ATE427992T1 - Dna-synthesepromotoren, mit dna-polymerase assoziierte faktoren und nutzung davon - Google Patents

Dna-synthesepromotoren, mit dna-polymerase assoziierte faktoren und nutzung davon

Info

Publication number
ATE427992T1
ATE427992T1 AT02780096T AT02780096T ATE427992T1 AT E427992 T1 ATE427992 T1 AT E427992T1 AT 02780096 T AT02780096 T AT 02780096T AT 02780096 T AT02780096 T AT 02780096T AT E427992 T1 ATE427992 T1 AT E427992T1
Authority
AT
Austria
Prior art keywords
dna
dna synthesis
dna polymerase
synthesis
integer
Prior art date
Application number
AT02780096T
Other languages
English (en)
Inventor
Masao Kitabayashi
Toshihiro Kuroita
Yoshikazu Ishida
Hideyuki Komatsubara
Yoshiaki Nishiya
Masanori Oka
Yoshihisa Kawamura
Tadayuki Imanaka
Original Assignee
Toyo Boseki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2001349173A external-priority patent/JP2003144169A/ja
Priority claimed from JP2002311596A external-priority patent/JP4300321B2/ja
Application filed by Toyo Boseki filed Critical Toyo Boseki
Application granted granted Critical
Publication of ATE427992T1 publication Critical patent/ATE427992T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6846—Common amplification features

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
AT02780096T 2001-11-14 2002-11-14 Dna-synthesepromotoren, mit dna-polymerase assoziierte faktoren und nutzung davon ATE427992T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001349173A JP2003144169A (ja) 2001-11-14 2001-11-14 Ｄｎａ合成反応を促進する添加剤
JP2002311596A JP4300321B2 (ja) 2002-10-25 2002-10-25 Ｄｎａ合成反応を促進する方法、およびそのための組成物

Publications (1)

Publication Number Publication Date
ATE427992T1 true ATE427992T1 (de) 2009-04-15

Family

ID=26624518

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02780096T ATE427992T1 (de) 2001-11-14 2002-11-14 Dna-synthesepromotoren, mit dna-polymerase assoziierte faktoren und nutzung davon

Country Status (5)

Country Link
US (1) US7384739B2 (de)
EP (1) EP1452593B1 (de)
AT (1) ATE427992T1 (de)
DE (1) DE60231901D1 (de)
WO (1) WO2003042383A1 (de)

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CA2568998A1 (en) * 2004-06-04 2005-12-15 Takara Bio Inc. Polypeptides having dna polymerase activity
JP4719455B2 (ja) * 2004-12-07 2011-07-06 シスメックス株式会社 直接核酸増幅方法用生体試料処理液および直接核酸増幅方法
EP1918370B1 (de) * 2005-07-04 2014-04-16 Celestar Lexico-Sciences, Inc. Pcna-mutante
US9090948B2 (en) * 2008-09-30 2015-07-28 Abbott Molecular Inc. Primers and probes for detecting human papillomavirus and human beta globin sequences in test samples
CN102803956A (zh) * 2009-06-12 2012-11-28 纳内克蒂斯生物技术公司 用于检测在aids患者的抗逆转录病毒疗法后剩余的病毒hiv dna的高灵敏方法
WO2010147111A1 (ja) 2009-06-15 2010-12-23 トヨタ自動車株式会社 無細胞タンパク質合成溶液、無細胞タンパク質合成キット及びタンパク質合成方法
CA2807552A1 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
SMT202200321T1 (it) 2010-10-01 2022-09-14 Modernatx Inc Acidi ribonucleici contenenti n1-metil-pseudouracili e loro usi
DE12722942T1 (de) 2011-03-31 2021-09-30 Modernatx, Inc. Freisetzung und formulierung von manipulierten nukleinsäuren
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
JP6113737B2 (ja) 2011-10-03 2017-04-12 モデルナティエックス インコーポレイテッドＭｏｄｅｒｎａＴＸ，Ｉｎｃ． 修飾型のヌクレオシド、ヌクレオチドおよび核酸、ならびにそれらの使用方法
CA3018046A1 (en) 2011-12-16 2013-06-20 Moderna Therapeutics, Inc. Modified nucleoside, nucleotide, and nucleic acid compositions
US9689013B2 (en) 2012-01-31 2017-06-27 Takara Bio Inc. Method for improving nucleic acid synthesis reaction
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US10501512B2 (en) 2012-04-02 2019-12-10 Modernatx, Inc. Modified polynucleotides
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
JP2015513913A (ja) 2012-04-02 2015-05-18 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 修飾ポリヌクレオチド
JP6478446B2 (ja) * 2012-09-28 2019-03-06 東洋紡株式会社 改変された耐熱性ｄｎａポリメラーゼ
US10087491B2 (en) * 2012-10-22 2018-10-02 Bayer Cropscience Nv Methods, compositions and devices for amplification of nucleic acids
ES2921623T3 (es) 2012-11-26 2022-08-30 Modernatx Inc ARN modificado terminalmente
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
CA2923029A1 (en) 2013-09-03 2015-03-12 Moderna Therapeutics, Inc. Chimeric polynucleotides
MX2016004249A (es) 2013-10-03 2016-11-08 Moderna Therapeutics Inc Polinulcleotidos que codifican el receptor de lipoproteina de baja densidad.
EP4159741A1 (de) 2014-07-16 2023-04-05 ModernaTX, Inc. Verfahren zur herstellung eines chimären polynukleotids zur kodierung eines polypeptids mit einer triazolhaltigen internukleotid-bindung
EP3247804B1 (de) * 2015-01-23 2020-08-05 Qiagen Sciences, LLC Hochmultiplex-pcr mit molekularer strichcodierung
EP3394093B1 (de) 2015-12-23 2022-01-26 Modernatx, Inc. Verfahren zur verwendung von ox40-ligand-codierenden polynukleotiden
MA43587A (fr) 2016-01-10 2018-11-14 Modernatx Inc Arnm thérapeutiques codant pour des anticorps anti-ctla-4
US10323243B2 (en) 2016-01-19 2019-06-18 Board Of Regents, The University Of Texas System Thermostable reverse transcriptase
PL3458474T3 (pl) 2016-05-18 2022-11-14 Modernatx, Inc. Kombinacje mrna kodujących polipeptydy immunomodulujące i ich zastosowania
KR20220159479A (ko) 2016-05-18 2022-12-02 모더나티엑스, 인크. 인터류킨-12 (il12)를 코딩하는 폴리뉴클레오티드 및 그의 용도
US20200131498A1 (en) 2017-06-14 2020-04-30 Modernatx, Inc. Polynucleotides encoding methylmalonyl-coa mutase
WO2019084538A1 (en) 2017-10-27 2019-05-02 Board Of Regents, The University Of Texas System TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF

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US5284940A (en) * 1990-11-14 1994-02-08 Hri Research, Inc. Preparation for nucleic acid samples
EP0742838B1 (de) 1994-01-31 2003-08-13 The Regents Of The University Of California Methode zur eliminierung von sequenzierartefakten
DE4411588C1 (de) 1994-03-30 1995-09-28 Deutsches Rheuma Forschungszen Puffer für DNA- und RNA-Polymerase-Reaktionen
US5556771A (en) 1995-02-10 1996-09-17 Gen-Probe Incorporated Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification
FR2733515B1 (fr) 1995-04-27 1997-09-05 Cis Bio Int Tampon, procede et methode d'evaluation des conditions optimales, d'amplification de sequences cibles d'acide nucleique, et leurs applications
JP3112148B2 (ja) 1995-05-31 2000-11-27 東洋紡績株式会社 核酸の増幅方法およびその試薬
US5773258A (en) * 1995-08-25 1998-06-30 Roche Molecular Systems, Inc. Nucleic acid amplification using a reversibly inactivated thermostable enzyme
US6114150A (en) * 1995-11-29 2000-09-05 Yale University Amplification of nucleic acids
CA2241170A1 (en) 1995-12-27 1997-07-10 Takara Shuzo Co., Ltd. Novel dna polymerase
EP0834569A1 (de) * 1996-10-03 1998-04-08 Roche Diagnostics GmbH Thermostabile DNS Polymerase aus Carboxydothermus hydrogenoformans
WO1998045452A2 (en) 1997-04-08 1998-10-15 The Rockfeller University Enzyme derived from thermophilic organisms that functions as a chromosomal replicase, and preparation and uses thereof
CN1183253C (zh) 1997-06-26 2005-01-05 宝生物工程株式会社 Dna聚合酶相关因子
US6787305B1 (en) 1998-03-13 2004-09-07 Invitrogen Corporation Compositions and methods for enhanced synthesis of nucleic acid molecules
AU6385800A (en) * 1999-07-30 2001-02-19 Stratagene Archaeal replication accessory factors and methods of use
DE19937230A1 (de) 1999-08-06 2001-02-08 Lion Bioscience Ag Chimäre Proteine

Also Published As

Publication number Publication date
DE60231901D1 (de) 2009-05-20
US20050069887A1 (en) 2005-03-31
WO2003042383A1 (en) 2003-05-22
EP1452593A4 (de) 2005-11-30
EP1452593A1 (de) 2004-09-01
US7384739B2 (en) 2008-06-10
EP1452593B1 (de) 2009-04-08

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