JP5681638B2 - 抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 - Google Patents
抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 Download PDFInfo
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- JP5681638B2 JP5681638B2 JP2011540819A JP2011540819A JP5681638B2 JP 5681638 B2 JP5681638 B2 JP 5681638B2 JP 2011540819 A JP2011540819 A JP 2011540819A JP 2011540819 A JP2011540819 A JP 2011540819A JP 5681638 B2 JP5681638 B2 JP 5681638B2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Oncology (AREA)
- Virology (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12109208P | 2008-12-09 | 2008-12-09 | |
| US61/121,092 | 2008-12-09 | ||
| PCT/US2009/067104 WO2010077634A1 (en) | 2008-12-09 | 2009-12-08 | Anti-pd-l1 antibodies and their use to enhance t-cell function |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015003298A Division JP6178349B2 (ja) | 2008-12-09 | 2015-01-09 | 抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012511329A JP2012511329A (ja) | 2012-05-24 |
| JP2012511329A5 JP2012511329A5 (OSRAM) | 2014-03-13 |
| JP5681638B2 true JP5681638B2 (ja) | 2015-03-11 |
Family
ID=42097246
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011540819A Active JP5681638B2 (ja) | 2008-12-09 | 2009-12-08 | 抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 |
| JP2015003298A Active JP6178349B2 (ja) | 2008-12-09 | 2015-01-09 | 抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 |
| JP2017075787A Active JP6509935B2 (ja) | 2008-12-09 | 2017-04-06 | 抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 |
| JP2019071460A Pending JP2019122409A (ja) | 2008-12-09 | 2019-04-03 | 抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 |
| JP2021196323A Active JP7332671B2 (ja) | 2008-12-09 | 2021-12-02 | 抗pd-l1抗体およびt細胞機能を増強するためのそれらの使用 |
| JP2023131222A Pending JP2023154034A (ja) | 2008-12-09 | 2023-08-10 | 抗pd-l1抗体およびt細胞機能を増強するためのそれらの使用 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015003298A Active JP6178349B2 (ja) | 2008-12-09 | 2015-01-09 | 抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 |
| JP2017075787A Active JP6509935B2 (ja) | 2008-12-09 | 2017-04-06 | 抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 |
| JP2019071460A Pending JP2019122409A (ja) | 2008-12-09 | 2019-04-03 | 抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 |
| JP2021196323A Active JP7332671B2 (ja) | 2008-12-09 | 2021-12-02 | 抗pd-l1抗体およびt細胞機能を増強するためのそれらの使用 |
| JP2023131222A Pending JP2023154034A (ja) | 2008-12-09 | 2023-08-10 | 抗pd-l1抗体およびt細胞機能を増強するためのそれらの使用 |
Country Status (41)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015091260A (ja) * | 2008-12-09 | 2015-05-14 | ジェネンテック, インコーポレイテッド | 抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 |
Families Citing this family (1755)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7030219B2 (en) | 2000-04-28 | 2006-04-18 | Johns Hopkins University | B7-DC, Dendritic cell co-stimulatory molecules |
| US20040121370A1 (en) | 2002-09-11 | 2004-06-24 | Genentech, Inc. | Novel composition and methods for the treatment of immune related diseases |
| EP1629105B1 (en) | 2003-04-29 | 2010-09-01 | AVI BioPharma, Inc. | Compositions for enhancing transport and antisense efficacy of nucleic acid analog into cells |
| US8067571B2 (en) | 2005-07-13 | 2011-11-29 | Avi Biopharma, Inc. | Antibacterial antisense oligonucleotide and method |
| US20100016215A1 (en) | 2007-06-29 | 2010-01-21 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| US9090894B2 (en) * | 2007-12-17 | 2015-07-28 | California Institute Of Technology | Modulating immune system development and function through microRNA MIR-146 |
| PT2238170T (pt) | 2008-01-31 | 2017-02-21 | Inserm - Inst Nat De La Santé Et De La Rech Médicale | Anticorpos contra cd39 humano e seu uso para inibição da actividade de células t reguladoras |
| WO2009114085A2 (en) | 2008-03-03 | 2009-09-17 | The University Of Miami | Allogeneic cancer cell-based immunotherapy |
| EP3605088A1 (en) | 2008-04-09 | 2020-02-05 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| DK2853269T3 (da) | 2008-05-19 | 2019-08-05 | Advaxis Inc | Dobbelt indgivelsessystem til heterologe antigener, der omfatter en rekombinant Listeria-stamme svækket ved mutation af dal/dat og deletion af ActA, der omfatter et nukleinsyremolekyle, der koder for et listeriolysin O-prostataspecifikt antigenfusionsprotein |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| EA023148B1 (ru) | 2008-08-25 | 2016-04-29 | Эмплиммьюн, Инк. | Композиции на основе антагонистов pd-1 и их применение |
| US8268314B2 (en) | 2008-10-08 | 2012-09-18 | Hoffmann-La Roche Inc. | Bispecific anti-VEGF/anti-ANG-2 antibodies |
| SI2415470T1 (sl) | 2009-03-30 | 2016-12-30 | Eisai R&D Management Co., Ltd. | Liposomski sestavek |
| EP2482849B1 (en) | 2009-09-30 | 2018-06-06 | Memorial Sloan-Kettering Cancer Center | Combination immunotherapy for the treatment of cancer |
| US8741591B2 (en) | 2009-10-09 | 2014-06-03 | The Research Foundation For The State University Of New York | pH-insensitive glucose indicator protein |
| US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
| EP2504028A4 (en) * | 2009-11-24 | 2014-04-09 | Amplimmune Inc | SIMULTANEOUS INHIBITION OF PD-L1 / PD-L2 |
| CN104961829B (zh) * | 2009-11-24 | 2018-08-21 | 米迪缪尼有限公司 | 针对b7-h1的靶向结合剂 |
| PT2949670T (pt) | 2009-12-10 | 2019-05-20 | Hoffmann La Roche | Anticorpos que se ligam preferencialmente ao domínio extracelular 4 do csf1r e respetiva utilização |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015091260A (ja) * | 2008-12-09 | 2015-05-14 | ジェネンテック, インコーポレイテッド | 抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 |
| US9920123B2 (en) | 2008-12-09 | 2018-03-20 | Genentech, Inc. | Anti-PD-L1 antibodies, compositions and articles of manufacture |
| JP2019122409A (ja) * | 2008-12-09 | 2019-07-25 | ジェネンテック, インコーポレイテッド | 抗pd−l1抗体およびt細胞機能を増強するためのそれらの使用 |
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| HK1207387B (zh) | 抗-pd-l1抗体及它们用於增强t细胞功能的用途 |
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