MA49849A - Traitement du cancer du sein triple négatif ou du cancer colorectal comportant des métastases hépatiques par un anticorps anti-pd-l1 et un virus oncolytique - Google Patents
Traitement du cancer du sein triple négatif ou du cancer colorectal comportant des métastases hépatiques par un anticorps anti-pd-l1 et un virus oncolytiqueInfo
- Publication number
- MA49849A MA49849A MA049849A MA49849A MA49849A MA 49849 A MA49849 A MA 49849A MA 049849 A MA049849 A MA 049849A MA 49849 A MA49849 A MA 49849A MA 49849 A MA49849 A MA 49849A
- Authority
- MA
- Morocco
- Prior art keywords
- antibody
- treatment
- oncolytic virus
- breast cancer
- colorectal cancer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/763—Herpes virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16632—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762542046P | 2017-08-07 | 2017-08-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA49849A true MA49849A (fr) | 2020-06-17 |
Family
ID=63556436
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA049849A MA49849A (fr) | 2017-08-07 | 2018-08-06 | Traitement du cancer du sein triple négatif ou du cancer colorectal comportant des métastases hépatiques par un anticorps anti-pd-l1 et un virus oncolytique |
Country Status (11)
Country | Link |
---|---|
US (1) | US20200254037A1 (fr) |
EP (1) | EP3664844A1 (fr) |
JP (1) | JP2020530003A (fr) |
CN (1) | CN111246883A (fr) |
AR (1) | AR112405A1 (fr) |
AU (1) | AU2018314227A1 (fr) |
CA (1) | CA3071599A1 (fr) |
MA (1) | MA49849A (fr) |
MX (1) | MX2020001451A (fr) |
TW (1) | TW201912173A (fr) |
WO (1) | WO2019032431A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10596257B2 (en) | 2016-01-08 | 2020-03-24 | Hoffmann-La Roche Inc. | Methods of treating CEA-positive cancers using PD-1 axis binding antagonists and anti-CEA/anti-CD3 bispecific antibodies |
CA3131529A1 (fr) * | 2019-03-05 | 2020-09-10 | Amgen Inc. | Utilisation de virus oncolytiques pour le traitement du cancer |
CN114057877A (zh) * | 2020-08-07 | 2022-02-18 | 百奥泰生物制药股份有限公司 | 抗pd-l1抗体及其应用 |
EP4196574A2 (fr) * | 2020-08-14 | 2023-06-21 | Mayo Foundation for Medical Education and Research | Matériels et méthodes pour l'ablation d'un tissu biologique |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4342776A (en) | 1979-11-05 | 1982-08-03 | Merck & Co., Inc. | 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase |
US4399276A (en) | 1981-01-09 | 1983-08-16 | Kabushiki Kaisha Yakult Honsha | 7-Substituted camptothecin derivatives |
JPS5839685A (ja) | 1981-09-04 | 1983-03-08 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体及びその製造法 |
US4473692A (en) | 1981-09-04 | 1984-09-25 | Kabushiki Kaisha Yakult Honsha | Camptothecin derivatives and process for preparing same |
JPS58154582A (ja) | 1982-03-10 | 1983-09-14 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体およびその製造法 |
US4526988A (en) | 1983-03-10 | 1985-07-02 | Eli Lilly And Company | Difluoro antivirals and intermediate therefor |
JPS6019790A (ja) | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
EP0184365B1 (fr) | 1984-12-04 | 1993-08-04 | Eli Lilly And Company | Traitement de tumeurs chez les mammifères |
US5223608A (en) | 1987-08-28 | 1993-06-29 | Eli Lilly And Company | Process for and intermediates of 2',2'-difluoronucleosides |
US5004758A (en) | 1987-12-01 | 1991-04-02 | Smithkline Beecham Corporation | Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells |
NZ235329A (en) | 1989-09-15 | 1992-01-29 | Res Triangle Inst | 20(s or rs)-camptothecin derivatives and pharmaceutical compositions |
US6770274B1 (en) | 1990-09-14 | 2004-08-03 | The General Hospital Corporation | Viral mutant HSV mediated destruction of neoplastic cells |
FR2707988B1 (fr) | 1993-07-21 | 1995-10-13 | Pf Medicament | Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant. |
US5585096A (en) | 1994-06-23 | 1996-12-17 | Georgetown University | Replication-competent herpes simplex virus mediates destruction of neoplastic cells |
US5728379A (en) | 1994-06-23 | 1998-03-17 | Georgetown University | Tumor- or cell-specific herpes simplex virus replication |
US6699468B1 (en) | 1994-06-23 | 2004-03-02 | Georgetown University | Replication-competent herpes simplex virus mediates destruction of neoplastic cells |
US5824318A (en) | 1996-07-24 | 1998-10-20 | American Cyanamid Company | Avirulent herpetic viruses useful as tumoricidal agents and vaccines |
US6379674B1 (en) | 1997-08-12 | 2002-04-30 | Georgetown University | Use of herpes vectors for tumor therapy |
CA2346866A1 (fr) | 1998-10-16 | 2000-04-27 | The Government Of The United States Of America As Represented By The Sec Retary Of The Department Of Health And Human Services | Therapie combinee avec antagoniste du polypeptide vasoactif intestinal |
WO2000040734A1 (fr) | 1998-12-31 | 2000-07-13 | Arch Development Corporation | Virus de l'herpes simplex recombinant utile dans le traitement des maladies neoplasiques |
WO2000054795A1 (fr) | 1999-03-15 | 2000-09-21 | The Trustees Of The University Of Pennsylvania | Therapie combinee consistant a administrer un agent chimiotherapeutique et un virus oncolytique pour tuer des cellules cancereuses chez un sujet |
US6764675B1 (en) | 1999-06-08 | 2004-07-20 | The Uab Research Foundation | Herpes simplex virus expressing foreign genes and method for treating cancers therewith |
AU2695101A (en) | 2000-01-21 | 2001-07-31 | Biovex Ltd | Virus strains |
ATE508635T1 (de) | 2001-03-27 | 2011-05-15 | Catherex Inc | Virusvektoren und ihre verwendung bei therapeutischen methoden |
US7731952B2 (en) | 2004-06-24 | 2010-06-08 | New York University | Avirulent oncolytic herpes simplex virus strains engineered to counter the innate host response |
RS54271B1 (en) | 2005-07-01 | 2016-02-29 | E. R. Squibb & Sons, L.L.C. | HUMAN MONOCLONIC ANTIBODIES FOR LIGAND PROGRAMMED DEATH 1 (PD-L1) |
CN101230335B (zh) | 2007-01-22 | 2010-08-11 | 北京奥源和力生物技术有限公司 | 单纯疱疹病毒和重组病毒及宿主细胞及其药物组合物 |
CN101230334B (zh) | 2007-01-22 | 2011-06-01 | 北京奥源和力生物技术有限公司 | 单纯疱疹病毒和重组病毒及宿主细胞及其药物组合物 |
CN114835812A (zh) | 2008-12-09 | 2022-08-02 | 霍夫曼-拉罗奇有限公司 | 抗-pd-l1抗体及它们用于增强t细胞功能的用途 |
LT3279215T (lt) | 2009-11-24 | 2020-04-10 | Medimmune Limited | Tiksliniai surišantys agentai prieš b7-h1 |
DK2699264T3 (en) | 2011-04-20 | 2018-06-25 | Medimmune Llc | ANTIBODIES AND OTHER MOLECULES BINDING B7-H1 AND PD-1 |
WO2013006795A2 (fr) | 2011-07-07 | 2013-01-10 | Humanitas International Foundation | Compositions antivirales et leurs méthodes d'utilisation |
EP3553086A1 (fr) | 2012-05-31 | 2019-10-16 | Sorrento Therapeutics Inc. | Protéines de liaison à un antigène se liant à pd-l1 |
US10544225B2 (en) | 2014-07-03 | 2020-01-28 | Beigene, Ltd. | Anti-PD-L1 antibodies and their use as therapeutics and diagnostics |
CA2955084C (fr) * | 2014-07-16 | 2023-08-29 | Transgene Sa | Association de virus oncolytiques ayant des modulateurs de points de controle immunitaires |
EP4245376A3 (fr) | 2014-10-14 | 2023-12-13 | Novartis AG | Molécules d'anticorps de pd-l1 et leurs utilisations |
CA3011157A1 (fr) * | 2016-01-11 | 2017-07-20 | Turnstone Limited Partnership | Polytherapie a base d'un virus oncolytique et d'un inhibiteur de point de controle |
WO2018170133A1 (fr) * | 2017-03-15 | 2018-09-20 | Amgen Inc. | Utilisation de virus oncolytiques, seuls ou en combinaison avec un inhibiteur de point de contrôle immunitaire, pour le traitement du cancer |
-
2018
- 2018-08-06 MX MX2020001451A patent/MX2020001451A/es unknown
- 2018-08-06 TW TW107127241A patent/TW201912173A/zh unknown
- 2018-08-06 EP EP18768988.0A patent/EP3664844A1/fr not_active Withdrawn
- 2018-08-06 AR ARP180102234 patent/AR112405A1/es unknown
- 2018-08-06 US US16/637,600 patent/US20200254037A1/en not_active Abandoned
- 2018-08-06 WO PCT/US2018/045328 patent/WO2019032431A1/fr unknown
- 2018-08-06 AU AU2018314227A patent/AU2018314227A1/en not_active Abandoned
- 2018-08-06 CN CN201880065031.1A patent/CN111246883A/zh active Pending
- 2018-08-06 CA CA3071599A patent/CA3071599A1/fr not_active Abandoned
- 2018-08-06 MA MA049849A patent/MA49849A/fr unknown
- 2018-08-06 JP JP2020506208A patent/JP2020530003A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2019032431A1 (fr) | 2019-02-14 |
AU2018314227A8 (en) | 2020-10-08 |
CA3071599A1 (fr) | 2019-02-14 |
TW201912173A (zh) | 2019-04-01 |
CN111246883A (zh) | 2020-06-05 |
AU2018314227A1 (en) | 2020-02-06 |
EP3664844A1 (fr) | 2020-06-17 |
AR112405A1 (es) | 2019-10-23 |
MX2020001451A (es) | 2020-08-06 |
US20200254037A1 (en) | 2020-08-13 |
JP2020530003A (ja) | 2020-10-15 |
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