US5563250A
(en)
|
1987-12-02 |
1996-10-08 |
Neorx Corporation |
Cleavable conjugates for the delivery and release of agents in native form
|
US6140496A
(en)
|
1990-10-09 |
2000-10-31 |
Benner; Steven Albert |
Precursors for deoxyribonucleotides containing non-standard nucleosides
|
US5505931A
(en)
|
1993-03-04 |
1996-04-09 |
The Dow Chemical Company |
Acid cleavable compounds, their preparation and use as bifunctional acid-labile crosslinking agents
|
US5681702A
(en)
|
1994-08-30 |
1997-10-28 |
Chiron Corporation |
Reduction of nonspecific hybridization by using novel base-pairing schemes
|
US5585108A
(en)
|
1994-12-30 |
1996-12-17 |
Nanosystems L.L.C. |
Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
US6265389B1
(en)
|
1995-08-31 |
2001-07-24 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of oligonucleotides
|
US6630351B1
(en)
|
1999-06-07 |
2003-10-07 |
Mirus Corporation |
Compositions and methods for drug delivery using pH sensitive molecules
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
US20030073640A1
(en)
|
1997-07-23 |
2003-04-17 |
Ribozyme Pharmaceuticals, Inc. |
Novel compositions for the delivery of negatively charged molecules
|
US6426086B1
(en)
|
1998-02-03 |
2002-07-30 |
The Regents Of The University Of California |
pH-sensitive, serum-stable liposomes
|
EP1816197B1
(fr)
|
1998-04-23 |
2009-09-16 |
Takara Bio Inc. |
Méthode de synthèse de ADN
|
US7109003B2
(en)
*
|
1998-12-23 |
2006-09-19 |
Abgenix, Inc. |
Methods for expressing and recovering human monoclonal antibodies to CTLA-4
|
JP3793693B2
(ja)
|
1998-12-23 |
2006-07-05 |
ファイザー インコーポレーテッド |
Ctla−4に対するヒトモノクローナル抗体
|
US6682736B1
(en)
|
1998-12-23 |
2004-01-27 |
Abgenix, Inc. |
Human monoclonal antibodies to CTLA-4
|
JP2002537102A
(ja)
|
1999-02-26 |
2002-11-05 |
カイロン コーポレイション |
吸着された高分子および微粒子を有するミクロエマルジョン
|
US7098032B2
(en)
|
2001-01-02 |
2006-08-29 |
Mirus Bio Corporation |
Compositions and methods for drug delivery using pH sensitive molecules
|
US6984720B1
(en)
|
1999-08-24 |
2006-01-10 |
Medarex, Inc. |
Human CTLA-4 antibodies
|
US7605238B2
(en)
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
JP2003520828A
(ja)
|
2000-01-27 |
2003-07-08 |
ジェネティクス インスティテュート,エルエルシー |
Ctla4(cd152)に対する抗体、これを含む結合体、およびその使用
|
US6998115B2
(en)
|
2000-10-10 |
2006-02-14 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
US6649138B2
(en)
|
2000-10-13 |
2003-11-18 |
Quantum Dot Corporation |
Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media
|
US7708915B2
(en)
|
2004-05-06 |
2010-05-04 |
Castor Trevor P |
Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein
|
US6897196B1
(en)
|
2001-02-07 |
2005-05-24 |
The Regents Of The University Of California |
pH sensitive lipids based on ortho ester linkers, composition and method
|
EP1412065A2
(fr)
|
2001-07-27 |
2004-04-28 |
President And Fellows Of Harvard College |
Appareil et procedes de melange de flux laminaires
|
EP1443905A4
(fr)
|
2001-10-03 |
2010-06-23 |
Univ Johns Hopkins |
Compositions pour therapie genique orale et procedes d'utilisation associes
|
US7384739B2
(en)
|
2001-11-14 |
2008-06-10 |
Toyo Boseki Kabushiki Kaisha |
Compositions for enhancing DNA synthesis, DNA polymerase-related factors and utilization thereof
|
CA2409775C
(fr)
|
2001-12-03 |
2010-07-13 |
F. Hoffmann-La Roche Ag |
Enzymes thermostables modifies de facon reversible pour la synthese de l'adn et l'amplification in vitro
|
DK1474109T3
(da)
|
2001-12-21 |
2010-10-25 |
Alcon Inc |
Anvendelse af syntetiske uorganiske nanopartikler som bærere af ophthalmiske lægemidler
|
US20050222064A1
(en)
|
2002-02-20 |
2005-10-06 |
Sirna Therapeutics, Inc. |
Polycationic compositions for cellular delivery of polynucleotides
|
WO2003075892A1
(fr)
|
2002-03-13 |
2003-09-18 |
Novartis Ag |
Microparticules pharmaceutiques
|
AU2003217531A1
(en)
|
2002-05-02 |
2003-11-17 |
Massachusetts Eye And Ear Infirmary |
Ocular drug delivery systems and use thereof
|
US7883720B2
(en)
|
2003-07-09 |
2011-02-08 |
Wisconsin Alumni Research Foundation |
Charge-dynamic polymers and delivery of anionic compounds
|
US8957034B2
(en)
|
2004-01-28 |
2015-02-17 |
Johns Hopkins University |
Drugs and gene carrier particles that rapidly move through mucous barriers
|
US20050232981A1
(en)
|
2004-04-15 |
2005-10-20 |
Ben-Sasson Shmuel A |
Compositions capable of facilitating penetration across a biological barrier
|
US8178656B2
(en)
|
2004-06-11 |
2012-05-15 |
Trustees Of Tufts College |
Silk-based drug delivery system
|
ES2407979T3
(es)
|
2004-12-10 |
2013-06-17 |
Kala Pharmaceuticals, Inc. |
Copolímeros de bloques de poli(éter-anhídrido) funcionalizados
|
US8192718B1
(en)
|
2005-01-04 |
2012-06-05 |
Gp Medical, Inc. |
Pharmaceutical composition of nanoparticles
|
US7404969B2
(en)
|
2005-02-14 |
2008-07-29 |
Sirna Therapeutics, Inc. |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
|
JP5042863B2
(ja)
|
2005-02-14 |
2012-10-03 |
サーナ・セラピューティクス・インコーポレイテッド |
生物学的に活性な分子をデリバリーするための脂質ナノ粒子系組成物および方法
|
AR053026A1
(es)
*
|
2005-03-08 |
2007-04-18 |
Pharmacia & Upjohn Co Llc |
Composiciones de anticuerpos anti factor de estimulacion de colonias de macrofagos (anti-m csf)
|
NZ562064A
(en)
|
2005-04-01 |
2011-03-31 |
Intezyne Technologies Inc |
Polymeric micelles for drug delivery
|
WO2006110776A2
(fr)
|
2005-04-12 |
2006-10-19 |
Nektar Therapeutics Al, Corporation |
Compositions a base de polymere et conjugues d'agents antimicrobiens
|
US7550264B2
(en)
|
2005-06-10 |
2009-06-23 |
Datascope Investment Corporation |
Methods and kits for sense RNA synthesis
|
PT2279758E
(pt)
|
2005-06-16 |
2015-05-27 |
Nektar Therapeutics |
Conjugados possuindo uma ligação degradável e reagentes poliméricos úteis na preparação de tais conjugados
|
AU2006282042B2
(en)
|
2005-06-17 |
2011-12-22 |
The University Of North Carolina At Chapel Hill |
Nanoparticle fabrication methods, systems, and materials
|
CA2613442C
(fr)
|
2005-06-30 |
2016-08-23 |
Archemix Corp. |
Materiaux et procedes pour la generation de transcriptions d'acide nucleiques modifiee en 2'
|
US8101385B2
(en)
|
2005-06-30 |
2012-01-24 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
DE102005046490A1
(de)
|
2005-09-28 |
2007-03-29 |
Johannes-Gutenberg-Universität Mainz |
Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
|
CN101420984B
(zh)
|
2006-02-21 |
2013-01-02 |
尼克塔治疗公司 |
嵌段可降解聚合物及由其制备的轭合物
|
AU2007240986A1
(en)
|
2006-04-04 |
2007-11-01 |
Stc.Unm |
Swellable particles for drug delivery
|
EP2007423A2
(fr)
|
2006-04-05 |
2008-12-31 |
Pfizer Products Incorporated |
Polythérapie à base d'un anticorps anti-ctla4
|
JP5630998B2
(ja)
|
2006-05-15 |
2014-11-26 |
マサチューセッツ インスティテュート オブ テクノロジー |
機能的粒子のためのポリマー
|
DE602007012559D1
(de)
|
2006-09-08 |
2011-03-31 |
Univ Johns Hopkins |
H die schleimhaut
|
MX2009003680A
(es)
|
2006-10-05 |
2009-07-17 |
Univ Johns Hopkins |
Formulaciones orales, parenterales y topicas dispersables en agua para farmacos deficientemente solubles en agua con el uso de nanoparticulas polimericas inteligentes.
|
US8399007B2
(en)
|
2006-12-05 |
2013-03-19 |
Landec Corporation |
Method for formulating a controlled-release pharmaceutical formulation
|
WO2008070118A1
(fr)
|
2006-12-05 |
2008-06-12 |
Landec Corporation |
Administration de médicaments
|
AU2007339280B2
(en)
|
2006-12-21 |
2013-12-05 |
Stryker Corporation |
Sustained-release formulations comprising crystals, macromolecular gels, and particulate suspensions of biologic agents
|
EP2207891B1
(fr)
|
2006-12-22 |
2012-07-25 |
Archemix LLC |
Matériaux et procédés pour la génération de transcrits comprenant des nucléotides modifiés
|
WO2008092117A2
(fr)
*
|
2007-01-25 |
2008-07-31 |
Xencor, Inc. |
Nouvelles insertions, délétions et substitutions d'immunoglobulines
|
EP2131848A4
(fr)
|
2007-02-16 |
2012-06-27 |
Merck Sharp & Dohme |
Compositions et methodes de potentialisation de l'activite de molecules biologiquement actives
|
WO2008109712A2
(fr)
|
2007-03-05 |
2008-09-12 |
Washington University |
Systèmes de distribution de nanoparticules pour des peptides d'intégration de la membrane
|
CN101674853B
(zh)
|
2007-05-04 |
2013-03-27 |
玛瑞纳生物技术有限公司 |
氨基酸脂质及其用途
|
HUE031422T2
(en)
|
2007-09-26 |
2017-07-28 |
Intrexon Corp |
Artificial 5'UTRs, expression vectors, and methods for increasing transgene expression
|
EP2644594B1
(fr)
|
2007-09-28 |
2017-08-23 |
Pfizer Inc |
Ciblage de cellules de cancer utilisant des nanoparticules
|
CA2904904A1
(fr)
|
2007-12-11 |
2009-06-18 |
The Scripps Research Institute |
Compositions et procedes concernant des elements activateurs de traduction de l'arnm
|
HUE034483T2
(en)
|
2008-04-15 |
2018-02-28 |
Protiva Biotherapeutics Inc |
New lipid preparations for introducing a nucleic acid
|
AU2009238607B2
(en)
|
2008-04-25 |
2015-08-06 |
Northwestern University |
Nanostructures suitable for sequestering cholesterol
|
PL215513B1
(pl)
|
2008-06-06 |
2013-12-31 |
Univ Warszawski |
Nowe boranofosforanowe analogi dinukleotydów, ich zastosowanie, czasteczka RNA, sposób otrzymywania RNA oraz sposób otrzymywania peptydów lub bialka
|
ES2462090T5
(es)
|
2008-06-16 |
2017-07-12 |
Pfizer Inc. |
Nanopartículas poliméricas cargadas de fármaco y procedimientos de fabricación y uso de las mismas
|
EP2309991B1
(fr)
|
2008-06-16 |
2019-03-06 |
Pfizer Inc |
Nanoparticules polymères thérapeutiques comprenant des alcaloïdes vinca et procédés de fabrication et d utilisation associés
|
WO2010005726A2
(fr)
|
2008-06-16 |
2010-01-14 |
Bind Biosciences Inc. |
Nanoparticules polymères thérapeutiques avec inhibiteurs de mtor et procédés de fabrication et d’utilisation associés
|
JP2011525180A
(ja)
|
2008-06-16 |
2011-09-15 |
バインド バイオサイエンシズ インコーポレイテッド |
治療的標的化ナノ粒子の製作に用いるためのジブロックコポリマーで官能化された標的薬の製造方法
|
WO2010021865A1
(fr)
|
2008-08-18 |
2010-02-25 |
Merck Sharp & Dohme Corp. |
Nouvelles nanoparticules lipidiques et nouveaux composants pour l'administration d'acides nucléiques
|
US20100087337A1
(en)
|
2008-09-10 |
2010-04-08 |
Bind Biosciences, Inc. |
High Throughput Fabrication of Nanoparticles
|
US20100075072A1
(en)
|
2008-09-25 |
2010-03-25 |
Tsung-Wei Chen |
Decorative structure of tree-shaped bells
|
CA2742954C
(fr)
|
2008-11-07 |
2018-07-10 |
Massachusetts Institute Of Technology |
Lipidoides aminoalcool et leurs utilisations
|
JP2012512175A
(ja)
|
2008-12-15 |
2012-05-31 |
バインド バイオサイエンシズ インコーポレイテッド |
治療薬を徐放するための長時間循環性ナノ粒子
|
WO2010080724A1
(fr)
|
2009-01-12 |
2010-07-15 |
Merck Sharp & Dohme Corp. |
Nanoparticules lipidiques inédites et composants inédits utilisables pour l'administration d'acides nucléiques
|
WO2010087791A1
(fr)
|
2009-01-27 |
2010-08-05 |
Utc Power Corporation |
Réacteur de conversion à la vapeur d'eau intégré, refroidi de manière distributive et atomiseur
|
GB0903325D0
(en)
|
2009-02-26 |
2009-04-08 |
Univ Aberdeen |
Antibody molecules
|
US8714214B2
(en)
|
2009-03-12 |
2014-05-06 |
Illinois Tool Works |
Mis-fuel inhibitor
|
JP5622254B2
(ja)
|
2009-03-31 |
2014-11-12 |
国立大学法人東京大学 |
二本鎖リボ核酸ポリイオンコンプレックス
|
EP2421561A2
(fr)
|
2009-04-21 |
2012-02-29 |
Selecta Biosciences, Inc. |
Composés immunonanothérapeutiques fournissant une réponse immunitaire à forte composante th1
|
US8287910B2
(en)
|
2009-04-30 |
2012-10-16 |
Intezyne Technologies, Inc. |
Polymeric micelles for polynucleotide encapsulation
|
DE202009007116U1
(de)
|
2009-05-18 |
2010-10-14 |
Amoena Medizin-Orthopädie-Technik GmbH |
Antidekubituskissen
|
US8629151B2
(en)
|
2009-05-27 |
2014-01-14 |
Selecta Biosciences, Inc. |
Immunomodulatory agent-polymeric compounds
|
HUE056773T2
(hu)
|
2009-06-10 |
2022-03-28 |
Arbutus Biopharma Corp |
Továbbfejlesztett lipid készítmény
|
WO2011000107A1
(fr)
|
2009-07-01 |
2011-01-06 |
Protiva Biotherapeutics, Inc. |
Formulations lipidiques inédites permettant l'administration d'agents thérapeutiques en direction de tumeurs solides
|
US8569256B2
(en)
|
2009-07-01 |
2013-10-29 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods for the delivery of therapeutic agents
|
EP2467357B1
(fr)
|
2009-08-20 |
2016-03-30 |
Sirna Therapeutics, Inc. |
Nouveaux lipides cationiques avec différents groupes de tête pour délivrance d oligonucléotide
|
EP2485770A4
(fr)
|
2009-10-08 |
2013-04-10 |
Merck Sharp & Dohme |
Nouveaux lipides cationiques à chaînes lipidiques courtes pour une administration d'oligonucléotides
|
CN107028886A
(zh)
|
2009-11-04 |
2017-08-11 |
不列颠哥伦比亚大学 |
含有核酸的脂质粒子及相关的方法
|
US8449916B1
(en)
|
2009-11-06 |
2013-05-28 |
Iowa State University Research Foundation, Inc. |
Antimicrobial compositions and methods
|
GB0920304D0
(en)
|
2009-11-20 |
2010-01-06 |
Medical Res Council |
Novel liposome nanoparticles for tumour magnetic resonance imaging
|
PL3338765T3
(pl)
|
2009-12-01 |
2019-06-28 |
Translate Bio, Inc. |
Pochodna steroidowa dla dostarczania mrna w ludzkich chorobach genetycznych
|
WO2011069529A1
(fr)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Solution contenant du mannose pour la lyophilisation, la transfection et/ou l'injection d'acides nucléiques
|
ES2721898T3
(es)
|
2009-12-11 |
2019-08-06 |
Pfizer |
Formulaciones estables para liofilizar partículas terapéuticas
|
EA201290499A1
(ru)
|
2009-12-15 |
2013-01-30 |
Байнд Байосайенсиз, Инк. |
Композиции терапевтических полимерных наночастиц с высокой температурой стеклования и высокомолекулярными сополимерами
|
EA201290497A1
(ru)
|
2009-12-15 |
2013-01-30 |
Байнд Байосайенсиз, Инк. |
Терапевтические полимерные наночастицы, включающие кортикостероиды, и способы получения таковых
|
JP5898627B2
(ja)
|
2009-12-15 |
2016-04-06 |
バインド セラピューティックス インコーポレイテッド |
エポチロンを含む治療用ポリマーナノ粒子ならびにそれを製造および使用する方法
|
DE102009058769A1
(de)
|
2009-12-16 |
2011-06-22 |
MagForce Nanotechnologies AG, 10589 |
Temperaturabhängige Aktivierung von katalytischen Nukleinsäuren zur kontrollierten Wirkstofffreisetzung
|
BR112012015755B1
(pt)
|
2009-12-23 |
2021-06-22 |
Novartis Ag |
Lipídeo furtivo, e composição
|
US20130116419A1
(en)
|
2010-01-22 |
2013-05-09 |
Daniel Zewge |
Post-synthetic chemical modification of rna at the 2'-position of the ribose ring via "click" chemistry
|
WO2012082165A1
(fr)
|
2010-01-24 |
2012-06-21 |
Novartis Ag |
Microparticules de polymère biodégradable irradiées
|
US9149432B2
(en)
|
2010-03-19 |
2015-10-06 |
Massachusetts Institute Of Technology |
Lipid vesicle compositions and methods of use
|
WO2011119262A1
(fr)
|
2010-03-26 |
2011-09-29 |
Cerulean Pharma Inc. |
Procédés et systèmes de production de nanoparticules
|
WO2011127255A1
(fr)
|
2010-04-08 |
2011-10-13 |
Merck Sharp & Dohme Corp. |
Préparation de nanoparticules de lipide
|
WO2011127456A2
(fr)
|
2010-04-09 |
2011-10-13 |
Pacira Pharmaceuticals, Inc. |
Procédé de formulation de vésicules membranaires synthétiques de grand diamètre
|
US20110262491A1
(en)
|
2010-04-12 |
2011-10-27 |
Selecta Biosciences, Inc. |
Emulsions and methods of making nanocarriers
|
US20130156845A1
(en)
|
2010-04-29 |
2013-06-20 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated single stranded rna
|
US9254327B2
(en)
|
2010-05-10 |
2016-02-09 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for delivery of active agents
|
US20130123338A1
(en)
|
2010-05-12 |
2013-05-16 |
Protiva Biotherapeutics, Inc. |
Novel cationic lipids and methods of use thereof
|
JP2013531634A
(ja)
|
2010-05-24 |
2013-08-08 |
メルク・シャープ・エンド・ドーム・コーポレイション |
オリゴヌクレオチド送達のための新規なアミノアルコールカチオン性脂質
|
CN102858375B
(zh)
|
2010-05-26 |
2016-08-10 |
江苏命码生物科技有限公司 |
载有干扰核糖核酸的细胞微粒子、其制备方法及其应用
|
JP5957646B2
(ja)
|
2010-06-04 |
2016-07-27 |
サーナ・セラピューティクス・インコーポレイテッドSirna Therapeutics,Inc. |
オリゴヌクレオチド送達のための新規な低分子量カチオン性脂質
|
BRPI1001959A2
(pt)
|
2010-06-15 |
2012-03-06 |
Instituto De Pesquisas Tecnológicas Do Est. S. Paulo S/a - Ipt |
Nanocarreadores coloidais para ativos hidrofílicos e processo de produção
|
WO2011163483A2
(fr)
|
2010-06-25 |
2011-12-29 |
Massachusetts Institute Of Technology |
Polymères pour des biomatériaux et des agents thérapeutiques
|
ES2649896T3
(es)
|
2010-07-06 |
2018-01-16 |
Glaxosmithkline Biologicals Sa |
Emulsiones catiónicas de aceite en agua
|
SI4005592T1
(sl)
|
2010-07-06 |
2023-03-31 |
Glaxosmithkline Biologicals S.A. |
Virionom podobni dostavni delci za samopodvojene molekule RNA
|
WO2012006378A1
(fr)
|
2010-07-06 |
2012-01-12 |
Novartis Ag |
Liposomes à lipides ayant une valeur de pka avantageuse pour la délivrance d'arn
|
DE102010032758B4
(de)
|
2010-07-29 |
2012-02-23 |
Fujitsu Technology Solutions Intellectual Property Gmbh |
Computersystem, Verfahren zum Programmieren einer Echtzeituhr und Computerprogrammprodukt
|
DK2449113T3
(en)
|
2010-07-30 |
2016-01-11 |
Curevac Ag |
Complex formation of nucleic acids with the disulfide cross-linked cationic components for transfection and immunostimulation
|
US9121065B2
(en)
|
2010-08-09 |
2015-09-01 |
The Trustees Of The University Of Pennsylvania |
Nanoparticle-oligonucleotide hybrid structures and methods of use thereof
|
WO2012024233A2
(fr)
|
2010-08-14 |
2012-02-23 |
The Regents Of The University Of California |
Lipides zwittérioniques
|
EA201390145A1
(ru)
|
2010-08-20 |
2013-11-29 |
Серулин Фарма Инк. |
Конъюгаты, частицы, композиции и связанные с ними способы
|
AU2011295938B2
(en)
|
2010-08-31 |
2016-01-14 |
Glaxosmithkline Biologicals S.A. |
Lipids suitable for liposomal delivery of protein-coding RNA
|
ES2939732T3
(es)
|
2010-08-31 |
2023-04-26 |
Glaxosmithkline Biologicals Sa |
Liposomas pequeños para la administración de ARN que codifica para inmunógeno
|
DK2611461T3
(da)
|
2010-08-31 |
2022-05-16 |
Glaxosmithkline Biologicals Sa |
Pegylerede liposomer til afgivelse af RNA, der koder immunogen
|
WO2012039979A2
(fr)
|
2010-09-10 |
2012-03-29 |
The Johns Hopkins University |
Diffusion rapide de grosses nanoparticules polymères dans le cerveau de mammifères
|
US8466122B2
(en)
|
2010-09-17 |
2013-06-18 |
Protiva Biotherapeutics, Inc. |
Trialkyl cationic lipids and methods of use thereof
|
US9669097B2
(en)
|
2010-09-20 |
2017-06-06 |
Sirna Therapeutics, Inc. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
EP2619307A1
(fr)
|
2010-09-21 |
2013-07-31 |
RiboxX GmbH |
Procédé pour synthétiser de l'arn en utilisant une matrice d'adn
|
CN103260611A
(zh)
|
2010-09-30 |
2013-08-21 |
默沙东公司 |
用于寡核苷酸递送的低分子量阳离子脂质
|
WO2012051220A1
(fr)
|
2010-10-11 |
2012-04-19 |
Wichita State University |
Système de délivrance de médicaments de nanoparticules magnétiques composites
|
JP2013545727A
(ja)
|
2010-10-21 |
2013-12-26 |
メルク・シャープ・アンド・ドーム・コーポレーション |
オリゴヌクレオチド送達用の新規低分子量カチオン性脂質
|
EP2629760A4
(fr)
|
2010-10-22 |
2014-04-02 |
Bind Therapeutics Inc |
Nanoparticules thérapeutiques contenant des copolymères de masse moléculaire élevée
|
WO2012061259A2
(fr)
|
2010-11-05 |
2012-05-10 |
Merck Sharp & Dohme Corp. |
Amine cyclique inédite de faible masse moléculaire contenant des lipides cationiques en vue de l'administration d'oligonucléotides
|
AU2011323250B2
(en)
|
2010-11-05 |
2015-11-19 |
The Johns Hopkins University |
Compositions and methods relating to reduced mucoadhesion
|
WO2012092552A1
(fr)
|
2010-12-30 |
2012-07-05 |
Selecta Biosciences, Inc. |
Nano-vecteurs synthétiques ayant des groupes réactifs qui libèrent des agents biologiquement actifs
|
EP3202760B1
(fr)
|
2011-01-11 |
2019-08-21 |
Alnylam Pharmaceuticals, Inc. |
Lipides pégylés et leur utilisation pour l'administration de médicaments
|
US20120189700A1
(en)
|
2011-01-19 |
2012-07-26 |
Zoraida Aguilar |
Nanoparticle Based Immunological Stimulation
|
US20140066363A1
(en)
|
2011-02-07 |
2014-03-06 |
Arun K. Bhunia |
Carbohydrate nanoparticles for prolonged efficacy of antimicrobial peptide
|
US8846850B2
(en)
|
2011-02-22 |
2014-09-30 |
Rutgers, The State University Of New Jersey |
Amphiphilic macromolecules for nucleic acid delivery
|
GB201103955D0
(en)
|
2011-03-09 |
2011-04-20 |
Antitope Ltd |
Antibodies
|
WO2012135010A2
(fr)
|
2011-03-25 |
2012-10-04 |
Selecta Biosciences, Inc. |
Nanovecteurs synthétiques à libération médiée par voie osmotique
|
AU2012237260A1
(en)
|
2011-03-31 |
2013-11-14 |
Ingell Technologies Holding B.V. |
Biodegradable compositions suitable for controlled release
|
CA2831471C
(fr)
|
2011-03-31 |
2020-02-25 |
Ingell Technologies Holding B.V. |
Compositions biodegradables appropriees pour une liberation controlee
|
DE12722942T1
(de)
|
2011-03-31 |
2021-09-30 |
Modernatx, Inc. |
Freisetzung und formulierung von manipulierten nukleinsäuren
|
WO2012149393A2
(fr)
|
2011-04-29 |
2012-11-01 |
Selecta Biosciences, Inc. |
Nanovecteurs synthétiques tolérogènes destinés à une délétion, spécifique à un antigène, de cellules effectrices
|
US20120283503A1
(en)
|
2011-04-29 |
2012-11-08 |
The Johns Hopkins University |
Nanoparticle loaded stem cells and their use in mri guided hyperthermia
|
US8691750B2
(en)
|
2011-05-17 |
2014-04-08 |
Axolabs Gmbh |
Lipids and compositions for intracellular delivery of biologically active compounds
|
WO2012166923A2
(fr)
|
2011-05-31 |
2012-12-06 |
Bind Biosciences |
Nanoparticules polymères chargées de médicament et leurs procédés de fabrication et d'utilisation
|
JP6100762B2
(ja)
|
2011-06-02 |
2017-03-22 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
膜で被包されたナノ粒子および使用方法
|
CN111671918A
(zh)
|
2011-06-08 |
2020-09-18 |
川斯勒佰尔公司 |
Mrna递送的脂质纳米颗粒组合物和方法
|
EP3336082B1
(fr)
|
2011-06-08 |
2020-04-15 |
Translate Bio, Inc. |
Lipides clivables
|
EP4014966A1
(fr)
|
2011-07-06 |
2022-06-22 |
GlaxoSmithKline Biologicals S.A. |
Liposomes ayant un rapport n:p utile pour délivrance de molécules d'arn
|
BR112014001050B1
(pt)
|
2011-07-21 |
2017-12-05 |
Croda International Plc |
Polyester polyester block polymer, method for the preparation of the same, composition, controlled release and personal care products, and method for preparing a gel composition
|
CN103702687A
(zh)
|
2011-07-29 |
2014-04-02 |
西莱克塔生物科技公司 |
产生体液和细胞毒性t淋巴细胞(ctl)免疫应答的合成纳米载体
|
US8932572B2
(en)
|
2011-08-26 |
2015-01-13 |
Arrowhead Madison Inc. |
Poly(vinyl ester) polymers for in vivo nucleic acid delivery
|
US9126966B2
(en)
|
2011-08-31 |
2015-09-08 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use thereof
|
KR20140067070A
(ko)
|
2011-08-31 |
2014-06-03 |
말린크로트 엘엘씨 |
H-포스포네이트에 의한 나노입자 peg 개질
|
WO2013039857A1
(fr)
|
2011-09-12 |
2013-03-21 |
modeRNA Therapeutics |
Acides nucléiques modifiés et leurs procédés d'utilisation
|
US20150017245A1
(en)
|
2011-09-22 |
2015-01-15 |
Bind Therapeutics, Inc. |
Methods of treating cancers with therapeutic nanoparticles
|
US9375388B2
(en)
|
2011-09-23 |
2016-06-28 |
Indian Institute Of Technology, Bombay |
Nanoparticle based cosmetic composition
|
EP3492109B1
(fr)
|
2011-10-03 |
2020-03-04 |
ModernaTX, Inc. |
Nucléosides, nucléotides et acides nucléiques modifiés et leurs utilisations
|
MX2014004415A
(es)
|
2011-10-14 |
2015-06-05 |
Stc Unm |
Bicapas lipidicas soportadas por nanoparticulas porosas (protecelulas) para suministro dirigido, incluido el suministro transdermico de carga, y los metodos relacionados.
|
PT3597644T
(pt)
|
2011-10-18 |
2021-11-03 |
Dicerna Pharmaceuticals Inc |
Lípidos catiónicos de amina e suas utilizações
|
WO2013059922A1
(fr)
|
2011-10-25 |
2013-05-02 |
The University Of British Columbia |
Nanoparticules lipides de taille limite, et procédés correspondants
|
CA3119789A1
(fr)
|
2011-10-27 |
2013-05-02 |
Massachusetts Institute Of Technology |
Derives d'acide amine fonctionnalises sur le terminal n capables de former des microspheres encapsulant un medicament
|
SG10201508662SA
(en)
|
2011-10-28 |
2015-11-27 |
Presage Biosciences Inc |
Methods for drug delivery
|
CN103906503B
(zh)
|
2011-11-04 |
2016-12-14 |
日东电工株式会社 |
用于无菌制备脂质-核酸颗粒的单次使用系统
|
AU2012340107B2
(en)
|
2011-11-18 |
2017-06-15 |
Regeneron Pharmaceuticals, Inc. |
Polymer protein microparticles
|
US20150037428A1
(en)
|
2011-11-29 |
2015-02-05 |
The University Of North Carolina At Chapel Hill |
Geometrically engineered particles and methods for modulating macrophage or immune responses
|
US9364549B2
(en)
|
2011-11-30 |
2016-06-14 |
Andreas Voigt |
Hydrophobic drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
|
US20140308304A1
(en)
|
2011-12-07 |
2014-10-16 |
Alnylam Pharmaceuticals, Inc. |
Lipids for the delivery of active agents
|
CA3165769A1
(fr)
|
2011-12-07 |
2013-06-13 |
Alnylam Pharmaceuticals, Inc. |
Lipides biodegradables pour l'administration d'agents actifs
|
GB201121070D0
(en)
|
2011-12-07 |
2012-01-18 |
Isis Innovation |
composition for delivery of biotherapeutics
|
WO2013086526A1
(fr)
|
2011-12-09 |
2013-06-13 |
The Regents Of The University Of California |
Encapsulation liposomale de médicaments
|
US9844598B2
(en)
|
2011-12-13 |
2017-12-19 |
Engeneic Molecular Delivery Pty Ltd |
Bacterially derived, intact minicells for delivery of therapeutic agents to brain tumors
|
JP2015501844A
(ja)
|
2011-12-16 |
2015-01-19 |
モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. |
修飾ヌクレオシド、ヌクレオチドおよび核酸組成物
|
WO2013090601A2
(fr)
|
2011-12-16 |
2013-06-20 |
Massachusetts Institute Of Technology |
Nanoparticules compactes pour des applications biologiques
|
WO2013105101A1
(fr)
|
2012-01-13 |
2013-07-18 |
Department Of Biotechnology |
Nanoparticules lipidiques solides encapsulant un médicament hydrophile/amphiphile et leur procédé de préparation
|
WO2013110028A1
(fr)
|
2012-01-19 |
2013-07-25 |
The Johns Hopkins University |
Formulations de nanoparticules présentant une pénétration améliorée dans les muqueuses
|
WO2013116126A1
(fr)
|
2012-02-01 |
2013-08-08 |
Merck Sharp & Dohme Corp. |
Nouveaux lipides cationiques biodégradables de faible masse moléculaire pour la délivrance d'oligonucléotides
|
WO2013116804A2
(fr)
|
2012-02-03 |
2013-08-08 |
Rutgers, The State Of University Of New Jersey |
Biomatériaux polymères dérivés de monomères phénoliques et leurs utilisations à des fins médicales
|
WO2013119602A1
(fr)
|
2012-02-06 |
2013-08-15 |
President And Fellows Of Harvard College |
Microvésicules médiées par arrdc1 (armm) et leurs utilisations
|
EP4116338A1
(fr)
|
2012-02-09 |
2023-01-11 |
Life Technologies Corporation |
Particules polymères hydrophiles et procédés pour les préparer
|
JP2015513788A
(ja)
|
2012-02-10 |
2015-05-14 |
イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company |
高度xジブロックコポリマーの製造、精製及び使用
|
CN104394853B
(zh)
|
2012-02-19 |
2017-10-10 |
纳维基因股份有限公司 |
多孔性纳米结构在递送中的用途
|
JP6275655B2
(ja)
|
2012-02-24 |
2018-02-07 |
プロティバ バイオセラピューティクス インコーポレイテッド |
トリアルキルカチオン性脂質およびその使用方法
|
AU2013243949A1
(en)
|
2012-04-02 |
2014-10-30 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of biologics and proteins associated with human disease
|
EP2833923A4
(fr)
|
2012-04-02 |
2016-02-24 |
Moderna Therapeutics Inc |
Polynucléotides modifiés pour la production de protéines
|
EP2885419A4
(fr)
|
2012-08-14 |
2016-05-25 |
Moderna Therapeutics Inc |
Enzymes et polymérases destinées à la synthèse d'arn
|
US20150307542A1
(en)
|
2012-10-03 |
2015-10-29 |
Moderna Therapeutics, Inc. |
Modified nucleic acid molecules and uses thereof
|
EP2964234A4
(fr)
|
2013-03-09 |
2016-12-07 |
Moderna Therapeutics Inc |
Régions non traduites hétérologues pour arnm
|
EP2971010B1
(fr)
|
2013-03-14 |
2020-06-10 |
ModernaTX, Inc. |
Formulation et administration de compositions de nucléosides, de nucléotides, et d'acides nucléiques modifiés
|
WO2014209804A1
(fr)
|
2013-06-24 |
2014-12-31 |
Biomed Valley Discoveries, Inc. |
Anticorps bispécifiques
|
EP3041934A1
(fr)
|
2013-09-03 |
2016-07-13 |
Moderna Therapeutics, Inc. |
Polynucléotides chimériques
|
WO2015034925A1
(fr)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Polynucléotides circulaires
|
EP4071177A1
(fr)
*
|
2013-12-30 |
2022-10-12 |
Epimab Biotherapeutics, Inc. |
Immunoglobuline fabs-in-tandem et ses utilisations
|