US5229272A
(en)
*
|
1989-04-25 |
1993-07-20 |
Igen, Inc. |
Catalytic antibody components
|
WO1990005144A1
(en)
|
1988-11-11 |
1990-05-17 |
Medical Research Council |
Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
JPH03503003A
(ja)
*
|
1988-12-29 |
1991-07-11 |
サイトジェン コーポレーション |
分子認識ユニット
|
US5196510A
(en)
*
|
1988-12-29 |
1993-03-23 |
Cytogen Corporation |
Molecular recognition units
|
US5225538A
(en)
*
|
1989-02-23 |
1993-07-06 |
Genentech, Inc. |
Lymphocyte homing receptor/immunoglobulin fusion proteins
|
US6406697B1
(en)
|
1989-02-23 |
2002-06-18 |
Genentech, Inc. |
Hybrid immunoglobulins
|
US5116964A
(en)
*
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
DE3909799A1
(de)
|
1989-03-24 |
1990-09-27 |
Behringwerke Ag |
Monoklonale antikoerper (mak) gegen tumorassoziierte antigene, ihre herstellung und verwendung
|
US5599538A
(en)
*
|
1989-04-25 |
1997-02-04 |
Igen, Inc. |
Autoantibodies which enhance the rate of a chemical reaction
|
US5236836A
(en)
*
|
1989-04-25 |
1993-08-17 |
Igen, Inc. |
Autoantibodies which enhance the rate of a chemical reaction
|
US5658753A
(en)
*
|
1989-04-25 |
1997-08-19 |
Paul; Sudhir |
Catalytic antibody components
|
US5318897A
(en)
*
|
1989-04-25 |
1994-06-07 |
Igen, Inc. |
Monoclonal antibody and antibody components elicited to a polypeptide antigen ground state
|
US5602015A
(en)
*
|
1989-04-25 |
1997-02-11 |
Igen, Inc. |
Autoantibodies which enhance the rate of a chemical reaction
|
US5194585A
(en)
*
|
1989-04-25 |
1993-03-16 |
Igen, Inc. |
Inhibitors of catalytic antibodies
|
US6048717A
(en)
*
|
1989-04-25 |
2000-04-11 |
Igen International, Inc. |
Inhibitors of catalytic antibodies
|
US6291158B1
(en)
*
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for tapping the immunological repertoire
|
US6969586B1
(en)
|
1989-05-16 |
2005-11-29 |
Scripps Research Institute |
Method for tapping the immunological repertoire
|
US6291160B1
(en)
*
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for producing polymers having a preselected activity
|
CA2016841C
(en)
*
|
1989-05-16 |
1999-09-21 |
William D. Huse |
A method for producing polymers having a preselected activity
|
US6291159B1
(en)
*
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for producing polymers having a preselected activity
|
US6680192B1
(en)
|
1989-05-16 |
2004-01-20 |
Scripps Research Institute |
Method for producing polymers having a preselected activity
|
US6291161B1
(en)
*
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for tapping the immunological repertiore
|
US5231015A
(en)
*
|
1989-10-18 |
1993-07-27 |
Eastman Kodak Company |
Methods of extracting nucleic acids and pcr amplification without using a proteolytic enzyme
|
US6274324B1
(en)
|
1989-12-01 |
2001-08-14 |
Unilever Patent Holdings B.V. |
Specific binding reagent comprising a variable domain protein linked to a support or tracer
|
GB8928501D0
(en)
*
|
1989-12-18 |
1990-02-21 |
Unilever Plc |
Reagents
|
EP0440147B2
(de)
*
|
1990-02-01 |
2014-05-14 |
Siemens Healthcare Diagnostics Products GmbH |
Herstellung und Verwendung von Genbanken menschlicher Antikörper ("Human-Antikörper-Bibliotheken")
|
GB9021671D0
(en)
*
|
1990-10-05 |
1990-11-21 |
Unilever Plc |
Delivery of agents
|
US5427908A
(en)
*
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
US5723286A
(en)
|
1990-06-20 |
1998-03-03 |
Affymax Technologies N.V. |
Peptide library and screening systems
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
US6916605B1
(en)
|
1990-07-10 |
2005-07-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
US7063943B1
(en)
|
1990-07-10 |
2006-06-20 |
Cambridge Antibody Technology |
Methods for producing members of specific binding pairs
|
GB9015198D0
(en)
*
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
GB9206318D0
(en)
*
|
1992-03-24 |
1992-05-06 |
Cambridge Antibody Tech |
Binding substances
|
GB9016299D0
(en)
*
|
1990-07-25 |
1990-09-12 |
Brien Caroline J O |
Binding substances
|
DE4033120A1
(de)
*
|
1990-10-18 |
1992-04-23 |
Boehringer Mannheim Gmbh |
Verfahren zur herstellung von chimaeren antikoerpern
|
US5571894A
(en)
*
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
AU1025692A
(en)
*
|
1991-02-06 |
1992-08-13 |
Ciba-Geigy Ag |
Novel chimeric antiidiotypic monoclonal antibodies
|
JPH05508779A
(ja)
*
|
1991-03-12 |
1993-12-09 |
バイオジェン,インコーポレイテッド |
リンパ球機能関連抗原3のcd2結合ドメイン
|
MX9203138A
(es)
*
|
1991-03-12 |
1992-09-01 |
Biogen Inc |
Dominio de enlace cd2-de antigeno 3 (lfa-3) asociado con funcion linfositos.
|
DE69233367T2
(de)
|
1991-04-10 |
2005-05-25 |
The Scripps Research Institute, La Jolla |
Bibliotheken heterodimerer rezeptoren mittels phagemiden
|
US6492160B1
(en)
|
1991-05-15 |
2002-12-10 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
US6225447B1
(en)
|
1991-05-15 |
2001-05-01 |
Cambridge Antibody Technology Ltd. |
Methods for producing members of specific binding pairs
|
US5871907A
(en)
*
|
1991-05-15 |
1999-02-16 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
US5858657A
(en)
*
|
1992-05-15 |
1999-01-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
US5962255A
(en)
*
|
1992-03-24 |
1999-10-05 |
Cambridge Antibody Technology Limited |
Methods for producing recombinant vectors
|
US6800738B1
(en)
|
1991-06-14 |
2004-10-05 |
Genentech, Inc. |
Method for making humanized antibodies
|
LU91067I2
(fr)
|
1991-06-14 |
2004-04-02 |
Genentech Inc |
Trastuzumab et ses variantes et dérivés immuno chimiques y compris les immotoxines
|
WO1994004679A1
(en)
*
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
US5939531A
(en)
*
|
1991-07-15 |
1999-08-17 |
Novartis Corp. |
Recombinant antibodies specific for a growth factor receptor
|
NL9101290A
(nl)
*
|
1991-07-23 |
1993-02-16 |
Stichting Rega V Z W |
Recombinant dna-molecuul voor de expressie van een fv-fragment van een antilichaam.
|
US6764681B2
(en)
|
1991-10-07 |
2004-07-20 |
Biogen, Inc. |
Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction
|
US5270170A
(en)
*
|
1991-10-16 |
1993-12-14 |
Affymax Technologies N.V. |
Peptide library and screening method
|
US5733731A
(en)
*
|
1991-10-16 |
1998-03-31 |
Affymax Technologies N.V. |
Peptide library and screening method
|
ATE463573T1
(de)
|
1991-12-02 |
2010-04-15 |
Medimmune Ltd |
Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken
|
EP1024191B8
(en)
*
|
1991-12-02 |
2008-11-05 |
Medical Research Council |
Production of anti-self antibodies from antibody segment repertoires and displayed on phage
|
DE4142077A1
(de)
*
|
1991-12-19 |
1993-06-24 |
Boehringer Mannheim Gmbh |
Verfahren zur expression rekombinanter antikoerper
|
US5824307A
(en)
|
1991-12-23 |
1998-10-20 |
Medimmune, Inc. |
Human-murine chimeric antibodies against respiratory syncytial virus
|
US6399368B1
(en)
|
1992-01-17 |
2002-06-04 |
Board Of Regents, The University Of Texas System |
Secretion of T cell receptor fragments from recombinant Escherichia coli cells
|
KR0150060B1
(ko)
|
1992-02-06 |
1998-08-17 |
에릭 에스. 딕커 |
사람 인터루킨-5에 대한 인간화 모노클로날 항체의 고안, 클로닝 및 발현
|
US5733743A
(en)
*
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
EP0640094A1
(en)
*
|
1992-04-24 |
1995-03-01 |
The Board Of Regents, The University Of Texas System |
Recombinant production of immunoglobulin-like domains in prokaryotic cells
|
GB9216983D0
(en)
*
|
1992-08-11 |
1992-09-23 |
Unilever Plc |
Polypeptide production
|
US6765087B1
(en)
|
1992-08-21 |
2004-07-20 |
Vrije Universiteit Brussel |
Immunoglobulins devoid of light chains
|
DE4233152A1
(de)
*
|
1992-10-02 |
1994-04-07 |
Behringwerke Ag |
Antikörper-Enzym-Konjugate zur Prodrug-Aktivierung
|
GB9225453D0
(en)
|
1992-12-04 |
1993-01-27 |
Medical Res Council |
Binding proteins
|
ATE243745T1
(de)
*
|
1994-01-31 |
2003-07-15 |
Univ Boston |
Bibliotheken aus polyklonalen antikörpern
|
US6010861A
(en)
*
|
1994-08-03 |
2000-01-04 |
Dgi Biotechnologies, Llc |
Target specific screens and their use for discovering small organic molecular pharmacophores
|
US6056957A
(en)
*
|
1994-08-04 |
2000-05-02 |
Schering Corporation |
Humanized monoclonal antibodies against human interleukin-5
|
WO1997008320A1
(en)
*
|
1995-08-18 |
1997-03-06 |
Morphosys Gesellschaft Für Proteinoptimierung Mbh |
Protein/(poly)peptide libraries
|
US7264963B1
(en)
|
1995-08-18 |
2007-09-04 |
Morphosys Ag |
Protein(poly)peptide libraries
|
US7368111B2
(en)
|
1995-10-06 |
2008-05-06 |
Cambridge Antibody Technology Limited |
Human antibodies specific for TGFβ2
|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
DE69738254T2
(de)
*
|
1996-05-10 |
2008-08-14 |
Novozymes A/S |
Methode zur bereitstellung von dna sequenzen
|
ATE391183T1
(de)
|
1996-08-19 |
2008-04-15 |
Morphosys Ip Gmbh |
Vektoren/dna-sequenzen aus humanen kombinatorischen antikörper-bibliotheken
|
GB9701425D0
(en)
|
1997-01-24 |
1997-03-12 |
Bioinvent Int Ab |
A method for in vitro molecular evolution of protein function
|
US6670453B2
(en)
|
1997-10-27 |
2003-12-30 |
Unilever Patent Holdings B.V. |
Multivalent antigen-binding proteins
|
EP2189791A3
(en)
|
1998-02-04 |
2011-03-09 |
Life Technologies Corporation |
Microarrays and uses therefor
|
DE69937735T2
(de)
|
1998-05-13 |
2008-11-27 |
Domantis Ltd., Brentford |
Phagen-display-selektionssystem für korrekt gefaltete proteine
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
US6492497B1
(en)
*
|
1999-04-30 |
2002-12-10 |
Cambridge Antibody Technology Limited |
Specific binding members for TGFbeta1
|
US7534605B2
(en)
|
1999-06-08 |
2009-05-19 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
|
US7297478B1
(en)
|
2000-09-22 |
2007-11-20 |
Large Scale Biology Corporation |
Creation of variable length and sequence linker regions for dual-domain or multi-domain molecules
|
US6656467B2
(en)
|
2000-01-27 |
2003-12-02 |
Medimmune, Inc. |
Ultra high affinity neutralizing antibodies
|
AU2001234125A1
(en)
|
2000-02-22 |
2001-09-03 |
Medical And Biological Laboratories Co., Ltd. |
Antibody library
|
EP1259547B1
(en)
|
2000-03-01 |
2012-07-11 |
Medimmune, Inc. |
High potency recombinant antibodies and method for producing them
|
US8288322B2
(en)
|
2000-04-17 |
2012-10-16 |
Dyax Corp. |
Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
|
EP1276855B1
(en)
*
|
2000-04-17 |
2012-10-24 |
Dyax Corp. |
Methods of constructing display libraries of genetic packages for members of a diverse family of peptides
|
EP1176200A3
(de)
|
2000-06-20 |
2005-01-12 |
Switch Biotech Aktiengesellschaft |
Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankung oder Wundheilung sowie ihre Verwendung zur Indentifizierung von pharmakologisch aktiven Substanzen
|
EP2899210A3
(en)
|
2000-06-29 |
2015-11-18 |
Abbvie Inc. |
Dual specificity antibodies and methods of making and using
|
US6902734B2
(en)
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
US7288390B2
(en)
|
2000-08-07 |
2007-10-30 |
Centocor, Inc. |
Anti-dual integrin antibodies, compositions, methods and uses
|
UA81743C2
(uk)
|
2000-08-07 |
2008-02-11 |
Центокор, Инк. |
МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
|
CA2429544C
(en)
|
2000-11-17 |
2010-10-19 |
University Of Rochester |
In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
|
US20050196755A1
(en)
*
|
2000-11-17 |
2005-09-08 |
Maurice Zauderer |
In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
|
US7179900B2
(en)
|
2000-11-28 |
2007-02-20 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
EP1366191A2
(en)
|
2000-12-11 |
2003-12-03 |
Alexion Pharmaceuticals, Inc. |
Nested oligonucleotides containing hairpin for nucleic acid amplification
|
US7658921B2
(en)
|
2000-12-12 |
2010-02-09 |
Medimmune, Llc |
Molecules with extended half-lives, compositions and uses thereof
|
JP4336498B2
(ja)
|
2000-12-12 |
2009-09-30 |
メディミューン,エルエルシー |
延長した半減期を有する分子ならびにその組成物および用途
|
US6958213B2
(en)
|
2000-12-12 |
2005-10-25 |
Alligator Bioscience Ab |
Method for in vitro molecular evolution of protein function
|
CA2784251A1
(en)
|
2000-12-18 |
2002-08-08 |
Dyax Corp. |
Focused libraries of genetic packages
|
US20020086292A1
(en)
|
2000-12-22 |
2002-07-04 |
Shigeaki Harayama |
Synthesis of hybrid polynucleotide molecules using single-stranded polynucleotide molecules
|
WO2002051438A2
(en)
|
2000-12-22 |
2002-07-04 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Use of repulsive guidance molecule (rgm) and its modulators
|
WO2002086096A2
(en)
*
|
2001-01-23 |
2002-10-31 |
University Of Rochester Medical Center |
Methods of producing or identifying intrabodies in eukaryotic cells
|
EP1370292A1
(en)
|
2001-01-31 |
2003-12-17 |
Idec Pharmaceuticals Corporation |
Use of cd23 antagonists for the treatment of neoplastic disorders
|
GB0110029D0
(en)
|
2001-04-24 |
2001-06-13 |
Grosveld Frank |
Transgenic animal
|
US6972324B2
(en)
|
2001-05-18 |
2005-12-06 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Antibodies specific for CD44v6
|
GB0115841D0
(en)
|
2001-06-28 |
2001-08-22 |
Medical Res Council |
Ligand
|
JP4303105B2
(ja)
*
|
2001-06-28 |
2009-07-29 |
ドマンティス リミテッド |
二重特異性リガンドとその利用
|
US20060073141A1
(en)
*
|
2001-06-28 |
2006-04-06 |
Domantis Limited |
Compositions and methods for treating inflammatory disorders
|
EP1419236A4
(en)
|
2001-07-24 |
2005-08-03 |
Biogen Idec Inc |
METHODS OF TREATING OR PREVENTING SCLEROSIS BY USE OF CD2-BINDING AGENTS
|
US6833441B2
(en)
|
2001-08-01 |
2004-12-21 |
Abmaxis, Inc. |
Compositions and methods for generating chimeric heteromultimers
|
EP2281837B1
(en)
|
2001-08-10 |
2016-10-05 |
Aberdeen University |
Antigen binding domains from fish
|
AU2002332598A1
(en)
*
|
2001-08-22 |
2003-03-10 |
Shengfeng Li |
Compositions and methods for generating antigen-binding units
|
WO2003035842A2
(en)
*
|
2001-10-24 |
2003-05-01 |
Dyax Corporation |
Hybridization control of sequence variation
|
US7175983B2
(en)
|
2001-11-02 |
2007-02-13 |
Abmaxis, Inc. |
Adapter-directed display systems
|
GB0126378D0
(en)
|
2001-11-02 |
2002-01-02 |
Oxford Biomedica Ltd |
Antigen
|
AU2002360068B2
(en)
*
|
2001-12-21 |
2009-09-03 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Method for cloning of variable domain sequences
|
US20050069549A1
(en)
|
2002-01-14 |
2005-03-31 |
William Herman |
Targeted ligands
|
EP3031910B1
(en)
|
2002-02-21 |
2017-08-16 |
Institute Of Virology |
Mn/ca ix-specific monoclonal antibodies generated from mn/ca ix-deficient mice and methods of use
|
PL375041A1
(en)
*
|
2002-04-05 |
2005-11-14 |
Amgen Inc. |
Human anti-opgl neutralizing antibodies as selective opgl pathway inhibitors
|
US7135310B2
(en)
|
2002-04-24 |
2006-11-14 |
The Regents Of The University Of California |
Method to amplify variable sequences without imposing primer sequences
|
PT1506236E
(pt)
|
2002-05-22 |
2013-03-27 |
Esbatech A Novartis Co Llc |
Estruturas de imunoglobulina que demonstram estabilidade aumentada no ambiente intracelular e métodos de identificação das mesmas
|
AU2003239966B9
(en)
|
2002-06-03 |
2010-08-26 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
EP2305710A3
(en)
|
2002-06-03 |
2013-05-29 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
GB0213745D0
(en)
|
2002-06-14 |
2002-07-24 |
Univ Edinburgh |
Enzyme
|
US7425618B2
(en)
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
US7696320B2
(en)
|
2004-08-24 |
2010-04-13 |
Domantis Limited |
Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
|
US20060002935A1
(en)
|
2002-06-28 |
2006-01-05 |
Domantis Limited |
Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor
|
US9028822B2
(en)
|
2002-06-28 |
2015-05-12 |
Domantis Limited |
Antagonists against TNFR1 and methods of use therefor
|
EP1600459A3
(en)
*
|
2002-06-28 |
2005-12-07 |
Domantis Limited |
Ligand
|
WO2004015425A1
(en)
|
2002-08-07 |
2004-02-19 |
Umc Utrecht Holding B.V. |
Modulation of platelet adhesion based on the surface exposed beta-switch loop of platelet glycoprotein ib-alpha
|
US20040067532A1
(en)
|
2002-08-12 |
2004-04-08 |
Genetastix Corporation |
High throughput generation and affinity maturation of humanized antibody
|
PL377091A1
(pl)
|
2002-09-06 |
2006-01-23 |
Amgen, Inc. |
Ludzkie monoklonalne przeciwciało przeciw-IL-1R1, o właściwościach terapeutycznych
|
ATE537186T1
(de)
|
2002-10-07 |
2011-12-15 |
Ludwig Inst For Cancer Res Ltd |
P53-bindendes polypeptid
|
WO2004034988A2
(en)
|
2002-10-16 |
2004-04-29 |
Amgen Inc. |
Human anti-ifn-ϝ neutralizing antibodies as selective ifn-ϝ pathway inhibitors
|
US9701754B1
(en)
|
2002-10-23 |
2017-07-11 |
City Of Hope |
Covalent disulfide-linked diabodies and uses thereof
|
US20060034845A1
(en)
|
2002-11-08 |
2006-02-16 |
Karen Silence |
Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
EP2284192A3
(en)
*
|
2002-11-08 |
2011-07-20 |
Ablynx N.V. |
Camelidae antibodies for sublingual administration
|
AU2003290330A1
(en)
*
|
2002-12-27 |
2004-07-22 |
Domantis Limited |
Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand
|
GB0230203D0
(en)
*
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Fc fusion
|
GB0230201D0
(en)
*
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Retargeting
|
CN100439400C
(zh)
|
2003-01-10 |
2008-12-03 |
埃博灵克斯股份有限公司 |
治疗性多肽,其同源物、其片段及其在调节血小板介导的聚集方面的应用
|
AU2004207741B2
(en)
*
|
2003-01-24 |
2011-02-10 |
Applied Molecular Evolution, Inc |
Human IL-1 beta antagonists
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
WO2004085648A2
(en)
|
2003-03-19 |
2004-10-07 |
Biogen Idec Ma Inc. |
Nogo receptor binding protein
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
US9708410B2
(en)
|
2003-05-30 |
2017-07-18 |
Janssen Biotech, Inc. |
Anti-tissue factor antibodies and compositions
|
EP1498133A1
(en)
|
2003-07-18 |
2005-01-19 |
Aventis Pharma Deutschland GmbH |
Use of a pak inhibitor for the treatment of a joint disease
|
WO2005012531A2
(en)
*
|
2003-08-01 |
2005-02-10 |
Genentech, Inc. |
Antibody cdr polypeptide sequences with restricted diversity
|
US20050106667A1
(en)
|
2003-08-01 |
2005-05-19 |
Genentech, Inc |
Binding polypeptides with restricted diversity sequences
|
US7758859B2
(en)
|
2003-08-01 |
2010-07-20 |
Genentech, Inc. |
Anti-VEGF antibodies
|
EP2325339A3
(en)
*
|
2003-09-09 |
2011-11-02 |
Integrigen, Inc. |
Methods and compositions for generation of germline human antibody genes
|
ES2339710T5
(es)
|
2003-09-23 |
2017-10-05 |
University Of North Carolina At Chapel Hill |
Células que coexpresan vitamina K reductasa y proteína dependiente de vitamina K y uso de las mismas para mejorar la productividad de dicha proteína dependiente de vitamina K
|
PL2189523T3
(pl)
|
2003-10-14 |
2012-05-31 |
Baxalta Inc |
Polipeptyd przekształcający epoksyd witaminy K VKORC1, obiekt działania leczniczego kumaryny i jej pochodnych
|
EP2385069A3
(en)
|
2003-11-12 |
2012-05-30 |
Biogen Idec MA Inc. |
Neonatal Fc rReceptor (FcRn)- binding polypeptide variants, dimeric Fc binding proteins and methods related thereto
|
EP1697750B1
(en)
|
2003-12-01 |
2013-03-20 |
Dako Denmark A/S |
Methods and compositions for immuno-histochemical detection
|
GB0328690D0
(en)
|
2003-12-10 |
2004-01-14 |
Ludwig Inst Cancer Res |
Tumour suppressor protein
|
DK3718564T3
(da)
|
2003-12-23 |
2023-11-06 |
Genentech Inc |
Nye anti-IL-13-antistoffer og anvendelser
|
EP1761561B1
(en)
*
|
2004-01-20 |
2015-08-26 |
KaloBios Pharmaceuticals, Inc. |
Antibody specificity transfer using minimal essential binding determinants
|
GB0406215D0
(en)
|
2004-03-19 |
2004-04-21 |
Procure Therapeutics Ltd |
Prostate stem cell
|
ATE515515T1
(de)
|
2004-03-30 |
2011-07-15 |
Glaxo Group Ltd |
Immunglobuline gegen menschlisches osm
|
US7785903B2
(en)
|
2004-04-09 |
2010-08-31 |
Genentech, Inc. |
Variable domain library and uses
|
CA2562764A1
(en)
|
2004-04-23 |
2005-11-03 |
Richard Kroczek |
Method for the treatment of t cell mediated conditions by depletion of icos-positive cells in vivo
|
EP1750747A1
(en)
|
2004-05-07 |
2007-02-14 |
Astellas US LLC |
Soluble lfa-3 polypeptide for treating viral disorders
|
MXPA06014031A
(es)
|
2004-06-01 |
2007-10-08 |
Domantis Ltd |
Anticuerpos de fusion biespecificos con vida media de serica mejorada.
|
EP1751181B1
(en)
|
2004-06-02 |
2012-08-15 |
AdAlta Pty Ltd |
BINDING MOIETIES BASED ON SHARK IgNAR DOMAINS
|
KR101239542B1
(ko)
|
2004-06-24 |
2013-03-07 |
바이오겐 아이덱 엠에이 인코포레이티드 |
탈수초화를 수반하는 병의 치료
|
TWI307630B
(en)
|
2004-07-01 |
2009-03-21 |
Glaxo Group Ltd |
Immunoglobulins
|
GB0414886D0
(en)
|
2004-07-02 |
2004-08-04 |
Neutec Pharma Plc |
Treatment of bacterial infections
|
NZ552264A
(en)
|
2004-07-20 |
2010-03-26 |
Symphogen As |
A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line
|
NZ552265A
(en)
|
2004-07-20 |
2009-04-30 |
Symphogen As |
Anti-rhesus D recombinant polyclonal antibody and methods of manufacture
|
EP3272770B1
(en)
|
2004-07-22 |
2023-12-20 |
Erasmus University Medical Center Rotterdam |
Method for the production of a vh heavy chain-only antibody in a transgenic mammal and binding polypeptide complex consisting of a dimer of a first chain and a second chain wherein each chain consists of two antigen-specific vh binding domains linked by a dimerisation domain
|
GB0416487D0
(en)
|
2004-07-23 |
2004-08-25 |
Isis Innovation |
Modified virus
|
CA2576193A1
(en)
|
2004-08-03 |
2006-02-16 |
Biogen Idec Ma Inc. |
Taj in neuronal function
|
US7563443B2
(en)
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
ES2881353T3
(es)
*
|
2004-11-16 |
2021-11-29 |
Humanigen Inc |
Intercambio de casetes de la región variable de la inmunoglobulina
|
GB0425739D0
(en)
*
|
2004-11-23 |
2004-12-22 |
Procure Therapeutics Ltd |
Humanised baculovirus 2
|
GB0521621D0
(en)
|
2005-10-24 |
2005-11-30 |
Domantis Ltd |
Tumor necrosis factor receptor 1 antagonists for treating respiratory diseases
|
FR2879605B1
(fr)
|
2004-12-16 |
2008-10-17 |
Centre Nat Rech Scient Cnrse |
Production de formats d'anticorps et applications immunologiques de ces formats
|
EP2298889A1
(en)
|
2004-12-30 |
2011-03-23 |
Agency for Science, Technology and Research |
Chinese hamster apoptosis-related genes
|
WO2006074397A2
(en)
|
2005-01-05 |
2006-07-13 |
Biogen Idec Ma Inc. |
Cripto binding molecules
|
DE602006015281D1
(de)
|
2005-01-14 |
2010-08-19 |
Ablynx Nv |
Verfahren und testvorrichtungen zur unterscheidung verschiedener formen von krankheiten und leiden, die durch thrombocytopenia und/oder durch spontane interaktionen zwischen dem von-willebrand-faktor und plättchen gekennzeichnet sind
|
EP1861711B1
(en)
|
2005-03-11 |
2012-01-11 |
Sanofi |
Use of mgc4504
|
EP1861499A4
(en)
|
2005-03-15 |
2008-09-03 |
Univ North Carolina |
METHODS AND COMPOSITIONS FOR THE PRODUCTION OF ACTIVE PROTEINS DEPENDENT ON VITAMIN K
|
EP1863531A1
(en)
|
2005-03-19 |
2007-12-12 |
Medical Research Council |
Improvements in or relating to treatment and prevention of viral infections
|
JP5238936B2
(ja)
|
2005-03-25 |
2013-07-17 |
ジーアイティーアール,インク. |
Gitr結合分子およびその使用
|
US8084198B2
(en)
|
2005-05-11 |
2011-12-27 |
Sanofi-Aventis |
Use of a GIP promoter polymorphism
|
BR122013001996B1
(pt)
|
2005-05-18 |
2022-02-01 |
Ablynx N.V. |
Nanocorpos melhorados contra fator alfa de necrose tumoral
|
TW200716174A
(en)
|
2005-05-19 |
2007-05-01 |
Centocor Inc |
Anti-MCP-1 antibodies, compositions, methods and uses
|
RU2433139C2
(ru)
|
2005-05-20 |
2011-11-10 |
Аблинкс Н.В. |
Nanobodies tm для лечения заболеваний, опосредованных агрегацией
|
CA2611519A1
(en)
|
2005-06-17 |
2006-12-28 |
Tolerx, Inc. |
Ilt3 binding molecules and uses therefor
|
CN103145840A
(zh)
|
2005-06-30 |
2013-06-12 |
Abbvie公司 |
Il-12/p40结合蛋白
|
EP2238986A3
(en)
|
2005-07-08 |
2010-11-03 |
Biogen Idec MA Inc. |
Sp35 antibodies and uses thereof
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
EP2500359A3
(en)
|
2005-08-19 |
2012-10-17 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
EP1928506A4
(en)
|
2005-08-19 |
2009-10-21 |
Abbott Lab |
IMMUNOGLOBULIN HAVING TWO VARIABLE DOMAINS AND USES THEREOF
|
PL1931710T3
(pl)
|
2005-08-31 |
2017-06-30 |
Merck Sharp & Dohme Corp. |
Przeciwciała anty-il-23 skonstruowane techniką inżynierii genetycznej
|
CA2624562A1
(en)
|
2005-09-30 |
2007-04-12 |
Abbott Gmbh & Co. Kg |
Binding domains of proteins of the repulsive guidance molecule (rgm) protein family and functional fragments thereof, and their use
|
CA2624644C
(en)
|
2005-10-03 |
2014-09-02 |
Smith & Nephew, Inc. |
Locking instrument assembly
|
DE102005048898A1
(de)
|
2005-10-12 |
2007-04-19 |
Sanofi-Aventis Deutschland Gmbh |
EGLN2-Varianten und ihre Verwendung bei der Vorbeugung oder Behandlung thromboembolischer Erkrankungen und koronarer Herzerkrankungen
|
GB0521139D0
(en)
|
2005-10-18 |
2005-11-23 |
Univ Sheffield |
Therapeutic agent
|
US20090155850A1
(en)
*
|
2005-10-28 |
2009-06-18 |
The Florida International University Board Of Trustees |
Horse:Human Chimeric Antibodies
|
NZ568705A
(en)
|
2005-11-04 |
2012-07-27 |
Biogen Idec Inc |
Methods for promoting neurite outgrowth and survival of dopaminergic neurons
|
JP2009514888A
(ja)
|
2005-11-04 |
2009-04-09 |
ジェネンテック・インコーポレーテッド |
眼疾患を処置するための補体経路の阻害剤の使用
|
EP1957531B1
(en)
|
2005-11-07 |
2016-04-13 |
Genentech, Inc. |
Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
|
UA96139C2
(uk)
|
2005-11-08 |
2011-10-10 |
Дженентек, Інк. |
Антитіло до нейропіліну-1 (nrp1)
|
US7820165B2
(en)
|
2005-11-21 |
2010-10-26 |
Merck Serono, S.A. |
Compositions and methods of producing hybrid antigen binding molecules and uses thereof
|
ES2524984T3
(es)
|
2005-11-30 |
2014-12-16 |
Abbvie Inc. |
Anticuerpos anti-globulómero a?, porciones de unión a antígeno de estos, hibridomas correspondientes, ácidos nucleicos, vectores, células huésped, métodos para producir dichos anticuerpos, composiciones que comprenden dichos anticuerpos, usos de dichos anticuerpos, y métodos para usar dichos anticuerpos
|
PT1976877E
(pt)
|
2005-11-30 |
2014-04-29 |
Abbvie Inc |
Anticorpos monoclonais contra proteína beta-amilóide e suas utilizações
|
EP1957536A2
(en)
*
|
2005-12-01 |
2008-08-20 |
Domantis Limited |
Noncompetitive domain antibody formats that bind interleukin 1 receptor type 1
|
JP5312039B2
(ja)
|
2005-12-02 |
2013-10-09 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
脱髄の関与する状態の処置
|
AU2006338198B2
(en)
|
2005-12-02 |
2012-04-26 |
Genentech, Inc. |
Binding polypeptides and uses thereof
|
WO2007064919A2
(en)
*
|
2005-12-02 |
2007-06-07 |
Genentech, Inc. |
Binding polypeptides with restricted diversity sequences
|
EP1954719A2
(en)
|
2005-12-02 |
2008-08-13 |
Genentech Inc. |
Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r
|
DK1981902T3
(en)
|
2006-01-27 |
2015-10-05 |
Biogen Ma Inc |
Nogo Receptor Antagonists
|
US7846439B2
(en)
|
2006-02-01 |
2010-12-07 |
Cephalon Australia Pty Ltd |
Domain antibody construct
|
EP2010677A4
(en)
|
2006-02-24 |
2010-04-14 |
Investigen Inc |
METHODS AND COMPOSITIONS FOR DETECTION OF POLYNUCLEOTIDES
|
US8940871B2
(en)
|
2006-03-20 |
2015-01-27 |
The Regents Of The University Of California |
Engineered anti-prostate stem cell antigen (PSCA) antibodies for cancer targeting
|
EP1999147A1
(en)
*
|
2006-03-27 |
2008-12-10 |
Ablynx N.V. |
Medical delivery device for therapeutic proteins based on single domain antibodies
|
JP2009536527A
(ja)
*
|
2006-05-09 |
2009-10-15 |
ジェネンテック・インコーポレーテッド |
最適化されたスキャフォールドを備えた結合ポリペプチド
|
MX2008015132A
(es)
|
2006-05-30 |
2008-12-10 |
Genentech Inc |
Anticuerpos e inmunoconjugados y sus usos.
|
GB0611116D0
(en)
|
2006-06-06 |
2006-07-19 |
Oxford Genome Sciences Uk Ltd |
Proteins
|
WO2010123874A1
(en)
|
2009-04-20 |
2010-10-28 |
Oxford Biotherapeutics Ltd. |
Antibodies specific to cadherin-17
|
AU2007345745C1
(en)
|
2006-06-19 |
2013-05-23 |
Merck Sharp & Dohme Corp. |
ILT3 binding molecules and uses therefor
|
US8874380B2
(en)
|
2010-12-09 |
2014-10-28 |
Rutgers, The State University Of New Jersey |
Method of overcoming therapeutic limitations of nonuniform distribution of radiopharmaceuticals and chemotherapy drugs
|
BRPI0715115A2
(pt)
*
|
2006-08-03 |
2013-06-04 |
Vaccinex Inc |
anticorpo monoclonal isolado, molÉcula de Ácido nucleico isolada, vetor de expressço, cÉlula hospedeira, mÉtodos para tratar uma doenÇa, e para produzir um anticorpo monoclonal isolado, uso do anticorpo monoclonal isolado, e, composiÇço farmacÊutica
|
WO2008027236A2
(en)
|
2006-08-30 |
2008-03-06 |
Genentech, Inc. |
Multispecific antibodies
|
US20110182904A1
(en)
|
2006-09-05 |
2011-07-28 |
Deborah Zimmerman |
Antibodies to bone morphogenic proteins and receptors therefor and methods for their use
|
TW201522372A
(zh)
|
2006-09-08 |
2015-06-16 |
艾伯維巴哈馬有限公司 |
介白素-13結合蛋白質
|
EP2061906B1
(en)
|
2006-09-12 |
2011-08-31 |
Genentech, Inc. |
Methods and compositions for the diagnosis and treatment of lung cancer using pdgfra, kit or kdr gene as genetic marker
|
JP5417175B2
(ja)
|
2006-10-02 |
2014-02-12 |
メダレックス・リミテッド・ライアビリティ・カンパニー |
Cxcr4に結合するヒト抗体およびその使用
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
GB0620705D0
(en)
|
2006-10-18 |
2006-11-29 |
Opsona Therapeutics |
Compounds for the modulation of toll-like receptor activity and assay methods for the identification of said compounds
|
US8436147B2
(en)
|
2006-10-27 |
2013-05-07 |
Genentech, Inc. |
Antibodies and immunoconjugates and uses therefor
|
EP2102239B1
(en)
|
2006-11-30 |
2012-04-25 |
Research Development Foundation |
Improved immunoglobulin libraries
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
CN103172743B
(zh)
|
2006-12-01 |
2015-04-08 |
梅达雷克斯有限责任公司 |
结合cd22的人抗体及其用途
|
CL2007003622A1
(es)
|
2006-12-13 |
2009-08-07 |
Medarex Inc |
Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales.
|
US20100150950A1
(en)
|
2006-12-14 |
2010-06-17 |
Medarex, Inc. |
Human antibodies that bind cd70 and uses thereof
|
JP5059119B2
(ja)
|
2006-12-14 |
2012-10-24 |
シェーリング コーポレイション |
操作された抗tslp抗体
|
TWI419904B
(zh)
|
2006-12-18 |
2013-12-21 |
Genentech Inc |
拮抗劑抗-notch3抗體及其用於預防及治療notch3相關疾病之用途
|
EP2115004A2
(en)
|
2006-12-19 |
2009-11-11 |
Ablynx N.V. |
Amino acid sequences directed against gpcrs and polypeptides comprising the same for the treatment of gpcr-related diseases and disorders
|
US9512236B2
(en)
|
2006-12-19 |
2016-12-06 |
Ablynx N.V. |
Amino acid sequences directed against GPCRS and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
|
WO2012130874A1
(en)
|
2011-03-28 |
2012-10-04 |
Ablynx Nv |
Bispecific anti-cxcr7 immunoglobulin single variable domains
|
EP2102244A2
(en)
|
2006-12-19 |
2009-09-23 |
Ablynx N.V. |
Amino acid sequences directed against a metalloproteinase from the adam family and polypeptides comprising the same for the treatment of adam-related diseases and disorders
|
US8128926B2
(en)
|
2007-01-09 |
2012-03-06 |
Biogen Idec Ma Inc. |
Sp35 antibodies and uses thereof
|
WO2008086006A2
(en)
|
2007-01-09 |
2008-07-17 |
Biogen Idec Ma Inc. |
Sp35 antibodies and uses thereof
|
BRPI0806605A2
(pt)
|
2007-01-16 |
2011-09-06 |
Abbott Lab |
métodos para tratar psorìase
|
WO2008092041A2
(en)
|
2007-01-24 |
2008-07-31 |
Carnegie Mellon University |
Optical biosensors
|
WO2008103702A2
(en)
|
2007-02-23 |
2008-08-28 |
Investigen, Inc. |
Methods and compositions for rapid light-activated isolation and detection of analytes
|
MX2009009080A
(es)
|
2007-02-23 |
2009-11-02 |
Schering Corp |
Anticuerpos anti-interleucina-23p19 manipulados por ingenieria genetica.
|
MX2009009079A
(es)
|
2007-02-23 |
2009-08-31 |
Schering Corp |
Anticuerpos anti-il-23p19 de ingenieria.
|
EP2447719B1
(en)
|
2007-02-26 |
2016-08-24 |
Oxford BioTherapeutics Ltd |
Proteins
|
WO2008104803A2
(en)
|
2007-02-26 |
2008-09-04 |
Oxford Genome Sciences (Uk) Limited |
Proteins
|
US8895004B2
(en)
|
2007-02-27 |
2014-11-25 |
AbbVie Deutschland GmbH & Co. KG |
Method for the treatment of amyloidoses
|
MX2009009283A
(es)
|
2007-02-28 |
2009-11-18 |
Schering Corp |
Anticuerpos anti-interleuquina -23r de ingenieria.
|
MX2009010492A
(es)
|
2007-03-30 |
2009-10-19 |
Abbott Lab |
Elementos de vector de expresion recombinante (reves) para mejorar la expresion de proteinas recombinantes en celulas huesped.
|
US9969797B2
(en)
*
|
2008-04-23 |
2018-05-15 |
Covalent Bioscience Incorporated |
Immunoglobulins directed to bacterial, viral and endogenous polypeptides
|
US20100143336A1
(en)
|
2007-04-26 |
2010-06-10 |
Opsona Therapeutics Limited |
Toll-like receptor binding epitope and compositions for binding thereto
|
EP2599791A1
(en)
|
2007-04-27 |
2013-06-05 |
Genentech, Inc. |
Potent, stable and non-immunosuppressive anti-CD4 antibodies
|
EP2155789B1
(en)
*
|
2007-05-01 |
2013-07-24 |
Research Development Foundation |
Immunoglobulin fc libraries
|
KR101523788B1
(ko)
|
2007-05-17 |
2015-06-26 |
제넨테크, 인크. |
뉴로필린 단편 및 뉴로필린-항체 복합체의 결정 구조
|
EP1997830A1
(en)
|
2007-06-01 |
2008-12-03 |
AIMM Therapeutics B.V. |
RSV specific binding molecules and means for producing them
|
GB0724331D0
(en)
|
2007-12-13 |
2008-01-23 |
Domantis Ltd |
Compositions for pulmonary delivery
|
SG182170A1
(en)
*
|
2007-06-06 |
2012-07-30 |
Domantis Ltd |
Polypeptides, antibody variable domains and antagonists
|
CA2683791A1
(en)
|
2007-06-06 |
2008-12-11 |
Domantis Limited |
Polypeptides, antibody variable domains & antagonists
|
TWI478939B
(zh)
|
2007-06-15 |
2015-04-01 |
Deutsches Krebsforsch |
使用特定抗-l1抗體治療腫瘤
|
ATE550648T1
(de)
|
2007-06-22 |
2012-04-15 |
Genera Istrazivanja D O O |
Adamts4 als blut-biomarker und therapeutisches ziel bei chronischem nierenversagen
|
CA2691940C
(en)
|
2007-07-03 |
2018-03-06 |
Joost Alexander Kolkman |
Methods for providing improved immunoglobulin sequences
|
AU2008275589B2
(en)
|
2007-07-12 |
2013-11-21 |
Gitr, Inc. |
Combination therapies employing GITR binding molecules
|
EP2023144A1
(en)
|
2007-08-01 |
2009-02-11 |
Sanofi-Aventis |
Novel AS160-like protein, test systems, methods and uses involving it for the identification of diabetes type 2 therapeutics
|
EP2170366B1
(en)
|
2007-08-03 |
2013-11-06 |
Opsona Therapeutics Limited |
Use of tlr-2 antagonists for treatment of reperfusion injury and tissue damage
|
BRPI0815983A2
(pt)
|
2007-08-29 |
2018-05-22 |
Sanofi Aventis |
anticorpos anti-cxcr5 humanizados, derivados dos mesmos e seus usos
|
WO2009032949A2
(en)
|
2007-09-04 |
2009-03-12 |
The Regents Of The University Of California |
High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection
|
US8877688B2
(en)
*
|
2007-09-14 |
2014-11-04 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
EP2193146B1
(en)
|
2007-09-14 |
2016-05-25 |
Adimab, LLC |
Rationally designed, synthetic antibody libraries and uses therefor
|
CN101836117B
(zh)
|
2007-09-18 |
2014-07-23 |
丹麦达科有限公司 |
用于检测生物靶点的快速和灵敏的方法
|
US8629246B2
(en)
|
2007-09-26 |
2014-01-14 |
Ucb Pharma S.A. |
Dual specificity antibody fusions
|
CN101874041B
(zh)
|
2007-09-26 |
2013-06-19 |
中外制药株式会社 |
抗体恒定区修饰体
|
EP2050764A1
(en)
*
|
2007-10-15 |
2009-04-22 |
sanofi-aventis |
Novel polyvalent bispecific antibody format and uses thereof
|
EP2514436B1
(en)
|
2007-11-07 |
2017-12-20 |
Genentech, Inc. |
Il-22 for use in treating microbial disorders
|
AU2008326497B2
(en)
|
2007-11-19 |
2014-02-13 |
Genentech, Inc. |
Compositions and methods for inhibiting tumor progression
|
EP2227556B1
(en)
|
2007-11-19 |
2014-08-27 |
Celera Corporation |
Lung cancer markers and uses thereof
|
AU2008329529B2
(en)
|
2007-11-27 |
2015-02-19 |
The University Of British Columbia |
14-3-3 eta antibodies and uses thereof for the diagnosis and treatment of arthritis
|
AU2008328784B2
(en)
|
2007-11-27 |
2014-03-27 |
Ablynx N.V. |
Immunoglobulin constructs
|
AR069501A1
(es)
|
2007-11-30 |
2010-01-27 |
Genentech Inc |
Anticuerpos anti- vegf (factor de crecimiento endotelial vascular)
|
WO2009079212A2
(en)
|
2007-12-03 |
2009-06-25 |
Carnegie Mellon University |
Linked peptide fluorogenic biosensors
|
BRPI0820875B1
(pt)
|
2007-12-14 |
2021-10-19 |
Bristol-Myers Squibb Company |
Molécula de ligação isolada, anticorpo monoclonal humano, composição, molécula de ácido nucleico, vetor e célula hospedeira
|
US8454960B2
(en)
|
2008-01-03 |
2013-06-04 |
The Scripps Research Institute |
Multispecific antibody targeting and multivalency through modular recognition domains
|
US8574577B2
(en)
|
2008-01-03 |
2013-11-05 |
The Scripps Research Institute |
VEGF antibodies comprising modular recognition domains
|
DK2769991T3
(en)
|
2008-01-03 |
2018-12-10 |
Scripps Research Inst |
ANTIBODY TARGETING WITH A MODULAR RECOGNITION AREA
|
US8557242B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
ERBB2 antibodies comprising modular recognition domains
|
US8557243B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
EFGR antibodies comprising modular recognition domains
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
EP2098536A1
(en)
|
2008-03-05 |
2009-09-09 |
4-Antibody AG |
Isolation and identification of antigen- or ligand-specific binding proteins
|
AU2009221106A1
(en)
|
2008-03-05 |
2009-09-11 |
Ablynx Nv |
Novel antigen binding dimer-complexes, methods of making and uses thereof
|
WO2009114815A1
(en)
*
|
2008-03-13 |
2009-09-17 |
Dyax Corp |
Libraries of genetic packages comprising novel hc cdr3 designs
|
RU2497545C2
(ru)
|
2008-03-18 |
2013-11-10 |
Эбботт Лэборетриз |
Способ лечения псориаза (варианты)
|
EP2105742A1
(en)
|
2008-03-26 |
2009-09-30 |
Sanofi-Aventis |
Use of cathepsin C
|
JP5425180B2
(ja)
|
2008-03-27 |
2014-02-26 |
ザイモジェネティクス, インコーポレイテッド |
PDGFRβおよびVEGF−Aを阻害するための組成物および方法
|
NZ588853A
(en)
*
|
2008-03-31 |
2013-07-26 |
Genentech Inc |
Compositions and methods for treating and diagnosing asthma
|
EP2947097A1
(en)
|
2008-04-07 |
2015-11-25 |
Ablynx N.V. |
Amino acid sequences directed against the Notch pathways and uses thereof
|
AU2008201871A1
(en)
*
|
2008-04-16 |
2009-11-26 |
Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts |
Inhibition of angiogenesis and tumor metastasis
|
CA2722409C
(en)
|
2008-04-24 |
2017-12-12 |
Dyax Corp. |
Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs
|
BRPI0910482A2
(pt)
|
2008-04-29 |
2019-09-24 |
Abbott Lab |
imunoglobinas de domínio variável duplo e usos das mesmas
|
JP2010043063A
(ja)
|
2008-05-09 |
2010-02-25 |
Agency For Science Technology & Research |
川崎病の診断及び治療
|
EP3059248A1
(en)
|
2008-05-09 |
2016-08-24 |
Abbvie Deutschland GmbH & Co. KG |
Antibodies to receptor of advanced glycation end products (rage) and uses thereof
|
NZ589036A
(en)
|
2008-05-16 |
2012-07-27 |
Ablynx Nv |
AMINO ACID SEQUENCES DIRECTED AGAINST CXCR4 AND OTHER GPCRs AND COMPOUNDS COMPRISING THE SAME
|
WO2009149185A2
(en)
|
2008-06-03 |
2009-12-10 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
EP2297209A4
(en)
|
2008-06-03 |
2012-08-01 |
Abbott Lab |
IMMUNOGLOBULINS WITH TWO VARIABLE DOMAINS AND USES THEREOF
|
US9193780B2
(en)
|
2008-06-05 |
2015-11-24 |
Ablynx N.V. |
Amino acid sequences directed against envelope proteins of a virus and polypeptides comprising the same for the treatment of viral diseases
|
CN102316894A
(zh)
|
2008-06-20 |
2012-01-11 |
惠氏有限责任公司 |
来自β-溶血性链球菌菌株的ORF1358的组合物和使用方法
|
SG192496A1
(en)
|
2008-07-08 |
2013-08-30 |
Abbott Lab |
Prostaglandin e2 binding proteins and uses thereof
|
US8822645B2
(en)
|
2008-07-08 |
2014-09-02 |
Abbvie Inc. |
Prostaglandin E2 dual variable domain immunoglobulins and uses thereof
|
US8058406B2
(en)
|
2008-07-09 |
2011-11-15 |
Biogen Idec Ma Inc. |
Composition comprising antibodies to LINGO or fragments thereof
|
WO2010011944A2
(en)
|
2008-07-25 |
2010-01-28 |
Wagner Richard W |
Protein screeing methods
|
US8795981B2
(en)
|
2008-08-08 |
2014-08-05 |
Molecular Devices, Llc |
Cell detection
|
WO2010016806A1
(en)
|
2008-08-08 |
2010-02-11 |
Agency For Science, Technology And Research (A*Star) |
Vhz for diagnosis and treatment of cancers
|
CA2733642A1
(en)
|
2008-08-14 |
2010-02-18 |
Cephalon Australia Pty Ltd |
Anti-il-12/il-23 antibodies
|
JP5796831B2
(ja)
|
2008-09-03 |
2015-10-21 |
ジェネンテック, インコーポレイテッド |
多重特異性抗体
|
US8163497B2
(en)
|
2008-09-07 |
2012-04-24 |
Glyconex Inc. |
Anti-extended type I glycosphingolipid antibody, derivatives thereof and use
|
JP5616892B2
(ja)
|
2008-09-12 |
2014-10-29 |
ダコ・デンマーク・エー/エス |
前立腺癌バイオマーカー
|
US8417011B2
(en)
|
2008-09-18 |
2013-04-09 |
Molecular Devices (New Milton) Ltd. |
Colony detection
|
US20100081575A1
(en)
*
|
2008-09-22 |
2010-04-01 |
Robert Anthony Williamson |
Methods for creating diversity in libraries and libraries, display vectors and methods, and displayed molecules
|
US20100093563A1
(en)
*
|
2008-09-22 |
2010-04-15 |
Robert Anthony Williamson |
Methods and vectors for display of molecules and displayed molecules and collections
|
EP2334300B1
(en)
|
2008-09-24 |
2016-02-17 |
The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin |
Composition and method for treatment of preterm labor
|
EP2334705B1
(en)
|
2008-09-26 |
2016-12-14 |
UCB Biopharma SPRL |
Biological products
|
WO2010043650A2
(en)
|
2008-10-14 |
2010-04-22 |
Ablynx Nv |
Amino acid sequences directed against cellular receptors for viruses and bacteria
|
US9393304B2
(en)
|
2008-10-29 |
2016-07-19 |
Ablynx N.V. |
Formulations of single domain antigen binding molecules
|
JP6113404B2
(ja)
|
2008-10-29 |
2017-04-12 |
アブリンクス エン.ヴェー. |
単一ドメイン抗原結合分子の精製方法
|
JP2012508017A
(ja)
|
2008-11-07 |
2012-04-05 |
ファブラス エルエルシー |
抗dll4抗体及びその使用
|
EP2364328A2
(en)
|
2008-12-10 |
2011-09-14 |
Ablynx NV |
Amino acid sequences directed against the angiopoietin/tie system and polypeptides comprising the same for the treatment of diseases and disorders related to angiogenesis
|
EP2373689A1
(en)
|
2008-12-12 |
2011-10-12 |
MedImmune, LLC |
Crystals and structure of a human igg fc variant with enhanced fcrn binding
|
CN107011434B
(zh)
|
2008-12-19 |
2021-02-19 |
埃博灵克斯股份有限公司 |
用于产生针对细胞相关抗原如p2x7、cxcr7或cxcr4的免疫球蛋白的基因免疫
|
AR074777A1
(es)
|
2008-12-19 |
2011-02-09 |
Glaxo Group Ltd |
Proteinas de union a antigeno
|
AU2009334498A1
(en)
|
2008-12-31 |
2011-07-21 |
Biogen Idec Ma Inc. |
Anti-lymphotoxin antibodies
|
WO2010084408A2
(en)
|
2009-01-21 |
2010-07-29 |
Oxford Biotherapeutics Ltd. |
Pta089 protein
|
WO2010085590A1
(en)
|
2009-01-23 |
2010-07-29 |
Biosynexus Incorporated |
Opsonic and protective antibodies specific for lipoteichoic acid gram positive bacteria
|
CA2749966A1
(en)
|
2009-01-29 |
2010-08-05 |
Abbott Laboratories |
Il-1 binding proteins
|
EP2219029A1
(en)
|
2009-01-30 |
2010-08-18 |
Sanofi-Aventis |
Test systems, methods and uses involving AS160 protein
|
ES2712732T3
(es)
|
2009-02-17 |
2019-05-14 |
Cornell Res Foundation Inc |
Métodos y kits para el diagnóstico de cáncer y la predicción de valor terapéutico
|
CA2752385A1
(en)
|
2009-02-19 |
2010-08-26 |
Dako Denmark A/S |
Water soluble conjugate molecules comprising peroxidase substrate moieties
|
US8030026B2
(en)
|
2009-02-24 |
2011-10-04 |
Abbott Laboratories |
Antibodies to troponin I and methods of use thereof
|
EA028336B1
(ru)
|
2009-03-05 |
2017-11-30 |
МЕДАРЕКС Л.Л.Си. |
Полностью человеческие антитела, специфические в отношении cadm1
|
EP2403873A1
(en)
|
2009-03-05 |
2012-01-11 |
Ablynx N.V. |
Novel antigen binding dimer-complexes, methods of making/avoiding and uses thereof
|
WO2010100437A2
(en)
|
2009-03-05 |
2010-09-10 |
University Of Sheffield |
Production of protein
|
SG173705A1
(en)
|
2009-03-05 |
2011-09-29 |
Abbott Lab |
Il-17 binding proteins
|
US8283162B2
(en)
|
2009-03-10 |
2012-10-09 |
Abbott Laboratories |
Antibodies relating to PIVKAII and uses thereof
|
SI3260136T1
(sl)
|
2009-03-17 |
2021-05-31 |
Theraclone Sciences, Inc. |
Humani imunodeficientni virus (HIV)-nevtralizirajoča protitelesa
|
GB0905023D0
(en)
|
2009-03-24 |
2009-05-06 |
Univ Erasmus Medical Ct |
Binding molecules
|
JP5616428B2
(ja)
|
2009-04-07 |
2014-10-29 |
ロシュ グリクアート アクチェンゲゼルシャフト |
三価の二重特異性抗体
|
AU2010233658B2
(en)
|
2009-04-10 |
2013-11-28 |
Ablynx Nv |
Improved amino acid sequences directed against IL-6R and polypeptides comprising the same for the treatment of IL-6R related diseases and disorders
|
US8609101B2
(en)
*
|
2009-04-23 |
2013-12-17 |
Theraclone Sciences, Inc. |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) neutralizing antibodies
|
AU2010243551B2
(en)
|
2009-04-30 |
2015-03-26 |
Ablynx Nv |
Method for the production of domain antibodies
|
BRPI1011195B1
(pt)
*
|
2009-05-20 |
2020-10-13 |
Novimmune S.A |
métodos para produzir uma coleção de ácidos nucleicos
|
EP2435568B1
(en)
|
2009-05-29 |
2014-07-02 |
MorphoSys AG |
Collection of synthetic antibodies for treating disease
|
ES2643034T3
(es)
|
2009-06-05 |
2017-11-21 |
Ablynx N.V. |
Construcciones de Nanobody contra el virus respiratorio sincicial humano (VRSH) trivalentes para la prevención y/o el tratamiento de infecciones de las vías respiratorias
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
WO2011008517A2
(en)
*
|
2009-06-30 |
2011-01-20 |
Research Development Foundation |
Immunoglobulin fc polypeptides
|
CA2766409C
(en)
|
2009-07-03 |
2023-04-25 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them
|
IE20090514A1
(en)
|
2009-07-06 |
2011-02-16 |
Opsona Therapeutics Ltd |
Humanised antibodies and uses therof
|
ES2804450T3
(es)
|
2009-07-10 |
2021-02-08 |
Ablynx Nv |
Método para la producción de dominios variables
|
WO2011014457A1
(en)
|
2009-07-27 |
2011-02-03 |
Genentech, Inc. |
Combination treatments
|
CA2771575A1
(en)
|
2009-08-29 |
2011-03-03 |
Abbott Laboratories |
Therapeutic dll4 binding proteins
|
EP2293072A1
(en)
|
2009-08-31 |
2011-03-09 |
Sanofi-Aventis |
Use of cathepsin H
|
JP5715137B2
(ja)
|
2009-08-31 |
2015-05-07 |
アボット・ラボラトリーズAbbott Laboratories |
主要有害心イベントの予測のためのバイオマーカーおよびその使用
|
UY32870A
(es)
|
2009-09-01 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
EP2473522B1
(en)
|
2009-09-02 |
2016-08-17 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
EP3023438B1
(en)
|
2009-09-03 |
2020-03-11 |
Merck Sharp & Dohme Corp. |
Anti-gitr antibodies
|
EP3725330A1
(en)
|
2009-09-03 |
2020-10-21 |
Ablynx N.V. |
Stable formulations of polypeptides and uses thereof
|
IN2012DN01965A
(es)
|
2009-09-14 |
2015-08-21 |
Abbvie Deutschland |
|
WO2011032181A2
(en)
*
|
2009-09-14 |
2011-03-17 |
Dyax Corp. |
Libraries of genetic packages comprising novel hc cdr3 designs
|
WO2011034605A2
(en)
|
2009-09-16 |
2011-03-24 |
Genentech, Inc. |
Coiled coil and/or tether containing protein complexes and uses thereof
|
WO2011035205A2
(en)
|
2009-09-18 |
2011-03-24 |
Calmune Corporation |
Antibodies against candida, collections thereof and methods of use
|
GB201005063D0
(en)
|
2010-03-25 |
2010-05-12 |
Ucb Pharma Sa |
Biological products
|
US8568726B2
(en)
|
2009-10-06 |
2013-10-29 |
Medimmune Limited |
RSV specific binding molecule
|
US8518405B2
(en)
|
2009-10-08 |
2013-08-27 |
The University Of North Carolina At Charlotte |
Tumor specific antibodies and uses therefor
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
WO2011047083A1
(en)
|
2009-10-13 |
2011-04-21 |
Oxford Biotherapeutics Ltd. |
Antibodies against epha10
|
RU2012119756A
(ru)
|
2009-10-15 |
2013-11-20 |
Эбботт Лэборетриз |
Иммуноглобулины с двумя вариабельными доменами и их применение
|
EP2488186B1
(en)
|
2009-10-16 |
2017-05-24 |
National University of Singapore |
Anti-neoplastic uses of artemin antagonists
|
CN102713626B
(zh)
|
2009-10-20 |
2015-03-04 |
丹麦达科有限公司 |
单个靶实体的免疫化学检测
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
JO3437B1
(ar)
|
2009-10-30 |
2019-10-20 |
Esai R & D Man Co Ltd |
أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها
|
US8420083B2
(en)
|
2009-10-31 |
2013-04-16 |
Abbvie Inc. |
Antibodies to receptor for advanced glycation end products (RAGE) and uses thereof
|
EP2496605A1
(en)
|
2009-11-02 |
2012-09-12 |
Oxford Biotherapeutics Ltd. |
Ror1 as therapeutic and diagnostic target
|
US20110165648A1
(en)
|
2009-11-04 |
2011-07-07 |
Menno Van Lookeren Campagne |
Co-crystal structure of factor D and anti-factor D antibody
|
EP2496600A1
(en)
|
2009-11-04 |
2012-09-12 |
Fabrus LLC |
Methods for affinity maturation-based antibody optimization
|
MX2012005180A
(es)
|
2009-11-04 |
2012-06-08 |
Merck Sharp & Dohme |
Anticuerpo anti-linfopoyetina estromal timica (anti-tslp) modificado por tecnicas de ingenieria genetica.
|
JP2013509869A
(ja)
|
2009-11-05 |
2013-03-21 |
ノバルティス アーゲー |
線維症の進行の予測用バイオマーカー
|
EP2499491B1
(en)
|
2009-11-11 |
2015-04-01 |
Gentian AS |
Immunoassay for assessing related analytes of different origin
|
US9644022B2
(en)
|
2009-11-30 |
2017-05-09 |
Ablynx N.V. |
Amino acid sequences directed against human respiratory syncytial virus (HRSV) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
|
EP3135302A1
(en)
|
2009-12-02 |
2017-03-01 |
Imaginab, Inc. |
J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use
|
JP5951498B2
(ja)
|
2009-12-08 |
2016-07-13 |
アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー |
網膜神経線維層変性の治療に使用するためのrgmaタンパク質に対するモノクローナル抗体
|
WO2011071577A1
(en)
|
2009-12-11 |
2011-06-16 |
Genentech, Inc. |
Anti-vegf-c antibodies and methods using same
|
EP2513145B1
(en)
|
2009-12-14 |
2018-01-24 |
Ablynx N.V. |
Single variable domain antibodies against ox40l, constructs and therapeutic use
|
SG2014011340A
(en)
|
2009-12-21 |
2014-07-30 |
Genentech Inc |
Antibody formulation
|
CA2784610C
(en)
|
2009-12-23 |
2020-07-14 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them
|
MX2012007379A
(es)
|
2009-12-23 |
2012-08-31 |
Genentech Inc |
Anticuerpos anti-bv8 y usos de los mismos.
|
WO2011083140A1
(en)
|
2010-01-08 |
2011-07-14 |
Ablynx Nv |
Immunoglobulin single variable domain directed against human cxcr4
|
TWI513466B
(zh)
|
2010-01-20 |
2015-12-21 |
Boehringer Ingelheim Int |
抗凝血劑解毒劑
|
EA023700B1
(ru)
|
2010-01-28 |
2016-07-29 |
Глаксо Груп Лимитед |
Cd127-связывающие белки
|
EP2354159A1
(en)
|
2010-02-05 |
2011-08-10 |
RWTH Aachen |
CCL17 inhibitors for use in T helper cell-driven diseases
|
WO2011098449A1
(en)
|
2010-02-10 |
2011-08-18 |
Novartis Ag |
Methods and compounds for muscle growth
|
US9120855B2
(en)
|
2010-02-10 |
2015-09-01 |
Novartis Ag |
Biologic compounds directed against death receptor 5
|
AU2011214299B2
(en)
|
2010-02-11 |
2014-07-31 |
Ablynx Nv |
Methods and compositions for the preparation of aerosols
|
RU2587619C2
(ru)
|
2010-02-18 |
2016-06-20 |
Дженентек, Инк. |
Антагонисты неурегулина и применение их в лечении злокачественного новообразования
|
SG183872A1
(en)
|
2010-03-02 |
2012-11-29 |
Abbvie Inc |
Therapeutic dll4 binding proteins
|
UA108227C2
(xx)
|
2010-03-03 |
2015-04-10 |
|
Антигензв'язуючий білок
|
GB201003701D0
(en)
|
2010-03-05 |
2010-04-21 |
Cilian Ag |
System for the expression of a protein
|
SG10201504808XA
(en)
|
2010-03-17 |
2015-07-30 |
Abbott Res Bv |
Anti-Nerve Growth Factor (NGF) Antibody Compositions
|
WO2011119661A1
(en)
|
2010-03-24 |
2011-09-29 |
Genentech, Inc. |
Anti-lrp6 antibodies
|
EP2552962B1
(en)
|
2010-03-26 |
2016-03-23 |
Ablynx N.V. |
Immunoglobulin single variable domains directed against cxcr7
|
AR080793A1
(es)
|
2010-03-26 |
2012-05-09 |
Roche Glycart Ag |
Anticuerpos biespecificos
|
MX336196B
(es)
|
2010-04-15 |
2016-01-11 |
Abbvie Inc |
Proteinas de union a amiloide beta.
|
AU2011249783B9
(en)
|
2010-05-06 |
2014-11-06 |
Novartis Ag |
Compositions and methods of use for therapeutic low density lipoprotein -related protein 6 (LRP6) antibodies
|
BR112012028326A2
(pt)
|
2010-05-06 |
2017-03-21 |
Novartis Ag |
anticorpo multivalente isolado, anticorpos biparatópicos isolados, ácido nucleico, vetor, composição farmacêutica, método de obtenção dos referidos anticorpos, bem como uso do dos mesmos
|
PL2571532T3
(pl)
|
2010-05-14 |
2017-10-31 |
Abbvie Inc |
Białka wiążące IL-1
|
KR20130080790A
(ko)
|
2010-05-20 |
2013-07-15 |
아블린쓰 엔.브이. |
Her3와 관련된 생물학적 물질들
|
EP2577309B1
(en)
|
2010-05-25 |
2016-11-23 |
Carnegie Mellon University |
Targeted probes of cellular physiology
|
WO2011147834A1
(en)
|
2010-05-26 |
2011-12-01 |
Roche Glycart Ag |
Antibodies against cd19 and uses thereof
|
AU2011261362B2
(en)
|
2010-06-03 |
2016-06-09 |
Genentech, Inc. |
Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
|
AR081556A1
(es)
|
2010-06-03 |
2012-10-03 |
Glaxo Group Ltd |
Proteinas de union al antigeno humanizadas
|
WO2011161545A2
(en)
|
2010-06-04 |
2011-12-29 |
The Netherlands Cancer Institute |
Non-hydrolyzable protein conjugates, methods and compositions related thereto
|
WO2011158019A1
(en)
|
2010-06-16 |
2011-12-22 |
Adjuvantix Limited |
Polypeptide vaccine
|
TW201204388A
(en)
|
2010-06-18 |
2012-02-01 |
Genentech Inc |
Anti-Axl antibodies and methods of use
|
WO2011161119A1
(en)
|
2010-06-22 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Antibodies against insulin-like growth factor i receptor and uses thereof
|
WO2011161189A1
(en)
|
2010-06-24 |
2011-12-29 |
F. Hoffmann-La Roche Ag |
Anti-hepsin antibodies and methods of use
|
WO2011161263A1
(en)
|
2010-06-25 |
2011-12-29 |
Ablynx Nv |
Pharmaceutical compositions for cutaneous administration
|
US20120009196A1
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
AU2011274423B2
(en)
|
2010-07-09 |
2016-02-11 |
Bioverativ Therapeutics Inc. |
Chimeric clotting factors
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
JP2013539962A
(ja)
|
2010-07-09 |
2013-10-31 |
ジェネンテック, インコーポレイテッド |
抗ニューロピリン抗体及び使用方法
|
WO2012009705A1
(en)
|
2010-07-15 |
2012-01-19 |
Zyngenia, Inc. |
Ang-2 binding complexes and uses thereof
|
AU2011279073B2
(en)
|
2010-07-16 |
2016-06-09 |
Adimab, Llc |
Antibody libraries
|
WO2012009760A1
(en)
|
2010-07-20 |
2012-01-26 |
Cephalon Australia Pty Ltd |
Anti-il-23 heterodimer specific antibodies
|
WO2012010582A1
(en)
|
2010-07-21 |
2012-01-26 |
Roche Glycart Ag |
Anti-cxcr5 antibodies and methods of use
|
US9120862B2
(en)
|
2010-07-26 |
2015-09-01 |
Abbott Laboratories |
Antibodies relating to PIVKA-II and uses thereof
|
PE20131412A1
(es)
|
2010-08-03 |
2014-01-19 |
Abbvie Inc |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
CA2806855A1
(en)
|
2010-08-03 |
2012-02-09 |
F. Hoffmann - La Roche Ag |
Chronic lymphocytic leukemia (cll) biomarkers
|
CN103209709A
(zh)
|
2010-08-05 |
2013-07-17 |
弗·哈夫曼-拉罗切有限公司 |
抗mhc抗体抗病毒性细胞因子融合蛋白
|
JP2013537416A
(ja)
|
2010-08-13 |
2013-10-03 |
メディミューン リミテッド |
変異型Fc領域を含むモノマーポリペプチド及び使用方法
|
BR112013002444A2
(pt)
|
2010-08-13 |
2016-05-24 |
Roche Glycart Ag |
anticorpo, polinucleotídeo e polipeotídeo isolados, composição, vetor, cécula hospedeira, conjulgado de anticorpo, formulação farmacêutica, uso do anticorpo, métodos para produzir um anticorpo, tratar um indivíduo, induzir a lise celular de uma célula tumorosa e diagnosticar uma doença em um indivíduo
|
KR101673653B1
(ko)
|
2010-08-13 |
2016-11-08 |
로슈 글리카트 아게 |
항-fap 항체 및 이의 사용 방법
|
EP3533803B1
(en)
|
2010-08-14 |
2021-10-27 |
AbbVie Inc. |
Anti-amyloid-beta antibodies
|
WO2012022734A2
(en)
|
2010-08-16 |
2012-02-23 |
Medimmune Limited |
Anti-icam-1 antibodies and methods of use
|
HUE058226T2
(hu)
|
2010-08-19 |
2022-07-28 |
Zoetis Belgium S A |
NGF elleni antitestek és alkalmazásuk
|
ES2620255T3
(es)
|
2010-08-20 |
2017-06-28 |
Novartis Ag |
Anticuerpos para el receptor del factor de crecimiento epidérmico 3 (HER3)
|
JP5758004B2
(ja)
|
2010-08-24 |
2015-08-05 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
ジスルフィドによって安定化されたFv断片を含む二重特異性抗体
|
KR101603001B1
(ko)
|
2010-08-25 |
2016-03-11 |
에프. 호프만-라 로슈 아게 |
Il-18r1에 대한 항체 및 그의 용도
|
PE20140229A1
(es)
|
2010-08-26 |
2014-03-27 |
Abbvie Inc |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
CA2808236A1
(en)
|
2010-08-31 |
2012-03-08 |
Genentech, Inc. |
Biomarkers and methods of treatment
|
EP4226935A3
(en)
|
2010-08-31 |
2023-09-06 |
Theraclone Sciences, Inc. |
Human immunodeficiency virus (hiv)-neutralizing antibodies
|
CN103201293B
(zh)
|
2010-09-08 |
2016-04-27 |
哈洛齐梅公司 |
评估和鉴定或发展条件活性治疗蛋白的方法
|
HUE041958T2
(hu)
|
2010-09-09 |
2019-06-28 |
Pfizer |
4-IBB-t kötõ molekulák
|
WO2012038744A2
(en)
|
2010-09-22 |
2012-03-29 |
Genome Research Limited |
Detecting mutations
|
US8497138B2
(en)
|
2010-09-30 |
2013-07-30 |
Genetix Limited |
Method for cell selection
|
GB201016494D0
(en)
|
2010-09-30 |
2010-11-17 |
Queen Mary Innovation Ltd |
Polypeptide
|
US8481680B2
(en)
|
2010-10-05 |
2013-07-09 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
US20130261288A1
(en)
|
2010-10-29 |
2013-10-03 |
Ablynx N.V. |
Method for the production of immunoglobulin single variable domains
|
CA2815266C
(en)
|
2010-11-05 |
2023-09-05 |
Zymeworks Inc. |
Stable heterodimeric antibody design with mutations in the fc domain
|
EP3575321B1
(en)
|
2010-11-08 |
2023-07-26 |
Ablynx N.V. |
Cxcr2 binding polypeptides
|
CA2816472A1
(en)
|
2010-11-08 |
2012-05-18 |
Dako Denmark A/S |
Quantification of single target molecules in histological samples
|
AR083819A1
(es)
|
2010-11-10 |
2013-03-27 |
Genentech Inc |
UN ANTICUERPO QUE SE UNE A BACE1 (ENZIMA 1 DE DISOCIACION DE PROTEINA PRECURSORA DEL AMILOIDE DE SITIO b), METODOS Y COMPOSICIONES PARA INMUNOTERAPIA PARA ENFERMEDAD NEURAL
|
CA2816558C
(en)
|
2010-11-19 |
2020-12-29 |
Morphosys Ag |
A collection and methods for its use
|
WO2012076010A1
(en)
|
2010-12-06 |
2012-06-14 |
Dako Denmark A/S |
Combined histological stain
|
TWI666447B
(zh)
|
2010-12-16 |
2019-07-21 |
建南德克公司 |
關於th2抑制作用之診斷及治療
|
TW201238974A
(en)
|
2010-12-17 |
2012-10-01 |
Sanofi Sa |
MiRNAs in joint disease
|
TW201241179A
(en)
|
2010-12-17 |
2012-10-16 |
Sanofi Sa |
MiRNAs in joint disease
|
TW201238973A
(en)
|
2010-12-17 |
2012-10-01 |
Sanofi Sa |
MiRNAs in joint disease
|
TW201239097A
(en)
|
2010-12-17 |
2012-10-01 |
Sanofi Sa |
MiRNAs in joint disease
|
KR20140014116A
(ko)
|
2010-12-20 |
2014-02-05 |
제넨테크, 인크. |
항-메소텔린 항체 및 면역접합체
|
WO2012088222A2
(en)
|
2010-12-21 |
2012-06-28 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for producing active vitamin k-dependent proteins
|
EP2655417A2
(en)
|
2010-12-21 |
2013-10-30 |
AbbVie Inc. |
Il-1 -alpha and -beta bispecific dual variable domain immunoglobulins and their use
|
US20120275996A1
(en)
|
2010-12-21 |
2012-11-01 |
Abbott Laboratories |
IL-1 Binding Proteins
|
BR112013015687A2
(pt)
|
2010-12-22 |
2016-10-11 |
Genentech Inc |
anticorpo anti-pcsk9 ou um fragmento de anticorpo que se liga a pcsk9, ácido nucleico isolado, vetor, célula hospedeira, método para fabricar um anticorpo anti-pcsk9, composição farmacêutica, método de redução do nível de colesterol ldl em um sujeito e método de tratamento de hipercolesterolemia em um sujeito
|
WO2012085113A1
(en)
|
2010-12-23 |
2012-06-28 |
Roche Diagnostics Gmbh |
Binding agent
|
CA2817928C
(en)
|
2010-12-23 |
2019-10-01 |
Michael Gerg |
Detection of a posttranslationally modified polypeptide by a bi-valent binding agent
|
CN103384831B
(zh)
|
2010-12-23 |
2016-02-10 |
霍夫曼-拉罗奇有限公司 |
通过二价结合剂来检测多肽二聚体
|
WO2012085111A1
(en)
|
2010-12-23 |
2012-06-28 |
F. Hoffmann-La Roche Ag |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
WO2012092323A1
(en)
|
2010-12-28 |
2012-07-05 |
Xoma Technology Ltd. |
Cell surface display using pdz domains
|
EP2471554A1
(en)
|
2010-12-28 |
2012-07-04 |
Hexal AG |
Pharmaceutical formulation comprising a biopharmaceutical drug
|
AU2012214643B2
(en)
|
2011-02-07 |
2016-12-15 |
Research Development Foundation |
Engineered immunoglobulin Fc polypeptides
|
CA2824252A1
(en)
|
2011-02-10 |
2012-08-16 |
Roche Glycart Ag |
Improved immunotherapy
|
EP2673297A2
(en)
|
2011-02-11 |
2013-12-18 |
Zyngenia, Inc. |
Monovalent and multivalent multispecific complexes and uses thereof
|
CA2825081A1
(en)
|
2011-02-28 |
2012-09-07 |
Birgit Bossenmaier |
Antigen binding proteins
|
EP2681240B1
(en)
|
2011-02-28 |
2017-08-16 |
F. Hoffmann-La Roche AG |
Monovalent antigen binding proteins
|
EP2686016B1
(en)
|
2011-03-14 |
2019-05-01 |
Cellmid Limited |
Antibody recognizing n-domain of midkine
|
AR085911A1
(es)
|
2011-03-16 |
2013-11-06 |
Sanofi Sa |
Dosis terapeutica segura de una proteina similar a un anticuerpo con region v dual
|
WO2012130872A1
(en)
|
2011-03-28 |
2012-10-04 |
Ablynx Nv |
Method for producing solid formulations comprising immunoglobulin single variable domains
|
CN103476795B
(zh)
|
2011-03-29 |
2016-07-06 |
罗切格利卡特公司 |
抗体Fc变体
|
WO2012130834A1
(en)
|
2011-03-30 |
2012-10-04 |
Boehringer Ingelheim International Gmbh |
Anticoagulant antidotes
|
KR20140021589A
(ko)
|
2011-04-07 |
2014-02-20 |
제넨테크, 인크. |
항-fgfr4 항체 및 사용 방법
|
EP2511293A1
(en)
|
2011-04-13 |
2012-10-17 |
LEK Pharmaceuticals d.d. |
A method for controlling the main complex N-glycan structures and the acidic variants and variability in bioprocesses producing recombinant proteins
|
CN103597089B
(zh)
|
2011-04-19 |
2017-04-12 |
丹麦达科有限公司 |
用于酶介导的信号放大的方法
|
RU2013150331A
(ru)
|
2011-04-20 |
2015-05-27 |
Рош Гликарт Аг |
СПОСОБ И УСТРОЙСТВА ДЛЯ рН-ЗАВИСИМОГО ПРОХОЖДЕНИЯ ГЕМАТОЭНЦЕФАЛИЧЕСКОГО БАРЬЕРА
|
CA2833404A1
(en)
|
2011-04-21 |
2012-10-26 |
Garvan Institute Of Medical Research |
Modified variable domain molecules and methods for producing and using them b
|
EP2518157A1
(en)
|
2011-04-26 |
2012-10-31 |
Sanofi |
Test Systems and methods for identifying a compound altering cellular DDR activity
|
US9062106B2
(en)
|
2011-04-27 |
2015-06-23 |
Abbvie Inc. |
Methods for controlling the galactosylation profile of recombinantly-expressed proteins
|
EA201892619A1
(ru)
|
2011-04-29 |
2019-04-30 |
Роше Гликарт Аг |
Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
|
UA117218C2
(uk)
|
2011-05-05 |
2018-07-10 |
Мерк Патент Гмбх |
Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
|
GB201114858D0
(en)
|
2011-08-29 |
2011-10-12 |
Nvip Pty Ltd |
Anti-nerve growth factor antibodies and methods of using the same
|
ES2905682T3
(es)
|
2011-05-06 |
2022-04-11 |
Zoetis Services Llc |
Anticuerpos anti-factor de crecimiento nervioso y métodos de preparación y uso de los mismos
|
CA2835094C
(en)
|
2011-05-06 |
2020-12-22 |
David Gearing |
Anti-nerve growth factor antibodies and methods of preparing and using the same
|
MY160884A
(en)
|
2011-05-06 |
2017-03-31 |
Nexvet Australia Pty Ltd |
Anti-nerve growth factor antibodies and methods of preparing and using the same
|
KR101783929B1
(ko)
|
2011-05-06 |
2017-10-11 |
넥스베트 오스트레일리아 피티와이 리미티드 |
항신경성 성장 인자 항체 및 그의 제조방법과 이용방법
|
US9534039B2
(en)
|
2011-05-09 |
2017-01-03 |
Ablynx N.V. |
Method for the production of immunoglobulin single variable domains
|
WO2012155019A1
(en)
|
2011-05-12 |
2012-11-15 |
Genentech, Inc. |
Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature pepides
|
EP2710035B1
(en)
|
2011-05-16 |
2017-04-12 |
F. Hoffmann-La Roche AG |
Fgfr1 agonists and methods of use
|
CA2836468C
(en)
|
2011-05-17 |
2021-05-04 |
The Rockefeller University |
Human immunodeficiency virus neutralizing antibodies and methods of use thereof
|
AU2012258637B2
(en)
|
2011-05-24 |
2017-07-20 |
Zyngenia, Inc. |
Multivalent and monovalent multispecific complexes and their uses
|
CN108329391A
(zh)
|
2011-05-27 |
2018-07-27 |
埃博灵克斯股份有限公司 |
使用rankl结合肽抑制骨质吸收
|
WO2012166906A1
(en)
|
2011-05-31 |
2012-12-06 |
Massachusetts Institute Of Technology |
Cell-directed synthesis of multifunctional nanopatterns and nanomaterials
|
KR102111171B1
(ko)
|
2011-06-10 |
2020-05-14 |
메디뮨 엘엘씨 |
항슈도모나스 psl 결합 분자 및 그의 용도
|
WO2012171057A1
(en)
|
2011-06-13 |
2012-12-20 |
Csl Limited |
Antibodies against g-csfr and uses thereof
|
JP5984919B2
(ja)
|
2011-06-15 |
2016-09-06 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
抗ヒトepo受容体抗体及び使用方法
|
EP2537532A1
(en)
|
2011-06-22 |
2012-12-26 |
J. Stefan Institute |
Cathepsin-binding compounds bound to a nanodevice and their diagnostic and therapeutic use
|
JP2014525736A
(ja)
|
2011-06-23 |
2014-10-02 |
アブリンクス エン.ヴェー. |
IgEに対する免疫グロブリン単一可変ドメイン
|
EP3363813A1
(en)
|
2011-06-23 |
2018-08-22 |
Ablynx NV |
Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobin single variable domains
|
EP4350345A3
(en)
|
2011-06-23 |
2024-07-24 |
Ablynx N.V. |
Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobin single variable domains
|
CN108659120A
(zh)
|
2011-06-23 |
2018-10-16 |
埃博灵克斯股份有限公司 |
用于预测、检测和减少涉及免疫球蛋白单可变结构域的测定法中的非特异性蛋白干扰的技术
|
JP6247209B2
(ja)
|
2011-06-28 |
2017-12-13 |
オックスフォード ビオトヘラペウトイクス エルティーディー. |
Adpリボシルシクラーゼ2に対する抗体
|
JP6113721B2
(ja)
|
2011-06-28 |
2017-04-12 |
オックスフォード ビオトヘラペウトイクス エルティーディー. |
治療標的及び診断標的
|
SG194932A1
(en)
|
2011-06-30 |
2013-12-30 |
Genentech Inc |
Anti-c-met antibody formulations
|
JP2014520847A
(ja)
|
2011-07-13 |
2014-08-25 |
アッヴィ・インコーポレイテッド |
抗il−13抗体を使用して喘息を治療するための方法および組成物
|
WO2013012733A1
(en)
|
2011-07-15 |
2013-01-24 |
Biogen Idec Ma Inc. |
Heterodimeric fc regions, binding molecules comprising same, and methods relating thereto
|
WO2013016220A1
(en)
|
2011-07-22 |
2013-01-31 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
BR112014003431A2
(pt)
|
2011-08-17 |
2017-06-13 |
Genentech Inc |
anticorpo, ácido nucleico, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, agente farmacêutico, uso do anticorpo, método de tratamento de um indivíduo que tem câncer e método de aumento de tempo para recorrência de tumor
|
US20130058936A1
(en)
|
2011-08-23 |
2013-03-07 |
Peter Bruenker |
Bispecific antibodies specific for t-cell activating antigens and a tumor antigen and methods of use
|
CA2844538C
(en)
|
2011-08-23 |
2020-09-22 |
Roche Glycart Ag |
Bispecific antigen binding molecules
|
US20130078250A1
(en)
|
2011-08-23 |
2013-03-28 |
Oliver Ast |
Bispecific t cell activating antigen binding molecules
|
CA2837975C
(en)
|
2011-08-23 |
2022-04-05 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
BR112014003999A2
(pt)
|
2011-08-23 |
2017-06-13 |
Roche Glycart Ag |
anticorpo isolado que se liga a um epítopo próximo da membrana de mcsp humano, ácido nucleico isolado, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, uso do anticorpo, método de tratamento de indivíduos portadores de câncer, método de undução da lise celular em indivíduos e teste imuno-histoquímico de mcsp
|
AU2012300632A1
(en)
|
2011-08-30 |
2014-03-13 |
Nvip Pty Ltd |
Caninised tumour necrosis factor antibodies and methods of using the same
|
US8822651B2
(en)
|
2011-08-30 |
2014-09-02 |
Theraclone Sciences, Inc. |
Human rhinovirus (HRV) antibodies
|
WO2013034660A1
(en)
|
2011-09-09 |
2013-03-14 |
Medimmune Limited |
Anti-siglec-15 antibodies and uses thereof
|
JP2014527180A
(ja)
|
2011-09-14 |
2014-10-09 |
アベテルノ リミテッド |
細胞内細胞選別
|
JP2014533927A
(ja)
|
2011-09-15 |
2014-12-18 |
ジェネンテック, インコーポレイテッド |
分化を促進する方法
|
EP2758055A1
(en)
|
2011-09-19 |
2014-07-30 |
F.Hoffmann-La Roche Ag |
Combination treatments comprising c-met antagonists and b-raf antagonists
|
SG10201703771WA
(en)
|
2011-09-19 |
2017-06-29 |
Axon Neuroscience Se |
Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease
|
GB201116116D0
(en)
|
2011-09-19 |
2011-11-02 |
Univ York |
Cell differentiation
|
EP2758437B1
(en)
|
2011-09-22 |
2020-06-03 |
Amgen Inc. |
Cd27l antigen binding proteins
|
US10138302B2
(en)
|
2011-09-23 |
2018-11-27 |
Ablynx N.V. |
Methods for treating rheumatoid arthritis by administering interleukin-6 receptor antibodies
|
GB201116702D0
(en)
|
2011-09-28 |
2011-11-09 |
Procure Therapeutics Ltd |
Cell surface markers
|
CA2850549C
(en)
|
2011-09-30 |
2023-03-14 |
Teva Pharmaceuticals Australia Pty Ltd. |
Antibodies against tl1a and uses thereof
|
MX2014004074A
(es)
|
2011-10-05 |
2014-06-05 |
Genentech Inc |
Metodo de tratamiento de condiciones del higado utilizando antagonistas de notch2.
|
US9575073B2
(en)
|
2011-10-10 |
2017-02-21 |
Rutgers, The State University Of New Jersey |
Detection of high-risk intraductal papillary mucinous neoplasm and pancreatic adenocarcinoma
|
WO2013055998A1
(en)
|
2011-10-14 |
2013-04-18 |
Genentech, Inc. |
ANTI-HtrA1 ANTIBODIES AND METHODS OF USE
|
KR20140084164A
(ko)
|
2011-10-15 |
2014-07-04 |
제넨테크, 인크. |
암의 치료를 위한 scd1 길항제
|
WO2013059531A1
(en)
|
2011-10-20 |
2013-04-25 |
Genentech, Inc. |
Anti-gcgr antibodies and uses thereof
|
AR088513A1
(es)
|
2011-10-24 |
2014-06-18 |
Abbvie Inc |
Inmunoenlazantes dirigidos contra esclerostina
|
MX2014004981A
(es)
|
2011-10-24 |
2014-09-11 |
Abbvie Inc |
Inmunoaglutinantes dirigidos contra tnf.
|
US9655964B2
(en)
|
2011-10-24 |
2017-05-23 |
Abbvie Inc. |
Bispecific antibodies directed against TNF-α and IL-17
|
GB201118359D0
(en)
|
2011-10-25 |
2011-12-07 |
Univ Sheffield |
Pulmonary hypertension
|
SG10201603411WA
(en)
|
2011-10-28 |
2016-07-28 |
Teva Pharmaceuticals Australia Pty Ltd |
Polypeptide constructs and uses thereof
|
PE20142312A1
(es)
|
2011-10-28 |
2015-01-25 |
Genentech Inc |
Combinaciones terapeuticas y metodos para tratar el melanoma
|
CA2852709A1
(en)
|
2011-10-28 |
2013-05-02 |
Patrys Limited |
Pat-lm1 epitopes and methods for using same
|
GB201118840D0
(en)
|
2011-11-01 |
2011-12-14 |
Univ Sheffield |
Pulmonary hypertension II
|
PL2773671T3
(pl)
|
2011-11-04 |
2022-01-24 |
Zymeworks Inc. |
Projekt stabilnego przeciwciała heterodimerycznego z mutacjami w domenie fc
|
RU2014122602A
(ru)
|
2011-11-04 |
2015-12-10 |
Новартис Аг |
Конструкции на основе белка, родственного липопротеинам низкой плотности, 6(lrp6), и удлинителя полупериода существования
|
DK2776466T3
(da)
|
2011-11-11 |
2017-11-20 |
Ucb Biopharma Sprl |
Albuminbindende antistoffer og bindingsfragmenter deraf
|
WO2013078170A1
(en)
|
2011-11-21 |
2013-05-30 |
Genentech, Inc. |
Purification of anti-c-met antibodies
|
AU2012345926A1
(en)
|
2011-11-29 |
2014-05-29 |
Genentech, Inc. |
Compositions and methods for prostate cancer analysis
|
CA2857597A1
(en)
|
2011-11-30 |
2013-06-06 |
AbbVie Deutschland GmbH & Co. KG |
Methods and compositions for determining responsiveness to treatment with a tnf-alpha inhibitor
|
US20130251703A1
(en)
|
2011-12-05 |
2013-09-26 |
Novartis Ag |
Antibodies for epidermal growth factor receptor 3 (her3) directed to domain iii and domain iv of her3
|
WO2013084148A2
(en)
|
2011-12-05 |
2013-06-13 |
Novartis Ag |
Antibodies for epidermal growth factor receptor 3 (her3) directed to domain ii of her3
|
EP2788024A1
(en)
|
2011-12-06 |
2014-10-15 |
F.Hoffmann-La Roche Ag |
Antibody formulation
|
SG10201700169PA
(en)
|
2011-12-22 |
2017-02-27 |
Hoffmann La Roche |
Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides
|
CA3125875A1
(en)
|
2011-12-22 |
2013-06-27 |
F.Hoffmann-La Roche Ag |
Expression vector organization, novel production cell generation methods and their use for the recombinant production of polypeptides
|
WO2013096791A1
(en)
|
2011-12-23 |
2013-06-27 |
Genentech, Inc. |
Process for making high concentration protein formulations
|
AR089529A1
(es)
|
2011-12-30 |
2014-08-27 |
Abbvie Inc |
Proteinas de union especificas duales dirigidas contra il-13 y/o il-17
|
AU2013208003B2
(en)
|
2012-01-09 |
2017-12-14 |
The Scripps Research Institute |
Ultralong complementarity determining regions and uses thereof
|
CA2862979A1
(en)
|
2012-01-09 |
2013-07-18 |
The Scripps Research Institute |
Humanized antibodies with ultralong cdr3s
|
JP6247226B2
(ja)
|
2012-01-10 |
2017-12-13 |
バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. |
血液脳関門を越える治療分子の輸送の向上
|
KR20140119114A
(ko)
|
2012-01-18 |
2014-10-08 |
제넨테크, 인크. |
Fgf19 조절제의 사용 방법
|
PE20141561A1
(es)
|
2012-01-18 |
2014-11-12 |
Genentech Inc |
Anticuerpos anti-lrp5 y metodos de uso
|
WO2013112922A1
(en)
|
2012-01-27 |
2013-08-01 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
|
WO2013113641A1
(en)
|
2012-01-31 |
2013-08-08 |
Roche Glycart Ag |
Use of nkp46 as a predictive biomarker for cancer treatment with adcc- enhanced antibodies
|
BR112014019579A2
(pt)
|
2012-02-10 |
2019-10-15 |
Genentech, Inc |
Anticorpo de cadeia única, polinucleotídeo, vetor, célula hospedeira, método de produção de um anticorpo de cadeia única, heteromultímero e método de produção do heteromultímero
|
WO2013120056A1
(en)
|
2012-02-11 |
2013-08-15 |
Genentech, Inc. |
R-spondin translocations and methods using the same
|
ES2676031T3
(es)
|
2012-02-15 |
2018-07-16 |
F. Hoffmann-La Roche Ag |
Cromatografía de afinidad basada en el receptor Fc
|
GB201203071D0
(en)
|
2012-02-22 |
2012-04-04 |
Ucb Pharma Sa |
Biological products
|
GB201203587D0
(en)
|
2012-03-01 |
2012-04-11 |
Univ Warwick |
Modified bacterial cell
|
KR20140130455A
(ko)
|
2012-03-02 |
2014-11-10 |
로슈 글리카트 아게 |
Adcc-강화 항체를 사용한 암 치료용 예측 바이오마커
|
US9592289B2
(en)
|
2012-03-26 |
2017-03-14 |
Sanofi |
Stable IgG4 based binding agent formulations
|
BR112014024017A8
(pt)
|
2012-03-27 |
2017-07-25 |
Genentech Inc |
Métodos de tratamento de um tipo de câncer, de tratamento do carcinoma, para selecionar uma terapia e para quantificação e inibidor de her3
|
US10041950B2
(en)
|
2012-03-27 |
2018-08-07 |
Ventana Medical Systems, Inc. |
Signaling conjugates and methods of use
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
US9181572B2
(en)
|
2012-04-20 |
2015-11-10 |
Abbvie, Inc. |
Methods to modulate lysine variant distribution
|
US9067990B2
(en)
|
2013-03-14 |
2015-06-30 |
Abbvie, Inc. |
Protein purification using displacement chromatography
|
US9150645B2
(en)
|
2012-04-20 |
2015-10-06 |
Abbvie, Inc. |
Cell culture methods to reduce acidic species
|
JP6242865B2
(ja)
|
2012-05-01 |
2017-12-06 |
ジェネンテック, インコーポレイテッド |
抗pmel17抗体および免疫複合体
|
US9328174B2
(en)
|
2012-05-09 |
2016-05-03 |
Novartis Ag |
Chemokine receptor binding polypeptides
|
AU2013258834B2
(en)
|
2012-05-10 |
2017-09-07 |
Zymeworks Bc Inc. |
Heteromultimer constructs of immunoglobulin heavy chains with mutations in the Fc domain
|
WO2013170191A1
(en)
|
2012-05-11 |
2013-11-14 |
Genentech, Inc. |
Methods of using antagonists of nad biosynthesis from nicotinamide
|
WO2013173364A2
(en)
|
2012-05-14 |
2013-11-21 |
Biogen Idec Ma Inc. |
Lingo-2 antagonists for treatment of conditions involving motor neurons
|
AR091069A1
(es)
|
2012-05-18 |
2014-12-30 |
Amgen Inc |
Proteinas de union a antigeno dirigidas contra el receptor st2
|
EP2666786A1
(en)
|
2012-05-21 |
2013-11-27 |
PAION Deutschland GmbH |
Immunotherapy for intracranial hemorrhage
|
CN104335047B
(zh)
|
2012-05-23 |
2017-08-15 |
弗·哈夫曼-拉罗切有限公司 |
治疗剂的选择方法
|
US9249182B2
(en)
|
2012-05-24 |
2016-02-02 |
Abbvie, Inc. |
Purification of antibodies using hydrophobic interaction chromatography
|
SG11201408330XA
(en)
|
2012-05-24 |
2015-01-29 |
Mountgate Group Ltd |
Compositions and methods related to prevention and treatment of rabies infection
|
EP2861624A1
(en)
|
2012-06-15 |
2015-04-22 |
F. Hoffmann-La Roche AG |
Anti-pcsk9 antibodies, formulations, dosing, and methods of use
|
WO2014004586A1
(en)
|
2012-06-25 |
2014-01-03 |
Zymeworks Inc. |
Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
|
BR112014028368A2
(pt)
|
2012-06-27 |
2017-11-14 |
Hoffmann La Roche |
método de produção de conjugado de região fc de anticorpo, conjugado de região fc de anticorpo e formulação farmacêutica
|
ES2597228T3
(es)
|
2012-06-27 |
2017-01-17 |
F. Hoffmann-La Roche Ag |
Procedimiento para la selección y la producción de entidades de objetivación, como dianas, altamente selectivas y multiespecíficas, personalizadas, las cuales contienen por lo menos dos entidades de unión diferentes, y utilización de éstas
|
EP2867255B1
(en)
|
2012-06-27 |
2017-07-19 |
F. Hoffmann-La Roche AG |
Method for the selection and production of tailor-made, selective and multi-specific therapeutic molecules comprising at least two different targeting entities and uses thereof
|
BR112014029403A2
(pt)
|
2012-07-04 |
2018-10-09 |
F. Hoffmann-La Roche Ag |
conjugados, anticorpo e formulação farmacêutica
|
EP3339328A1
(en)
|
2012-07-04 |
2018-06-27 |
F. Hoffmann-La Roche AG |
Anti-biotin antibodies and methods of use
|
EP2869837B1
(en)
|
2012-07-04 |
2016-09-14 |
F. Hoffmann-La Roche AG |
Anti-theophylline antibodies and methods of use
|
RU2670491C2
(ru)
|
2012-07-05 |
2018-10-23 |
Дженентек, Инк. |
Система экспрессии и секреции
|
EP2869847B1
(en)
|
2012-07-09 |
2017-12-06 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd79b antibodies
|
MX2015000357A
(es)
|
2012-07-09 |
2015-05-12 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-cd22.
|
BR112015000439A2
(pt)
|
2012-07-09 |
2017-12-19 |
Genentech Inc |
imunoconjugado , formulação farmacêutica e métodos de tratamento de um indivíduo e de inibição da proliferação
|
IN2014DN10652A
(es)
|
2012-07-09 |
2015-09-11 |
Genentech Inc |
|
AR091755A1
(es)
|
2012-07-12 |
2015-02-25 |
Abbvie Inc |
Proteinas de union a il-1
|
IN2014DN11157A
(es)
|
2012-07-13 |
2015-10-02 |
Roche Glycart Ag |
|
CN112587658A
(zh)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
GB201213652D0
(en)
|
2012-08-01 |
2012-09-12 |
Oxford Biotherapeutics Ltd |
Therapeutic and diagnostic target
|
NZ702241A
(en)
|
2012-08-07 |
2018-04-27 |
Roche Glycart Ag |
Composition comprising two antibodies engineered to have reduced and increased effector function
|
JP2015530983A
(ja)
|
2012-08-08 |
2015-10-29 |
ロシュ グリクアート アーゲー |
インターロイキン−10融合タンパク質及びその使用
|
WO2014023709A1
(en)
|
2012-08-09 |
2014-02-13 |
Roche Glycart Ag |
Asgpr antibodies and uses thereof
|
KR20150043523A
(ko)
|
2012-09-02 |
2015-04-22 |
애브비 인코포레이티드 |
단백질 불균일성의 제어 방법
|
US9512214B2
(en)
|
2012-09-02 |
2016-12-06 |
Abbvie, Inc. |
Methods to control protein heterogeneity
|
RU2015117393A
(ru)
|
2012-10-08 |
2016-12-10 |
Роше Гликарт Аг |
Лишенные fc антитела, содержащие два Fab-фрагмента, и способы их применения
|
ES2822135T3
(es)
|
2012-10-18 |
2021-04-29 |
Univ Rockefeller |
Anticuerpos anti-VIH ampliamente neutralizantes
|
US9688741B2
(en)
|
2012-10-23 |
2017-06-27 |
Elastagen Pty Ltd |
Elastic hydrogel
|
MY171664A
(en)
|
2012-11-01 |
2019-10-22 |
Abbvie Inc |
Anti-dll4/vegf dual variable domain immunoglobulins and uses thereof
|
WO2014071358A2
(en)
|
2012-11-05 |
2014-05-08 |
Foundation Medicine, Inc. |
Novel ntrk1 fusion molecules and uses thereof
|
JP6302476B2
(ja)
|
2012-11-08 |
2018-03-28 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
Her3のベータヘアピンに結合するher3抗原結合タンパク質
|
TWI657095B
(zh)
|
2012-11-13 |
2019-04-21 |
美商建南德克公司 |
抗血球凝集素抗體及使用方法
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
EP2928512B1
(en)
|
2012-12-10 |
2018-08-15 |
Elastagen Pty Ltd |
Scalable three-dimensional elastic construct manufacturing
|
WO2014100542A1
(en)
|
2012-12-21 |
2014-06-26 |
Abbvie, Inc. |
High-throughput antibody humanization
|
EP2938637A2
(en)
|
2012-12-28 |
2015-11-04 |
AbbVie Inc. |
Multivalent binding protein compositions
|
AU2014207342C1
(en)
|
2013-01-18 |
2019-04-04 |
Foundation Medicine, Inc. |
Methods of treating cholangiocarcinoma
|
EP2948177A1
(en)
|
2013-01-22 |
2015-12-02 |
AbbVie Inc. |
Methods for optimizing domain stability of binding proteins
|
WO2014116846A2
(en)
|
2013-01-23 |
2014-07-31 |
Abbvie, Inc. |
Methods and compositions for modulating an immune response
|
WO2014114595A1
(en)
|
2013-01-23 |
2014-07-31 |
Roche Glycart Ag |
Predictive biomarker for cancer treatment with adcc-enhanced antibodies
|
WO2014116749A1
(en)
|
2013-01-23 |
2014-07-31 |
Genentech, Inc. |
Anti-hcv antibodies and methods of using thereof
|
US9920121B2
(en)
|
2013-01-25 |
2018-03-20 |
Amgen Inc. |
Antibodies targeting CDH19 for melanoma
|
WO2014117220A1
(en)
|
2013-02-01 |
2014-08-07 |
Transbio Ltd |
Anti-cd83 antibodies and use thereof
|
ES2942636T3
(es)
|
2013-02-07 |
2023-06-05 |
Csl Ltd |
Proteínas de unión a IL-11R y usos de las mismas
|
US20140228875A1
(en)
|
2013-02-08 |
2014-08-14 |
Nidus Medical, Llc |
Surgical device with integrated visualization and cauterization
|
GB201302447D0
(en)
|
2013-02-12 |
2013-03-27 |
Oxford Biotherapeutics Ltd |
Therapeutic and diagnostic target
|
MX2015010791A
(es)
|
2013-02-22 |
2015-11-26 |
Hoffmann La Roche |
Metodos para tratar el cancer y prevenir la resistencia a farmacos.
|
RU2015140915A
(ru)
|
2013-02-26 |
2017-04-03 |
Роше Гликарт Аг |
Биспецифические антигенсвязывающие молекулы, активирующие т-клетки
|
KR20210094673A
(ko)
|
2013-02-26 |
2021-07-29 |
로슈 글리카트 아게 |
이중특이적 t 세포 활성화 항원 결합 분자
|
EP2961770A1
(en)
|
2013-02-26 |
2016-01-06 |
Roche Glycart AG |
Bispecific t cell activating antigen binding molecules
|
MX2015010789A
(es)
|
2013-02-26 |
2015-11-26 |
Roche Glycart Ag |
Anticuerpos anti-pcsm.
|
WO2014133855A1
(en)
|
2013-02-28 |
2014-09-04 |
Caprion Proteomics Inc. |
Tuberculosis biomarkers and uses thereof
|
US9925240B2
(en)
|
2013-03-06 |
2018-03-27 |
Genentech, Inc. |
Methods of treating and preventing cancer drug resistance
|
CA2905010A1
(en)
|
2013-03-12 |
2014-09-18 |
Abbvie Inc. |
Human antibodies that bind human tnf-alpha and methods of preparing the same
|
CA2906057A1
(en)
|
2013-03-13 |
2014-10-02 |
Genentech, Inc. |
Antibody formulations
|
CA3113172A1
(en)
|
2013-03-13 |
2014-10-02 |
Genentech, Inc. |
Screen for compound that prevents protein oxidation based on comparison with l-tryptophan
|
RU2707550C2
(ru)
|
2013-03-13 |
2019-11-27 |
Дженентек, Инк. |
Составы со сниженным окислением
|
PL2968494T3
(pl)
|
2013-03-13 |
2019-04-30 |
Seattle Genetics Inc |
Filtracja z węglem aktywnym do oczyszczania benzodiazepinowych ADC
|
US10653779B2
(en)
|
2013-03-13 |
2020-05-19 |
Genentech, Inc. |
Formulations with reduced oxidation
|
AR095398A1
(es)
|
2013-03-13 |
2015-10-14 |
Genentech Inc |
Formulaciones con oxidación reducida
|
EP2970479B1
(en)
|
2013-03-14 |
2019-04-24 |
Novartis AG |
Antibodies against notch 3
|
US9017687B1
(en)
|
2013-10-18 |
2015-04-28 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same using displacement chromatography
|
EP3564384A1
(en)
|
2013-03-14 |
2019-11-06 |
Abbott Laboratories |
Hcv core lipid binding domain monoclonal antibodies
|
US9499614B2
(en)
|
2013-03-14 |
2016-11-22 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
|
RU2015139054A
(ru)
|
2013-03-14 |
2017-04-19 |
Дженентек, Инк. |
Способы лечения рака и профилактики лекарственной резистентности рака
|
WO2014158272A1
(en)
|
2013-03-14 |
2014-10-02 |
Abbott Laboratories |
Hcv antigen-antibody combination assay and methods and compositions for use therein
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
PE20151672A1
(es)
|
2013-03-14 |
2015-11-27 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-b7-h4
|
JP2016512241A
(ja)
|
2013-03-14 |
2016-04-25 |
アボット・ラボラトリーズAbbott Laboratories |
改良された抗体検出のためのhcvns3組換え抗原およびこの突然変異体
|
WO2014159579A1
(en)
|
2013-03-14 |
2014-10-02 |
Abbvie Inc. |
MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
|
EP2968540A2
(en)
|
2013-03-14 |
2016-01-20 |
Genentech, Inc. |
Combinations of a mek inhibitor compound with an her3/egfr inhibitor compound and methods of use
|
JP2016517441A
(ja)
|
2013-03-15 |
2016-06-16 |
ジェネンテック, インコーポレイテッド |
抗CRTh2抗体及び使用方法
|
SG10201701380TA
(en)
|
2013-03-15 |
2017-04-27 |
Genentech Inc |
Biomarkers and methods of treating pd-1 and pd-l1 related conditions
|
PL2970875T3
(pl)
|
2013-03-15 |
2020-08-10 |
F.Hoffmann-La Roche Ag |
Kompozycje do hodowli komórkowych z przeciwutleniaczami i sposoby wytwarzania polipeptydów
|
CA2905123A1
(en)
|
2013-03-15 |
2014-09-18 |
Genentech, Inc. |
Methods of treating cancer and preventing cancer drug resistance
|
US11634502B2
(en)
|
2013-03-15 |
2023-04-25 |
Amgen Inc. |
Heterodimeric bispecific antibodies
|
SG10201706210WA
(en)
|
2013-03-15 |
2017-09-28 |
Genentech Inc |
Compositions and methods for diagnosis and treatment of hepatic cancers
|
BR112015022529A2
(pt)
|
2013-03-15 |
2017-07-18 |
Genentech Inc |
meios de cultura de células e processos de produção de anticorpo
|
EA038918B1
(ru)
|
2013-03-15 |
2021-11-09 |
Зинджения, Инк. |
Пептид, связывающий рецептор эпидермального фактора роста, мультиспецифические комплексы, содержащие пептид и антитела, и их применение
|
TWI689313B
(zh)
|
2013-03-15 |
2020-04-01 |
德商艾伯維德國有限及兩合公司 |
抗-egfr抗體藥物結合物調配物
|
CA2904448A1
(en)
|
2013-03-15 |
2014-09-18 |
Tariq Ghayur |
Dual specific binding proteins directed against il-1.beta. and/or il-17
|
US10993420B2
(en)
|
2013-03-15 |
2021-05-04 |
Erasmus University Medical Center |
Production of heavy chain only antibodies in transgenic mammals
|
US20140286968A1
(en)
|
2013-03-15 |
2014-09-25 |
Abbvie Inc. |
Antibody drug conjugate (adc) purification
|
US20140302037A1
(en)
|
2013-03-15 |
2014-10-09 |
Amgen Inc. |
BISPECIFIC-Fc MOLECULES
|
WO2014150877A2
(en)
|
2013-03-15 |
2014-09-25 |
Ac Immune S.A. |
Anti-tau antibodies and methods of use
|
GB201306589D0
(en)
|
2013-04-11 |
2013-05-29 |
Abeterno Ltd |
Live cell imaging
|
US11117975B2
(en)
|
2013-04-29 |
2021-09-14 |
Teva Pharmaceuticals Australia Pty Ltd |
Anti-CD38 antibodies and fusions to attenuated interferon alpha-2B
|
BR112015027313A2
(pt)
|
2013-04-29 |
2017-09-26 |
Teva Pharmaceuticals Australia Pty Ltd |
anticorpos anti-cd38 e fusões ao interferon alfa-2b atenuado
|
CN105358698B
(zh)
|
2013-04-29 |
2024-02-20 |
生物催化公司 |
包含结合至鞘脂的抗体的农用化学组合物
|
KR102293064B1
(ko)
|
2013-05-20 |
2021-08-23 |
제넨테크, 인크. |
항-트랜스페린 수용체 항체 및 사용 방법
|
CN118271441A
(zh)
|
2013-05-30 |
2024-07-02 |
基尼克萨制药有限公司 |
制瘤素m受体抗原结合蛋白
|
WO2015017146A2
(en)
|
2013-07-18 |
2015-02-05 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
US10640574B2
(en)
|
2013-07-18 |
2020-05-05 |
Taurus Biosciences, Llc |
Humanized antibodies with ultralong complementary determining regions
|
EP3024922A4
(en)
|
2013-07-23 |
2017-03-29 |
Biocon Limited |
Methods for controlling fucosylation levels in proteins
|
CN113683695A
(zh)
|
2013-08-02 |
2021-11-23 |
辉瑞公司 |
抗cxcr4抗体及抗体-药物缀合物
|
WO2015021508A1
(en)
|
2013-08-13 |
2015-02-19 |
The University Of Sydney |
Regeneration of damaged tissue
|
AR097685A1
(es)
|
2013-09-17 |
2016-04-06 |
Genentech Inc |
Métodos de uso de anticuerpos anti-lgr5
|
SG10201708542RA
(en)
|
2013-09-27 |
2017-12-28 |
Genentech Inc |
Anti-pdl1 antibody formulations
|
WO2015050959A1
(en)
|
2013-10-01 |
2015-04-09 |
Yale University |
Anti-kit antibodies and methods of use thereof
|
CN118005782A
(zh)
|
2013-10-02 |
2024-05-10 |
免疫医疗有限责任公司 |
中和抗甲型流感抗体及其用途
|
EP3052640A2
(en)
|
2013-10-04 |
2016-08-10 |
AbbVie Inc. |
Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
|
KR20160044060A
(ko)
|
2013-10-11 |
2016-04-22 |
에프. 호프만-라 로슈 아게 |
다중특이적 도메인 교환된 통상의 가변 경쇄 항체
|
KR20160068855A
(ko)
|
2013-10-11 |
2016-06-15 |
제넨테크, 인크. |
Nsp4 억제제 및 사용 방법
|
WO2015058132A2
(en)
|
2013-10-18 |
2015-04-23 |
Genentech, Inc. |
Anti-rspo antibodies and methods of use
|
US9085618B2
(en)
|
2013-10-18 |
2015-07-21 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same
|
US9181337B2
(en)
|
2013-10-18 |
2015-11-10 |
Abbvie, Inc. |
Modulated lysine variant species compositions and methods for producing and using the same
|
US8946395B1
(en)
|
2013-10-18 |
2015-02-03 |
Abbvie Inc. |
Purification of proteins using hydrophobic interaction chromatography
|
AU2014340129A1
(en)
|
2013-10-23 |
2016-05-26 |
Genentech, Inc. |
Methods of diagnosing and treating eosinophilic disorders
|
EP3069137A1
(en)
|
2013-11-05 |
2016-09-21 |
Novartis Ag |
Organic compounds
|
WO2015073884A2
(en)
|
2013-11-15 |
2015-05-21 |
Abbvie, Inc. |
Glycoengineered binding protein compositions
|
CN111499743B
(zh)
|
2013-11-21 |
2024-01-12 |
豪夫迈·罗氏有限公司 |
抗-α-突触核蛋白抗体及使用方法
|
CA2931356A1
(en)
|
2013-11-27 |
2015-06-04 |
Zymeworks Inc. |
Bispecific antigen-binding constructs targeting her2
|
EP3074038B1
(en)
|
2013-11-28 |
2019-01-02 |
CSL Limited |
Method of treating diabetic nephropathy
|
JP2016540761A
(ja)
|
2013-12-02 |
2016-12-28 |
アッヴィ・インコーポレイテッド |
変形性関節症を治療するための組成物及び方法
|
US9309314B2
(en)
|
2013-12-03 |
2016-04-12 |
Agency For Science, Technology And Research (A*Star) |
Polypeptides, nucleic acids and uses thereof
|
SG10201808835QA
(en)
|
2013-12-09 |
2018-11-29 |
Allakos Inc |
Anti-siglec-8 antibodies and methods of use thereof
|
EA201691214A1
(ru)
|
2013-12-13 |
2016-12-30 |
Дженентек, Инк. |
Антитела к cd33 и иммуноконъюгаты
|
EP2883883A1
(en)
|
2013-12-16 |
2015-06-17 |
Cardio3 Biosciences S.A. |
Therapeutic targets and agents useful in treating ischemia reperfusion injury
|
HUE047699T2
(hu)
|
2013-12-17 |
2020-05-28 |
Hoffmann La Roche |
Eljárások rákbetegségek kezelésére PD-1-tengelyhez kötõdõ antagonisták és taxánok alkalmazásával
|
US20150190506A1
(en)
|
2013-12-17 |
2015-07-09 |
Genentech, Inc. |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
WO2015095392A1
(en)
|
2013-12-17 |
2015-06-25 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
CN105899535A
(zh)
|
2013-12-17 |
2016-08-24 |
豪夫迈·罗氏有限公司 |
用pd-1轴结合拮抗剂和抗cd20抗体治疗癌症的方法
|
JP6553618B2
(ja)
|
2013-12-18 |
2019-07-31 |
シーエスエル リミティド |
創傷を治療する方法
|
PT3083680T
(pt)
|
2013-12-20 |
2020-03-17 |
Hoffmann La Roche |
Anticorpos humanizados anti-tau(ps422) e métodos de utilização
|
TWI728373B
(zh)
|
2013-12-23 |
2021-05-21 |
美商建南德克公司 |
抗體及使用方法
|
CN105873615B
(zh)
|
2014-01-03 |
2020-12-25 |
豪夫迈·罗氏有限公司 |
共价连接的helicar-抗helicar抗体缀合物及其用途
|
BR112016013849A2
(pt)
|
2014-01-03 |
2017-10-10 |
Hoffmann La Roche |
conjugados de anticorpos biespecíficos antihapteno/antirreceptores da barreira hematoencefálica, seus usos, e formulação farmacêutica
|
JP6521464B2
(ja)
|
2014-01-03 |
2019-05-29 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
共有結合で連結されたポリペプチド毒素−抗体コンジュゲート
|
JP6557664B2
(ja)
|
2014-01-06 |
2019-08-07 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
一価の血液脳関門シャトルモジュール
|
SG11201605296SA
(en)
|
2014-01-10 |
2016-07-28 |
Birdie Biopharmaceuticals Inc |
Compounds and compositions for treating her2 positive tumors
|
KR20160111469A
(ko)
|
2014-01-24 |
2016-09-26 |
제넨테크, 인크. |
항-steap1 항체 및 면역접합체를 사용하는 방법
|
ES2694857T3
(es)
|
2014-02-04 |
2018-12-27 |
Genentech, Inc. |
Smoothened mutante y métodos de uso de la misma
|
ES2873248T3
(es)
|
2014-02-08 |
2021-11-03 |
Hoffmann La Roche |
Métodos para tratar la enfermedad de Alzheimer
|
KR20160111039A
(ko)
|
2014-02-08 |
2016-09-23 |
제넨테크, 인크. |
알츠하이머 질환을 치료하는 방법
|
RS57608B1
(sr)
|
2014-02-12 |
2018-11-30 |
Hoffmann La Roche |
Anti-jagged1 antitela i načini primene
|
RU2019119862A
(ru)
|
2014-02-20 |
2019-07-15 |
Аллерган, Инк. |
Антитела к компоненту комплемента c5
|
CR20160379A
(es)
|
2014-02-21 |
2016-10-07 |
Genentech Inc |
Anticuerpos biespecificos anti-il 13/il-17 y sus usos
|
RU2673036C2
(ru)
|
2014-02-27 |
2018-11-21 |
Аллерган, Инк. |
АНТИТЕЛА К ФАКТОРУ КОМПЛЕМЕНТА Bb
|
JP6825909B2
(ja)
|
2014-02-28 |
2021-02-03 |
アラコス インコーポレイテッド |
シグレック−8関連疾患を処置するための方法および組成物
|
HRP20211748T1
(hr)
|
2014-03-14 |
2022-02-18 |
F. Hoffmann - La Roche Ag |
Postupci i sastavi za sekreciju heterolognih polipeptida
|
WO2015140591A1
(en)
|
2014-03-21 |
2015-09-24 |
Nordlandssykehuset Hf |
Anti-cd14 antibodies and uses thereof
|
SG10201808837RA
(en)
|
2014-03-21 |
2018-11-29 |
Abbvie Inc |
Anti-egfr antibodies and antibody drug conjugates
|
JP2017516458A
(ja)
|
2014-03-24 |
2017-06-22 |
ジェネンテック, インコーポレイテッド |
c−met拮抗剤による癌治療及びc−met拮抗剤のHGF発現との相関
|
CN106132439A
(zh)
|
2014-03-31 |
2016-11-16 |
豪夫迈·罗氏有限公司 |
包含抗血管发生剂和ox40结合激动剂的组合疗法
|
BR112016022658A2
(pt)
|
2014-03-31 |
2017-10-17 |
Genentech Inc |
anticorpos anti-ox40 e métodos de uso
|
WO2015161220A1
(en)
|
2014-04-18 |
2015-10-22 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating sickle-cell disease
|
WO2015164615A1
(en)
|
2014-04-24 |
2015-10-29 |
University Of Oslo |
Anti-gluten antibodies and uses thereof
|
UA119352C2
(uk)
|
2014-05-01 |
2019-06-10 |
Тева Фармасьютикалз Острейліа Пті Лтд |
Комбінація леналідоміду або помалідоміду і конструкції анти-cd38 антитіло-атенуйований інтерферон альфа-2b та спосіб лікування суб'єкта, який має cd38-експресуючу пухлину
|
DK3140653T3
(da)
|
2014-05-08 |
2022-06-20 |
Novodiax Inc |
Direkte immunhistokemianalyse
|
CN106413750B
(zh)
|
2014-05-16 |
2022-04-29 |
免疫医疗有限责任公司 |
具有增强的治疗和诊断特性的带有改变的新生儿Fc受体结合的分子
|
CA2946662A1
(en)
|
2014-05-22 |
2015-11-26 |
Genentech, Inc. |
Anti-gpc3 antibodies and immunoconjugates
|
WO2015179835A2
(en)
|
2014-05-23 |
2015-11-26 |
Genentech, Inc. |
Mit biomarkers and methods using the same
|
WO2015191568A2
(en)
|
2014-06-09 |
2015-12-17 |
Biomed Valley Discoveries, Inc. |
Combination therapies using agents that target tumor-associated stroma or tumor cells and tumor vasculature
|
US10799584B2
(en)
|
2014-06-09 |
2020-10-13 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services National Institutes Of Health |
Combination therapies using agents that target tumor-associated stroma or tumor cells and alkylating agents
|
WO2015191596A1
(en)
|
2014-06-09 |
2015-12-17 |
Biomed Valley Discoveries, Inc. |
Combination therapies using platinum agents and agents that target tumor-associated stroma or tumor cells
|
US10758613B2
(en)
|
2014-06-09 |
2020-09-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services National Intstitutes Of Health |
Combination therapies using anti-metabolites and agents that target tumor-associated stroma or tumor cells
|
WO2015191610A2
(en)
|
2014-06-09 |
2015-12-17 |
Biomed Valley Discoveries, Inc. |
Combination therapies using agents that target tumor-associated stroma or tumor cells and other pathways
|
WO2015191583A2
(en)
|
2014-06-09 |
2015-12-17 |
Biomed Valley Discoveries, Inc. |
Combination therapies targeting tumor-associated stroma or tumor cells and topoisomerase
|
WO2015191590A2
(en)
|
2014-06-09 |
2015-12-17 |
Biomed Valley Discoveries, Inc. |
Combination therapies targeting tumor-associated stroma or tumor cells and microtubules
|
KR20170010785A
(ko)
|
2014-06-11 |
2017-02-01 |
제넨테크, 인크. |
항-lgr5 항체 및 이의 용도
|
US20230190750A1
(en)
|
2014-06-13 |
2023-06-22 |
Genentech, Inc. |
Methods of treating and preventing cancer drug resistance
|
EP3154566B1
(en)
|
2014-06-13 |
2022-08-03 |
Acceleron Pharma Inc. |
Actrii antagonist for the treatment or prevention of a cutaneous ulcer in a subject that has anemia
|
NL2013007B1
(en)
|
2014-06-16 |
2016-07-05 |
Ablynx Nv |
Methods of treating TTP with immunoglobulin single variable domains and uses thereof.
|
NL2013661B1
(en)
|
2014-10-21 |
2016-10-05 |
Ablynx Nv |
KV1.3 Binding immunoglobulins.
|
BR112016029935A2
(pt)
|
2014-06-26 |
2017-10-31 |
Hoffmann La Roche |
?anticorpos anti-brdu, complexo, formulação farmacêutica e uso de anticorpo?
|
AR100978A1
(es)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
|
CN113789339A
(zh)
|
2014-07-03 |
2021-12-14 |
豪夫迈·罗氏有限公司 |
多肽表达系统
|
CN112546230A
(zh)
|
2014-07-09 |
2021-03-26 |
博笛生物科技有限公司 |
用于治疗癌症的联合治疗组合物和联合治疗方法
|
EP3166976B1
(en)
|
2014-07-09 |
2022-02-23 |
Birdie Biopharmaceuticals Inc. |
Anti-pd-l1 combinations for treating tumors
|
US9914774B2
(en)
|
2014-07-11 |
2018-03-13 |
Genentech, Inc. |
Notch pathway inhibition
|
US20160009805A1
(en)
|
2014-07-11 |
2016-01-14 |
Genentech, Inc. |
Anti-pd-l1 antibodies and diagnostic uses thereof
|
CA2951984C
(en)
|
2014-07-15 |
2023-10-03 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Isolated polypeptides of cd44 and uses thereof
|
WO2016020309A1
(en)
|
2014-08-04 |
2016-02-11 |
F. Hoffmann-La Roche Ag |
Bispecific t cell activating antigen binding molecules
|
CA2959141A1
(en)
|
2014-08-28 |
2016-03-03 |
Bioatla, Llc |
Conditionally active chimeric antigen receptors for modified t-cells
|
CN112546238A
(zh)
|
2014-09-01 |
2021-03-26 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
JP6943760B2
(ja)
|
2014-09-12 |
2021-10-06 |
ジェネンテック, インコーポレイテッド |
抗b7−h4抗体及び免疫複合体
|
EA201790545A1
(ru)
|
2014-09-12 |
2017-07-31 |
Дженентек, Инк. |
Антитела и иммуноконъюгаты против her2
|
EP3693391A1
(en)
|
2014-09-12 |
2020-08-12 |
Genentech, Inc. |
Anti-cll-1 antibodies and immunoconjugates
|
EP3193932B1
(en)
|
2014-09-15 |
2023-04-26 |
F. Hoffmann-La Roche AG |
Antibody formulations
|
MX2017003472A
(es)
|
2014-09-17 |
2017-10-31 |
Genentech Inc |
Inmunoconjugados que comprenden anticuerpos anti-her2.
|
DK3262071T3
(da)
|
2014-09-23 |
2020-06-15 |
Hoffmann La Roche |
Fremgangsmåde til anvendelse af anti-CD79b-immunkonjugater
|
CA2963030C
(en)
|
2014-10-10 |
2021-07-13 |
Vectura Gmbh |
Inhalation device for use in aerosol therapy of respiratory diseases
|
EP3204041A1
(en)
|
2014-10-10 |
2017-08-16 |
Ablynx N.V. |
Methods of treating rsv infections
|
WO2016059602A2
(en)
|
2014-10-16 |
2016-04-21 |
Glaxo Group Limited |
Methods of treating cancer and related compositions
|
JP2017536102A
(ja)
|
2014-10-16 |
2017-12-07 |
ジェネンテック, インコーポレイテッド |
抗アルファ−シヌクレイン抗体及び使用方法
|
AU2015336946A1
(en)
|
2014-10-23 |
2017-04-13 |
La Trobe University |
Fn14-binding proteins and uses thereof
|
WO2016061617A1
(en)
|
2014-10-23 |
2016-04-28 |
Dendrocyte Biotech Pty Ltd |
Cd83 binding proteins and uses thereof
|
CA2965414C
(en)
|
2014-10-29 |
2024-01-09 |
Teva Pharmaceuticals Australia Pty Ltd |
Interferon .alpha.2.beta. variants
|
PL3212230T3
(pl)
|
2014-10-29 |
2021-07-26 |
Seagen Inc. |
Dawkowanie i podawanie niefukozylowanych przeciwciał anty-CD40
|
BR112017009151A2
(pt)
|
2014-11-03 |
2018-03-06 |
Genentech, Inc. |
ensaios para detectar subgrupos imunológicos de célula t e métodos de uso dos mesmos
|
SG11201703521UA
(en)
|
2014-11-03 |
2017-05-30 |
Genentech Inc |
Methods and biomarkers for predicting efficacy and evaluation of an ox40 agonist treatment
|
EP3215624B1
(en)
|
2014-11-05 |
2023-11-29 |
Biotalys NV |
Transgenic plant comprising a polynucleotide encoding a variable domain of heavy-chain antibody
|
RU2739500C2
(ru)
|
2014-11-05 |
2020-12-25 |
Дженентек, Инк. |
Способы получения двуцепочечных белков в бактериях
|
JP6875276B2
(ja)
|
2014-11-05 |
2021-05-19 |
ジェネンテック, インコーポレイテッド |
細菌における2鎖タンパク質の生成方法
|
WO2016073157A1
(en)
|
2014-11-06 |
2016-05-12 |
Genentech, Inc. |
Anti-ang2 antibodies and methods of use thereof
|
KR20170072343A
(ko)
|
2014-11-06 |
2017-06-26 |
제넨테크, 인크. |
Ox40 결합 효능제 및 tigit 억제제를 포함하는 병용 요법
|
BR112017009728A2
(pt)
|
2014-11-10 |
2018-02-06 |
Genentech, Inc. |
anticorpos isolados, ácido nucleico isolado, vetor, célula hospedeira, método para produzir o anticorpo, composição, usos de um anticorpo e métodos de tratamento de um distúrbio
|
EP3217787B1
(en)
|
2014-11-10 |
2019-04-17 |
F.Hoffmann-La Roche Ag |
Animal model for nephropathy and agents for treating the same
|
MX2017006250A
(es)
|
2014-11-14 |
2017-11-17 |
Hoffmann La Roche |
Moleculas de union a antigeno que comprenden un trimero de ligando de la familia de tnf.
|
MX2017006320A
(es)
|
2014-11-17 |
2017-08-10 |
Genentech Inc |
Terapia combinada que comprende agonistas de unión de ox40 y antagonistas de unión del eje de pd-1.
|
WO2016081440A1
(en)
|
2014-11-17 |
2016-05-26 |
Carnegie Mellon University |
Activatable two-component photosensitizers
|
US11008403B2
(en)
|
2014-11-19 |
2021-05-18 |
Genentech, Inc. |
Anti-transferrin receptor / anti-BACE1 multispecific antibodies and methods of use
|
EP3221364B1
(en)
|
2014-11-19 |
2020-12-16 |
Genentech, Inc. |
Antibodies against bace1 and use thereof for neural disease immunotherapy
|
US10508151B2
(en)
|
2014-11-19 |
2019-12-17 |
Genentech, Inc. |
Anti-transferrin receptor antibodies and methods of use
|
RU2747011C2
(ru)
|
2014-11-20 |
2021-04-23 |
Ф.Хоффманн-Ля Рош Аг |
Общие легкие цепи и способы их применения
|
HUE052831T2
(hu)
|
2014-11-20 |
2021-05-28 |
Hoffmann La Roche |
T-sejteket aktiváló bispecifikus antigén kötõ CD3 molekulák, 1. folát receptor (FolR1) és PD-1 tengelyt célzó antagonisták kombinált terápiája
|
MA41119A
(fr)
|
2014-12-03 |
2017-10-10 |
Acceleron Pharma Inc |
Méthodes de traitement de syndromes myélodysplasiques et d'anémie sidéroblastique
|
WO2016087416A1
(en)
|
2014-12-03 |
2016-06-09 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
TWI713480B
(zh)
|
2014-12-05 |
2020-12-21 |
美商建南德克公司 |
抗CD79b抗體及其使用方法
|
JP2018502840A
(ja)
|
2014-12-10 |
2018-02-01 |
ジェネンテック, インコーポレイテッド |
血液脳関門受容体抗体及び使用方法
|
WO2016094881A2
(en)
|
2014-12-11 |
2016-06-16 |
Abbvie Inc. |
Lrp-8 binding proteins
|
SG10201710322VA
(en)
|
2014-12-19 |
2018-02-27 |
Chugai Pharmaceutical Co Ltd |
Anti-c5 antibodies and methods of use
|
EP3233910B1
(en)
|
2014-12-19 |
2019-12-11 |
Ablynx N.V. |
Cysteine linked nanobody dimers
|
EP3233120A4
(en)
|
2014-12-19 |
2018-05-30 |
Monash University |
Il-21 antibodies
|
US10435467B2
(en)
|
2015-01-08 |
2019-10-08 |
Biogen Ma Inc. |
LINGO-1 antagonists and uses for treatment of demyelinating disorders
|
HRP20220860T1
(hr)
|
2015-01-09 |
2022-10-14 |
Adalta Limited |
Cxcr4 vezujuće molekule
|
EP3247723A1
(en)
|
2015-01-22 |
2017-11-29 |
Chugai Seiyaku Kabushiki Kaisha |
A combination of two or more anti-c5 antibodies and methods of use
|
CA2974377C
(en)
|
2015-01-23 |
2023-08-01 |
The University Of North Carolina At Chapel Hill |
Apparatuses, systems, and methods for preclinical ultrasound imaging of subjects
|
EP3253791A1
(en)
|
2015-02-03 |
2017-12-13 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Anti-rho gtpase conformational single domain antibodies and uses thereof
|
CA2975875A1
(en)
|
2015-02-04 |
2016-08-11 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
EA201791754A1
(ru)
|
2015-02-05 |
2019-01-31 |
Чугаи Сейяку Кабусики Кайся |
АНТИТЕЛА, СОДЕРЖАЩИЕ ЗАВИСЯЩИЙ ОТ КОНЦЕНТРАЦИИ ИОНОВ АНТИГЕНСВЯЗЫВАЮЩИЙ ДОМЕН, ВАРИАНТЫ Fc-ОБЛАСТИ, IL-8-СВЯЗЫВАЮЩИЕ АНТИТЕЛА И ИХ ПРИМЕНЕНИЯ
|
AU2016219511B2
(en)
|
2015-02-09 |
2020-11-12 |
Research Development Foundation |
Engineered immunoglobulin Fc polypeptides displaying improved complement activation
|
US20170151281A1
(en)
|
2015-02-19 |
2017-06-01 |
Batu Biologics, Inc. |
Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
|
WO2016135041A1
(en)
|
2015-02-26 |
2016-09-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Fusion proteins and antibodies comprising thereof for promoting apoptosis
|
WO2016149276A1
(en)
|
2015-03-16 |
2016-09-22 |
Genentech, Inc. |
Methods of detecting and quantifying il-13 and uses in diagnosing and treating th2-associated diseases
|
WO2016146833A1
(en)
|
2015-03-19 |
2016-09-22 |
F. Hoffmann-La Roche Ag |
Biomarkers for nad(+)-diphthamide adp ribosyltransferase resistance
|
WO2016164089A2
(en)
|
2015-04-06 |
2016-10-13 |
Acceleron Pharma Inc. |
Tgf-beta superfamily type i and type ii receptor heteromultimers and uses thereof
|
MA41919A
(fr)
|
2015-04-06 |
2018-02-13 |
Acceleron Pharma Inc |
Hétéromultimères alk4:actriib et leurs utilisations
|
AU2016245807B2
(en)
|
2015-04-07 |
2022-05-19 |
Alector Llc |
Anti-sortilin antibodies and methods of use thereof
|
CN107709364A
(zh)
|
2015-04-07 |
2018-02-16 |
豪夫迈·罗氏有限公司 |
具有激动剂活性的抗原结合复合体及使用方法
|
EP3286565A1
(en)
|
2015-04-21 |
2018-02-28 |
Genentech, Inc. |
Compositions and methods for prostate cancer analysis
|
EP3913052A1
(en)
|
2015-04-24 |
2021-11-24 |
F. Hoffmann-La Roche AG |
Methods of identifying bacteria comprising binding polypeptides
|
MX2017013807A
(es)
|
2015-04-30 |
2018-03-15 |
Harvard College |
Anticuerpos anti-proteina de union al lipido de adipocito humana (ap2) y agente de union al antigeno para tratar trastornos metabolicos.
|
EP3288981A1
(en)
|
2015-05-01 |
2018-03-07 |
Genentech, Inc. |
Masked anti-cd3 antibodies and methods of use
|
WO2016183104A1
(en)
|
2015-05-11 |
2016-11-17 |
Genentech, Inc. |
Compositions and methods of treating lupus nephritis
|
CA2983282A1
(en)
|
2015-05-12 |
2016-11-17 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
EP3095465A1
(en)
|
2015-05-19 |
2016-11-23 |
U3 Pharma GmbH |
Combination of fgfr4-inhibitor and bile acid sequestrant
|
ES2789500T5
(es)
|
2015-05-29 |
2023-09-20 |
Hoffmann La Roche |
Procedimientos terapéuticos y de diagnóstico para el cáncer
|
EP3302563A1
(en)
|
2015-05-29 |
2018-04-11 |
H. Hoffnabb-La Roche Ag |
Humanized anti-ebola virus glycoprotein antibodies and methods of use
|
KR102661078B1
(ko)
|
2015-05-29 |
2024-05-23 |
애브비 인코포레이티드 |
항-cd40 항체 및 그의 용도
|
CA2985818A1
(en)
|
2015-05-31 |
2016-12-08 |
Curegenix Corporation |
Combination compositions comprising an antagonist of porcupine and a pd-l/pd-1 axis antagonist for immunotherapy
|
WO2016196679A1
(en)
|
2015-06-02 |
2016-12-08 |
Genentech, Inc. |
Compositions and methods for using anti-il-34 antibodies to treat neurological diseases
|
SG10201911349YA
(en)
|
2015-06-05 |
2020-01-30 |
Genentech Inc |
Anti-tau antibodies and methods of use
|
MX2017015937A
(es)
|
2015-06-08 |
2018-12-11 |
Genentech Inc |
Métodos de tratamiento del cáncer con anticuerpos anti-ox40 y antagonistas de unión al eje de pd-1.
|
WO2016200836A1
(en)
|
2015-06-08 |
2016-12-15 |
Genentech, Inc. |
Methods of treating cancer using anti-ox40 antibodies
|
US11174313B2
(en)
|
2015-06-12 |
2021-11-16 |
Alector Llc |
Anti-CD33 antibodies and methods of use thereof
|
KR20180033502A
(ko)
|
2015-06-12 |
2018-04-03 |
알렉터 엘엘씨 |
항-cd33 항체 및 그의 사용 방법
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
AR104987A1
(es)
|
2015-06-15 |
2017-08-30 |
Genentech Inc |
Inmunoconjugados anticuerpo-fármaco unidos por enlazadores no peptídicos
|
EP3310378B1
(en)
|
2015-06-16 |
2024-01-24 |
F. Hoffmann-La Roche AG |
Anti-cll-1 antibodies and methods of use
|
FI3310814T3
(fi)
|
2015-06-16 |
2023-09-21 |
Hoffmann La Roche |
HUMANISOITUJA JA AFFINITEETTIKYPSIÄ FcRH5-VASTA-AINEITA JA KÄYTTÖMENETELMIÄ
|
EP3916018A1
(en)
|
2015-06-16 |
2021-12-01 |
Genentech, Inc. |
Anti-cd3 antibodies and methods of use
|
JP2018524312A
(ja)
|
2015-06-17 |
2018-08-30 |
ジェネンテック, インコーポレイテッド |
抗her2抗体及び使用方法
|
WO2016205320A1
(en)
|
2015-06-17 |
2016-12-22 |
Genentech, Inc. |
Methods of treating locally advanced or metastatic breast cancers using pd-1 axis binding antagonists and taxanes
|
CA2987797A1
(en)
|
2015-06-17 |
2016-12-22 |
Christopher Robert Bebbington |
Methods and compositions for treating fibrotic diseases
|
CN107810196B
(zh)
|
2015-06-24 |
2021-11-05 |
豪夫迈·罗氏有限公司 |
人源化的抗-Tau(pS422)抗体和使用方法
|
US9861621B2
(en)
|
2015-06-29 |
2018-01-09 |
Biomed Valley Discoveries, Inc. |
LPT-723 and immune checkpoint inhibitor combinations and methods of treatment
|
ES2898065T3
(es)
|
2015-06-29 |
2022-03-03 |
Ventana Med Syst Inc |
Materiales y procedimientos para realizar ensayos histoquímicos para proepirregulina y anfirregulina humanas
|
CA2989936A1
(en)
|
2015-06-29 |
2017-01-05 |
Genentech, Inc. |
Type ii anti-cd20 antibody for use in organ transplantation
|
JP6879947B2
(ja)
|
2015-06-30 |
2021-06-02 |
シージェン インコーポレイテッド |
抗ntb−a抗体及び関連組成物ならびに方法
|
WO2017023866A1
(en)
|
2015-07-31 |
2017-02-09 |
Boston Biomedical, Inc. |
Method of targeting stat3 and other non-druggable proteins
|
TWI797060B
(zh)
|
2015-08-04 |
2023-04-01 |
美商再生元醫藥公司 |
補充牛磺酸之細胞培養基及用法
|
US9884900B2
(en)
|
2015-08-04 |
2018-02-06 |
Acceleron Pharma Inc. |
Methods for treating Janus kinase-associated disorders by administering soluble transforming growth factor beta type II receptor
|
RU2765242C2
(ru)
|
2015-08-07 |
2022-01-27 |
Имаджинаб, Инк. |
Антигенсвязывающие конструкции против молекул-мишеней
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
EP3341415B1
(en)
|
2015-08-28 |
2021-03-24 |
H. Hoffnabb-La Roche Ag |
Anti-hypusine antibodies and uses thereof
|
WO2017046335A1
(en)
|
2015-09-18 |
2017-03-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
T cell receptors (tcr) and uses thereof for the diagnosis and treatment of diabetes
|
KR101920175B1
(ko)
|
2015-09-18 |
2018-11-19 |
추가이 세이야쿠 가부시키가이샤 |
Il-8에 결합하는 항체 및 그의 사용
|
EP3353206A1
(en)
|
2015-09-22 |
2018-08-01 |
Spring Bioscience Corporation |
Anti-ox40 antibodies and diagnostic uses thereof
|
TWI748962B
(zh)
|
2015-09-23 |
2021-12-11 |
美商建南德克公司 |
抗vegf抗體之最佳化變異體
|
JP6955487B2
(ja)
|
2015-09-24 |
2021-10-27 |
アブビトロ, エルエルシー |
Hiv抗体組成物および使用方法
|
KR20230125094A
(ko)
|
2015-09-25 |
2023-08-28 |
제넨테크, 인크. |
항-tigit 항체 및 이의 이용 방법
|
US10947598B2
(en)
|
2015-09-29 |
2021-03-16 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods for determining the metabolic status of lymphomas
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
AU2016329120B2
(en)
|
2015-10-02 |
2023-04-13 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies specific for a costimulatory TNF receptor
|
US20180282410A1
(en)
|
2015-10-02 |
2018-10-04 |
Hoffmann-La Roche Inc. |
Anti-cd3xrob04 bispecific t cell activating antigen binding molecules
|
CN108026177B
(zh)
|
2015-10-02 |
2021-11-26 |
豪夫迈·罗氏有限公司 |
双特异性抗cd19xcd3 t细胞活化性抗原结合分子
|
JP2018533930A
(ja)
|
2015-10-02 |
2018-11-22 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性t細胞活性化抗原結合分子
|
WO2017055391A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Bispecific t cell activating antigen binding molecules binding mesothelin and cd3
|
WO2017055385A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xgd2 bispecific t cell activating antigen binding molecules
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
WO2017055393A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xtim-3 bispecific t cell activating antigen binding molecules
|
CR20180161A
(es)
|
2015-10-02 |
2018-05-25 |
Hoffmann La Roche |
Anticuerpos biespecíficos para pd1 y tim3
|
WO2017055389A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Bispecific anti-ceaxcd3 t cell activating antigen binding molecules
|
WO2017055392A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xcd44v6 bispecific t cell activating antigen binding molecules
|
CN108368173B
(zh)
|
2015-10-02 |
2021-05-25 |
豪夫迈·罗氏有限公司 |
抗pd1抗体及使用方法
|
EP3359568B1
(en)
|
2015-10-07 |
2022-03-09 |
F. Hoffmann-La Roche AG |
Bispecific antibodies with tetravalency for a costimulatory tnf receptor
|
EP3362088B1
(en)
|
2015-10-12 |
2020-11-25 |
Institut National de la Sante et de la Recherche Medicale (INSERM) |
An agent capable of depleting cd8 t cells for the treatment of myocardial infarction or acute myocardial infarction
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
MA45326A
(fr)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation
|
US10604577B2
(en)
|
2015-10-22 |
2020-03-31 |
Allakos Inc. |
Methods and compositions for treating systemic mastocytosis
|
JP6949016B2
(ja)
|
2015-10-29 |
2021-10-13 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
抗バリアントFc領域抗体および使用法
|
EP3184547A1
(en)
|
2015-10-29 |
2017-06-28 |
F. Hoffmann-La Roche AG |
Anti-tpbg antibodies and methods of use
|
EP3368074A2
(en)
|
2015-10-30 |
2018-09-05 |
Hoffmann-La Roche AG |
Anti-factor d antibodies and conjugates
|
BR112018007703A2
(pt)
|
2015-10-30 |
2018-11-06 |
Genentech Inc |
anticorpos, ácido nucleico isolado, métodos de produção de um anticorpo e de tratamento de um distúrbio, composição farmacêutica, terapia de combinação e uso do anticorpo
|
EP3371217A1
(en)
|
2015-11-08 |
2018-09-12 |
H. Hoffnabb-La Roche Ag |
Methods of screening for multispecific antibodies
|
US20180327499A1
(en)
|
2015-11-13 |
2018-11-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti- nkg2d single domain antibodies and uses thereof
|
KR20180083402A
(ko)
|
2015-11-20 |
2018-07-20 |
오스트레일리언 바이오메디컬 컴퍼니 피티와이 리미티드 |
의학적 용도의 화합물
|
CN108697793B
(zh)
|
2015-11-23 |
2023-08-01 |
阿塞勒隆制药公司 |
治疗眼睛疾病的方法
|
US11248055B2
(en)
|
2015-11-27 |
2022-02-15 |
Ablynx N.V. |
Polypeptides inhibiting CD40L
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
CN108290954B
(zh)
|
2015-12-09 |
2022-07-26 |
豪夫迈·罗氏有限公司 |
Ii型抗cd20抗体用于降低抗药物抗体形成
|
IL259754B
(en)
|
2015-12-18 |
2022-09-01 |
Eisai R&D Man Co Ltd |
Immunoglobulins conjugated to lysine 447 (447k)
|
JP6088703B1
(ja)
|
2015-12-18 |
2017-03-01 |
中外製薬株式会社 |
抗c5抗体および使用方法
|
US10525137B2
(en)
|
2015-12-30 |
2020-01-07 |
Genentech, Inc. |
Formulations with reduced degradation of polysorbate
|
SG11201804951SA
(en)
|
2015-12-30 |
2018-07-30 |
Genentech Inc |
Use of tryptophan derivatives for protein formulations
|
WO2017118634A1
(en)
|
2016-01-04 |
2017-07-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of pd-1 and tim-3 as a measure for cd8+ cells in predicting and treating renal cell carcinoma
|
CN107531795B
(zh)
|
2016-01-05 |
2021-01-19 |
江苏恒瑞医药股份有限公司 |
Pcsk9抗体、其抗原结合片段及其医药用途
|
JP6949030B2
(ja)
|
2016-01-08 |
2021-10-13 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
Pd−1軸結合アンタゴニスト及び抗cea/抗cd3二重特異性抗体を用いたcea陽性がんの治療方法
|
WO2017127764A1
(en)
|
2016-01-20 |
2017-07-27 |
Genentech, Inc. |
High dose treatments for alzheimer's disease
|
WO2017129558A1
(en)
|
2016-01-25 |
2017-08-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting or treating myelopoiesis-driven cardiometabolic diseases and sepsis
|
WO2017129763A1
(en)
|
2016-01-28 |
2017-08-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of signet ring cell gastric cancer
|
ES2924741T3
(es)
|
2016-01-28 |
2022-10-10 |
Inst Nat Sante Rech Med |
Métodos para incrementar la potencia de los inhibidores del punto de control inmunitario
|
JP6970099B2
(ja)
|
2016-01-28 |
2021-11-24 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
ガンの処置のための方法及び医薬組成物
|
AU2017213826A1
(en)
|
2016-02-04 |
2018-08-23 |
Curis, Inc. |
Mutant smoothened and methods of using the same
|
KR20180119632A
(ko)
|
2016-02-29 |
2018-11-02 |
제넨테크, 인크. |
암에 대한 치료 및 진단 방법
|
RU2754369C2
(ru)
|
2016-03-02 |
2021-09-01 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Конъюгаты антитело-лекарственное средство на основе эрибулина и способы применения
|
CN116196412A
(zh)
|
2016-03-15 |
2023-06-02 |
中外制药株式会社 |
使用pd-1轴结合拮抗剂和抗gpc3抗体治疗癌症的方法
|
WO2017160954A1
(en)
|
2016-03-15 |
2017-09-21 |
Seattle Genetics, Inc. |
Combinations of pbd-based antibody drug conjugates with bcl-2 inhibitors
|
JP7015244B2
(ja)
|
2016-03-22 |
2022-02-02 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
プロテアーゼ活性化t細胞二重特異性分子
|
SG11201808085WA
(en)
|
2016-03-22 |
2018-10-30 |
Hoffmann La Roche |
Protease-activated t cell bispecific molecules
|
JP6943872B2
(ja)
|
2016-03-25 |
2021-10-06 |
ジェネンテック, インコーポレイテッド |
多重全抗体及び抗体複合体化薬物定量化アッセイ
|
EP3231813A1
(en)
|
2016-03-29 |
2017-10-18 |
F. Hoffmann-La Roche AG |
Trimeric costimulatory tnf family ligand-containing antigen binding molecules
|
KR20180128471A
(ko)
|
2016-03-29 |
2018-12-03 |
얀센 바이오테크 인코포레이티드 |
항-il12 및/또는 항-il23 항체의 증가된 투여 간격을 사용한 건선의 치료
|
US20200330459A1
(en)
|
2016-04-06 |
2020-10-22 |
Inserm (Institut National De La Santé Et La Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of age-related cardiometabolic diseases
|
US20170319688A1
(en)
|
2016-04-14 |
2017-11-09 |
Genentech, Inc. |
Anti-rspo3 antibodies and methods of use
|
EP3443120A2
(en)
|
2016-04-15 |
2019-02-20 |
H. Hoffnabb-La Roche Ag |
Methods for monitoring and treating cancer
|
MX2018012492A
(es)
|
2016-04-15 |
2019-06-06 |
Genentech Inc |
Métodos para monitorear y tratar el cáncer.
|
EP3445779A1
(en)
|
2016-04-22 |
2019-02-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of inflammatory skin diseases associated with desmoglein-1 deficiency
|
EP4276108A3
(en)
|
2016-04-27 |
2024-01-24 |
AbbVie Inc. |
Methods of treatment of diseases in which il-13 activity is detrimental using anti-il-13 antibodies
|
EP3452505A1
(en)
|
2016-05-02 |
2019-03-13 |
Ablynx NV |
Treatment of rsv infection
|
JP6675017B2
(ja)
|
2016-05-02 |
2020-04-01 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
コントースボディ−単鎖標的結合物質
|
US11098124B2
(en)
|
2016-05-03 |
2021-08-24 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
CD31 shed as a molecular target for imaging of inflammation
|
EP3452092B1
(en)
|
2016-05-06 |
2020-08-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Pharmaceutical compositions for the treatment of chemoresistant acute myeloid leukemia (aml)
|
WO2017194554A1
(en)
|
2016-05-10 |
2017-11-16 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Combinations therapies for the treatment of cancer
|
EP3243836A1
(en)
|
2016-05-11 |
2017-11-15 |
F. Hoffmann-La Roche AG |
C-terminally fused tnf family ligand trimer-containing antigen binding molecules
|
JP7285076B2
(ja)
|
2016-05-11 |
2023-06-01 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Tnfファミリーリガンドトリマーとテネイシン結合部分とを含む抗原結合分子
|
EP3455252B1
(en)
|
2016-05-11 |
2022-02-23 |
F. Hoffmann-La Roche AG |
Modified anti-tenascin antibodies and methods of use
|
EP3243832A1
(en)
|
2016-05-13 |
2017-11-15 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and pd1 binding moiety
|
ES2930255T3
(es)
|
2016-05-13 |
2022-12-09 |
Bioatla Inc |
Anticuerpos anti-Ror2, fragmentos de anticuerpos, sus inmunoconjugados y usos de los mismos
|
KR102419412B1
(ko)
|
2016-05-18 |
2022-07-12 |
베링거 인겔하임 인터내셔날 게엠베하 |
암 치료용 항-pd1 및 항-lag3 항체
|
ES2858151T3
(es)
|
2016-05-20 |
2021-09-29 |
Hoffmann La Roche |
Conjugados de PROTAC-anticuerpo y procedimientos de uso
|
EP3463452A1
(en)
|
2016-05-24 |
2019-04-10 |
Institut National de la Sante et de la Recherche Medicale (INSERM) |
Methods and pharmaceutical compositions for the treatment of non small cell lung cancer (nsclc) that coexists with chronic obstructive pulmonary disease (copd)
|
WO2017205741A1
(en)
|
2016-05-27 |
2017-11-30 |
Genentech, Inc. |
Bioanalytical method for the characterization of site-specific antibody-drug conjugates
|
WO2017202890A1
(en)
|
2016-05-27 |
2017-11-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating myeloma
|
WO2018220099A1
(en)
|
2017-06-02 |
2018-12-06 |
F. Hoffmann-La Roche Ag |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
US10639378B2
(en)
|
2016-06-06 |
2020-05-05 |
Genentech, Inc. |
Silvestrol antibody-drug conjugates and methods of use
|
MX2018015280A
(es)
|
2016-06-08 |
2019-08-12 |
Abbvie Inc |
Conjugados de anticuerpo y farmaco anti-egfr.
|
US20200121803A1
(en)
|
2016-06-08 |
2020-04-23 |
Abbvie Inc. |
Anti-cd98 antibodies and antibody drug conjugates
|
AU2017277916A1
(en)
|
2016-06-08 |
2019-01-03 |
Abbvie Inc. |
Anti-CD98 antibodies and antibody drug conjugates
|
US10640563B2
(en)
|
2016-06-08 |
2020-05-05 |
Abbvie Inc. |
Anti-B7-H3 antibodies and antibody drug conjugates
|
CA3027044A1
(en)
|
2016-06-08 |
2017-12-14 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
US20200338209A1
(en)
|
2016-06-08 |
2020-10-29 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
CA3027033A1
(en)
|
2016-06-08 |
2017-12-14 |
Abbvie Inc. |
Anti-cd98 antibodies and antibody drug conjugates
|
SG11201810970WA
(en)
|
2016-06-08 |
2019-01-30 |
Abbvie Inc |
Anti-egfr antibody drug conjugates
|
AU2017277422A1
(en)
|
2016-06-08 |
2019-01-03 |
Abbvie Inc. |
Anti-EGFR antibody drug conjugates
|
UA126799C2
(uk)
|
2016-06-10 |
2023-02-08 |
ЕЙСАЙ Ар ЕНД Ді МЕНЕДЖМЕНТ КО., ЛТД. |
Кон'югований імуноглобулін
|
GB201610198D0
(en)
|
2016-06-10 |
2016-07-27 |
Ucb Biopharma Sprl |
Anti-ige antibodies
|
WO2017223405A1
(en)
|
2016-06-24 |
2017-12-28 |
Genentech, Inc. |
Anti-polyubiquitin multispecific antibodies
|
WO2018007442A1
(en)
|
2016-07-06 |
2018-01-11 |
Ablynx N.V. |
Treatment of il-6r related diseases
|
CN109789092A
(zh)
|
2016-07-13 |
2019-05-21 |
哈佛学院院长等 |
抗原呈递细胞模拟支架及其制备和使用方法
|
DK3496739T3
(da)
|
2016-07-15 |
2021-05-10 |
Acceleron Pharma Inc |
Sammensætninger omfattende actriia-polypeptider til brug i behandlingen af pulmonal hypertension
|
US11618784B2
(en)
|
2016-07-19 |
2023-04-04 |
Teva Pharmaceuticals Australia Pty Ltd. |
Anti-CD47 combination therapy
|
WO2018014260A1
(en)
|
2016-07-20 |
2018-01-25 |
Nanjing Legend Biotech Co., Ltd. |
Multispecific antigen binding proteins and methods of use thereof
|
LT3490582T
(lt)
|
2016-07-27 |
2024-07-25 |
Acceleron Pharma Inc. |
Kompozicijos, skirtos naudoti gydant mielofibrozę
|
KR102591955B1
(ko)
|
2016-07-29 |
2023-10-19 |
추가이 세이야쿠 가부시키가이샤 |
증강된 fviii 보인자 기능 대체 활성을 갖는 이중특이성 항체
|
EP3491022A1
(en)
|
2016-07-29 |
2019-06-05 |
Institut National de la Sante et de la Recherche Medicale (INSERM) |
Antibodies targeting tumor associated macrophages and uses thereof
|
WO2018027204A1
(en)
|
2016-08-05 |
2018-02-08 |
Genentech, Inc. |
Multivalent and multiepitopic anitibodies having agonistic activity and methods of use
|
IL264626B
(en)
|
2016-08-05 |
2022-07-01 |
Chugai Pharmaceutical Co Ltd |
A preparation for the prevention or treatment of diseases related to il-8
|
WO2018029182A1
(en)
|
2016-08-08 |
2018-02-15 |
Ablynx N.V. |
Il-6r single variable domain antibodies for treatment of il-6r related diseases
|
EP3497129A1
(en)
|
2016-08-08 |
2019-06-19 |
H. Hoffnabb-La Roche Ag |
Therapeutic and diagnostic methods for cancer
|
EP3496763A1
(en)
|
2016-08-11 |
2019-06-19 |
Genentech, Inc. |
Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof
|
WO2018041989A1
(en)
|
2016-09-02 |
2018-03-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosing and treating refractory celiac disease type 2
|
JP2019533139A
(ja)
|
2016-09-08 |
2019-11-14 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
ネフローゼ症候群を診断及び処置するための方法
|
WO2018050833A1
(en)
|
2016-09-15 |
2018-03-22 |
Ablynx Nv |
Immunoglobulin single variable domains directed against macrophage migration inhibitory factor
|
SG10201607778XA
(en)
|
2016-09-16 |
2018-04-27 |
Chugai Pharmaceutical Co Ltd |
Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
|
JOP20190009A1
(ar)
|
2016-09-21 |
2019-01-27 |
Alx Oncology Inc |
أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
|
AU2017330405B2
(en)
|
2016-09-23 |
2024-02-01 |
Genentech, Inc. |
Uses of IL-13 antagonists for treating atopic dermatitis
|
EP3515948A4
(en)
|
2016-09-23 |
2020-04-08 |
CSL Limited |
COAGULATION FACTOR BINDING PROTEINS AND USES THEREOF
|
PL3519437T3
(pl)
|
2016-09-30 |
2022-01-17 |
F. Hoffmann-La Roche Ag |
Przeciwciała dwuswoiste przeciwko p95HER2
|
KR20190059305A
(ko)
|
2016-09-30 |
2019-05-30 |
얀센 바이오테크 인코포레이티드 |
항-il23 특이적 항체로 건선을 치료하는 안전하고 효과적인 방법
|
CN110198743B
(zh)
|
2016-10-05 |
2023-07-18 |
艾科赛扬制药股份有限公司 |
用于治疗肾脏疾病的组合物和方法
|
WO2018065501A1
(en)
|
2016-10-05 |
2018-04-12 |
F. Hoffmann-La Roche Ag |
Methods for preparing antibody drug conjugates
|
US10934532B2
(en)
|
2016-10-05 |
2021-03-02 |
Acceleron Pharma Inc. |
ALK4.ActRIIB heteromultimers
|
TWI775781B
(zh)
|
2016-10-06 |
2022-09-01 |
美商建南德克公司 |
癌症之治療性及診斷性方法
|
WO2018068201A1
(en)
|
2016-10-11 |
2018-04-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against ctla-4
|
US11149082B2
(en)
|
2016-10-17 |
2021-10-19 |
University Of Maryland, College Park |
Multispecific antibodies targeting human immunodeficiency virus and methods of using the same
|
US11078298B2
(en)
|
2016-10-28 |
2021-08-03 |
Banyan Biomarkers, Inc. |
Antibodies to ubiquitin C-terminal hydrolase L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) and related methods
|
JP2019535250A
(ja)
|
2016-10-29 |
2019-12-12 |
ジェネンテック, インコーポレイテッド |
抗mic抗体及び使用方法
|
US20190345500A1
(en)
|
2016-11-14 |
2019-11-14 |
|Nserm (Institut National De La Santé Et De La Recherche Médicale) |
Methods and pharmaceutical compositions for modulating stem cells proliferation or differentiation
|
CN109923128A
(zh)
|
2016-11-15 |
2019-06-21 |
基因泰克公司 |
用于用抗cd20/抗cd3双特异性抗体进行治疗的给药
|
US11840569B2
(en)
|
2016-11-16 |
2023-12-12 |
Ablynx N.V. |
T cell recruiting polypeptides capable of binding CD123 and TCR alpha/beta
|
MX2019005661A
(es)
|
2016-11-16 |
2019-10-07 |
Janssen Biotech Inc |
Método para tratar la psoriasis con el anticuerpo específico anti-il23.
|
EP3541830A1
(en)
|
2016-11-17 |
2019-09-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for increasing endogenous protein level
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
JP7274417B2
(ja)
|
2016-11-23 |
2023-05-16 |
イミュノア・セラピューティクス・インコーポレイテッド |
4-1bb結合タンパク質及びその使用
|
TWI797097B
(zh)
|
2016-11-28 |
2023-04-01 |
日商中外製藥股份有限公司 |
包含抗原結合域與運送部分的多胜肽
|
WO2018099968A1
(en)
|
2016-11-29 |
2018-06-07 |
Ablynx N.V. |
Treatment of infection by respiratory syncytial virus (rsv)
|
WO2018100190A1
(en)
|
2016-12-02 |
2018-06-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for diagnosing renal cell carcinoma
|
KR102645073B1
(ko)
|
2016-12-07 |
2024-03-11 |
제넨테크, 인크. |
항-타우 항체 및 이의 이용 방법
|
MA48595A
(fr)
|
2016-12-07 |
2020-03-18 |
Ac Immune Sa |
Anticorps anti-tau et leurs méthodes d'utilisation
|
WO2018108759A1
(en)
|
2016-12-13 |
2018-06-21 |
F. Hoffmann-La Roche Ag |
Method to determine the presence of a target antigen in a tumor sample
|
AU2017375646A1
(en)
|
2016-12-16 |
2019-05-30 |
Merck Patent Gmbh |
Methods for the use of galectin 3 binding protein detected in the urine for monitoring the severity and progression of lupus nephritis
|
WO2018114754A1
(en)
|
2016-12-19 |
2018-06-28 |
F. Hoffmann-La Roche Ag |
Combination therapy with targeted 4-1bb (cd137) agonists
|
KR20190093588A
(ko)
|
2016-12-20 |
2019-08-09 |
에프. 호프만-라 로슈 아게 |
항-cd20/항-cd3 이중특이성 항체 및 4-1bb(cd137) 작용물질의 병용 요법
|
GB201621806D0
(en)
|
2016-12-21 |
2017-02-01 |
Philogen Spa |
Immunocytokines with progressive activation mechanism
|
EP3360898A1
(en)
|
2017-02-14 |
2018-08-15 |
Boehringer Ingelheim International GmbH |
Bispecific anti-tnf-related apoptosis-inducing ligand receptor 2 and anti-cadherin 17 binding molecules for the treatment of cancer
|
CN108261391B
(zh)
|
2016-12-30 |
2022-03-01 |
江苏太平洋美诺克生物药业有限公司 |
稳定的包含cd147单克隆抗体的药物制剂
|
CN108261544B
(zh)
|
2016-12-30 |
2023-05-05 |
江苏太平洋美诺克生物药业股份有限公司 |
稳定的包含cd147单克隆抗体的药物制剂
|
KR20190099527A
(ko)
|
2017-01-03 |
2019-08-27 |
에프. 호프만-라 로슈 아게 |
항-4-1bb 클론 20h4.9를 포함하는 이중특이성 항원 결합 분자
|
WO2018134389A1
(en)
|
2017-01-23 |
2018-07-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating infections
|
KR20240038146A
(ko)
|
2017-01-30 |
2024-03-22 |
얀센 바이오테크 인코포레이티드 |
활성 건선성 관절염의 치료를 위한 항-tnf 항체, 조성물, 및 방법
|
CN110234355B
(zh)
|
2017-02-01 |
2021-11-09 |
浙江时迈药业有限公司 |
单体人IgG1 Fc和双特异性抗体
|
MA47442A
(fr)
|
2017-02-07 |
2019-12-18 |
Janssen Biotech Inc |
Anticorps anti-tnf, compositions et méthodes pour le traitement de la spondylarthrite ankylosante active
|
WO2018147960A1
(en)
|
2017-02-08 |
2018-08-16 |
Imaginab, Inc. |
Extension sequences for diabodies
|
EP3579872A1
(en)
|
2017-02-10 |
2019-12-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of cancers associated with activation of the mapk pathway
|
KR102362006B1
(ko)
|
2017-02-10 |
2022-02-14 |
제넨테크, 인크. |
항-트립타제 항체, 이의 조성물, 및 그의 용도
|
EP3589725A1
(en)
|
2017-02-28 |
2020-01-08 |
Vib Vzw |
Means and methods for oral protein delivery
|
KR20190134631A
(ko)
|
2017-03-01 |
2019-12-04 |
제넨테크, 인크. |
암의 진단 및 치료 방법
|
EP3589654A1
(en)
|
2017-03-02 |
2020-01-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies having specificity to nectin-4 and uses thereof
|
CR20190481A
(es)
|
2017-03-22 |
2020-01-06 |
Genentech Inc |
Composiciones de anticuerpo optimizados para el tratamiento de trastornos oculares
|
KR20200007776A
(ko)
|
2017-03-22 |
2020-01-22 |
제넨테크, 인크. |
히드로겔 가교된 히알루론산 전구약물 조성물 및 방법
|
US20210186982A1
(en)
|
2017-03-24 |
2021-06-24 |
Universite Nice Sophia Antipolis |
Methods and compositions for treating melanoma
|
WO2018178030A1
(en)
|
2017-03-27 |
2018-10-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating degenerative muscular and/or neurological conditions or diseases
|
BR112019017629A2
(pt)
|
2017-03-27 |
2020-04-07 |
Hoffmann La Roche |
receptor de união ao antígeno, polinucleotídeo isolado, vetor, célula t transduzida, métodos para o tratamento de uma doença e para induzir a lise, utilização do receptor e receptor
|
CN110662560B
(zh)
|
2017-03-27 |
2024-06-28 |
豪夫迈·罗氏有限公司 |
改进的抗原结合受体
|
WO2018178029A1
(en)
|
2017-03-27 |
2018-10-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating degenerative muscular and/or neurological conditions or diseases
|
WO2018178078A1
(en)
|
2017-03-28 |
2018-10-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New tau species
|
SG11201908326YA
(en)
|
2017-03-28 |
2019-10-30 |
Genentech Inc |
Methods of treating neurodegenerative diseases
|
EP3601346A1
(en)
|
2017-03-29 |
2020-02-05 |
H. Hoffnabb-La Roche Ag |
Bispecific antigen binding molecule for a costimulatory tnf receptor
|
CN110573528B
(zh)
|
2017-03-29 |
2023-06-09 |
豪夫迈·罗氏有限公司 |
针对共刺激性tnf受体的双特异性抗原结合分子
|
WO2018178074A1
(en)
|
2017-03-29 |
2018-10-04 |
F. Hoffmann-La Roche Ag |
Trimeric antigen binding molecules specific for a costimulatory tnf receptor
|
WO2018178936A1
(en)
|
2017-03-30 |
2018-10-04 |
Duke University |
Radiolabeled biomolecules and their use
|
BR112019018767A2
(pt)
|
2017-04-03 |
2020-05-05 |
Hoffmann La Roche |
anticorpos, molécula de ligação ao antígeno biespecífica, um ou mais polinucleotídeos isolados, um ou mais vetores, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, usos, método para tratar uma doença em um indivíduo e invenção
|
WO2018184965A1
(en)
|
2017-04-03 |
2018-10-11 |
F. Hoffmann-La Roche Ag |
Immunoconjugates of il-2 with an anti-pd-1 and tim-3 bispecific antibody
|
BR112019017329A2
(pt)
|
2017-04-03 |
2020-04-14 |
Hoffmann La Roche |
imunoconjugados, um ou mais polinucleotídeos e vetores, métodos para a produção de um imunoconjugado, tratamento de uma doença e para a estimulação do sistema imunológico, composição, uso do imunoconjugado, invenção e usos da composição
|
RU2766234C2
(ru)
|
2017-04-04 |
2022-02-10 |
Ф. Хоффманн-Ля Рош Аг |
Новые биспецифические антигенсвязывающие молекулы, обладающие способностью специфически связываться с cd40 и fap
|
EP4112644A1
(en)
|
2017-04-05 |
2023-01-04 |
F. Hoffmann-La Roche AG |
Anti-lag3 antibodies
|
AU2018247794A1
(en)
|
2017-04-05 |
2019-08-22 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies specifically binding to PD1 and LAG3
|
CN108728444A
(zh)
|
2017-04-18 |
2018-11-02 |
长春华普生物技术股份有限公司 |
免疫调节性多核苷酸及其应用
|
EP3612648A1
(en)
|
2017-04-18 |
2020-02-26 |
Université Libre de Bruxelles |
Biomarkers and targets for proliferative diseases
|
US11932694B2
(en)
|
2017-04-19 |
2024-03-19 |
Bluefin Biomedicine, Inc. |
Anti-VTCN1 antibodies and antibody drug conjugates
|
PE20200150A1
(es)
|
2017-04-21 |
2020-01-17 |
Genentech Inc |
Uso de antagonistas de klk5 para el tratamiento de una enfermedad
|
US20220135670A1
(en)
|
2017-04-27 |
2022-05-05 |
Tesaro, Inc. |
Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof
|
KR20200016232A
(ko)
|
2017-05-05 |
2020-02-14 |
알라코스 인크. |
알레르기성 안구 질환을 치료하기 위한 방법 및 조성물
|
WO2018206734A1
(en)
|
2017-05-11 |
2018-11-15 |
Vib Vzw |
Glycosylation of variable immunoglobulin domains
|
EP3625251A1
(en)
|
2017-05-15 |
2020-03-25 |
University Of Rochester |
Broadly neutralizing anti-influenza monoclonal antibody and uses thereof
|
EP3403649A1
(en)
|
2017-05-16 |
2018-11-21 |
Bayer Pharma Aktiengesellschaft |
Inhibitors and antagonists of gpr84 for the treatment of endometriosis
|
CA3062981A1
(en)
|
2017-05-17 |
2018-11-22 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Flt3 inhibitors for improving pain treatments by opioids
|
CA3064443A1
(en)
*
|
2017-05-24 |
2018-11-29 |
Development Center For Biotechnology |
Humanized antibodies against globo h and uses thereof in cancer treatments
|
EP3406253A1
(en)
|
2017-05-24 |
2018-11-28 |
Bayer Aktiengesellschaft |
Inhibitors and antagonists of human pycr1
|
EP3409322A1
(en)
|
2017-06-01 |
2018-12-05 |
F. Hoffmann-La Roche AG |
Treatment method
|
CN110997001A
(zh)
|
2017-06-02 |
2020-04-10 |
默克专利股份有限公司 |
Mmp13结合免疫球蛋白
|
CA3064318A1
(en)
|
2017-06-02 |
2018-12-06 |
Merck Patent Gmbh |
Polypeptides binding adamts5, mmp13 and aggrecan
|
SG10202113337YA
(en)
|
2017-06-02 |
2021-12-30 |
Ablynx Nv |
Aggrecan binding immunoglobulins
|
AU2018277343A1
(en)
|
2017-06-02 |
2020-01-02 |
Ablynx N.V. |
Adamts binding immunoglobulins
|
EP3634582A1
(en)
|
2017-06-08 |
2020-04-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating hyperpigmentation disorders
|
JP7265487B2
(ja)
|
2017-06-08 |
2023-04-26 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
関心対象のアナライトを検出するための全細胞センサにおいて使用するためのキメラ受容体
|
CN111093701A
(zh)
*
|
2017-06-15 |
2020-05-01 |
财团法人生物技术开发中心 |
含有抗globo h抗体的抗体药物偶联物及其用途
|
US20210403573A1
(en)
|
2017-06-22 |
2021-12-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of fibrosis with agents capable of inhibiting the activation of mucosal-associated invariant t (mait) cells
|
WO2019000223A1
(en)
|
2017-06-27 |
2019-01-03 |
Nanjing Legend Biotech Co., Ltd. |
ENABLERS OF IMMUNE EFFECTOR CELLS OF CHIMERIC ANTIBODIES AND METHODS OF USE THEREOF
|
WO2019002548A1
(en)
|
2017-06-29 |
2019-01-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
TREATMENT OF MIGRAINE WITH TREK1, TREK2 AGONIZATION OR HETEROMERS COMPRISING SAME
|
MA49565A
(fr)
|
2017-07-11 |
2020-05-20 |
Compass Therapeutics Llc |
Anticorps agonistes qui lient cd137 humain et leurs utilisations
|
CN111108126B
(zh)
|
2017-07-19 |
2024-04-26 |
非营利性组织佛兰芒综合大学生物技术研究所 |
血清白蛋白结合剂
|
WO2019016310A1
(en)
|
2017-07-20 |
2019-01-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
METHODS AND COMPOSITIONS FOR TREATING CANCERS
|
WO2019018757A1
(en)
|
2017-07-21 |
2019-01-24 |
Genentech, Inc. |
THERAPEUTIC AND DIAGNOSTIC METHODS FOR CANCER
|
EP3658581A1
(en)
|
2017-07-24 |
2020-06-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies and peptides to treat hcmv related diseases
|
US11926664B2
(en)
|
2017-07-25 |
2024-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for modulating monocytopoiesis
|
KR20200036889A
(ko)
|
2017-07-28 |
2020-04-07 |
에프. 호프만-라 로슈 아게 |
이중특이성 항체 제형
|
MA47691A
(fr)
|
2017-08-03 |
2020-01-08 |
Alector Llc |
Anticorps anti-cd33 et leurs procédés d'utilisation
|
EP3444275A1
(en)
|
2017-08-16 |
2019-02-20 |
Exiris S.r.l. |
Monoclonal antibody anti-fgfr4
|
CN111511762A
(zh)
|
2017-08-21 |
2020-08-07 |
天演药业公司 |
抗cd137分子及其用途
|
US20200197547A1
(en)
|
2017-08-30 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-mesothelin radiolabelled single domain antibodies suitable for the imaging and treatment of cancers
|
EP3457139A1
(en)
|
2017-09-19 |
2019-03-20 |
Promise Advanced Proteomics |
Antibody-like peptides for quantifying therapeutic antibodies
|
US20200216542A1
(en)
|
2017-09-20 |
2020-07-09 |
Chugai Seiyaku Kabushiki Kaisha |
Dosage regimen for combination therapy using pd-1 axis binding antagonists and gpc3 targeting agent
|
WO2019057742A1
(en)
|
2017-09-20 |
2019-03-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR MODULATION OF AUTOPHAGIA
|
TW201922780A
(zh)
|
2017-09-25 |
2019-06-16 |
美商健生生物科技公司 |
以抗il12/il23抗體治療狼瘡之安全且有效之方法
|
BR112020007154A2
(pt)
|
2017-10-20 |
2020-09-29 |
F. Hoffmann-La Roche Ag |
método para produzir um polipeptídeo e polipeptídeos heterodimérico
|
WO2019081456A1
(en)
|
2017-10-24 |
2019-05-02 |
Bayer Aktiengesellschaft |
USE OF SGC ACTIVATORS AND STIMULATORS COMPRISING A BETA2 SUBUNIT
|
TWI832824B
(zh)
|
2017-10-30 |
2024-02-21 |
瑞士商赫孚孟拉羅股份公司 |
自單特異性抗體於活體內產生多特異性抗體之方法
|
JP2021502063A
(ja)
|
2017-10-31 |
2021-01-28 |
フエー・イー・ベー・フエー・ゼツト・ウエー |
新規抗原結合性キメラタンパク質とその方法及び使用
|
US11718679B2
(en)
|
2017-10-31 |
2023-08-08 |
Compass Therapeutics Llc |
CD137 antibodies and PD-1 antagonists and uses thereof
|
CN111315781A
(zh)
|
2017-11-01 |
2020-06-19 |
豪夫迈·罗氏有限公司 |
用靶向性ox40激动剂的组合疗法
|
WO2019086394A1
(en)
|
2017-11-01 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
The compbody - a multivalent target binder
|
SG11202002903XA
(en)
|
2017-11-01 |
2020-04-29 |
Hoffmann La Roche |
Bispecific 2+1 contorsbodies
|
WO2019086499A1
(en)
|
2017-11-01 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
Novel tnf family ligand trimer-containing antigen binding molecules
|
EP3707510B1
(en)
|
2017-11-06 |
2024-06-26 |
F. Hoffmann-La Roche AG |
Diagnostic and therapeutic methods for cancer
|
EP3706795A4
(en)
|
2017-11-09 |
2021-10-13 |
Pinteon Therapeutics Inc. |
METHODS AND COMPOSITIONS FOR GENERATING AND USING HUMANIZED CONFORMATION SPECIFIC PHOSPHORYLATED TAU ANTIBODIES
|
CN111386285A
(zh)
|
2017-11-15 |
2020-07-07 |
诺沃挪第克公司 |
增强fx活化的因子x结合物
|
US11851497B2
(en)
|
2017-11-20 |
2023-12-26 |
Compass Therapeutics Llc |
CD137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
WO2019101995A1
(en)
|
2017-11-27 |
2019-05-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for cardiac regeneration
|
WO2019107380A1
(ja)
|
2017-11-28 |
2019-06-06 |
中外製薬株式会社 |
抗原結合ドメインおよび運搬部分を含むポリペプチド
|
CA3081770A1
(en)
|
2017-11-29 |
2019-06-06 |
Csl Limited |
Method of treating or preventing ischemia-reperfusion injury
|
CN111757892A
(zh)
|
2017-12-01 |
2020-10-09 |
西雅图基因公司 |
用于治疗乳腺癌的人源化抗liv1抗体
|
CA3083946A1
(en)
|
2017-12-01 |
2019-06-06 |
Seattle Genetics, Inc. |
Cd47 antibodies and uses thereof for treating cancer
|
AU2018382966A1
(en)
|
2017-12-14 |
2020-04-09 |
F. Hoffmann-La Roche Ag |
Use of a CEA CD3 bispecific antibody and a PD-1 axis binding antagonist in a dosage regime to treat cancer
|
PE20201339A1
(es)
|
2017-12-19 |
2020-11-25 |
Univ Rockefeller |
Variantes de dominio de fc de igg humana con funcion efectora mejorada
|
CN111492243A
(zh)
|
2017-12-21 |
2020-08-04 |
豪夫迈·罗氏有限公司 |
用于新颖抗原结合模块的特异性测试的car-t细胞测定法
|
EP3502140A1
(en)
|
2017-12-21 |
2019-06-26 |
F. Hoffmann-La Roche AG |
Combination therapy of tumor targeted icos agonists with t-cell bispecific molecules
|
BR112020011469A2
(pt)
|
2017-12-21 |
2020-11-24 |
F. Hoffmann-La Roche Ag |
anticorpos, molécula de ligação ao antígeno biespecífica, um ou mais polinucleotídeos isolados, um ou mais vetores, célula hospedeira, método para produzir um anticorpo, composição farmacêutica, uso do anticorpo, método de tratamento de uma doença e invenção
|
CN111247429A
(zh)
|
2017-12-21 |
2020-06-05 |
豪夫迈·罗氏有限公司 |
用于新颖抗原结合模块的特异性测试的通用报告细胞测定法
|
WO2019126472A1
(en)
|
2017-12-22 |
2019-06-27 |
Genentech, Inc. |
Use of pilra binding agents for treatment of a disease
|
EP3732202A4
(en)
|
2017-12-28 |
2022-06-15 |
Nanjing Legend Biotech Co., Ltd. |
SINGLE DOMAIN ANTIBODIES AND VARIANTS THEREOF AGAINST TIGIT
|
EP3732193A1
(en)
|
2017-12-29 |
2020-11-04 |
Alector LLC |
Anti-tmem106b antibodies and methods of use thereof
|
EP3735590A1
(en)
|
2018-01-04 |
2020-11-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma resistant
|
CA3084518A1
(en)
|
2018-01-15 |
2019-07-18 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against pd-1
|
CA3088649A1
(en)
|
2018-01-16 |
2019-07-25 |
Lakepharma, Inc. |
Bispecific antibody that binds cd3 and another target
|
WO2019145413A1
(en)
|
2018-01-25 |
2019-08-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antagonists of il-33 for use in methods for preventing ischemia reperfusion injury in an organ
|
US11472874B2
(en)
|
2018-01-31 |
2022-10-18 |
Alector Llc |
Anti-MS4A4A antibodies and methods of use thereof
|
WO2019149716A1
(en)
|
2018-01-31 |
2019-08-08 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies comprising an antigen-binding site binding to lag3
|
EP3746470A1
(en)
|
2018-01-31 |
2020-12-09 |
F. Hoffmann-La Roche AG |
Stabilized immunoglobulin domains
|
WO2019148445A1
(en)
|
2018-02-02 |
2019-08-08 |
Adagene Inc. |
Precision/context-dependent activatable antibodies, and methods of making and using the same
|
WO2019148444A1
(en)
|
2018-02-02 |
2019-08-08 |
Adagene Inc. |
Anti-ctla4 antibodies and methods of making and using the same
|
WO2019150309A1
(en)
|
2018-02-02 |
2019-08-08 |
Hammack Scott |
Modulators of gpr68 and uses thereof for treating and preventing diseases
|
MX2020008294A
(es)
|
2018-02-06 |
2020-11-18 |
Ablynx Nv |
Metodos de tratamiento de episodio inicial de ttp con dominios variables simples de inmunoglobulina.
|
JP7475275B2
(ja)
|
2018-02-08 |
2024-04-26 |
ジェネンテック, インコーポレイテッド |
二重特異性抗原結合分子及びその使用方法
|
CR20200394A
(es)
|
2018-02-09 |
2020-11-05 |
Genentech Inc |
Métodos terapéuticos y diagnósticos para enfermedades inflrmatorias mediadas por mostocitos
|
TWI829667B
(zh)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合gprc5d之抗體
|
EP3752134A1
(en)
|
2018-02-16 |
2020-12-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating vitiligo
|
AU2019225249A1
(en)
|
2018-02-26 |
2020-09-17 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-PD-L1 antagonist antibodies
|
EP3759491A1
(en)
|
2018-03-01 |
2021-01-06 |
H. Hoffnabb-La Roche Ag |
Specificity assay for novel target antigen binding moieties
|
JP2021514649A
(ja)
|
2018-03-01 |
2021-06-17 |
ブレイエ・ユニバージテイト・ブリュッセルVrije Universiteit Brussel |
ヒトpd−l1結合免疫グロブリン
|
KR20200129125A
(ko)
|
2018-03-05 |
2020-11-17 |
얀센 바이오테크 인코포레이티드 |
항-il23 특이적 항체로 크론병을 치료하는 방법
|
EP3765489A1
(en)
|
2018-03-13 |
2021-01-20 |
F. Hoffmann-La Roche AG |
Therapeutic combination of 4-1 bb agonists with anti-cd20 antibodies
|
JP7098741B2
(ja)
|
2018-03-13 |
2022-07-11 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
標的化4-1bb(cd137)アゴニストとの併用療法
|
MX2020009514A
(es)
|
2018-03-14 |
2020-12-07 |
Beijing Xuanyi Pharmasciences Co Ltd |
Anticuerpos anti-claudina 18.2 (cldn18.2).
|
US20200040103A1
(en)
|
2018-03-14 |
2020-02-06 |
Genentech, Inc. |
Anti-klk5 antibodies and methods of use
|
JP7508368B2
(ja)
|
2018-03-15 |
2024-07-01 |
中外製薬株式会社 |
ジカウイルスに対して交差反応性を有する抗デングウイルス抗体および使用方法
|
EP3768720A4
(en)
|
2018-03-20 |
2022-01-05 |
Wuxi Biologics Ireland Limited |
NEW ANTI-LAG-3 ANTIBODY POLYPEPTIDE
|
EP3768314A4
(en)
|
2018-03-21 |
2022-01-05 |
ALX Oncology Inc. |
ANTIBODIES AGAINST ALPHA SIGNAL REGULATING PROTEIN AND METHODS OF USE
|
CA3088676A1
(en)
|
2018-03-23 |
2019-09-26 |
Universite Libre De Bruxelles |
Wnt signaling agonist molecules
|
CN111936625A
(zh)
|
2018-03-29 |
2020-11-13 |
豪夫迈·罗氏有限公司 |
调节哺乳动物细胞中的生乳活性
|
KR20200138720A
(ko)
|
2018-03-30 |
2020-12-10 |
난징 레전드 바이오테크 씨오., 엘티디. |
Lag-3에 대한 단일-도메인 항체 및 이의 용도
|
US11840568B2
(en)
|
2018-04-02 |
2023-12-12 |
Mab-Venture Biopharm Co., Ltd. |
Lymphocyte activation gene-3 (LAG-3) binding antibody and use thereof
|
EP3775902B1
(en)
|
2018-04-04 |
2023-02-22 |
F. Hoffmann-La Roche AG |
Diagnostic assays to detect tumor antigens in cancer patients
|
WO2019193375A1
(en)
|
2018-04-04 |
2019-10-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of fzd7 inhibitors for the treatment of retinal neovascularization
|
TW202011029A
(zh)
|
2018-04-04 |
2020-03-16 |
美商建南德克公司 |
偵測及定量fgf21之方法
|
WO2019192972A1
(en)
|
2018-04-04 |
2019-10-10 |
F. Hoffmann-La Roche Ag |
Diagnostic assays to detect tumor antigens in cancer patients
|
EP3552631A1
(en)
|
2018-04-10 |
2019-10-16 |
Inatherys |
Antibody-drug conjugates and their uses for the treatment of cancer
|
EP3774900A1
(en)
|
2018-04-13 |
2021-02-17 |
F. Hoffmann-La Roche AG |
Her2-targeting antigen binding molecules comprising 4-1bbl
|
AR114789A1
(es)
|
2018-04-18 |
2020-10-14 |
Hoffmann La Roche |
Anticuerpos anti-hla-g y uso de los mismos
|
AR115052A1
(es)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
Anticuerpos multiespecíficos y utilización de los mismos
|
WO2019207030A1
(en)
|
2018-04-26 |
2019-10-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting a response with an immune checkpoint inhibitor in a patient suffering from a lung cancer
|
US11958895B2
(en)
|
2018-05-03 |
2024-04-16 |
University Of Rochester |
Anti-influenza neuraminidase monoclonal antibodies and uses thereof
|
CA3100005A1
(en)
|
2018-05-14 |
2019-11-21 |
Werewolf Therapeutics, Inc. |
Activatable cytokine polypeptides and methods of use thereof
|
WO2019222295A1
(en)
|
2018-05-14 |
2019-11-21 |
Werewolf Therapeutics, Inc. |
Activatable interleukin-2 polypeptides and methods of use thereof
|
KR102470059B1
(ko)
|
2018-05-18 |
2022-11-22 |
에프. 호프만-라 로슈 아게 |
큰 핵산의 표적화된 세포내 전달
|
EP3569618A1
(en)
|
2018-05-19 |
2019-11-20 |
Boehringer Ingelheim International GmbH |
Antagonizing cd73 antibody
|
MA52753A
(fr)
|
2018-05-25 |
2021-04-21 |
Alector Llc |
Anticorps anti-sirpa et leurs procédés d'utilisation
|
WO2019230868A1
(ja)
|
2018-05-30 |
2019-12-05 |
中外製薬株式会社 |
単ドメイン抗体含有リガンド結合分子
|
BR112020024549A2
(pt)
|
2018-06-01 |
2021-03-02 |
Eisai R&D Management Co., Ltd. |
conjugados anticorpo-fármaco de modulador de splicing e métodos de uso
|
MX2020012940A
(es)
|
2018-06-01 |
2021-03-25 |
Eisai R&D Man Co Ltd |
Metodos de uso de moduladores de empalme.
|
JP7372237B2
(ja)
|
2018-06-04 |
2023-10-31 |
中外製薬株式会社 |
細胞質内での半減期が変化した抗原結合分子
|
US20210230300A1
(en)
|
2018-06-04 |
2021-07-29 |
Bayer Aktiengesellschaft |
Inhibitors of shp2
|
EP3802598A1
(en)
|
2018-06-09 |
2021-04-14 |
Boehringer Ingelheim International GmbH |
Dll3-cd3 bispecific antibodies
|
WO2019241730A2
(en)
|
2018-06-15 |
2019-12-19 |
Flagship Pioneering Innovations V, Inc. |
Increasing immune activity through modulation of postcellular signaling factors
|
TW202016144A
(zh)
|
2018-06-21 |
2020-05-01 |
日商第一三共股份有限公司 |
包括cd3抗原結合片段之組成物及其用途
|
SG11202012446UA
(en)
|
2018-06-23 |
2021-01-28 |
Genentech Inc |
Methods of treating lung cancer with a pd-1 axis binding antagonist, a platinum agent, and a topoisomerase ii inhibitor
|
EP3814377A2
(en)
|
2018-06-29 |
2021-05-05 |
Alector LLC |
Anti-sirp-beta1 antibodies and methods of use thereof
|
US11845797B2
(en)
|
2018-07-03 |
2023-12-19 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
JP2021528988A
(ja)
|
2018-07-04 |
2021-10-28 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
新規の二重特異性アゴニスト4−1bb抗原結合分子
|
WO2020008083A1
(es)
|
2018-07-05 |
2020-01-09 |
Consejo Superior De Investigaciones Científicas |
Diana terapéutica en receptores de quimiocinas para la selección de compuestos útiles para el tratamiento de procesos patológicos que implican la señalización de quimiocinas
|
HUE061841T2
(hu)
|
2018-07-13 |
2023-08-28 |
Alector Llc |
Anti-sortilin antitestek és felhasználásuk módszerei
|
US20200025776A1
(en)
|
2018-07-18 |
2020-01-23 |
Janssen Biotech, Inc. |
Sustained Response Predictors After Treatment With Anti-IL23 Specific Antibody
|
MX2021000558A
(es)
|
2018-07-18 |
2021-04-13 |
Genentech Inc |
Metodos para tratar el cancer de pulmon con un antagonista de fijacion al eje pd-1, un antimetabolito y un agente de platino.
|
CA3106114A1
(en)
|
2018-07-20 |
2020-01-23 |
Surface Oncology, Inc. |
Anti-cd112r compositions and methods
|
IL280563B1
(en)
|
2018-08-01 |
2024-06-01 |
Imcheck Therapeutics Sas |
Antibodies against BTN3A and their uses for the treatment of cancer and infectious diseases
|
BR112021001693A2
(pt)
|
2018-08-03 |
2021-05-04 |
Chugai Seiyaku Kabushiki Kaisha |
molécula de ligação ao antígeno contendo dois domínios de ligação ao antígeno q ligados entre si
|
AR115925A1
(es)
|
2018-08-08 |
2021-03-10 |
Genentech Inc |
Uso de derivados de triptófano y l-metionina para formulación de proteínas
|
CN112839960A
(zh)
|
2018-08-10 |
2021-05-25 |
中外制药株式会社 |
抗cd137抗原结合分子及其应用
|
TW202021618A
(zh)
|
2018-08-17 |
2020-06-16 |
美商23與我有限公司 |
抗il1rap抗體及其使用方法
|
US11548938B2
(en)
|
2018-08-21 |
2023-01-10 |
Quidel Corporation |
DbpA antibodies and uses thereof
|
CN113801229A
(zh)
|
2018-08-31 |
2021-12-17 |
艾利妥 |
抗cd33抗体及其使用方法
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
WO2020049026A1
(en)
|
2018-09-05 |
2020-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating asthma and allergic diseases
|
GB2576914A
(en)
|
2018-09-06 |
2020-03-11 |
Kymab Ltd |
Antigen-binding molecules comprising unpaired variable domains produced in mammals
|
EP3849545A1
(en)
|
2018-09-10 |
2021-07-21 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods for the treatment of neurofibromatosis
|
US20220047701A1
(en)
|
2018-09-10 |
2022-02-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Combination of her2/neu antibody with heme for treating cancer
|
WO2020053147A1
(en)
|
2018-09-10 |
2020-03-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of an inhibitor of ntsr1 activation or expression for preventing weight loss, muscle loss, and protein blood level decrease in subjects in need thereof
|
US20220023265A1
(en)
|
2018-09-17 |
2022-01-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of inhibitors of phosphatase activity of soluble epoxide for the treatment of cardiometabolic diseases
|
AR114732A1
(es)
|
2018-09-18 |
2020-10-07 |
Hoffmann La Roche |
Utilización de un inhibidor de catepsina s contra la formación de anticuerpos antifármaco
|
MX2021003214A
(es)
|
2018-09-19 |
2021-05-12 |
Genentech Inc |
Metodos terapeuticos y de diagnostico para el cancer de vejiga.
|
CN113396160A
(zh)
|
2018-09-19 |
2021-09-14 |
国家医疗保健研究所 |
治疗对免疫检查点疗法具有抗性的癌症的方法和药物组合物
|
MX2021003213A
(es)
|
2018-09-21 |
2021-05-12 |
Genentech Inc |
Metodos de diagnostico para cancer de mama triple negativo.
|
BR112021005467A2
(pt)
|
2018-09-24 |
2021-06-22 |
Janssen Biotech, Inc. |
método seguro e eficaz para tratar colite ulcerativa com anticorpo anti-il12/il23
|
EP3856772A1
(en)
|
2018-09-25 |
2021-08-04 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of antagonists of th17 cytokines for the treatment of bronchial remodeling in patients suffering from allergic asthma
|
MX2021003543A
(es)
|
2018-09-27 |
2021-06-23 |
Xilio Dev Inc |
Polipeptidos de citocinas enmascaradas.
|
JP2022511396A
(ja)
|
2018-10-01 |
2022-01-31 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Cd40への三価結合を伴う二重特異性抗原結合分子
|
KR20210069675A
(ko)
|
2018-10-01 |
2021-06-11 |
에프. 호프만-라 로슈 아게 |
항-fap 클론 212를 포함하는 이중특이적 항원 결합 분자
|
WO2020070062A1
(en)
|
2018-10-01 |
2020-04-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of tim-3 inhibitors for the treatment of exacerbations in patients suffering from severe asthma
|
US20210340278A1
(en)
|
2018-10-04 |
2021-11-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of mucosal inflammatory diseases
|
WO2020070288A1
(en)
|
2018-10-05 |
2020-04-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and systems for controlling the agonistic properties of antibody variable domains by light
|
EP3636657A1
(en)
|
2018-10-08 |
2020-04-15 |
Ablynx N.V. |
Chromatography-free antibody purification method
|
US20200109200A1
(en)
|
2018-10-09 |
2020-04-09 |
Genentech, Inc. |
Methods and systems for determining synapse formation
|
US20210347898A1
(en)
|
2018-10-09 |
2021-11-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of alpha-v-integrin (cd51) inhibitors for the treatment of cardiac fibrosis
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
EP3867646A1
(en)
|
2018-10-18 |
2021-08-25 |
F. Hoffmann-La Roche AG |
Diagnostic and therapeutic methods for sarcomatoid kidney cancer
|
WO2020079162A1
(en)
|
2018-10-18 |
2020-04-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for inducing full ablation of hematopoiesis
|
TW202037381A
(zh)
|
2018-10-24 |
2020-10-16 |
瑞士商赫孚孟拉羅股份公司 |
綴合化學降解誘導劑及使用方法
|
CA3117051A1
(en)
|
2018-11-05 |
2020-05-14 |
Genentech, Inc. |
Methods of producing two chain proteins in prokaryotic host cells
|
GB201818477D0
(en)
|
2018-11-13 |
2018-12-26 |
Emstopa Ltd |
Tissue plasminogen activator antibodies and method of use thereof
|
US11046769B2
(en)
|
2018-11-13 |
2021-06-29 |
Compass Therapeutics Llc |
Multispecific binding constructs against checkpoint molecules and uses thereof
|
WO2020104479A1
(en)
|
2018-11-20 |
2020-05-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers and resistant cancers with anti transferrin receptor 1 antibodies
|
AU2019383017A1
(en)
|
2018-11-20 |
2021-06-03 |
Janssen Biotech, Inc. |
Safe and effective method of treating psoriasis with anti-IL-23 specific antibody
|
US20220332800A1
(en)
|
2018-11-20 |
2022-10-20 |
Takeda Vaccines, Inc. |
Novel anti-zika virus antibodies and uses thereof
|
AU2018451747A1
(en)
|
2018-12-06 |
2021-06-17 |
F. Hoffmann-La Roche Ag |
Combination therapy of diffuse large B-cell lymphoma comprising an anti-CD79b immunoconjugates, an alkylating agent and an anti-CD20 antibody
|
WO2020115261A1
(en)
|
2018-12-07 |
2020-06-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
WO2020123275A1
(en)
|
2018-12-10 |
2020-06-18 |
Genentech, Inc. |
Photocrosslinking peptides for site specific conjugation to fc-containing proteins
|
WO2020120592A1
(en)
|
2018-12-12 |
2020-06-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating melanoma
|
EP3894438A1
(en)
|
2018-12-13 |
2021-10-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New anti tau svqivykpv epitope single domain antibody
|
CN113271981A
(zh)
|
2018-12-13 |
2021-08-17 |
卫材R&D管理有限公司 |
荷伯希二烯抗体-药物缀合物及使用方法
|
EP3897722A4
(en)
|
2018-12-18 |
2022-09-14 |
Janssen Biotech, Inc. |
SAFE AND EFFECTIVE METHOD OF TREATING LUPUS WITH AN ANTI-IL12/IL23 ANTIBODY
|
AR117327A1
(es)
|
2018-12-20 |
2021-07-28 |
23Andme Inc |
Anticuerpos anti-cd96 y métodos de uso de estos
|
CN113286822A
(zh)
|
2018-12-21 |
2021-08-20 |
豪夫迈·罗氏有限公司 |
靶向肿瘤的超激动性cd28抗原结合分子
|
CA3121804A1
(en)
|
2018-12-21 |
2020-06-25 |
Genentech, Inc. |
Methods of producing polypeptides using a cell line resistant to apoptosis
|
BR112021010374A2
(pt)
|
2018-12-21 |
2021-08-24 |
23Andme, Inc. |
Anticorpos anti-il-36 e métodos de uso dos mesmos
|
CN113621062B
(zh)
|
2018-12-21 |
2024-07-02 |
豪夫迈·罗氏有限公司 |
与cd3结合的抗体
|
UA128001C2
(uk)
|
2018-12-21 |
2024-03-06 |
Ф. Хоффманн-Ля Рош Аг |
Націлені на пухлину агоністичні cd28-антигензв'язувальні молекули
|
WO2020127885A1
(en)
|
2018-12-21 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Compositions for treating cancers and resistant cancers
|
MX2021007768A
(es)
|
2018-12-26 |
2021-08-24 |
Xilio Dev Inc |
Anticuerpos anti-ctla4 y metodos de uso de los mismos.
|
JP2022515543A
(ja)
|
2018-12-30 |
2022-02-18 |
エフ.ホフマン-ラ ロシュ アーゲー |
抗ウサギcd19抗体および使用方法
|
CN113574386A
(zh)
|
2019-01-03 |
2021-10-29 |
国家医疗保健研究所 |
用于增强癌症患者的cd8+t细胞依赖性免疫应答的方法和药物组合物
|
WO2020150152A1
(en)
|
2019-01-14 |
2020-07-23 |
Genentech, Inc. |
Methods of treating cancer with a pd-1 axis binding antagonist and an rna vaccine
|
MX2021008537A
(es)
|
2019-01-15 |
2021-11-12 |
Janssen Biotech Inc |
Composiciones de anticuerpos anti-tnf y métodos para el tratamiento de la artritis idiopática juvenil.
|
CN113330027A
(zh)
|
2019-01-23 |
2021-08-31 |
豪夫迈·罗氏有限公司 |
在真核宿主细胞中产生多聚体蛋白质的方法
|
CA3127748A1
(en)
|
2019-01-23 |
2020-07-30 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions for use in methods for the treatment of psoriatic arthritis
|
CN113329770A
(zh)
|
2019-01-24 |
2021-08-31 |
中外制药株式会社 |
新型癌抗原及所述抗原的抗体
|
CA3126727A1
(en)
|
2019-01-28 |
2020-08-06 |
Maple Biotech Llc |
Psmp antagonists for use in treatment of fibrotic disease of the lung, kidney or liver
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
WO2020161083A1
(en)
|
2019-02-04 |
2020-08-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating blood-brain barrier
|
WO2020163589A1
(en)
|
2019-02-08 |
2020-08-13 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
CN115925972A
(zh)
|
2019-02-18 |
2023-04-07 |
Atb治疗公司 |
在植物细胞或整株植物中产生结合物-毒素融合蛋白的方法
|
WO2020169698A1
(en)
|
2019-02-21 |
2020-08-27 |
F. Hoffmann-La Roche Ag |
Sensitization of cancer cells to tnf by bet inhibition
|
WO2020169707A1
(en)
|
2019-02-21 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Foxo1 inhibitor for use in the treatment of latent virus infection
|
JP2022521773A
(ja)
|
2019-02-27 |
2022-04-12 |
ジェネンテック, インコーポレイテッド |
抗tigit抗体と抗cd20抗体又は抗cd38抗体とによる処置のための投薬
|
JP2022523781A
(ja)
|
2019-03-01 |
2022-04-26 |
アロジーン セラピューティクス,インコーポレイテッド |
Dll3標的化キメラ抗原受容体および結合剤
|
EP3935391B1
(en)
|
2019-03-05 |
2024-04-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Biomarkers for renal cell carcinoma
|
TW202101000A
(zh)
|
2019-03-08 |
2021-01-01 |
美商建南德克公司 |
用於偵測且量化膜相關蛋白之方法
|
AU2020236015A1
(en)
|
2019-03-14 |
2021-09-09 |
Genentech, Inc. |
Treatment of cancer with HER2XCD3 bispecific antibodies in combination with anti-HER2 MAB
|
WO2020183418A1
(en)
|
2019-03-14 |
2020-09-17 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-il12/il23 antibody compositions
|
KR20210141998A
(ko)
|
2019-03-14 |
2021-11-23 |
얀센 바이오테크 인코포레이티드 |
항-tnf 항체 조성물의 제조 방법
|
CA3133383A1
(en)
|
2019-03-14 |
2020-09-17 |
Janssen Biotech, Inc. |
Methods for producing anti-tnf antibody compositions
|
EP3938390A1
(en)
|
2019-03-14 |
2022-01-19 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-tnf antibody compositions
|
JP7379654B2
(ja)
|
2019-03-15 |
2023-11-14 |
カーティザン セラピューティクス,インコーポレーテッド |
抗bcmaキメラ抗原受容体
|
EA202192459A1
(ru)
|
2019-03-18 |
2021-11-25 |
Янссен Байотек, Инк. |
Способ лечения псориаза антителом к il12/il23 у субъектов детского возраста
|
CN113613676A
(zh)
|
2019-03-19 |
2021-11-05 |
中外制药株式会社 |
包含对抗原的结合活性因mta而变化的抗原结合结构域的抗原结合分子及用于获得该抗原结合结构域的文库
|
US20220177558A1
(en)
|
2019-03-25 |
2022-06-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Treatment of taupathy disorders by targeting new tau species
|
CN113631910A
(zh)
|
2019-03-29 |
2021-11-09 |
豪夫迈·罗氏有限公司 |
细胞表面蛋白质相互作用的调节剂及其相关方法和组合物
|
WO2020201073A1
(en)
|
2019-03-29 |
2020-10-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the treatment of keloid, hypertrophic scars and/or hyperpigmentation disorders
|
EP3947737A2
(en)
|
2019-04-02 |
2022-02-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of predicting and preventing cancer in patients having premalignant lesions
|
JP2022527345A
(ja)
|
2019-04-03 |
2022-06-01 |
オレガ・バイオテック |
Pd1阻害剤及びil-17b阻害剤に基づく複合療法
|
US20220249458A1
(en)
|
2019-04-04 |
2022-08-11 |
Bayer Aktiengesellschaft |
Agonists Of Adiponectin
|
US20220204610A1
(en)
|
2019-04-09 |
2022-06-30 |
New York Society For The Relief Of The Ruptured And Crippled, Maintaing Hospital For Special Surgery |
Protein binders for irhom2
|
CN113692414A
(zh)
|
2019-04-12 |
2021-11-23 |
豪夫迈·罗氏有限公司 |
使用CEA CD3双特异性抗体和Wnt信号传导抑制剂的癌症治疗
|
EP3952996A1
(en)
|
2019-04-12 |
2022-02-16 |
F. Hoffmann-La Roche AG |
Bispecific antigen binding molecules comprising lipocalin muteins
|
TW202043291A
(zh)
|
2019-04-19 |
2020-12-01 |
美商建南德克公司 |
抗mertk抗體及使用方法
|
MX2021013005A
(es)
|
2019-04-26 |
2021-12-10 |
Allogene Therapeutics Inc |
Metodos de fabricacion de celulas car-t alogenicas.
|
EP3963109A1
(en)
|
2019-04-30 |
2022-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
WO2020227159A2
(en)
|
2019-05-03 |
2020-11-12 |
Flagship Pioneering Innovations V, Inc. |
Methods of modulating immune activity
|
KR20220004744A
(ko)
|
2019-05-03 |
2022-01-11 |
제넨테크, 인크. |
항-pd-l1 항체를 이용하여 암을 치료하는 방법
|
WO2020232169A1
(en)
|
2019-05-14 |
2020-11-19 |
Genentech, Inc. |
Methods of using anti-cd79b immunoconjugates to treat follicular lymphoma
|
SG11202112541RA
(en)
|
2019-05-14 |
2021-12-30 |
Werewolf Therapeutics Inc |
Separation moieties and methods and use thereof
|
MX2021014302A
(es)
|
2019-05-23 |
2022-01-04 |
Janssen Biotech Inc |
Metodo para tratar la enfermedad inflamatoria del intestino con una terapia de combinacion de anticuerpos contra il-23 y tnf alfa.
|
WO2020239934A1
(en)
|
2019-05-28 |
2020-12-03 |
Vib Vzw |
Cd8+ t-cells lacking plexins and their application in cancer treatment
|
WO2020239945A1
(en)
|
2019-05-28 |
2020-12-03 |
Vib Vzw |
Cancer treatment by targeting plexins in the immune compartment
|
US20220323580A1
(en)
|
2019-06-03 |
2022-10-13 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions, and methods for the treatment of psoriatic arthritis
|
KR20220030952A
(ko)
|
2019-06-03 |
2022-03-11 |
얀센 바이오테크 인코포레이티드 |
활성 강직성 척추염의 치료를 위한 항-tnf 항체, 조성물, 및 방법
|
US20220315909A1
(en)
|
2019-06-05 |
2022-10-06 |
Chugai Seiyaku Kabushiki Kaisha |
Protease substrate, and polypeptide including protease cleavage sequence
|
MX2021014433A
(es)
|
2019-06-05 |
2022-03-11 |
Chugai Pharmaceutical Co Ltd |
Molecula de union a sitio de escision de anticuerpo.
|
US20220253669A1
(en)
|
2019-06-07 |
2022-08-11 |
Chugai Seiyaku Kabushiki Kaisha |
Information processing system, information processing method, program, and method for producing antigen-binding molecule or protein
|
CA3140023A1
(en)
|
2019-06-11 |
2020-12-17 |
Alector Llc |
Anti-sortilin antibodies for use in therapy
|
CN114206938A
(zh)
|
2019-06-20 |
2022-03-18 |
国家医疗保健研究所 |
抗蛋白酶nexin-1构象单域抗体及其用途
|
EP3990477A1
(en)
|
2019-06-26 |
2022-05-04 |
F. Hoffmann-La Roche AG |
Fusion of an antibody binding cea and 4-1bbl
|
WO2020260326A1
(en)
|
2019-06-27 |
2020-12-30 |
F. Hoffmann-La Roche Ag |
Novel icos antibodies and tumor-targeted antigen binding molecules comprising them
|
WO2021001289A1
(en)
|
2019-07-02 |
2021-01-07 |
F. Hoffmann-La Roche Ag |
Immunoconjugates comprising a mutant interleukin-2 and an anti-cd8 antibody
|
AR119393A1
(es)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos que se unen a nkg2d
|
US20210030885A1
(en)
|
2019-07-22 |
2021-02-04 |
Seagen Inc. |
Humanized anti-liv1 antibodies for the treatment of cancer
|
PE20220487A1
(es)
|
2019-07-31 |
2022-04-04 |
Alector Llc |
Anticuerpos anti-ms4a4a y metodos de uso de los mismos
|
EP4004045A1
(en)
|
2019-07-31 |
2022-06-01 |
F. Hoffmann-La Roche AG |
Antibodies binding to gprc5d
|
PE20220394A1
(es)
|
2019-07-31 |
2022-03-18 |
Hoffmann La Roche |
Anticuerpos que se fijan a gprc5d
|
CN114401743A
(zh)
|
2019-08-02 |
2022-04-26 |
法国国家健康和医学研究院 |
中和颗粒酶b用于向经历过心肌梗塞的受试者提供心脏保护
|
WO2021028752A1
(en)
|
2019-08-15 |
2021-02-18 |
Janssen Biotech, Inc. |
Anti-tfn antibodies for treating type i diabetes
|
WO2021048292A1
(en)
|
2019-09-11 |
2021-03-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
EP4028054A1
(en)
|
2019-09-12 |
2022-07-20 |
Genentech, Inc. |
Compositions and methods of treating lupus nephritis
|
WO2021055816A1
(en)
|
2019-09-18 |
2021-03-25 |
Molecular Templates, Inc. |
Pd-l1 binding molecules comprising shiga toxin a subunit scaffolds
|
CA3150999A1
(en)
|
2019-09-18 |
2021-03-25 |
James Thomas Koerber |
Anti-klk7 antibodies, anti-klk5 antibodies, multispecific anti-klk5/klk7 antibodies, and methods of use
|
MX2022003266A
(es)
|
2019-09-20 |
2022-04-11 |
Genentech Inc |
Dosis para anticuerpos anti-triptasa.
|
JP7122354B2
(ja)
|
2019-09-24 |
2022-08-19 |
財團法人工業技術研究院 |
抗tigit抗体および使用方法
|
EP4048693A1
(en)
|
2019-09-27 |
2022-08-31 |
F. Hoffmann-La Roche AG |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
CN114829401A
(zh)
|
2019-09-27 |
2022-07-29 |
南京金斯瑞生物科技有限公司 |
抗vhh域抗体及其用途
|
JP2022550325A
(ja)
|
2019-09-27 |
2022-12-01 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
抗ミュラー管抑制物質抗体およびその使用
|
WO2021058729A1
(en)
|
2019-09-27 |
2021-04-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-müllerian inhibiting substance type i receptor antibodies and uses thereof
|
WO2021063968A1
(en)
|
2019-09-30 |
2021-04-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method and composition for diagnosing chronic obstructive pulmonary disease
|
WO2021064009A1
(en)
|
2019-09-30 |
2021-04-08 |
Scirhom Gmbh |
Protein binders to irhom2 epitopes
|
TW202128756A
(zh)
|
2019-10-02 |
2021-08-01 |
德商百靈佳殷格翰國際股份有限公司 |
用於癌症治療之多重專一性結合蛋白
|
US20220354811A1
(en)
|
2019-10-03 |
2022-11-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating macrophages polarization
|
WO2021064184A1
(en)
|
2019-10-04 |
2021-04-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
JP7413519B2
(ja)
|
2019-10-18 |
2024-01-15 |
ジェネンテック, インコーポレイテッド |
びまん性大細胞型b細胞リンパ腫を処置するための抗cd79b免疫抱合体の使用方法
|
WO2021078359A1
(en)
|
2019-10-21 |
2021-04-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of inhibitors of cubilin for the treatment of chronic kidney diseases
|
BR112022008652A2
(pt)
|
2019-11-05 |
2022-07-19 |
Hoffmann La Roche |
Anticorpos biespecíficos hla-a2/wt1 x cd3, uso de um anticorpo biespecífico, método para tratar câncer em um indivíduo, kit e invenção
|
MX2022005400A
(es)
|
2019-11-06 |
2022-05-24 |
Genentech Inc |
Metodos de diagnostico y terapeuticos para el tratamiento de canceres hematologicos.
|
BR112022008756A2
(pt)
|
2019-11-07 |
2022-07-26 |
Eisai R&D Man Co Ltd |
Conjugados anticorpo-fármaco anti-mesotelina eribulina e métodos de uso
|
EP4058469A1
(en)
|
2019-11-12 |
2022-09-21 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
New serological marker for the latent form of toxoplasmosis
|
MX2022005666A
(es)
|
2019-11-14 |
2022-10-07 |
Werewolf Therapeutics Inc |
Polipeptidos de citocina activables y metodos de uso de los mismos.
|
AU2020381534A1
(en)
|
2019-11-15 |
2022-06-23 |
Pliant Therapeutics, Inc. |
Compositions and methods for activation of integrins
|
WO2021110796A1
(en)
|
2019-12-04 |
2021-06-10 |
Bayer Aktiengesellschaft |
Inhibitors of shp2
|
EP4072682A1
(en)
|
2019-12-09 |
2022-10-19 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Antibodies having specificity to her4 and uses thereof
|
GB201918279D0
(en)
|
2019-12-12 |
2020-01-29 |
Vib Vzw |
Glycosylated single chain immunoglobulin domains
|
EP4072680A1
(en)
|
2019-12-13 |
2022-10-19 |
Alector LLC |
Anti-mertk antibodies and methods of use thereof
|
US11845799B2
(en)
|
2019-12-13 |
2023-12-19 |
Genentech, Inc. |
Anti-Ly6G6D antibodies and methods of use
|
EP4076434A1
(en)
|
2019-12-17 |
2022-10-26 |
Flagship Pioneering Innovations V, Inc. |
Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly
|
JP7296467B2
(ja)
|
2019-12-18 |
2023-06-22 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Hla-a2/mage-a4に結合する抗体
|
CN115298213A
(zh)
|
2019-12-19 |
2022-11-04 |
奎多公司 |
单克隆抗体融合
|
CA3164797A1
(en)
|
2019-12-23 |
2021-07-01 |
Eisai R&D Management Co., Ltd. |
Method of producing eribulin based antibody-drug conjugate
|
CN115515678A
(zh)
|
2019-12-23 |
2022-12-23 |
基因泰克公司 |
载脂蛋白l1特异性抗体及其使用方法
|
KR20240035914A
(ko)
|
2019-12-27 |
2024-03-18 |
추가이 세이야쿠 가부시키가이샤 |
항ctla-4 항체 및 그의 사용
|
EP4087866A1
(en)
|
2020-01-09 |
2022-11-16 |
F. Hoffmann-La Roche AG |
New 4-1bbl trimer-containing antigen binding molecules
|
CN110818795B
(zh)
|
2020-01-10 |
2020-04-24 |
上海复宏汉霖生物技术股份有限公司 |
抗tigit抗体和使用方法
|
US20230076415A1
(en)
|
2020-01-17 |
2023-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
WO2022050954A1
(en)
|
2020-09-04 |
2022-03-10 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
WO2021194481A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
CA3164559A1
(en)
|
2020-01-31 |
2021-08-05 |
Lars Mueller |
Methods of inducing neoepitope-specific t cells with a pd-1 axis binding antagonist and an rna vaccine
|
EP4100435A1
(en)
|
2020-02-05 |
2022-12-14 |
Larimar Therapeutics, Inc. |
Tat peptide binding proteins and uses thereof
|
AU2021218927A1
(en)
|
2020-02-10 |
2022-09-22 |
Shanghai Escugen Biotechnology Co., Ltd. |
Claudin 18.2 antibody and use thereof
|
US20230312704A1
(en)
|
2020-02-10 |
2023-10-05 |
Shanghai Escugen Biotechnology Co., Ltd. |
Cldn18.2 antibody and use thereof
|
TW202144395A
(zh)
|
2020-02-12 |
2021-12-01 |
日商中外製藥股份有限公司 |
用於癌症之治療的抗cd137抗原結合分子
|
CN113248611A
(zh)
|
2020-02-13 |
2021-08-13 |
湖南华康恒健生物技术有限公司 |
抗bcma抗体、其药物组合物及应用
|
WO2021170750A1
(en)
|
2020-02-28 |
2021-09-02 |
Orega Biotech |
Combination therapies based on ctla4 and il-17b inhibitors
|
CN115605507A
(zh)
|
2020-03-13 |
2023-01-13 |
基因泰克公司(Us) |
抗白介素-33抗体及其用途
|
BR112022018657A2
(pt)
|
2020-03-19 |
2022-11-01 |
Genentech Inc |
Anticorpos, ácido nucleico, célula hospedeira, imunoconjugado, formulação farmacêutica, usos de um anticorpo, métodos de produção de um anticorpo e de tratamento de um indivíduo, métodos para inibir a sinalização de smad e para diagnosticar um indivíduo como tendo ssc e kit
|
WO2021194913A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Tie2-binding agents and methods of use
|
US20210309989A1
(en)
|
2020-03-26 |
2021-10-07 |
Genentech, Inc. |
Modified mammalian cells
|
BR112022017526A2
(pt)
|
2020-03-31 |
2022-10-18 |
Chugai Pharmaceutical Co Ltd |
Método para produzir moléculas de ligação de antígeno multiespecíficas
|
CA3178461A1
(en)
|
2020-03-31 |
2021-10-07 |
Biotalys NV |
Anti-fungal polypeptides
|
CN116075525A
(zh)
|
2020-03-31 |
2023-05-05 |
艾莱克特有限责任公司 |
抗mertk抗体及其使用方法
|
AR121706A1
(es)
|
2020-04-01 |
2022-06-29 |
Hoffmann La Roche |
Moléculas de unión a antígeno biespecíficas dirigidas a ox40 y fap
|
CA3170570A1
(en)
|
2020-04-01 |
2021-10-07 |
James J. KOBIE |
Monoclonal antibodies against the hemagglutinin (ha) and neuraminidase (na) of influenza h3n2 viruses
|
WO2021198511A1
(en)
|
2020-04-03 |
2021-10-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treatment of sars-cov-2 infection
|
EP4127724A1
(en)
|
2020-04-03 |
2023-02-08 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
KR20230004494A
(ko)
|
2020-04-15 |
2023-01-06 |
에프. 호프만-라 로슈 아게 |
면역접합체
|
CN113527488A
(zh)
|
2020-04-22 |
2021-10-22 |
迈威(上海)生物科技股份有限公司 |
一种靶向人程序性死亡配体1(pd-l1)的单可变域抗体及其衍生物
|
CA3178472A1
(en)
|
2020-04-24 |
2021-10-28 |
F. Hoffmann-La Roche Ag |
Enzyme and pathway modulation with sulfhydryl compounds and their derivatives
|
JP2023522930A
(ja)
|
2020-04-24 |
2023-06-01 |
ジェネンテック, インコーポレイテッド |
抗CD79b免疫抱合体の使用方法
|
TW202206100A
(zh)
|
2020-04-27 |
2022-02-16 |
美商西健公司 |
癌症之治療
|
KR20230002261A
(ko)
|
2020-04-28 |
2023-01-05 |
더 락커펠러 유니버시티 |
항-sars-cov-2 중화 항체 및 이의 사용 방법
|
CN115885050A
(zh)
|
2020-04-28 |
2023-03-31 |
基因泰克公司 |
用于非小细胞肺癌免疫疗法的方法和组合物
|
MX2022013768A
(es)
|
2020-05-03 |
2023-01-05 |
Levena Suzhou Biopharma Co Ltd |
Conjugados anticuerpo-fármaco (adc) que comprenden un anticuerpo anti-trop-2, composiciones que comprenden dichos adc, así como métodos para fabricar y utilizar los mismos.
|
WO2021224401A1
(en)
|
2020-05-07 |
2021-11-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for determining a reference range of β-galactose exposure platelet
|
KR20230008751A
(ko)
|
2020-05-12 |
2023-01-16 |
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) |
피부 t-세포 림프종 및 tfh 유래된 림프종을 치료하는 신규한 방법
|
WO2021229104A1
(en)
|
2020-05-15 |
2021-11-18 |
Université de Liège |
Anti-cd38 single-domain antibodies in disease monitoring and treatment
|
US20230212260A1
(en)
|
2020-05-15 |
2023-07-06 |
Apogenix Ag |
Multi-specific immune modulators
|
CA3180665A1
(en)
|
2020-05-19 |
2021-11-25 |
Boehringer Ingelheim International Gmbh |
Binding molecules for the treatment of cancer
|
WO2021236225A1
(en)
|
2020-05-20 |
2021-11-25 |
Takeda Vaccines, Inc. |
Method for detection of zika virus specific antibodies
|
WO2021234104A1
(en)
|
2020-05-20 |
2021-11-25 |
Institut Curie |
Synthetic single domain library
|
JP2023526493A
(ja)
|
2020-05-20 |
2023-06-21 |
タケダ ワクチン,インコーポレイテッド |
ジカウイルス特異的抗体の検出方法
|
EP4154003A1
(en)
|
2020-05-20 |
2023-03-29 |
Takeda Vaccines, Inc. |
Method for determining the potency of antigens
|
CA3182333A1
(en)
|
2020-05-20 |
2021-11-25 |
Institut Curie |
Single domain antibodies and their use in cancer therapies
|
CN116323665A
(zh)
|
2020-05-29 |
2023-06-23 |
23和我公司 |
抗cd200r1抗体及其使用方法
|
IL298053A
(en)
|
2020-06-05 |
2023-01-01 |
Eisai R&D Man Co Ltd |
Antibody-drug conjugates against bcma and methods of use
|
US20230235326A1
(en)
|
2020-06-05 |
2023-07-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for treating ocular diseases
|
JP2023527918A
(ja)
|
2020-06-08 |
2023-06-30 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
抗hbv抗体及び使用方法
|
MX2022015651A
(es)
|
2020-06-11 |
2023-01-16 |
Genentech Inc |
Conjugados de nanolipoproteina-polipeptido y composiciones, sistemas y procedimientos mediante el uso de los mismos.
|
WO2021252977A1
(en)
|
2020-06-12 |
2021-12-16 |
Genentech, Inc. |
Methods and compositions for cancer immunotherapy
|
MX2022015877A
(es)
|
2020-06-16 |
2023-01-24 |
Genentech Inc |
Metodos y composiciones para tratar cancer de mama triple negativo.
|
CN116157510A
(zh)
|
2020-06-17 |
2023-05-23 |
詹森生物科技公司 |
用于制造多能干细胞的材料和方法
|
US20210395366A1
(en)
|
2020-06-18 |
2021-12-23 |
Genentech, Inc. |
Treatment with anti-tigit antibodies and pd-1 axis binding antagonists
|
BR112022025809A2
(pt)
|
2020-06-19 |
2023-01-10 |
Hoffmann La Roche |
Anticorpos, polinucleotídeo isolado, célula hospedeira, método para produzir um anticorpo, uso do anticorpo, método para tratar uma doença e invenção
|
KR20230025665A
(ko)
|
2020-06-19 |
2023-02-22 |
에프. 호프만-라 로슈 아게 |
Cd3에 결합하는 항체
|
CN115916825A
(zh)
|
2020-06-19 |
2023-04-04 |
豪夫迈·罗氏有限公司 |
与cd3和cd19结合的抗体
|
CA3177239A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Protease-activated t cell bispecific antibodies
|
WO2021255146A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and cea
|
CN116234824A
(zh)
|
2020-06-22 |
2023-06-06 |
阿尔米雷尔有限公司 |
抗il-36抗体及其使用方法
|
MX2022015795A
(es)
|
2020-06-23 |
2023-01-24 |
Hoffmann La Roche |
Moleculas agonistas de union al antigeno cd28 que se dirigen a her2.
|
US20220041672A1
(en)
|
2020-06-24 |
2022-02-10 |
Genentech, Inc. |
Apoptosis resistant cell lines
|
WO2021260064A1
(en)
|
2020-06-25 |
2021-12-30 |
F. Hoffmann-La Roche Ag |
Anti-cd3/anti-cd28 bispecific antigen binding molecules
|
EP4172323A1
(en)
|
2020-06-29 |
2023-05-03 |
Flagship Pioneering Innovations V, Inc. |
Viruses engineered to promote thanotransmission and their use in treating cancer
|
US20230265211A1
(en)
|
2020-06-29 |
2023-08-24 |
Inserm (Institut National De La Santé Et De Ls Recherche Médicale) |
Anti-protein s single-domain antibodies and polypeptides comprising thereof
|
WO2022008597A1
(en)
|
2020-07-08 |
2022-01-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of infectious diseases
|
WO2022015726A1
(en)
|
2020-07-13 |
2022-01-20 |
Genentech, Inc. |
Cell-based methods for predicting polypeptide immunogenicity
|
BR112023000839A2
(pt)
|
2020-07-17 |
2023-02-07 |
Genentech Inc |
Anticorpos isolados, ácido nucleico isolado, célula hospedeira, métodos para produzir um anticorpo que se liga a notch2 humano, para tratar um indivíduo com uma doença pulmonar muco-obstrutiva e para reduzir o número de células secretoras em um indivíduo, composição farmacêutica, anticorpo, anticorpo para uso e uso do anticorpo
|
CA3188649A1
(en)
|
2020-07-21 |
2022-01-27 |
Genentech, Inc. |
Antibody-conjugated chemical inducers of degradation of brm and methods thereof
|
US20230266332A1
(en)
|
2020-07-28 |
2023-08-24 |
Inserm (Institut National De La Santè Et De La Recherch Médicale) |
Methods and compositions for preventing and treating a cancer
|
GB2597532A
(en)
|
2020-07-28 |
2022-02-02 |
Femtogenix Ltd |
Cytotoxic compounds
|
US20230323299A1
(en)
|
2020-08-03 |
2023-10-12 |
Inserm (Institut National De La Santé Et De La Recherch Médicale) |
Population of treg cells functionally committed to exert a regulatory activity and their use for adoptive therapy
|
WO2022031948A1
(en)
|
2020-08-07 |
2022-02-10 |
Genentech, Inc. |
T cell-based methods for predicting polypeptide immunogenicity
|
JP2023538563A
(ja)
|
2020-08-17 |
2023-09-08 |
エーティービー セラピューティクス |
リボトキシンまたはRNAseを含む組換え免疫毒素
|
CN114106173A
(zh)
|
2020-08-26 |
2022-03-01 |
上海泰槿生物技术有限公司 |
抗ox40抗体、其药物组合物及应用
|
JP2023539201A
(ja)
|
2020-08-28 |
2023-09-13 |
ジェネンテック, インコーポレイテッド |
宿主細胞タンパク質のCRISPR/Cas9マルチプレックスノックアウト
|
JP2023539279A
(ja)
|
2020-08-31 |
2023-09-13 |
ジェネンテック, インコーポレイテッド |
抗体を産生するための方法
|
IL301269A
(en)
|
2020-09-14 |
2023-05-01 |
Ichnos Sciences S A |
Antibodies that bind to IL1RAP and their uses
|
WO2022063803A1
(en)
|
2020-09-24 |
2022-03-31 |
F. Hoffmann-La Roche Ag |
Prevention or mitigation of t-cell bispecific antibody-related adverse effects
|
EP4216943A1
(en)
|
2020-09-24 |
2023-08-02 |
Vib Vzw |
Combination of p2y6 inhibitors and immune checkpoint inhibitors
|
WO2022063957A1
(en)
|
2020-09-24 |
2022-03-31 |
Vib Vzw |
Biomarker for anti-tumor therapy
|
KR20230079154A
(ko)
|
2020-09-28 |
2023-06-05 |
씨젠 인크. |
암 치료를 위한 인간화 항-liv1 항체
|
WO2022064049A1
(en)
|
2020-09-28 |
2022-03-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method for diagnosing brucella infection
|
WO2022072523A1
(en)
|
2020-09-30 |
2022-04-07 |
Seagen Inc. |
Uveal melanoma treatment using sea-cd40
|
WO2022076462A1
(en)
|
2020-10-05 |
2022-04-14 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2022076865A1
(en)
|
2020-10-09 |
2022-04-14 |
Takeda Vaccines, Inc. |
Methods for determining complement-fixing antibodies
|
WO2022079270A1
(en)
|
2020-10-16 |
2022-04-21 |
Université D'aix-Marseille |
Anti-gpc4 single domain antibodies
|
TW202233671A
(zh)
|
2020-10-20 |
2022-09-01 |
美商建南德克公司 |
Peg結合抗mertk抗體及其使用方法
|
KR20230091871A
(ko)
|
2020-10-20 |
2023-06-23 |
에프. 호프만-라 로슈 아게 |
Pd-1 축 결합 길항제 및 lrrk2 억제제의 병용 요법
|
WO2022084300A1
(en)
|
2020-10-20 |
2022-04-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosis and monitoring form of coronavirus infection
|
AR123862A1
(es)
|
2020-10-21 |
2023-01-18 |
Boehringer Ingelheim Int |
Moléculas de unión biespecíficas anti-vegf y anti-trkb para el tratamiento de enfermedades oculares
|
WO2022084531A1
(en)
|
2020-10-23 |
2022-04-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating glioma
|
WO2022093981A1
(en)
|
2020-10-28 |
2022-05-05 |
Genentech, Inc. |
Combination therapy comprising ptpn22 inhibitors and pd-l1 binding antagonists
|
WO2022090439A1
(en)
|
2020-10-30 |
2022-05-05 |
F. Hoffmann-La Roche Ag |
TREATMENT OF CANCER USING A CEA CD3 BISPECIFIC ANTIBODY AND A TGFβ SIGNALING INHIBITOR
|
WO2022098638A2
(en)
|
2020-11-04 |
2022-05-12 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
|
JP2023548878A
(ja)
|
2020-11-04 |
2023-11-21 |
ザ ロックフェラー ユニバーシティー |
中和抗sars-cov-2抗体
|
KR20230100732A
(ko)
|
2020-11-04 |
2023-07-05 |
제넨테크, 인크. |
항-cd20/항-cd3 이중특이성 항체의 피하 투여
|
KR20230133837A
(ko)
|
2020-11-04 |
2023-09-19 |
마이얼로이드 테라퓨틱스, 인크. |
조작된 키메라 융합 단백질 조성물 및 그의 사용 방법
|
KR20230095113A
(ko)
|
2020-11-04 |
2023-06-28 |
제넨테크, 인크. |
항-cd20/항-cd3 이중특이적 항체들과 항-cd79b 항체 약물 접합체들을 이용한 치료를 위한 투약
|
US20240002519A1
(en)
|
2020-11-05 |
2024-01-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of il-6 inhibitors for the treatment of acute chest syndrome in patients suffering from sickle cell disease
|
JP2023547523A
(ja)
|
2020-11-10 |
2023-11-10 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
T細胞係合剤関連の有害作用の防止又は軽減
|
EP4244254A1
(en)
|
2020-11-16 |
2023-09-20 |
F. Hoffmann-La Roche AG |
Combination therapy with fap-targeted cd40 agonists
|
WO2022101481A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating uveal melanoma
|
CA3200954A1
(en)
|
2020-11-16 |
2022-05-19 |
F. Hoffmann-La Roche Ag |
Fab high mannose glycoforms
|
WO2022109441A1
(en)
|
2020-11-23 |
2022-05-27 |
Genentech, Inc. |
Methods for modulating host cell surface interactions with sars-cov-2
|
AU2021386240A1
(en)
|
2020-11-27 |
2023-06-29 |
Genentech, Inc. |
Methods for modulating host cell surface interactions with human cytomegalovirus
|
EP4256349A1
(en)
|
2020-12-01 |
2023-10-11 |
Genentech, Inc. |
Biological vesicles displaying cell surface proteins and methods related to same
|
WO2022120352A1
(en)
|
2020-12-02 |
2022-06-09 |
Alector Llc |
Methods of use of anti-sortilin antibodies
|
EP4263609A1
(en)
|
2020-12-17 |
2023-10-25 |
F. Hoffmann-La Roche AG |
Anti-hla-g antibodies and use thereof
|
US20240058279A1
(en)
|
2020-12-21 |
2024-02-22 |
Flagship Pioneering Innovations V, Inc. |
Use of cell turnover factors for increasing tissue regeneration
|
MX2023007846A
(es)
|
2021-01-06 |
2023-07-07 |
Hoffmann La Roche |
Tratamiento conjunto que usa un anticuerpo biespecifico contra pd1-lag3 y un anticuerpo biespecifico de linfocitos t cd20.
|
WO2022153195A1
(en)
|
2021-01-13 |
2022-07-21 |
Memorial Sloan Kettering Cancer Center |
Anti-dll3 antibody-drug conjugate
|
WO2022153212A1
(en)
|
2021-01-13 |
2022-07-21 |
Axon Neuroscience Se |
Antibodies neutralizing sars-cov-2
|
CN117425501A
(zh)
|
2021-01-13 |
2024-01-19 |
纪念斯隆凯特琳癌症中心 |
抗体-吡咯并苯二氮䓬衍生物缀合物
|
JP2024505428A
(ja)
|
2021-01-14 |
2024-02-06 |
アンスティテュ キュリー |
Her2単一ドメイン抗体バリアントおよびそのcar
|
EP4277926A1
(en)
|
2021-01-15 |
2023-11-22 |
The Rockefeller University |
Neutralizing anti-sars-cov-2 antibodies
|
AR124681A1
(es)
|
2021-01-20 |
2023-04-26 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
JP2024504390A
(ja)
|
2021-01-22 |
2024-01-31 |
バイワンキュア セラピューティクス, インコーポレイテッド |
抗her-2/trop-2構築物及びその使用
|
JP2024504475A
(ja)
|
2021-01-28 |
2024-01-31 |
南京▲樺▼冠生物技▲術▼有限公司 |
複合体およびその使用
|
WO2022175392A1
(en)
|
2021-02-17 |
2022-08-25 |
Vib Vzw |
Inhibition of slc4a4 in the treatment of cancer
|
AU2022224636A1
(en)
|
2021-02-19 |
2023-09-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies that neutralize sars-cov-2
|
WO2022178090A2
(en)
|
2021-02-19 |
2022-08-25 |
Theripion, Inc. |
Dnase fusion polypeptides and related compositions and methods
|
TW202241941A
(zh)
|
2021-02-22 |
2022-11-01 |
美商建南德克公司 |
調節宿主細胞表面與疱疹病毒交互作用之方法
|
EP4298123A2
(en)
|
2021-02-26 |
2024-01-03 |
Bayer Aktiengesellschaft |
Inhibitors of il-11 or il-11ra for use in the treatment of abnormal uterine bleeding
|
EP4301467A1
(en)
|
2021-03-01 |
2024-01-10 |
Xilio Development, Inc. |
Combination of ctla4 and pd1/pdl1 antibodies for treating cancer
|
CN116917325A
(zh)
|
2021-03-01 |
2023-10-20 |
西里欧发展公司 |
用于治疗癌症的被掩蔽的ctla4和pd1/pdl1抗体的组合
|
JP2024510415A
(ja)
|
2021-03-01 |
2024-03-07 |
スキロム ゲゼルシャフト ミット ベシュレンクテル ハフツング |
iRhom2に対するヒト化抗体
|
CN117440832A
(zh)
|
2021-03-03 |
2024-01-23 |
索伦托药业有限公司 |
包括抗bcma抗体的抗体-药物缀合物
|
US20220298236A1
(en)
|
2021-03-12 |
2022-09-22 |
Janssen Biotech, Inc. |
Safe and Effective Method of Treating Psoriatic Arthritis with Anti-IL23 Specific Antibody
|
EP4305062A1
(en)
|
2021-03-12 |
2024-01-17 |
Janssen Biotech, Inc. |
Method of treating psoriatic arthritis patients with inadequate response to tnf therapy with anti-il23 specific antibody
|
WO2022192647A1
(en)
|
2021-03-12 |
2022-09-15 |
Genentech, Inc. |
Anti-klk7 antibodies, anti-klk5 antibodies, multispecific anti-klk5/klk7 antibodies, and methods of use
|
BR112023018621A2
(pt)
|
2021-03-15 |
2023-10-24 |
Hoffmann La Roche |
Métodos para tratar nefrite lúpica, esgotar células b periféricas, kits para tratar nefrite lúpica e anticorpos anti-cd20 tipo ii
|
EP4308242A1
(en)
|
2021-03-17 |
2024-01-24 |
Molecular Templates, Inc. |
Pd-l1 binding proteins comprising shiga toxin a subunit scaffolds and cd8+ t cell antigens
|
EP4308133A2
(en)
|
2021-03-17 |
2024-01-24 |
Myeloid Therapeutics, Inc. |
Engineered chimeric fusion protein compositions and methods of use thereof
|
BR112023017490A2
(pt)
|
2021-03-17 |
2023-11-07 |
Receptos Llc |
Métodos de tratamento de dermatite atópica com anticorpos anti il-13
|
US20240165094A1
(en)
|
2021-03-17 |
2024-05-23 |
Institut National de la Santé et de la Recherche Médicale |
Methods and compositions for treating melanoma
|
EP4308606A1
(en)
|
2021-03-18 |
2024-01-24 |
Alector LLC |
Anti-tmem106b antibodies and methods of use thereof
|
WO2022197877A1
(en)
|
2021-03-19 |
2022-09-22 |
Genentech, Inc. |
Methods and compositions for time delayed bio-orthogonal release of cytotoxic agents
|
EP4314063A1
(en)
|
2021-03-23 |
2024-02-07 |
Alector LLC |
Anti-tmem106b antibodies for treating and preventing coronavirus infections
|
EP4313317A1
(en)
|
2021-03-23 |
2024-02-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the diagnosis and treatment of t cell-lymphomas
|
WO2022207652A1
(en)
|
2021-03-29 |
2022-10-06 |
Scirhom Gmbh |
Methods of treatment using protein binders to irhom2 epitopes
|
CN117157312A
(zh)
|
2021-03-30 |
2023-12-01 |
豪夫迈·罗氏有限公司 |
蛋白酶活化的多肽
|
AU2022246895A1
(en)
|
2021-03-31 |
2023-10-19 |
Flagship Pioneering Innovations V, Inc. |
Thanotransmission polypeptides and their use in treating cancer
|
CN117597359A
(zh)
|
2021-04-08 |
2024-02-23 |
马伦戈治疗公司 |
与tcr结合的多功能分子及其用途
|
WO2022214681A1
(en)
|
2021-04-09 |
2022-10-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the treatment of anaplastic large cell lymphoma
|
KR20230170672A
(ko)
|
2021-04-14 |
2023-12-19 |
빌라리스 테라퓨틱스 인코포레이티드 |
항-cd122 항체 및 이의 용도
|
AR125344A1
(es)
|
2021-04-15 |
2023-07-05 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-c1s
|
EP4326855A1
(en)
|
2021-04-19 |
2024-02-28 |
Genentech, Inc. |
Modified mammalian cells
|
EP4326871A1
(en)
|
2021-04-19 |
2024-02-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of splice switching oligonucleotides for exon skipping-mediated knockdown of pim2
|
WO2022223791A1
(en)
|
2021-04-23 |
2022-10-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cell senescence accumulation related disease
|
WO2022223651A1
(en)
|
2021-04-23 |
2022-10-27 |
F. Hoffmann-La Roche Ag |
Prevention or mitigation of nk cell engaging agent-related adverse effects
|
AU2021443863A1
(en)
|
2021-04-30 |
2023-10-26 |
F. Hoffmann-La Roche Ag |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibody
|
TW202243689A
(zh)
|
2021-04-30 |
2022-11-16 |
瑞士商赫孚孟拉羅股份公司 |
抗cd20/抗cd3雙特異性抗體及抗cd78b抗體藥物結合物的組合治療之給藥
|
US20240218057A1
(en)
|
2021-05-06 |
2024-07-04 |
The Rockefeller University |
Neutralizing anti- sars-cov-2 antibodies and methods of use thereof
|
IL308351A
(en)
|
2021-05-12 |
2024-01-01 |
Genentech Inc |
Methods for using anti-CD79B immunoconjugates to treat diffuse large B-cell lymphoma
|
US20220389097A1
(en)
|
2021-05-14 |
2022-12-08 |
Genentech Inc. |
Agonists of TREM2
|
WO2022242892A1
(en)
|
2021-05-17 |
2022-11-24 |
Université de Liège |
Anti-cd38 single-domain antibodies in disease monitoring and treatment
|
WO2022243261A1
(en)
|
2021-05-19 |
2022-11-24 |
F. Hoffmann-La Roche Ag |
Agonistic cd40 antigen binding molecules targeting cea
|
JP2024521107A
(ja)
|
2021-05-21 |
2024-05-28 |
ジェネンテック, インコーポレイテッド |
目的の組換え産物を産生するための修飾細胞
|
EP4347657A1
(en)
|
2021-05-25 |
2024-04-10 |
Seagen Inc. |
Methods of quantifying anti-cd40 antibodies
|
TW202306979A
(zh)
|
2021-05-26 |
2023-02-16 |
美商建南德克公司 |
調節人類巨細胞病毒與宿主細胞表面交互作用之方法
|
AR126009A1
(es)
|
2021-06-02 |
2023-08-30 |
Hoffmann La Roche |
Moléculas agonistas de unión al antígeno cd28 que se dirigen a epcam
|
TW202306994A
(zh)
|
2021-06-04 |
2023-02-16 |
日商中外製藥股份有限公司 |
抗ddr2抗體及其用途
|
AU2022284373A1
(en)
|
2021-06-04 |
2024-01-04 |
Boehringer Ingelheim International Gmbh |
Anti-sirp-alpha antibodies
|
IL308015A
(en)
|
2021-06-09 |
2023-12-01 |
Hoffmann La Roche |
A combination of a specific BRAF inhibitor (paradox breaker) and a PD-1 spindle-binding antagonist for use in cancer treatment
|
WO2022266221A1
(en)
|
2021-06-16 |
2022-12-22 |
Alector Llc |
Monovalent anti-mertk antibodies and methods of use thereof
|
WO2022266223A1
(en)
|
2021-06-16 |
2022-12-22 |
Alector Llc |
Bispecific anti-mertk and anti-pdl1 antibodies and methods of use thereof
|
WO2022263507A1
(en)
|
2021-06-17 |
2022-12-22 |
Boehringer Ingelheim International Gmbh |
Novel tri-specific binding molecules
|
US20230174651A1
(en)
|
2021-06-23 |
2023-06-08 |
Janssen Biotech, Inc. |
Materials and methods for hinge regions in functional exogenous receptors
|
BR112023022992A2
(pt)
|
2021-06-25 |
2024-01-23 |
Chugai Pharmaceutical Co Ltd |
Anticorpo anti-ctla-4
|
IL308633A
(en)
|
2021-06-25 |
2024-01-01 |
Chugai Pharmaceutical Co Ltd |
Use of anti-CTLA-4 antibodies
|
WO2023278641A1
(en)
|
2021-06-29 |
2023-01-05 |
Flagship Pioneering Innovations V, Inc. |
Immune cells engineered to promote thanotransmission and uses thereof
|
EP4363449A2
(en)
|
2021-07-02 |
2024-05-08 |
Genentech, Inc. |
Methods and compositions for treating cancer
|
EP4367138A1
(en)
|
2021-07-09 |
2024-05-15 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-il12/il23 antibody compositions
|
EP4367130A1
(en)
|
2021-07-09 |
2024-05-15 |
Luxembourg Institute of Health (LIH) |
Dimeric protein complexes and uses thereof
|
WO2023281462A1
(en)
|
2021-07-09 |
2023-01-12 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-tnf antibody compositions
|
CN117957251A
(zh)
|
2021-07-09 |
2024-04-30 |
詹森生物科技公司 |
用于制备抗tnf抗体组合物的制造方法
|
EP4370550A1
(en)
|
2021-07-12 |
2024-05-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of il-36 inhibitors for the treatment of netherton syndrome
|
TW202309097A
(zh)
|
2021-07-14 |
2023-03-01 |
美商建南德克公司 |
抗c-c模體趨化因子受體8(ccr8)抗體及其使用方法
|
EP4373859A1
(en)
|
2021-07-22 |
2024-05-29 |
F. Hoffmann-La Roche AG |
Heterodimeric fc domain antibodies
|
EP4373576A1
(en)
|
2021-07-22 |
2024-05-29 |
Genentech, Inc. |
Brain targeting compositions and methods of use thereof
|
CN117715936A
(zh)
|
2021-07-28 |
2024-03-15 |
豪夫迈·罗氏有限公司 |
用于治疗癌症的方法和组合物
|
CN117813320A
(zh)
|
2021-07-30 |
2024-04-02 |
Inserm(法国国家健康医学研究院) |
嵌合蛋白和免疫治疗方法
|
EP4377348A1
(en)
|
2021-07-30 |
2024-06-05 |
Seagen Inc. |
Treatment for cancer
|
EP4380980A1
(en)
|
2021-08-03 |
2024-06-12 |
F. Hoffmann-La Roche AG |
Bispecific antibodies and methods of use
|
CN117897409A
(zh)
|
2021-08-13 |
2024-04-16 |
基因泰克公司 |
抗类胰蛋白酶抗体的给药
|
AU2022332303A1
(en)
|
2021-08-27 |
2024-02-01 |
Genentech, Inc. |
Methods of treating tau pathologies
|
TW202325727A
(zh)
|
2021-08-30 |
2023-07-01 |
美商建南德克公司 |
抗聚泛素多特異性抗體
|
TW202313695A
(zh)
|
2021-09-15 |
2023-04-01 |
法商感應檢查療法公司 |
抗btn3a抗體在製備用於治療腫瘤的藥物的用途
|
WO2023053282A1
(ja)
|
2021-09-29 |
2023-04-06 |
中外製薬株式会社 |
がんの治療に用いるための細胞傷害誘導治療剤
|
WO2023056403A1
(en)
|
2021-09-30 |
2023-04-06 |
Genentech, Inc. |
Methods for treatment of hematologic cancers using anti-tigit antibodies, anti-cd38 antibodies, and pd-1 axis binding antagonists
|
WO2023052541A1
(en)
|
2021-09-30 |
2023-04-06 |
Imcheck Therapeutics |
Combination of an anti-btn3a activating antibody and an il-2 agonist for use in therapy
|
TW202330038A
(zh)
|
2021-09-30 |
2023-08-01 |
美商思進公司 |
用於治療癌症之b7-h4抗體-藥物結合物
|
WO2023060086A1
(en)
|
2021-10-04 |
2023-04-13 |
Takeda Vaccines, Inc. |
Methods for determining norovirus-reactive antibodies
|
WO2023057601A1
(en)
|
2021-10-06 |
2023-04-13 |
Biotalys NV |
Anti-fungal polypeptides
|
US20230190805A1
(en)
|
2021-10-06 |
2023-06-22 |
Immatics Biotechnologies Gmbh |
Methods of identifying metastatic lesions in a patient and treating thereof
|
IL311956A
(en)
|
2021-10-08 |
2024-06-01 |
Chugai Pharmaceutical Co Ltd |
Method for preparing a prefilled syringe formulation
|
AU2022362681A1
(en)
|
2021-10-14 |
2024-04-04 |
F. Hoffmann-La Roche Ag |
New interleukin-7 immunoconjugates
|
WO2023062048A1
(en)
|
2021-10-14 |
2023-04-20 |
F. Hoffmann-La Roche Ag |
Alternative pd1-il7v immunoconjugates for the treatment of cancer
|
WO2023069919A1
(en)
|
2021-10-19 |
2023-04-27 |
Alector Llc |
Anti-cd300lb antibodies and methods of use thereof
|
IL312118A
(en)
|
2021-10-27 |
2024-06-01 |
Imcheck Therapeutics |
Butyrophilin (BTN) A3-activating antibodies for use in infectious disease treatment methods
|
CA3236779A1
(en)
|
2021-10-29 |
2023-05-04 |
Janssen Biotech, Inc. |
Methods of treating crohn's disease with anti-il23 specific antibody
|
TW202325742A
(zh)
|
2021-11-01 |
2023-07-01 |
瑞士商赫孚孟拉羅股份公司 |
使用 HLA-A2/WT1 x CD3 雙特異性抗體及 4-1BB (CD137) 促效劑治療癌症
|
WO2023078900A1
(en)
|
2021-11-03 |
2023-05-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating triple negative breast cancer (tnbc)
|
WO2023081925A1
(en)
|
2021-11-08 |
2023-05-11 |
Immatics Biotechnologies Gmbh |
Adoptive cell therapy combination treatment and compositions thereof
|
US20230272082A1
(en)
|
2021-11-09 |
2023-08-31 |
Sensei Biotherapeutics, Inc. |
Anti-vista antibodies and uses thereof
|
WO2023086807A1
(en)
|
2021-11-10 |
2023-05-19 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
CN118251413A
(zh)
|
2021-11-15 |
2024-06-25 |
詹森生物科技公司 |
用抗il23特异性抗体治疗克罗恩病的方法
|
KR20240102971A
(ko)
|
2021-11-16 |
2024-07-03 |
제넨테크, 인크. |
모수네투주맙을 이용하여 전신 홍반성 루푸스(sle)를 치료하기 위한 방법과 조성물
|
WO2023088889A1
(en)
|
2021-11-16 |
2023-05-25 |
Apogenix Ag |
CD137 ligands
|
WO2023088876A1
(en)
|
2021-11-16 |
2023-05-25 |
Apogenix Ag |
Multi-specific immune modulators
|
KR20240103043A
(ko)
|
2021-11-23 |
2024-07-03 |
얀센 바이오테크 인코포레이티드 |
항-il23 특이적 항체로 궤양성 결장염을 치료하는 방법
|
AU2022395626A1
(en)
|
2021-11-25 |
2024-05-30 |
Veraxa Biotech Gmbh |
Improved antibody-payload conjugates (apcs) prepared by site-specific conjugation utilizing genetic code expansion
|
EP4186529A1
(en)
|
2021-11-25 |
2023-05-31 |
Veraxa Biotech GmbH |
Improved antibody-payload conjugates (apcs) prepared by site-specific conjugation utilizing genetic code expansion
|
WO2023094698A1
(en)
|
2021-11-29 |
2023-06-01 |
Ose Immunotherapeutics |
Specific antagonist anti-sirpg antibodies
|
AR127887A1
(es)
|
2021-12-10 |
2024-03-06 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y plap
|
WO2023110788A1
(en)
|
2021-12-14 |
2023-06-22 |
F. Hoffmann-La Roche Ag |
Treatment of cancer using a hla-a2/mage-a4 x cd3 bispecific antibody and a 4-1bb (cd137) agonist
|
WO2023110937A1
(en)
|
2021-12-14 |
2023-06-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Depletion of nk cells for the treatment of adverse post-ischemic cardiac remodeling
|
CA3241407A1
(en)
|
2021-12-17 |
2023-06-22 |
Dana-Farber Cancer Institute, Inc. |
Platform for antibody discovery
|
WO2023109900A1
(en)
|
2021-12-17 |
2023-06-22 |
Shanghai Henlius Biotech, Inc. |
Anti-ox40 antibodies, multispecific antibodies and methods of use
|
WO2023114544A1
(en)
|
2021-12-17 |
2023-06-22 |
Dana-Farber Cancer Institute, Inc. |
Antibodies and uses thereof
|
AU2022411573A1
(en)
|
2021-12-17 |
2024-06-27 |
Shanghai Henlius Biologics Co., Ltd. |
Anti-ox40 antibodies and methods of use
|
AR128031A1
(es)
|
2021-12-20 |
2024-03-20 |
Hoffmann La Roche |
Anticuerpos agonistas anti-ltbr y anticuerpos biespecíficos que los comprenden
|
WO2023118165A1
(en)
|
2021-12-21 |
2023-06-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
EP4209508A1
(en)
|
2022-01-11 |
2023-07-12 |
Centre national de la recherche scientifique |
Nanobodies for the deneddylating enzyme nedp1
|
TW202340251A
(zh)
|
2022-01-19 |
2023-10-16 |
美商建南德克公司 |
抗notch2抗體及結合物及其使用方法
|
AR128331A1
(es)
|
2022-01-26 |
2024-04-17 |
Genentech Inc |
Inductores químicos de degradación conjugados con anticuerpos y métodos de estos
|
AR128330A1
(es)
|
2022-01-26 |
2024-04-17 |
Genentech Inc |
Inductores químicos de degradación conjugados con anticuerpo y métodos de estos
|
WO2023147399A1
(en)
|
2022-01-27 |
2023-08-03 |
The Rockefeller University |
Broadly neutralizing anti-sars-cov-2 antibodies targeting the n-terminal domain of the spike protein and methods of use thereof
|
WO2023144235A1
(en)
|
2022-01-27 |
2023-08-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for monitoring and treating warburg effect in patients with pi3k-related disorders
|
WO2023144303A1
(en)
|
2022-01-31 |
2023-08-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd38 as a biomarker and biotarget in t-cell lymphomas
|
EP4231017A1
(en)
|
2022-02-17 |
2023-08-23 |
Promise Proteomics |
Detection and quantification of anti-drug antibodies and anti-self antibodies
|
WO2023156634A1
(en)
|
2022-02-17 |
2023-08-24 |
Atb Therapeutics |
Recombinant immunotoxin comprising a ribosome inactivating protein
|
WO2023173026A1
(en)
|
2022-03-10 |
2023-09-14 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
WO2023170247A1
(en)
|
2022-03-11 |
2023-09-14 |
Mablink Bioscience |
Antibody-drug conjugates and their uses
|
WO2023175171A1
(en)
|
2022-03-18 |
2023-09-21 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Bk polyomavirus antibodies and uses thereof
|
WO2023180353A1
(en)
|
2022-03-23 |
2023-09-28 |
F. Hoffmann-La Roche Ag |
Combination treatment of an anti-cd20/anti-cd3 bispecific antibody and chemotherapy
|
WO2023186756A1
(en)
|
2022-03-28 |
2023-10-05 |
F. Hoffmann-La Roche Ag |
Interferon gamma variants and antigen binding molecules comprising these
|
WO2023187707A1
(en)
|
2022-03-30 |
2023-10-05 |
Janssen Biotech, Inc. |
Method of treating mild to moderate psoriasis with il-23 specific antibody
|
WO2023191816A1
(en)
|
2022-04-01 |
2023-10-05 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
EP4257609A1
(en)
|
2022-04-08 |
2023-10-11 |
iOmx Therapeutics AG |
Combination therapies based on pd-1 inhibitors and sik3 inhibitors
|
WO2023198648A1
(en)
|
2022-04-11 |
2023-10-19 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the diagnosis and treatment of t-cell malignancies
|
TW202400243A
(zh)
|
2022-04-12 |
2024-01-01 |
日商衛材R&D企管股份有限公司 |
基於艾日布林的抗體–藥物軛合物及其使用方法
|
TW202408562A
(zh)
|
2022-04-13 |
2024-03-01 |
美商建南德克公司 |
治療性蛋白質之醫藥組成物及使用方法
|
WO2023198727A1
(en)
|
2022-04-13 |
2023-10-19 |
F. Hoffmann-La Roche Ag |
Pharmaceutical compositions of anti-cd20/anti-cd3 bispecific antibodies and methods of use
|
WO2023198851A1
(en)
|
2022-04-14 |
2023-10-19 |
Institut National de la Santé et de la Recherche Médicale |
Methods for controlling the tumor cell killing by light
|
WO2023198874A1
(en)
|
2022-04-15 |
2023-10-19 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the diagnosis and treatment of t cell-lymphomas
|
WO2023212293A1
(en)
|
2022-04-29 |
2023-11-02 |
Broadwing Bio Llc |
Complement factor h related 4-specific antibodies and uses thereof
|
WO2023212294A1
(en)
|
2022-04-29 |
2023-11-02 |
Broadwing Bio Llc |
Angiopoietin-related protein 7-specific antibodies and uses thereof
|
WO2023212298A1
(en)
|
2022-04-29 |
2023-11-02 |
Broadwing Bio Llc |
Bispecific antibodies and methods of treating ocular disease
|
WO2023215737A1
(en)
|
2022-05-03 |
2023-11-09 |
Genentech, Inc. |
Anti-ly6e antibodies, immunoconjugates, and uses thereof
|
WO2023217904A1
(en)
|
2022-05-10 |
2023-11-16 |
Institut National de la Santé et de la Recherche Médicale |
Syncitin-1 fusion proteins and uses thereof for cargo delivery into target cells
|
WO2023219613A1
(en)
|
2022-05-11 |
2023-11-16 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2023218431A1
(en)
|
2022-05-13 |
2023-11-16 |
BioNTech SE |
Rna compositions targeting hiv
|
WO2023223265A1
(en)
|
2022-05-18 |
2023-11-23 |
Janssen Biotech, Inc. |
Method for evaluating and treating psoriatic arthritis with il23 antibody
|
US20230416412A1
(en)
|
2022-05-31 |
2023-12-28 |
Hoffmann-La Roche Inc. |
Prevention or mitigation of t-cell engaging agent-related adverse effects
|
WO2023240058A2
(en)
|
2022-06-07 |
2023-12-14 |
Genentech, Inc. |
Prognostic and therapeutic methods for cancer
|
WO2023237661A1
(en)
|
2022-06-09 |
2023-12-14 |
Institut National de la Santé et de la Recherche Médicale |
Use of endothelin receptor type b agonists for the treatment of aortic valve stenosis
|
WO2024003310A1
(en)
|
2022-06-30 |
2024-01-04 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the diagnosis and treatment of acute lymphoblastic leukemia
|
EP4299124A1
(en)
|
2022-06-30 |
2024-01-03 |
Universite De Montpellier |
Anti-mglur2 nanobodies for use as biomolecule transporter
|
WO2024008274A1
(en)
|
2022-07-04 |
2024-01-11 |
Universiteit Antwerpen |
T regulatory cell modification
|
WO2024008755A1
(en)
|
2022-07-04 |
2024-01-11 |
Vib Vzw |
Blood-cerebrospinal fluid barrier crossing antibodies
|
WO2024008799A1
(en)
|
2022-07-06 |
2024-01-11 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the treatment of proliferative glomerulonephritis
|
WO2024013234A1
(en)
|
2022-07-13 |
2024-01-18 |
Institut National de la Santé et de la Recherche Médicale |
Methods for diagnosis, prognosis, stratification and treating of myocarditis
|
WO2024015897A1
(en)
|
2022-07-13 |
2024-01-18 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
US20240052065A1
(en)
|
2022-07-15 |
2024-02-15 |
Boehringer Ingelheim International Gmbh |
Binding molecules for the treatment of cancer
|
TW202413433A
(zh)
|
2022-07-19 |
2024-04-01 |
美商建南德克公司 |
用抗fcrh5/抗cd3雙特異性抗體進行治療之給藥
|
WO2024018003A1
(en)
|
2022-07-21 |
2024-01-25 |
Institut National de la Santé et de la Recherche Médicale |
Extracellular vesicles functionalized with an erv syncitin and uses thereof for cargo delivery
|
WO2024018426A1
(en)
|
2022-07-22 |
2024-01-25 |
Janssen Biotech, Inc. |
Enhanced transfer of genetic instructions to effector immune cells
|
WO2024020579A1
(en)
|
2022-07-22 |
2024-01-25 |
Bristol-Myers Squibb Company |
Antibodies binding to human pad4 and uses thereof
|
WO2024018046A1
(en)
|
2022-07-22 |
2024-01-25 |
Institut National de la Santé et de la Recherche Médicale |
Garp as a biomarker and biotarget in t-cell malignancies
|
WO2024023246A1
(en)
|
2022-07-28 |
2024-02-01 |
Philogen S.P.A. |
Antibody binding to pd1
|
WO2024026471A1
(en)
|
2022-07-29 |
2024-02-01 |
Alector Llc |
Cd98hc antigen-binding domains and uses therefor
|
WO2024023283A1
(en)
|
2022-07-29 |
2024-02-01 |
Institut National de la Santé et de la Recherche Médicale |
Lrrc33 as a biomarker and biotarget in cutaneous t-cell lymphomas
|
TW202405020A
(zh)
|
2022-07-29 |
2024-02-01 |
美商阿列克特有限責任公司 |
轉鐵蛋白受體抗原結合域及其用途
|
WO2024026447A1
(en)
|
2022-07-29 |
2024-02-01 |
Alector Llc |
Anti-gpnmb antibodies and methods of use thereof
|
WO2024028433A1
(en)
|
2022-08-04 |
2024-02-08 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the treatment of lymphoproliferative disorders
|
WO2024033362A1
(en)
|
2022-08-08 |
2024-02-15 |
Atb Therapeutics |
Humanized antibodies against cd79b
|
WO2024033399A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sigmar1 ligand for the treatment of pancreatic cancer
|
WO2024033400A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sk2 inhibitor for the treatment of pancreatic cancer
|
WO2024040020A1
(en)
|
2022-08-15 |
2024-02-22 |
Absci Corporation |
Quantitative affinity activity specific cell enrichment
|
WO2024038112A1
(en)
|
2022-08-17 |
2024-02-22 |
Institut National de la Santé et de la Recherche Médicale |
Improved anti-albumin nanobodies and their uses
|
WO2024047110A1
(en)
|
2022-08-31 |
2024-03-07 |
Institut National de la Santé et de la Recherche Médicale |
Method to generate more efficient car-t cells
|
WO2024049949A1
(en)
|
2022-09-01 |
2024-03-07 |
Genentech, Inc. |
Therapeutic and diagnostic methods for bladder cancer
|
WO2024052503A1
(en)
|
2022-09-08 |
2024-03-14 |
Institut National de la Santé et de la Recherche Médicale |
Antibodies having specificity to ltbp2 and uses thereof
|
WO2024056668A1
(en)
|
2022-09-12 |
2024-03-21 |
Institut National de la Santé et de la Recherche Médicale |
New anti-itgb8 antibodies and its uses thereof
|
WO2024068705A1
(en)
|
2022-09-29 |
2024-04-04 |
F. Hoffmann-La Roche Ag |
Protease-activated polypeptides
|
WO2024074498A1
(en)
|
2022-10-04 |
2024-04-11 |
Imcheck Therapeutics |
Combination of a btn3a activating antibody, a bcl2 inhibitor and hypomethylating agent for use in treating cancer
|
WO2024077191A1
(en)
|
2022-10-05 |
2024-04-11 |
Flagship Pioneering Innovations V, Inc. |
Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer
|
WO2024074713A1
(en)
|
2022-10-07 |
2024-04-11 |
Institut National de la Santé et de la Recherche Médicale |
Method to generate improving car-t cells
|
WO2024077239A1
(en)
|
2022-10-07 |
2024-04-11 |
Genentech, Inc. |
Methods of treating cancer with anti-c-c motif chemokine receptor 8 (ccr8) antibodies
|
WO2024079015A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and imids
|
WO2024079009A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and proteasome inhibitors
|
WO2024079010A1
(en)
|
2022-10-10 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Combination therapy of a gprc5d tcb and cd38 antibodies
|
WO2024079192A1
(en)
|
2022-10-12 |
2024-04-18 |
Institut National de la Santé et de la Recherche Médicale |
Cd81 as a biomarker and biotarget in t-cell malignancies
|
WO2024083843A1
(en)
|
2022-10-18 |
2024-04-25 |
Confo Therapeutics N.V. |
Amino acid sequences directed against the melanocortin 4 receptor and polypeptides comprising the same for the treatment of mc4r-related diseases and disorders
|
WO2024086796A1
(en)
|
2022-10-20 |
2024-04-25 |
Alector Llc |
Anti-ms4a4a antibodies with amyloid-beta therapies
|
WO2024084034A1
(en)
|
2022-10-21 |
2024-04-25 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of osteoarthritis
|
WO2024091991A1
(en)
|
2022-10-25 |
2024-05-02 |
Genentech, Inc. |
Therapeutic and diagnostic methods for multiple myeloma
|
WO2024091669A1
(en)
|
2022-10-28 |
2024-05-02 |
Ginkgo Bioworks, Inc. |
Chimeric antigen receptors comprising an intracellular domain pair
|
WO2024094741A1
(en)
|
2022-11-03 |
2024-05-10 |
F. Hoffmann-La Roche Ag |
Combination therapy with anti-cd19/anti-cd28 bispecific antibody
|
WO2024102734A1
(en)
|
2022-11-08 |
2024-05-16 |
Genentech, Inc. |
Compositions and methods of treating childhood onset idiopathic nephrotic syndrome
|
WO2024102962A1
(en)
|
2022-11-10 |
2024-05-16 |
Immuvia Inc |
Cytotoxic bispecific antibodies binding to dr5 and muc16 and uses thereof
|
WO2024100170A1
(en)
|
2022-11-11 |
2024-05-16 |
F. Hoffmann-La Roche Ag |
Antibodies binding to hla-a*02/foxp3
|
WO2024110898A1
(en)
|
2022-11-22 |
2024-05-30 |
Janssen Biotech, Inc. |
Method of treating ulcerative colitis with anti-il23 specific antibody
|
WO2024118593A1
(en)
|
2022-11-28 |
2024-06-06 |
Allogene Therapeutics Inc. |
Claudin 18.2 targeting chimeric antigen receptors and binding agents and uses thereof
|
WO2024115349A1
(en)
|
2022-11-29 |
2024-06-06 |
F. Hoffmann-La Roche Ag |
Improved cancer immunotherapy
|
WO2024115935A1
(en)
|
2022-11-29 |
2024-06-06 |
Inserm |
Methods for the treatment of b-cell lymphoma using cd39 inhibitors
|
WO2024129594A1
(en)
|
2022-12-12 |
2024-06-20 |
Genentech, Inc. |
Optimizing polypeptide sialic acid content
|
WO2024129756A1
(en)
|
2022-12-13 |
2024-06-20 |
Seagen Inc. |
Site-specific engineered cysteine antibody drug conjugates
|
WO2024126685A1
(en)
|
2022-12-15 |
2024-06-20 |
Institut National de la Santé et de la Recherche Médicale |
Single-domain antibody targeting von wilebrand factor a3-domain
|
WO2024127366A1
(en)
|
2022-12-16 |
2024-06-20 |
Pheon Therapeutics Ltd |
Antibodies to cub domain-containing protein 1 (cdcp1) and uses thereof
|
WO2024133723A1
(en)
|
2022-12-22 |
2024-06-27 |
Institut National de la Santé et de la Recherche Médicale |
Methods for decreasing therapeutic acquired resistance to chemotherapy and/or radiotherapy
|
WO2024141955A1
(en)
|
2022-12-28 |
2024-07-04 |
BioNTech SE |
Rna compositions targeting hiv
|
WO2024145551A1
(en)
|
2022-12-29 |
2024-07-04 |
Biotalys NV |
Agrochemical compositions
|
WO2024148232A2
(en)
|
2023-01-06 |
2024-07-11 |
Alector Llc |
Anti-il18 binding protein antibodies and methods of use thereof
|
WO2024151687A1
(en)
|
2023-01-09 |
2024-07-18 |
Flagship Pioneering Innovations V, Inc. |
Genetic switches and their use in treating cancer
|
WO2024149821A1
(en)
|
2023-01-13 |
2024-07-18 |
F. Hoffmann-La Roche Ag |
Treatment of cancer using a hla-a2/wt1 x cd3 bispecific antibody and venetoclax/azacitidine
|