MX2010002113A - Metodos para detectar oligonucleotidos. - Google Patents
Metodos para detectar oligonucleotidos.Info
- Publication number
- MX2010002113A MX2010002113A MX2010002113A MX2010002113A MX2010002113A MX 2010002113 A MX2010002113 A MX 2010002113A MX 2010002113 A MX2010002113 A MX 2010002113A MX 2010002113 A MX2010002113 A MX 2010002113A MX 2010002113 A MX2010002113 A MX 2010002113A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- oligonucleotides
- detecting
- compositions
- detecting oligonucleotides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/204—Modifications characterised by specific length of the oligonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La invención proporciona métodos y composiciones para detectar y/o cuantificar oligonucleótidos de ácidos nucleicos. Estos métodos y composiciones son útiles para detectar y cuantificar los oligonucleótidos objetivo sintéticos de diagnóstico y/o terapéuticos, tales como aptámeros, ARNi, siARN, oligonucleótidos anti-sentido, ó ribozimas en una muestra biológica.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95748707P | 2007-08-23 | 2007-08-23 | |
PCT/EP2008/060948 WO2009024599A1 (en) | 2007-08-23 | 2008-08-21 | Methods for detecting oligonucleotides |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010002113A true MX2010002113A (es) | 2010-03-26 |
Family
ID=40076846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010002113A MX2010002113A (es) | 2007-08-23 | 2008-08-21 | Metodos para detectar oligonucleotidos. |
Country Status (9)
Country | Link |
---|---|
US (1) | US20110097716A1 (es) |
EP (1) | EP2183390A1 (es) |
KR (1) | KR20100063079A (es) |
CN (1) | CN101835903A (es) |
AU (1) | AU2008290545A1 (es) |
BR (1) | BRPI0815725A2 (es) |
CA (1) | CA2695420A1 (es) |
MX (1) | MX2010002113A (es) |
WO (1) | WO2009024599A1 (es) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2600901B1 (en) | 2010-08-06 | 2019-03-27 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
ES2737960T3 (es) | 2010-10-01 | 2020-01-17 | Modernatx Inc | Nucleósidos, nucleótidos y ácidos nucleicos modificados y sus usos |
AU2012236099A1 (en) | 2011-03-31 | 2013-10-03 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
WO2012149042A2 (en) | 2011-04-25 | 2012-11-01 | Bio-Rad Laboratories, Inc. | Methods and compositions for nucleic acid analysis |
TR201910686T4 (tr) | 2011-06-08 | 2019-08-21 | Translate Bio Inc | Mrna iletimine yönelik lipit nanopartikül bileşimleri ve yöntemler. |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
EP3682905B1 (en) | 2011-10-03 | 2021-12-01 | ModernaTX, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
EP2791160B1 (en) | 2011-12-16 | 2022-03-02 | ModernaTX, Inc. | Modified mrna compositions |
EP2802674B1 (en) | 2012-01-11 | 2020-12-16 | Ionis Pharmaceuticals, Inc. | Compositions and methods for modulation of ikbkap splicing |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
US9303079B2 (en) | 2012-04-02 | 2016-04-05 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
AU2013243948A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins associated with human disease |
EP4074834A1 (en) | 2012-11-26 | 2022-10-19 | ModernaTX, Inc. | Terminally modified rna |
WO2014137329A1 (en) | 2013-03-05 | 2014-09-12 | Agilent Technologies, Inc. | Synthesis of pools of probes by primer extension |
WO2014145620A2 (en) * | 2013-03-15 | 2014-09-18 | The Broad Institute, Inc. | Novel hybridization probes and uses thereof |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
WO2015048744A2 (en) | 2013-09-30 | 2015-04-02 | Moderna Therapeutics, Inc. | Polynucleotides encoding immune modulating polypeptides |
CA2926218A1 (en) | 2013-10-03 | 2015-04-09 | Moderna Therapeutics, Inc. | Polynucleotides encoding low density lipoprotein receptor |
US11162096B2 (en) * | 2013-10-14 | 2021-11-02 | Ionis Pharmaceuticals, Inc | Methods for modulating expression of C9ORF72 antisense transcript |
EP3334499A4 (en) * | 2015-08-14 | 2019-04-17 | University of Massachusetts | BIOACTIVE CONJUGATES FOR THE RELEASE OF OLIGONUCLEOTIDES |
PT3350157T (pt) | 2015-09-17 | 2022-03-18 | Modernatx Inc | Compostos e composições para administração intracelular de agentes terapêuticos |
EP3964200A1 (en) | 2015-12-10 | 2022-03-09 | ModernaTX, Inc. | Compositions and methods for delivery of therapeutic agents |
AU2016377681B2 (en) | 2015-12-22 | 2021-05-13 | Modernatx, Inc. | Compounds and compositions for intracellular delivery of agents |
US9617587B1 (en) * | 2016-04-04 | 2017-04-11 | Nat Diagnostics, Inc. | Isothermal amplification components and processes |
CA3039068A1 (en) * | 2016-10-07 | 2018-04-12 | Secarna Pharmaceuticals Gmbh & Co. Kg | Immunosuppression-reverting oligonucleotides inhibiting the expression of cd39 |
WO2018089540A1 (en) | 2016-11-08 | 2018-05-17 | Modernatx, Inc. | Stabilized formulations of lipid nanoparticles |
US11085071B2 (en) * | 2017-02-01 | 2021-08-10 | Spot Biosystems Ltd. | Highly stable and specific molecular beacons encapsulated in cationic lipoplex nanoparticles and application thereof |
ES2911186T3 (es) | 2017-03-15 | 2022-05-18 | Modernatx Inc | Formas cristalinas de aminolípidos |
PL3596041T3 (pl) | 2017-03-15 | 2023-03-06 | Modernatx, Inc. | Związek i kompozycje do dokomórkowego dostarczania środków terapeutycznych |
US11969506B2 (en) | 2017-03-15 | 2024-04-30 | Modernatx, Inc. | Lipid nanoparticle formulation |
US11786607B2 (en) | 2017-06-15 | 2023-10-17 | Modernatx, Inc. | RNA formulations |
WO2019046809A1 (en) | 2017-08-31 | 2019-03-07 | Modernatx, Inc. | METHODS OF MANUFACTURING LIPID NANOPARTICLES |
EP3906317A1 (en) * | 2019-01-03 | 2021-11-10 | DNA Script | One pot synthesis of sets of oligonucleotides |
CN109913534A (zh) * | 2019-01-24 | 2019-06-21 | 中国药科大学 | 一种基于级联DNA链循环反应和荧光共振能量转移效应的两种miRNA同时检测的方法 |
CN109868309B (zh) * | 2019-03-05 | 2022-11-11 | 苏州恩可医药科技有限公司 | 基于通用碱基替换插入的单链dna扩增方法 |
AR120080A1 (es) | 2019-09-19 | 2022-02-02 | Modernatx Inc | Compuestos lipídicos de cola ramificada y composiciones para la administración intracelular de agentes terapéuticos |
CN111500676B (zh) * | 2020-04-21 | 2022-09-09 | 桂林旅游学院 | 一种将寡聚核苷酸逆转录成cDNA的方法及寡聚核苷酸检测方法 |
US11524023B2 (en) | 2021-02-19 | 2022-12-13 | Modernatx, Inc. | Lipid nanoparticle compositions and methods of formulating the same |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7575863B2 (en) * | 2004-05-28 | 2009-08-18 | Applied Biosystems, Llc | Methods, compositions, and kits comprising linker probes for quantifying polynucleotides |
US20060057595A1 (en) * | 2004-09-16 | 2006-03-16 | Applera Corporation | Compositions, methods, and kits for identifying and quantitating small RNA molecules |
DE602006016739D1 (de) * | 2005-01-25 | 2010-10-21 | Rosetta Inpharmatics Llc | Verfahren zur quantifizierung kleiner rna-moleküle |
-
2008
- 2008-08-21 EP EP08787390A patent/EP2183390A1/en not_active Withdrawn
- 2008-08-21 WO PCT/EP2008/060948 patent/WO2009024599A1/en active Application Filing
- 2008-08-21 BR BRPI0815725-1A2A patent/BRPI0815725A2/pt not_active Application Discontinuation
- 2008-08-21 CA CA2695420A patent/CA2695420A1/en not_active Abandoned
- 2008-08-21 CN CN200880112769A patent/CN101835903A/zh active Pending
- 2008-08-21 KR KR1020107006245A patent/KR20100063079A/ko not_active Application Discontinuation
- 2008-08-21 MX MX2010002113A patent/MX2010002113A/es not_active Application Discontinuation
- 2008-08-21 AU AU2008290545A patent/AU2008290545A1/en not_active Abandoned
-
2009
- 2009-08-21 US US12/674,639 patent/US20110097716A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20110097716A1 (en) | 2011-04-28 |
EP2183390A1 (en) | 2010-05-12 |
BRPI0815725A2 (pt) | 2015-02-10 |
CN101835903A (zh) | 2010-09-15 |
CA2695420A1 (en) | 2009-02-26 |
WO2009024599A1 (en) | 2009-02-26 |
AU2008290545A1 (en) | 2009-02-26 |
KR20100063079A (ko) | 2010-06-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |