MX2009009283A - Anticuerpos anti-interleuquina -23r de ingenieria. - Google Patents

Anticuerpos anti-interleuquina -23r de ingenieria.

Info

Publication number
MX2009009283A
MX2009009283A MX2009009283A MX2009009283A MX2009009283A MX 2009009283 A MX2009009283 A MX 2009009283A MX 2009009283 A MX2009009283 A MX 2009009283A MX 2009009283 A MX2009009283 A MX 2009009283A MX 2009009283 A MX2009009283 A MX 2009009283A
Authority
MX
Mexico
Prior art keywords
antibodies
engineered anti
engineered
autoimmune
inflammatory
Prior art date
Application number
MX2009009283A
Other languages
English (en)
Inventor
Leonard G Presta
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of MX2009009283A publication Critical patent/MX2009009283A/es

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Abstract

Se proveen anticuerpos para el IL-23R humano así como usos de los mismos, por ejemplo en el tratamiento de trastornos inflamatorios, autoinmunes y proliferativos.
MX2009009283A 2007-02-28 2008-02-26 Anticuerpos anti-interleuquina -23r de ingenieria. MX2009009283A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89210407P 2007-02-28 2007-02-28
US94518307P 2007-06-20 2007-06-20
PCT/US2008/002534 WO2008106134A2 (en) 2007-02-28 2008-02-26 Engineered anti-il-23r antibodies

Publications (1)

Publication Number Publication Date
MX2009009283A true MX2009009283A (es) 2009-11-18

Family

ID=39529694

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009009283A MX2009009283A (es) 2007-02-28 2008-02-26 Anticuerpos anti-interleuquina -23r de ingenieria.

Country Status (14)

Country Link
US (4) US8119133B2 (es)
EP (2) EP2395025A1 (es)
JP (3) JP5238723B2 (es)
KR (1) KR20100014568A (es)
CN (1) CN101675076B (es)
AR (1) AR065496A1 (es)
AU (1) AU2008219684B2 (es)
BR (1) BRPI0807991A2 (es)
CA (1) CA2679381A1 (es)
IL (1) IL200581A0 (es)
MX (1) MX2009009283A (es)
NZ (1) NZ579251A (es)
WO (1) WO2008106134A2 (es)
ZA (1) ZA200905964B (es)

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WO2010027767A1 (en) * 2008-08-27 2010-03-11 Schering Corporation Engineered anti-il-23r antibodies
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TW201249867A (en) * 2011-04-01 2012-12-16 Astellas Pharma Inc Novel anti-human il-23 receptor antibody
USRE49026E1 (en) 2011-06-14 2022-04-12 Medical Diagnostic Laboratories, Llc Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof
US8946150B2 (en) 2011-06-14 2015-02-03 Medical Diagnostic Laboratories, LLC. Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof
PT2821416T (pt) 2012-02-28 2018-12-14 Astellas Pharma Inc Anticorpo de recetor il-23 anti- humano inovador
KR20160007604A (ko) * 2013-05-10 2016-01-20 누맙 아게 이중특이성 작제물 및 다양한 질병의 치료에서의 이의 용도
WO2015011658A1 (en) * 2013-07-23 2015-01-29 Biocon Limited Use of a cd6 binding partner and method based thereon
EP4198059A1 (en) 2014-05-27 2023-06-21 The University of Queensland Modulation of cellular stress
WO2016102641A1 (en) * 2014-12-24 2016-06-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of acute exacerbations of chronic obstructive pulmonary disease
CZ307849B6 (cs) * 2016-06-03 2019-06-26 Biotechnologický ústav AV ČR, v. v. i. Polypeptidy pro léčbu autoimunitních chorob založenou na blokaci podjednotky p19 lidského cytokinu IL-23
EP3529274B1 (en) 2016-10-21 2024-04-17 Biocon Limited A monoclonal antibody and a method of use for the treatment of lupus
CA3058952A1 (en) * 2017-05-02 2018-11-08 Dana-Farber Cancer Institute, Inc. Il-23r antagonists to reprogram intratumoral t regulatory cells into effector cells
MX2023001490A (es) * 2020-08-05 2023-04-27 Synthekine Inc Moleculas de union a il27r\03b1 y metodos de uso.
CA3222871A1 (en) * 2021-06-25 2022-12-29 Sangamo Therapeutics, Inc. Antigen binders specific for il-23r and uses thereof

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KR20100014568A (ko) 2010-02-10
US8309085B2 (en) 2012-11-13
ZA200905964B (en) 2010-05-26
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US8119133B2 (en) 2012-02-21
US20130064817A1 (en) 2013-03-14
CN101675076A (zh) 2010-03-17
CA2679381A1 (en) 2008-09-04
US20100166767A1 (en) 2010-07-01
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EP2057194A2 (en) 2009-05-13
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US20140170154A1 (en) 2014-06-19

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