DE69225971D1 - Pen-polymorphismus von menschlichem plättchenmembran-glykoprotein-iiia und diagnostische und therapeutische anwendung davon - Google Patents
Pen-polymorphismus von menschlichem plättchenmembran-glykoprotein-iiia und diagnostische und therapeutische anwendung davonInfo
- Publication number
- DE69225971D1 DE69225971D1 DE69225971T DE69225971T DE69225971D1 DE 69225971 D1 DE69225971 D1 DE 69225971D1 DE 69225971 T DE69225971 T DE 69225971T DE 69225971 T DE69225971 T DE 69225971T DE 69225971 D1 DE69225971 D1 DE 69225971D1
- Authority
- DE
- Germany
- Prior art keywords
- diagnostic
- glycoprotein
- iiia
- polymorphism
- pen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 102000008607 Integrin beta3 Human genes 0.000 abstract 2
- 108010020950 Integrin beta3 Proteins 0.000 abstract 2
- 230000000961 alloantigen Effects 0.000 abstract 1
- 208000035850 clinical syndrome Diseases 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70546—Integrin superfamily
- C07K14/70557—Integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72132191A | 1991-07-01 | 1991-07-01 | |
| PCT/US1992/005391 WO1993001315A1 (en) | 1991-07-01 | 1992-07-01 | PEN POLYMORPHISM OF HUMAN PLATELET MEMBRANE GLYCOPROTEIN IIIa AND DIAGNOSTIC AND THERAPEUTIC APPLICATION THEREOF |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69225971D1 true DE69225971D1 (de) | 1998-07-23 |
Family
ID=24897491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69225971T Expired - Lifetime DE69225971D1 (de) | 1991-07-01 | 1992-07-01 | Pen-polymorphismus von menschlichem plättchenmembran-glykoprotein-iiia und diagnostische und therapeutische anwendung davon |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5972601A (de) |
| EP (1) | EP0593572B1 (de) |
| JP (1) | JPH06508993A (de) |
| AT (1) | ATE167525T1 (de) |
| AU (1) | AU2254792A (de) |
| DE (1) | DE69225971D1 (de) |
| WO (1) | WO1993001315A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2254792A (en) * | 1991-07-01 | 1993-02-11 | Blood Center Of Southeastern Wisconsin, The | Pen polymorphism of human platelet membrane glycoprotein iiia and diagnostic and therapeutic application thereof |
| US6013853A (en) * | 1992-02-14 | 2000-01-11 | The University Of Texas System | Continuous release polymeric implant carrier |
| US5876452A (en) * | 1992-02-14 | 1999-03-02 | Board Of Regents, University Of Texas System | Biodegradable implant |
| ATE364717T1 (de) * | 1996-01-17 | 2007-07-15 | Sequenom Gemini Ltd | Diagnose durch bestimmung von polymorphismen in der promoterregion des tgf-beta 1 gens |
| EP1356298B1 (de) | 2000-11-30 | 2011-05-18 | Crawford Healthcare Holdings Limited | Krankheitsdiagnose |
| US6596489B2 (en) | 2001-03-30 | 2003-07-22 | Applied Gene Technologies | Methods and compositions for analyzing nucleotide sequence mismatches using RNase H |
| CA2897983A1 (en) | 2004-02-06 | 2005-08-18 | Canadian Blood Services | A method for the simultaneous determination of blood group and platelet antigen genotypes |
| US20100285478A1 (en) | 2009-03-27 | 2010-11-11 | Life Technologies Corporation | Methods, Compositions, and Kits for Detecting Allelic Variants |
| EP2376659B1 (de) | 2008-12-17 | 2015-12-02 | Life Technologies Corporation | Verfahren, zusammensetzungen und kits für den nachweis von allelen varianten |
| CN101445832B (zh) * | 2008-12-23 | 2011-09-14 | 广州益善生物技术有限公司 | Pik3ca基因突变的检测探针、液相芯片及其检测方法 |
| CN101487051B (zh) * | 2009-02-24 | 2011-07-20 | 广州益善生物技术有限公司 | Braf基因突变的检测探针、液相芯片及其检测方法 |
| JP5940771B2 (ja) * | 2010-07-12 | 2016-06-29 | アークレイ株式会社 | ａｂｌ遺伝子多型の検出用プローブおよびその用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4526716A (en) * | 1981-11-20 | 1985-07-02 | The Ohio State University | Antigenic modification of polypeptides |
| CA2000048A1 (en) * | 1988-10-03 | 1990-04-03 | Edward F. Plow | Peptides and antibodies that inhibit integrin-ligand bindin g |
| ATE217887T1 (de) * | 1988-12-22 | 2002-06-15 | Genentech Inc | Verfahren zur herstellung von wasserlöslichen polypeptiden |
| US5091302A (en) * | 1989-04-27 | 1992-02-25 | The Blood Center Of Southeastern Wisconsin, Inc. | Polymorphism of human platelet membrane glycoprotein iiia and diagnostic and therapeutic applications thereof |
| JPH02300664A (ja) * | 1989-05-16 | 1990-12-12 | Olympus Optical Co Ltd | 抗血小板抗体検出用試薬 |
| US5436163A (en) * | 1989-12-01 | 1995-07-25 | The Blood Center Of Southeastern Wisconsin | Polymorphism of human platelet membrane glycoprotein IIb and diagnostic applications thereof |
| US5177188A (en) * | 1990-12-03 | 1993-01-05 | The Scripps Research Institute | Methods and compositions for diagnosing chronic immune thrombocytopenic purpura |
| AU2254792A (en) * | 1991-07-01 | 1993-02-11 | Blood Center Of Southeastern Wisconsin, The | Pen polymorphism of human platelet membrane glycoprotein iiia and diagnostic and therapeutic application thereof |
-
1992
- 1992-07-01 AU AU22547/92A patent/AU2254792A/en not_active Abandoned
- 1992-07-01 JP JP5502253A patent/JPH06508993A/ja active Pending
- 1992-07-01 DE DE69225971T patent/DE69225971D1/de not_active Expired - Lifetime
- 1992-07-01 WO PCT/US1992/005391 patent/WO1993001315A1/en active IP Right Grant
- 1992-07-01 AT AT92914287T patent/ATE167525T1/de not_active IP Right Cessation
- 1992-07-01 EP EP92914287A patent/EP0593572B1/de not_active Expired - Lifetime
-
1995
- 1995-06-07 US US08/484,201 patent/US5972601A/en not_active Expired - Lifetime
- 1995-06-07 US US08/482,174 patent/US5780229A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0593572B1 (de) | 1998-06-17 |
| AU2254792A (en) | 1993-02-11 |
| EP0593572A1 (de) | 1994-04-27 |
| WO1993001315A1 (en) | 1993-01-21 |
| JPH06508993A (ja) | 1994-10-13 |
| EP0593572A4 (en) | 1994-08-24 |
| US5780229A (en) | 1998-07-14 |
| US5972601A (en) | 1999-10-26 |
| ATE167525T1 (de) | 1998-07-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE161055T1 (de) | Polymorphie des glykoproteins iiia der menschlichen blutplättchenmembran und diagnostische applikation davon | |
| DE69225971D1 (de) | Pen-polymorphismus von menschlichem plättchenmembran-glykoprotein-iiia und diagnostische und therapeutische anwendung davon | |
| DE69533942D1 (de) | Behandlung von lösungen roter blutkörperchen mit antiviralen wirkstoffen | |
| PT939804E (pt) | Neutroquina alfa | |
| DE59010941D1 (de) | TNF-Rezeptor, TNF bindende Proteine und dafür kodierende DNAs | |
| DE69503129T2 (de) | Pteridin-nukleotidderivate als fluoreszierende sonden | |
| NO903059L (no) | Ligander og reseptorer omfattende nevnte ligander, fremgangsmaate for deres fremstilling og anvendelse. | |
| DE69131249D1 (de) | Durch menschliche lymphozyten produzierte proteine, die für diese proteine kodierende dns und pharmazeutische und biologische verwendungen | |
| ATE353974T1 (de) | Verfahren, zusammensetzungen und kits zur identifizierung und überwachung von brustkrebs | |
| BR0111125A (pt) | Moléculas de ácido nucléico de nrg-2, polipeptìdeos, e métodos diagnóstico e terapêuticos | |
| DE3783282T2 (de) | Varianten von lav-viren, deren dns- und proteinkomponenten und deren verwendung, insbesondere zu diagnostischen zwecken und zur herstellung von immunogenen zusammensetzungen. | |
| DE60235005D1 (de) | Nachweis der instabilität von mikrosatelliten und | |
| ATE209684T1 (de) | Dna-sequenzen für matrix-metallproteasen, ihre herstellung und verwendung | |
| ATE121793T1 (de) | Detektion von pneumocystis carinii durch die verwendung von nukleinsäuresonden. | |
| ATE88500T1 (de) | Dna-sequenzen, die fuer proteine mit der biologischen aktivitaet der husi-typi-inhibitoren codieren, gentechnologische verfahren zur herstellung dieser proteine und diese proteine enthaltende arzneimittel. | |
| DE3751307D1 (de) | Zubereitungen und verfahren für klone, die, mit mehrfacharzneimittelresistenz assoziierte, dna-sequenzen in menschlichen zellen enthalten. | |
| DE69329656D1 (de) | Methoden zur detektion und behandlung von individuen mit abnormalen hla-a2/tyrosinase-peptidantigenen exprimierenden zellen | |
| DE69022362D1 (de) | Nukleinsäuresonden für die detektion von neisseria gonorrhoeae. | |
| DE69033810T2 (de) | Herstellung und verwendung des menschlichen nm23-h2-proteins und dagegen gerichtete antikörper | |
| ATE213279T1 (de) | Diagnoseverfahren und vorrichtung zum nachweis der prädisposition zu bestimmten krankheitszuständen, insbesondere osteoporose, auf basis von il-6 genpolymorphismus | |
| Soltys et al. | IFN-β alters neurotrophic factor expression in T cells isolated from multiple sclerosis patients-implication of novel neurotensin/NTSR1 pathway in neuroprotection | |
| Davrinche et al. | Genetic variants of human B component (BF system) and alpha-1-antitrypsin (PI system) in a population from Sardinia | |
| DE3850933D1 (de) | Anticoagulatorisches Protein PP4-X, seine Herstellung und Verwendung. | |
| SE9403953D0 (sv) | Sequence-based diagnosis | |
| BR9814866A (pt) | Uso de oligÈmeros de ácido poliamida nucléicopara produzir uma resposta biológica |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de |