MX2010008688A - Anticuerpos anti-receptor de linfopoyetina estromal timica procesados por ingenieria. - Google Patents
Anticuerpos anti-receptor de linfopoyetina estromal timica procesados por ingenieria.Info
- Publication number
- MX2010008688A MX2010008688A MX2010008688A MX2010008688A MX2010008688A MX 2010008688 A MX2010008688 A MX 2010008688A MX 2010008688 A MX2010008688 A MX 2010008688A MX 2010008688 A MX2010008688 A MX 2010008688A MX 2010008688 A MX2010008688 A MX 2010008688A
- Authority
- MX
- Mexico
- Prior art keywords
- engineered anti
- tslpr antibodies
- tslpr
- antibodies
- engineered
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Abstract
La invención se refiere a compuestos de unión que específicamente se unen al TSLPR humano, así como también a usos de los mismos, por ejemplo, en el tratamiento de trastornos inflamatorios.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2683308P | 2008-02-07 | 2008-02-07 | |
US4203008P | 2008-04-03 | 2008-04-03 | |
PCT/US2009/033383 WO2009100324A1 (en) | 2008-02-07 | 2009-02-06 | Engineered anti-tslpr antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010008688A true MX2010008688A (es) | 2010-08-30 |
Family
ID=40622088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010008688A MX2010008688A (es) | 2008-02-07 | 2009-02-06 | Anticuerpos anti-receptor de linfopoyetina estromal timica procesados por ingenieria. |
Country Status (8)
Country | Link |
---|---|
US (1) | US8475793B2 (es) |
EP (1) | EP2250199B1 (es) |
JP (2) | JP2011511638A (es) |
CN (1) | CN101986784A (es) |
AR (1) | AR070346A1 (es) |
CA (1) | CA2713935C (es) |
MX (1) | MX2010008688A (es) |
WO (1) | WO2009100324A1 (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008155365A1 (en) | 2007-06-20 | 2008-12-24 | Irm Llc | Methods and compositions for treating allergic diseases |
JOP20080381B1 (ar) | 2007-08-23 | 2023-03-28 | Amgen Inc | بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9) |
EP2320731A4 (en) | 2008-05-27 | 2012-09-26 | Intra Cellular Therapies Inc | METHOD AND COMPOSITIONS FOR SLEEPING AND OTHER DISORDERS |
AR082163A1 (es) | 2010-07-15 | 2012-11-14 | Hoffmann La Roche | Anticuerpos especificamente ligantes del tslpr humano y metodos de utilizacion de los mismos |
WO2012054438A1 (en) * | 2010-10-22 | 2012-04-26 | Schering Corporation | Anti-pcsk9 |
ES2730978T3 (es) | 2013-08-09 | 2019-11-13 | Astellas Pharma Inc | Anticuerpo anti-receptor de TSLP humana nuevo |
US9790506B2 (en) | 2013-10-02 | 2017-10-17 | The Regents Of The University Of California | Diagnostic and screening methods for atopic dermatitis |
KR20230023817A (ko) | 2013-12-03 | 2023-02-17 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 신규한 방법 |
EP3077416B1 (en) | 2013-12-06 | 2019-06-19 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Thymic stromal lymphopoietin receptor-specific chimeric antigen receptors and methods using same |
DK3347377T3 (da) | 2015-09-09 | 2021-05-10 | Novartis Ag | Tymisk stromal lymfopoietin (TSLP)-bindende antistoffer og fremgangsmåder til anvendelse af antistofferne |
TN2018000076A1 (en) | 2015-09-09 | 2019-07-08 | Novartis Ag | Thymic stromal lymphopoietin (tslp)-binding molecules and methods of using the molecules |
KR20180088906A (ko) | 2015-12-18 | 2018-08-07 | 아스텔라스세이야쿠 가부시키가이샤 | 항인간 tslp 수용체 항체 함유 의약 조성물 |
DK3407888T3 (da) | 2016-01-26 | 2021-04-06 | Intra Cellular Therapies Inc | Pyridopyrroloquinoxalinforbindelser, deres sammensætninger og anvendelser |
WO2017146011A1 (ja) * | 2016-02-22 | 2017-08-31 | 国立大学法人 千葉大学 | アレルギー性鼻炎の診断用バイオマーカー |
US11014925B2 (en) | 2016-03-28 | 2021-05-25 | Intra-Cellular Therapies, Inc. | Co-crystals of 1-(4-fluoro-phenyl)-4-((6bR,1OaS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H,7H- pyrido[3′,4′:4,51_pyrrolo [1,2,3-delqcuinoxalin-8-yl)-butan-1-one with nicotinamide or isonicotinamide |
US11331316B2 (en) | 2016-10-12 | 2022-05-17 | Intra-Cellular Therapies, Inc. | Amorphous solid dispersions |
US10961245B2 (en) | 2016-12-29 | 2021-03-30 | Intra-Cellular Therapies, Inc. | Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders |
JP6987868B2 (ja) | 2016-12-29 | 2022-01-05 | イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. | 有機化合物 |
RU2767410C2 (ru) | 2017-03-24 | 2022-03-17 | Интра-Селлулар Терапиз, Инк. | Новые композиции и способы |
KR20200106498A (ko) * | 2018-01-05 | 2020-09-14 | 이뮤넥스트, 인크. | 항-mct1 항체 및 그의 용도 |
EP3843739A4 (en) | 2018-08-31 | 2022-06-01 | Intra-Cellular Therapies, Inc. | NEW METHODS |
JP2021536453A (ja) | 2018-08-31 | 2021-12-27 | イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. | 新規方法 |
AU2020217012A1 (en) * | 2019-02-01 | 2021-08-19 | Novarock Biotherapeutics, Ltd. | Anti-claudin 18 antibodies and methods of use thereof |
US20220298255A1 (en) * | 2019-05-31 | 2022-09-22 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | E-cadherin activating antibodies and uses thereof |
CN114887053A (zh) * | 2019-11-29 | 2022-08-12 | 康诺亚生物医药科技(成都)有限公司 | 一种tslp相关病症治疗剂的开发和应用 |
CN113501878B (zh) * | 2021-02-03 | 2022-12-02 | 北京智仁美博生物科技有限公司 | 针对人tslp的多种抗体及其用途 |
WO2023028612A2 (en) | 2021-08-27 | 2023-03-02 | Board Of Regents, The University Of Texas System | Anti-tslpr (crlf2) antibodies |
WO2023155132A1 (zh) * | 2022-02-18 | 2023-08-24 | 绍兴守仁医疗健康科技有限公司 | Rac1蛋白单克隆抗体及其制备方法与应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2391124T3 (es) | 2000-06-28 | 2012-11-21 | Amgen Inc. | Moléculas de receptor de linfopoyetina estromal tímica y usos de las mismas |
CA2577631A1 (en) * | 2004-08-20 | 2006-03-02 | Amgen Inc. | Methods and compositions for treating allergic inflammation |
CN101370831B (zh) | 2006-01-13 | 2013-06-19 | Irm责任有限公司 | 用于治疗过敏性疾病的针对胸腺基质淋巴细胞生成素受体的抗体 |
WO2008155365A1 (en) * | 2007-06-20 | 2008-12-24 | Irm Llc | Methods and compositions for treating allergic diseases |
-
2009
- 2009-02-06 AR ARP090100415A patent/AR070346A1/es not_active Application Discontinuation
- 2009-02-06 JP JP2010546045A patent/JP2011511638A/ja active Pending
- 2009-02-06 EP EP09709406.4A patent/EP2250199B1/en active Active
- 2009-02-06 US US12/863,839 patent/US8475793B2/en active Active
- 2009-02-06 CN CN2009801110754A patent/CN101986784A/zh active Pending
- 2009-02-06 WO PCT/US2009/033383 patent/WO2009100324A1/en active Application Filing
- 2009-02-06 CA CA2713935A patent/CA2713935C/en active Active
- 2009-02-06 MX MX2010008688A patent/MX2010008688A/es active IP Right Grant
-
2013
- 2013-07-31 JP JP2013158570A patent/JP2013223516A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP2250199B1 (en) | 2015-09-02 |
US8475793B2 (en) | 2013-07-02 |
CA2713935C (en) | 2016-11-01 |
EP2250199A1 (en) | 2010-11-17 |
CN101986784A (zh) | 2011-03-16 |
JP2013223516A (ja) | 2013-10-31 |
AR070346A1 (es) | 2010-03-31 |
WO2009100324A1 (en) | 2009-08-13 |
US20110020369A1 (en) | 2011-01-27 |
CA2713935A1 (en) | 2009-08-13 |
JP2011511638A (ja) | 2011-04-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
HC | Change of company name or juridical status |