HK1206601A1 - Modified polynucleotides for the production of biologics and proteins associated with human disease - Google Patents

Modified polynucleotides for the production of biologics and proteins associated with human disease

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Publication number
HK1206601A1
HK1206601A1 HK15107125.6A HK15107125A HK1206601A1 HK 1206601 A1 HK1206601 A1 HK 1206601A1 HK 15107125 A HK15107125 A HK 15107125A HK 1206601 A1 HK1206601 A1 HK 1206601A1
Authority
HK
Hong Kong
Prior art keywords
biologics
production
human disease
proteins associated
modified polynucleotides
Prior art date
Application number
HK15107125.6A
Other languages
English (en)
Chinese (zh)
Inventor
Stephane Bancel
Tirtha Chakraborty
Fougerolles Antonin De
Sayda M Elbashir
Matthias John
Atanu Roy
Susan Whoriskey
Kristy M Wood
Paul Hatala
Jason P Schrum
Kenechi Ejebe
Jeff Lynn Ellsworth
Justin Guild
Original Assignee
Moderna Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49235350&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1206601(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/US2013/030062 external-priority patent/WO2013151666A2/en
Application filed by Moderna Therapeutics Inc filed Critical Moderna Therapeutics Inc
Publication of HK1206601A1 publication Critical patent/HK1206601A1/xx

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    • A61K48/0066Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
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    • A61K31/7115Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
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