EP2126122A4 - Method and test kit for determining the amounts of target sequences and nucleotide variations therein - Google Patents

Method and test kit for determining the amounts of target sequences and nucleotide variations therein

Info

Publication number
EP2126122A4
EP2126122A4 EP08718527A EP08718527A EP2126122A4 EP 2126122 A4 EP2126122 A4 EP 2126122A4 EP 08718527 A EP08718527 A EP 08718527A EP 08718527 A EP08718527 A EP 08718527A EP 2126122 A4 EP2126122 A4 EP 2126122A4
Authority
EP
European Patent Office
Prior art keywords
amounts
determining
test kit
target sequences
nucleotide variations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08718527A
Other languages
German (de)
French (fr)
Other versions
EP2126122A1 (en
Inventor
Hans Soederlund
Jari Rautio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valtion Teknillinen Tutkimuskeskus
Original Assignee
Valtion Teknillinen Tutkimuskeskus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valtion Teknillinen Tutkimuskeskus filed Critical Valtion Teknillinen Tutkimuskeskus
Publication of EP2126122A1 publication Critical patent/EP2126122A1/en
Publication of EP2126122A4 publication Critical patent/EP2126122A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP08718527A 2007-02-21 2008-02-20 Method and test kit for determining the amounts of target sequences and nucleotide variations therein Withdrawn EP2126122A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20075124A FI20075124A0 (en) 2007-02-21 2007-02-21 Method and test kit for detection of nucleotide variations
PCT/FI2008/050074 WO2008102057A1 (en) 2007-02-21 2008-02-20 Method and test kit for determining the amounts of target sequences and nucleotide variations therein

Publications (2)

Publication Number Publication Date
EP2126122A1 EP2126122A1 (en) 2009-12-02
EP2126122A4 true EP2126122A4 (en) 2010-11-10

Family

ID=37832273

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08718527A Withdrawn EP2126122A4 (en) 2007-02-21 2008-02-20 Method and test kit for determining the amounts of target sequences and nucleotide variations therein

Country Status (6)

Country Link
EP (1) EP2126122A4 (en)
JP (1) JP2010518846A (en)
AU (1) AU2008217678B9 (en)
CA (1) CA2678693A1 (en)
FI (1) FI20075124A0 (en)
WO (1) WO2008102057A1 (en)

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US20110218123A1 (en) 2008-09-19 2011-09-08 President And Fellows Of Harvard College Creation of libraries of droplets and related species
US8748094B2 (en) 2008-12-19 2014-06-10 President And Fellows Of Harvard College Particle-assisted nucleic acid sequencing
US9056289B2 (en) 2009-10-27 2015-06-16 President And Fellows Of Harvard College Droplet creation techniques
MX352460B (en) 2011-01-11 2017-11-24 Seegene Inc Detection of target nucleic acid sequences by pto cleavage and extension assay.
CN103534358B (en) 2011-03-29 2015-03-25 Seegene株式会社 Detection of target nucleic acid sequence by PTO cleavage and extension-dependent cleavage
US9850524B2 (en) 2011-05-04 2017-12-26 Seegene, Inc. Detection of target nucleic acid sequences by PO cleavage and hybridization
KR20130101952A (en) 2012-02-02 2013-09-16 주식회사 씨젠 Detection of target nucleic acid sequence by pto cleavage and extension-dependent hybridization
WO2013133561A1 (en) * 2012-03-05 2013-09-12 Seegene, Inc. Detection of nucleotide variation on target nucleic acid sequence by pto cleavage and extension assay
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10221442B2 (en) 2012-08-14 2019-03-05 10X Genomics, Inc. Compositions and methods for sample processing
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10400280B2 (en) 2012-08-14 2019-09-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
MX364957B (en) 2012-08-14 2019-05-15 10X Genomics Inc Microcapsule compositions and methods.
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
CA2894694C (en) 2012-12-14 2023-04-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
CN105102697A (en) 2013-02-08 2015-11-25 10X基因组学有限公司 Polynucleotide barcode generation
EP2770065B1 (en) 2013-02-25 2017-12-13 Seegene, Inc. Detection of nucleotide variation on target nucleic acid sequence
US10395758B2 (en) 2013-08-30 2019-08-27 10X Genomics, Inc. Sequencing methods
US20160279068A1 (en) 2013-11-08 2016-09-29 President And Fellows Of Harvard College Microparticles, methods for their preparation and use
US9824068B2 (en) 2013-12-16 2017-11-21 10X Genomics, Inc. Methods and apparatus for sorting data
KR102596508B1 (en) 2014-04-10 2023-10-30 10엑스 제노믹스, 인크. Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same
AU2015279546B2 (en) 2014-06-26 2021-04-08 10X Genomics, Inc. Processes and systems for nucleic acid sequence assembly
JP6838969B2 (en) 2014-06-26 2021-03-03 １０エックス ジェノミクス， インコーポレイテッド Method for Analyzing Nucleic Acids Derived from Individual Cells or Cell Populations
AU2015339148B2 (en) 2014-10-29 2022-03-10 10X Genomics, Inc. Methods and compositions for targeted nucleic acid sequencing
US9975122B2 (en) 2014-11-05 2018-05-22 10X Genomics, Inc. Instrument systems for integrated sample processing
MX367432B (en) 2015-01-12 2019-08-08 10X Genomics Inc Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same.
CN107209814B (en) 2015-01-13 2021-10-15 10X基因组学有限公司 System and method for visualizing structural variation and phase information
EP3256606B1 (en) 2015-02-09 2019-05-22 10X Genomics, Inc. Systems and methods for determining structural variation
EP3259356B1 (en) * 2015-02-20 2021-12-01 Rosalind Franklin University of Medicine and Science Antisense compounds targeting genes associated with cystic fibrosis
US10525076B2 (en) 2015-02-20 2020-01-07 Rosalind Franklin University Of Medicine And Science Antisense compounds targeting genes associated with cystic fibrosis
WO2016137973A1 (en) 2015-02-24 2016-09-01 10X Genomics Inc Partition processing methods and systems
CN107532202A (en) 2015-02-24 2018-01-02 10X 基因组学有限公司 Method for targetting nucleotide sequence covering
JP2018537414A (en) 2015-10-13 2018-12-20 プレジデント アンド フェローズ オブ ハーバード カレッジ System and method for making and using gel microspheres
ES2926495T3 (en) 2015-12-04 2022-10-26 10X Genomics Inc Methods and compositions for nucleic acid analysis
CN107024583B (en) * 2016-01-29 2019-03-08 中国科学院苏州纳米技术与纳米仿生研究所 Thioflavine T aptamers, its screening technique and application
SG11201806757XA (en) 2016-02-11 2018-09-27 10X Genomics Inc Systems, methods, and media for de novo assembly of whole genome sequence data
WO2017197338A1 (en) 2016-05-13 2017-11-16 10X Genomics, Inc. Microfluidic systems and methods of use
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
CN110214186B (en) 2017-01-30 2023-11-24 10X基因组学有限公司 Method and system for droplet-based single cell bar coding
CN110870018A (en) 2017-05-19 2020-03-06 10X基因组学有限公司 System and method for analyzing a data set
US10400235B2 (en) 2017-05-26 2019-09-03 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
CN116064732A (en) 2017-05-26 2023-05-05 10X基因组学有限公司 Single cell analysis of transposase accessibility chromatin
EP3688188A4 (en) 2017-09-29 2021-06-16 Seegene, Inc. Detection of target nucleic acid sequences by pto cleavage and extension-dependent extension assay
EP3625361A1 (en) 2017-11-15 2020-03-25 10X Genomics, Inc. Functionalized gel beads
US10829815B2 (en) 2017-11-17 2020-11-10 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
EP3775271A1 (en) 2018-04-06 2021-02-17 10X Genomics, Inc. Systems and methods for quality control in single cell processing
JP2024515244A (en) * 2021-04-07 2024-04-08 ユニバーシティ オブ マサチューセッツ Programmed read-through of nonsense codons by specific oligonucleotides

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1101824A2 (en) * 1999-11-22 2001-05-23 Xiao Bing Wang Detection of sequence variation of nucleic acid by shifted termination analysis
US20060035228A1 (en) * 2002-07-05 2006-02-16 Hans Soderlund Method and test kit for quantitative determination of polynucleotides in a mixture

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BR9206705A (en) * 1991-11-01 1995-11-21 Adelaide Children S Hospital Solid phase amplification process
JP2775346B2 (en) * 1992-04-03 1998-07-16 アプライド バイオシステムズ，インコーポレイテッド Probe composition and method
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AU1623899A (en) * 1997-12-04 1999-06-16 Packard Bioscience Company Methods of using probes for analyzing polynucleotide sequence
US6635419B1 (en) * 1999-02-16 2003-10-21 Applera Corporation Polynucleotide sequencing method
US6537755B1 (en) * 1999-03-25 2003-03-25 Radoje T. Drmanac Solution-based methods and materials for sequence analysis by hybridization
FI115139B (en) * 2001-01-10 2005-03-15 Valtion Teknillinen Method and test package for quantitative and / or comparative assessment of the variations of polynucleotide amounts in cell or tissue samples
US20030077584A1 (en) * 2001-08-28 2003-04-24 Mark Kunkel Methods and compositons for bi-directional polymorphism detection
JP3752466B2 (en) * 2002-04-24 2006-03-08 株式会社日立製作所 Genetic testing method
JP4617403B2 (en) * 2002-06-28 2011-01-26 プリメラディーエックス インコーポレイテッド How to detect sequence differences

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1101824A2 (en) * 1999-11-22 2001-05-23 Xiao Bing Wang Detection of sequence variation of nucleic acid by shifted termination analysis
US20060035228A1 (en) * 2002-07-05 2006-02-16 Hans Soderlund Method and test kit for quantitative determination of polynucleotides in a mixture

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2008102057A1 *

Also Published As

Publication number Publication date
JP2010518846A (en) 2010-06-03
WO2008102057A1 (en) 2008-08-28
EP2126122A1 (en) 2009-12-02
AU2008217678A1 (en) 2008-08-28
WO2008102057A9 (en) 2008-10-09
CA2678693A1 (en) 2008-08-28
AU2008217678B2 (en) 2013-09-12
FI20075124A0 (en) 2007-02-21
AU2008217678B9 (en) 2013-10-03

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