|
US8895610B1
(en)
|
2007-05-18 |
2014-11-25 |
Heldi Kay |
Platinum (IV) compounds targeting zinc finger domains
|
|
EA020753B1
(ru)
|
2008-06-16 |
2015-01-30 |
Бинд Терапьютикс, Инк. |
Терапевтические полимерные наночастицы, содержащие алкалоиды vinca, и их применение
|
|
WO2010005726A2
(en)
|
2008-06-16 |
2010-01-14 |
Bind Biosciences Inc. |
Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same
|
|
PL2285350T3
(pl)
*
|
2008-06-16 |
2018-03-30 |
Pfizer Inc. |
Sposoby otrzymywania funkcjonalizowanych kopolimerów dwublokowych stanowiących środki kierujące do stosowania przy wytwarzaniu nanocząstek terapeutycznych
|
|
ES2765240T3
(es)
|
2008-06-16 |
2020-06-08 |
Pfizer |
Nanopartículas poliméricas cargadas de fármaco y procedimientos de fabricación y uso de las mismas
|
|
US9324473B2
(en)
*
|
2008-08-25 |
2016-04-26 |
Kent State University |
Nanoparticle composition, a device and a method thereof
|
|
WO2010068866A2
(en)
|
2008-12-12 |
2010-06-17 |
Bind Biosciences |
Therapeutic particles suitable for parenteral administration and methods of making and using same
|
|
ES2776126T3
(es)
|
2008-12-15 |
2020-07-29 |
Pfizer |
Nanopartículas de circulación prolongada para la liberación sostenida de agentes terapéuticos
|
|
US20100266642A1
(en)
*
|
2009-02-20 |
2010-10-21 |
Bind Biosciences, Inc. |
Modified cells for targeted cell trafficking and uses thereof
|
|
WO2010114770A1
(en)
*
|
2009-03-30 |
2010-10-07 |
Cerulean Pharma Inc. |
Polymer-agent conjugates, particles, compositions, and related methods of use
|
|
EA201171195A8
(ru)
*
|
2009-03-30 |
2014-08-29 |
Серулин Фарма Инк. |
Конъюгаты, частицы, композиции "полимер-агент" и способы их применения
|
|
WO2011072218A2
(en)
|
2009-12-11 |
2011-06-16 |
Bind Biosciences |
Stable formulations for lyophilizing therapeutic particles
|
|
WO2011084513A2
(en)
|
2009-12-15 |
2011-07-14 |
Bind Biosciences, Inc. |
Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers
|
|
CN101773675B
(zh)
*
|
2010-03-05 |
2012-05-30 |
中山大学 |
一种负载液态氟碳的聚合物纳米超声显像囊泡及其制备方法
|
|
WO2011119995A2
(en)
|
2010-03-26 |
2011-09-29 |
Cerulean Pharma Inc. |
Formulations and methods of use
|
|
US8207290B2
(en)
|
2010-03-26 |
2012-06-26 |
Cerulean Pharma Inc. |
Methods and systems for generating nanoparticles
|
|
KR101222368B1
(ko)
*
|
2010-05-20 |
2013-01-15 |
로베르트 보쉬 게엠베하 |
이차 전지
|
|
US8822663B2
(en)
|
2010-08-06 |
2014-09-02 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
US20120070503A1
(en)
*
|
2010-09-20 |
2012-03-22 |
Southwest Research Institute |
Nanoparticle-Based Targeted Drug Delivery For In Vivo Bone Loss Mitigation
|
|
DK4108671T3
(da)
|
2010-10-01 |
2025-01-06 |
Modernatx Inc |
Modificerede nukleosider, nukleotider og nukleinsyrer samt anvendelser deraf
|
|
RU2013127625A
(ru)
|
2010-11-18 |
2014-12-27 |
Зе Дженерал Хоспитал Корпорейшен |
Новые композиции и применения антигипертензивных средств для терапии рака
|
|
WO2012103182A1
(en)
|
2011-01-28 |
2012-08-02 |
Cerulean Pharma Inc. |
Method for fabricating nanoparticles
|
|
JP2014511687A
(ja)
|
2011-03-31 |
2014-05-19 |
モデルナ セラピューティクス インコーポレイテッド |
工学操作された核酸の送達および製剤
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
JP6113737B2
(ja)
|
2011-10-03 |
2017-04-12 |
モデルナティエックス インコーポレイテッドModernaTX,Inc. |
修飾型のヌクレオシド、ヌクレオチドおよび核酸、ならびにそれらの使用方法
|
|
ES2885523T3
(es)
|
2011-11-23 |
2021-12-14 |
Therapeuticsmd Inc |
Formulaciones y terapias de reposición hormonal de combinación naturales
|
|
US9301920B2
(en)
|
2012-06-18 |
2016-04-05 |
Therapeuticsmd, Inc. |
Natural combination hormone replacement formulations and therapies
|
|
KR20140102759A
(ko)
|
2011-12-16 |
2014-08-22 |
모더나 세라퓨틱스, 인코포레이티드 |
변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물
|
|
CN102525937B
(zh)
*
|
2012-01-21 |
2013-07-17 |
中国农业科学院兰州畜牧与兽药研究所 |
一种金丝桃素白蛋白纳米粒的制备方法
|
|
US20130195752A1
(en)
|
2012-02-01 |
2013-08-01 |
Regents Of The University Of Minnesota |
Functionalized nanoparticles and methods of use thereof
|
|
EP2634179A1
(en)
*
|
2012-02-28 |
2013-09-04 |
Sanofi |
Functional PLA-PEG copolymers, the nanoparticles thereof, their preparation and use for targeted drug delivery and imaging
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
HK1206612A1
(en)
|
2012-04-02 |
2016-01-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of secreted proteins
|
|
EP2834259A4
(en)
|
2012-04-02 |
2016-08-24 |
Moderna Therapeutics Inc |
MODIFIED POLYNUCLEOTIDES
|
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
|
US10806697B2
(en)
|
2012-12-21 |
2020-10-20 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
|
US20150196640A1
(en)
|
2012-06-18 |
2015-07-16 |
Therapeuticsmd, Inc. |
Progesterone formulations having a desirable pk profile
|
|
US20130338122A1
(en)
|
2012-06-18 |
2013-12-19 |
Therapeuticsmd, Inc. |
Transdermal hormone replacement therapies
|
|
US10806740B2
(en)
|
2012-06-18 |
2020-10-20 |
Therapeuticsmd, Inc. |
Natural combination hormone replacement formulations and therapies
|
|
EP2882459A1
(en)
|
2012-08-10 |
2015-06-17 |
University of North Texas Health Science Center |
Drug delivery vehicle comprising conjugates between targeting polyamino acids and fatty acids
|
|
PT2895156T
(pt)
|
2012-09-17 |
2019-06-28 |
Pfizer |
Processo para a preparação de nanopartículas terapêuticas
|
|
WO2014058974A1
(en)
*
|
2012-10-10 |
2014-04-17 |
Emory University |
Methods of managing inflammation using glycolysis pathway inhibitors
|
|
US9597380B2
(en)
|
2012-11-26 |
2017-03-21 |
Modernatx, Inc. |
Terminally modified RNA
|
|
US10568891B2
(en)
|
2012-12-21 |
2020-02-25 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
|
US9180091B2
(en)
|
2012-12-21 |
2015-11-10 |
Therapeuticsmd, Inc. |
Soluble estradiol capsule for vaginal insertion
|
|
US11266661B2
(en)
|
2012-12-21 |
2022-03-08 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
|
US11246875B2
(en)
|
2012-12-21 |
2022-02-15 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
|
US10537581B2
(en)
|
2012-12-21 |
2020-01-21 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
|
US10471072B2
(en)
|
2012-12-21 |
2019-11-12 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
|
US10258698B2
(en)
|
2013-03-14 |
2019-04-16 |
Modernatx, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
US9784730B2
(en)
|
2013-03-21 |
2017-10-10 |
University Of Washington Through Its Center For Commercialization |
Nanoparticle for targeting brain tumors and delivery of O6-benzylguanine
|
|
WO2014191502A1
(en)
|
2013-05-28 |
2014-12-04 |
Sinvent As |
Process for preparing stealth nanoparticles
|
|
DK3019619T3
(da)
|
2013-07-11 |
2021-10-11 |
Modernatx Inc |
Sammensætninger, der omfatter syntetiske polynukleotider, som koder for crispr-beslægtede proteiner, og syntetiske sgrna'er, og anvendelsesfremgangsmåder
|
|
AU2014315287A1
(en)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Chimeric polynucleotides
|
|
EP3041938A1
(en)
|
2013-09-03 |
2016-07-13 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
|
DK3046584T3
(en)
|
2013-09-16 |
2017-10-02 |
Astrazeneca Ab |
THERAPEUTIC POLYMER NANOPARTICLES AND PROCEDURES FOR PREPARING AND USING THEREOF
|
|
US10023626B2
(en)
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
EP3052521A1
(en)
|
2013-10-03 |
2016-08-10 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding low density lipoprotein receptor
|
|
US10232058B2
(en)
|
2013-10-14 |
2019-03-19 |
The Johns Hopkins University |
Prostate-specific membrane antigen-targeted photosensitizers for photodynamic therapy
|
|
KR102507624B1
(ko)
|
2013-11-22 |
2023-03-09 |
미나 테라퓨틱스 리미티드 |
C/ebp 알파 짧은 활성화 rna 조성물 및 사용 방법
|
|
EP3079668A1
(en)
|
2013-12-09 |
2016-10-19 |
Durect Corporation |
Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
|
|
JP6443907B2
(ja)
*
|
2014-02-17 |
2018-12-26 |
浩文 山本 |
造影剤の腫瘍への集積を促進するための集積促進剤
|
|
SI3116547T1
(sl)
|
2014-03-14 |
2019-08-30 |
Pfizer, Inc. |
Terapevtski nanodelci, ki obsegajo terapevtsko stredstvo, in postopek izdelave ter uporabe le-teh
|
|
SG10201911695SA
(en)
|
2014-05-14 |
2020-01-30 |
Targimmune Therapeutics Ag |
Improved polyethyleneimine polyethyleneglycol vectors
|
|
MX2016014281A
(es)
|
2014-05-22 |
2017-02-22 |
Therapeuticsmd Inc |
Formulaciones y terapias de reemplazo de combinación de hormonas naturales.
|
|
IL289934B2
(en)
|
2014-06-25 |
2023-04-01 |
Acuitas Therapeutics Inc |
Novel lipids and lipid nanoparticle formulations for delivery of nucleic acids
|
|
EP3169693B1
(en)
|
2014-07-16 |
2022-03-09 |
ModernaTX, Inc. |
Chimeric polynucleotides
|
|
EP3171895A1
(en)
|
2014-07-23 |
2017-05-31 |
Modernatx, Inc. |
Modified polynucleotides for the production of intrabodies
|
|
CN104551003B
(zh)
*
|
2014-12-30 |
2016-08-24 |
燕山大学 |
一种以醋酸兰瑞肽为模板制备纳米铂螺旋杆的方法
|
|
CN104546729A
(zh)
*
|
2015-01-22 |
2015-04-29 |
浙江大学 |
一种pgj2纳米粒的制备及应用
|
|
WO2016162229A1
(en)
|
2015-04-10 |
2016-10-13 |
Capsugel Belgium N.V. |
Abiraterone acetate lipid formulations
|
|
CN114085198A
(zh)
|
2015-06-29 |
2022-02-25 |
爱康泰生治疗公司 |
用于递送核酸的脂质和脂质纳米颗粒制剂
|
|
US10328087B2
(en)
|
2015-07-23 |
2019-06-25 |
Therapeuticsmd, Inc. |
Formulations for solubilizing hormones
|
|
EP3350157B1
(en)
|
2015-09-17 |
2022-01-05 |
Modernatx, Inc. |
Compounds and compositions for intracellular delivery of therapeutic agents
|
|
MA47016A
(fr)
|
2015-10-22 |
2018-08-29 |
Modernatx Inc |
Vaccins contre les virus respiratoires
|
|
JP6925688B2
(ja)
|
2015-10-22 |
2021-08-25 |
モデルナティーエックス, インコーポレイテッド |
水痘帯状疱疹ウイルス(vzv)のための核酸ワクチン
|
|
JP7687767B2
(ja)
|
2015-10-22 |
2025-06-03 |
モデルナティエックス インコーポレイテッド |
呼吸器合胞体ウイルスワクチン
|
|
BR112018008090A2
(pt)
|
2015-10-22 |
2018-11-13 |
Modernatx Inc |
vacina de vírus do herpes simplex.
|
|
CA3002922A1
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
CA3003103A1
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Broad spectrum influenza virus vaccine
|
|
RS63986B1
(sr)
|
2015-10-28 |
2023-03-31 |
Acuitas Therapeutics Inc |
Novi lipidi i lipidne formulacije nanočestica za isporuku nukleinskih kiselina
|
|
CN105458287B
(zh)
*
|
2015-11-30 |
2017-05-31 |
燕山大学 |
利用醋酸兰瑞肽模板制备笼状金纳米粒子的方法
|
|
ES2924407T3
(es)
|
2015-12-10 |
2022-10-06 |
Modernatx Inc |
Composiciones y procedimientos para el suministro de agentes terapéuticos
|
|
US11433136B2
(en)
|
2015-12-18 |
2022-09-06 |
The General Hospital Corporation |
Polyacetal polymers, conjugates, particles and uses thereof
|
|
SI3394030T1
(sl)
|
2015-12-22 |
2022-04-29 |
Modernatx, Inc. |
Sestave za doziranje sredstev v celice
|
|
LT3394093T
(lt)
|
2015-12-23 |
2022-04-25 |
Modernatx, Inc. |
Ox40 ligandus koduojančių polinukleotidų naudojimo būdai
|
|
KR101804953B1
(ko)
|
2015-12-29 |
2017-12-06 |
영남대학교 산학협력단 |
바이오 패치 및 그 제조방법
|
|
EP3400023A1
(en)
|
2016-01-10 |
2018-11-14 |
ModernaTX, Inc. |
Therapeutic mrnas encoding anti ctla-4 antibodies
|
|
US10213448B2
(en)
|
2016-03-25 |
2019-02-26 |
Novazoi Theranostics |
Ethanolamine-based lipid biosynthetic compounds, method of making and use thereof
|
|
US10286077B2
(en)
|
2016-04-01 |
2019-05-14 |
Therapeuticsmd, Inc. |
Steroid hormone compositions in medium chain oils
|
|
AU2017239645A1
(en)
|
2016-04-01 |
2018-10-18 |
Therapeuticsmd, Inc. |
Steroid hormone pharmaceutical composition
|
|
KR102775461B1
(ko)
*
|
2016-04-01 |
2025-02-28 |
어비디티 바이오사이언시스 인크. |
핵산-폴리펩타이드 조성물 및 이의 용도
|
|
KR101806740B1
(ko)
|
2016-10-06 |
2017-12-07 |
현대자동차주식회사 |
자기조립구조를 제어 가능한 카르바졸 기반의 그래프트 공중합체 및 이의 합성방법
|
|
US11583504B2
(en)
|
2016-11-08 |
2023-02-21 |
Modernatx, Inc. |
Stabilized formulations of lipid nanoparticles
|
|
WO2018104540A1
(en)
|
2016-12-08 |
2018-06-14 |
Curevac Ag |
Rnas for wound healing
|
|
JP2020501545A
(ja)
|
2016-12-08 |
2020-01-23 |
キュアバック アーゲー |
肝疾患の処置または予防のためのrna
|
|
ES2911186T3
(es)
|
2017-03-15 |
2022-05-18 |
Modernatx Inc |
Formas cristalinas de aminolípidos
|
|
FI3596041T3
(fi)
|
2017-03-15 |
2023-01-31 |
|
Yhdiste ja koostumuksia terapeuttisten aineiden antamiseen solun sisään
|
|
JP7332478B2
(ja)
|
2017-03-15 |
2023-08-23 |
モデルナティエックス インコーポレイテッド |
脂質ナノ粒子製剤
|
|
CN108653746B
(zh)
*
|
2017-03-29 |
2021-04-27 |
北京键凯科技股份有限公司 |
一种多载药点、高载药配基药物偶联物
|
|
US9996527B1
(en)
|
2017-03-30 |
2018-06-12 |
International Business Machines Corporation |
Supporting interactive text mining process with natural language and dialog
|
|
WO2018200943A1
(en)
|
2017-04-28 |
2018-11-01 |
Acuitas Therapeutics, Inc. |
Novel carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids
|
|
US11421011B2
(en)
|
2017-05-18 |
2022-08-23 |
Modernatx, Inc. |
Polynucleotides encoding tethered interleukin-12 (IL12) polypeptides and uses thereof
|
|
US11485972B2
(en)
|
2017-05-18 |
2022-11-01 |
Modernatx, Inc. |
Modified messenger RNA comprising functional RNA elements
|
|
EP3638678B1
(en)
|
2017-06-14 |
2025-12-03 |
ModernaTX, Inc. |
Compounds and compositions for intracellular delivery of agents
|
|
EP3638292A1
(en)
|
2017-06-14 |
2020-04-22 |
ModernaTX, Inc. |
Polynucleotides encoding coagulation factor viii
|
|
EP4219715A3
(en)
|
2017-09-08 |
2023-09-06 |
MiNA Therapeutics Limited |
Stabilized cebpa sarna compositions and methods of use
|
|
EP4183882A1
(en)
|
2017-09-08 |
2023-05-24 |
MiNA Therapeutics Limited |
Stabilized hnf4a sarna compositions and methods of use
|
|
CN109771658B
(zh)
*
|
2017-11-14 |
2021-12-10 |
博瑞生物医药(苏州)股份有限公司 |
靶向多臂偶联物
|
|
US11939601B2
(en)
|
2017-11-22 |
2024-03-26 |
Modernatx, Inc. |
Polynucleotides encoding phenylalanine hydroxylase for the treatment of phenylketonuria
|
|
JP7423522B2
(ja)
|
2017-11-22 |
2024-01-29 |
モダーナティエックス・インコーポレイテッド |
尿素サイクル異常症の治療のためのオルニチントランスカルバミラーゼをコードするポリヌクレオチド
|
|
WO2019104195A1
(en)
|
2017-11-22 |
2019-05-31 |
Modernatx, Inc. |
Polynucleotides encoding propionyl-coa carboxylase alpha and beta subunits for the treatment of propionic acidemia
|
|
US11802146B2
(en)
|
2018-01-05 |
2023-10-31 |
Modernatx, Inc. |
Polynucleotides encoding anti-chikungunya virus antibodies
|
|
CN111868093A
(zh)
*
|
2018-01-30 |
2020-10-30 |
国立大学法人大阪大学 |
抗癌剂
|
|
AU2019247655A1
(en)
|
2018-04-03 |
2020-10-01 |
Vaxess Technologies, Inc. |
Microneedle comprising silk fibroin applied to a dissolvable base
|
|
EP3773745A1
(en)
|
2018-04-11 |
2021-02-17 |
ModernaTX, Inc. |
Messenger rna comprising functional rna elements
|
|
US11566246B2
(en)
|
2018-04-12 |
2023-01-31 |
Mina Therapeutics Limited |
SIRT1-saRNA compositions and methods of use
|
|
CA3100050A1
(en)
|
2018-05-11 |
2019-11-14 |
Lupagen, Inc. |
Systems and methods for closed loop, real-time modifications of patient cells
|
|
CN112654710A
(zh)
|
2018-05-16 |
2021-04-13 |
辛瑟高公司 |
用于指导rna设计和使用的方法和系统
|
|
WO2019226650A1
(en)
|
2018-05-23 |
2019-11-28 |
Modernatx, Inc. |
Delivery of dna
|
|
US20220184185A1
(en)
|
2018-07-25 |
2022-06-16 |
Modernatx, Inc. |
Mrna based enzyme replacement therapy combined with a pharmacological chaperone for the treatment of lysosomal storage disorders
|
|
JP2021534101A
(ja)
|
2018-08-09 |
2021-12-09 |
ヴェルソー セラピューティクス, インコーポレイテッド |
Ccr2及びcsf1rを標的とするためのオリゴヌクレオチド組成物ならびにその使用
|
|
MA53545A
(fr)
|
2018-09-02 |
2021-07-14 |
Modernatx Inc |
Polynucléotides codant pour l'acyl-coa déshydrogénase à très longue chaîne pour le traitement de l'insuffisance en acyl-coa déshydrogénase à très longue chaîne
|
|
MX2021003015A
(es)
|
2018-09-13 |
2021-07-15 |
Modernatx Inc |
Polinucleotidos que codifican glucosa-6-fosfatasa para el tratamiento de la glucogenosis.
|
|
EP3849594A2
(en)
|
2018-09-13 |
2021-07-21 |
Modernatx, Inc. |
Polynucleotides encoding branched-chain alpha-ketoacid dehydrogenase complex e1-alpha, e1-beta, and e2 subunits for the treatment of maple syrup urine disease
|
|
AU2019339430A1
(en)
|
2018-09-14 |
2021-04-29 |
Modernatx, Inc. |
Polynucleotides encoding uridine diphosphate glycosyltransferase 1 family, polypeptide A1 for the treatment of Crigler-Najjar Syndrome
|
|
WO2020061284A1
(en)
|
2018-09-19 |
2020-03-26 |
Modernatx, Inc. |
Peg lipids and uses thereof
|
|
EP3853202A1
(en)
|
2018-09-19 |
2021-07-28 |
ModernaTX, Inc. |
Compounds and compositions for intracellular delivery of therapeutic agents
|
|
EP4509118A3
(en)
|
2018-09-19 |
2025-05-14 |
ModernaTX, Inc. |
High-purity peg lipids and uses thereof
|
|
EP4613367A1
(en)
|
2018-09-21 |
2025-09-10 |
Acuitas Therapeutics, Inc. |
Systems and methods for manufacturing lipid nanoparticles and liposomes
|
|
MA53734A
(fr)
|
2018-09-27 |
2021-08-04 |
Modernatx Inc |
Polynucléotides codant pour l'arginase 1 pour le traitement d'une déficience en arginase
|
|
CN109010845B
(zh)
*
|
2018-09-28 |
2021-11-30 |
青岛大学 |
一种抗肿瘤药物的改性方法
|
|
WO2020097409A2
(en)
|
2018-11-08 |
2020-05-14 |
Modernatx, Inc. |
Use of mrna encoding ox40l to treat cancer in human patients
|
|
US20220031863A1
(en)
*
|
2018-12-03 |
2022-02-03 |
Master Dynamic Limited |
Nanoparticle delivery system
|
|
CA3125485A1
(en)
|
2019-01-11 |
2020-07-16 |
Acuitas Therapeutics, Inc. |
Lipids for lipid nanoparticle delivery of active agents
|
|
CN113874503A
(zh)
|
2019-01-25 |
2021-12-31 |
辛瑟高公司 |
用于调节crispr活性的系统和方法
|
|
WO2020208361A1
(en)
|
2019-04-12 |
2020-10-15 |
Mina Therapeutics Limited |
Sirt1-sarna compositions and methods of use
|
|
JP2022532078A
(ja)
|
2019-05-08 |
2022-07-13 |
アストラゼネカ アクチボラグ |
皮膚及び創傷のための組成物並びにその使用の方法
|
|
MA56539A
(fr)
|
2019-06-24 |
2022-04-27 |
Modernatx Inc |
Arn messager résistant à l'endonucléase et utilisations correspondantes
|
|
US20220387628A1
(en)
|
2019-06-24 |
2022-12-08 |
Modernatx, Inc. |
Messenger rna comprising functional rna elements and uses thereof
|
|
KR20220034717A
(ko)
|
2019-07-19 |
2022-03-18 |
신테고 코포레이션 |
안정화된 crispr 복합체
|
|
FI129022B
(en)
|
2019-09-10 |
2021-05-14 |
Aabo Akademi Univ |
Polymer and composition made from a renewable source
|
|
BR112022004759A2
(pt)
|
2019-09-19 |
2022-06-21 |
Modernatx Inc |
Composições e compostos lipídicos com cauda ramificada para entrega intracelular de agentes terapêuticos
|
|
CA3147643A1
(en)
|
2019-09-23 |
2021-04-01 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating hepatocyte nuclear factor 4-alpha (hnf4.alpha.) gene expression
|
|
EP4048807A1
(en)
|
2019-09-23 |
2022-08-31 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating apolipoprotein b (apob) gene expression
|
|
US11633405B2
(en)
|
2020-02-07 |
2023-04-25 |
Therapeuticsmd, Inc. |
Steroid hormone pharmaceutical formulations
|
|
EP4118207A1
(en)
|
2020-03-11 |
2023-01-18 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating forkhead box p3 (foxp3) gene expression
|
|
US20230235298A1
(en)
|
2020-06-01 |
2023-07-27 |
Modernatx, Inc. |
Phenylalanine hydroxylase variants and uses thereof
|
|
DK4182297T3
(da)
|
2020-07-16 |
2025-12-01 |
Acuitas Therapeutics Inc |
Kationiske lipider til brug i lipid-nanopartikler
|
|
US20230310647A1
(en)
*
|
2020-08-19 |
2023-10-05 |
The Trustees Of The University Of Pennsylvania |
Targeting cartilage egfr pathway for osteoarthritis treatment
|
|
JP2023544201A
(ja)
|
2020-10-08 |
2023-10-20 |
ターグイミューン セラピューティクス アクチエンゲゼルシャフト |
がんを処置するための免疫療法
|
|
CR20230204A
(es)
|
2020-10-14 |
2023-10-11 |
Viridian Therapeutics Inc |
Composiciones y métodos para el tratamiento de la enfermedad ocular tiroidea
|
|
US20230406895A1
(en)
|
2020-11-13 |
2023-12-21 |
Modernatx, Inc. |
Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of cystic fibrosis
|
|
GB2603454A
(en)
|
2020-12-09 |
2022-08-10 |
Ucl Business Ltd |
Novel therapeutics for the treatment of neurodegenerative disorders
|
|
CN112675313A
(zh)
*
|
2020-12-28 |
2021-04-20 |
烟台大学 |
连接曲妥珠单抗片段的美登素纳米粒组合物
|
|
CN112535678A
(zh)
*
|
2020-12-28 |
2021-03-23 |
烟台大学 |
连接曲妥珠单抗的美登素纳米粒组合物
|
|
US11524023B2
(en)
|
2021-02-19 |
2022-12-13 |
Modernatx, Inc. |
Lipid nanoparticle compositions and methods of formulating the same
|
|
US20240216288A1
(en)
|
2021-03-24 |
2024-07-04 |
Modernatx, Inc. |
Lipid nanoparticles containing polynucleotides encoding propionyl-coa carboxylase alpha and beta subunits and uses thereof
|
|
US20240226025A1
(en)
|
2021-03-24 |
2024-07-11 |
Modernatx, Inc. |
Polynucleotides encoding methylmalonyl-coa mutase for the treatment of methylmalonic acidemia
|
|
WO2022204390A1
(en)
|
2021-03-24 |
2022-09-29 |
Modernatx, Inc. |
Lipid nanoparticles containing polynucleotides encoding phenylalanine hydroxylase and uses thereof
|
|
US20240189449A1
(en)
|
2021-03-24 |
2024-06-13 |
Modernatx, Inc. |
Lipid nanoparticles and polynucleotides encoding ornithine transcarbamylase for the treatment of ornithine transcarbamylase deficiency
|
|
WO2022204371A1
(en)
|
2021-03-24 |
2022-09-29 |
Modernatx, Inc. |
Lipid nanoparticles containing polynucleotides encoding glucose-6-phosphatase and uses thereof
|
|
JP2024511092A
(ja)
|
2021-03-26 |
2024-03-12 |
ミナ セラピューティクス リミテッド |
TMEM173saRNA組成物及び使用方法
|
|
WO2022240806A1
(en)
|
2021-05-11 |
2022-11-17 |
Modernatx, Inc. |
Non-viral delivery of dna for prolonged polypeptide expression in vivo
|
|
WO2022266083A2
(en)
|
2021-06-15 |
2022-12-22 |
Modernatx, Inc. |
Engineered polynucleotides for cell-type or microenvironment-specific expression
|
|
US20240376445A1
(en)
|
2021-06-22 |
2024-11-14 |
Modernatx, Inc. |
Polynucleotides encoding uridine diphosphate glycosyltransferase 1 family, polypeptide a1 for the treatment of crigler-najjar syndrome
|
|
WO2023283359A2
(en)
|
2021-07-07 |
2023-01-12 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating secreted frizzled receptor protein 1 (sfrp1) gene expression
|
|
US20240342206A1
(en)
|
2021-07-30 |
2024-10-17 |
CureVac SE |
mRNAS FOR TREATMENT OR PROPHYLAXIS OF LIVER DISEASES
|
|
TW202320850A
(zh)
|
2021-08-10 |
2023-06-01 |
美商維里迪恩醫療股份有限公司 |
用於治療甲狀腺眼病之組合物、劑量及方法
|
|
US20250017867A1
(en)
|
2021-10-01 |
2025-01-16 |
Modernatx, Inc. |
Polynucleotides encoding relaxin for the treatment of fibrosis and/or cardiovascular disease
|
|
CA3237153A1
(en)
|
2021-11-05 |
2023-05-11 |
Targimmune Therapeutics Ag |
Targeted linear conjugates comprising polyethyleneimine and polyethylene glycol and polyplexes comprising the same
|
|
WO2023099884A1
(en)
|
2021-12-01 |
2023-06-08 |
Mina Therapeutics Limited |
Pax6 sarna compositions and methods of use
|
|
GB202117758D0
(en)
|
2021-12-09 |
2022-01-26 |
Ucl Business Ltd |
Therapeutics for the treatment of neurodegenerative disorders
|
|
WO2023114943A2
(en)
|
2021-12-16 |
2023-06-22 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
WO2023144193A1
(en)
|
2022-01-25 |
2023-08-03 |
CureVac SE |
Mrnas for treatment of hereditary tyrosinemia type i
|
|
EP4482962A1
(en)
|
2022-02-24 |
2025-01-01 |
IO Biotech ApS |
Nucleotide delivery of cancer therapy
|
|
WO2023170435A1
(en)
|
2022-03-07 |
2023-09-14 |
Mina Therapeutics Limited |
Il10 sarna compositions and methods of use
|
|
EP4499153A2
(en)
|
2022-03-25 |
2025-02-05 |
ModernaTX, Inc. |
Polynucleotides encoding fanconi anemia, complementation group proteins for the treatment of fanconi anemia
|
|
WO2023196399A1
(en)
|
2022-04-06 |
2023-10-12 |
Modernatx, Inc. |
Lipid nanoparticles and polynucleotides encoding argininosuccinate lyase for the treatment of argininosuccinic aciduria
|
|
WO2023215498A2
(en)
|
2022-05-05 |
2023-11-09 |
Modernatx, Inc. |
Compositions and methods for cd28 antagonism
|
|
WO2023250117A2
(en)
|
2022-06-24 |
2023-12-28 |
Vaxess Technologies, Inc. |
Applicator for medicament patch
|
|
MA71619A
(fr)
|
2022-07-26 |
2025-05-30 |
Modernatx, Inc. |
Polynucléotides modifiés pour la régulation temporelle de l'expression
|
|
WO2024097639A1
(en)
|
2022-10-31 |
2024-05-10 |
Modernatx, Inc. |
Hsa-binding antibodies and binding proteins and uses thereof
|
|
AU2023376546A1
(en)
|
2022-11-07 |
2025-05-15 |
Targimmune Therapeutics Ag |
Targeted linear conjugates comprising polyethyleneimine and polyethylene glycol and polyplexes comprising the same
|
|
AU2023376540A1
(en)
|
2022-11-07 |
2025-05-15 |
Targimmune Therapeutics Ag |
Psma-targeting linear conjugates comprising polyethyleneimine and polyethylene glycol and polyplexes comprising the same
|
|
IL320618A
(en)
|
2022-11-07 |
2025-07-01 |
Targimmune Therapeutics Ag |
Polyplexes of nucleic acids and targeted pairs containing polyethyleneimine and polyethylene glycol
|
|
WO2024118866A1
(en)
|
2022-12-01 |
2024-06-06 |
Modernatx, Inc. |
Gpc3-specific antibodies, binding domains, and related proteins and uses thereof
|
|
TW202440929A
(zh)
|
2022-12-14 |
2024-10-16 |
加拿大商普羅維登斯治療控股公司 |
用於感染性疾病的組合物和方法
|
|
WO2024130158A1
(en)
|
2022-12-16 |
2024-06-20 |
Modernatx, Inc. |
Lipid nanoparticles and polynucleotides encoding extended serum half-life interleukin-22 for the treatment of metabolic disease
|
|
CN115804762B
(zh)
*
|
2022-12-20 |
2024-05-31 |
浙江大学 |
一种巨噬细胞膜包覆的异位子宫内膜靶向纳米粒、制备方法及应用
|
|
WO2024134199A1
(en)
|
2022-12-22 |
2024-06-27 |
Mina Therapeutics Limited |
Chemically modified sarna compositions and methods of use
|
|
WO2024182301A2
(en)
|
2023-02-27 |
2024-09-06 |
Modernatx, Inc. |
Lipid nanoparticles and polynucleotides encoding galactose-1-phosphate uridylyltransferase (galt) for the treatment of galactosemia
|
|
WO2024197033A1
(en)
|
2023-03-21 |
2024-09-26 |
Modernatx, Inc. |
Polynucleotides encoding relaxin for the treatment of heart failure
|
|
JPWO2024204685A1
(pl)
|
2023-03-31 |
2024-10-03 |
|
|
|
WO2024229321A1
(en)
|
2023-05-03 |
2024-11-07 |
Modernatx, Inc. |
Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of cystic fibrosis
|
|
WO2024243438A2
(en)
|
2023-05-23 |
2024-11-28 |
Omega Therapeutics, Inc. |
Compositions and methods for reducing cxcl9, cxcl10, and cxcl11 gene expression
|
|
KR20260021782A
(ko)
|
2023-06-23 |
2026-02-13 |
백세스 테크놀로지스, 인코포레이티드 |
약물 패치용 도포기
|
|
EP4520345A1
(en)
|
2023-09-06 |
2025-03-12 |
Myneo Nv |
Product
|
|
WO2025072482A1
(en)
|
2023-09-27 |
2025-04-03 |
Modernatx, Inc. |
Immunoglobulin a protease polypeptides, polynucleotides, and uses thereof
|
|
CN117224705A
(zh)
*
|
2023-10-23 |
2023-12-15 |
西电集团医院 |
一种乏氧肿瘤细胞靶向和高效放射增敏的纳米粒及其制备方法
|
|
CN117838672B
(zh)
*
|
2024-03-07 |
2024-05-10 |
山东第二医科大学 |
一种替米考星/g型褐藻寡糖雾化吸入纳米混悬液及其制备方法
|
|
WO2025238236A1
(en)
|
2024-05-16 |
2025-11-20 |
Targimmune Therapeutics Ag |
Polyplexes of nucleic acids and targeted conjugates comprising polyethyleneimine and polyethylene glycol
|
|
WO2025255199A1
(en)
|
2024-06-05 |
2025-12-11 |
Modernatx, Inc. |
Argininosuccinate synthase 1 and argininosuccinate lyase polypeptides and polynucleotides and uses thereof
|
|
WO2026027887A2
(en)
|
2024-08-02 |
2026-02-05 |
Mina Therapeutics Limited |
Hbg1/2-sarna compositions and methods of use
|