MA40737A - Déterminants de la réponse d'un cancer à une immunothérapie par blocage de pd-1 - Google Patents
Déterminants de la réponse d'un cancer à une immunothérapie par blocage de pd-1Info
- Publication number
- MA40737A MA40737A MA040737A MA40737A MA40737A MA 40737 A MA40737 A MA 40737A MA 040737 A MA040737 A MA 040737A MA 40737 A MA40737 A MA 40737A MA 40737 A MA40737 A MA 40737A
- Authority
- MA
- Morocco
- Prior art keywords
- determinants
- immunotherapy
- blocked
- cancer response
- cancer
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 238000009169 immunotherapy Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462083088P | 2014-11-21 | 2014-11-21 | |
US201562132381P | 2015-03-12 | 2015-03-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA40737A true MA40737A (fr) | 2017-07-04 |
Family
ID=56014697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA040737A MA40737A (fr) | 2014-11-21 | 2015-11-22 | Déterminants de la réponse d'un cancer à une immunothérapie par blocage de pd-1 |
Country Status (9)
Country | Link |
---|---|
US (3) | US20180291074A1 (fr) |
EP (1) | EP3220950A4 (fr) |
JP (3) | JP7173733B2 (fr) |
CN (2) | CN114672559A (fr) |
AU (2) | AU2015349644B2 (fr) |
CA (1) | CA2968059A1 (fr) |
HK (1) | HK1244440A1 (fr) |
MA (1) | MA40737A (fr) |
WO (1) | WO2016081947A2 (fr) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104479018B (zh) | 2008-12-09 | 2018-09-21 | 霍夫曼-拉罗奇有限公司 | 抗-pd-l1抗体及它们用于增强t细胞功能的用途 |
MY184154A (en) | 2013-12-12 | 2021-03-23 | Shanghai hengrui pharmaceutical co ltd | Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof |
JP6920989B2 (ja) | 2014-10-29 | 2021-08-18 | ファイヴ プライム セラピューティクス インク | がんのための併用療法 |
MA40737A (fr) * | 2014-11-21 | 2017-07-04 | Memorial Sloan Kettering Cancer Center | Déterminants de la réponse d'un cancer à une immunothérapie par blocage de pd-1 |
GB201516047D0 (en) | 2015-09-10 | 2015-10-28 | Cancer Rec Tech Ltd | Method |
IL259931B2 (en) | 2015-12-16 | 2024-02-01 | Gritstone Bio Inc | Identification of neo-antigens, preparation, and use |
CN109196121B (zh) * | 2016-02-29 | 2022-01-04 | 基因泰克公司 | 用于癌症的治疗和诊断方法 |
JP2019509282A (ja) | 2016-02-29 | 2019-04-04 | ファウンデーション・メディシン・インコーポレイテッド | 癌の治療方法 |
JP6918816B2 (ja) * | 2016-03-01 | 2021-08-18 | ノース カロライナ ステート ユニバーシティ | マイクロニードルパッチ支援送達による強化されたがん免疫療法 |
US11318185B2 (en) | 2016-03-02 | 2022-05-03 | Toray Industries, Inc. | Immunogenic peptides of SCD1 protein |
CA3024508A1 (fr) | 2016-05-27 | 2017-11-30 | Agenus Inc. | Anticorps anti-tim-3 et leurs methodes d'utilisation |
JP6910653B2 (ja) * | 2016-07-01 | 2021-07-28 | 国立大学法人東北大学 | 免疫チェックポイント阻害薬使用における免疫関連副作用の予測方法 |
KR20190038935A (ko) | 2016-08-25 | 2019-04-09 | 난토믹스, 엘엘씨 | 면역요법 마커들 및 그 용도들(immunotherapy markers and uses therefor) |
TWI775781B (zh) * | 2016-10-06 | 2022-09-01 | 美商建南德克公司 | 癌症之治療性及診斷性方法 |
CA3039402A1 (fr) | 2016-10-07 | 2018-04-12 | Omniseq, Inc. | Procedes et systemes pour determiner des therapies personnalisees |
US20190369096A1 (en) * | 2017-01-13 | 2019-12-05 | Nantbio, Inc. | Validation of neoepitope-based treatment |
EP3576781B9 (fr) * | 2017-01-18 | 2024-03-06 | Icahn School of Medicine at Mount Sinai | Néoantigènes et leurs utilisations dans le traitement du cancer |
WO2018144775A1 (fr) | 2017-02-01 | 2018-08-09 | Modernatx, Inc. | Compositions thérapeutiques immunomodulatrices d'arnm codant pour des peptides de mutation d'activation d'oncogènes |
ES2885178T3 (es) * | 2017-02-06 | 2021-12-13 | Novartis Ag | Método para la predicción de respuesta a la inmunoterapia |
US20190360051A1 (en) * | 2017-02-17 | 2019-11-28 | Stichting Vumc | Swarm intelligence-enhanced diagnosis and therapy selection for cancer using tumor- educated platelets |
KR20190142767A (ko) * | 2017-03-20 | 2019-12-27 | 제노세아 바이오사이언스, 인코퍼레이티드 | 치료 방법 |
AU2018243754A1 (en) * | 2017-03-31 | 2019-10-17 | Bristol-Myers Squibb Company | Methods of treating tumor |
GB201710815D0 (en) * | 2017-07-05 | 2017-08-16 | Francis Crick Inst Ltd | Method |
JP2020527351A (ja) * | 2017-07-21 | 2020-09-10 | ジェネンテック, インコーポレイテッド | がんの治療法及び診断法 |
CN111148996A (zh) * | 2017-07-28 | 2020-05-12 | 百时美施贵宝公司 | 用于检查点抑制剂的预测性外周血生物标志物 |
JP2020535119A (ja) * | 2017-09-13 | 2020-12-03 | ファイヴ プライム セラピューティクス インク | 膵臓がんの抗csf1rおよび抗pd−1抗体組合せ併用療法 |
WO2019055860A1 (fr) * | 2017-09-15 | 2019-03-21 | The Texas A&M University System | Méthodes d'amélioration de l'immunothérapie dans le traitement du cancer |
CA3076894A1 (fr) | 2017-09-25 | 2019-03-28 | Memorial Sloan Kettering Cancer Center | Fardeau de mutations et immunotherapie des points de controle |
CA3076918A1 (fr) * | 2017-10-02 | 2019-04-11 | Curematch, Inc. | Procede de prediction de l'antigenicite et/ou de l'immunogenicite d'un neo-peptide derive d'une tumeur, a l'aide de motifs de signature mutationnelle |
CN111465989A (zh) | 2017-10-10 | 2020-07-28 | 磨石肿瘤生物技术公司 | 使用热点进行的新抗原鉴别 |
US11810672B2 (en) | 2017-10-12 | 2023-11-07 | Nantomics, Llc | Cancer score for assessment and response prediction from biological fluids |
US20200239577A1 (en) | 2017-10-15 | 2020-07-30 | Bristol-Myers Squibb Company | Methods of treating tumor |
CA3079253A1 (fr) | 2017-11-03 | 2019-05-09 | Guardant Health, Inc. | Normalisation de la charge de mutation tumorale |
AU2018367925A1 (en) * | 2017-11-17 | 2020-07-02 | Gmdx Co Pty Ltd | Systems and methods for predicting the efficacy of cancer therapy |
JP2021503897A (ja) | 2017-11-22 | 2021-02-15 | グリットストーン オンコロジー インコーポレイテッド | 新生抗原のためのジャンクションエピトープ提示の低減 |
CN110770838B (zh) * | 2017-12-01 | 2023-12-19 | Illumina公司 | 用于确定体细胞突变克隆性的方法和系统 |
EP3788173B1 (fr) * | 2018-05-03 | 2023-11-29 | F. Hoffmann-La Roche AG | Marqueur de substitution et procédé de mesure de charge de mutation de tumeur |
JP2021522298A (ja) * | 2018-05-04 | 2021-08-30 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | 癌治療のためのPD−1/PD−L1、TGFβおよびDNA−PKの同時阻害 |
SG11202100344WA (en) | 2018-07-23 | 2021-02-25 | Guardant Health Inc | Methods and systems for adjusting tumor mutational burden by tumor fraction and coverage |
WO2020021119A1 (fr) | 2018-07-27 | 2020-01-30 | F. Hoffmann-La Roche Ag | Procédé de surveillance de l'efficacité d'immunothérapie de patients atteints d'un cancer |
EP3845236A4 (fr) * | 2018-08-29 | 2022-07-27 | Tokyo Metropolitan Institute of Medical Science | Agent antitumoral ciblant un substrat de tyrosine kinase régulée par hgf (hgs) |
JP2021535489A (ja) | 2018-08-31 | 2021-12-16 | ガーダント ヘルス, インコーポレイテッド | 無細胞dnaにおけるマイクロサテライト不安定性の検出 |
JP2022513068A (ja) * | 2018-11-15 | 2022-02-07 | パーソナル ゲノム ダイアグノスティクス インコーポレイテッド | 免疫療法で治療されたがん患者の応答の予測を改善する方法 |
US20200190598A1 (en) * | 2018-12-12 | 2020-06-18 | Medimmune, Llc | Blood-based tumor mutation burden predicts overall survival in nsclc |
WO2020252456A1 (fr) * | 2019-06-14 | 2020-12-17 | The Trustees Of Columbia University In The City Of New York | Inhibiteurs de nt5c2 pour le traitement de la leucémie lymphoblastique aiguë résistante à la chimiothérapie |
GB202003669D0 (en) * | 2020-03-13 | 2020-04-29 | Univ Oxford Innovation Ltd | Method for identifying neo-antigens |
EP4143345A1 (fr) | 2020-04-28 | 2023-03-08 | Genentech, Inc. | Procédés et compositions pour l'immunothérapie du cancer du poumon non à petites cellules |
WO2022099004A1 (fr) * | 2020-11-06 | 2022-05-12 | The General Hospital Corporation | Procédés pour caractériser des échantillons biologiques |
WO2022235482A1 (fr) * | 2021-05-03 | 2022-11-10 | Rutgers, The State University Of New Jersey | Immunothérapie pour une maladie intestinale inflammatoire et/ou un cancer |
CN113030475B (zh) * | 2021-05-25 | 2021-08-10 | 泛肽生物科技(浙江)有限公司 | 一种基于细胞线粒体质量评估的t细胞pd-1检测方法 |
CN113355424B (zh) * | 2021-07-14 | 2022-03-25 | 江苏先声医学诊断有限公司 | Pcdh11x突变在预测非小细胞肺癌患者对免疫检查点抑制剂疗法敏感性中的应用 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040033497A1 (en) | 2002-08-13 | 2004-02-19 | Alarcon-Riquelme Marta E. | Polymorphisms of PD-1 |
TWI477602B (zh) | 2006-02-09 | 2015-03-21 | Educational Foundation Jichi Medical Univ | Novel viral vector |
CN102713606A (zh) * | 2009-11-13 | 2012-10-03 | 无限制药股份有限公司 | 用于鉴定、评估、预防和治疗癌症的组合物、试剂盒和方法 |
GB201004551D0 (en) * | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
ES2608475T3 (es) * | 2010-04-13 | 2017-04-11 | Celldex Therapeutics, Inc. | Anticuerpos que se unen a cd27 humana y usos de los mismos |
EP2569633B1 (fr) * | 2010-05-14 | 2016-02-10 | The General Hospital Corporation | Compositions et procédés d'identification de néoantigènes spécifiques à une tumeur |
SI2844282T1 (sl) | 2012-05-04 | 2019-08-30 | Pfizer Inc. | S prostato povezani antigeni in na cepljenju osnovan imunoterapevtski režim zdravljenja |
AU2013323368B2 (en) | 2012-09-28 | 2019-03-21 | The University Of Connecticut | Identification of tumor-protective epitopes for the treatment of cancers |
KR20160102314A (ko) * | 2014-01-02 | 2016-08-29 | 메모리얼 슬로안-케터링 캔서 센터 | 면역 치료요법에 대한 암 반응의 결정인자 |
WO2016077553A1 (fr) * | 2014-11-13 | 2016-05-19 | The Johns Hopkins University | Blocage de point de contrôle et instabilité des microsatellites |
MA40737A (fr) | 2014-11-21 | 2017-07-04 | Memorial Sloan Kettering Cancer Center | Déterminants de la réponse d'un cancer à une immunothérapie par blocage de pd-1 |
CA3076894A1 (fr) * | 2017-09-25 | 2019-03-28 | Memorial Sloan Kettering Cancer Center | Fardeau de mutations et immunotherapie des points de controle |
-
2015
- 2015-11-22 MA MA040737A patent/MA40737A/fr unknown
- 2015-11-23 AU AU2015349644A patent/AU2015349644B2/en active Active
- 2015-11-23 CN CN202210026426.9A patent/CN114672559A/zh active Pending
- 2015-11-23 CA CA2968059A patent/CA2968059A1/fr active Pending
- 2015-11-23 CN CN201580073049.2A patent/CN107206064B/zh active Active
- 2015-11-23 US US15/528,385 patent/US20180291074A1/en not_active Abandoned
- 2015-11-23 EP EP15861224.2A patent/EP3220950A4/fr active Pending
- 2015-11-23 JP JP2017527368A patent/JP7173733B2/ja active Active
- 2015-11-23 WO PCT/US2015/062208 patent/WO2016081947A2/fr active Application Filing
-
2018
- 2018-03-21 HK HK18103939.8A patent/HK1244440A1/zh unknown
-
2019
- 2019-02-22 US US16/283,555 patent/US10993998B2/en active Active
-
2020
- 2020-08-11 JP JP2020135853A patent/JP2020196732A/ja not_active Withdrawn
-
2021
- 2021-03-15 US US17/202,173 patent/US20210308241A1/en active Pending
- 2021-08-09 AU AU2021215099A patent/AU2021215099A1/en active Pending
-
2022
- 2022-08-16 JP JP2022129458A patent/JP2023055625A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2020196732A (ja) | 2020-12-10 |
US20200040049A1 (en) | 2020-02-06 |
EP3220950A2 (fr) | 2017-09-27 |
US20180291074A1 (en) | 2018-10-11 |
CN114672559A (zh) | 2022-06-28 |
US10993998B2 (en) | 2021-05-04 |
CN107206064A (zh) | 2017-09-26 |
WO2016081947A3 (fr) | 2016-07-07 |
WO2016081947A4 (fr) | 2016-09-09 |
AU2021215099A1 (en) | 2021-08-26 |
AU2015349644A1 (en) | 2017-06-15 |
EP3220950A4 (fr) | 2018-08-29 |
CN107206064B (zh) | 2021-12-21 |
CA2968059A1 (fr) | 2016-05-26 |
US20210308241A1 (en) | 2021-10-07 |
HK1244440A1 (zh) | 2018-08-10 |
JP7173733B2 (ja) | 2022-11-16 |
AU2015349644B2 (en) | 2021-08-19 |
WO2016081947A2 (fr) | 2016-05-26 |
JP2023055625A (ja) | 2023-04-18 |
JP2018502828A (ja) | 2018-02-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA40737A (fr) | Déterminants de la réponse d'un cancer à une immunothérapie par blocage de pd-1 | |
SG11201605432RA (en) | Determinants of cancer response to immunotherapy | |
MA43258A (fr) | Liants pd1/ctla4 | |
DK3204417T3 (da) | Cd73-blokering | |
DK3186244T3 (da) | Dioxolananaloger af uridin til behandling af cancer | |
DK3148529T3 (da) | Forbindelser til behandling af hjernecancer | |
DK3175012T3 (da) | Forbedret aktivering af selvpassiverende metaller | |
DE112015003457A5 (de) | Al-Gusslegierung | |
HK1250719A1 (zh) | 脫氧糖胺的合成 | |
DK3201559T3 (da) | Patronhylster | |
DK3397352T3 (da) | Antiperspirantsammensætninger | |
DK3253407T3 (da) | Brug af hla-b27-homodimere til kræftbehandling | |
DK3273821T3 (da) | Tilpasseligt smykke | |
HK1258143A1 (zh) | 和厚朴酚的改進的合成 | |
FR3040595B3 (fr) | Parasol suspendu demontable | |
ES1137506Y (es) | Helice reductora de perdidas | |
FR3023260B1 (fr) | Ensemble propulsif d'aeronef | |
KR20180084983A (ko) | 암의 치료를 위한 피리미도-피리미다지논의 용도 | |
EP3516081A4 (fr) | Déterminants de la réponse d'un cancer à l'immunothérapie | |
DK3230300T3 (da) | Inhibitorer til inhibering af tumor metastase | |
MC200163B1 (fr) | Revêtement pour la protection des supports métalliques | |
IT201700081473A1 (it) | Prevenzione mareggiate | |
FI11432U1 (fi) | Kantosuoja | |
IT201700010606A1 (it) | GenialCombi di Moscarelli | |
IT201600129753A1 (it) | Struttura di calcio-balilla |