DK4037660T3 - Flydende polymersammensætninger og systemer til forlænget levering af peptider som aktive farmaceutiske ingredienser - Google Patents

Flydende polymersammensætninger og systemer til forlænget levering af peptider som aktive farmaceutiske ingredienser Download PDF

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Publication number
DK4037660T3
DK4037660T3 DK20789268.8T DK20789268T DK4037660T3 DK 4037660 T3 DK4037660 T3 DK 4037660T3 DK 20789268 T DK20789268 T DK 20789268T DK 4037660 T3 DK4037660 T3 DK 4037660T3
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DK
Denmark
Prior art keywords
peptides
systems
active pharmaceutical
polymer compositions
liquid polymer
Prior art date
Application number
DK20789268.8T
Other languages
English (en)
Inventor
Hima Bindu Gottam
Casas Gerhard Kummerow
John Charles Middleton
Avinash Nangia
Original Assignee
Tolmar International Ltd
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Application filed by Tolmar International Ltd filed Critical Tolmar International Ltd
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Publication of DK4037660T3 publication Critical patent/DK4037660T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66Polyesters containing oxygen in the form of ether groups
    • C08G63/664Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK20789268.8T 2019-09-30 2020-09-28 Flydende polymersammensætninger og systemer til forlænget levering af peptider som aktive farmaceutiske ingredienser DK4037660T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962908340P 2019-09-30 2019-09-30
PCT/IB2020/059058 WO2021064550A1 (en) 2019-09-30 2020-09-28 Liquid polymer compositions and systems for extended delivery of peptides as active pharmaceutical ingredients

Publications (1)

Publication Number Publication Date
DK4037660T3 true DK4037660T3 (da) 2024-01-02

Family

ID=72811904

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20789268.8T DK4037660T3 (da) 2019-09-30 2020-09-28 Flydende polymersammensætninger og systemer til forlænget levering af peptider som aktive farmaceutiske ingredienser

Country Status (16)

Country Link
US (1) US20220362383A1 (da)
EP (2) EP4302773A1 (da)
JP (1) JP2022551818A (da)
KR (1) KR20220075338A (da)
CN (1) CN114746080A (da)
AR (1) AR120120A1 (da)
AU (1) AU2020358364A1 (da)
BR (1) BR112022004856A2 (da)
CA (1) CA3154134A1 (da)
DK (1) DK4037660T3 (da)
ES (1) ES2966371T3 (da)
FI (1) FI4037660T3 (da)
MX (1) MX2022003246A (da)
TW (1) TW202126321A (da)
UY (1) UY38900A (da)
WO (1) WO2021064550A1 (da)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US6201072B1 (en) 1997-10-03 2001-03-13 Macromed, Inc. Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US20080247987A1 (en) * 2005-08-04 2008-10-09 Angiotech International Ag Block Copolymer Compositions and Uses Thereof
US7740877B2 (en) 2006-04-07 2010-06-22 University Of Utah Research Foundation Aliphatically modified biodegradable block copolymers as thermogelling polymers
US20090181068A1 (en) 2008-01-14 2009-07-16 Dunn Richard L Low Viscosity Liquid Polymeric Delivery System
WO2012005594A2 (en) * 2010-07-09 2012-01-12 Innocore Technologies B.V. Biodegradable phase separated segmented multi block co-polymers and release of biologically active polypeptides
AU2012237260A1 (en) 2011-03-31 2013-11-14 Ingell Technologies Holding B.V. Biodegradable compositions suitable for controlled release
CA2946476C (en) * 2014-05-01 2022-08-30 Ingell Technologies Holding B.V. Liquid triblock copolymer
PT3331495T (pt) 2015-08-03 2020-12-07 Tolmar International Ltd ¿sistema de distribuição de polímero líquido para administração prolongada de fármacos
US11752099B2 (en) * 2017-03-27 2023-09-12 W. L. Gore & Associates, Inc. Injectable and biodegradable polymer formulations for controlled release of bioactive agents

Also Published As

Publication number Publication date
KR20220075338A (ko) 2022-06-08
CN114746080A (zh) 2022-07-12
EP4037660B1 (en) 2023-11-22
MX2022003246A (es) 2022-04-26
WO2021064550A1 (en) 2021-04-08
TW202126321A (zh) 2021-07-16
UY38900A (es) 2021-04-30
AR120120A1 (es) 2022-02-02
EP4302773A1 (en) 2024-01-10
AU2020358364A1 (en) 2022-03-31
EP4037660A1 (en) 2022-08-10
JP2022551818A (ja) 2022-12-14
ES2966371T3 (es) 2024-04-22
US20220362383A1 (en) 2022-11-17
BR112022004856A2 (pt) 2022-06-07
FI4037660T3 (fi) 2023-12-14
CA3154134A1 (en) 2021-04-08

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