DK2691079T3 - Bionedbrydelige sammensætninger, der er egnet til kontrolleret udløsning - Google Patents
Bionedbrydelige sammensætninger, der er egnet til kontrolleret udløsning Download PDFInfo
- Publication number
- DK2691079T3 DK2691079T3 DK12712652.2T DK12712652T DK2691079T3 DK 2691079 T3 DK2691079 T3 DK 2691079T3 DK 12712652 T DK12712652 T DK 12712652T DK 2691079 T3 DK2691079 T3 DK 2691079T3
- Authority
- DK
- Denmark
- Prior art keywords
- controlled release
- compositions suitable
- biodegradable compositions
- biodegradable
- release
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
- A61K38/385—Serum albumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0442—Polymeric X-ray contrast-enhancing agent comprising a halogenated group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0457—Semi-solid forms, ointments, gels, hydrogels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
- C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/68—Polyesters containing atoms other than carbon, hydrogen and oxygen
- C08G63/682—Polyesters containing atoms other than carbon, hydrogen and oxygen containing halogens
- C08G63/6822—Polyesters containing atoms other than carbon, hydrogen and oxygen containing halogens derived from hydroxy carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/06—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/06—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules
- A61K51/065—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules conjugates with carriers being macromolecules
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11002675 | 2011-03-31 | ||
PCT/EP2012/055993 WO2012131104A2 (en) | 2011-03-31 | 2012-04-02 | Biodegradable compositions suitable for controlled release |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2691079T3 true DK2691079T3 (da) | 2020-09-28 |
Family
ID=44342954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK12712652.2T DK2691079T3 (da) | 2011-03-31 | 2012-04-02 | Bionedbrydelige sammensætninger, der er egnet til kontrolleret udløsning |
Country Status (7)
Country | Link |
---|---|
US (1) | US9901554B2 (da) |
EP (1) | EP2691079B1 (da) |
AU (1) | AU2012237260A1 (da) |
CA (1) | CA2831469C (da) |
DK (1) | DK2691079T3 (da) |
ES (1) | ES2820369T3 (da) |
WO (1) | WO2012131104A2 (da) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20140102759A (ko) | 2011-12-16 | 2014-08-22 | 모더나 세라퓨틱스, 인코포레이티드 | 변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물 |
EP2833892A4 (en) | 2012-04-02 | 2016-07-20 | Moderna Therapeutics Inc | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS AND PEPTIDES ASSOCIATED WITH ONCOLOGY |
WO2013151666A2 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of biologics and proteins associated with human disease |
EP2943209B8 (en) | 2013-01-09 | 2021-04-07 | NeXtGen Biologics, Inc. | Decellularized biomaterial form non-mammalian tissue |
WO2014152211A1 (en) | 2013-03-14 | 2014-09-25 | Moderna Therapeutics, Inc. | Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions |
US20160194368A1 (en) | 2013-09-03 | 2016-07-07 | Moderna Therapeutics, Inc. | Circular polynucleotides |
AU2014315287A1 (en) | 2013-09-03 | 2015-03-12 | Moderna Therapeutics, Inc. | Chimeric polynucleotides |
US10323076B2 (en) | 2013-10-03 | 2019-06-18 | Modernatx, Inc. | Polynucleotides encoding low density lipoprotein receptor |
FR3018451A1 (fr) * | 2014-03-13 | 2015-09-18 | Chromalys | Nanoparticules pour leur utilisation dans la detection de tumeurs mobiles |
CA2946476C (en) | 2014-05-01 | 2022-08-30 | Ingell Technologies Holding B.V. | Liquid triblock copolymer |
CA2955250A1 (en) | 2014-07-16 | 2016-01-21 | Moderna Therapeutics, Inc. | Chimeric polynucleotides |
US20170210788A1 (en) | 2014-07-23 | 2017-07-27 | Modernatx, Inc. | Modified polynucleotides for the production of intrabodies |
JP6921833B2 (ja) | 2015-10-22 | 2021-08-18 | モデルナティーエックス, インコーポレイテッド | ヒトサイトメガロウイルスワクチン |
EP3365008A4 (en) | 2015-10-22 | 2019-08-07 | ModernaTX, Inc. | VACCINE AGAINST RESPIRATORY SYNZYTIAL VIRUS |
BR112018008090A2 (pt) | 2015-10-22 | 2018-11-13 | Modernatx Inc | vacina de vírus do herpes simplex. |
MA47016A (fr) | 2015-10-22 | 2018-08-29 | Modernatx Inc | Vaccins contre les virus respiratoires |
TW201729838A (zh) | 2015-10-22 | 2017-09-01 | 現代公司 | 用於水痘帶狀疱疹病毒 (vzv)之核酸疫苗 |
JP7384512B2 (ja) | 2015-10-22 | 2023-11-21 | モデルナティエックス インコーポレイテッド | 広域インフルエンザウイルスワクチン |
ES2919552T3 (es) | 2015-12-23 | 2022-07-27 | Modernatx Inc | Procedimientos de utilización de polinucleotidos codificadores de ligando ox40 |
EP3400023A1 (en) | 2016-01-10 | 2018-11-14 | ModernaTX, Inc. | Therapeutic mrnas encoding anti ctla-4 antibodies |
CN107011505B (zh) * | 2017-03-05 | 2019-05-14 | 北京化工大学 | 一种聚乳酸多孔微球的制备方法 |
AR113097A1 (es) | 2017-07-17 | 2020-01-29 | Medincell | Mezclas de composiciones biodegradables que modulan la cinética de liberación de al menos un ingrediente activo en la administración de fármacos |
WO2020056161A1 (en) | 2018-09-12 | 2020-03-19 | University Of Florida Research Foundation, Inc. | Slow-cycling cell-rna based nanoparticle vaccine to treat cancer |
US20200121605A1 (en) * | 2018-10-19 | 2020-04-23 | South Dakota Board Of Regents | Methods and compositions for localized intraductal drug delivery to the breast and regional lymph nodes |
DK4037660T3 (da) | 2019-09-30 | 2024-01-02 | Tolmar International Ltd | Flydende polymersammensætninger og systemer til forlænget levering af peptider som aktive farmaceutiske ingredienser |
WO2023161350A1 (en) | 2022-02-24 | 2023-08-31 | Io Biotech Aps | Nucleotide delivery of cancer therapy |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5352515A (en) | 1992-03-02 | 1994-10-04 | American Cyanamid Company | Coating for tissue drag reduction |
US5702717A (en) | 1995-10-25 | 1997-12-30 | Macromed, Inc. | Thermosensitive biodegradable polymers based on poly(ether-ester)block copolymers |
DE19545327C2 (de) | 1995-12-05 | 2001-04-19 | Fraunhofer Ges Forschung | Verfahren zur Herstellung von hydrophobierten resorbierbaren Polyestern und deren Verwendung |
US6201072B1 (en) * | 1997-10-03 | 2001-03-13 | Macromed, Inc. | Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
US7018645B1 (en) | 2000-04-27 | 2006-03-28 | Macromed, Inc. | Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties |
US7790141B2 (en) | 2003-08-11 | 2010-09-07 | Pathak Holdings, Llc | Radio-opaque compounds, compositions containing same and methods of their synthesis and use |
DE102005033101A1 (de) | 2005-07-15 | 2007-01-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Resorbierbare Polyetherester und ihre Verwendung zur Herstellung von medizinischen Implantaten |
US8545865B2 (en) | 2006-03-24 | 2013-10-01 | Boston Scientific Scimed, Inc. | Medical devices having polymer brushes |
US7740877B2 (en) * | 2006-04-07 | 2010-06-22 | University Of Utah Research Foundation | Aliphatically modified biodegradable block copolymers as thermogelling polymers |
CN101862454B (zh) | 2009-04-20 | 2013-04-10 | 复旦大学 | 一种物理交联的水凝胶组合物及其制备方法和应用 |
EP2343046A1 (en) | 2010-01-08 | 2011-07-13 | Nirvana's Tree House B.V. | Functionalised triblock copolymers and compositions containing such polymers |
-
2012
- 2012-04-02 EP EP12712652.2A patent/EP2691079B1/en active Active
- 2012-04-02 WO PCT/EP2012/055993 patent/WO2012131104A2/en active Application Filing
- 2012-04-02 CA CA2831469A patent/CA2831469C/en active Active
- 2012-04-02 ES ES12712652T patent/ES2820369T3/es active Active
- 2012-04-02 DK DK12712652.2T patent/DK2691079T3/da active
- 2012-04-02 US US14/008,645 patent/US9901554B2/en active Active
- 2012-04-02 AU AU2012237260A patent/AU2012237260A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2012131104A3 (en) | 2013-01-03 |
EP2691079A2 (en) | 2014-02-05 |
US20140219923A1 (en) | 2014-08-07 |
CA2831469A1 (en) | 2012-10-04 |
EP2691079B1 (en) | 2020-06-24 |
AU2012237260A1 (en) | 2013-11-14 |
WO2012131104A2 (en) | 2012-10-04 |
US9901554B2 (en) | 2018-02-27 |
CA2831469C (en) | 2020-02-18 |
ES2820369T3 (es) | 2021-04-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK2691079T3 (da) | Bionedbrydelige sammensætninger, der er egnet til kontrolleret udløsning | |
LTPA2018516I1 (lt) | Testosterono kompozicijos | |
DK2714735T3 (da) | Antistoffer, der er specifikke for TGF-beta | |
BR112013022112A2 (pt) | composição | |
BR112013022102A2 (pt) | composição | |
BR112013017183A2 (pt) | composições de bepostatina | |
BR112013030885A2 (pt) | composição de stevia. | |
DK2686017T3 (da) | Oftalmisk sammensætning | |
BR112014004395A2 (pt) | composição | |
DK2665486T3 (da) | Sammensætninger til modulering af gamma-c-cytokin-aktivitet | |
DK2364795T3 (da) | Coatingsammensætning til støbegods | |
ZA201202474B (en) | Controlled release compositions | |
CO6880065A2 (es) | Nuevos compuestos de 4-piperidinilo para uso como inhibidores de la tankirasa | |
BR112013028128A2 (pt) | composição de polímero para dispositivos elétricos | |
DK2741763T3 (da) | Sammensætning til kontrolleret ovariestimulering. | |
BR112014009802A2 (pt) | composições de bismaleimida contendo nanossílica | |
DK2623288T3 (da) | Fremgangsmåde til fremstilling af formstøbte skumdele | |
BR112013033808A2 (pt) | composição | |
DK2787982T3 (da) | Sammensætning til tarmpræparat | |
DE112012003251A5 (de) | Ausrücksystem | |
BR112013028282A2 (pt) | composição de polímero para dispositivos elétricos | |
DK2768442T3 (da) | Fastgørelsesmekanisme til stomiposer | |
BR112015008572A2 (pt) | formulações de liberação modificada para oprozomib | |
DE112012003262A5 (de) | Ausrücksystem | |
DK2872536T3 (da) | Fremgangsmåde til ekstraktion af biomasse |