USRE30985E
(en)
|
1978-01-01 |
1982-06-29 |
|
Serum-free cell culture media
|
US4419446A
(en)
|
1980-12-31 |
1983-12-06 |
The United States Of America As Represented By The Department Of Health And Human Services |
Recombinant DNA process utilizing a papilloma virus DNA as a vector
|
NZ201705A
(en)
|
1981-08-31 |
1986-03-14 |
Genentech Inc |
Recombinant dna method for production of hepatitis b surface antigen in yeast
|
US4601978A
(en)
|
1982-11-24 |
1986-07-22 |
The Regents Of The University Of California |
Mammalian metallothionein promoter system
|
US4560655A
(en)
|
1982-12-16 |
1985-12-24 |
Immunex Corporation |
Serum-free cell culture medium and process for making same
|
US4657866A
(en)
|
1982-12-21 |
1987-04-14 |
Sudhir Kumar |
Serum-free, synthetic, completely chemically defined tissue culture media
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US4767704A
(en)
|
1983-10-07 |
1988-08-30 |
Columbia University In The City Of New York |
Protein-free culture medium
|
US4965199A
(en)
|
1984-04-20 |
1990-10-23 |
Genentech, Inc. |
Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
|
US4879231A
(en)
|
1984-10-30 |
1989-11-07 |
Phillips Petroleum Company |
Transformation of yeasts of the genus pichia
|
GB8516415D0
(en)
|
1985-06-28 |
1985-07-31 |
Celltech Ltd |
Culture of animal cells
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
US4927762A
(en)
|
1986-04-01 |
1990-05-22 |
Cell Enterprises, Inc. |
Cell culture medium with antioxidant
|
GB8610600D0
(en)
|
1986-04-30 |
1986-06-04 |
Novo Industri As |
Transformation of trichoderma
|
ATE108068T1
(de)
|
1987-09-23 |
1994-07-15 |
Bristol Myers Squibb Co |
Antikörper-heterokonjugate zur töting von hiv- infizierten zellen.
|
EP0435911B1
(en)
|
1988-09-23 |
1996-03-13 |
Cetus Oncology Corporation |
Cell culture medium for enhanced cell growth, culture longevity and product expression
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
DE68913658T3
(de)
|
1988-11-11 |
2005-07-21 |
Stratagene, La Jolla |
Klonierung von Immunglobulin Sequenzen aus den variablen Domänen
|
FR2646437B1
(fr)
|
1989-04-28 |
1991-08-30 |
Transgene Sa |
Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant
|
EP0402226A1
(en)
|
1989-06-06 |
1990-12-12 |
Institut National De La Recherche Agronomique |
Transformation vectors for yeast yarrowia
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
DE69029036T2
(de)
|
1989-06-29 |
1997-05-22 |
Medarex Inc |
Bispezifische reagenzien für die aids-therapie
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
JP3068180B2
(ja)
|
1990-01-12 |
2000-07-24 |
アブジェニックス インコーポレイテッド |
異種抗体の生成
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
ATE158021T1
(de)
|
1990-08-29 |
1997-09-15 |
Genpharm Int |
Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
US5122469A
(en)
|
1990-10-03 |
1992-06-16 |
Genentech, Inc. |
Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
|
DK0564531T3
(da)
|
1990-12-03 |
1998-09-28 |
Genentech Inc |
Berigelsesfremgangsmåde for variantproteiner med ændrede bindingsegenskaber
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
JPH06507398A
(ja)
|
1991-05-14 |
1994-08-25 |
リプリジェン コーポレーション |
Hiv感染治療のための異種複合抗体
|
GB9114948D0
(en)
|
1991-07-11 |
1991-08-28 |
Pfizer Ltd |
Process for preparing sertraline intermediates
|
US7018809B1
(en)
|
1991-09-19 |
2006-03-28 |
Genentech, Inc. |
Expression of functional antibody fragments
|
WO1993006213A1
(en)
|
1991-09-23 |
1993-04-01 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
US5587458A
(en)
|
1991-10-07 |
1996-12-24 |
Aronex Pharmaceuticals, Inc. |
Anti-erbB-2 antibodies, combinations thereof, and therapeutic and diagnostic uses thereof
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
US5667988A
(en)
|
1992-01-27 |
1997-09-16 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
CA2372813A1
(en)
|
1992-02-06 |
1993-08-19 |
L.L. Houston |
Biosynthetic binding protein for cancer marker
|
WO1994004690A1
(en)
|
1992-08-17 |
1994-03-03 |
Genentech, Inc. |
Bispecific immunoadhesins
|
DE69329503T2
(de)
|
1992-11-13 |
2001-05-03 |
Idec Pharma Corp |
Therapeutische Verwendung von chimerischen und markierten Antikörpern, die gegen ein Differenzierung-Antigen gerichtet sind, dessen Expression auf menschliche B Lymphozyt beschränkt ist, für die Behandlung von B-Zell-Lymphoma
|
US5789199A
(en)
|
1994-11-03 |
1998-08-04 |
Genentech, Inc. |
Process for bacterial production of polypeptides
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
US5840523A
(en)
|
1995-03-01 |
1998-11-24 |
Genetech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
US5641870A
(en)
|
1995-04-20 |
1997-06-24 |
Genentech, Inc. |
Low pH hydrophobic interaction chromatography for antibody purification
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
DE69637481T2
(de)
|
1995-04-27 |
2009-04-09 |
Amgen Fremont Inc. |
Aus immunisierten Xenomäusen stammende menschliche Antikörper gegen IL-8
|
AU2466895A
(en)
|
1995-04-28 |
1996-11-18 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
RU2134120C1
(ru)
|
1995-06-26 |
1999-08-10 |
Безруков Михаил Васильевич |
Средство для стабилизации пептидной связи в белковом препарате
|
EP0921855B1
(en)
|
1996-08-30 |
2003-11-19 |
Upfront Chromatography A/S |
Isolation of immunoglobulins
|
KR20080059467A
(ko)
|
1996-12-03 |
2008-06-27 |
아브게닉스, 인크. |
복수의 vh 및 vk 부위를 함유하는 사람 면역글로불린유전자좌를 갖는 형질전환된 포유류 및 이로부터 생성된항체
|
US20080318254A9
(en)
|
1997-03-10 |
2008-12-25 |
The Regents Of The University Of California |
PSCA antibodies and hybridomas producing them
|
US20020173629A1
(en)
|
1997-05-05 |
2002-11-21 |
Aya Jakobovits |
Human monoclonal antibodies to epidermal growth factor receptor
|
US6040498A
(en)
|
1998-08-11 |
2000-03-21 |
North Caroline State University |
Genetically engineered duckweed
|
US6610833B1
(en)
|
1997-11-24 |
2003-08-26 |
The Institute For Human Genetics And Biochemistry |
Monoclonal human natural antibodies
|
WO1999029888A1
(en)
|
1997-12-05 |
1999-06-17 |
The Scripps Research Institute |
Humanization of murine antibody
|
CA2230389A1
(en)
|
1998-04-28 |
1999-10-28 |
Murray N. Waldman |
Formulations containing melatonin to be topically applied for the purpose of protecting the skin from oxidative damage
|
JP2000247903A
(ja)
|
1999-03-01 |
2000-09-12 |
Chugai Pharmaceut Co Ltd |
長期安定化製剤
|
DK1167537T3
(da)
|
1999-03-30 |
2008-11-10 |
Japan Tobacco Inc |
Fremgangsmåde til fremstilling af et monoklonalt antistof
|
US7125978B1
(en)
|
1999-10-04 |
2006-10-24 |
Medicago Inc. |
Promoter for regulating expression of foreign genes
|
WO2001024814A1
(en)
|
1999-10-04 |
2001-04-12 |
Chiron Corporation |
Stabilized liquid polypeptide-containing pharmaceutical compositions
|
PT1222292E
(pt)
|
1999-10-04 |
2005-11-30 |
Medicago Inc |
Metodo para regulacao da transcricao de genes exogenos na presenca de azoto
|
US7163671B2
(en)
|
2000-02-29 |
2007-01-16 |
Chugai Seiyaku Kabushiki Kaisha |
Long-term stabilized formulations
|
US6540791B1
(en)
*
|
2000-03-27 |
2003-04-01 |
The Procter & Gamble Company |
Stable alkaline hair bleaching compositions and method for use thereof
|
WO2002022573A2
(en)
|
2000-09-15 |
2002-03-21 |
The Scripps Research Institute |
Methods and compositions relating to hydrogen peroxide and superoxide production by antibodies
|
US6933123B2
(en)
|
2001-04-05 |
2005-08-23 |
Yao Xiong Hu |
Peptides from the E2, E6, and E7 proteins of human papilloma viruses 16 and 18 for detecting and/or diagnosing cervical and other human papillomavirus associated cancers
|
CA2447114A1
(en)
|
2001-05-16 |
2002-11-21 |
Abgenix, Inc. |
Human antipneumococcal antibodies from non-human animals
|
ATE531390T1
(de)
|
2001-08-23 |
2011-11-15 |
Genmab As |
Interleukin-15-(il-15-)spezifische menschliche antikörper
|
EP1428537B1
(en)
|
2001-08-29 |
2008-11-19 |
Chugai Seiyaku Kabushiki Kaisha |
Stabilized preparations containing antibody
|
US20040116350A1
(en)
|
2001-09-17 |
2004-06-17 |
Paul Wentworth Jr |
Methods and compositions relating to hydrogen peroxide and superoxide production by antibodies
|
EP1539212A4
(en)
|
2002-07-12 |
2007-05-02 |
Medarex Inc |
METHOD AND COMPOSITIONS FOR PREVENTING OXIDATIVE DEGRADATION OF PROTEINS
|
EP1590434A4
(en)
|
2003-01-17 |
2006-11-29 |
Univ New York State Res Found |
ASSOCIATED ANTIGEN, ANTIBODIES, AND DIAGNOSIS AND TREATMENT METHODS WITH CONCENTRATED CANNULA CANCER
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
US7871607B2
(en)
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
JP4999158B2
(ja)
|
2003-05-21 |
2012-08-15 |
メダレツクス・インコーポレーテツド |
炭疽菌(bachillusanthracis)の感染防御抗原に対するヒトモノクローナル抗体
|
MXPA06006868A
(es)
|
2003-12-18 |
2007-03-21 |
Scripps Research Inst |
Incorporacion selectiva de 5-hiroxitriptofano en proteinas de celulas de mamiferos.
|
EP1986674A4
(en)
|
2006-02-13 |
2009-11-11 |
Nektar Therapeutics |
PROTEIN OR PEPTIDE COMPOSITIONS PROTEIN CONTAINING METHIONINE AND METHOD FOR MANUFACTURING AND USING SAME
|
CN101616685B
(zh)
|
2006-03-06 |
2013-07-24 |
阿穆尼克斯运营公司 |
非结构化重组聚合物和其应用
|
WO2007140249A1
(en)
*
|
2006-05-25 |
2007-12-06 |
Biogen Idec Ma Inc. |
Methods of treating stroke
|
JP2007319124A
(ja)
|
2006-06-02 |
2007-12-13 |
Nippon Tablet Kk |
健康食品
|
EP2094247B1
(en)
*
|
2006-10-20 |
2022-06-29 |
Amgen Inc. |
Stable polypeptide formulations
|
CA2675638C
(en)
|
2007-01-16 |
2015-11-24 |
Ipintl, Llc |
Composition comprising serotonin for treating metabolic syndrome
|
CN101074208A
(zh)
|
2007-06-29 |
2007-11-21 |
方炳良 |
吲哚衍生物的制备方法
|
GB0802403D0
(en)
|
2008-02-08 |
2008-03-12 |
Probiox Sa |
Compositions for the treatment of oxidative stress
|
ES2628407T3
(es)
|
2008-04-01 |
2017-08-02 |
Antipodean Pharmaceuticals, Inc. |
Composiciones y procedimientos para el cuidado de la piel
|
RU2414237C2
(ru)
|
2008-04-30 |
2011-03-20 |
Государственное образовательное учреждение высшего профессионального образования "Удмуртский государственный университет" |
Модификация альбумина совиалем как способ повышения его стабильности для производства фармацевтического биопрепарата альбумина в комплексе с гентамицином или стимаденом
|
JP2012500263A
(ja)
|
2008-08-21 |
2012-01-05 |
アルヴィン ファーマシューティカルズ インコーポレーティッド |
タンパク質の経口投与のための製剤
|
MX2011002372A
(es)
|
2008-09-10 |
2011-04-04 |
Genentech Inc |
Composiciones y metodos para la prevencion de la degradacion oxidativa de proteinas.
|
EP2331090B1
(en)
|
2008-09-19 |
2018-01-03 |
Pfizer Inc. |
Stable liquid antibody formulation
|
SG186783A1
(en)
|
2010-06-24 |
2013-02-28 |
Genentech Inc |
Compositions and methods containing alkylgycosides for stabilizing protein- containing formulations
|
RU2447448C1
(ru)
|
2010-08-30 |
2012-04-10 |
Государственное образовательное учреждение высшего профессионального образования "Оренбургский государственный университет" |
Способ стабилизации антител в водных растворах
|
KR101309789B1
(ko)
*
|
2011-01-26 |
2013-09-23 |
(주)프로테옴텍 |
티로신 산화물이 결합된 바이오 물질을 포함하는 단백질 검출용 조성물
|
EP2717698A4
(en)
|
2011-06-09 |
2015-01-07 |
Requis Pharmaceuticals Inc |
ANTIHISTAMINES COMBINED WITH FOOD SUPPLEMENTS TO IMPROVE HEALTH
|
JP2014522827A
(ja)
|
2011-06-28 |
2014-09-08 |
ロイコケア・アクチェンゲゼルシャフト |
(ポリ)ペプチドのアンフォールディングを防止し、および/または(ポリ)ペプチドの(リ)フォールディングを誘導するための方法
|
US20140314778A1
(en)
|
2013-03-13 |
2014-10-23 |
Genentech, Inc. |
Formulations with reduced oxidation
|
JP6389236B2
(ja)
|
2013-03-13 |
2018-09-12 |
ジェネンテック, インコーポレイテッド |
酸化還元製剤
|
US10653779B2
(en)
|
2013-03-13 |
2020-05-19 |
Genentech, Inc. |
Formulations with reduced oxidation
|