DE69521281D1 - Verfahren zur Herstellung von menschlichem oder humanem Matrilysin mittels rekombinanter DNA. - Google Patents

Verfahren zur Herstellung von menschlichem oder humanem Matrilysin mittels rekombinanter DNA.

Info

Publication number
DE69521281D1
DE69521281D1 DE69521281T DE69521281T DE69521281D1 DE 69521281 D1 DE69521281 D1 DE 69521281D1 DE 69521281 T DE69521281 T DE 69521281T DE 69521281 T DE69521281 T DE 69521281T DE 69521281 D1 DE69521281 D1 DE 69521281D1
Authority
DE
Germany
Prior art keywords
human
production
recombinant dna
matrilysin
human matrilysin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69521281T
Other languages
English (en)
Other versions
DE69521281T2 (de
Inventor
Yasunoti Kihira
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oriental Yeast Co Ltd
Original Assignee
Oriental Yeast Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oriental Yeast Co Ltd filed Critical Oriental Yeast Co Ltd
Publication of DE69521281D1 publication Critical patent/DE69521281D1/de
Application granted granted Critical
Publication of DE69521281T2 publication Critical patent/DE69521281T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C12N9/6491—Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DE69521281T 1994-09-30 1995-09-25 Verfahren zur Herstellung von menschlichem oder humanem Matrilysin mittels rekombinanter DNA. Expired - Lifetime DE69521281T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6259576A JP2938352B2 (ja) 1994-09-30 1994-09-30 組換え人マトリライシンの製造方法

Publications (2)

Publication Number Publication Date
DE69521281D1 true DE69521281D1 (de) 2001-07-19
DE69521281T2 DE69521281T2 (de) 2002-03-07

Family

ID=17336046

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69521281T Expired - Lifetime DE69521281T2 (de) 1994-09-30 1995-09-25 Verfahren zur Herstellung von menschlichem oder humanem Matrilysin mittels rekombinanter DNA.

Country Status (4)

Country Link
US (1) US6010893A (de)
EP (1) EP0718403B1 (de)
JP (1) JP2938352B2 (de)
DE (1) DE69521281T2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2741214C (en) * 2008-10-21 2016-07-26 Hiroshi Nakatake Process for preparing inclusion body-forming protein
TWI743023B (zh) 2014-05-21 2021-10-21 日商Ｋｍ生物醫藥股份有限公司 基質金屬蛋白酶 7(mmp-7)聚集體之單體化方法
CN112694527B (zh) * 2020-12-25 2022-09-09 山东睿鹰制药集团有限公司 一种重组人干扰素-κ包涵体的纯化和复性方法
CN114032252B (zh) * 2021-11-01 2022-04-22 武汉爱博泰克生物科技有限公司 一种重组状态人源mmp-7蛋白的表达方法及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652639A (en) * 1982-05-06 1987-03-24 Amgen Manufacture and expression of structural genes
US5240831A (en) * 1991-01-10 1993-08-31 Board Of Regents, The University Of Texas Methods and compositions for the expression of biologically active eukaryotic cytochrome p45os in bacteria

Also Published As

Publication number Publication date
US6010893A (en) 2000-01-04
EP0718403B1 (de) 2001-06-13
EP0718403A1 (de) 1996-06-26
DE69521281T2 (de) 2002-03-07
JPH0898693A (ja) 1996-04-16
JP2938352B2 (ja) 1999-08-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition