JP5681638B2 - 抗ｐｄ−ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用 - Google Patents

抗ｐｄ−ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用 Download PDF

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JP5681638B2
JP5681638B2 JP2011540819A JP2011540819A JP5681638B2 JP 5681638 B2 JP5681638 B2 JP 5681638B2 JP 2011540819 A JP2011540819 A JP 2011540819A JP 2011540819 A JP2011540819 A JP 2011540819A JP 5681638 B2 JP5681638 B2 JP 5681638B2
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antibody
cells
hvr
cell
seq
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JP2012511329A5 (enExample
JP2012511329A (ja
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アーヴィング，ブライアン
チャン，ジャンヌ
チウ，ヘンリー
レハー，ソフィー・エム
メッカー，ヘザー
マリアタサン，サンジーヴ
ウー，ヤン
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Genentech Inc
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Genentech Inc
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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JP2011540819A 2008-12-09 2009-12-08 抗ｐｄ−ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用 Active JP5681638B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12109208P 2008-12-09 2008-12-09
US61/121,092 2008-12-09
PCT/US2009/067104 WO2010077634A1 (en) 2008-12-09 2009-12-08 Anti-pd-l1 antibodies and their use to enhance t-cell function

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JP2015003298A Division JP6178349B2 (ja) 2008-12-09 2015-01-09 抗ｐｄ−ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用

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JP2012511329A JP2012511329A (ja) 2012-05-24
JP2012511329A5 JP2012511329A5 (enExample) 2014-03-13
JP5681638B2 true JP5681638B2 (ja) 2015-03-11

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JP2011540819A Active JP5681638B2 (ja) 2008-12-09 2009-12-08 抗ｐｄ−ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用
JP2015003298A Active JP6178349B2 (ja) 2008-12-09 2015-01-09 抗ｐｄ−ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用
JP2017075787A Active JP6509935B2 (ja) 2008-12-09 2017-04-06 抗ｐｄ−ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用
JP2019071460A Pending JP2019122409A (ja) 2008-12-09 2019-04-03 抗ｐｄ−ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用
JP2021196323A Active JP7332671B2 (ja) 2008-12-09 2021-12-02 抗ｐｄ－ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用
JP2023131222A Pending JP2023154034A (ja) 2008-12-09 2023-08-10 抗ｐｄ－ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用

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JP2017075787A Active JP6509935B2 (ja) 2008-12-09 2017-04-06 抗ｐｄ−ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用
JP2019071460A Pending JP2019122409A (ja) 2008-12-09 2019-04-03 抗ｐｄ−ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用
JP2021196323A Active JP7332671B2 (ja) 2008-12-09 2021-12-02 抗ｐｄ－ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用
JP2023131222A Pending JP2023154034A (ja) 2008-12-09 2023-08-10 抗ｐｄ－ｌ１抗体およびｔ細胞機能を増強するためのそれらの使用

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