MX340363B - Compuestos de oligonucleotidos inmuno-reguladores (iro) que modulan la respuesta inmune basada en receptores tipo toll. - Google Patents

Compuestos de oligonucleotidos inmuno-reguladores (iro) que modulan la respuesta inmune basada en receptores tipo toll.

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Publication number
MX340363B
MX340363B MX2013005667A MX2013005667A MX340363B MX 340363 B MX340363 B MX 340363B MX 2013005667 A MX2013005667 A MX 2013005667A MX 2013005667 A MX2013005667 A MX 2013005667A MX 340363 B MX340363 B MX 340363B
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Mexico
Prior art keywords
iro
compounds
receptor based
immune response
regulatory oligonucleotide
Prior art date
Application number
MX2013005667A
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English (en)
Other versions
MX2013005667A (es
Inventor
Sudhir Agrawal
Ekambar R Kandimalla
Daqing Wang
Ireneusz Nowak
Original Assignee
Idera Pharmaceuticals Inc
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Publication date
Application filed by Idera Pharmaceuticals Inc filed Critical Idera Pharmaceuticals Inc
Publication of MX2013005667A publication Critical patent/MX2013005667A/es
Publication of MX340363B publication Critical patent/MX340363B/es

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Abstract

La presente invención se refiere a oligonucleótidos inmuno-reguladores (IRO) novedosos como antagonistas de TLRs, y métodos de uso de los mismos; estos IROs tienen secuencias únicas que inhiben o suprimen la señalización mediada por TLR en respuesta a un ligando de TLR o agonista de TLR; los métodos pueden tener uso en la prevención y el tratamiento de cáncer, un trastorno autoinmune, inflamación de vías respiratorias, trastornos inflamatorios, enfermedad infecciosa, trastornos de la piel, alergia, asma o una enfermedad causada por un patógeno.
MX2013005667A 2010-11-19 2011-11-18 Compuestos de oligonucleotidos inmuno-reguladores (iro) que modulan la respuesta inmune basada en receptores tipo toll. MX340363B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41549410P 2010-11-19 2010-11-19
US201161511709P 2011-07-26 2011-07-26
PCT/US2011/061412 WO2012068470A2 (en) 2010-11-19 2011-11-18 Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response

Publications (2)

Publication Number Publication Date
MX2013005667A MX2013005667A (es) 2013-07-05
MX340363B true MX340363B (es) 2016-07-06

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MX2013005667A MX340363B (es) 2010-11-19 2011-11-18 Compuestos de oligonucleotidos inmuno-reguladores (iro) que modulan la respuesta inmune basada en receptores tipo toll.

Country Status (10)

Country Link
US (5) US8486908B2 (es)
EP (2) EP3213770B1 (es)
JP (1) JP5813778B2 (es)
KR (2) KR102100110B1 (es)
CN (2) CN103415302A (es)
AU (4) AU2011329668B2 (es)
CA (1) CA2817891C (es)
ES (1) ES2697606T3 (es)
MX (1) MX340363B (es)
WO (1) WO2012068470A2 (es)

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