ATE122716T1 - Hund-maus-heterohybridoma und für die konstante region von hunde-immunglobulinen kodierendes genfragment. - Google Patents

Hund-maus-heterohybridoma und für die konstante region von hunde-immunglobulinen kodierendes genfragment.

Info

Publication number
ATE122716T1
ATE122716T1 AT90116258T AT90116258T ATE122716T1 AT E122716 T1 ATE122716 T1 AT E122716T1 AT 90116258 T AT90116258 T AT 90116258T AT 90116258 T AT90116258 T AT 90116258T AT E122716 T1 ATE122716 T1 AT E122716T1
Authority
AT
Austria
Prior art keywords
gene fragment
constant region
mouse
amino acid
acid sequence
Prior art date
Application number
AT90116258T
Other languages
English (en)
Inventor
Hiroaki Maeda
Yasuyuki Eda
Kazuhiko Kimachi
Yoichi Ono
Sachio Tokiyoshi
Original Assignee
Chemo Sero Therapeut Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1219889A external-priority patent/JP2811089B2/ja
Priority claimed from JP25542589A external-priority patent/JP2811096B2/ja
Priority claimed from JP2150673A external-priority patent/JP2837240B2/ja
Application filed by Chemo Sero Therapeut Res Inst filed Critical Chemo Sero Therapeut Res Inst
Application granted granted Critical
Publication of ATE122716T1 publication Critical patent/ATE122716T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT90116258T 1989-08-25 1990-08-24 Hund-maus-heterohybridoma und für die konstante region von hunde-immunglobulinen kodierendes genfragment. ATE122716T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1219889A JP2811089B2 (ja) 1989-08-25 1989-08-25 イヌ×マウスヘテロハイブリドーマおよびイヌ免疫グロブリンλ鎖の定常領域をコードする遺伝子断片
JP25542589A JP2811096B2 (ja) 1989-09-30 1989-09-30 イヌ免疫グロブリンκ鎖の定常領域をコードする遺伝子断片およびマウス×イヌキメラ抗体
JP2150673A JP2837240B2 (ja) 1990-06-07 1990-06-07 イヌ免疫グロブリンγ鎖の定常領域をコードする遺伝子断片およびマウス×イヌキメラ抗体

Publications (1)

Publication Number Publication Date
ATE122716T1 true ATE122716T1 (de) 1995-06-15

Family

ID=27319982

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90116258T ATE122716T1 (de) 1989-08-25 1990-08-24 Hund-maus-heterohybridoma und für die konstante region von hunde-immunglobulinen kodierendes genfragment.

Country Status (8)

Country Link
US (2) US5593861A (de)
EP (1) EP0419858B1 (de)
AT (1) ATE122716T1 (de)
AU (1) AU640397B2 (de)
CA (1) CA2023894C (de)
DE (1) DE69019447T2 (de)
DK (1) DK0419858T3 (de)
ES (1) ES2075099T3 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7393529B2 (en) 1998-04-09 2008-07-01 Idexx Laboratories, Inc. Methods and compositions for inhibiting binding of IgE to a high affinity receptor
US6537781B1 (en) 1999-08-10 2003-03-25 Idexx Laboratories, Inc. Methods and compositions concerning canine interleukin 5
WO2001077332A2 (en) * 2000-04-07 2001-10-18 Heska Corporation Compositions and methods related to canine igg and canine il-13 receptors
US7261890B2 (en) * 2001-12-21 2007-08-28 Idexx Laboratories, Inc. Methods for using canine immunoglobulin variable domains and caninized antibodies
US20030163618A1 (en) * 2002-02-27 2003-08-28 Vishal Anand Shared queue for multiple input-streams
BRPI0910513B8 (pt) * 2008-07-10 2021-05-25 Toray Industries uso de pelo menos um polipeptídeo, método para a detecção de câncer de mama e leucemia in vitro, e reagente para a detecção de câncer de mama e leucemia
AU2009270181B2 (en) 2008-07-10 2014-05-29 Toray Industries, Inc. Pharmaceutical composition for treatment and prevention of cancer
WO2010027488A2 (en) * 2008-09-04 2010-03-11 Vet Therapeutics, Inc. Monoclonal antibodies
US8313915B2 (en) * 2009-01-21 2012-11-20 Gundersen Lutheran Medical Foundation, Inc. Early detection of canine lyme disease by specific peptides and antibodies
US8569460B2 (en) 2009-03-25 2013-10-29 Vet Therapeutics, Inc. Antibody constant domain regions and uses thereof
EP2413969A4 (de) * 2009-03-30 2012-09-05 Boehringer Ingelheim Int Fusionsproteine mit hunde-fc-elementen
WO2010117448A2 (en) * 2009-04-05 2010-10-14 Provenance Biopharmaceuticals Corp. Chimeric immunocytokines and methods of use thereof
WO2011057188A1 (en) 2009-11-06 2011-05-12 Idexx Laboratories, Inc. Canine anti-cd20 antibodies
US9616120B2 (en) 2010-03-04 2017-04-11 Vet Therapeutics, Inc. Monoclonal antibodies directed to CD20
JP2013520999A (ja) 2010-03-04 2013-06-10 ベット・セラピューティクス・インコーポレイテッド Ｃｄ５２に対するモノクローナル抗体
AU2011291462A1 (en) 2010-08-19 2013-03-14 Zoetis Belgium S.A. Anti-NGF antibodies and their use
GB201114858D0 (en) 2011-08-29 2011-10-12 Nvip Pty Ltd Anti-nerve growth factor antibodies and methods of using the same
WO2012178137A1 (en) 2011-06-24 2012-12-27 Gillies Stephen D Light chain immunoglobulin fusion proteins and methods of use thereof
CN103958545A (zh) 2011-08-30 2014-07-30 Nvip私人有限公司 犬源化肿瘤坏死因子抗体及其使用方法
EP2771694A4 (de) 2011-10-26 2015-08-05 Novartis Tiergesundheit Ag Monoklonale antikörper und verfahren zu ihrer verwendung
NZ629309A (en) 2012-02-22 2016-03-31 Nvip Pty Ltd Tumour necrosis factor receptor fusion proteins and methods of using the same
US9617334B2 (en) 2012-06-06 2017-04-11 Zoetis Services Llc Caninized anti-NGF antibodies and methods thereof
JP6910963B2 (ja) * 2016-01-06 2021-07-28 株式会社オーダーメードメディカルリサーチ 高親和性抗ｖｅｇｆ抗体
KR102293753B1 (ko) 2016-01-06 2021-08-24 오더-메이드 메디컬 리서치 인코포레이티드 Vegf 와 nrp1 의 결합을 저해하는 항체
RU2744862C2 (ru) * 2016-08-15 2021-03-16 Нэшнл Юниверсити Корпорейшн Хоккайдо Юниверсити Антитело против pd-l1
GB2561352B (en) * 2017-04-10 2023-01-18 Genome Res Ltd Animal models and therapeutic molecules
BR112020017701A2 (pt) 2018-03-12 2020-12-29 Zoetis Services Llc Anticorpos anti-ngf e métodos dos mesmos
GB2578867A (en) * 2018-10-09 2020-06-03 Genome Res Ltd Animal models and therapeutic molecules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4842999A (en) * 1986-08-11 1989-06-27 Adi Diagnostics Inc. Canine heartworm vaccine and diagnostic test
CA1340898C (en) * 1987-04-30 2000-02-15 The Wistar Institute Monoclonal antibodies against lymphoma-associated antigens, hybrid cell lines producing these antibodies, and use therefore

Also Published As

Publication number Publication date
ES2075099T3 (es) 1995-10-01
CA2023894A1 (en) 1991-02-26
US5593861A (en) 1997-01-14
DE69019447T2 (de) 1995-10-26
AU640397B2 (en) 1993-08-26
AU6120490A (en) 1991-02-28
EP0419858A1 (de) 1991-04-03
DK0419858T3 (da) 1995-07-10
CA2023894C (en) 2001-09-18
EP0419858B1 (de) 1995-05-17
DE69019447D1 (de) 1995-06-22
US5852183A (en) 1998-12-22

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee