HUE034832T2 - Anti-PD-L1 antitestek és alkalmazásuk T-sejt-funkció fokozására - Google Patents

Anti-PD-L1 antitestek és alkalmazásuk T-sejt-funkció fokozására

Info

Publication number
HUE034832T2
HUE034832T2 HUE09764997A HUE09764997A HUE034832T2 HU E034832 T2 HUE034832 T2 HU E034832T2 HU E09764997 A HUE09764997 A HU E09764997A HU E09764997 A HUE09764997 A HU E09764997A HU E034832 T2 HUE034832 T2 HU E034832T2
Authority
HU
Hungary
Prior art keywords
antibodies
enhance
cell function
cell
function
Prior art date
Application number
HUE09764997A
Other languages
English (en)
Hungarian (hu)
Inventor
Bryan Irving
Jeanne Cheung
Henry Chiu
Sophie Lehar
Heather Maecker
Sanjeev Mariathasan
Yan Wu
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42097246&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE034832(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HUE034832T2 publication Critical patent/HUE034832T2/hu

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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
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    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61K2039/507Comprising a combination of two or more separate antibodies
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Tropical Medicine & Parasitology (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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HUE09764997A 2008-12-09 2009-12-08 Anti-PD-L1 antitestek és alkalmazásuk T-sejt-funkció fokozására HUE034832T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12109208P 2008-12-09 2008-12-09

Publications (1)

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HUE034832T2 true HUE034832T2 (hu) 2021-12-28

Family

ID=42097246

Family Applications (7)

Application Number Title Priority Date Filing Date
HUE23214687A HUE070712T2 (hu) 2008-12-09 2009-12-08 ANTI-PD-L1 ellenanyagok és alkalmazásuk T-sejt funkció fokozására
HUE09764997A HUE034832T2 (hu) 2008-12-09 2009-12-08 Anti-PD-L1 antitestek és alkalmazásuk T-sejt-funkció fokozására
HUE22215991A HUE065752T2 (hu) 2008-12-09 2009-12-08 Anti-PD-L1 antitestek és felhasználásuk T-sejt funkció elõsegítésére
HUS1700049C HUS1700049I1 (hu) 2008-12-09 2017-11-28 Anti-PD-L1 antitestek és alkalmazásuk T-sejt-funkció fokozására
HUS2400018C HUS2400018I1 (hu) 2008-12-09 2024-06-11 Anti-PD-L1 antitestek és felhasználásuk T-sejt funkció elõsegítésére
HUS2400020C HUS2400020I1 (hu) 2008-12-09 2024-06-12 Anti-PD-L1 antitestek és felhasználásuk T-sejt funkció elõsegítésére
HUS2500027C HUS2500027I1 (hu) 2008-12-09 2025-06-18 ANTI-PD-L1 ellenanyagok és alkalmazásuk T-sejt funkció fokozására

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE23214687A HUE070712T2 (hu) 2008-12-09 2009-12-08 ANTI-PD-L1 ellenanyagok és alkalmazásuk T-sejt funkció fokozására

Family Applications After (5)

Application Number Title Priority Date Filing Date
HUE22215991A HUE065752T2 (hu) 2008-12-09 2009-12-08 Anti-PD-L1 antitestek és felhasználásuk T-sejt funkció elõsegítésére
HUS1700049C HUS1700049I1 (hu) 2008-12-09 2017-11-28 Anti-PD-L1 antitestek és alkalmazásuk T-sejt-funkció fokozására
HUS2400018C HUS2400018I1 (hu) 2008-12-09 2024-06-11 Anti-PD-L1 antitestek és felhasználásuk T-sejt funkció elõsegítésére
HUS2400020C HUS2400020I1 (hu) 2008-12-09 2024-06-12 Anti-PD-L1 antitestek és felhasználásuk T-sejt funkció elõsegítésére
HUS2500027C HUS2500027I1 (hu) 2008-12-09 2025-06-18 ANTI-PD-L1 ellenanyagok és alkalmazásuk T-sejt funkció fokozására

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US (12) US8217149B2 (enExample)
EP (8) EP2376535B9 (enExample)
JP (6) JP5681638B2 (enExample)
KR (10) KR20200047793A (enExample)
CN (4) CN108997498A (enExample)
AR (2) AR074563A1 (enExample)
AU (5) AU2009333580B2 (enExample)
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FR (3) FR17C1050I2 (enExample)
HK (1) HK1247621A1 (enExample)
HR (3) HRP20250296T1 (enExample)
HU (7) HUE070712T2 (enExample)
IL (4) IL213353A (enExample)
LT (6) LT4331604T (enExample)
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MA (1) MA32948B1 (enExample)
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DE602004028930D1 (de) 2003-04-29 2010-10-14 Avi Biopharma Inc Zusammensetzungen zur verbesserung der antisense-wirksamkeit und des transports von nukleinsäureanalog in zellen
US8067571B2 (en) 2005-07-13 2011-11-29 Avi Biopharma, Inc. Antibacterial antisense oligonucleotide and method
US20100016215A1 (en) 2007-06-29 2010-01-21 Avi Biopharma, Inc. Compound and method for treating myotonic dystrophy
US9090894B2 (en) * 2007-12-17 2015-07-28 California Institute Of Technology Modulating immune system development and function through microRNA MIR-146
EP3153526B1 (en) 2008-01-31 2020-09-23 INSERM - Institut National de la Santé et de la Recherche Médicale Antibodies against human cd39 and use thereof for inhibiting t regulatory cells activity
EP2257301B1 (en) 2008-03-03 2014-01-22 The University of Miami Allogeneic cancer cell-based immunotherapy
ES2758126T3 (es) 2008-04-09 2020-05-04 Genentech Inc Composiciones y métodos para el tratamiento de enfermedades relacionadas con la inmunidad
US9650639B2 (en) 2008-05-19 2017-05-16 Advaxis, Inc. Dual delivery system for heterologous antigens
US9017660B2 (en) 2009-11-11 2015-04-28 Advaxis, Inc. Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors
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