DK0419858T3 - Hunde-muse-heterohybridom og genfragment, som koder for den konstante region af hundeimmunglobuliner - Google Patents

Hunde-muse-heterohybridom og genfragment, som koder for den konstante region af hundeimmunglobuliner

Info

Publication number
DK0419858T3
DK0419858T3 DK90116258.6T DK90116258T DK0419858T3 DK 0419858 T3 DK0419858 T3 DK 0419858T3 DK 90116258 T DK90116258 T DK 90116258T DK 0419858 T3 DK0419858 T3 DK 0419858T3
Authority
DK
Denmark
Prior art keywords
gene fragment
canine
constant region
amino acid
acid sequence
Prior art date
Application number
DK90116258.6T
Other languages
English (en)
Inventor
Sachio Tokiyoshi
Hiroaki Maeda
Yasuyuki Eda
Kazuhiko Kimachi
Yoichi Ono
Original Assignee
Chemo Sero Therapeut Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1219889A external-priority patent/JP2811089B2/ja
Priority claimed from JP25542589A external-priority patent/JP2811096B2/ja
Priority claimed from JP2150673A external-priority patent/JP2837240B2/ja
Application filed by Chemo Sero Therapeut Res Inst filed Critical Chemo Sero Therapeut Res Inst
Application granted granted Critical
Publication of DK0419858T3 publication Critical patent/DK0419858T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK90116258.6T 1989-08-25 1990-08-24 Hunde-muse-heterohybridom og genfragment, som koder for den konstante region af hundeimmunglobuliner DK0419858T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1219889A JP2811089B2 (ja) 1989-08-25 1989-08-25 イヌ×マウスヘテロハイブリドーマおよびイヌ免疫グロブリンλ鎖の定常領域をコードする遺伝子断片
JP25542589A JP2811096B2 (ja) 1989-09-30 1989-09-30 イヌ免疫グロブリンκ鎖の定常領域をコードする遺伝子断片およびマウス×イヌキメラ抗体
JP2150673A JP2837240B2 (ja) 1990-06-07 1990-06-07 イヌ免疫グロブリンγ鎖の定常領域をコードする遺伝子断片およびマウス×イヌキメラ抗体

Publications (1)

Publication Number Publication Date
DK0419858T3 true DK0419858T3 (da) 1995-07-10

Family

ID=27319982

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90116258.6T DK0419858T3 (da) 1989-08-25 1990-08-24 Hunde-muse-heterohybridom og genfragment, som koder for den konstante region af hundeimmunglobuliner

Country Status (8)

Country Link
US (2) US5593861A (da)
EP (1) EP0419858B1 (da)
AT (1) ATE122716T1 (da)
AU (1) AU640397B2 (da)
CA (1) CA2023894C (da)
DE (1) DE69019447T2 (da)
DK (1) DK0419858T3 (da)
ES (1) ES2075099T3 (da)

Families Citing this family (28)

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US7393529B2 (en) 1998-04-09 2008-07-01 Idexx Laboratories, Inc. Methods and compositions for inhibiting binding of IgE to a high affinity receptor
US6537781B1 (en) 1999-08-10 2003-03-25 Idexx Laboratories, Inc. Methods and compositions concerning canine interleukin 5
EP1268794A2 (en) 2000-04-07 2003-01-02 Heska Corporation Compositions and methods related to canine igg and canine il-13 receptors
AU2002359851A1 (en) * 2001-12-21 2003-07-30 Idexx Laboratories, Inc. Canine immunoglobulin variable domains, caninized antibodies, and methods for making and using them
US20030163618A1 (en) * 2002-02-27 2003-08-28 Vishal Anand Shared queue for multiple input-streams
AU2009270182B2 (en) * 2008-07-10 2015-01-22 Toray Industries, Inc. Immunity-inducing agent and method for detection of cancer
US10611835B2 (en) 2008-07-10 2020-04-07 Toray Industries, Inc. Pharmaceutical composition for treatment and prevention of cancer
US8337842B2 (en) * 2008-09-04 2012-12-25 Vet Therapeutics, Inc. Monoclonal antibodies
US8313915B2 (en) * 2009-01-21 2012-11-20 Gundersen Lutheran Medical Foundation, Inc. Early detection of canine lyme disease by specific peptides and antibodies
US8569460B2 (en) 2009-03-25 2013-10-29 Vet Therapeutics, Inc. Antibody constant domain regions and uses thereof
JP2012521784A (ja) * 2009-03-30 2012-09-20 ベーリンガー・インゲルハイム・インテルナツィオナール・ゲーエムバーハー イヌＦｃ部分を含む融合タンパク質
WO2010117448A2 (en) * 2009-04-05 2010-10-14 Provenance Biopharmaceuticals Corp. Chimeric immunocytokines and methods of use thereof
EP2496604B1 (en) 2009-11-06 2017-08-23 IDEXX Laboratories, Inc. Canine anti-cd20 antibodies
WO2011109662A1 (en) 2010-03-04 2011-09-09 Vet Therapeutics, Inc. Monoclonal antibodies directed to cd52
US9616120B2 (en) 2010-03-04 2017-04-11 Vet Therapeutics, Inc. Monoclonal antibodies directed to CD20
ES2665954T3 (es) 2010-08-19 2018-04-30 Zoetis Belgium S.A. Anticuerpos anti-NGF y su uso
GB201114858D0 (en) 2011-08-29 2011-10-12 Nvip Pty Ltd Anti-nerve growth factor antibodies and methods of using the same
EP3626739A1 (en) 2011-06-24 2020-03-25 Stephen D. Gillies Light chain immunoglobulin fusion proteins and methods of use thereof
CA2847020A1 (en) 2011-08-30 2013-03-07 Nvip Pty Ltd Caninised tumour necrosis factor antibodies and methods of using the same
JP6316195B2 (ja) 2011-10-26 2018-04-25 エランコ ティーアゲズンタイト アーゲー モノクローナル抗体および使用の方法
CN104159916A (zh) 2012-02-22 2014-11-19 Nvip私人有限公司 肿瘤坏死因子受体融合蛋白及其使用方法
WO2013184871A1 (en) 2012-06-06 2013-12-12 Zoetis Llc Caninized anti-ngf antibodies and methods thereof
CN108699141B (zh) * 2016-01-06 2022-06-17 定制药品研究株式会社 高亲和性抗vegf抗体
JP6925981B2 (ja) 2016-01-06 2021-08-25 株式会社オーダーメードメディカルリサーチ Ｖｅｇｆとｎｒｐ１との結合を阻害する抗体
KR102569068B1 (ko) * 2016-08-15 2023-08-21 국립대학법인 홋가이도 다이가쿠 항pd-l1 항체
GB2561352B (en) * 2017-04-10 2023-01-18 Genome Res Ltd Animal models and therapeutic molecules
BR112020017701A2 (pt) 2018-03-12 2020-12-29 Zoetis Services Llc Anticorpos anti-ngf e métodos dos mesmos
GB2578867A (en) * 2018-10-09 2020-06-03 Genome Res Ltd Animal models and therapeutic molecules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4842999A (en) * 1986-08-11 1989-06-27 Adi Diagnostics Inc. Canine heartworm vaccine and diagnostic test
CA1340898C (en) * 1987-04-30 2000-02-15 The Wistar Institute Monoclonal antibodies against lymphoma-associated antigens, hybrid cell lines producing these antibodies, and use therefore

Also Published As

Publication number Publication date
CA2023894C (en) 2001-09-18
ATE122716T1 (de) 1995-06-15
EP0419858B1 (en) 1995-05-17
AU6120490A (en) 1991-02-28
AU640397B2 (en) 1993-08-26
DE69019447T2 (de) 1995-10-26
ES2075099T3 (es) 1995-10-01
US5593861A (en) 1997-01-14
CA2023894A1 (en) 1991-02-26
EP0419858A1 (en) 1991-04-03
DE69019447D1 (de) 1995-06-22
US5852183A (en) 1998-12-22

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