305387A1 (de) 1989-03-08
EP1498425A1 (de) 2005-01-19
EP0305387B2 (de) 1996-08-28
JPH01502746A (ja) 1989-09-21
DE3750402T2 (de) 1994-12-01
DE3750402D1 (en) 1994-09-22
EP0587255A1 (de) 1994-03-16

Similar Documents

Publication Publication Date Title
ATE110083T1 (de) Insulinotropes hormon.
ATE193541T1 (de) Insulinotropes hormon
DK0699686T3 (da) Biologisk aktive fragmenter af glukagon-lignende insulinotropisk peptid
DK0762890T3 (da) Behandling af diabetes
NO954055D0 (no) Glukogen-liknende insulintropiske peptidanaloger, sammensetninger og fremgangsmåter for anvendelse derav
DE3852636T2 (de) Peptid-analoge vom insulinähnlichen wachstums-faktor 1 (igf-1) oder faktor 2 (igf-2).
ES8609483A1 (es) Un procedimiento para producir un precursor de insulina
AU6286986A (en) Peptide analogues of mammalian insulin-like growth factor-1
GR81550B (de)
AR008269A1 (es) Derivados de insulina con unión a zinc incrementada, un complejo, una composición farmacéutica y proinsulina.
DK0475394T3 (da) Rotte C-type natriuretisk peptid cDNA, og precursorprotein
EP0135720A3 (en) Process for the preparation of insuline derivatives
WO1983002772A1 (en) An improved method for preparing human insulin from non-human insulin
ATE186570T1 (de) Wachstumshormon-releasingfaktor-analoge
FI921855A0 (fi) Superaktiva grf-analoger.
JPS5551045A (en) Preparation of endorphin

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time