DK1167537T3 - Fremgangsmåde til fremstilling af et monoklonalt antistof - Google Patents

Fremgangsmåde til fremstilling af et monoklonalt antistof

Info

Publication number
DK1167537T3
DK1167537T3 DK00912975T DK00912975T DK1167537T3 DK 1167537 T3 DK1167537 T3 DK 1167537T3 DK 00912975 T DK00912975 T DK 00912975T DK 00912975 T DK00912975 T DK 00912975T DK 1167537 T3 DK1167537 T3 DK 1167537T3
Authority
DK
Denmark
Prior art keywords
monoclonal antibody
producing
hybridoma
immortalized
cell
Prior art date
Application number
DK00912975T
Other languages
English (en)
Inventor
Chihiro Kusunoki
Atsushi Fukushima
Original Assignee
Japan Tobacco Inc
Amgen Fremont Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc, Amgen Fremont Inc filed Critical Japan Tobacco Inc
Application granted granted Critical
Publication of DK1167537T3 publication Critical patent/DK1167537T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/10Plasmid DNA
    • C12N2800/108Plasmid DNA episomal vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/42Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK00912975T 1999-03-30 2000-03-30 Fremgangsmåde til fremstilling af et monoklonalt antistof DK1167537T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8792999 1999-03-30
PCT/JP2000/002022 WO2000058499A1 (fr) 1999-03-30 2000-03-30 Procede pour la production d'anticorps monoclonal

Publications (1)

Publication Number Publication Date
DK1167537T3 true DK1167537T3 (da) 2008-11-10

Family

ID=13928616

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00912975T DK1167537T3 (da) 1999-03-30 2000-03-30 Fremgangsmåde til fremstilling af et monoklonalt antistof

Country Status (8)

Country Link
US (1) US8236530B2 (da)
EP (1) EP1167537B1 (da)
AT (1) ATE402267T1 (da)
AU (1) AU754808B2 (da)
CA (1) CA2368734C (da)
DE (1) DE60039596D1 (da)
DK (1) DK1167537T3 (da)
WO (1) WO2000058499A1 (da)

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Also Published As

Publication number Publication date
US20060059575A1 (en) 2006-03-16
CA2368734C (en) 2005-08-23
DE60039596D1 (de) 2008-09-04
AU3456300A (en) 2000-10-16
CA2368734A1 (en) 2000-10-05
EP1167537B1 (en) 2008-07-23
US8236530B2 (en) 2012-08-07
EP1167537A1 (en) 2002-01-02
ATE402267T1 (de) 2008-08-15
AU754808B2 (en) 2002-11-28
WO2000058499A1 (fr) 2000-10-05
EP1167537A4 (en) 2005-05-04

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