MY162511A - Engineered anti-tslp antibody - Google Patents

Engineered anti-tslp antibody

Info

Publication number
MY162511A
MY162511A MYPI2012001964A MYPI2012001964A MY162511A MY 162511 A MY162511 A MY 162511A MY PI2012001964 A MYPI2012001964 A MY PI2012001964A MY PI2012001964 A MYPI2012001964 A MY PI2012001964A MY 162511 A MY162511 A MY 162511A
Authority
MY
Malaysia
Prior art keywords
engineered anti
tslp antibody
tslp
antibody
treatment
Prior art date
Application number
MYPI2012001964A
Inventor
Leonard G Presta
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of MY162511A publication Critical patent/MY162511A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Abstract

THE INVENTION RELATES TO BINDING COMPOUNDS THAT SPECIFICALLY BIND TO HUMAN TSLP, AS WELL AS USES THEREOF, E.G., IN THE TREATMENT OF INFLAMMATORY DISORDERS AND ALLERGIC INFLAMMATORY RESPONSE.
MYPI2012001964A 2009-11-04 2010-11-02 Engineered anti-tslp antibody MY162511A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25805109P 2009-11-04 2009-11-04
US29700810P 2010-01-21 2010-01-21

Publications (1)

Publication Number Publication Date
MY162511A true MY162511A (en) 2017-06-15

Family

ID=43970291

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2012001964A MY162511A (en) 2009-11-04 2010-11-02 Engineered anti-tslp antibody

Country Status (19)

Country Link
US (2) US8637019B2 (en)
EP (2) EP2496707B1 (en)
JP (2) JP6077856B2 (en)
KR (1) KR101898739B1 (en)
CN (1) CN102782149B (en)
AR (1) AR078899A1 (en)
AU (1) AU2010315304B2 (en)
BR (1) BR112012010707B1 (en)
CA (1) CA2779384C (en)
CL (1) CL2012001179A1 (en)
CO (1) CO6531489A2 (en)
EC (1) ECSP12011879A (en)
ES (1) ES2784123T3 (en)
IL (1) IL219204A0 (en)
MX (1) MX2012005180A (en)
MY (1) MY162511A (en)
NZ (1) NZ599761A (en)
PE (1) PE20121646A1 (en)
WO (1) WO2011056772A1 (en)

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NZ599761A (en) * 2009-11-04 2014-04-30 Merck Sharp & Dohme Engineered anti-tslp antibody
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AR090915A1 (en) * 2012-05-04 2014-12-17 Intervet Int Bv PROTEIN OF FUSION OF PROTEIN LINFOPOYETINA ESTROMAL TIMICA CANINA WITH THE REGION FC OF IGG
WO2014031718A1 (en) 2012-08-23 2014-02-27 Merck Sharp & Dohme Corp. Stable formulations of antibodies to tslp
EP3789022A1 (en) 2012-12-27 2021-03-10 Massachusetts Eye & Ear Infirmary Treatment of rhinosinusitis with p-glycoprotein inhibitors
WO2015187519A1 (en) * 2014-06-06 2015-12-10 Merck Sharp & Dohme Corp. Tslp assay
US10000561B2 (en) 2015-09-09 2018-06-19 Novartis Ag Thymic stromal lymphopoietin (TSLP)-binding molecules and methods of using the molecules
CA2996635A1 (en) * 2015-09-09 2017-03-16 Novartis Ag Thymic stromal lymphopoietin (tslp)-binding molecules and methods of using the molecules
JP6855469B2 (en) 2015-10-16 2021-04-07 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． Steps for preparing a prescription for gastrointestinal targeted therapy
WO2017123933A1 (en) 2016-01-15 2017-07-20 Massachusetts Eye And Ear Infirmary Secreted p-glycoprotein is a non-invasive biomarker of chronic rhinosinusitis
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US11407830B2 (en) * 2017-01-09 2022-08-09 Tesaro, Inc. Methods of treating cancer with anti-PD-1 antibodies
JOP20190243A1 (en) 2017-04-12 2019-10-13 Medimmune Llc Treatment of asthma with anti-tslp antibody
JOP20190260A1 (en) 2017-05-02 2019-10-31 Merck Sharp & Dohme Stable formulations of programmed death receptor 1 (pd-1) antibodies and methods of use thereof
MX2019013072A (en) 2017-05-02 2019-12-16 Merck Sharp & Dohme Formulations of anti-lag3 antibodies and co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies.
EP3981788A4 (en) 2019-06-04 2023-03-22 Jiangsu Hengrui Medicine Co., Ltd. Antibody capable of binding to thymic stromal lymphopoietin and use thereof
KR20220113673A (en) * 2019-12-13 2022-08-16 쓰촨 케룬-바이오테크 바이오파마수티컬 컴퍼니 리미티드 Anti-TSLP Antibodies and Their Uses
TW202140550A (en) 2020-01-29 2021-11-01 瑞士商諾華公司 Methods of treating an inflammatory or obstructive airway disease using anti-tslp antibody
US20230073888A1 (en) 2020-02-13 2023-03-09 Amgen Inc. Treatment of atopic dermatitis with anti-tslp antibody
IL295042A (en) 2020-02-13 2022-09-01 Amgen Inc Formulations of human anti-tslp antibodies and methods of treating inflammatory disease
IL295511A (en) 2020-02-18 2022-10-01 Amgen Inc Formulations of human anti-tslp antibodies and methods of using the same
CN113501878B (en) * 2021-02-03 2022-12-02 北京智仁美博生物科技有限公司 Antibodies against human TSLP and uses thereof
CN113069543B (en) * 2021-06-07 2021-08-06 迈威(上海)生物科技股份有限公司 Liquid composition comprising monoclonal antibodies against thymic stromal lymphopoietin

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Also Published As

Publication number Publication date
CA2779384C (en) 2018-02-27
EP2496707B1 (en) 2020-02-26
JP2013509862A (en) 2013-03-21
JP2016175894A (en) 2016-10-06
US8637019B2 (en) 2014-01-28
AR078899A1 (en) 2011-12-14
CA2779384A1 (en) 2011-05-12
PE20121646A1 (en) 2012-12-02
CN102782149B (en) 2014-11-12
MX2012005180A (en) 2012-06-08
ECSP12011879A (en) 2012-07-31
RU2012122816A (en) 2013-12-10
US20140141012A1 (en) 2014-05-22
NZ599761A (en) 2014-04-30
KR101898739B1 (en) 2018-09-13
CO6531489A2 (en) 2012-09-28
CN102782149A (en) 2012-11-14
BR112012010707A2 (en) 2020-08-25
US20120219565A1 (en) 2012-08-30
IL219204A0 (en) 2012-06-28
AU2010315304A1 (en) 2012-05-17
EP3594356A1 (en) 2020-01-15
KR20120102623A (en) 2012-09-18
WO2011056772A1 (en) 2011-05-12
ES2784123T3 (en) 2020-09-22
CL2012001179A1 (en) 2012-10-19
JP6077856B2 (en) 2017-02-08
BR112012010707B1 (en) 2022-08-30
EP2496707A1 (en) 2012-09-12
AU2010315304B2 (en) 2014-03-27
EP2496707A4 (en) 2013-06-26

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